isoniazid has been researched along with Sensitivity and Specificity in 342 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "For rifampicin, the majority of the studies that applied NRA to isolates had a sensitivity and specificity >94% and for isoniazid, >92%." | 8.84 | The nitrate reductase assay for the rapid detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis. ( Angeby, K; Hoffner, S; Martin, A; Palomino, JC; Panaiotov, S; Portaels, F, 2008) |
| "The MeltPro TB/INH assay, recently approved by the Chinese Food and Drug Administration, is a closed-tube, dual-color, melting curve analysis-based, real-time PCR test specially designed to detect 30 isoniazid (INH) resistance mutations in katG position 315 (katG 315), the inhA promoter (positions -17 to -8), inhA position 94, and the ahpC promoter (positions -44 to -30 and -15 to 3) of Mycobacterium tuberculosis." | 7.80 | Rapid detection of isoniazid resistance in Mycobacterium tuberculosis isolates by use of real-time-PCR-based melting curve analysis. ( Hu, S; Li, G; Li, H; Li, Q; Liu, X; Niu, J; Quan, S; Wang, F; Wen, H; Xu, Y, 2014) |
| "Mutations at codons 526 and 531 in the rpoB gene and at 315 in the katG gene are considered diagnostic markers for resistance to rifampin and isoniazid in tuberculosis." | 7.78 | Assessing the utility of three TaqMan probes for the diagnosis of tuberculosis and resistance to rifampin and isoniazid in Veracruz, México. ( Cuellar, A; Cuevas-Cordoba, B; Enciso, A; Enciso, L; Zenteno-Cuevas, R, 2012) |
| "We evaluated high-resolution melting (HRM) curve analysis as a tool for detecting rifampin (RIF) and isoniazid (INH) resistance in Mycobacterium tuberculosis in an accurate, affordable, and rapid manner." | 7.76 | High-resolution melting curve analysis for rapid detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis clinical isolates. ( Chang, CL; Cho, EH; Choi, GE; Hwang, SH; Kim, HH; Kim, HJ; Kim, JH; Lee, EY; Lee, SM; Yi, J, 2010) |
| "Active tuberculosis (TB) must be excluded before initiating isoniazid preventive therapy (IPT) in persons infected with human immunodeficiency virus (HIV), but currently used screening strategies have poor sensitivity and specificity and high patient attrition rates." | 7.76 | Microscopic observation drug susceptibility assay for tuberculosis screening before isoniazid preventive therapy in HIV-infected persons. ( Benites, C; Brady, MF; Chavez, G; Coronel, J; Friedland, JS; Gilman, RH; Moore, DA; Navincopa, M; Pinedo, Y; Reddy, KP; Rojas, C; Sánchez, E; Solari, L; Ticona, E; Valencia, J, 2010) |
| "The aim of this study was to evaluate a simple, rapid, and inexpensive colorimetric nitrate reductase assay (NRA) for direct drug susceptibility testing (DST) of Mycobacterium tuberculosis against rifampicin (RIF) and isoniazid (INH)." | 7.76 | Evaluation of direct method of drug susceptibility testing of Mycobacterium tuberculosis to rifampicin and isoniazid by nitrate reductase assay in a national reference laboratory. ( Behera, D; Meharwal, SK; Myneedu, VP; Visalakshi, P, 2010) |
| " tuberculosis strains to isoniazid between MGIT AST and 1% Ogawa proportion method have been reported." | 7.74 | [Comparative study of bactec MGIT 960 AST and conventional proportion method using Ogawa medium for the drug susceptibility testing of Mycobacterium tuberculosis to isoniazid]. ( Abe, C; Fujii, S; Kamada, A; Kawabe, Y; Kawashiro, T; Kobayashi, I; Machida, K; Mitarai, S; Mori, K; Ogata, H; Shigetoh, E; Suyama, H; Suzuki, K; Takashima, T; Takigawa, S; Tano, M; Wada, M; Yano, S, 2007) |
| "The new GenoType MTBDRplus assay (Hain Lifescience GmbH, Nehren, Germany) was tested with 125 clinical isolates and directly with 72 smear-positive sputum specimens for its ability to detect rifampin (RMP) and isoniazid (INH) resistance in Mycobacterium tuberculosis complex (MTBC) strains." | 7.74 | Evaluation of the GenoType MTBDRplus assay for rifampin and isoniazid susceptibility testing of Mycobacterium tuberculosis strains and clinical specimens. ( Hillemann, D; Richter, E; Rüsch-Gerdes, S, 2007) |
| "The purpose of this study was to evaluate the GenoType MTBDRplus assay (Hain Lifescience GmbH, Nehren, Germany) for its ability to detect resistance to rifampin (RIF) and isoniazid (INH) in Mycobacterium tuberculosis clinical strains and directly in clinical samples." | 7.74 | GenoType MTBDRplus assay for molecular detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis strains and clinical samples. ( Domínguez, J; Garcia-Sierra, N; Haba, L; Lacoma, A; Maldonado, J; Prat, C; Rosés, S; Ruiz-Manzano, J, 2008) |
| "Isoniazid (INH) and rifampin (RIF) are two of the most important antituberculosis drugs, and resistance to both of these drugs can often result in treatment failure and fatal clinical outcome." | 7.73 | Use of smear-positive samples to assess the PCR-based genotype MTBDR assay for rapid, direct detection of the Mycobacterium tuberculosis complex as well as its resistance to isoniazid and rifampin. ( Dormandy, J; Mitsani, D; Rivenburg, J; Salfinger, M; Somoskovi, A, 2006) |
| "A novel PCR-based reverse hybridization method Genotype MTBDR assay (Hain Lifescience GmbH, Nehren, Germany) was evaluated for rapid detection of rifampin (RIF) and isoniazid (INH) resistance in Turkish Mycobacterium tuberculosis isolates." | 7.73 | Evaluation of the Genotype MTBDR assay for rapid detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis isolates. ( Akinci, P; Cavusoglu, C; Soyler, I; Turhan, A, 2006) |
| "To apply the Arkansas color method in order to evaluate drug compliance and factors that can predict treatment adherence in patients being treated for latent tuberculosis infection (LTBI) with a single daily dose of isoniazid (INH)." | 7.72 | Use of the urine color test to monitor compliance with isoniazid treatment of latent tuberculosis infection. ( Amir, J; Baum, G; Eidlitz-Markus, T; Mimouni, M; Zeharia, A, 2003) |
| "To see whether sustained levels of pyrazinamide are available for prolonged periods after a single subcutaneous administration of a biodegradable polylactic-glycolic acid (PLGA) polymer containing the drug, studies were done to ascertain whether a single administration of isoniazid and pyrazinamide in separate PLGA polymers could offer chemotherapeutic protection against a heavy intravenous challenge of susceptible mice with a virulent strain of Mycobacterium tuberculosis similar to that rendered by daily administration of the two drugs for 8 weeks." | 7.70 | Chemotherapy of tuberculosis in mice using single implants of isoniazid and pyrazinamide. ( Gangadharam, PR; Geeta, N; Hsu, YY; Wise, DL, 1999) |
| "To compare the strategy of TB vaccination with that of tuberculin skin-testing in conjunction with isoniazid (INH) in preventing tuberculosis in HIV-infected persons." | 7.70 | Tuberculosis vaccination versus isoniazid preventive therapy: a decision analysis to determine the preferred strategy of tuberculosis prevention in HIV-infected adults in the developing world. ( Brehm, WT; Chaisson, RE; Moore, RD; Sterling, TR, 1999) |
| "One of the mechanisms of isoniazid resistance to Mycobacterium tuberculosis has been proved to be the chromosomal deletion of katG." | 7.69 | KatG sequence deletion is not the major cause of isoniazid resistance in Japanese and Yemeni Mycobacterium tuberculosis isolates. ( Abe, C; Goto, M; Kimura, S; Kitada, K; Oka, S; Shimada, K; Tachikawa, N; Wada, M, 1995) |
| "Tuberculosis is a growing international health concern." | 5.35 | Genotypic detection of rifampicin and isoniazid resistant Mycobacterium tuberculosis strains by DNA sequencing: a randomized trial. ( Abdelaal, A; Badran, E; El Mashad, N; El-Ghaffar, HA; Fathy, A; Zaghloul, MH, 2009) |
| "Chemotherapy for Mycobacterium tuberculosis infection may decrease interferon (IFN)-gamma responses to early secretory antigenic target 6 and culture filtrate protein (CFP)-10; a reaction that could be useful to monitor the success of treatment." | 5.35 | Interferon-gamma responses after isoniazid chemotherapy for latent tuberculosis. ( Harada, N; Higuchi, K; Mori, T, 2008) |
| "This level of sensitivity and specificity is concordant with that from the determination of M." | 5.33 | Evaluation of the CombiChip Mycobacteria Drug-Resistance detection DNA chip for identifying mutations associated with resistance to isoniazid and rifampin in Mycobacterium tuberculosis. ( Jang, H; Kang, SJ; Kim, C; Kim, SY; Park, YJ; Song, E; Yoo, J, 2006) |
| " Loop-mediated isothermal amplification and Au-Nanoprobe showed 100% sensitivity and specificity in detecting rifampicin and isoniazid resistance." | 5.12 | Combining LAMP and Au-Nanoprobe to detect INH-RIF resistance accurately in tuberculosis: an evidence-based review. ( Ariq, H; Habiburrahman, M; Handayani, RRD, 2021) |
| "For rifampicin, the majority of the studies that applied NRA to isolates had a sensitivity and specificity >94% and for isoniazid, >92%." | 4.84 | The nitrate reductase assay for the rapid detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis. ( Angeby, K; Hoffner, S; Martin, A; Palomino, JC; Panaiotov, S; Portaels, F, 2008) |
| " The BD MAX™ multidrug resistant (MDR)-TB assay (BD MAX™) has demonstrated high sensitivity and specificity for the detection of the Mycobacterium tuberculosis complex (MTBC) as well as resistance to INH and Rifampin (RIF) in pulmonary specimens but has not been rigorously assessed in extrapulmonary samples." | 4.31 | An analytic feasibility study of the BD MAX™ MDR-TB assay for testing of non-sputum specimens for detection of the Mycobacterium tuberculosis complex (MTBC) and isoniazid (INH) and rifampin (RIF) resistance. ( Armstrong, D; Fisher, S; Parrish, N; Totten, M, 2023) |
| "Rifampicin (RIF) and isoniazid (INH) are the two most effective first-line antibiotic drugs for the treatment of tuberculosis (TB)." | 4.02 | Detection of Mycobacterium tuberculosis complex in pulmonary and extrapulmonary samples with the FluoroType MTBDR assay. ( Folkvardsen, DB; Lillebaek, T; Rasmussen, EM; Svensson, E, 2021) |
| "To evaluate performance of thin layer agar (TLA) 7H11 method for detection of ofloxacin (OFX) and kanamycin (KM) resistance in smear positive clinical specimens of patients with tuberculosis comparing the results with gold standard MGIT 960 system." | 3.91 | Evaluation of Thin Layer Agar 7H11 for Direct Susceptibility Testing of Mycobacterium Tuberculosis Complex against Second Line Anti Tuberculosis Drugs on Smear Positive Specimens. ( Gardezi, AH; Hussain, A; Ikram, A; Khadim, MT; Satti, L; Zaman, G, 2019) |
| " The respective sensitivity and specificity were 84% and 100% for isoniazid (INH); 82% and 100% for rifampin (RIF); 67% and 100% for amikacin (AK); and both 100% for ofloxacin (OFX)." | 3.88 | Evaluation of Nitrate Reductase Assay for Early Detection of Multi and Extensively Drug Resistance Tuberculosis in our Setup. ( Ahmed, P; Gardezi, AH; Ikram, AI; Lalani, FK; Satti, ML; Zaman, G, 2018) |
| "The sensitivity and specificity of MTBDRplus in detecting isoniazid (INH) resistance were 96." | 3.85 | Performance of MTBDRplus assay in detecting multidrug resistant tuberculosis at hospital level. ( Ameni, G; Assefa, M; Demisse, D; Getachew, Z; Kebede, A; Tedla, Y; Yenew, B, 2017) |
| "Isoniazid preventive therapy (IPT) is effective for preventing active tuberculosis (TB), although its mechanism of action is poorly understood and the optimal disease burden for IPT use has not been defined." | 3.85 | Is IPT more effective in high-burden settings? Modelling the effect of tuberculosis incidence on IPT impact. ( Denholm, JT; Handel, A; Houben, RM; McBryde, ES; Ragonnet, R; Sumner, T; Trauer, JM, 2017) |
| "NAT2 genotype is an indicator for isoniazid dosage adjusting for tuberculosis treatment." | 3.83 | Rapid identification of the NAT2 genotype in tuberculosis patients by multicolor melting curve analysis. ( Chen, S; Dai, G; Dong, L; Hu, Y; Huang, H; Li, Y; Yu, X; Zhao, L, 2016) |
| "Symptom-based tuberculosis screening identifies less than one-third of eligible HIV-infected patients as candidates for isoniazid preventive therapy (IPT)." | 3.80 | Point-of-care C-reactive protein testing to facilitate implementation of isoniazid preventive therapy for people living with HIV. ( Bangsberg, DR; Byakwaga, H; Cattamanchi, A; Davis, JL; Huang, L; Hunt, PW; Martin, JN; Muzoora, C; Nahid, P; Scibetta, C; Semitala, FC; Yoon, C, 2014) |
| "The MeltPro TB/INH assay, recently approved by the Chinese Food and Drug Administration, is a closed-tube, dual-color, melting curve analysis-based, real-time PCR test specially designed to detect 30 isoniazid (INH) resistance mutations in katG position 315 (katG 315), the inhA promoter (positions -17 to -8), inhA position 94, and the ahpC promoter (positions -44 to -30 and -15 to 3) of Mycobacterium tuberculosis." | 3.80 | Rapid detection of isoniazid resistance in Mycobacterium tuberculosis isolates by use of real-time-PCR-based melting curve analysis. ( Hu, S; Li, G; Li, H; Li, Q; Liu, X; Niu, J; Quan, S; Wang, F; Wen, H; Xu, Y, 2014) |
| "To evaluate the cost-effectiveness of the Three I's for HIV/TB (human immunodeficiency virus/tuberculosis): antiretroviral therapy (ART), intensified TB case finding (ICF), isoniazid preventive treatment (IPT), and TB infection control (IC)." | 3.80 | Cost-effectiveness of the Three I's for HIV/TB and ART to prevent TB among people living with HIV. ( Abimbola, T; Bennett, R; Date, A; Granich, R; Gupta, S; Sangrujee, N; Suthar, AB, 2014) |
| "To assess the cost-effectiveness ratio of rifampin for 4 months and isoniazid for 6 months in contacts with latent tuberculosis infection." | 3.79 | Cost-effectiveness of rifampin for 4 months and isoniazid for 6 months in the treatment of tuberculosis infection. ( Clotet, L; Domínguez, A; Ferrer, A; Garrido, P; Pina, JM; Sala, MR; Salleras, L, 2013) |
| "Poor adherence to isoniazid (INH) preventive therapy (IPT) is an impediment to effective control of latent tuberculosis (TB) infection." | 3.78 | Point-of-care urine tests for smoking status and isoniazid treatment monitoring in adult patients. ( Menzies, D; Nicolau, I; Ostiguy, G; Pai, M; Tian, L, 2012) |
| " tuberculosis by MTBDRplus, this assay's sensitivity and specificity for rifampin resistance were 85." | 3.78 | Genotype MTBDRplus for direct detection of Mycobacterium tuberculosis and drug resistance in strains from gold miners in South Africa. ( Beylis, N; Chihota, VN; Churchyard, GJ; Dorman, SE; Fielding, KL; Grant, AD; Lewis, JJ; Mathema, B; van der Meulen, M, 2012) |
| "Mutations at codons 526 and 531 in the rpoB gene and at 315 in the katG gene are considered diagnostic markers for resistance to rifampin and isoniazid in tuberculosis." | 3.78 | Assessing the utility of three TaqMan probes for the diagnosis of tuberculosis and resistance to rifampin and isoniazid in Veracruz, México. ( Cuellar, A; Cuevas-Cordoba, B; Enciso, A; Enciso, L; Zenteno-Cuevas, R, 2012) |
| "Regimens for isoniazid-based preventive therapy (IPT) for tuberculosis (TB) in HIV-infected individuals have not been widely adopted given concerns regarding efficacy, adherence and drug resistance." | 3.78 | The cost-effectiveness of tuberculosis preventive therapy for HIV-infected individuals in southern India: a trial-based analysis. ( Freedberg, KA; Kumarasamy, N; Losina, E; Mayer, KH; Pho, MT; Ponnuraja, C; Scott, CA; Swaminathan, S; Uhler, LM; Walensky, RP, 2012) |
