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sarcosine and Sensitivity and Specificity

sarcosine has been researched along with Sensitivity and Specificity in 32 studies

cocobetaine: N-alkyl-betaine; cause of shampoo dermatitis

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"Brucellosis is an important zoonosis, and serological surveillance is essential to its control."5.32Epidemiological and serological survey of brucellosis in Mongolia by ELISA using sarcosine extracts. ( Bayarsaikhan, B; Erdenebaatar, J; Jargalsaikhan, E; Kawamoto, K; Makino, S; Shirahata, T; Watarai, M; Yondondorj, A, 2004)
"Conventional IgG-ELISA methods for diagnosing cat scratch disease (CSD) caused by Bartonella hensela are still poor in sensitivity and specificity, which generally employ bacterial whole-cell proteins or N-lauroyl-sarcosine-insoluble proteins as the antigen."3.78Evaluation of IgG ELISA using N-lauroyl-sarcosine-soluble proteins of Bartonella henselae for highly specific serodiagnosis of cat scratch disease. ( Ichihara, K; Kawano, M; Nojima, J; Tanaka, T; Tsuneoka, H; Tsuruoka, K; Yamamoto, M; Yanagihara, M, 2012)
" The influence of hyperhydration on the serum and urinary pharmacokinetic (PK) profiles of rHuEPO was also investigated."2.90Hyperhydration Effect on Pharmacokinetic Parameters and Detection Sensitivity of Recombinant Human Erythropoietin in Urine and Serum Doping Control Analysis of Males. ( Al-Maadheed, M; Athanasiadou, I; Dokoumetzidis, A; El Saftawy, W; Georgakopoulos, C; Valsami, G; Voss, SC, 2019)
"Prostate cancer is usually a disease of elderly men, however, over 40 years of age the tumor can appear at any times."2.50[New challenges and earlier approved methods in the laboratory diagnosis of prostate cancer]. ( Kovács, GL, 2014)
"Sarcosine is an amino acid derivative, which is considered as a key metabolite in various metabolic processes."1.51A highly sensitive DNA aptamer-based fluorescence assay for sarcosine detection down to picomolar levels. ( Canbay, ZÇ; Dinçkaya, E; Evran, S; Özyurt, C, 2019)
" We herein developed a quick detecting method using recombinase polymerase amplification (RPA) combined with lateral flow (LF) strip to detect DNA of Cryptosporidium oocysts in dairy cattle feces."1.43Recombinase polymerase amplification (RPA) combined with lateral flow (LF) strip for equipment-free detection of Cryptosporidium spp. oocysts in dairy cattle feces. ( Ma, JG; Wang, M; Wu, YD; Xu, MJ; Zhang, LX; Zheng, WB; Zhou, DH; Zhu, XQ, 2016)
"Sarcosine levels were overlapping between the prostate cancer cases (median 15."1.42A case control study of sarcosine as an early prostate cancer detection biomarker. ( Ankerst, DP; Hoefler, J; Leach, RJ; Liss, M; Thompson, IM; Zapata, D, 2015)
"Sarcosine, a potential biomarker of prostate cancer, has drawn great attention in recent years."1.40Sensitive determination of the potential biomarker sarcosine for prostate cancer by LC-MS with N,N'-dicyclohexylcarbodiimide derivatization. ( Chen, J; Chen, Z; Zhang, J; Zhang, W, 2014)
"Sarcosine values were not associated with tumor stage (pT2 vs pT3), tumor grade (Gleason score less than 7 vs 7 or greater) or biochemical recurrence."1.37Sarcosine in prostate cancer tissue is not a differential metabolite for prostate cancer aggressiveness and biochemical progression. ( Bethan, B; Jentzmik, F; Jung, K; Kamlage, B; Kristiansen, G; Lein, M; Miller, K; Stephan, C, 2011)
