indazoles has been researched along with Sensitivity and Specificity in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (20.83) | 18.2507 |
| 2000's | 6 (25.00) | 29.6817 |
| 2010's | 13 (54.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allal, B; Arellano, C; Chatelut, E; Lafont, T; Le Louedec, F; Paludetto, MN; Puisset, F | 1 |
| Arnold, ME; Buzescu, A; Jemal, M; Ouyang, Z; Pasas-Farmer, S; Peng, Q; Van Vleet, T; Zeng, J; Zheng, N | 1 |
| Bejot, R; Bhakoo, KK; Goggi, JL; Moonshi, SS | 1 |
| Huestis, MA; Jarvis, MJ; Scheidweiler, KB | 1 |
| Götze, L; Hegele, A; Hofmann, R; Keil, C; Nockher, WA; Olbert, P | 1 |
| Bartha, R; Li, AX; McVicar, N; Meakin, SO | 1 |
| Cromarty, AD; Joubert, AM; van Tonder, A | 1 |
| Ali, SM; Balasubramanian, S; Do, IG; Hong, JY; Hornby, Z; Huh, JW; Jang, J; Kang, WK; Kim, HC; Kim, KM; Kim, SH; Kim, ST; Kim, SY; Lee, J; Lee, WY; Li, GG; Lim, HY; Miller, VA; Ou, SH; Park, JO; Park, YA; Park, YS; Ross, JS; Stephens, PJ; Wang, K; Yun, SH | 1 |
| Granovetter, M | 1 |
| Abdulfatah, E; Kukreja, G; Nagasaka, M; Sukari, A; Vaishampayan, U | 1 |
| El-Shourbagy, TA; Norem, K; Wu, H; Zhang, J | 1 |
| Amler, LC; Belvin, M; Berry, L; Friedman, LS; Guan, J; GuhaThakurta, D; Lackner, MR; O'Brien, C; Prior, WW; Punnoose, EA; Sampath, D; Savage, H; Wallin, JJ | 1 |
| Khurana, V; Minocha, M; Mitra, AK | 1 |
| Ahmed, TT; Beijnen, JH; Muilwijk, EW; Schellens, JH; Sparidans, RW; Welzen, ME | 1 |
| Bouska, JJ; de Jong, R; Giranda, VL; Gramling-Evans, EE; Guan, R; Han, EK; Johnson, EF; Klinghofer, V; Leverson, JD; Li, Q; Li, T; Liu, X; Luo, Y; Mamo, M; McGonigal, TP; Mika, AK; Mitten, MJ; Nguyen, PT; Oleksijew, A; Oltersdorf, T; Powlas, JA; Rosenberg, SH; Shi, Y; Shoemaker, AR; Smith, RA; Stoll, VS; Thomas, SA; Woods, KW; Zinker, BA | 1 |
| Huerta, F; Kallin, E; Malmström, J; Ohberg, L; Swahn, BM; Viklund, J; Weigelt, T; Womack, P; Xue, Y | 1 |
| Egger, A; Galanski, MS; Hartinger, CG; Jakupec, MA; Keppler, BK; Reisner, E; Schluga, P | 1 |
| El-Shourbagy, TA; Ji, QC; Kim, JC; Rodila, RC | 1 |
| Agrawal, K; Gupta, AK; Jain, A; Kaskhedikar, SG; Revathi, S; Saraswat, V; Soni, LK | 1 |
| Babbedge, RC; Gaffen, ZA; Hart, SL; Moore, PK; Wallace, P | 1 |
| Brown, NJ; Horton, A; Read, NW; Rumsey, RD | 1 |
| Carlucci, G; Mazzeo, P | 1 |
| Bland-Ward, PA; Moore, PK | 1 |
| Fukano, A; Sudo, K; Tachibana, S; Tanaka, M | 1 |
2 trial(s) available for indazoles and Sensitivity and Specificity
| Article | Year |
|---|---|
[Metastasized renal cell carcinoma. Measurement of plasma levels of the tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib].
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Drug Monitoring; Feasibility Studies; Female; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Sorafenib; Sulfonamides; Sunitinib | 2015 |
Benefits of pazopanib over sunitinib for renal cell carcinoma.
Topics: Angiogenesis Inhibitors; Carcinoma, Renal Cell; Humans; Indazoles; Indoles; Kidney Neoplasms; Patient Safety; Prognosis; Pyrimidines; Pyrroles; Quality of Life; Sensitivity and Specificity; Sulfonamides; Sunitinib; Survival Analysis; Treatment Outcome | 2016 |
22 other study(ies) available for indazoles and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous monitoring of pazopanib and its metabolites by UPLC-MS/MS.
