Page last updated: 2024-10-22

albuterol and Sensitivity and Specificity

albuterol has been researched along with Sensitivity and Specificity in 128 studies

Albuterol: A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
albuterol : A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"Air-flow standardized breath sounds were recorded at the chest and at the trachea during histamine challenge test and after subsequent bronchodilation in 12 asthmatics and 6 healthy controls for spectral analysis, to be compared with simultaneous changes in spirometric variables."7.69Changes in frequency spectra of breath sounds during histamine challenge test in adult asthmatics and healthy control subjects. ( Haahtela, T; Katila, T; Malmberg, LP; Paajanen, E; Piirilä, P; Sovijärvi, AR, 1994)
"To compare hyperpolarized helium-3 ((3) He) and xenon-129 ((129) Xe) MRI in asthmatics before and after salbutamol inhalation."5.17Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation. ( Kirby, M; Leary, D; Maksym, GN; McCormack, DG; Parraga, G; Starr, D; Svenningsen, S; Wheatley, A, 2013)
"In critically ill adult patients, nebulized albuterol and ipratropium does not cause significant tachycardia or tachyarrhythmias."5.15Effects of nebulized bronchodilator therapy on heart rate and arrhythmias in critically ill adult patients. ( Barber, KR; Khorfan, FM; Smith, P; Watt, S, 2011)
"On separate study days, 15 nonsmokers with mild asthma received randomized nominal albuterol doses of 0 to 576 microg by using specially manufactured MDI canisters."5.10A methacholine challenge dose-response study for development of a pharmacodynamic bioequivalence methodology for albuterol metered- dose inhalers. ( Adams, WP; Creticos, PS; Khattignavong, AP; Lewis, LD; Lietman, PS; Martinez, MN; Molzon, JA; Petty, BG; Singh, GJ; Williams, RL, 2002)
"Overall, this review supports the equivalence of continuous and intermittent albuterol nebulization in the treatment of acute adult asthma."4.81Continuous vs intermittent beta-agonists in the treatment of acute adult asthma: a systematic review with meta-analysis. ( Rodrigo, C; Rodrigo, GJ, 2002)
"Airway responsiveness to histamine, diurnal peak-flow variability, and bronchodilator reversibility cannot be used interchangeably as objective markers of asthma in epidemiologic studies."3.73Recognition of asthma in adolescents and young adults: which objective measure is best? ( Backer, V; Postma, DS; Ulrik, CS, 2005)
"Air-flow standardized breath sounds were recorded at the chest and at the trachea during histamine challenge test and after subsequent bronchodilation in 12 asthmatics and 6 healthy controls for spectral analysis, to be compared with simultaneous changes in spirometric variables."3.69Changes in frequency spectra of breath sounds during histamine challenge test in adult asthmatics and healthy control subjects. ( Haahtela, T; Katila, T; Malmberg, LP; Paajanen, E; Piirilä, P; Sovijärvi, AR, 1994)
"Significant cough is the most reliable antecedent of wheezing during an RTI."2.74Signs and symptoms that precede wheezing in children with a pattern of moderate-to-severe intermittent wheezing. ( Bacharier, LB; Camera, LJ; Chinchilli, VM; Paul, IM; Phillips, BR; Rivera-Spoljaric, K; Strunk, RC; Taussig, LM; Zeiger, RS, 2009)
"Ten patients with COPD, mechanically ventilated on volume-controlled mode, received 6 puffs of salbutamol (S, 100 micrograms/puff)."2.70Duration of salbutamol-induced bronchodilation delivered by metered-dose inhaler in mechanically ventilated COPD patients. ( Georgopoulos, D; Kafetzakis, A; Kondili, E; Maliotakis, C; Mouloudi, E, 2001)
" The patients attended the laboratory during both treatment periods at 0730 hours, when a dose-response curve for systemic beta2-adrenoceptor responses to inhaled salbutamol (0."2.69Concomitant inhaled corticosteroid resensitises cardiac beta2-adrenoceptors in the presence of long-acting beta2-agonist therapy. ( Aziz, I; Lipworth, BJ; McFarlane, LC, 1998)
" Regression analysis also showed no evidence of a dose-response relationship for Ros."2.67Measurement of normal human airways response to beta-adrenoceptor stimulation using a forced oscillation technique. ( Clark, RA; Lipworth, BJ; McDevitt, DG, 1991)
"Patients with COPD using ≥1."1.40A simple rule to identify patients with chronic obstructive pulmonary disease who may need treatment reevaluation. ( Altan, AE; Altman, PR; Colice, GL; Donohue, JF; Hanania, NA; Kurlander, JL; Rodriguez-Roisin, R; Sharafkhaneh, A, 2014)
