An indoleamine 2,3-dioxygenase 1 that is encoded in the genome of mouse. [OMA:P28776, PRO:DNx]
IDO-1;
EC 1.13.11.52;
Indoleamine-pyrrole 2,3-dioxygenase
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| celecoxib | Mus musculus (house mouse) | IC50 | 0.0060 | 1 | 2 |
| clotrimazole | Mus musculus (house mouse) | IC50 | 51.6000 | 1 | 1 |
| econazole | Mus musculus (house mouse) | IC50 | 11.2000 | 1 | 1 |
| indomethacin | Mus musculus (house mouse) | IC50 | 0.0820 | 1 | 2 |
| lansoprazole | Mus musculus (house mouse) | IC50 | 94.0000 | 1 | 1 |
| miconazole | Mus musculus (house mouse) | IC50 | 17.8000 | 1 | 1 |
| nifedipine | Mus musculus (house mouse) | IC50 | 46.0000 | 1 | 1 |
| pantoprazole | Mus musculus (house mouse) | IC50 | 109.0000 | 1 | 1 |
| sulconazole | Mus musculus (house mouse) | IC50 | 29.3000 | 1 | 1 |
| troglitazone | Mus musculus (house mouse) | IC50 | 61.0000 | 1 | 1 |
| phenylhydrazine | Mus musculus (house mouse) | IC50 | 0.2000 | 1 | 1 |
| 1,4-naphthohydroquinone | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| 2-hydrazinobenzothiazole | Mus musculus (house mouse) | IC50 | 50.5000 | 1 | 1 |
| 5-amino-8-hydroxyquinoline | Mus musculus (house mouse) | IC50 | 1.0000 | 1 | 1 |
| tretinoin | Mus musculus (house mouse) | IC50 | 301.3000 | 1 | 1 |
| tenatoprazole | Mus musculus (house mouse) | IC50 | 100.0000 | 1 | 1 |
| 1-methyltryptophan | Mus musculus (house mouse) | IC50 | 40.0000 | 1 | 1 |
| 4-phenyl-3H-thiazole-2-thione | Mus musculus (house mouse) | IC50 | 20.0000 | 1 | 1 |
| fenretinide | Mus musculus (house mouse) | IC50 | 59.9000 | 1 | 1 |
| 680c91 | Mus musculus (house mouse) | IC50 | 80.0000 | 1 | 1 |
| sildenafil | Mus musculus (house mouse) | IC50 | 100.0000 | 1 | 1 |