Topics: Aged; Calibration; Chromatography, High Pressure Liquid; Clinical Trials, Phase I as Topic; Humans; Indazoles; Limit of Detection; Microsomes, Liver; Multicenter Studies as Topic; Pyrimidines; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Sulfonamides; Tandem Mass Spectrometry | 2018 |
A simplified and completely automated workflow for regulated LC-MS/MS bioanalysis using cap-piercing direct sampling and evaporation-free solid phase extraction.
Topics: Animals; Calcitonin Gene-Related Peptide Receptor Antagonists; Chromatography, Liquid; Dogs; Equipment Design; Haplorhini; High-Throughput Screening Assays; Humans; Indazoles; Pyrazoles; Quinazolinones; Receptors, Corticotropin-Releasing Hormone; Sensitivity and Specificity; Solid Phase Extraction; Specimen Handling; Tandem Mass Spectrometry; Triazines | 2013 |
Stratification of 18F-labeled PET imaging agents for the assessment of antiangiogenic therapy responses in tumors.
Topics: Angiogenesis Inhibitors; Animals; Axitinib; Cell Line, Tumor; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Imidazoles; Indazoles; Isotope Labeling; Mice; Neoplasms, Experimental; Peptides, Cyclic; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome | 2013 |
Nontargeted SWATH acquisition for identifying 47 synthetic cannabinoid metabolites in human urine by liquid chromatography-high-resolution tandem mass spectrometry.
Topics: Anisoles; Calibration; Cannabinoids; Chromatography, Liquid; Humans; Hydrolysis; Indazoles; Indoles; Limit of Detection; Naphthalenes; Sensitivity and Specificity; Signal Processing, Computer-Assisted; Substance Abuse Detection; Tandem Mass Spectrometry | 2015 |
Imaging chemical exchange saturation transfer (CEST) effects following tumor-selective acidification using lonidamine.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Contrast Media; Humans; Hydrogen-Ion Concentration; Image Interpretation, Computer-Assisted; Indazoles; Magnetic Resonance Imaging; Mice; Mice, Nude; Molecular Imaging; Reproducibility of Results; Sensitivity and Specificity; Tumor Cells, Cultured | 2015 |
Limitations of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay when compared to three commonly used cell enumeration assays.
Topics: Artifacts; Biological Assay; Cell Count; Cell Line, Tumor; Cell Survival; Deoxyglucose; Glycolysis; Humans; Indazoles; Neutral Red; Observer Variation; Oxazines; Oxidation-Reduction; Pyruvates; Reproducibility of Results; Rhodamines; Sensitivity and Specificity; Staining and Labeling; Tetrazolium Salts; Thiazoles; Xanthenes | 2015 |
Detection of novel and potentially actionable anaplastic lymphoma kinase (ALK) rearrangement in colorectal adenocarcinoma by immunohistochemistry screening.
Topics: Adult; Aged; Aged, 80 and over; Anaplastic Lymphoma Kinase; Antibodies, Monoclonal; Benzamides; Cell Line, Tumor; Colorectal Neoplasms; Crizotinib; Female; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Rearrangement; Genomics; High-Throughput Nucleotide Sequencing; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Indazoles; Male; Middle Aged; Mutation; Phosphorylation; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases; Reproducibility of Results; Republic of Korea; Sensitivity and Specificity; Tissue Array Analysis; Young Adult | 2015 |
Role of Molecular Profiling in Diagnosis of Papillary Renal-cell Cancer Presenting as Cancer of Unknown Primary Site.
Topics: Adult; Aged; Carcinoma, Renal Cell; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Indazoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Neoplasms, Unknown Primary; Pyrimidines; Sensitivity and Specificity; Sulfonamides; Treatment Outcome | 2017 |
Simultaneous determination of a hydrophobic drug candidate and its metabolite in human plasma with salting-out assisted liquid/liquid extraction using a mass spectrometry friendly salt.
Topics: Acetates; Acetonitriles; Calibration; Chromatography, Liquid; Drugs, Investigational; Humans; Hydrophobic and Hydrophilic Interactions; Indazoles; Mass Spectrometry; Phenylurea Compounds; Quality Control; Reference Standards; Sensitivity and Specificity | 2008 |
Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Female; Gene Expression Profiling; Humans; Indazoles; Mammary Neoplasms, Experimental; Mice; Mutation; Neoplasm Transplantation; Oligonucleotide Array Sequence Analysis; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Predictive Value of Tests; Receptor, ErbB-2; Sensitivity and Specificity; Sulfonamides; Xenograft Model Antitumor Assays | 2010 |
Determination of pazopanib (GW-786034) in mouse plasma and brain tissue by liquid chromatography-tandem mass spectrometry (LC/MS-MS).
