Page last updated: 2024-08-07 10:07:28

Solute carrier family 5 member 4

A probable glucose sensor protein SLC5A4 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9NY91]

Synonyms

Research

Bioassay Publications (3)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Compounds (4)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
phlorhizinHomo sapiens (human)IC500.016011
sergliflozin etabonateHomo sapiens (human)IC500.260011
dapagliflozinHomo sapiens (human)IC500.001411
pf 04971729Homo sapiens (human)IC500.000911

Enables

This protein enables 2 target(s):

TargetCategoryDefinition
protein bindingmolecular functionBinding to a protein. [GOC:go_curators]
proton transmembrane transporter activitymolecular functionEnables the transfer of a proton from one side of a membrane to the other. [GOC:ai]

Active In

This protein is active in 1 target(s):

TargetCategoryDefinition
plasma membranecellular componentThe membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]

Involved In

This protein is involved in 3 target(s):

TargetCategoryDefinition
sodium ion transmembrane transportbiological processA process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. [GOC:vw]
proton transmembrane transportbiological processThe directed movement of a proton across a membrane. [GO_REF:0000069, GOC:pr, GOC:TermGenie]
sodium ion transportbiological processThe directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]