"A sensitive and selective liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) was developed and validated for the determination of salbutamol in human plasma and urine, and successfully applied to the pharmacokinetic study of salbutamol in Chinese healthy volunteers after inhalation of salbutamol sulfate aerosol."1.38Determination of salbutamol in human plasma and urine using liquid chromatography coupled to tandem mass spectrometry and its pharmacokinetic study. ( Chen, K; Guo, R; Liu, S; Liu, X; Teng, Y; Wang, B; Wei, C; Yuan, G; Zhang, D; Zhang, R, 2012)
" This method has been successfully applied to the pharmacokinetic study of compound ipratropium bromide aerosol mainly containing ipratropium bromide (IB) and salbutamol sulphate (SS) after inhalation in rats."1.37Simultaneous determination of ipratropium and salbutamol in rat plasma by LC-MS/MS and its application to a pharmacokinetic study. ( Ding, C; Ge, Q; Li, Z; Wu, J; Zhi, X; Zhou, Z, 2011)
"Six patients with bronchial asthma and 12 patients with mild COPD."1.33Acute electrophysiologic effects of inhaled salbutamol in humans. ( Kallergis, EM; Kanoupakis, EM; Klapsinos, NK; Manios, EG; Mavrakis, HE; Schiza, SE; Vardas, PE, 2005)
"Of 516 cases, 54."1.33High resolution CT and bronchial reversibility test for diagnosing COPD. ( Hoshi, T; Kanauchi, T; Kanazawa, M; Kurashima, K; Sato, N; Sugita, Y; Takayanagi, N; Tokunaga, D; Ubukata, M; Yanagisawa, T, 2005)
"Three different methods developed for the determination of salbutamol sulfate (SBS), in pure drug form and in dosage forms, are discussed."1.32Three useful bromimetric methods for the determination of salbutamol sulfate. ( Basavaiah, K; Prameela, HC, 2003)
"In 22 patients with COPD, the presence of expiratory flow limitation was assessed with patients in the sitting and supine positions using the negative expiratory pressure technique, and the effects of heliox (80% He, 20% O2) on breathing pattern, expiratory flow limitation, and dynamic hyperinflation, evaluated from the change in inspiratory capacity (IC), were measured at rest and were compared with those due to inhaled salbutamol."1.32Effect of heliox breathing on dynamic hyperinflation in COPD patients. ( D'Angelo, E; Foresi, A; Milic-Emili, J; Pecchiari, M; Pelucchi, A, 2004)
"Albuterol delivery was 3."1.32Albuterol delivery from a metered-dose inhaler with spacer is reduced following short-duration manual ventilation in a neonatal ventilator-lung model. ( Ballard, J; Lugo, RA, 2004)
"Tremor was measured using a laser pointer technique."1.32Tremor side effects of salbutamol, quantified by a laser pointer technique. ( Broeders, ME; Folgering, HT; Nizet, TA, 2004)
" However, in view of the steep bronchodilator dose-response curve for salbutamol, further studies are needed to determine whether such device care is clinically necessary."1.32Effect of mouthpiece washing on aerosol performance of CFC-free Ventolin. ( Bosnic-Anticevich, SZ; Chan, HK; Chew, NY; Reddel, HK, 2004)
"Twenty-three subjects with latex allergy (history and positive skin test response, positive serologic test response, or both) and 3 atopic control subjects not allergic to latex (history and negative skin test response, negative serologic test response, or both) were sequentially exposed to air, control cornstarch, and then progressive 2-fold increments of LACs in a single-masked fashion."1.31A hooded exposure chamber method for semiquantitative latex aeroallergen challenge. ( Adkinson, NF; Hamilton, RG; Kurtz, KM; Schaefer, JA, 2001)
"Albuterol is a beta2-adrenergic agonist commonly used as a bronchodilator for the treatment of patients with asthma."1.30Determination of albuterol in plasma after aerosol inhalation by gas chromatography-mass spectrometry with selected-ion monitoring. ( Anderson, P; Breen, P; Compadre, CM; Gann, L; Hiller, C; Logsdon, TW; Zhou, X, 1997)
"In order to obtain pharmacokinetic data from studies in humans, a sensitive and selective assay for the quantification of salbutamol in human plasma samples was required."1.30Rapid pharmacokinetic screening of salbutamol in plasma samples by column-switching high-performance liquid chromatography-electrospray mass spectrometry. ( Sauter, T; Schmeer, K; Schmid, J, 1997)