| "In the present study, sensitivity and specificity of the phage assay when compared to proportion method were in the range of 97 to 100 per cent for all the drugs except for ciprofloxacin for which it was 93 and 96 per cent, respectively." | 3.78 | In-house, simple & economical phage technique for rapid detection of rifampicin, isoniazid, ethambutol, streptomycin & ciprofloxacin drug resistance using Mycobacterium tuberculosis isolates. ( Chitnis, DS; Hemvani, N; Patidar, V, 2012) |
| "Active tuberculosis (TB) must be excluded before initiating isoniazid preventive therapy (IPT) in persons infected with human immunodeficiency virus (HIV), but currently used screening strategies have poor sensitivity and specificity and high patient attrition rates." | 3.76 | Microscopic observation drug susceptibility assay for tuberculosis screening before isoniazid preventive therapy in HIV-infected persons. ( Benites, C; Brady, MF; Chavez, G; Coronel, J; Friedland, JS; Gilman, RH; Moore, DA; Navincopa, M; Pinedo, Y; Reddy, KP; Rojas, C; Sánchez, E; Solari, L; Ticona, E; Valencia, J, 2010) |
| "The aim of this study was to evaluate a simple, rapid, and inexpensive colorimetric nitrate reductase assay (NRA) for direct drug susceptibility testing (DST) of Mycobacterium tuberculosis against rifampicin (RIF) and isoniazid (INH)." | 3.76 | Evaluation of direct method of drug susceptibility testing of Mycobacterium tuberculosis to rifampicin and isoniazid by nitrate reductase assay in a national reference laboratory. ( Behera, D; Meharwal, SK; Myneedu, VP; Visalakshi, P, 2010) |
| "We evaluated high-resolution melting (HRM) curve analysis as a tool for detecting rifampin (RIF) and isoniazid (INH) resistance in Mycobacterium tuberculosis in an accurate, affordable, and rapid manner." | 3.76 | High-resolution melting curve analysis for rapid detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis clinical isolates. ( Chang, CL; Cho, EH; Choi, GE; Hwang, SH; Kim, HH; Kim, HJ; Kim, JH; Lee, EY; Lee, SM; Yi, J, 2010) |
| "In this study, a pyrosequencing method for monitoring two genes related to isoniazid (INH)-resistance and a region of the rpoB gene linked to rifampin (RMP)-resistance in Mycobacterium tuberculosis was developed and evaluated." | 3.76 | A pyrosequencing method for molecular monitoring of regions in the inhA, ahpC and rpoB genes of Mycobacterium tuberculosis. ( Bocanegra-García, V; Cruz-Pulido, W; Garza-González, E; González, GM; Rentería, A; Rivera, G, 2010) |
| "Chest radiography is used to screen for tuberculosis (TB) in asymptomatic persons living with the human immunodeficiency virus (PLWH) seeking isoniazid preventive therapy (IPT)." | 3.76 | Association of chest radiographic abnormalities with tuberculosis disease in asymptomatic HIV-infected adults. ( Agizew, T; Bachhuber, MA; Makwaruzi, VZ; Mboya, JJ; Nyirenda, S; Parker, JE; Samandari, T; Tallaksen, RJ; Tedla, Z, 2010) |
| "The purpose of this study was to evaluate the GenoType MTBDRplus assay (Hain Lifescience GmbH, Nehren, Germany) for its ability to detect resistance to rifampin (RIF) and isoniazid (INH) in Mycobacterium tuberculosis clinical strains and directly in clinical samples." | 3.74 | GenoType MTBDRplus assay for molecular detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis strains and clinical samples. ( Domínguez, J; Garcia-Sierra, N; Haba, L; Lacoma, A; Maldonado, J; Prat, C; Rosés, S; Ruiz-Manzano, J, 2008) |
| "The sensitivity and specificity of the resazurin test were studied in 77 strains and were respectively 95% and 97." | 3.74 | Evaluation of the resazurin assay for the detection of multidrug-resistant Mycobacterium tuberculosis in Madagascar. ( Martin, A; Portaels, F; Ramarokoto, H; Rasolofo Razanamparany, V; Rasolonavalona, T; Ravololonandriana, P; Rivoire, N, 2007) |
| "The new GenoType MTBDRplus assay (Hain Lifescience GmbH, Nehren, Germany) was tested with 125 clinical isolates and directly with 72 smear-positive sputum specimens for its ability to detect rifampin (RMP) and isoniazid (INH) resistance in Mycobacterium tuberculosis complex (MTBC) strains." | 3.74 | Evaluation of the GenoType MTBDRplus assay for rifampin and isoniazid susceptibility testing of Mycobacterium tuberculosis strains and clinical specimens. ( Hillemann, D; Richter, E; Rüsch-Gerdes, S, 2007) |
| " tuberculosis strains to isoniazid between MGIT AST and 1% Ogawa proportion method have been reported." | 3.74 | [Comparative study of bactec MGIT 960 AST and conventional proportion method using Ogawa medium for the drug susceptibility testing of Mycobacterium tuberculosis to isoniazid]. ( Abe, C; Fujii, S; Kamada, A; Kawabe, Y; Kawashiro, T; Kobayashi, I; Machida, K; Mitarai, S; Mori, K; Ogata, H; Shigetoh, E; Suyama, H; Suzuki, K; Takashima, T; Takigawa, S; Tano, M; Wada, M; Yano, S, 2007) |
| "To determine the sensitivity and specificity of the Arkansas method for detecting isoniazid (INH) metabolites among South African adults and to examine the effect of smoking status on positive results." | 3.74 | Evaluation of the Arkansas method of urine testing for isoniazid in South Africa. ( Churchyard, G; Fielding, K; Grant, AD; Hanifa, Y; Lewis, J; Mngadi, K, 2007) |
| "A novel PCR-based reverse hybridization method Genotype MTBDR assay (Hain Lifescience GmbH, Nehren, Germany) was evaluated for rapid detection of rifampin (RIF) and isoniazid (INH) resistance in Turkish Mycobacterium tuberculosis isolates." | 3.73 | Evaluation of the Genotype MTBDR assay for rapid detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis isolates. ( Akinci, P; Cavusoglu, C; Soyler, I; Turhan, A, 2006) |
| "Isoniazid (INH) and rifampin (RIF) are two of the most important antituberculosis drugs, and resistance to both of these drugs can often result in treatment failure and fatal clinical outcome." | 3.73 | Use of smear-positive samples to assess the PCR-based genotype MTBDR assay for rapid, direct detection of the Mycobacterium tuberculosis complex as well as its resistance to isoniazid and rifampin. ( Dormandy, J; Mitsani, D; Rivenburg, J; Salfinger, M; Somoskovi, A, 2006) |
| " Most of the evaluated tests showed excellent performance for isoniazid and rifampicin, with sensitivity and specificity values > 90%." | 3.73 | Evaluation of rapid alternative methods for drug susceptibility testing in clinical isolates of Mycobacterium tuberculosis. ( Chiani, Y; Imaz, MS; Mengatto, L, 2006) |
| "Prospective study comparing the sensitivity and specificity of the direct Griess method with the Löwenstein-Jensen proportion method in determining resistance to isoniazid (INH) and rifampin (RMP) among clinical isolates." | 3.73 | Validation of a rapid method for detection of M. tuberculosis resistance to isoniazid and rifampin in Lima, Peru. ( Han, LL; Llanos, F; Shin, SS; Sloutsky, A; Solis, LA; Stowell, M, 2005) |
| "The results using the three methods showed a good sensitivity and specificity between 94% and 100% for the detection of rifampicin and isoniazid resistance." | 3.73 | Comparative evaluation of the nitrate reduction assay, the MTT test, and the resazurin microtitre assay for drug susceptibility testing of clinical isolates of Mycobacterium tuberculosis. ( Echemendia, M; Lemus, D; Martin, A; Montoro, E; Palomino, JC; Portaels, F, 2005) |
| "The accuracy of the Bactec MGIT 960 system for susceptibility testing of 177 clinical isolates of Mycobacterium tuberculosis to first line drugs (isoniazid, rifampicin, ethambutol and streptomycin) was compared with the agar reference method." | 3.72 | Evaluation of the fully automated Bactec MGIT 960 system for the susceptibility testing of Mycobacterium tuberculosis to first-line drugs: a multicenter study. ( Anagnostou, S; Costopoulos, C; Gitti, Z; Kontos, F; Maniati, M; Maniatis, AN; Nicolaou, S; Petinaki, E; Tselentis, I, 2004) |
| "To apply the Arkansas color method in order to evaluate drug compliance and factors that can predict treatment adherence in patients being treated for latent tuberculosis infection (LTBI) with a single daily dose of isoniazid (INH)." | 3.72 | Use of the urine color test to monitor compliance with isoniazid treatment of latent tuberculosis infection. ( Amir, J; Baum, G; Eidlitz-Markus, T; Mimouni, M; Zeharia, A, 2003) |
| "A colorimetric, microplate-based Alamar Blue assay (MABA) method was used to determine the MICs of isoniazid (INH), rifampin, streptomycin (SM), and ethambutol (EMB) for 34 Peruvian Mycobacterium tuberculosis isolates (including both pansensitive and multidrug-resistant strains) and the H37Rv strain by using bacterial suspensions prepared directly from solid media." | 3.70 | Rapid, low-technology MIC determination with clinical Mycobacterium tuberculosis isolates by using the microplate Alamar Blue assay. ( Cook, MB; Degnan, MT; Ferguson, RM; Franzblau, SG; Gilman, RH; Hernandez, A; Madico, G; McLaughlin, JC; Quenzer, VK; Torres, P; Witzig, RS, 1998) |
| "To see whether sustained levels of pyrazinamide are available for prolonged periods after a single subcutaneous administration of a biodegradable polylactic-glycolic acid (PLGA) polymer containing the drug, studies were done to ascertain whether a single administration of isoniazid and pyrazinamide in separate PLGA polymers could offer chemotherapeutic protection against a heavy intravenous challenge of susceptible mice with a virulent strain of Mycobacterium tuberculosis similar to that rendered by daily administration of the two drugs for 8 weeks." | 3.70 | Chemotherapy of tuberculosis in mice using single implants of isoniazid and pyrazinamide. ( Gangadharam, PR; Geeta, N; Hsu, YY; Wise, DL, 1999) |
| "To compare the strategy of TB vaccination with that of tuberculin skin-testing in conjunction with isoniazid (INH) in preventing tuberculosis in HIV-infected persons." | 3.70 | Tuberculosis vaccination versus isoniazid preventive therapy: a decision analysis to determine the preferred strategy of tuberculosis prevention in HIV-infected adults in the developing world. ( Brehm, WT; Chaisson, RE; Moore, RD; Sterling, TR, 1999) |
| "One of the mechanisms of isoniazid resistance to Mycobacterium tuberculosis has been proved to be the chromosomal deletion of katG." | 3.69 | KatG sequence deletion is not the major cause of isoniazid resistance in Japanese and Yemeni Mycobacterium tuberculosis isolates. ( Abe, C; Goto, M; Kimura, S; Kitada, K; Oka, S; Shimada, K; Tachikawa, N; Wada, M, 1995) |
| "Isoniazid chemoprophylaxis effectively prevents the development of active infectious tuberculosis." | 3.69 | Monitored isoniazid prophylaxis for low-risk tuberculin reactors older than 35 years of age: a risk-benefit and cost-effectiveness analysis. ( Owens, DK; Salpeter, EE; Salpeter, SR; Sanders, GD, 1997) |
| "Reference standards were culture (pulmonary tuberculosis detection); phenotypic DST (pDST), genotypic DST (gDST),composite (pDST and gDST) (drug resistance detection)." | 2.82 | Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and amikacin. ( Chaplin, M; Davies, GR; De Vos, M; Pillay, S; Schumacher, SG; Steingart, KR; Theron, G; Warren, R, 2022) |
| "For isoniazid it was 94% and 100% for NRA, 92% and 96% for MODS, 71% and 100% for Genotype MTBDR, and 96% and 100% with the Genotype MTBDRplus, respectively." | 2.45 | Direct susceptibility testing for multi drug resistant tuberculosis: a meta-analysis. ( Bwanga, F; Haile, M; Hoffner, S; Joloba, ML, 2009) |
| "The sensitivity and specificity were 97." | 1.56 | Rapid detection of Mycobacterium tuberculosis DNA and genetic markers for Isoniazid resistance in Ziehl-Neelsen stained slides. ( Barcellos, RB; Bello, GL; Dalla Costa, ER; de Almeida, IN; de Jesus, SP; de Miranda, SS; Figueiredo, LJA; Gehlen, M; Morais, FCL; Rossetti, MLR; Soares, TDS; Wolf, JM, 2020) |
| "All ciprofloxacin DST results were susceptible by both methods." | 1.56 | MDR/XDR-TB Colour Test for drug susceptibility testing of Mycobacterium tuberculosis, Northwest Ethiopia. ( Balada-Llasat, JM; Evans, CA; Gelaw, B; Kelley, HV; Shibabaw, A; Tesfaye, E; Tessema, B; Torrelles, JB; Wang, SH, 2020) |
| "Thus, the sensitivity and specificity were observed to be 100% for all three tested drugs when compared with indirect DST." | 1.51 | Direct drug susceptibility testing of Mycobacterium tuberculosis using the proportional method: A multicenter study. ( Allahyar Torkaman, MR; Amini, S; Hamzehloo, G; Hoffner, S; Mir, R; Mohsenpoor, M; Nasiri, MJ; Salehi, M; Sami Kashkooli, G; Shahraki, MS; Soleimanpour, S, 2019) |
| "The confirmatory diagnosis of pleural tuberculosis (pTB) remains challenging." | 1.51 | Epidemiology and diagnosis of pleural tuberculosis in a low incidence country with high rate of immigrant population: A retrospective study. ( Macías, A; Molina, I; Saborit, N; Salvador, F; Sánchez-Montalvá, A; Tórtola, T; Villar, A, 2019) |
| "People with HIV infection with latent tuberculosis (TB) infection (LTBI) are at a 10-fold greater risk of developing active disease." | 1.48 | New and Noteworthy in Tuberculosis Diagnostics and Treatment. ( Swindells, S, 2018) |
| "Suspected latent tuberculosis infection (LTBI) is a common reason for referral to TB clinics." | 1.39 | Does an interferon-gamma release assay change practice in possible latent tuberculosis? ( Chalmers, JD; Gilhooley, S; Hill, AT; Jones, ME; Laurenson, IF; McSparron, C; Tiernan, JF, 2013) |
| "Sensitivity and specificity were 98% and 99% respectively for detection of RIF resistance; 92% and 99% respectively for detection of INH resistance; 97% and 100% respectively for detection of MDR-TB." | 1.39 | Comparative evaluation of GenoType MTBDRplus line probe assay with solid culture method in early diagnosis of multidrug resistant tuberculosis (MDR-TB) at a tertiary care centre in India. ( Arora, SK; Hanif, M; Kumar, A; Myneedu, VP; Paramasivan, CN; Raizada, N; Sachdeva, KS; Sharma, R; Sharma, SK; Singh, BK; Sinha, S; Soneja, M; Sreenivas, V; Thakur, R; Vollepore, B; Yadav, RN, 2013) |
| "Data are sparse on Mycobacterium tuberculosis infection among patients with cancer in Egypt." | 1.38 | Characterization of Mycobacterium tuberculosis isolated from cancer patients with suspected tuberculosis infection in Egypt: identification, prevalence, risk factors and resistance pattern. ( Afifi, S; Eissa, S; El-Dahshan, R; El-Sharif, A; Rafeh, N, 2012) |
| "The sensitivity and specificity were 75-100% and 31." | 1.38 | Training laboratory technicians from the Ethiopian periphery in the MODS technique enables rapid and low-cost diagnosis of Mycobacterium tuberculosis infection. ( Block, C; Caviedes, L; Elinav, H; Kalter, HD; Lemma, E; Maayan, S; Moulton, LH; Rajs, A, 2012) |
| "Chemotherapy for Mycobacterium tuberculosis infection may decrease interferon (IFN)-gamma responses to early secretory antigenic target 6 and culture filtrate protein (CFP)-10; a reaction that could be useful to monitor the success of treatment." | 1.35 | Interferon-gamma responses after isoniazid chemotherapy for latent tuberculosis. ( Harada, N; Higuchi, K; Mori, T, 2008) |