"Sarcosine is an amino acid derivative of N-methylglycine and is involved in the amino acid metabolism and methylation processes that are enriched during prostate cancer progression."1.37Sarcosine as a marker in prostate cancer progression: a rapid and simple method for its quantification in human urine by solid-phase microextraction-gas chromatography-triple quadrupole mass spectrometry. ( Cavaliere, B; Macchione, B; Monteleone, M; Naccarato, A; Sindona, G; Tagarelli, A, 2011)
"Brucellosis is an important zoonosis, and serological surveillance is essential to its control."1.32Epidemiological and serological survey of brucellosis in Mongolia by ELISA using sarcosine extracts. ( Bayarsaikhan, B; Erdenebaatar, J; Jargalsaikhan, E; Kawamoto, K; Makino, S; Shirahata, T; Watarai, M; Yondondorj, A, 2004)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (6.25)18.2507
2000's8 (25.00)29.6817
2010's22 (68.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pacik, D1
Plevova, M1
Urbanova, L1
Lackova, Z1
Strmiska, V1
Necas, A1
Heger, Z2
Adam, V2
Reichel, C1
Gmeiner, G1
Reihlen, P1
Thevis, M1
Schänzer, W1
Athanasiadou, I1
Dokoumetzidis, A1
Voss, SC1
El Saftawy, W1
Al-Maadheed, M1
Valsami, G1
Georgakopoulos, C1
Özyurt, C1
Canbay, ZÇ1
Dinçkaya, E1
Evran, S1
Chen, J1
Zhang, J2
Zhang, W1
Chen, Z2
Wang, G1
Zhou, Y1
Huang, FJ1
Tang, HD1
Xu, XH1
Liu, JJ1
Wang, Y1
Deng, YL1
Ren, RJ1
Xu, W1
Ma, JF1
Zhang, YN1
Zhao, AH1
Chen, SD1
Jia, W1
Ladep, NG1
Dona, AC1
Lewis, MR1
Crossey, MM1
Lemoine, M1
Okeke, E1
Shimakawa, Y1
Duguru, M1
Njai, HF1
Fye, HK1
Taal, M1
Chetwood, J1
Kasstan, B1
Khan, SA1
Garside, DA1
Wijeyesekera, A1
Thillainayagam, AV1
Banwat, E1
Thursz, MR1
Nicholson, JK1
Njie, R1
Holmes, E1
Taylor-Robinson, SD1
Kovács, GL1
Cernei, N1
Krizkova, S1
Masarik, M1
Kopel, P1
Hodek, P1
Zitka, O1
Kizek, R1
Ankerst, DP1
Liss, M1
Zapata, D1
Hoefler, J1
Thompson, IM1
Leach, RJ1
Wu, YD1
Zhou, DH1
Zhang, LX1
Zheng, WB1
Ma, JG1
Wang, M1
Zhu, XQ1
Xu, MJ1
Kumar, D1
Gupta, A1
Mandhani, A1
Sankhwar, SN1
Mi Park, E1
Lee, E1
Jin Joo, H1
Oh, E1
Lee, J1
Lee, JS1
Hobb, RI1
Fields, JA1
Burns, CM1
Thompson, SA1
Jiang, Y1
Cheng, X1
Wang, C1
Ma, Y1
Kirsch, SH1
Herrmann, W1
Rabagny, Y1
Obeid, R1
Wagner, C1
Luka, Z1
Jentzmik, F1
Stephan, C1
Lein, M1
Miller, K1
Kamlage, B1
Bethan, B1
Kristiansen, G1
Jung, K1
Cavaliere, B1
Macchione, B1
Monteleone, M1
Naccarato, A1
Sindona, G1
Tagarelli, A1
Jiang, X1
Sidhu, R1
Porter, FD1
Yanjanin, NM1
Speak, AO1
te Vruchte, DT1
Platt, FM1
Fujiwara, H1
Scherrer, DE1
Dietzen, DJ1
Schaffer, JE1
Ory, DS1
Wu, H1
Liu, T1
Ma, C1
Xue, R1
Deng, C1
Zeng, H1
Shen, X1
Meyer, TE1
Fox, SD1
Issaq, HJ1
Xu, X1
Chu, LW1
Veenstra, TD1
Hsing, AW1
Cao, Y1
Johnson, HM1
Bazemore-Walker, CR1
Tsuruoka, K1
Tsuneoka, H1
Kawano, M1
Yanagihara, M1
Nojima, J1
Tanaka, T1
Yamamoto, M1
Ichihara, K1
Erdenebaatar, J1
Bayarsaikhan, B1
Yondondorj, A1
Watarai, M1
Shirahata, T1
Jargalsaikhan, E1
Kawamoto, K1
Makino, S1
Lesarri, A1
Cocinero, EJ1
López, JC1
Alonso, JL1
Thomson, CG1
Duncan, K1
Fletcher, SR1
Huscroft, IT1
Pillai, G1
Raubo, P1
Smith, AJ1
Stead, D1
Allan, L1
Leith, JL1
Papakosta, M1
Morrow, JA1
Irving, NG1
McFerran, BW1
Clark, AG1
Liu, J1
Liang, Y1
Ren, F1
Kippert, F1
Laryea, MD1
Steinhagen, F1
Pawliczek, S1
Wendel, U1
Johnson, DW1