Research

Studies (128)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's34 (26.56)18.2507
2000's69 (53.91)29.6817
2010's24 (18.75)24.3611
2020's1 (0.78)2.80

Authors

AuthorsStudies
Yao, X1
Parnot, C1
Deupi, X1
Ratnala, VR1
Swaminath, G1
Farrens, D1
Kobilka, B1
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Sakellariou, P1
Petrou, M1
Lyris, E1
Tsivou, M1
Fragkaki, A1
Kiousi, P1
Angelis, YS1
Pistos, C1
Svenningsen, S1
Kirby, M1
Starr, D1
Leary, D1
Wheatley, A1
Maksym, GN1
McCormack, DG1
Parraga, G1
Garrido, BC1
Silva, ML1
Borges, RM1
Padilha, MC1
de Aquino Neto, FR1
Yan, Z1
Hu, T1
Guo, W1
Deng, A1
Di, J1
Sharafkhaneh, A1
Altan, AE1
Colice, GL1
Hanania, NA1
Donohue, JF1
Kurlander, JL1
Rodriguez-Roisin, R1
Altman, PR1
Trotta, T1
Guerra, L1
Piro, D1
d'Apolito, M1
Piccoli, C1
Porro, C1
Giardino, I1
Lepore, S1
Castellani, S1
Di Gioia, S1
Petrella, A1
Maffione, AB1
Casavola, V1
Capitanio, N1
Conese, M1
Lei, Y1
Li, X2
Akash, MS1
Zhou, L1
Tang, X1
Shi, W1
Liu, Z1
Chen, S1
Batmaz, SB1
Kuyucu, S1
Arıkoglu, T1
Tezol, O1
Aydogdu, A1
Czövek, D1
Shackleton, C1
Hantos, Z1
Taylor, K1
Kumar, A1
Chacko, A1
Ware, RS1
Makan, G1
Radics, B1
Gingl, Z1
Sly, PD1
Fruchter, O1
Yigla, M1
Al Obaidi, AH1
Al Samarai, AM1
Lei, YC1
Tsai, YF1
Tai, YT1
Lin, CY1
Hsieh, KH1
Chang, TH1
Sheu, SY1
Kuo, TF1
Sirichai, S1
Khanatharana, P1
Zheng, L1
Tong, P1
Zheng, X1
Chi, Y1
Chen, G2
Zhang, L1
Richter, DC1
Joubert, JR1
Nell, H1
Schuurmans, MM1
Irusen, EM1
Rivera-Spoljaric, K1
Chinchilli, VM2
Camera, LJ1
Zeiger, RS1
Paul, IM1
Phillips, BR1
Taussig, LM1
Strunk, RC1
Bacharier, LB1
Zhang, LY1
Chang, BY1
Dong, T1
He, PL1
Yang, WJ1
Wang, ZY1
Mazhar, SH1
Chrystyn, H1
Di Corcia, D1
Morra, V1
Pazzi, M1
Vincenti, M1
Tilemann, L1
Gindner, L1
Meyer, FJ1
Laux, G1
Szecsenyi, J1
Schneider, A1
Pérez-de-Llano, LA1
Carballada, F1
Castro Añón, O1
Pizarro, M1
Golpe, R1
Baloira, A1
Vázquez Caruncho, M1
Boquete, M1
Axén, J1
Malmström, D1
Axelsson, BO1
Petersson, P1
Sjöberg, PJ1
Li, C1
Wu, YL1
Yang, T1
Zhang, Y1
Huang-Fu, WG1
Duffy, MJ1
Mullan, BA1
Craig, TR1
Shyamsundar, M1
MacSweeney, RE1
Thompson, G1
Stevenson, M1
McAuley, DF1
Nie, J1
Zhu, M1
Lian, J1
Pan, Y1
Deng, X1
Hu, C1
Wang, G1
Li, Y1
Wang, X1
Guo, Q1
Wu, J2
Xi, C1
Li, Z2
Lee, KM1
Kim, HJ1
Jeong, ES1
Yoo, HH1
Kwon, OS1
Jin, C1
Kim, DH1
Lee, J1
Khorfan, FM1
Smith, P1
Watt, S1
Barber, KR1
Ding, C1
Ge, Q1
Zhou, Z1
Zhi, X1
Miravitlles, M1
Llor, C1
Calvo, E1
Diaz, S1
Díaz-Cuervo, H1
Gonzalez-Rojas, N1
Sidler-Moix, AL1
Mercier, T1
Decosterd, LA1
Di Paolo, ER1
Berger-Gryllaki, M1
Cotting, J1
Pannatier, A1
Zhang, D1
Teng, Y1
Chen, K1
Liu, S2
Wei, C1
Wang, B1
Yuan, G1
Zhang, R1
Liu, X1
Guo, R1
Silvestro, L1
Savu, SR1
Savu, SN1
Tudoroniu, A1
Tarcomnicu, I1
Yan, H1
Wang, R1
Han, Y1
Ciprandi, G1
Tosca, MA1
Capasso, M1
Rodrigo, GJ1
Rodrigo, C1
Chhabra, SK2
Vijayan, VK1
Gupta, R1
De, S1
Pizzichini, E1
Pizzichini, MM1
Leigh, R1
Djukanović, R1
Sterk, PJ1
Duarte, M1
Camargos, P1
Creticos, PS1
Adams, WP1
Petty, BG1
Lewis, LD1
Singh, GJ1
Khattignavong, AP1
Molzon, JA1
Martinez, MN1
Lietman, PS1
Williams, RL1
Dirikolu, L1
Mollett, BA1
Troppmann, A1
Woods, WE1
Bratton, C1
Cashman, CP1
Schroedter, D1
Mayer, B1
Lehner, AF1
Karpiesiuk, W1
Hughes, C1
Boyles, J1
Harkins, JD1
Tobin, T1
Koh, YM1
Saleh, MI1
Tan, SC1
Basavaiah, K1
Prameela, HC1
Meyts, I1
Proesmans, M1
De Boeck, K1
Hadjikoumi, I1
Hassan, A1
Milner, AD2
Pecchiari, M1
Pelucchi, A1
D'Angelo, E2
Foresi, A1
Milic-Emili, J2
Lugo, RA1
Ballard, J1
Miyamoto, M1
Tomaki, M1
Lötvall, J1
Lindén, A1
Hart, SP1
Nizet, TA1
Broeders, ME1
Folgering, HT1
Ezzahir, N1
Leske, V1
Peiffer, C1
Trang, H1
Parker, AL1
Chew, NY1
Reddel, HK1
Bosnic-Anticevich, SZ1
Chan, HK1
Dundas, I1