| "Tuberculosis is a growing international health concern." | 1.35 | Genotypic detection of rifampicin and isoniazid resistant Mycobacterium tuberculosis strains by DNA sequencing: a randomized trial. ( Abdelaal, A; Badran, E; El Mashad, N; El-Ghaffar, HA; Fathy, A; Zaghloul, MH, 2009) |
| "Trifluoroacetic acid (TFA) is a commonly used additive in HPLC and LC-MS analysis of basic compounds." | 1.33 | Simple means to alleviate sensitivity loss by trifluoroacetic acid (TFA) mobile phases in the hydrophilic interaction chromatography-electrospray tandem mass spectrometric (HILIC-ESI/MS/MS) bioanalysis of basic compounds. ( Naidong, W; Shou, WZ, 2005) |
| "This level of sensitivity and specificity is concordant with that from the determination of M." | 1.33 | Evaluation of the CombiChip Mycobacteria Drug-Resistance detection DNA chip for identifying mutations associated with resistance to isoniazid and rifampin in Mycobacterium tuberculosis. ( Jang, H; Kang, SJ; Kim, C; Kim, SY; Park, YJ; Song, E; Yoo, J, 2006) |
| "In total, 45 children with pulmonary tuberculosis participated." | 1.32 | Follow-up of compliance with tuberculosis treatment in children: monitoring by urine tests. ( Gultekin, D; Kayaalp, N; Palanduz, A, 2003) |
| "Ethambutol was recovered from human urine quantitatively and stable for a period of at least one week in urine stored at -20 degrees C." | 1.32 | Standardization of the method for estimation of ethambutol in pharmaceutical preparations and biological fluid. ( Bhagavathy, S; Gayathri, TN; Gurumurthy, P; Venkatesan, P, 2004) |
| "Isoniazid was extracted from animal plasma samples using a Waters Oasis HLB 96-well plate and then eluted with acetonitrile, while cetirizine was extracted from human plasma with a Waters MCX mu-Elute plate and then eluted with acetonitrile containing 5% concentrated ammonium hydroxide." | 1.32 | Direct injection of solid-phase extraction eluents onto silica columns for the analysis of polar compounds isoniazid and cetirizine in plasma using hydrophilic interaction chromatography with tandem mass spectrometry. ( Bryant, MS; Jiang, XY; Junga, H; Li, AC; Naidong, W; Shou, WZ, 2004) |
| "A simple and accurate liquid chromatographic method was developed and validated for estimation of isoniazid (ISN), pyrazinamide (PYR) and rifampicin (RIF) in combined dosage forms." | 1.31 | Validation of a RP-LC method for the simultaneous determination of isoniazid, pyrazinamide and rifampicin in a pharmaceutical formulation. ( Caccialanza, G; Calleri, E; De Lorenzi, E; Furlanetto, S; Massolini, G, 2002) |
| "Sensitivity and specificity were estimated." | 1.31 | Urine testing to monitor adherence to TB preventive therapy. ( Berg, J; Blumberg, E; Catanzaro, A; Friedman, L; Hovell, MF; Kelley, N; Moser, K; Perry, S; Sipan, C; Vera, A, 2002) |
| "Tuberculous Meningitis is associated with a high morbidity and mortality if there is a delay in diagnosis." | 1.31 | Diagnostic criteria for Tuberculous Meningitis. ( Seth, R; Sharma, U, 2002) |
| "Although relapse was more frequent in patients with positive smears than those with negative smears (9." | 1.30 | Should we take a history of prior treatment, and check sputum status at 2-3 months when treating patients for tuberculosis? ( Bechan, S; Connolly, C; Short, GM; Standing, E; Wilkinson, D, 1998) |
| " Male and female Sprague-Dawley (CD) rats were dosed with either pregnenolone-16alpha-carbonitrile (PCN; 50 mg/kg per day for 5 days), phenobarbital (PB; 100 mg/kg per day for 4 days), beta-naphthoflavone (betaNF; 100 mg/kg per day for 3 days), clofibrate (CF; 300 mg/kg per day for 14 days), isoniazid (ISO; 100 mg/kg per day for 3 days), or dexamethasone (DEX; 50 mg/kg per day for 4 days)." | 1.30 | Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes. ( Amacher, DE; Schomaker, SJ, 1998) |
| " Thus, lower concentration of RIF may be available for absorption leading to poor bioavailability of RIF from combination dosage forms (RIF+INH) as compared to formulations containing only RIF." | 1.30 | Stability of rifampicin in dissolution medium in presence of isoniazid. ( Kotecha, JS; Rathod, IS; Savale, SS; Shah, PB; Shah, SA; Shishoo, CJ, 1999) |
| " Due to difficulties in producing effective combined formulations of these three drugs, the bioavailability of new combination formulations needs to be assessed prior to registration." | 1.30 | Determination of rifampicin, isoniazid and pyrazinamide by high performance liquid chromatography after their simultaneous extraction from plasma. ( Fredericks, A; Smith, PJ; van Dyk, J, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.29) | 18.7374 |
| 1990's | 32 (9.36) | 18.2507 |
| 2000's | 114 (33.33) | 29.6817 |
| 2010's | 155 (45.32) | 24.3611 |
| 2020's | 40 (11.70) | 2.80 |
| Authors | Studies |
|---|---|
| Gegia, M | 1 |
| Mdivani, N | 1 |
| Mendes, RE | 1 |
| Li, H | 3 |
| Akhalaia, M | 1 |
| Han, J | 1 |
| Khechinashvili, G | 1 |
| Tang, YW | 1 |
| Luo, T | 1 |
| Zhao, M | 2 |
| Li, X | 2 |
| Xu, P | 5 |
| Gui, X | 1 |
| Pickerill, S | 1 |
| DeRiemer, K | 1 |
| Mei, J | 2 |
| Gao, Q | 4 |
| Feng, G | 1 |
| Han, W | 1 |
| Shi, J | 2 |
| Xia, R | 1 |
| Xu, J | 1 |
| Saavedra, B | 1 |
| Mambuque, E | 1 |
| Gomes, N | 1 |
| Nguenha, D | 1 |
| Mabunda, R | 1 |
| Faife, L | 1 |
| Langa, R | 1 |
| Munguambe, S | 1 |
| Manjate, F | 1 |
| Cossa, A | 1 |
| Scott, L | 3 |
| García-Basteiro, AL | 1 |
| Penn-Nicholson, A | 1 |
| Georghiou, SB | 3 |
| Ciobanu, N | 1 |
| Kazi, M | 1 |
| Bhalla, M | 5 |
| David, A | 2 |
| Conradie, F | 1 |
| Ruhwald, M | 2 |
| Crudu, V | 3 |
| Rodrigues, C | 2 |
| Myneedu, VP | 4 |
| Denkinger, CM | 5 |
| Schumacher, SG | 6 |
| Sağıroğlu, P | 1 |
| Atalay, MA | 1 |
| Khurana, P | 1 |
| Saigal, K | 1 |
| Ghosh, A | 1 |
| Gliddon, HD | 1 |
| Frampton, D | 1 |
| Munsamy, V | 1 |
| Heaney, J | 1 |
| Pataillot-Meakin, T | 1 |
| Nastouli, E | 1 |
| Pym, AS | 1 |
| Steyn, AJC | 1 |
| Pillay, D | 1 |
| McKendry, RA | 1 |
| Nolt, D | 1 |
| Starke, JR | 1 |
| Habiburrahman, M | 1 |
| Ariq, H | 1 |
| Handayani, RRD | 1 |
| Anthwal, D | 3 |
| Jamwal, S | 1 |
| Gupta, RK | 3 |
| Singhal, R | 2 |
| Verma, AK | 1 |
| Sarin, R | 1 |
| Choudhary, S | 2 |
| Tyagi, JS | 3 |
| Haldar, S | 3 |
| Benaissa, E | 1 |
| Benlahlou, Y | 1 |
| Bssaibis, F | 1 |
| Maleb, A | 1 |
| Elouennass, M | 1 |
| Soltobekova, N | 1 |
| Kozukeev, T | 1 |
| Yiehdego, G | 1 |
| Labib, F | 1 |
| Hovhannesyan, A | 1 |
| Rossi, R | 1 |
| Aono, A | 3 |
| Murase, Y | 1 |
| Minegishi, M | 1 |
| Ohtawa, S | 1 |
| Yano, M | 1 |
| Chikamatsu, K | 3 |
| Shimomura, Y | 1 |
| Hosoya, M | 1 |
| Igarashi, Y | 2 |
| Morishige, Y | 1 |
| Yamada, H | 3 |
| Takaki, A | 2 |
| Togashi, K | 1 |
| Hiura, M | 1 |
| Mitarai, S | 4 |
| Vogensen, VB | 1 |
| Anthony, RM | 1 |
| Kerstjens, HAM | 1 |
| Tiberi, S | 2 |
| de Steenwinkel, JEM | 1 |
| Akkerman, OW | 1 |
| Tavares-Júnior, JWL | 1 |
| Teles Júnior, JN | 1 |
| Magalhães, SC | 1 |
| Cavalcante, TT | 1 |
| Coimbra, PPA | 1 |
| Luiz, RDSS | 1 |
| Pillay, S | 2 |
| Steingart, KR | 2 |
| Davies, GR | 1 |
| Chaplin, M | 1 |
| De Vos, M | 4 |
| Warren, R | 1 |
| Theron, G | 3 |
| Sharma, K | 2 |
| Sharma, M | 4 |
| Sharma, A | 2 |
| Dhillon, MS | 1 |
| Derendinger, B | 2 |
| Streicher, EM | 1 |
| Dolby, T | 2 |
| Scott, LA | 1 |
| Steinhobel, AD | 1 |
| Warren, RM | 3 |
| Lin, M | 1 |
| Chen, YW | 1 |
| Li, YR | 1 |
| Long, LJ | 1 |
| Qi, LY | 1 |
| Cui, TT | 1 |
| Wu, SY | 1 |
| Lin, JY | 1 |
| Wu, T | 1 |
| Yang, YC | 1 |
| Yuan, WH | 1 |
| Wu, GY | 1 |
| Lan, QW | 1 |
| Liu, JQ | 1 |
| Li, YP | 1 |
| Yu, ZY | 1 |
| Guo, XG | 1 |
| da Silva, P | 1 |
| Trollip, A | 1 |
| Schumacher, S | 1 |
| Stevens, W | 1 |
| Sharma, V | 1 |
| Parmar, UPS | 1 |
| Samanta, J | 1 |
| Kochhar, R | 1 |
| Sinha, SK | 1 |
| Armstrong, D | 2 |
| Fisher, S | 1 |
| Totten, M | 1 |
| Parrish, N | 1 |
| Zhang, S | 1 |
| Chen, X | 4 |
| Lin, Z | 1 |
| Tan, Y | 1 |
| Liang, B | 1 |
| Pan, Y | 1 |
| Huang, M | 1 |
| Su, B | 1 |
| Hu, X | 1 |
| Xu, Y | 2 |
| Li, Q | 3 |
| Rajendran, P | 1 |
| Padmapriyadarsini, C | 1 |
| Nair, S | 1 |
| Sivakumar, S | 1 |
| Wang, Q | 2 |
| Modongo, C | 1 |
| Allender, C | 1 |
| Engelthaler, DM | 1 |
| Zetola, NM | 1 |
| Shin, SS | 2 |
| Salim, S | 1 |
| Zaman, G | 4 |
| Younis, S | 1 |
| Hussain, W | 2 |
| Khurshid, U | 1 |
| Khadim, MT | 3 |
| Shah, M | 1 |
| Paradis, S | 1 |
| Betz, J | 1 |
| Beylis, N | 3 |
| Bharadwaj, R | 1 |
| Caceres, T | 1 |
| Gotuzzo, E | 1 |
| Joloba, M | 2 |
| Mave, V | 1 |
| Nakiyingi, L | 1 |
| Nicol, MP | 1 |
| Pradhan, N | 1 |
| King, B | 1 |
| Knecht, D | 1 |
| Maus, CE | 1 |
| Cooper, CK | 1 |
| Dorman, SE | 3 |
| Manabe, YC | 1 |
| Shibabaw, A | 1 |
| Gelaw, B | 1 |
| Kelley, HV | 1 |
| Tesfaye, E | 1 |
| Balada-Llasat, JM | 1 |
| Evans, CA | 2 |
| Torrelles, JB | 1 |
| Wang, SH | 1 |
| Tessema, B | 2 |
| Barcellos, RB | 2 |
| de Almeida, IN | 2 |
| da Silva, EC | 1 |
| Gomes, HM | 1 |
| de Assis Figueredo, LJ | 1 |
| Halon, ML | 1 |
| Dalla Costa, ER | 2 |
| Dos Santos, ÍR | 1 |
| Vater, MC | 1 |
| Alves, S | 1 |
| da Silva Carvalho, W | 1 |
| Suffys, P | 1 |
| Sola, C | 2 |
| de Miranda, SS | 2 |
| Rossetti, ML | 1 |
| Kritski, A | 1 |
| Wu, L | 1 |
| Ye, Z | 1 |
| Liu, H | 1 |
| Guo, H | 1 |
| Lin, J | 1 |
| Zheng, L | 1 |
| Chu, N | 1 |
| Liu, X | 5 |
| Ciesielczuk, H | 1 |
| Kouvas, N | 1 |
| North, N | 1 |
| Buchanan, R | 1 |
| Chumpa, N | 1 |
| Kawkitinarong, K | 1 |
| Rotcheewaphan, S | 1 |
| Sawatpanich, A | 1 |
| Petsong, S | 1 |
| Tumwasorn, S | 1 |
| Suwanpimolkul, G | 1 |
| Sethi, S | 2 |
| Agarwal, P | 1 |
| Khaneja, R | 1 |
| Kumar, N | 2 |
| Chandna, J | 1 |
| Aggarwal, AN | 1 |
| Yadav, R | 2 |
| Wan, L | 1 |
| Guo, Q | 1 |
| Wei, JH | 1 |
| Liu, HC | 1 |
| Li, MC | 1 |
| Jiang, Y | 1 |
| Zhao, LL | 1 |
| Zhao, XQ | 1 |
| Liu, ZG | 1 |
| Wan, KL | 1 |
| Li, GL | 1 |
| Guan, CX | 1 |
| Bello, GL | 1 |
| Morais, FCL | 1 |
| de Jesus, SP | 1 |
| Wolf, JM | 1 |
| Gehlen, M | 1 |
| Figueiredo, LJA | 1 |
| Soares, TDS | 1 |
| Rossetti, MLR | 1 |
| Bisognin, F | 1 |
| Lombardi, G | 1 |
| Finelli, C | 1 |
| Re, MC | 1 |
| Dal Monte, P | 1 |
| Kohli, M | 1 |
| MacLean, E | 1 |
| Pai, M | 4 |
| Kodera, T | 1 |
| Yamaguchi, T | 1 |
| Fukushima, Y | 1 |
| Kobayashi, K | 1 |
| Takarada, Y | 1 |
| Chizimu, JY | 1 |
| Nakajima, C | 1 |
| Solo, ES | 1 |
| Lungu, PS | 1 |
| Kawase, M | 1 |
| Suzuki, Y | 1 |
| Klaos, K | 1 |
| Agejeva, A | 1 |
| Kummik, T | 2 |
| Laks, S | 1 |
| Remets, O | 1 |
| Sasi, S | 1 |
| Tann, A | 1 |
| Viiklepp, P | 1 |
| Altraja, A | 1 |
| Svensson, E | 1 |
| Folkvardsen, DB | 1 |
| Rasmussen, EM | 1 |
| Lillebaek, T | 1 |
| Lin, D | 1 |
| Wang, X | 1 |
| Li, Y | 4 |
| Wang, W | 2 |
| Yu, X | 2 |
| Lin, B | 2 |
| Chen, Y | 2 |
| Lei, C | 1 |
| Zhang, X | 2 |
| Huang, J | 1 |
| Yang, W | 2 |
| Zhou, J | 1 |
| Zeng, J | 1 |
| Dippenaar, A | 1 |
| van Helden, PD | 1 |
| Mao, L | 1 |
| LaCourse, SM | 1 |
| Kim, S | 2 |
| Liu, C | 1 |
| Ning, B | 1 |
| Bao, D | 1 |
| Fan, J | 1 |
| Lyon, CJ | 1 |
| Sun, Z | 2 |
| Nachman, S | 1 |
| Mitchell, CD | 1 |
| Hu, TY | 1 |
| Bhatnagar, S | 1 |
| Havumaki, J | 2 |
| Hillemann, D | 4 |
| Ismail, N | 3 |
| Omar, SV | 3 |
| Boehme, C | 2 |
| Meaza, A | 1 |
| Kebede, A | 2 |
| Yaregal, Z | 1 |
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| Yenew, B | 2 |
| Diriba, G | 1 |
| Molalign, H | 1 |
| Tadesse, M | 1 |
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| Getahun, M | 1 |
| Desta, K | 1 |
| Chen, J | 2 |
| Peng, P | 1 |
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| Chen, L | 2 |
| Rao, Y | 1 |
| Abanda, NN | 1 |
| Djieugoué, JY | 1 |
| Lim, E | 1 |
| Pefura-Yone, EW | 1 |
| Mbacham, WF | 1 |
| Vernet, G | 1 |
| Penlap, VM | 1 |
| Eyangoh, SI | 1 |
| Taylor, DW | 1 |
| Leke, RGF | 1 |
| Kwak, M | 1 |
| Lee, WK | 1 |
| Lim, YJ | 1 |
| Lee, SH | 2 |
| Ryoo, S | 1 |
| Tam, KK | 1 |
| Leung, KS | 1 |
| To, SW | 1 |
| Siu, GK | 2 |
| Lau, TC | 1 |
| Shek, VC | 1 |
| Tse, CW | 1 |
| Wong, SS | 1 |
| Ho, PL | 1 |
| Yam, WC | 2 |
| Bonnet, M | 1 |
| Kyakwera, C | 1 |
| Kyomugasho, N | 1 |
| Atwine, D | 1 |
| Mugabe, F | 1 |
| Nansumba, M | 1 |
| Ii, YB | 1 |
| Mwanga-Amumpaire, J | 1 |
| Kiwanuka, J | 1 |
| Xie, YL | 1 |
| Chakravorty, S | 2 |
| Armstrong, DT | 1 |
| Hall, SL | 1 |
| Via, LE | 4 |
| Song, T | 1 |
| Yuan, X | 2 |
| Mo, X | 1 |
| Zhu, H | 1 |
| Lee, M | 2 |
| Lee, J | 2 |
| Smith, LE | 2 |
| Chen, RY | 1 |
| Joh, JS | 1 |
| Cho, Y | 1 |
| Ruan, X | 2 |
| Liang, L | 1 |
| Dharan, N | 1 |
| Cho, SN | 2 |
| Barry, CE | 5 |
| Ellner, JJ | 1 |
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| Yi, L | 1 |
| Chavalertsakul, K | 1 |
| Boonsarngsuk, V | 1 |
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| Ameni, G | 2 |
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| Nikolayevskyy, V | 2 |
| Casali, N | 1 |
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| Patel, B | 1 |
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| Drobniewski, F | 2 |
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| Tayyab, N | 1 |
| Satti, L | 3 |
| Ikram, A | 3 |
| Birungi, FM | 1 |
| van Wyk, B | 1 |
| Uwimana, J | 1 |
| Ntaganira, J | 1 |
| Graham, SM | 1 |
| Macías, A | 1 |
| Sánchez-Montalvá, A | 1 |
| Salvador, F | 1 |
| Villar, A | 1 |
| Tórtola, T | 1 |
| Saborit, N | 1 |
| Molina, I | 1 |
| Xu, L | 1 |
| Sun, YX | 1 |
| Zhan, SY | 1 |
| Amini, S | 1 |
| Hoffner, S | 6 |
| Allahyar Torkaman, MR | 1 |
| Hamzehloo, G | 1 |
| Nasiri, MJ | 1 |
| Salehi, M | 1 |
| Sami Kashkooli, G | 1 |
| Shahraki, MS | 1 |
| Mohsenpoor, M | 1 |
| Soleimanpour, S | 1 |
| Mir, R | 1 |
| Romanowski, K | 1 |
| Campbell, JR | 1 |
| Oxlade, O | 2 |
| Fregonese, F | 1 |
| Menzies, D | 3 |
| Johnston, JC | 1 |
| Luo, J | 2 |
| Luo, M | 2 |
| Li, J | 2 |
| Yu, J | 1 |
| Yang, H | 2 |
| Yi, X | 1 |
| Wei, H | 1 |
| Brandao, AP | 1 |
| Pinhata, JMW | 1 |
| Oliveira, RS | 1 |
| Galesi, VMN | 1 |
| Caiaffa-Filho, HH | 1 |
| Ferrazoli, L | 1 |
| Hussain, A | 1 |
| Timire, C | 1 |
| Metcalfe, JZ | 1 |
| Chirenda, J | 1 |
| Scholten, JN | 1 |
| Manyame-Murwira, B | 1 |
| Ngwenya, M | 1 |
| Matambo, R | 1 |
| Charambira, K | 1 |
| Mutunzi, H | 1 |
| Kalisvaart, N | 1 |
| Sandy, C | 1 |
| Pina, JM | 1 |
| Clotet, L | 1 |
| Ferrer, A | 1 |
| Sala, MR | 1 |
| Garrido, P | 1 |
| Salleras, L | 1 |
| Domínguez, A | 1 |
| Munkhdelger, J | 1 |
| Wang, HY | 1 |
| Choi, Y | 1 |
| Wairagu, PM | 1 |
| Lee, D | 1 |
| Park, S | 1 |
| Jeon, BY | 1 |
| Lee, H | 1 |
| Park, KH | 1 |
| Law, S | 1 |
| Benedetti, A | 1 |
| Schwartzman, K | 1 |
| Gomgnimbou, MK | 1 |
| Hernández-Neuta, I | 2 |
| Panaiotov, S | 2 |
| Bachiyska, E | 1 |
| Palomino, JC | 7 |
| Martin, A | 8 |
| del Portillo, P | 2 |
| Refregier, G | 1 |
| Yadav, RN | 1 |
| Singh, BK | 1 |
| Sharma, SK | 1 |
| Sharma, R | 2 |
| Soneja, M | 1 |
| Sreenivas, V | 1 |
| Hanif, M | 1 |
| Kumar, A | 1 |
| Sachdeva, KS | 1 |
| Paramasivan, CN | 1 |
| Vollepore, B | 1 |
| Thakur, R | 1 |
| Raizada, N | 1 |
| Arora, SK | 1 |
| Sinha, S | 2 |
| Coronel, J | 4 |
| Roper, MH | 1 |
| Herrera, C | 1 |
| Bonilla, C | 2 |
| Jave, O | 1 |
| Gianella, C | 1 |
| Sabogal, I | 1 |
| Huancaré, V | 1 |
| Leo, E | 1 |
| Tyas, A | 1 |
| Mendoza-Ticona, A | 1 |
| Caviedes, L | 4 |