Reviews

1 review available for sarcosine and Sensitivity and Specificity

ArticleYear
[New challenges and earlier approved methods in the laboratory diagnosis of prostate cancer].
    Magyar onkologia, 2014, Volume: 58, Issue:4

    Topics: Antigens, Neoplasm; Biomarkers, Tumor; Biopsy; Digital Rectal Examination; Early Detection of Cancer

2014

Trials

1 trial available for sarcosine and Sensitivity and Specificity

ArticleYear
Hyperhydration Effect on Pharmacokinetic Parameters and Detection Sensitivity of Recombinant Human Erythropoietin in Urine and Serum Doping Control Analysis of Males.
    Journal of pharmaceutical sciences, 2019, Volume: 108, Issue:6

    Topics: Acrylic Resins; Adult; Doping in Sports; Electrophoresis, Polyacrylamide Gel; Erythropoietin; Feasib

2019

Other Studies

30 other studies available for sarcosine and Sensitivity and Specificity

ArticleYear
Identification of Sarcosine as a Target Molecule for the Canine Olfactory Detection of Prostate Carcinoma.
    Scientific reports, 2018, 03-21, Volume: 8, Issue:1

    Topics: Animals; Dogs; Feasibility Studies; Humans; Male; Prostatic Neoplasms; Sarcosine; Sensitivity and Sp

2018
SARCOSYL-PAGE: Optimized Protocols for the Separation and Immunological Detection of PEGylated Proteins.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1855

    Topics: Electrophoresis, Polyacrylamide Gel; Erythropoietin; Humans; Immunoblotting; Isoelectric Focusing; P

2019
A highly sensitive DNA aptamer-based fluorescence assay for sarcosine detection down to picomolar levels.
    International journal of biological macromolecules, 2019, May-15, Volume: 129

    Topics: Aptamers, Nucleotide; Biological Assay; Biosensing Techniques; Fluorescence; Humans; Nucleic Acid Co

2019
Sensitive determination of the potential biomarker sarcosine for prostate cancer by LC-MS with N,N'-dicyclohexylcarbodiimide derivatization.
    Journal of separation science, 2014, Volume: 37, Issue:1-2

    Topics: Biomarkers; Chromatography, High Pressure Liquid; Dicyclohexylcarbodiimide; Humans; Isomerism; Male;

2014
Plasma metabolite profiles of Alzheimer's disease and mild cognitive impairment.
    Journal of proteome research, 2014, May-02, Volume: 13, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arachidonic Acid; Biomarkers; Chromatography, Liquid; Co