Chan, EY1
Bridge, PD2
McKenzie, SA1
Butz, AM1
Donithan, M1
Bollinger, ME1
Rand, C1
Thompson, RE1
Kallergis, EM1
Manios, EG1
Kanoupakis, EM1
Schiza, SE1
Mavrakis, HE1
Klapsinos, NK1
Vardas, PE1
Kurashima, K1
Takayanagi, N1
Sato, N1
Kanauchi, T1
Hoshi, T1
Tokunaga, D1
Ubukata, M1
Yanagisawa, T1
Sugita, Y1
Kanazawa, M1
Almeida, VK1
Larive, CK1
Duan, J1
Chen, H1
Chen, Y1
Huang, Y1
Ulrik, CS1
Postma, DS1
Backer, V1
Thomas, MR1
Rafferty, GF1
Blowes, R1
Peacock, JL1
Marlow, N1
Calvert, S1
Milner, A1
Greenough, A1
Kirschvink, N1
Leemans, J1
Delvaux, F1
Snaps, F1
Clercx, C1
Gustin, P1
Zhang, J1
Xu, Y1
Di, X1
Wu, M1
Bourdin, A1
Paganin, F1
Préfaut, C1
Kieseler, D1
Godard, P1
Chanez, P1
Wei, S1
Guo, H1
Lin, JM1
Scott, S1
Fuld, JP1
Carter, R1
McEntegart, M1
MacFarlane, NG1
Maniadakis, N1
Tzanakis, N1
Fragoulakis, V1
Hatzikou, M1
Siafakas, N1
Cápka, V1
Carter, SJ1
Perry, R1
Joseph, MX1
De Pasquale, CG1
Chew, DP1
Yiu, D1
Aylward, PE1
Mangoni, AA1
Merkus, PJ1
MacLeod, SL1
Sudhir, P1
Wong, CS1
Stern, T1
Garg, A1
Dawson, N1
McFadden, ER1
Galant, SP1
Morphew, T1
Amaro, S1
Liao, O1
Boonsarngsuk, V1
Wangsuppasawad, N1
Kiatboonsri, S1
Kiatboonsri, C1
Choothakan, S1
Zerah, F1
Lorino, AM1
Lorino, H2
Harf, A2
Macquin-Mavier, I1
Yiallouros, PK1
Tsai, CE1
Kondo, F1
Pellicer Ciscar, C1
Perpiña Tordera, M1
de Diego Damia, A1
Macián Gisbert, V1
Pou, K1
Ong, H2
Adam, A2
Lamothe, P1
Delahaut, P1
Collins, S2
O'Keeffe, M2
Smyth, MR1
Howells, L1
Godfrey, M1
Sauer, MJ1
Hyland, ME1
Kenyon, CA1
Jacobs, PA1
Gautrin, D1
D'Aquino, LC1
Gagnon, G1
Malo, JL1
Cartier, A1
Colthup, PV1
Young, GC1
Felgate, CC1
Kesten, S1
Rebuck, AS1
Malmberg, LP1
Sovijärvi, AR1
Paajanen, E1
Piirilä, P1
Haahtela, T1
Katila, T1
Connett, GJ1
Lenney, W1
van Rhijn, JA1
Heskamp, HH1
Altria, KD1
Polettini, A1
Montagna, M1
Segura, J2
de la Torre, X2
Lee, H1
Silverman, M1
Van Vyncht, G1
Preece, S1
Gaspar, P1
Maghuin-Rogister, G1
DePauw, E1
Couper, FJ1
Drummer, OH1
Schuh, S1
Johnson, D1
Stephens, D1
Callahan, S1
Canny, G1
Logsdon, TW1
Zhou, X1
Breen, P1
Anderson, P1
Gann, L1
Hiller, C1
Compadre, CM1
Schmeer, K1
Sauter, T1
Schmid, J1
Aziz, I1
McFarlane, LC1
Lipworth, BJ2
Tantucci, C1
Duguet, A1
Similowski, T1
Zelter, M1
Derenne, JP1
Schleufe, P1
Reiffen, HP1
Piepenbrock, S1
Bergés, R1
Ventura, R1
Piérart, F1
Wildhaber, JH1
Vrancken, I1
Devadason, SG1
Le Souëf, PN1
Elliott, CT1
Baxter, GA1
Hewitt, SA1
Arts, CJ1
van Baak, M1
Hellenäs, KE1
Johannson, A1
Rutten-van Mölken, M1
Roos, B1
Van Noord, JA1
Biddlecombe, RA1
Pleasance, S1
Loss, JR1
Orzechowski, RF1
Hock, RS1
Delacourt, C1
Herve-Guillot, M1
Reinert, P1
Housset, B1
Aboul-Enein, HY1
Surmeian, M1
Kurtz, KM2
Hamilton, RG2
Schaefer, JA2
Adkinson, NF2
Leone, FT1
Mauger, EA1
Peters, SP1
Fish, JE1
Boushey, HA1
Cherniack, RM1
Drazen, JM1
Fahy, JV1
Ford, J1
Israel, E1
Lazarus, SC1
Lemanske, RF1
Martin, RJ1
McGeady, SJ1
Sorkness, C1
Szefler, SJ1
Panicker, J1
Sethi, GR1
Sehgal, V1
Naidong, W1
Shou, W1
Chen, YL1
Jiang, X1
Desai, MY1
De la Peña-Almaguer, E1
Mannting, F1
Primeau, MN1
García-Ruiz, C1
Marina, ML1
Higton, DM1
Mouloudi, E1
Maliotakis, C1
Kondili, E1
Kafetzakis, A1
Georgopoulos, D1
Mallmann, F1
Fernandes, AK1
Avila, EM1
Nogueira, FL1
Steinhorst, AM1
Saucedo, DZ1
Machado, FJ1
Raymundi, MG1
Dalcin, PT1
Menna Barreto, SS1
Dyer, CA1
Singh, SJ1
Stockley, RA1
Sinclair, AJ1
Hill, SL1
Walsh-Kelly, CM1
Hennes, HM1
Anklecha, MU1
Beydon, N1
Amsallem, F1
Bellet, M1
Boule, M1
Chaussain, M1
Denjean, A1
Matran, R1
Wuyam, B1
Alberti, C1
Gaultier, C1
Degroodt, JM1
Wyhowski de Bukanski, B1
Srebrnik, S1
Wassermann, K1
Pothoff, G1
Bahra, J1
Hilger, HH1
Clark, RA1
McDevitt, DG1
Gravel, A1
Messier, J1
Bellemare, M1
Lantin, F1
Sauvé, G1
Tyssen, P1