| Moore, DA | 4 |
| Cho, E | 1 |
| Shamputa, IC | 1 |
| Kwak, HK | 1 |
| Hwang, S | 1 |
| Jeon, D | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicentre Clinical Trial to Assess the Performance of the Xpert MTB/XDR Assay for INH- and Second-line Resistance Detection[NCT03728725] | 710 participants (Actual) | Observational | 2019-07-11 | Completed | |||
| Culture Free Diagnosis and Follow-up of Multidrug Resistant Tuberculosis Patients[NCT03303963] | 3,356 participants (Actual) | Observational | 2017-05-04 | Completed | |||
| Feasibility and Accuracy of a Novel Xpert Cartridge for Rapid Molecular Detection of Drug Resistant Mycobacterium Tuberculosis in Sputum[NCT02251327] | 401 participants (Actual) | Observational | 2014-06-04 | Completed | |||
| A Natural History Study of Multidrug-Resistant Tuberculosis Strains and Host Susceptibility Genes in Korean Patients With Pulmonary Tuberculosis[NCT00341601] | 777 participants (Actual) | Observational | 2005-01-03 | Completed | |||
| TB Screening Improves Preventive Therapy Uptake Trial[NCT04557176] | 1,719 participants (Actual) | Interventional | 2020-11-16 | Active, not recruiting | |||
| URBAN ARCH (3/5) Uganda Cohort TB Preventive Therapy for HIV-infected Alcohol Users in Uganda: an Evaluation of Safety Tolerability and Adherence[NCT03302299] | Phase 4 | 302 participants (Actual) | Interventional | 2017-04-07 | Completed | ||
| Study of Adherence to Antihypertensive Drugs and Statins in the Population of Subjects With Hypertension Followed at SIIA Centers, Using an Innovative Monitoring Based on Hair Analysis[NCT05347823] | 200 participants (Anticipated) | Observational | 2022-05-15 | Not yet recruiting | |||
| Global Consortium for Drug-resistant Tuberculosis Diagnostics[NCT02170441] | 1,128 participants (Actual) | Observational | 2012-04-30 | Completed | |||
| Feasibility, Accuracy, and Effect of Point-of-care Xpert MTB/RIF Ultra and Xpert MTB/RIF Ultra Testing in Patients Suspected of Having TB: a Randomised Controlled Trial[NCT03356925] | 1,549 participants (Actual) | Interventional | 2018-02-06 | Completed | |||
| A Randomized, Placebo-Controlled Study of Limited vs. Continuous Isoniazid Tuberculosis Preventive Therapy in HIV-infected Persons in Botswana[NCT00164281] | Phase 4 | 2,000 participants (Actual) | Interventional | 2004-11-30 | Completed | ||
| Behavior Change and Digital Health Interventions for Improved TB Treatment Outcomes: a RCT[NCT04119375] | 16,146 participants (Actual) | Interventional | 2018-04-13 | Completed | |||
| PROvide MIner-friendly SErvices for Integrated TB/HIV Care in Lesotho Study (PROMISE Study)[NCT03537872] | 248 participants (Actual) | Interventional | 2018-03-13 | Completed | |||
| TB Treatment Support Tools: Refinement and Evaluation of an Interactive Mobile App and Direct Adherence Monitoring on TB Treatment Outcomes[NCT04221789] | 555 participants (Actual) | Interventional | 2020-11-17 | Active, not recruiting | |||
| NexGen EBA Radiologic and Immunologic Biomarkers of Sterilizing Drug Activity in Tuberculosis[NCT02371681] | Phase 2 | 262 participants (Actual) | Interventional | 2015-02-25 | Completed | ||
| Pharmacokinetics and Pharmacodynamics of High Versus Standard Dose Rifampicin in Patients With Pulmonary Tuberculosis in the Kilimanjaro Region, Tanzania.[NCT00760149] | Phase 2 | 150 participants (Actual) | Interventional | 2010-07-31 | Completed | ||
| Enhanced TB Screening to Determine the Prevalence and Incidence of TB in a Cohort of HIV Clinic Patients in Lusaka, Zambia[NCT02043067] | 400 participants (Actual) | Observational | 2011-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Safety will be assessed by the occurrence of a Grade 3/4 hepatotoxicity at any time during the assigned treatment period. (NCT03302299)
Timeframe: Hepatotoxicity occurring during the six month course (180 pills) of isoniazid (INH), which may be taken over a maximum of 9 months.
| Intervention | percent (Number) |
|---|---|
| INH and Vitamin B6 | 8.3 |
Lack of tolerability will be defined as any isoniazid (INH) treatment discontinuation prior to completion of the prescribed course (6 months of INH taken over a maximum period of 9 months) due to side effects or alanine transaminase (ALT)/aspartate transaminase (AST) elevations. (NCT03302299)
Timeframe: Six month course (180 pills) of isoniazid (INH), which may be taken over a maximum of 9 months.
| Intervention | Participants (Count of Participants) |
|---|---|
| INH and Vitamin B6 | 32 |
Alanine transaminase (ALT) or aspartate transaminase (AST) elevations (>2x the upper limit of normal) at study screening (NCT03302299)
Timeframe: Study screening visit
| Intervention | Participants (Count of Participants) |
|---|---|
| Study Screening | 80 |
Latent tuberculosis assessed at screening via tuberculin skin testing (TST). A TST induration >=5mm was considered positive for latent tuberculosis. (NCT03302299)
Timeframe: Study screening visit
| Intervention | Participants (Count of Participants) |
|---|---|
| Study Screening | 308 |
INH concentration in hair (pmol/mg) will be measured at 3- and 6- months during INH therapy. (NCT03302299)
Timeframe: Measured at 3- and 6- months after INH initiation
| Intervention | pmol/mg (Median) | |
|---|---|---|
| at 3 months | at 6 months | |
| INH and Vitamin B6 | 36.0 | 37.8 |
Suboptimal INH adherence was defined as <90% of days with at least 1 electronic medication management (EMM) pill cap opening in the previous 90 days, at 3- and 6-months. (NCT03302299)
Timeframe: Adherence will be measured over the 6 months on INH or until INH discontinuation (whichever is shorter)
| Intervention | percentage of participants (Number) | |
|---|---|---|
| at 3 months | at 6 months | |
| INH and Vitamin B6 | 31.3 | 43.9 |
"Participants were asked In the past 30 days, how many days in total have you not taken your pill? and were presented with a visual analog scale (VAS) to indicate the percentage of INH taken in the past 30 days. We converted the VAS percentage into number of days out of 30 to match the first question. Our final self-report measure was the minimum number of the 2 self-reported measurements." (NCT03302299)
Timeframe: Self-reported INH medication adherence via VAS will be measured 3- and 6- months after starting INH
| Intervention | days (Median) | |
|---|---|---|
| at 3 months | at 6 months | |
| INH and Vitamin B6 | 30 | 30 |
The Self Rating Single Item (SRSI) adherence scale asks participants to rate their ability to take their medications as prescribed over the past 30 days. Participants reporting INH use in the prior 30 days at the 3- or 6-month interview are included here, and reported their INH adherence in the prior 30 days as excellent, very good, good, fair, poor, or very poor. (NCT03302299)
Timeframe: Self-reported INH medication adherence via SRSI will be measured 3- and 6- months after starting INH
| Intervention | Participants (Count of Participants) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| At 3 months72558043 | At 6 months72558043 | |||||||||||
| Excellent | Very good | Good | Fair | Poor | Very poor | |||||||
| INH and Vitamin B6 | 160 | |||||||||||
| INH and Vitamin B6 | 79 | |||||||||||
| INH and Vitamin B6 | 38 | |||||||||||
| INH and Vitamin B6 | 2 | |||||||||||
| INH and Vitamin B6 | 124 | |||||||||||
| INH and Vitamin B6 | 90 | |||||||||||
| INH and Vitamin B6 | 41 | |||||||||||
| INH and Vitamin B6 | 4 | |||||||||||
| INH and Vitamin B6 | 0 | |||||||||||
| INH and Vitamin B6 | 1 | |||||||||||
14 reviews available for isoniazid and Sensitivity and Specificity
| Article | Year |
|---|---|
Combining LAMP and Au-Nanoprobe to detect INH-RIF resistance accurately in tuberculosis: an evidence-based review.
Topics: Antibiotics, Antitubercular; DNA, Bacterial; Humans; Isoniazid; Molecular Diagnostic Techniques; Nuc | 2021 |
Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and amikacin.
Topics: Adult; Amikacin; Antibiotics, Antitubercular; Drug Resistance, Bacterial; Ethionamide; Fluoroquinolo | 2022 |
Systematic evaluation of line probe assays for the diagnosis of tuberculosis and drug-resistant tuberculosis.
Topics: Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Microbial Sensiti | 2022 |
Diagnostic accuracy of centralised assays for TB detection and detection of resistance to rifampicin and isoniazid: a systematic review and meta-analysis.
Topics: Antibiotics, Antitubercular; Cross-Sectional Studies; Drug Resistance, Bacterial; Humans; Isoniazid; | 2021 |
Systematic review and meta-analysis of the nitrate reductase assay for drug susceptibility testing of Mycobacterium tuberculosis and the detection limits in liquid medium.
Topics: Antitubercular Agents; Colorimetry; Humans; Isoniazid; Limit of Detection; Microbial Sensitivity Tes | 2017 |
[Diagnostic accuracy of line probe assays for drug-resistant tuberculosis: a Meta-analysis].
Topics: Antitubercular Agents; Biological Assay; China; Humans; Isoniazid; Microbial Sensitivity Tests; Myco | 2018 |
Accuracy of line probe assays for the diagnosis of pulmonary and multidrug-resistant tuberculosis: a systematic review and meta-analysis.
Topics: Antitubercular Agents; DNA Probes; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Microbia | 2017 |
GenoType MTBDR assays for the diagnosis of multidrug-resistant tuberculosis: a meta-analysis.
Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Bacterial; Humans; Isoniazid; Microbial | 2008 |
Direct susceptibility testing for multi drug resistant tuberculosis: a meta-analysis.
Topics: Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; ROC Curve; Sen | 2009 |
Recent advances in the laboratory detection of Mycobacterium tuberculosis complex and drug resistance.
Topics: Antitubercular Agents; Bacteriological Techniques; Drug Resistance, Bacterial; Humans; Isoniazid; Mo | 2011 |
Clinical practice. Latent tuberculosis infection.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Male; Practice Guideline | 2002 |
[Modern diagnosis of tuberculosis].
Topics: Adenosine Deaminase; Antibiotics, Antitubercular; Antitubercular Agents; Bacteriological Techniques; | 2006 |
The nitrate reductase assay for the rapid detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis.
Topics: Anti-Bacterial Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; N | 2008 |
Outpatient management of tuberculosis.
Topics: Algorithms; Ambulatory Care; Antitubercular Agents; Drug Administration Schedule; Drug Interactions; | 1996 |
2 trials available for isoniazid and Sensitivity and Specificity
| Article | Year |
|---|---|
Evaluation of a serum-based antigen test for tuberculosis in HIV-exposed infants: a diagnostic accuracy study.
Topics: Antigens, Bacterial; Child; HIV Infections; Humans; Infant; Isoniazid; Mycobacterium tuberculosis; S | 2021 |
Substandard tuberculosis drugs on the global market and their simple detection.
Topics: Antitubercular Agents; Asia; Chromatography, Thin Layer; Colombia; Drug Combinations; Europe, Easter | 2001 |
326 other studies available for isoniazid and Sensitivity and Specificity
| Article | Year |
|---|---|
Prevalence of and molecular basis for tuberculosis drug resistance in the Republic of Georgia: validation of a QIAplex system for detection of drug resistance-related mutations.
Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Ethambutol; Georgia | 2008 |
Selection of mutations to detect multidrug-resistant Mycobacterium tuberculosis strains in Shanghai, China.
Topics: Antitubercular Agents; Bacterial Proteins; China; Cohort Studies; Culture Media; Drug Resistance, Mu | 2010 |
Analysis of the application of a gene chip method for detecting Mycobacterium tuberculosis drug resistance in clinical specimens: a retrospective study.
Topics: Antibiotics, Antitubercular; Bacterial Proteins; Catalase; Codon; DNA-Directed RNA Polymerases; Drug | 2021 |
Diagnostic performance of the Abbott RealTime MTB assay for tuberculosis diagnosis in people living with HIV.
Topics: Adult; DNA, Bacterial; Drug Resistance, Bacterial; Female; HIV Infections; Humans; Isoniazid; Male; | 2021 |
Detection of isoniazid, fluoroquinolone, ethionamide, amikacin, kanamycin, and capreomycin resistance by the Xpert MTB/XDR assay: a cross-sectional multicentre diagnostic accuracy study.
Topics: Adult; Amikacin; Australia; Capreomycin; Cross-Sectional Studies; Drug Resistance, Bacterial; Ethion | 2022 |
Evaluation of the performance of the BD MAX MDR-TB test in the diagnosis of
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; R | 2021 |
Drug resistance pattern and mutation pattern in pediatric tuberculosis: Study from north India.
Topics: Antitubercular Agents; Child; Drug Resistance; Humans; India; Isoniazid; Microbial Sensitivity Tests | 2021 |
A Rapid Drug Resistance Genotyping Workflow for Mycobacterium tuberculosis, Using Targeted Isothermal Amplification and Nanopore Sequencing.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Genotype; Humans; Isoniazid; Mycobacterium tuberc | 2021 |
Tuberculosis Infection in Children and Adolescents: Testing and Treatment.
Topics: Adolescent; Age Factors; Antitubercular Agents; BCG Vaccine; Child; Child, Preschool; Cross Reaction | 2021 |
Direct Molecular Detection of Drug-Resistant Tuberculosis from Transported Bio-Safe Dried Sputum on Filter-Paper.
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; S | 2022 |
Evaluation of a Molecular Test for Detection of Mycobacterium tuberculosis Isolates Resistant to Rifampicin and Isoniazid.
Topics: Antitubercular Agents; Genotype; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacte | 2022 |
Time to start of tuberculosis treatment in penitentiary system of Kyrgyz Republic: A retrospective cohort study.
Topics: Humans; Isoniazid; Kyrgyzstan; Mycobacterium tuberculosis; Prisons; Retrospective Studies; Rifampin; | 2022 |
Clinical evaluation of the cobas® MTB-RIF/INH reagent and the cobas® 6800 for the detection of isoniazid and rifampicin resistance.
Topics: Humans; Indicators and Reagents; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; | 2022 |
The case for expanding worldwide access to point of care molecular drug susceptibility testing for isoniazid.
Topics: Drug Resistance, Bacterial; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculos | 2022 |
Parinaud syndrome due to cofirmed neurotuberculosis in a lupus eritematosis systemic patient.
Topics: Ethambutol; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Ocular Motility Disorders; Sensit | 2023 |
Diagnosing osteo-articular tuberculosis and multidrug resistance using real-time polymerase chain reaction and high-resolution melt-curve analysis.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Microbial Sensitivit | 2023 |
Non-actionable Results, Accuracy, and Effect of First- and Second-line Line Probe Assays for Diagnosing Drug-Resistant Tuberculosis, Including on Smear-Negative Specimens, in a High-Volume Laboratory.
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; R | 2023 |
Feasibility, Ease-of-Use, and Operational Characteristics of World Health Organization-Recommended Moderate-Complexity Automated Nucleic Acid Amplification Tests for the Detection of Tuberculosis and Resistance to Rifampicin and Isoniazid.