2014
Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:4

    Topics: Acetylcarnitine; Adolescent; Adult; Africa, Western; Aged; Aged, 80 and over; alpha-Fetoproteins; Bi

2014
Paramagnetic nanoparticles as a platform for FRET-based sarcosine picomolar detection.
    Scientific reports, 2015, Mar-09, Volume: 5

    Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Cell Line, Tumor; Dextrans; Fluorescence Resonance Energy

2015
A case control study of sarcosine as an early prostate cancer detection biomarker.
    BMC urology, 2015, Oct-01, Volume: 15

    Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Early Detection of Cancer; Humans; Male; Middle Aged; Pr

2015
Recombinase polymerase amplification (RPA) combined with lateral flow (LF) strip for equipment-free detection of Cryptosporidium spp. oocysts in dairy cattle feces.
    Parasitology research, 2016, Volume: 115, Issue:9

    Topics: Animals; Cattle; Cattle Diseases; Cryptosporidiosis; Cryptosporidium; DNA, Protozoan; Feces; Nucleic

2016
NMR spectroscopy of filtered serum of prostate cancer: A new frontier in metabolomics.
    The Prostate, 2016, Volume: 76, Issue:12

    Topics: Aged; Biomarkers, Tumor; Biopsy; Citric Acid; Diagnosis, Differential; Digital Rectal Examination; G

2016
Inter- and intra-individual variations of urinary endogenous metabolites in healthy male college students using (1)H NMR spectroscopy.
    Clinical chemistry and laboratory medicine, 2009, Volume: 47, Issue:2

    Topics: Adult; Analysis of Variance; Carboxylic Acids; Health; Humans; Ketoglutaric Acids; Magnetic Resonanc

2009
Evaluation of procedures for outer membrane isolation from Campylobacter jejuni.
    Microbiology (Reading, England), 2009, Volume: 155, Issue:Pt 3

    Topics: Bacterial Outer Membrane Proteins; Campylobacter jejuni; Centrifugation, Density Gradient; Electroph

2009
Quantitative determination of sarcosine and related compounds in urinary samples by liquid chromatography with tandem mass spectrometry.
    Analytical chemistry, 2010, Nov-01, Volume: 82, Issue:21

    Topics: Adolescent; Adult; Aged; Chromatography, Liquid; Creatine; Humans; Male; Metabolomics; Middle Aged;

2010
Quantification of acetylcholine, choline, betaine, and dimethylglycine in human plasma and urine using stable-isotope dilution ultra performance liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Dec-15, Volume: 878, Issue:32

    Topics: Acetylcholine; Adult; Betaine; Choline; Chromatography, High Pressure Liquid; Drug Stability; Female

2010
Sarcosine, folate metabolism and prostate cancer--is there a link?
    The Journal of urology, 2011, Volume: 185, Issue:2

    Topics: Biomarkers, Tumor; Case-Control Studies; Folic Acid; Humans; Male; Neoplasm Invasiveness; Neoplasm S

2011
Sarcosine in prostate cancer tissue is not a differential metabolite for prostate cancer aggressiveness and biochemical progression.
    The Journal of urology, 2011, Volume: 185, Issue:2

    Topics: Aged; Analysis of Variance; Biomarkers, Tumor; Biopsy, Needle; Cohort Studies; Diagnosis, Differenti

2011
Sarcosine as a marker in prostate cancer progression: a rapid and simple method for its quantification in human urine by solid-phase microextraction-gas chromatography-triple quadrupole mass spectrometry.
    Analytical and bioanalytical chemistry, 2011, Volume: 400, Issue:9

    Topics: Adult; Gas Chromatography-Mass Spectrometry; Humans; Male; Prostatic Neoplasms; Sarcosine; Sensitivi

2011
A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma.
    Journal of lipid research, 2011, Volume: 52, Issue:7

    Topics: Adolescent; Adult; Calibration; Case-Control Studies; Child; Child, Preschool; Cholestanols; Chromat

