Page last updated: 2024-08-07 12:49:25
Thermolysin
[no definition available]
Synonyms
EC 3.4.24.27;
Thermostable neutral proteinase
Research
Bioassay Publications (9)
Timeframe | Studies on this Protein(%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (44.44) | 18.2507 |
2000's | 3 (33.33) | 29.6817 |
2010's | 2 (22.22) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Compounds (13)
Drugs with Inhibition Measurements
Drugs with Other Measurements
Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
oxyquinoline | Bacillus thermoproteolyticus | Km | 1,576.4000 | 1 | 1 |
Development of new hydrogen-bond descriptors and their application to comparative molecular field analyses.Journal of medicinal chemistry, , Apr-11, Volume: 45, Issue:8, 2002
Ortho-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors.Journal of medicinal chemistry, , Feb-14, Volume: 40, Issue:4, 1997
Definition and display of steric, hydrophobic, and hydrogen-bonding properties of ligand binding sites in proteins using Lee and Richards accessible surface: validation of a high-resolution graphical tool for drug design.Journal of medicinal chemistry, , May-15, Volume: 35, Issue:10, 1992
Hydroxamic acids as potent inhibitors of endothelin-converting enzyme from human bronchiolar smooth muscle.Journal of medicinal chemistry, , Jun-09, Volume: 38, Issue:12, 1995
Definition and display of steric, hydrophobic, and hydrogen-bonding properties of ligand binding sites in proteins using Lee and Richards accessible surface: validation of a high-resolution graphical tool for drug design.Journal of medicinal chemistry, , May-15, Volume: 35, Issue:10, 1992