Topics: Feasibility Studies; Humans; Isoniazid; Mycobacterium tuberculosis; Nucleic Acid Amplification Techn | 2023 |
MTBDRplus and MTBDRsl for simultaneous diagnosis of gastrointestinal tuberculosis and detection of first-line and second-line drug resistance.
Topics: Antitubercular Agents; Genotype; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuber | 2023 |
An analytic feasibility study of the BD MAX™ MDR-TB assay for testing of non-sputum specimens for detection of the Mycobacterium tuberculosis complex (MTBC) and isoniazid (INH) and rifampin (RIF) resistance.
Topics: Antitubercular Agents; Feasibility Studies; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobact | 2023 |
Quantification of Isoniazid-Heteroresistant Mycobacterium tuberculosis Using Droplet Digital PCR.
Topics: Antitubercular Agents; Bacterial Proteins; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; | 2023 |
Newer TB diagnostics: An update.
Topics: Antibiotics, Antitubercular; Drug Resistance, Bacterial; Humans; Isoniazid; Mycobacterium tuberculos | 2023 |
Direct Detection of Fluoroquinolone Resistance in Sputum Samples from Tuberculosis Patients by High Resolution Melt Curve Analysis.
Topics: Antitubercular Agents; Fluoroquinolones; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacteri | 2023 |
Utility of Targeted, Amplicon-Based Deep Sequencing To Detect Resistance to First-Line Tuberculosis Drugs in Botswana.
Topics: Adult; Antitubercular Agents; Botswana; Female; High-Throughput Nucleotide Sequencing; Humans; Isoni | 2019 |
Multiplex PCR for Rapid Diagnosis of Drug Resistant Mycobacterium Tuberculosis.
Topics: Antitubercular Agents; Cross-Sectional Studies; Drug Resistance, Bacterial; Ethambutol; Humans; Ison | 2019 |
Multicenter Study of the Accuracy of the BD MAX Multidrug-resistant Tuberculosis Assay for Detection of Mycobacterium tuberculosis Complex and Mutations Associated With Resistance to Rifampin and Isoniazid.
Topics: Adult; Drug Resistance, Bacterial; Female; Humans; India; Isoniazid; Male; Microbial Sensitivity Tes | 2020 |
MDR/XDR-TB Colour Test for drug susceptibility testing of Mycobacterium tuberculosis, Northwest Ethiopia.
Topics: Adolescent; Adult; Antitubercular Agents; Ciprofloxacin; Culture Media; Ethiopia; Extensively Drug-R | 2020 |
Multicenter evaluation of TB-SPRINT 59-Plex Beamedex®: accuracy and cost analysis.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; Costs and Cost Analysis; DNA-Directed RNA Polym | 2019 |
Rapid and highly sensitive quantification of the anti-tuberculosis agents isoniazid, ethambutol, pyrazinamide, rifampicin and rifabutin in human plasma by UPLC-MS/MS.
Topics: AIDS-Related Opportunistic Infections; Antitubercular Agents; Calibration; Chromatography, High Pres | 2020 |
Evaluation of the BD MAX™ MDR-TB assay in a real-world setting for the diagnosis of pulmonary and extra-pulmonary TB.
Topics: Antibiotics, Antitubercular; Drug Resistance, Bacterial; Female; Humans; Isoniazid; Male; Microbial | 2020 |
Evaluation of Anyplex™ II MTB/MDR kit's performance to rapidly detect isoniazid and rifampicin resistant Mycobacterium tuberculosis from various clinical specimens.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Microbial Sensitivit | 2020 |
Second-line Drug Resistance Characterization in
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Extensively Drug-Resistant | 2020 |
Accuracy of a reverse dot blot hybridization assay for simultaneous detection of the resistance of four anti-tuberculosis drugs in Mycobacterium tuberculosis isolated from China.
Topics: Antitubercular Agents; China; Drug Resistance, Bacterial; Ethambutol; Humans; Immunoblotting; Isonia | 2020 |
Rapid detection of Mycobacterium tuberculosis DNA and genetic markers for Isoniazid resistance in Ziehl-Neelsen stained slides.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Genetic Markers; Genotype; Humans | 2020 |
Simultaneous detection of Mycobacterium tuberculosis complex and resistance to Rifampicin and Isoniazid by MDR/MTB ELITe MGB® Kit for the diagnosis of tuberculosis.
Topics: Antibiotics, Antitubercular; Biopsy; Drug Resistance, Bacterial; Genotype; Humans; Isoniazid; Microb | 2020 |
Rapid and Simple Detection of Isoniazid-Resistant Mycobacterium tuberculosis Utilizing a DNA Chromatography-Based Technique.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; Chromatography; DNA, Bacterial; Humans; Isoniaz | 2021 |
A successful introduction to a non-expert setting of the thin-layer agar Colour Test as an indirect phenotypic drug susceptibility test for Mycobacterium tuberculosis.
Topics: Agar; Antitubercular Agents; Color; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mycobacter | 2021 |
Detection of Mycobacterium tuberculosis complex in pulmonary and extrapulmonary samples with the FluoroType MTBDR assay.
Topics: Antitubercular Agents; Bacterial Proteins; Humans; Isoniazid; Mutation; Mycobacterium tuberculosis; | 2021 |
Sputum microbiota as a potential diagnostic marker for multidrug-resistant tuberculosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; DNA, Bacterial; Female; Humans; Isoniazid; Male; Mic | 2021 |
Diagnostic accuracy of the FluoroType MTB and MTBDR VER 2.0 assays for the centralized high-throughput detection of Mycobacterium tuberculosis complex DNA and isoniazid and rifampicin resistance.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Isoniazid; Microbial Sens | 2021 |
Direct Detection of Rifampin and Isoniazid Resistance in Sputum Samples from Tuberculosis Patients by High-Resolution Melt Curve Analysis.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Fatty Acid Synthesis Inhibitors; | 2017 |
Comparative accuracy of the REBA MTB MDR and Hain MTBDRplus line probe assays for the detection of multidrug-resistant tuberculosis: A multicenter, non-inferiority study.
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Rifampin; Sensitivity and Spe | 2017 |
Evaluation of genotype MTBDRplus VER 2.0 line probe assay for the detection of MDR-TB in smear positive and negative sputum samples.
Topics: Adult; Antitubercular Agents; Bacterial Typing Techniques; Cross-Sectional Studies; Cytodiagnosis; E | 2017 |
Early detection of multidrug- and pre-extensively drug-resistant tuberculosis from smear-positive sputum by direct sequencing.
Topics: Amino Acid Substitution; Antitubercular Agents; Bacterial Proteins; China; Early Diagnosis; Extensiv | 2017 |
Diagnostic accuracy and usefulness of the Genotype MTBDRplus assay in diagnosing multidrug-resistant tuberculosis in Cameroon? a cross-sectional study.
Topics: Adult; Antitubercular Agents; Bacterial Proteins; Cameroon; Cross-Sectional Studies; Female; Genotyp | 2017 |
Direct detection of Mycobacterium tuberculosis and drug resistance in respiratory specimen using Abbott Realtime MTB detection and RIF/INH resistance assay.
Topics: Antibiotics, Antitubercular; Bacterial Proteins; DNA-Directed RNA Polymerases; High-Throughput Scree | 2017 |
Prospective cohort study of the feasibility and yield of household child tuberculosis contact screening in Uganda.
Topics: Algorithms; Antitubercular Agents; Child, Preschool; Cohort Studies; Contact Tracing; Cough; Feasibi | 2017 |
Evaluation of a Rapid Molecular Drug-Susceptibility Test for Tuberculosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoglycosides; Antitubercular Agents; China; DNA, Bact | 2017 |
Laboratory evaluation of the Anyplex™ II MTB/MDR and MTB/XDR tests based on multiplex real-time PCR and melting-temperature analysis to identify Mycobacterium tuberculosis and drug resistance.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resist | 2017 |
TB-PCR and drug resistance pattern in BALF in smear-negative active pulmonary TB.
Topics: Adult; Aged; Antitubercular Agents; Bronchoalveolar Lavage Fluid; Drug Resistance, Bacterial; Female | 2017 |
Evaluation of Whole-Genome Sequencing for Mycobacterial Species Identification and Drug Susceptibility Testing in a Clinical Setting: a Large-Scale Prospective Assessment of Performance against Line Probe Assays and Phenotyping.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Genome, Bacterial; Humans; Isoniazid; Molecular T | 2018 |
Performance of MTBDRplus assay in detecting multidrug resistant tuberculosis at hospital level.
Topics: Antitubercular Agents; Biological Assay; Drug Resistance, Bacterial; Ethiopia; Hospitals; Humans; Is | 2017 |
50 Years Ago in The Journal of Pediatrics: Isoniazid Prophylaxis in Tuberculin Reactors.
Topics: Child; History, 20th Century; Humans; Interferon-gamma Release Tests; Isoniazid; Pediatrics; Risk Fa | 2018 |
Evaluation of Nitrate Reductase Assay for Early Detection of Multi and Extensively Drug Resistance Tuberculosis in our Setup.
Topics: Amikacin; Antitubercular Agents; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Earl | 2018 |
Validation of the FluoroType MTBDR Assay for Detection of Rifampin and Isoniazid Resistance in Mycobacterium tuberculosis Complex Isolates.
Topics: Antitubercular Agents; Bacterial Proteins; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Gen | 2018 |
Experimental platform utilising melting curve technology for detection of mutations in Mycobacterium tuberculosis isolates.
Topics: Antitubercular Agents; Base Sequence; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Micro | 2018 |
New and Noteworthy in Tuberculosis Diagnostics and Treatment.
Topics: Adult; Antitubercular Agents; Female; HIV Infections; Humans; Isoniazid; Latent Tuberculosis; Male; | 2018 |
Direct Susceptibility Testing on MGIT 960 TB System: A Rapid Method for Detection of Drug Resistant Tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Female; Humans; Isoniazid; Male; Microb | 2018 |
Xpert MTB/RIF assay did not improve diagnosis of pulmonary tuberculosis among child contacts in Rwanda.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Bacteriological Techniques; Child; Child, Preschool; | 2018 |
Epidemiology and diagnosis of pleural tuberculosis in a low incidence country with high rate of immigrant population: A retrospective study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Drug Resistance, Multiple, Bacter | 2019 |
Direct drug susceptibility testing of Mycobacterium tuberculosis using the proportional method: A multicenter study.
Topics: Antitubercular Agents; Bacteriological Techniques; Drug Resistance, Multiple, Bacterial; Ethambutol; | 2019 |
The impact of improved detection and treatment of isoniazid resistant tuberculosis on prevalence of multi-drug resistant tuberculosis: A modelling study.
Topics: Antitubercular Agents; Decision Support Techniques; Drug Resistance, Bacterial; Humans; Isoniazid; M | 2019 |
Rapid direct drug susceptibility testing of
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; P | 2019 |
Speeding up the diagnosis of multidrug-resistant tuberculosis in a high-burden region with the use of a commercial line probe assay.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Child, Preschool; DNA, Bac | 2019 |
Evaluation of Thin Layer Agar 7H11 for Direct Susceptibility Testing of Mycobacterium Tuberculosis Complex against Second Line Anti Tuberculosis Drugs on Smear Positive Specimens.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antitubercular Agents; Bacteriolo | 2019 |
Prevalence of drug-resistant tuberculosis in Zimbabwe: A health facility-based cross-sectional survey.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Cross-Sectional Studies; Drug Resistance, Bac | 2019 |
Cost-effectiveness of rifampin for 4 months and isoniazid for 6 months in the treatment of tuberculosis infection.
Topics: Adolescent; Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cost-Benefit Analy | 2013 |
Identification of Mycobacterium species in FFPE granulomatous lymphadenitis tissue using REBA Myco-ID®.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Bacterial Typing Techniques; Child; Child, Pr | 2013 |
Comparing cost-effectiveness of standardised tuberculosis treatments given varying drug resistance.
Topics: Blindness; Cost-Benefit Analysis; Decision Trees; Drug Resistance, Bacterial; Ethambutol; Health Car | 2014 |
Tuberculosis-spoligo-rifampin-isoniazid typing: an all-in-one assay technique for surveillance and control of multidrug-resistant tuberculosis on Luminex devices.
Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Epidemiological Mon | 2013 |
Comparative evaluation of GenoType MTBDRplus line probe assay with solid culture method in early diagnosis of multidrug resistant tuberculosis (MDR-TB) at a tertiary care centre in India.
Topics: Adult; Antibiotics, Antitubercular; Bacterial Proteins; Catalase; Cross-Sectional Studies; Culture T | 2013 |
Validation of microscopic observation drug susceptibility testing for rapid, direct rifampicin and isoniazid drug susceptibility testing in patients receiving tuberculosis treatment.
Topics: Adolescent; Adult; Aged; Drug Resistance, Bacterial; Female; Humans; Isoniazid; Male; Microbial Sens | 2014 |
Utility of the REBA MTB-Rifa® assay for rapid detection of rifampicin resistant Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; DNA-Directed RNA Polymerases; Drug Resistance, Multiple, | 2013 |
Risk for tuberculosis in child contacts. Development and validation of a predictive score.
Topics: Antibiotic Prophylaxis; Antitubercular Agents; Child; Child, Preschool; Contact Tracing; Early Diagn | 2014 |
Point-of-care C-reactive protein testing to facilitate implementation of isoniazid preventive therapy for people living with HIV.
Topics: Adult; Antitubercular Agents; C-Reactive Protein; Clinical Laboratory Techniques; Cohort Studies; Fe | 2014 |
Rapid and accurate detection of rifampin and isoniazid-resistant Mycobacterium tuberculosis using an oligonucleotide array.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polymerases; Humans; Isoniazid | 2014 |
Rapid detection of multidrug-resistant Mycobacterium tuberculosis using the malachite green decolourisation assay.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Isoniazid; Microbial Sensitivity Tests; | 2013 |
Rolling circle amplification for direct detection of rpoB gene mutations in Mycobacterium tuberculosis isolates from clinical specimens.
Topics: Antitubercular Agents; Bacterial Proteins; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resist | 2014 |
Rapid detection of isoniazid resistance in Mycobacterium tuberculosis isolates by use of real-time-PCR-based melting curve analysis.
Topics: Bacterial Proteins; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Isoniazid; | 2014 |
A new rapid colourimetric method for testing Mycobacterium tuberculosis susceptibility to isoniazid and rifampicin: a crystal violet decolourisation assay.
Topics: Anti-Infective Agents; Antitubercular Agents; Cell Proliferation; Colorimetry; Developing Countries; | 2014 |
Optimization of the microscopic observation drug susceptibility assay for four first-line drugs using Mycobacterium tuberculosis reference strains and clinical isolates.
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tub | 2014 |
Reliability of Mycobacterial Growth Indicator Tube (MGIT) 960 for the detection of isoniazid resistance in a tuberculosis endemic setting.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Humans; Indicators and Reagents; Isoniazid; Micro | 2014 |
Detection of mutations associated with isoniazid resistance in multidrug-resistant Mycobacterium tuberculosis clinical isolates.
Topics: Adult; Aged; Antitubercular Agents; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Female; Ge | 2014 |
[Mycobacterium tuberculosis strains isolated from Van region four different sensitivity detection method antimycobacterial agents].
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tub | 2014 |
Cost-effectiveness of the Three I's for HIV/TB and ART to prevent TB among people living with HIV.
Topics: Algorithms; Antitubercular Agents; CD4 Lymphocyte Count; Cost-Benefit Analysis; Drug Resistance, Bac | 2014 |
False-positive rifampicin resistance on Xpert® MTB/RIF caused by a silent mutation in the rpoB gene.
Topics: Aged; Amikacin; Amino Acid Sequence; Antibiotics, Antitubercular; Bacterial Proteins; DNA-Directed R | 2014 |
A field evaluation of the Hardy TB MODS Kit™ for the rapid phenotypic diagnosis of tuberculosis and multi-drug resistant tuberculosis.
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; P | 2014 |
Rapid in vivo detection of isoniazid-sensitive Mycobacterium tuberculosis by breath test.
Topics: Animals; Bacterial Proteins; Breath Tests; Catalase; Isoniazid; Molecular Structure; Mycobacterium t | 2014 |
Evaluation of BACTEC MGIT 960 system for testing susceptibility of Mycobacterium tuberculosis to first-line drugs in China.
Topics: Antitubercular Agents; China; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacter | 2014 |
Selective determination of isoniazid using bentonite clay modified electrodes.
Topics: Aluminum Silicates; Bentonite; Catalysis; Clay; Electrochemical Techniques; Electrodes; Equipment De | 2015 |
Automated liquid culture system misses isoniazid heteroresistance in Mycobacterium tuberculosis isolates with mutations in the promoter region of the inhA gene.
Topics: Antitubercular Agents; Automation, Laboratory; Bacterial Proteins; False Negative Reactions; Humans; | 2015 |
Performance of Genotype MTBDRplus in the Detection of Resistance to Rifampicin and Isoniazid Among Clinical Mycobacteria Isolates in Ilorin, Nigeria.
Topics: Adult; Antitubercular Agents; Bacterial Proteins; DNA, Bacterial; Drug Resistance, Multiple, Bacteri | 2015 |
Xpert MTB/RIF and GenoType MTBDRplus assays for the rapid diagnosis of bone and joint tuberculosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Drug Resistance, Bacterial; Female; Genotype; Humans; Is | 2015 |
Evaluation of a novel line-probe assay for genotyping-based diagnosis of Mycobacterium tuberculosis in Thailand.
Topics: Antibiotics, Antitubercular; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Genotype; Hu | 2015 |
Role of a GenoType MTBDRplus line probe assay in early detection of multidrug-resistant tuberculosis at a Brazilian reference center.
Topics: Adult; Antitubercular Agents; Bacteriological Techniques; Brazil; DNA, Bacterial; Early Diagnosis; F | 2015 |
Comparison of Three Commercial Molecular Assays for Detection of Rifampin and Isoniazid Resistance among Mycobacterium tuberculosis Isolates in a High-HIV-Prevalence Setting.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Genotyping Techniques; HIV Infections; Humans; Is | 2015 |
Evaluation of GenoType MTBDRplus for the rapid detection of drug-resistant tuberculosis in Ghana.
