Page last updated: 2024-08-07 12:49:25
Thermolysin
[no definition available]
Synonyms
EC 3.4.24.27;
Thermostable neutral proteinase
Research
Bioassay Publications (9)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (13)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 1,10-phenanthroline | Bacillus thermoproteolyticus | IC50 | 360.0000 | 1 | 1 |
| oxyquinoline | Bacillus thermoproteolyticus | IC50 | 350.0000 | 1 | 2 |
| oxyquinoline | Bacillus thermoproteolyticus | Ki | 214.0000 | 1 | 1 |
| thiorphan | Bacillus thermoproteolyticus | IC50 | 9.5000 | 1 | 1 |
| thiorphan | Bacillus thermoproteolyticus | Ki | 1.8098 | 2 | 2 |
| beta-thujaplicin | Bacillus thermoproteolyticus | IC50 | 61.0000 | 1 | 1 |
| tropolone | Bacillus thermoproteolyticus | IC50 | 71.1000 | 1 | 1 |
| carbobenzoxyphenylalanine, (dl-phe)-isomer | Bacillus thermoproteolyticus | Ki | 512.8610 | 1 | 1 |
| kelatorphan | Bacillus thermoproteolyticus | IC50 | 0.0030 | 1 | 1 |
| retrothiorphan | Bacillus thermoproteolyticus | Ki | 2.2909 | 1 | 1 |
| phosphoramidon | Bacillus thermoproteolyticus | IC50 | 0.0330 | 1 | 1 |
| phosphoramidon | Bacillus thermoproteolyticus | Ki | 0.0280 | 1 | 1 |
| 3-phenyl-2-(trifluoromethyl)quinazolin-4(3h)-one | Bacillus thermoproteolyticus | IC50 | 0.0115 | 1 | 1 |
| 3-phenyl-2-(trifluoromethyl)quinazolin-4(3h)-one | Bacillus thermoproteolyticus | Ki | 0.0115 | 1 | 1 |
| 3-(isopropylideneamino)-2,2-dimethyl-2,3-dihydroquinazolin-4(1h)-one | Bacillus thermoproteolyticus | IC50 | 0.2477 | 1 | 1 |
| 3-(isopropylideneamino)-2,2-dimethyl-2,3-dihydroquinazolin-4(1h)-one | Bacillus thermoproteolyticus | Ki | 0.2430 | 1 | 1 |
| thiorphan | Bacillus thermoproteolyticus | IC50 | 1.8000 | 1 | 1 |
| thiorphan | Bacillus thermoproteolyticus | Ki | 1.8000 | 1 | 1 |
| N(2)-([biphenyl]-4-ylsulfonyl)-N-hydroxy-N(2)-isopropoxy-D-valinamide | Bacillus thermoproteolyticus | IC50 | 608.0000 | 2 | 2 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| oxyquinoline | Bacillus thermoproteolyticus | Km | 1,576.4000 | 1 | 1 |