2011
GC/MS-based metabolomic approach to validate the role of urinary sarcosine and target biomarkers for human prostate cancer by microwave-assisted derivatization.
    Analytical and bioanalytical chemistry, 2011, Volume: 401, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Gas Chromatography-Mass Spectrometry; Humans; Mal

2011
A reproducible and high-throughput HPLC/MS method to separate sarcosine from α- and β-alanine and to quantify sarcosine in human serum and urine.
    Analytical chemistry, 2011, Jul-15, Volume: 83, Issue:14

    Topics: Aged; Alanine; beta-Alanine; Chromatography, High Pressure Liquid; Humans; Male; Mass Spectrometry;

2011
Improved enrichment and proteomic identification of outer membrane proteins from a Gram-negative bacterium: focus on Caulobacter crescentus.
    Proteomics, 2012, Volume: 12, Issue:2

    Topics: Bacterial Outer Membrane Proteins; Blotting, Western; Carbonates; Caulobacter crescentus; Chromatogr

2012
Evaluation of IgG ELISA using N-lauroyl-sarcosine-soluble proteins of Bartonella henselae for highly specific serodiagnosis of cat scratch disease.
    Diagnostic microbiology and infectious disease, 2012, Volume: 74, Issue:3

    Topics: Adult; Antibodies, Bacterial; Antigens, Bacterial; Bacterial Proteins; Bartonella henselae; Cat-Scra

2012
Epidemiological and serological survey of brucellosis in Mongolia by ELISA using sarcosine extracts.
    Microbiology and immunology, 2004, Volume: 48, Issue:8

    Topics: Animal Husbandry; Animals; Animals, Domestic; Antibodies, Bacterial; Antigens, Bacterial; Brucella a

2004
Gas-phase structure of N,N-dimethylglycine.
    Chemphyschem : a European journal of chemical physics and physical chemistry, 2005, Aug-12, Volume: 6, Issue:8

    Topics: Gases; Hydrogen Bonding; Models, Chemical; Molecular Structure; Rotation; Sarcosine; Sensitivity and

2005
Sarcosine based indandione hGlyT1 inhibitors.
    Bioorganic & medicinal chemistry letters, 2006, Mar-01, Volume: 16, Issue:5

    Topics: Glycine Plasma Membrane Transport Proteins; Humans; Inhibitory Concentration 50; Molecular Structure

2006
Development of a novel high-throughput assay for the investigation of GlyT-1b neurotransmitter transporter function.
    Combinatorial chemistry & high throughput screening, 2006, Volume: 9, Issue:1

    Topics: Animals; CHO Cells; Cricetinae; Dimethyl Sulfoxide; Fluorescent Dyes; Glycine; Glycine Plasma Membra

2006
Use of sodium lauroyl sarcosinate in a high-sensitivity protein assay by resonance light scattering technique.
    Journal of biomolecular screening, 2006, Volume: 11, Issue:4

    Topics: Animals; Cattle; gamma-Globulins; Hemoglobins; Humans; Light; Ovalbumin; Proteins; Reference Standar

2006
A rapid permeabilization procedure for accurate quantitative determination of beta-galactosidase activity in yeast cells.
    FEMS microbiology letters, 1995, May-01, Volume: 128, Issue:2

    Topics: beta-Galactosidase; Cell Membrane Permeability; Detergents; Saccharomyces; Saccharomyces cerevisiae;

1995
Simple method for the routine determination of betaine and N,N-dimethylglycine in blood and urine.
    Clinical chemistry, 1998, Volume: 44, Issue:9

    Topics: Adult; Betaine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Infant; Middl

1998
Analysis of alcohols, as dimethylglycine esters, by electrospray ionization tandem mass spectrometry.
    Journal of mass spectrometry : JMS, 2001, Volume: 36, Issue:3

    Topics: Alcohols; Betaine; Esters; Imidazoles; Sarcosine; Sensitivity and Specificity; Spectrometry, Mass, E

2001