Topics: Antitubercular Agents; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Ghana; Humans; | 2015 |
Prevalence and risk factors of drug-resistant tuberculosis in border provinces of Iran.
Topics: Adult; Aged; Bacterial Proteins; Catalase; Cross-Sectional Studies; DNA-Directed RNA Polymerases; Fe | 2015 |
Electrochemical sensor for Isoniazid based on the glassy carbon electrode modified with reduced graphene oxide-Au nanomaterials.
Topics: Biosensing Techniques; Carbon; Conductometry; Equipment Design; Equipment Failure Analysis; Glass; G | 2015 |
The concordance between phenotypic and genotypic M. tuberculosis drug susceptibility tests results: observational study.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polymerases; Genotype; Humans; | 2015 |
New Anyplex™ II MTB/MDR/XDR kit for detection of resistance mutations in M. tuberculosis cultures.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Genotype; Isoniazid; Microbial Sensitiv | 2015 |
The thin-layer agar method for direct phenotypic detection of multi- and extensively drug-resistant tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Isoniazid; Ka | 2015 |
Evaluation of GenoFlow DR-MTB Array Test for Detection of Rifampin and Isoniazid Resistance in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; Drug Resistance, Bacterial; Genotype; Genotypin | 2016 |
Rapid colorimetric pyrazinamide susceptibility testing of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Colorimetry; Drug Resistance, Bacterial; Isoniazid; Microbial Sensitivity Tes | 2016 |
Evaluation of the direct nitrate reductase assay for rapid detection of extensively drug-resistant tuberculosis.
Topics: Adult; Capreomycin; China; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tubercul | 2016 |
[Multicenter evaluation of the indirect nitrate reductase assay for the rapid detection of multidrug-resistant tuberculosis].
Topics: Antitubercular Agents; Colorimetry; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Microbi | 2016 |
Multicenter Noninferiority Evaluation of Hain GenoType MTBDRplus Version 2 and Nipro NTM+MDRTB Line Probe Assays for Detection of Rifampin and Isoniazid Resistance.
Topics: Antitubercular Agents; Cross-Sectional Studies; Drug Resistance, Bacterial; Genotyping Techniques; H | 2016 |
Quantifying Isoniazid Levels in Small Hair Samples: A Novel Method for Assessing Adherence during the Treatment of Latent and Active Tuberculosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Female; Gas Chromatography-Mass Spectrometry; Hair; | 2016 |
Comparison of Two Molecular Assays For Detecting Smear Negative Pulmonary Tuberculosis.
Topics: Antitubercular Agents; Bacteriological Techniques; Drug Resistance, Bacterial; Humans; Isoniazid; My | 2016 |
High-resolution melting analysis for molecular detection of multidrug resistance tuberculosis in Peruvian isolates.
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; P | 2016 |
Early detection of multidrug resistant (MDR) Mycobacterium tuberculosis in a single tube with in-house designed fluorescence resonance energy transfer (FRET) probes using real-time PCR.
Topics: Antitubercular Agents; DNA, Bacterial; Fluorescence Resonance Energy Transfer; Humans; Isoniazid; Mi | 2016 |
Rapid identification of the NAT2 genotype in tuberculosis patients by multicolor melting curve analysis.
Topics: Acetylation; Antitubercular Agents; Arylamine N-Acetyltransferase; China; Genotype; Humans; Isoniazi | 2016 |
Bacterial Loads Measured by the Xpert MTB/RIF Assay as Markers of Culture Conversion and Bacteriological Cure in Pulmonary TB.
Topics: Antitubercular Agents; Area Under Curve; Bacterial Load; Bacteriological Techniques; Biomarkers; Eth | 2016 |
[THE SENSITIVITY AND SPECIFICITY OF THE MOLECULAR GENOTYPE MTBDRPL US ASSAY (HAIN LIFESCIENCE GMBH, GERMANY) FOR RAPID DIAGNOSIS OF DRUG SUSCEPTIBILITY IN MYCOBACTERIUM TUBERCULOSIS ON SPUTUM SPECIMENS].
Topics: Antitubercular Agents; Bacterial Proteins; Bacterial Typing Techniques; Catalase; DNA-Directed RNA P | 2010 |
Shedding light on the performance of a pyrosequencing assay for drug-resistant tuberculosis diagnosis.
Topics: Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Genes, Bacterial; | 2016 |
Drug susceptibility testing of Mycobacterium tuberculosis by a nitrate reductase assay applied directly on microscopy-positive sputum samples.
Topics: Antitubercular Agents; Colorimetry; Cost-Benefit Analysis; Enzyme Assays; Humans; Isoniazid; Microbi | 2015 |
Pyrosequencing for rapid detection of tuberculosis resistance to Rifampicin and Isoniazid in Syrian and Lebanese clinical isolates.
Topics: Antitubercular Agents; Codon; DNA Mutational Analysis; Drug Resistance, Bacterial; Genes, Bacterial; | 2015 |
Cost-effectiveness analysis of microscopic observation drug susceptibility test versus Xpert MTB/Rif test for diagnosis of pulmonary tuberculosis in HIV patients in Uganda.
Topics: AIDS-Related Opportunistic Infections; Algorithms; Bacteriological Techniques; Cost-Benefit Analysis | 2016 |
Evaluation of the Abbott RealTime MTB and RealTime MTB INH/RIF Assays for Direct Detection of Mycobacterium tuberculosis Complex and Resistance Markers in Respiratory and Extrapulmonary Specimens.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Microbial Sensitivit | 2016 |
Detection of Isoniazid-, Fluoroquinolone-, Amikacin-, and Kanamycin-Resistant Tuberculosis in an Automated, Multiplexed 10-Color Assay Suitable for Point-of-Care Use.
Topics: Alleles; Amikacin; Antitubercular Agents; Automation, Laboratory; DNA, Bacterial; Extensively Drug-R | 2017 |
Role of real-time PCR for detection of tuberculosis and drug resistance directly from clinical samples.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance; Drug Resistance, Multiple, Bacterial; Humans | 2016 |
Analytical and clinical performance characteristics of the Abbott RealTime MTB RIF/INH Resistance, an assay for the detection of rifampicin and isoniazid resistant Mycobacterium tuberculosis in pulmonary specimens.
Topics: Antitubercular Agents; Colony Count, Microbial; Drug Resistance, Multiple, Bacterial; Humans; Isonia | 2016 |
Evaluation of the GenoType MTBDRplus assay for detection of rifampicin- and isoniazid-resistant Mycobacterium tuberculosis isolates in central Ethiopia.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Ethiopia; Genotyping Techniques; Humans; Isoniazi | 2016 |
Multicenter evaluation of crystal violet decolorization assay (CVDA) for rapid detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis.
Topics: Calorimetry; Developed Countries; Gentian Violet; Humans; Isoniazid; Microbial Sensitivity Tests; My | 2016 |
Performance of microscopic observation drug susceptibility for the rapid diagnosis of tuberculosis and detection of drug resistance in Bamako, Mali.
Topics: Adolescent; Adult; Antitubercular Agents; Cohort Studies; Early Diagnosis; Ethambutol; Female; Human | 2017 |
Is IPT more effective in high-burden settings? Modelling the effect of tuberculosis incidence on IPT impact.
Topics: Antitubercular Agents; Humans; Incidence; Isoniazid; Sensitivity and Specificity; Tuberculosis; Worl | 2017 |
Multidrug-resistant tuberculosis: rapid detection of resistance to rifampin and high or low levels of isoniazid in clinical specimens and isolates.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polymerases; Humans; Isoniazid | 2008 |
Prospective evaluation of pyrosequencing for the rapid detection of isoniazid and rifampin resistance in clinical Mycobacterium tuberculosis isolates.
Topics: Amino Acid Substitution; Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polym | 2009 |
GenoType MTBDRplus assay for molecular detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis strains and clinical samples.
Topics: Antitubercular Agents; Bacteriological Techniques; DNA, Bacterial; Drug Resistance; Genotype; German | 2008 |
M. tuberculosis Central Asian Strain 1 MDR isolates have more mutations in rpoB and katG genes compared with other genotypes.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; DNA Probes; DNA-Directed RNA Polymerases; Drug | 2009 |
Study of cloud point extraction and high-performance liquid chromatographic determination of isoniazid based on the formation of isonicotinylhydrazone.
Topics: Analytic Sample Preparation Methods; Antitubercular Agents; Benzaldehydes; Chromatography, High Pres | 2009 |
HPLC methods for determination of two novel thiosemicarbazone anti-cancer drugs (N4mT and Dp44mT) in plasma and their application to in vitro plasma stability of these agents.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Data Int | 2009 |
Development and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometry method for determination of isoniazid in human plasma.
Topics: Antitubercular Agents; Calibration; Chemical Phenomena; Chromatography, Liquid; Drug Stability; Huma | 2009 |
Genotypic detection of rifampicin and isoniazid resistant Mycobacterium tuberculosis strains by DNA sequencing: a randomized trial.
Topics: Adult; Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polymerases; DNA, Bacte | 2009 |
Microplate hybridization assay for detection of isoniazid resistance in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Biological Assay; Drug Resistance, Bacterial; Humans; Isoniazid; Microbial Se | 2009 |
Diagnosis of tuberculous uveitis: clinical application of an interferon-gamma release assay.
Topics: Adult; Antitubercular Agents; Area Under Curve; Drug Therapy, Combination; Enzyme-Linked Immunosorbe | 2009 |
A pyrosequencing method for molecular monitoring of regions in the inhA, ahpC and rpoB genes of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; DNA-Directed RNA Polymerases; DNA, Bacterial; Drug Resist | 2010 |
LC-MS/TOF and UHPLC-MS/MS study of in vivo fate of rifamycin isonicotinyl hydrazone formed on oral co-administration of rifampicin and isoniazid.
Topics: Administration, Oral; Animals; Antibiotics, Antitubercular; Calibration; Chromatography, High Pressu | 2010 |
Molecular detection of rifampin and isoniazid resistance to guide chronic TB patient management in Burkina Faso.
Topics: Antitubercular Agents; Burkina Faso; DNA Mutational Analysis; DNA, Bacterial; Humans; Isoniazid; Mic | 2009 |
Proficiency of drug susceptibility testing for Mycobacterium tuberculosis in Taiwan.
Topics: Antitubercular Agents; Bacteriological Techniques; Drug Resistance, Multiple, Bacterial; Ethambutol; | 2009 |
[Evaluation of the fully automated BACTEC MGIT 960 system for testing susceptibility of Mycobacterium tuberculosis to front line antituberculosis drugs and comparison with the radiometric BACTEC 460 TB method].
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tub | 2009 |
Evaluation of direct method of drug susceptibility testing of Mycobacterium tuberculosis to rifampicin and isoniazid by nitrate reductase assay in a national reference laboratory.
Topics: Antitubercular Agents; Colorimetry; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tu | 2010 |
Detection of isoniazid and rifampicin resistance by sequencing of katG, inhA, and rpoB genes in Korea.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polymerases; Drug Resistance, | 2009 |
Association of chest radiographic abnormalities with tuberculosis disease in asymptomatic HIV-infected adults.
Topics: Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Antitubercular Agents; Botswana; Fem | 2010 |
Tuberculous uveitis.
Topics: Antitubercular Agents; Area Under Curve; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assa | 2010 |
Au nanoparticle decorated silicate network for the amperometric sensing of isoniazid.
Topics: Antitubercular Agents; Electrochemistry; Gold; Hydrazines; Isoniazid; Linear Models; Metal Nanoparti | 2010 |
Rapid detection of rifampicin- and isoniazid-resistant Mycobacterium tuberculosis by high-resolution melting analysis.
Topics: Antitubercular Agents; Bacterial Proteins; DNA, Bacterial; Humans; Isoniazid; Microbial Sensitivity | 2010 |
Rapid screening of MDR-TB using molecular Line Probe Assay is feasible in Uganda.
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Molecular Diagnostic Techniqu | 2010 |
Microscopic observation drug susceptibility assay for tuberculosis screening before isoniazid preventive therapy in HIV-infected persons.
Topics: Adult; Antitubercular Agents; Bacterial Typing Techniques; Chi-Square Distribution; Drug Resistance, | 2010 |
Point-of-care Arkansas method for measuring adherence to treatment with isoniazid.
Topics: Adult; Antitubercular Agents; Brazil; Female; Humans; Isoniazid; Male; Medication Adherence; Sensiti | 2010 |
Point-of-care Arkansas method for measuring adherence to treatment with isoniazid.
Topics: Adult; Antitubercular Agents; Brazil; Female; Humans; Isoniazid; Male; Medication Adherence; Sensiti | 2010 |
Point-of-care Arkansas method for measuring adherence to treatment with isoniazid.
Topics: Adult; Antitubercular Agents; Brazil; Female; Humans; Isoniazid; Male; Medication Adherence; Sensiti | 2010 |
Point-of-care Arkansas method for measuring adherence to treatment with isoniazid.
Topics: Adult; Antitubercular Agents; Brazil; Female; Humans; Isoniazid; Male; Medication Adherence; Sensiti | 2010 |
Point-of-care Arkansas method for measuring adherence to treatment with isoniazid.
Topics: Adult; Antitubercular Agents; Brazil; Female; Humans; Isoniazid; Male; Medication Adherence; Sensiti | 2010 |
Point-of-care Arkansas method for measuring adherence to treatment with isoniazid.
Topics: Adult; Antitubercular Agents; Brazil; Female; Humans; Isoniazid; Male; Medication Adherence; Sensiti | 2010 |
Point-of-care Arkansas method for measuring adherence to treatment with isoniazid.
Topics: Adult; Antitubercular Agents; Brazil; Female; Humans; Isoniazid; Male; Medication Adherence; Sensiti | 2010 |
Point-of-care Arkansas method for measuring adherence to treatment with isoniazid.
Topics: Adult; Antitubercular Agents; Brazil; Female; Humans; Isoniazid; Male; Medication Adherence; Sensiti | 2010 |
Point-of-care Arkansas method for measuring adherence to treatment with isoniazid.
Topics: Adult; Antitubercular Agents; Brazil; Female; Humans; Isoniazid; Male; Medication Adherence; Sensiti | 2010 |
[Immunosuppressive therapy and tuberculosis].
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Antitubercular Agents; Arthritis, Rheumatoid; Enzyme-L | 2010 |
[Evaluation of the GenoType MTBDRplus assay for rifampin and isoniazid susceptibility testing of Mycobacterium tuberculosis].
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Microbial Sensitivit | 2010 |
Tuberculous uveitis.
Topics: Antitubercular Agents; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Humans; Interfe | 2010 |
Validation of the GenoType MTBDRplus assay for detection of MDR-TB in a public health laboratory in Thailand.
Topics: Antitubercular Agents; Bacteriological Techniques; DNA, Bacterial; Drug Resistance, Multiple, Bacter | 2010 |
Role of 2-month sputum smears in predicting culture conversion in pulmonary tuberculosis.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Ethambutol; Female; Humans; Isoniazid; Male; | 2011 |
Validation of the GenoType MTBDRplus assay for diagnosis of multidrug resistant tuberculosis in South Vietnam.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Genotype; Humans; Isoni | 2010 |
Evaluation of seven tests for the rapid detection of multidrug-resistant tuberculosis in Uganda.
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; R | 2010 |
Simultaneous determination of isoniazid, rifampicin, levofloxacin in mouse tissues and plasma by high performance liquid chromatography-tandem mass spectrometry.
Topics: Animals; Antibiotics, Antitubercular; Brain Chemistry; Chromatography, High Pressure Liquid; Female; | 2010 |
High-resolution melting curve analysis for rapid detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis clinical isolates.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; Codon; DNA Primers; DNA-Directed RNA Polymerase | 2010 |
Rifampin-isoniazid oligonucleotide typing: an alternative format for rapid detection of multidrug-resistant Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Bacteriological Techniques; Catalase; DNA-Directed RNA Po | 2010 |
[Performances of the assay MTBDRplus(®) in the surveillance of rifampicin resistance in Mycobacterium tuberculosis].
Topics: Antitubercular Agents; Bacterial Proteins; Codon; Data Collection; Djibouti; DNA-Directed RNA Polyme | 2011 |
Simultaneous determination of isoniazid, pyrazinamide, rifampicin and acetylisoniazid in human plasma by high-performance liquid chromatography.
Topics: Calibration; Chromatography, High Pressure Liquid; Humans; Isoniazid; Pyrazinamide; Rifampin; Sensit | 2010 |
Utility of Microscopic Observation of Drug Susceptibility (MODS) assay for Mycobacterium tuberculosis in resource constrained settings.
Topics: Antitubercular Agents; Developing Countries; Humans; India; Isoniazid; Microbial Sensitivity Tests; | 2010 |
Reliability of the MODS assay decentralisation process in three health regions in Peru.
Topics: Accreditation; Antitubercular Agents; Clinical Laboratory Techniques; Humans; Isoniazid; Microbial S | 2011 |
Use of cloud point extraction with derivatizing reagent for the extraction and determination of isoniazid.
Topics: Benzaldehydes; Calibration; Chemical Fractionation; Chromatography, High Pressure Liquid; Humans; Hy | 2011 |
Evaluation of the performance of nitrate reductase assay for rapid drug-susceptibility testing of mycobacterium tuberculosis in north India.
Topics: Antitubercular Agents; Ethambutol; Humans; India; Isoniazid; Microbial Sensitivity Tests; Mycobacter | 2011 |
Multiplex allele-specific polymerase chain reaction for detection of isoniazid resistance in Mycobacterium tuberculosis.
Topics: Alleles; Antitubercular Agents; Bacterial Proteins; Catalase; DNA Primers; Drug Resistance, Bacteria | 2011 |
A rapid detection of multidrug-resistant Mycobacterium tuberculosis by a nitrate reductase assay on blood agar.
