Thialysine N-epsilon-acetyltransferase

A thialysine N-epsilon-acetyltransferase that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q96F10]

EC 2.3.1.-;
Diamine acetyltransferase 2;
2.3.1.57;
Spermidine/spermine N(1)-acetyltransferase 2;
SSAT-2

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
trientine	Homo sapiens (human)	Km	2,500.0000	1	1

This protein enables 4 target(s):

Target	Category	Definition
diamine N-acetyltransferase activity	molecular function	Catalysis of the reaction: acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine. [EC:2.3.1.57]
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
N-acetyltransferase activity	molecular function	Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule. [GOC:ai]
identical protein binding	molecular function	Binding to an identical protein or proteins. [GOC:jl]

This protein is located in 2 target(s):

Target	Category	Definition
cytoplasm	cellular component	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
extracellular exosome	cellular component	A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]

This protein is involved in 4 target(s):

Target	Category	Definition
spermidine acetylation	biological process	The modification of spermidine by addition of acetyl groups. [GOC:mlg]
spermine acetylation	biological process	The modification of spermine by addition of acetyl groups. [GOC:mlg]
putrescine acetylation	biological process	The modification of putrescine by addition of acetyl groups. [GOC:mlg]
nor-spermidine metabolic process	biological process	The chemical reactions and pathways involving nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane. [GOC:ai]