Clinical Trials (14)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"A Two-arm, Placebo-controlled Randomized Clinical Trial to Evaluate the Effect of Dupilumab on Airway Hyper-responsiveness and Ventilation Heterogeneity in Patients With Asthma With a T2 Immune Signature"[NCT03884842]Phase 324 participants (Actual)Interventional2019-07-01Completed
FUNLUM: Functional Lung MRI for Early Treatment Response Assessment and Outcome Prediction for Patients With Severe Eosinophilic Asthma on Anti IL 5 Antibody Therapy[NCT04512521]40 participants (Anticipated)Observational2020-05-04Recruiting
Single-centre Study Exploring the Utility of Hyperpolarized 129Xe Magnetic Resonance Imaging in Healthy Volunteers and Patients With Lung Disease[NCT03455686]60 participants (Anticipated)Interventional2018-04-19Recruiting
Changes of Pulmonary Function, Voice and Swallowing Symptoms After Total Parathyroidectomy for Secondary Hyperparathyroidism in the Presence of Intact Recurrent Laryngeal Nerve[NCT04267965]48 participants (Actual)Observational [Patient Registry]2017-08-01Completed
Prospective Trial of Effect of Nebulized Bronchodilators on Heart Rate and Arrhythmias in Critically Ill Adult Patients[NCT01151579]Phase 489 participants (Actual)Interventional2008-12-31Completed
A Pilot Study to Evaluate the Dose-response of Inhaled Formoterol to Inhibit Airway Responsiveness to Methacholine in Patients With Mild Asthma[NCT00643578]37 participants (Actual)Interventional2008-03-31Completed
[NCT00575445]100 participants (Anticipated)Observational2007-11-30Terminated (stopped due to Nitric Oxide analyzer not functioning properly)
A Prospective Observational Study in a Tertiary Pediatric Hospital in Beijing to Understand the Accuracy of Bronchodilator Response (BDR) in Chinese Controller Naive Asthmatic Children Between the Age of 4~12 Years Old[NCT01500525]587 participants (Actual)Observational2011-12-31Completed
Nebulizer Intervention for Minority Children With Asthma[NCT00218816]Phase 3221 participants (Actual)Interventional2000-08-31Completed
Functional Evaluation of Distal Airways by Forced Oscillations: Diagnosis Help in Bronchiolitis Obliterans Syndrome in Post Bone Marrow Transplantation[NCT02902471]110 participants (Actual)Interventional2011-06-30Completed
The Effects of Dynamic Neuromuscular Stabilization Approach on Functional Movement Patterns, Balance, Quality of Life, and Exercise Capacity in Older Patients With Chronic Nonspecific Low Back Pain[NCT04948073]72 participants (Actual)Interventional2021-06-24Completed
A Novel Method to Measure Diaphragmatic Motion and Excursion[NCT03225508]175 participants (Anticipated)Observational2017-08-01Recruiting
Diagnostic Accuracy Of Forced Oscillation Technique To Detect Lung Function Anomalies[NCT04006964]579 participants (Actual)Observational2018-10-18Completed
Asthma Clinical Research Network (ACRN)[NCT00000577]Phase 30 participants (Actual)Interventional1993-09-30Withdrawn (stopped due to Record is an ACRN grant summary & not reflective of an individual trial. All ACTs conducted by ACRN were individually registered on the PRS.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Arrhythmias