Topics: Agar; Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Microbial Sens | 2011 |
Pyrosequencing for rapid molecular detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis strains and clinical specimens.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Humans; Isoniazid; Microbial Sensitivity Tests; M | 2011 |
DNA extracted from stained sputum smears can be used in the MTBDRplus assay.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Isoniazid; Microbial Sens | 2011 |
Rapid detection of isoniazid, rifampin, and ofloxacin resistance in Mycobacterium tuberculosis clinical isolates using high-resolution melting analysis.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Isoniaz | 2011 |
Drug resistance in Mycobacterium tuberculosis clinical isolates from Brazil: phenotypic and genotypic methods.
Topics: Antitubercular Agents; Brazil; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Genes, MDR; H | 2011 |
Field assessment of the direct nitrate reductase assay for rapid detection of multidrug-resistant tuberculosis in Honduras.
Topics: Antitubercular Agents; Honduras; Humans; Isoniazid; Microbial Sensitivity Tests; Nitrate Reductase; | 2011 |
Utility of nitrate reductase assay for detection of multidrug-resistant Mycobacterium tuberculosis in a low resource setting.
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; N | 2011 |
Integrated detection of multi- and extensively drug-resistant tuberculosis using the nitrate reductase assay.
Topics: Antitubercular Agents; Colorimetry; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; E | 2012 |
Genotype MTBDRplus for direct detection of Mycobacterium tuberculosis and drug resistance in strains from gold miners in South Africa.
Topics: Adult; Antitubercular Agents; Bacterial Proteins; Cross-Sectional Studies; DNA-Directed RNA Polymera | 2012 |
First evaluation of an improved assay for molecular genetic detection of tuberculosis as well as rifampin and isoniazid resistances.
Topics: Antitubercular Agents; Bacterial Proteins; DNA-Directed RNA Polymerases; DNA, Bacterial; Humans; Iso | 2012 |
Evaluation of the GenoType® MTBDRplus assay and identification of a rare mutation for improving MDR-TB detection.
Topics: Antitubercular Agents; China; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Genotype; Humans | 2012 |
Analysis of gene mutations associated with isoniazid, rifampicin and ethambutol resistance among Mycobacterium tuberculosis isolates from Ethiopia.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Bacterial Proteins; Catalase; Child; DNA-Directed RN | 2012 |
Assessing the utility of three TaqMan probes for the diagnosis of tuberculosis and resistance to rifampin and isoniazid in Veracruz, México.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polymerases; Genetic Variation | 2012 |
Rapid direct testing of susceptibility of Mycobacterium tuberculosis to isoniazid and rifampin on nutrient and blood agar in resource-starved settings.
Topics: Agar; Antitubercular Agents; Culture Media; Developing Countries; Humans; Isoniazid; Microbial Sensi | 2012 |
A simple and economical in-house phage technique for the rapid detection of rifampin, isoniazid, ethambutol, streptomycin, and ciprofloxacin drug resistance in Mycobacterium tuberculosis, directly on decontaminated sputum samples.
Topics: Adolescent; Adult; Aged; Antibiotics, Antitubercular; Ciprofloxacin; Ethambutol; Female; Humans; Iso | 2012 |
Evaluation of microscopic observation drug susceptibility assay for diagnosis of multidrug-resistant tuberculosis in Viet Nam.
Topics: Adult; Antitubercular Agents; Culture Media; Drug Resistance, Multiple, Bacterial; Early Diagnosis; | 2012 |
Training laboratory technicians from the Ethiopian periphery in the MODS technique enables rapid and low-cost diagnosis of Mycobacterium tuberculosis infection.
Topics: Antitubercular Agents; Bacteriological Techniques; Ethiopia; Humans; Isoniazid; Israel; Laboratory P | 2012 |
The GenoType® MTBDRplus assay for detection of drug resistance in Mycobacterium tuberculosis in Sweden.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polymerases; DNA, Bacterial; D | 2012 |
The cost-effectiveness of tuberculosis preventive therapy for HIV-infected individuals in southern India: a trial-based analysis.
Topics: Adult; Clinical Trials as Topic; Cohort Studies; Cost-Benefit Analysis; Ethambutol; Female; HIV Infe | 2012 |
Should tuberculin skin testing be a prerequisite to prolonged IPT for HIV-infected adults?
Topics: Adult; Antitubercular Agents; HIV Infections; Humans; Infection Control; Isoniazid; Mass Screening; | 2012 |
Microscopic observation drug susceptibility assay in the diagnosis of multidrug-resistant tuberculosis.
Topics: Adult; Aged; Antitubercular Agents; Egypt; Female; Humans; Isoniazid; Male; Microbial Sensitivity Te | 2012 |
Rapid detection of rifampicin, isoniazid and streptomycin resistance in Mycobacterium tuberculosis clinical isolates by high-resolution melting curve analysis.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Micr | 2012 |
The Colour Test for drug susceptibility testing of Mycobacterium tuberculosis strains.
Topics: Antitubercular Agents; Ciprofloxacin; Color; Drug Resistance, Multiple, Bacterial; Estonia; Extensiv | 2012 |
In-house, simple & economical phage technique for rapid detection of rifampicin, isoniazid, ethambutol, streptomycin & ciprofloxacin drug resistance using Mycobacterium tuberculosis isolates.
Topics: Antitubercular Agents; Bacteriophages; Ciprofloxacin; Ethambutol; Humans; Isoniazid; Microbial Sensi | 2012 |
Use of multiplex allele-specific polymerase chain reaction (MAS-PCR) to detect multidrug-resistant tuberculosis in Panama.
Topics: Alleles; Antitubercular Agents; Bacterial Proteins; Catalase; Drug Resistance, Multiple, Bacterial; | 2012 |
Study of rifampicin and isoniazid resistance mutation genes of M. tuberculosis isolates in Nepal.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polymerases; DNA, Bacterial; D | 2011 |
Characterization of Mycobacterium tuberculosis isolated from cancer patients with suspected tuberculosis infection in Egypt: identification, prevalence, risk factors and resistance pattern.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Bacteriological Techniques; Child; Drug Resistance, | 2012 |
Comparative evaluation of the microplate nitrate reductase assay and the rezasurin microtitre assay for the rapid detection of multidrug resistant Mycobacterium tuberculosis clinical isolates.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Microbial Sensitivit | 2012 |
Point-of-care urine tests for smoking status and isoniazid treatment monitoring in adult patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Cotinine; Female; Humans; Isoniaz | 2012 |
Indirect supportive evidence for diagnosis of tuberculosis-related uveitis: from the tuberculin skin test to the new interferon gamma release assays.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Drug Therapy, Combination; | 2013 |
Does an interferon-gamma release assay change practice in possible latent tuberculosis?
Topics: Adult; Antitubercular Agents; Disease Progression; Drug Therapy, Combination; Female; Humans; Interf | 2013 |
Evaluation of biochip system in determining isoniazid and rifampicin resistances of mycobacterium tuberculosis in sputum samples.
Topics: Antitubercular Agents; China; Drug Resistance, Multiple, Bacterial; High-Throughput Screening Assays | 2012 |
Rapid genotypic detection of rpoB and katG gene mutations in Mycobacterium tuberculosis clinical isolates from Northern India as determined by MAS-PCR.
Topics: Adult; Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polymerases; DNA, Bacte | 2013 |
Comparison of line probe assay with liquid culture for rapid detection of multi-drug resistance in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; DNA-Directed RNA Polymerases; Drug Resistance, Multiple; | 2012 |
Validation of a RP-LC method for the simultaneous determination of isoniazid, pyrazinamide and rifampicin in a pharmaceutical formulation.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Drug Combinations; Isoniazid; Pharmaceu | 2002 |
Advantages of glutamate dehydrogenase as a blood biomarker of acute hepatic injury in rats.
Topics: Acute Disease; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Biomarkers; Chemical and | 2002 |
Quality assurance programme for drug susceptibility testing of Mycobacterium tuberculosis in the WHO/IUATLD Supranational Reference Laboratory Network: five rounds of proficiency testing, 1994-1998.
Topics: Antitubercular Agents; Ethambutol; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosi | 2002 |
[Bioavailability of isoniazid in healthy volunteers--fast and slow INH acetylators].
Topics: Acetylation; Adult; Antitubercular Agents; Arylamine N-Acetyltransferase; Biological Availability; H | 2002 |
The value of urine testing for verifying adherence to anti-tuberculosis chemotherapy in children and adults in Uganda.
Topics: 1-Butanol; Adult; Antitubercular Agents; Child; False Negative Reactions; False Positive Reactions; | 2002 |
Chemotherapeutic activity against murine tuberculosis of once weekly administered drugs (isoniazid and rifampicin) encapsulated in liposomes.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Dose-Response Relationship, Drug; Drug | 2002 |
Rapid detection of multidrug-resistant Mycobacterium tuberculosis using the mycobacteria growth indicator tube (MGIT) system.
Topics: Antitubercular Agents; Bacteriological Techniques; Culture Media; Humans; Isoniazid; Microbial Sensi | 2002 |
Bactericidal and sterilizing activities of antituberculosis drugs during the first 14 days.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Confidence Intervals; D | 2003 |
Bactericidal and sterilizing activities of antituberculosis drugs during the first 14 days.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Confidence Intervals; D | 2003 |
Bactericidal and sterilizing activities of antituberculosis drugs during the first 14 days.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Confidence Intervals; D | 2003 |
Bactericidal and sterilizing activities of antituberculosis drugs during the first 14 days.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Colony Count, Microbial; Confidence Intervals; D | 2003 |
Rapid and simple MTT method for rifampicin and isoniazid susceptibility testing of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Humans; In Vitro Techniques; Isoniazid; Microbial | 2002 |
Use of receiver operating characteristic curves to assess the performance of a microdilution assay for determination of drug susceptibility of clinical isolates of Mycobacterium tuberculosis.
Topics: Agar; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Microbial; Ethambutol; Hu | 2003 |
Urine color test to monitor isoniazid compliance: "pissin' in the wind"?
Topics: Antitubercular Agents; Directly Observed Therapy; Humans; Isoniazid; Patient Compliance; Reagent Str | 2003 |
Use of the urine color test to monitor compliance with isoniazid treatment of latent tuberculosis infection.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Child, Preschool; Female; Humans; Infant; Iso | 2003 |
Improved real-time PCR for rapid detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis clinical isolates.
Topics: Base Sequence; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Female; Humans; Isoniazid; Male | 2003 |
A novel thiocationic liposomal formulation of antisense oligonucleotides with activity against Mycobacterium tuberculosis.
Topics: Analysis of Variance; Animals; Antitubercular Agents; Base Sequence; Chemistry, Pharmaceutical; Drug | 2003 |
Follow-up of compliance with tuberculosis treatment in children: monitoring by urine tests.
Topics: Antitubercular Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administratio | 2003 |
SPECIFICITY OF THE ISONIAZID DROP TEST FOR CONTROL OF DOMICILIARY TREATMENT OF TUBERCULOSIS.
Topics: Antitubercular Agents; Body Fluids; Chemistry Techniques, Analytical; Chloramines; Cyanides; Double- | 1964 |
Detection of a point mutation associated with high-level isoniazid resistance in Mycobacterium tuberculosis by using real-time PCR technology with 3'-minor groove binder-DNA probes.
Topics: 3' Untranslated Regions; Antitubercular Agents; DNA Probes; Drug Resistance, Bacterial; Humans; Ison | 2003 |
Detection of resistance to isoniazid by denaturing gradient-gel electrophoresis DNA sequencing in Mycobacterium tuberculosis clinical isolates.
Topics: Antitubercular Agents; Bacterial Proteins; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, | 2003 |
Detection of isoniazid and rifampin resistance in Mycobacterium tuberculosis strains by single-strand conformation polymorphism analysis and restriction fragment length polymorphism.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Humans; Isoniazid; Mycobacterium tuberculosis; Po | 2003 |
Molecular analysis of isoniazid resistance in Mycobacterium tuberculosis isolates recovered from South Korea.
Topics: Bacterial Proteins; Chi-Square Distribution; DNA Mutational Analysis; Drug Resistance, Bacterial; Fe | 2003 |
[Establishment of a method with micro-channel electrophoresis for detecting the mutations of isoniazid-resistant genes in Mycobacterium tuberculosis].
Topics: Antitubercular Agents; Bacterial Proteins; DNA, Bacterial; Drug Resistance, Bacterial; Electrophores | 2003 |
Evaluation of the fully automated Bactec MGIT 960 system for the susceptibility testing of Mycobacterium tuberculosis to first-line drugs: a multicenter study.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Ethambutol; Humans; Isoniazid; Microbia | 2004 |
Sensitive indirect spectrophotometric determination of isoniazid.
Topics: Antitubercular Agents; Copper; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Ions; I | 2004 |
Drug susceptibility testing of Mycobacterium tuberculosis by the broth microdilution method with 7H9 broth.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Ethambutol; Humans; Isoniazid; Microbial Sensitiv | 2004 |
Direct detection of rifampin- and isoniazid-resistant Mycobacterium tuberculosis in auramine-rhodamine-positive sputum specimens by real-time PCR.
Topics: Antitubercular Agents; Benzophenoneidum; DNA, Bacterial; Drug Resistance, Bacterial; Genotype; Human | 2004 |
Standardization of the method for estimation of ethambutol in pharmaceutical preparations and biological fluid.
Topics: Antitubercular Agents; Chemistry, Clinical; Chromatography; Dose-Response Relationship, Drug; Ethamb | 2004 |
[The use of gene chip in detecting Mycobacterium tuberculosis resistant to rifampin and isoniazid].
Topics: Drug Resistance, Bacterial; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tubercul | 2004 |
Drug susceptibility testing of Mycobacterium tuberculosis with nitrate reductase assay.
Topics: Antitubercular Agents; Color; Ethambutol; Ethylenediamines; Free Radical Scavengers; Isoniazid; Micr | 2004 |
Chemiluminescence detection of isoniazid using Ru(phen)3(2+)-isoniazid-Ce(IV) system.
Topics: Calibration; Cerium; Isoniazid; Luminescent Agents; Luminescent Measurements; Organometallic Compoun | 2004 |
Direct injection of solid-phase extraction eluents onto silica columns for the analysis of polar compounds isoniazid and cetirizine in plasma using hydrophilic interaction chromatography with tandem mass spectrometry.
Topics: Animals; Blood Chemical Analysis; Cetirizine; Chromatography, High Pressure Liquid; Dogs; Flow Injec | 2004 |
Rapid, automated, nonradiometric susceptibility testing of Mycobacterium tuberculosis complex to four first-line antituberculous drugs used in standard short-course chemotherapy.
Topics: Antitubercular Agents; Colony Count, Microbial; Culture Media; Drug Resistance, Multiple, Bacterial; | 2004 |
Comparative evaluation of the nitrate reduction assay, the MTT test, and the resazurin microtitre assay for drug susceptibility testing of clinical isolates of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Ethambutol; Formazans; Isoniazid; Micro | 2005 |
Use of fluorescence resonance energy transfer for rapid detection of isoniazid resistance in Mycobacterium tuberculosis clinical isolates.
Topics: Drug Resistance, Bacterial; Fluorescence Resonance Energy Transfer; Isoniazid; Microbial Sensitivity | 2005 |
Development of a pyrosequencing approach for rapid screening of rifampin, isoniazid and ethambutol-resistant Mycobacterium tuberculosis.
Topics: Antibiotics, Antitubercular; Codon; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Microb | 2005 |
Susceptibilities of Mycobacterium tuberculosis to isoniazid and rifampin on blood agar.
Topics: Agar; Antitubercular Agents; Blood; Culture Media; Humans; Isoniazid; Microbial Sensitivity Tests; M | 2005 |
Direct detection in clinical samples of multiple gene mutations causing resistance of Mycobacterium tuberculosis to isoniazid and rifampicin using fluorogenic probes.
Topics: Antitubercular Agents; Drug Resistance, Bacterial; Fluorescent Dyes; Humans; Isoniazid; Mutation; My | 2005 |
Evaluation of hybridisation on oligonucleotide microarrays for analysis of drug-resistant Mycobacterium tuberculosis.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Myco | 2005 |
Validation of a rapid method for detection of M. tuberculosis resistance to isoniazid and rifampin in Lima, Peru.
Topics: Colorimetry; Drug Resistance, Microbial; Humans; Isoniazid; Mycobacterium tuberculosis; Peru; Prospe | 2005 |
A liquid chromatography/tandem mass spectrometry method for the simultaneous quantification of isoniazid and ethambutol in human plasma.
Topics: Administration, Oral; Calibration; Chromatography, Liquid; Ethambutol; Humans; Isoniazid; Male; Sens | 2005 |
Simultaneous determination of rifampicin and isoniazid by continuous-flow chemiluminescence with artificial neural network calibration.
Topics: Algorithms; Antitubercular Agents; Calibration; Complex Mixtures; Drug Combinations; Flow Injection | 2005 |
Simple means to alleviate sensitivity loss by trifluoroacetic acid (TFA) mobile phases in the hydrophilic interaction chromatography-electrospray tandem mass spectrometric (HILIC-ESI/MS/MS) bioanalysis of basic compounds.
Topics: Acetic Acid; Chromatography, Liquid; Cotinine; Ethionamide; Fluconazole; Humans; Isoniazid; Nicotine | 2005 |
Simultaneous detection of isoniazid, rifampin, and ethambutol resistance of Mycobacterium tuberculosis by a single multiplex allele-specific polymerase chain reaction (PCR) assay.
Topics: Alleles; Antitubercular Agents; Culture Media; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; | 2005 |
Comparison of redox and D29 phage methods for detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Costs and Cost Analysis; Drug Resistance, Bacterial; Isoniazid; Microbial Sen | 2006 |
Evaluation of the CombiChip Mycobacteria Drug-Resistance detection DNA chip for identifying mutations associated with resistance to isoniazid and rifampin in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Codon; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Bacterial; G | 2006 |
Screening for tuberculosis prior to isoniazid preventive therapy among HIV-infected gold miners in South Africa.