Topics: Animals; Brain Chemistry; Chromatography, Liquid; Drug Stability; Indazoles; Least-Squares Analysis; Mice; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Sulfonamides; Tandem Mass Spectrometry | 2012 |
Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the tyrosine kinase inhibitor pazopanib in human plasma.
Topics: Aged; Chromatography, Liquid; Drug Monitoring; Drug Stability; Female; Humans; Indazoles; Least-Squares Analysis; Limit of Detection; Male; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Sulfonamides; Tandem Mass Spectrometry | 2012 |
Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Progression; Humans; Indazoles; Indoles; Mice; Mice, SCID; Models, Molecular; Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Sensitivity and Specificity; Substrate Specificity | 2005 |
Design and synthesis of 6-anilinoindazoles as selective inhibitors of c-Jun N-terminal kinase-3.
Topics: Binding Sites; Crystallography, X-Ray; Drug Design; Indazoles; Inhibitory Concentration 50; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinase 14; Mitogen-Activated Protein Kinase 8; Protein Kinase Inhibitors; Protein Structure, Tertiary; Sensitivity and Specificity; Structure-Activity Relationship; Substrate Specificity | 2005 |
Redox behavior of tumor-inhibiting ruthenium(III) complexes and effects of physiological reductants on their binding to GMP.
Topics: Antineoplastic Agents; Ascorbic Acid; Binding Sites; Electrophoresis, Capillary; Glutathione; Guanine Nucleotides; Hydrogen-Ion Concentration; Indazoles; Magnetic Resonance Spectroscopy; Molecular Structure; Organometallic Compounds; Oxidation-Reduction; Ruthenium Compounds; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Time Factors | 2006 |
A high-throughput, fully automated liquid/liquid extraction liquid chromatography/mass spectrometry method for the quantitation of a new investigational drug ABT-869 and its metabolite A-849529 in human plasma samples.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Humans; Indazoles; Microfluidics; Phenylurea Compounds; Reproducibility of Results; Robotics; Sensitivity and Specificity; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization | 2006 |
QSAR analysis of indazole estrogens as selective beta-estrogen receptor ligands: rationalization of physicochemical properties.
Topics: Chemical Phenomena; Chemistry, Physical; Estrogen Receptor beta; Estrogens; Indazoles; Ligands; Molecular Structure; Quantitative Structure-Activity Relationship; Sensitivity and Specificity | 2007 |
7-Nitro indazole, an inhibitor of nitric oxide synthase, exhibits anti-nociceptive activity in the mouse without increasing blood pressure.
Topics: Amino Acid Oxidoreductases; Analgesics; Animals; Blood Pressure; Cerebellum; Formaldehyde; In Vitro Techniques; Indazoles; Male; Mice; Mice, Inbred Strains; Nitric Oxide Synthase; Sensitivity and Specificity | 1993 |
Granisetron and ondansetron: effects on the ileal brake mechanism in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Gastrointestinal Transit; Granisetron; Ileum; Indazoles; Lipids; Male; Ondansetron; Rats; Sensitivity and Specificity; Serotonin Antagonists | 1993 |
High-performance liquid chromatographic determination of 1-benzyl-1H-indazol-3-ol in benzydamine in pharmaceutical formulations.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzydamine; Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Indazoles; Sensitivity and Specificity | 1996 |
7-nitroindazole: an inhibitor of nitric oxide synthase.
Topics: Analgesics; Animals; Aorta; Arginine; Carbachol; Cattle; Cerebellum; Endothelium, Vascular; Enzyme Inhibitors; Female; Indazoles; Isoenzymes; Lung; Male; Mice; Molecular Structure; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitro Compounds; Rabbits; Radioisotope Dilution Technique; Rats; Sensitivity and Specificity; Structure-Activity Relationship; Tritium | 1996 |
Determination of a novel calmodulin antagonist, 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1- (4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate, DY-9760e, in human plasma using solid-phase extraction and high-performan
Topics: Buffers; Calmodulin; Chromatography, High Pressure Liquid; Drug Stability; Humans; Hydrogen-Ion Concentration; Indazoles; Quality Control; Sensitivity and Specificity; Solutions; Spectrometry, Fluorescence | 1999 |