Any new arrhythmia documented in the medical record that occurred between breathing treatments. (NCT01151579)
Timeframe: 15 minutes after each treatment for average of 3 to 5 days

Interventionpercent (Number)
Nebulized Albuterol 2.5mg0.33
Levalbuterol 1.251.3

Heart Rate in Beats Per Minute

Average difference in Heart rate between pre and post breathing treatments (NCT01151579)
Timeframe: Five days

Interventionbpm (Mean)
Nebulized Albuterol 2.5mg-0.16
Levalbuterol 1.251.40

Total Number of Participants With Arrhythmias

Documented new arrhythmia occurring during study. (NCT01151579)
Timeframe: Five days

Interventionparticipants (Number)
Nebulized Albuterol 2.5mg2
Levalbuterol 1.253

FEV1

The forced expiratory volume in the first second, expressed as a percent predicted. (NCT00643578)
Timeframe: 1 hour after dose

Interventionpercent predicted (Mean)
12 Mcg of Formoterol88
24 Mcg of Formoterol91

Post-dose PC20

The PC20 is the provocational dose of methacholine causing a 20% drop in forced expiratory volume in the first second. (NCT00643578)
Timeframe: 3-7 days after visits 1 and 2

Interventionmg/mL (Geometric Mean)
12 Mcg Formoterol7
24 Mcg Formoterol16

Bronchodilator Response in Asthmatic Children

"To observe bronchodilator response(BDR) distribution curve for Chinese non-asthmatic children from 4-12 years, BDR calculated as: (FEV 1 L post-bronchodilator - FEV 1 L pre-bronchodilator)/FEV 1 L pre-bronchodilator × 100%.~To observe BDR distribution curve for Chinese controller-naïve asthmatic children from 4-12 years~To compare BDR values between non-asthmatic group and controller-naïve asthmatic group, and analyze appropriate cut-off point value" (NCT01500525)
Timeframe: 3 years

Interventionpercentage of BDR (Mean)
Asthmatic Children9.45
Non-asthmatic Children3.30

Reviews

2 reviews available for albuterol and Sensitivity and Specificity

ArticleYear
Continuous vs intermittent beta-agonists in the treatment of acute adult asthma: a systematic review with meta-analysis.
    Chest, 2002, Volume: 122, Issue:1

    Topics: Administration, Inhalation; Adult; Albuterol; Asthma; Bronchodilator Agents; Confidence Intervals; D

2002
Safety of sputum induction.
    The European respiratory journal. Supplement, 2002, Volume: 37

    Topics: Administration, Inhalation; Albuterol; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage;