Topics: Adult; Antitubercular Agents; Cross-Sectional Studies; Gold; HIV Infections; Humans; Isoniazid; Male | 2006 |
Rapid susceptibility test for Mycobacterium tuberculosis to isoniazid and rifampin with resazurin method in screw-cap tubes.
Topics: Antitubercular Agents; Drug Resistance, Microbial; False Positive Reactions; Humans; Indicators and | 2006 |
Evaluation of a novel kit for use with the BacT/ALERT 3D system for drug susceptibility testing of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacteriological Techniques; Culture Media; Drug Resistance, Bacterial; Ethamb | 2006 |
Cost-effectiveness of including tuberculin skin testing in an IPT program for HIV-infected persons in Uganda.
Topics: Antitubercular Agents; Cost-Benefit Analysis; HIV Infections; Humans; Isoniazid; Program Evaluation; | 2006 |
Evaluation of the Genotype MTBDR assay for rapid detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis isolates.
Topics: Amino Acid Substitution; Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polym | 2006 |
Flow-injection chemiluminescence sensor for determination of isoniazid in urine sample based on molecularly imprinted polymer.
Topics: Flow Injection Analysis; Humans; Isoniazid; Luminescent Measurements; Luminol; Methacrylates; Period | 2007 |
Use of smear-positive samples to assess the PCR-based genotype MTBDR assay for rapid, direct detection of the Mycobacterium tuberculosis complex as well as its resistance to isoniazid and rifampin.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polymerases; Drug Resistance, | 2006 |
Evaluation of rapid alternative methods for drug susceptibility testing in clinical isolates of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tub | 2006 |
Rapid and low-cost colorimetric method using 2,3,5-triphenyltetrazolium chloride for detection of multidrug-resistant Mycobacterium tuberculosis.
Topics: Antibiotics, Antitubercular; Bacteriological Techniques; Drug Resistance, Multiple, Bacterial; Human | 2006 |
[The mycolic acids analysis with HPLC technique in drug susceptibility testing of Mycobacterium tuberculosis strains].
Topics: Antitubercular Agents; Bacteriological Techniques; Biomarkers; Chromatography, High Pressure Liquid; | 2006 |
Rapid antibiotic susceptibility testing of Mycobacterium tuberculosis: its utility in resource poor settings.
Topics: Antitubercular Agents; Colorimetry; Drug Resistance, Bacterial; Humans; Isoniazid; Microbial Sensiti | 2006 |
Evaluation of microscopic observation drug susceptibility assay for detection of multidrug-resistant Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Ethiopia; Fema | 2007 |
Optimization of a stability-indicating HPLC method for the simultaneous determination of rifampicin, isoniazid, and pyrazinamide in a fixed-dose combination using artificial neural networks.
Topics: Biological Availability; Chromatography, High Pressure Liquid; Drug Combinations; Hydrogen-Ion Conce | 2007 |
Evaluation of rifampicin and isoniazid susceptibility testing of Mycobacterium tuberculosis by a mycobacteriophage D29-based assay.
Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Microbial Sensitivit | 2007 |
PCR-restriction fragment length polymorphism for rapid, low-cost identification of isoniazid-resistant Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; Drug Resistance, Bacterial; Humans; Isoniazid; | 2007 |
Validation of a rapid micellar electrokinetic capillary chromatographic method for the simultaneous determination of isoniazid and pyridoxine hydrochloride in pharmaceutical formulation.
Topics: Chromatography, Micellar Electrokinetic Capillary; Isoniazid; Pharmaceutical Preparations; Pyridoxin | 2007 |
Cost-effectiveness of interferon-gamma release assay screening for latent tuberculosis infection treatment in Germany.
Topics: Adult; Antitubercular Agents; Carrier State; Cost-Benefit Analysis; False Positive Reactions; Female | 2007 |
Evaluation of the resazurin assay for the detection of multidrug-resistant Mycobacterium tuberculosis in Madagascar.
Topics: Antitubercular Agents; Colorimetry; Feasibility Studies; Humans; Indicators and Reagents; Isoniazid; | 2007 |
Evaluation of the GenoType MTBDRplus assay for rifampin and isoniazid susceptibility testing of Mycobacterium tuberculosis strains and clinical specimens.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; DNA-Directed RNA Polymerases; DNA, Bacterial; D | 2007 |
[The significance of spoligotyping method in epidemiological investigations of tuberculosis].
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Bacterial Typing Techniques; Cluster Analysis | 2007 |
A new Multi-PCR-SSCP assay for simultaneous detection of isoniazid and rifampin resistance in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Isoniazid; Microbial Sens | 2007 |
[Comparative study of bactec MGIT 960 AST and conventional proportion method using Ogawa medium for the drug susceptibility testing of Mycobacterium tuberculosis to isoniazid].
Topics: Antitubercular Agents; Culture Media; Drug Resistance, Bacterial; Humans; Isoniazid; Japan; Microbia | 2007 |
Searching for a needle in a haystack: use of ICD-9-CM codes in drug-induced liver injury.
Topics: Adolescent; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Chemical and Drug Induced Li | 2007 |
Evaluation of the Arkansas method of urine testing for isoniazid in South Africa.
Topics: Adult; Antitubercular Agents; Cross-Sectional Studies; Humans; Isoniazid; Male; Middle Aged; Patient | 2007 |
Evaluation of Mycobacterium smegmatis as a possible surrogate screen for selecting molecules active against multi-drug resistant Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Biomarkers; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; | 2007 |
Fast evaluation of oxidative DNA damage by liquid chromatography-electrospray tandem mass spectrometry coupled with precision-cut rat liver slices.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Chromatography, Liquid; Deoxyguanosine; DNA Damage; Humans; Is | 2007 |
Rapid molecular screening for multidrug-resistant tuberculosis in a high-volume public health laboratory in South Africa.
Topics: Antitubercular Agents; Genotype; Humans; Isoniazid; Microbial Sensitivity Tests; Molecular Probe Tec | 2008 |
Microscopic-observation drug susceptibility assay provides rapid and reliable identification of MDR-TB.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Drug Resistance, Multiple, Bacterial; Female; Human | 2008 |
Interferon-gamma responses after isoniazid chemotherapy for latent tuberculosis.
Topics: Adult; Aged; Antitubercular Agents; Biomarkers; Dose-Response Relationship, Drug; Female; Humans; In | 2008 |
L5 luciferase reporter mycobacteriophages: a sensitive tool for the detection and assay of live mycobacteria.
Topics: Bacterial Typing Techniques; Base Sequence; Drug Resistance, Microbial; Ethambutol; Genes, Insect; G | 1995 |
Rapid, specific and sensitive method for isoniazid determination in serum.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Humans; Isoniazid; Reproducibility of R | 1996 |
Determination of isonicotinic acid in the presence of isoniazid and acetylisoniazid. Studies on isonicotinic acid formation from isoniazid in isolated rat hepatocytes.
Topics: Animals; Chromatography, High Pressure Liquid; In Vitro Techniques; Isoniazid; Isonicotinic Acids; L | 1996 |
High-performance liquid chromatographic determination of isoniazid, acetylisoniazid and hydrazine in biological fluids.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Drug Stability; Humans; Hydrazines; Hyd | 1995 |
KatG sequence deletion is not the major cause of isoniazid resistance in Japanese and Yemeni Mycobacterium tuberculosis isolates.
Topics: Bacterial Proteins; Base Sequence; DNA, Bacterial; Drug Resistance, Microbial; Drug Resistance, Mult | 1995 |
Simultaneous determination of rifampicin, isoniazid and pyrazinamid by high performance thin layer chromatography.
Topics: Antitubercular Agents; Chromatography, Thin Layer; Drug Combinations; Isoniazid; Pyrazinamide; Repro | 1996 |
Genotypic assessment of isoniazid and rifampin resistance in Mycobacterium tuberculosis: a blind study at reference laboratory level.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Bacteriological Techniques; Base Sequence; DNA P | 1997 |
Use of polymerase chain reaction single-strand conformation polymorphism (PCR-SSCP) analysis to detect a point mutation in the catalase-peroxidase gene (katG) of Mycobacterium tuberculosis.
Topics: Bacterial Proteins; DNA, Bacterial; Drug Resistance, Microbial; Isoniazid; Microbial Sensitivity Tes | 1997 |
Detection of resistance to isoniazid, rifampin, and streptomycin in clinical isolates of Mycobacterium tuberculosis by molecular methods.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Base Sequence; DNA, Bacterial; Drug Resistance, | 1997 |
The cost-effectiveness of preventing tuberculosis in physicians using tuberculin skin testing or a hypothetical vaccine.
Topics: Adult; Aged; Antitubercular Agents; BCG Vaccine; Cause of Death; Chemoprevention; Cooperative Behavi | 1997 |
Quantitative-competitive polymerase chain reaction for rapid susceptibility testing of Mycobacterium tuberculosis to isoniazid.
Topics: Antitubercular Agents; Colony Count, Microbial; DNA, Bacterial; Drug Resistance, Microbial; Evaluati | 1997 |
Therapeutic efficacies of isoniazid and rifampin encapsulated in lung-specific stealth liposomes against Mycobacterium tuberculosis infection induced in mice.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Dose-Response Relationship, Drug; Isoni | 1997 |
Mycobacterial growth indicator tube for susceptibility testing of Mycobacterium tuberculosis to isoniazid and rifampin.
Topics: Antitubercular Agents; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; R | 1997 |
Monitored isoniazid prophylaxis for low-risk tuberculin reactors older than 35 years of age: a risk-benefit and cost-effectiveness analysis.
Topics: Adult; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cost-Benefit Analysis; D | 1997 |
Quality assurance programme for drug susceptibility testing of Mycobacterium tuberculosis in the WHO/IUATLD Supranational Laboratory Network: first round of proficiency testing.
Topics: Antitubercular Agents; Clinical Laboratory Information Systems; Drug Therapy, Combination; Ethambuto | 1997 |
Detection of rifampicin and isoniazid resistances of Mycobacterium tuberculosis strains by particle counting immunoassay (PACIA).
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Humans; Immunoassay; Isoniazid; Latex Fixat | 1997 |
Rapid, low-technology MIC determination with clinical Mycobacterium tuberculosis isolates by using the microplate Alamar Blue assay.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Bacteriological Techniques; Coloring Agents; Cul | 1998 |
Sensitive liquid chromatographic technique to measure isoniazid in alveolar cells, bronchoalveolar lavage and plasma in HIV-infected patients.
Topics: Administration, Oral; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Chromatogr | 1998 |
Should we take a history of prior treatment, and check sputum status at 2-3 months when treating patients for tuberculosis?
Topics: Adult; Ambulatory Care; Antibiotics, Antitubercular; Antitubercular Agents; Cohort Studies; Confiden | 1998 |
Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes.
Topics: Animals; Antibodies; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Biomarkers; Clofibrate; Cyt | 1998 |
A reproducible, simple, and sensitive high-performance capillary electrophoresis method for simultaneous determination of capreomycin, ofloxacin and pasiniazide in urine.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Capreomycin; Electrophoresis, Capillary; Humans; Isoniazi | 1998 |
Stability of isoniazid in isoniazid syrup: formation of hydrazine.
Topics: Antitubercular Agents; Chromatography, Gas; Dosage Forms; Drug Stability; Isoniazid; Sensitivity and | 1998 |
Rapid film-based determination of antibiotic susceptibilities of Mycobacterium tuberculosis strains by using a luciferase reporter phage and the Bronx Box.
Topics: Antitubercular Agents; Bacteriophages; Drug Resistance, Microbial; Evaluation Studies as Topic; Fire | 1999 |
Tuberculosis vaccination versus isoniazid preventive therapy: a decision analysis to determine the preferred strategy of tuberculosis prevention in HIV-infected adults in the developing world.
Topics: Adult; Antitubercular Agents; BCG Vaccine; Decision Support Techniques; Developing Countries; HIV In | 1999 |
Chemotherapy of tuberculosis in mice using single implants of isoniazid and pyrazinamide.
Topics: Administration, Oral; Analysis of Variance; Animals; Antitubercular Agents; Biocompatible Materials; | 1999 |
Stability of rifampicin in dissolution medium in presence of isoniazid.
Topics: Antitubercular Agents; Chromatography, Thin Layer; Drug Compounding; Drug Stability; Hydrochloric Ac | 1999 |
Determination of rifampicin, isoniazid and pyrazinamide by high performance liquid chromatography after their simultaneous extraction from plasma.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Humans; Isoniazid; Pyrazinamide; Rifamp | 1999 |
Direct drug susceptibility test for tubercle bacilli by the sputum swab culture method.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Bacteriological Techniques; Culture Media; Human | 2000 |
Rapid, efficient detection and drug susceptibility testing of Mycobacterium tuberculosis in sputum by microscopic observation of broth cultures. The Tuberculosis Working Group in Peru.
Topics: Antitubercular Agents; Bacterial Typing Techniques; Costs and Cost Analysis; Drug Resistance, Microb | 2000 |
Genomic mutations in the katG, inhA and aphC genes are useful for the prediction of isoniazid resistance in Mycobacterium tuberculosis isolates from Kwazulu Natal, South Africa.
Topics: Alleles; Antitubercular Agents; Bacterial Proteins; DNA Mutational Analysis; Drug Resistance, Microb | 2000 |
Comparison of Mycobacterium tuberculosis susceptibility testing performed with BACTEC 460TB (Becton Dickinson) and MB/BacT (Organon Teknika) systems.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Carbon Dioxide; Ethambutol; Humans; Isoniazid; M | 2000 |
Use of automated solid-phase extraction equipment for the determination of isoniazid in milk.
Topics: Animals; Antitubercular Agents; Chromatography, High Pressure Liquid; Drug Residues; Isoniazid; Milk | 2000 |
A flow injection chemiluminescence system for the determination of isoniazid.
Topics: Antitubercular Agents; Isoniazid; Luminescent Measurements; Pharmaceutical Preparations; Reference S | 2000 |
Comparison of two rapid colorimetric methods for determining resistance of mycobacterium tuberculosis to rifampin, isoniazid, and streptomycin in liquid medium.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Colorimetry; Coloring Agents; Drug Resistance, M | 2001 |
Evaluation of mycobacteria growth indicator tube for direct and indirect drug susceptibility testing of Mycobacterium tuberculosis from respiratory specimens in a Siberian prison hospital.
Topics: Antitubercular Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Hospitals, State; Huma | 2001 |
Method for conducting sensitivity analysis.
Topics: Biometry; Humans; Isoniazid; Models, Statistical; Peripheral Nervous System Diseases; Polymorphism, | 1999 |
Higher activity of morphazinamide over pyrazinamide against intracellular.
Topics: Antitubercular Agents; Humans; Isoniazid; Macrophages; Microbial Sensitivity Tests; Mycobacterium tu | 2001 |
Mycolic acid index susceptibility method for Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Microbial; Humans; Isoniazid; Microbial Sensitivity Tests; M | 2001 |
Characteristics of drug resistance and HIV among tuberculosis patients in Mozambique.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Antibiotics, Antitubercular; Child; Child, Pr | 2001 |
Pattern of mycobacterial resistance to four anti-tuberculosis drugs in pulmonary tuberculosis patients in the state of Qatar after the implementation of DOTS and a limited expatriate screening programme.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Child, Preschool; Clinical Protocols; Drug Combinat | 2001 |
Management of tuberculosis.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Humans; Isoniazid; Patient Compliance; Rifampin; | 2001 |
Liquid chromatographic determination of isoniazid, pyrazinamide and rifampicin from pharmaceutical preparations and blood.
Topics: Antitubercular Agents; Chromatography, High Pressure Liquid; Humans; Isoniazid; Pharmaceutical Prepa | 2002 |
Urine testing to monitor adherence to TB preventive therapy.
Topics: Adolescent; Antitubercular Agents; Female; Hispanic or Latino; Humans; Isoniazid; Male; Patient Comp | 2002 |
Rifampin and isoniazid resistance associated mutations in Mycobacterium tuberculosis clinical isolates in Seville, Spain.
Topics: DNA, Bacterial; Drug Resistance, Multiple; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; | 2002 |
Diagnostic criteria for Tuberculous Meningitis.
Topics: Antitubercular Agents; Child; Child, Preschool; Humans; Isoniazid; Mycobacterium tuberculosis; Progn | 2002 |
Rapid indication of multidrug-resistant tuberculosis from liquid cultures using FASTPlaqueTB-RIF, a manual phage-based test.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Automation; Bacteriophages; Cell Culture Techniq | 2002 |
Clinical application of the polymerase chain reaction for a rapid diagnosis of Mycobacterium tuberculosis infection.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Base Sequence; DNA, Bacterial; Drug Therap | 1992 |
Fluorometric determination of isoniazid and its metabolites in urine by high-performance liquid chromatography using in-line derivatization.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Fluorometry; Humans; Hydrogen-Io | 1991 |
Overview of results from the WaterTox intercalibration and environmental testing phase II program: part 2, ecotoxicological evaluation of drinking water supplies.
Topics: Animals; Calibration; Chlorophyta; Daphnia; Hydra; International Cooperation; Laboratories; Lactuca; | 2002 |
Quality of water types in Ukraine evaluated by WaterTox bioassays.
Topics: Animals; Chlorophyta; Daphnia; Environmental Monitoring; Humans; Hydra; Lactuca; Public Health; Sens | 2002 |
Biochemical and functional identification of GABA receptors in Hydra vulgaris.
Topics: Animals; Baclofen; Bicuculline; Binding, Competitive; Diazepam; Feeding Behavior; gamma-Aminobutyric | 1995 |
Quantitative analysis of epithelial cell aggregation in the simple metazoan Hydra reveals a switch from homotypic to heterotypic cell interactions.
Topics: Animals; Antibodies, Monoclonal; Calcium; Cell Adhesion; Cell Aggregation; Cell Communication; Cell | 2001 |