2002

Trials

21 trials available for albuterol and Sensitivity and Specificity

ArticleYear
Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 38, Issue:6

    Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Bronchodilator Agents; Contrast Me

2013
Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 38, Issue:6

    Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Bronchodilator Agents; Contrast Me

2013
Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 38, Issue:6

    Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Bronchodilator Agents; Contrast Me

2013
Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 38, Issue:6

    Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Bronchodilator Agents; Contrast Me

2013
Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 38, Issue:6

    Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Bronchodilator Agents; Contrast Me

2013
Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 38, Issue:6

    Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Bronchodilator Agents; Contrast Me

2013
Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 38, Issue:6

    Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Bronchodilator Agents; Contrast Me

2013
Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 38, Issue:6

    Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Bronchodilator Agents; Contrast Me

2013
Hyperpolarized (3) He and (129) Xe MRI: differences in asthma before bronchodilation.
    Journal of magnetic resonance imaging : JMRI, 2013, Volume: 38, Issue:6

    Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Bronchodilator Agents; Contrast Me

2013
Signs and symptoms that precede wheezing in children with a pattern of moderate-to-severe intermittent wheezing.
    The Journal of pediatrics, 2009, Volume: 154, Issue:6

    Topics: Acetates; Adult; Albuterol; Anti-Asthmatic Agents; Asthenia; Bronchodilator Agents; Budesonide; Caus

2009
Exhaled nitric oxide predicts control in patients with difficult-to-treat asthma.
    The European respiratory journal, 2010, Volume: 35, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Albuterol; Androstadienes; Anti-Asthmatic Agents; Anxiety; Ast

2010
Effects of nebulized bronchodilator therapy on heart rate and arrhythmias in critically ill adult patients.
    Chest, 2011, Volume: 140, Issue:6

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Albuterol; Analysis of Variance; Arrhyth

2011
Efficacy and safety of a home-made non-valved spacer for bronchodilator therapy in acute asthma.
    Acta paediatrica (Oslo, Norway : 1992), 2002, Volume: 91, Issue:9

    Topics: Acute Disease; Administration, Inhalation; Adolescent; Albuterol; Asthma; Child; Child, Preschool; C

2002
A methacholine challenge dose-response study for development of a pharmacodynamic bioequivalence methodology for albuterol metered- dose inhalers.
    The Journal of allergy and clinical immunology, 2002, Volume: 110, Issue:5

    Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Asthma; Bayes Th

2002
Apparent ELISA detection times for albuterol after administration with the torpex equine inhaler device.
    Veterinary therapeutics : research in applied veterinary medicine, 2002,Fall, Volume: 3, Issue:3

    Topics: Administration, Inhalation; Aerosols; Albuterol; Animals; Bronchodilator Agents; Cross Reactions; Do

2002
Effects of respiratory timing and cheek support on resistance measurements, before and after bronchodilation in asthmatic children using the interrupter technique.
    Pediatric pulmonology, 2003, Volume: 36, Issue:6

    Topics: Adolescent; Airway Resistance; Albuterol; Asthma; Bronchial Provocation Tests; Bronchodilator Agents

2003
Relevance of a portable spirometer for detection of small airways obstruction.
    Pediatric pulmonology, 2005, Volume: 39, Issue:2

    Topics: Administration, Inhalation; Adolescent; Airway Obstruction; Albuterol; Bronchodilator Agents; Child;

2005
Monitoring nebulizer use in children: comparison of electronic and asthma diary data.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2005, Volume: 94, Issue:3

    Topics: Administration, Inhalation; Albuterol; Anti-Asthmatic Agents; Asthma; Child; Child, Preschool; Femal

2005
[Contribution of the bronchodilator test in the study of bronchial reversibility].
    Archivos de bronconeumologia, 1994, Volume: 30, Issue:10

    Topics: Adult; Albuterol; Asthma; Bronchi; Bronchial Provocation Tests; Bronchitis; Diagnosis, Differential;

1994
Sensitivity of quality of life domains and constructs to longitudinal change in a clinical trial comparing salmeterol with placebo in asthmatics.
    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 1994, Volume: 3, Issue:2

    Topics: Activities of Daily Living; Adrenergic beta-Agonists; Adult; Aged; Albuterol; Asthma; Double-Blind M

1994
Hospitalization patterns in severe acute asthma in children.
    Pediatric pulmonology, 1997, Volume: 23, Issue:3

    Topics: Administration, Inhalation; Adolescent; Albuterol; Asthma; Bronchodilator Agents; Child; Child, Pres

1997
Concomitant inhaled corticosteroid resensitises cardiac beta2-adrenoceptors in the presence of long-acting beta2-agonist therapy.
    European journal of clinical pharmacology, 1998, Volume: 54, Issue:5

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Bronchodilator Agents; Budes

1998
Effect of salbutamol on dynamic hyperinflation in chronic obstructive pulmonary disease patients.
    The European respiratory journal, 1998, Volume: 12, Issue:4

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aged; Albuterol; Expiratory Reserve Volume; Fe

1998
Effective application of bronchodilator aerosols from metered-dose inhalers (MDI) via resuscitator-bag and adapter.
    Resuscitation, 1998, Volume: 39, Issue:3

    Topics: Administration, Inhalation; Aerosols; Airway Resistance; Albuterol; Asthma; Bronchodilator Agents; E

1998
An empirical comparison of the St George's Respiratory Questionnaire (SGRQ) and the Chronic Respiratory Disease Questionnaire (CRQ) in a clinical trial setting.
    Thorax, 1999, Volume: 54, Issue:11

    Topics: Adult; Aged; Albuterol; Bronchodilator Agents; Double-Blind Method; Feasibility Studies; Female; Hum

1999
Comparative efficiency of commercial and improvised spacer device in acute bronchial asthma.
    Indian pediatrics, 2001, Volume: 38, Issue:4

    Topics: Administration, Inhalation; Albuterol; Asthma; Child; Child, Preschool; Dose-Response Relationship,

2001
Duration of salbutamol-induced bronchodilation delivered by metered-dose inhaler in mechanically ventilated COPD patients.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2001, Volume: 56, Issue:3

    Topics: Administration, Inhalation; Aged; Airway Resistance; Albuterol; Analysis of Variance; Bronchodilator

2001
The incremental shuttle walking test in elderly people with chronic airflow limitation.
    Thorax, 2002, Volume: 57, Issue:1

    Topics: Administration, Inhalation; Aged; Aged, 80 and over; Albuterol; Asthma; Bronchodilator Agents; Drug

2002
Measurement of normal human airways response to beta-adrenoceptor stimulation using a forced oscillation technique.
    Journal of clinical pharmacy and therapeutics, 1991, Volume: 16, Issue:3

    Topics: Adrenergic beta-Agonists; Adult; Albuterol; Analysis of Variance; Dose-Response Relationship, Drug;

1991

Other Studies

105 other studies available for albuterol and Sensitivity and Specificity

ArticleYear
Coupling ligand structure to specific conformational switches in the beta2-adrenoceptor.
    Nature chemical biology, 2006, Volume: 2, Issue:8

    Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Alprenolol; Amino Acid Sequence; Binding Sites; Crys

2006
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Determination of salmeterol, α-hydroxysalmeterol and fluticasone propionate in human urine and plasma for doping control using UHPLC-QTOF-MS.
    Biomedical chromatography : BMC, 2021, Volume: 35, Issue:8

    Topics: Albuterol; Chromatography, High Pressure Liquid; Doping in Sports; Fluticasone; Humans; Linear Model

2021
Salbutamol extraction from urine and its stability in different solutions: identification of methylation products and validation of a quantitative analytical method.
    Biomedical chromatography : BMC, 2013, Volume: 27, Issue:12

    Topics: Albuterol; Chemical Fractionation; Drug Stability; Gas Chromatography-Mass Spectrometry; Humans; Hyd

2013
A label-free immunosensor for determination of salbutamol based on localized surface plasmon resonance biosensing.
    Bioprocess and biosystems engineering, 2014, Volume: 37, Issue:4

    Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Gold; Liver; Metal Nanoparticles; Sensitivi

2014
A simple rule to identify patients with chronic obstructive pulmonary disease who may need treatment reevaluation.
    Respiratory medicine, 2014, Volume: 108, Issue:9

    Topics: Adrenergic beta-2 Receptor Agonists; Aged; Albuterol; Bronchodilator Agents; Comorbidity; Databases,

2014
Stimulation of β2-adrenergic receptor increases CFTR function and decreases ATP levels in murine hematopoietic stem/progenitor cells.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2015, Volume: 14, Issue:1

    Topics: Adenosine Triphosphate; Albuterol; Analysis of Variance; Animals; Biomarkers; Cells, Cultured; Chlor

2015
Development of analytical method for ultrasensitive detection of salbutamol utilizing DNA labeled-immunoprobe.
    Journal of pharmaceutical and biomedical analysis, 2015, Mar-25, Volume: 107

    Topics: Albuterol; Antibodies; DNA; Humans; Immunoassay; Limit of Detection; Polymerase Chain Reaction; Sens

2015
Impulse oscillometry in acute and stable asthmatic children: a comparison with spirometry.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2016, Volume: 53, Issue:2

    Topics: Adolescent; Albuterol; Asthma; Child; Female; Forced Expiratory Volume; Humans; Male; Oscillometry;

2016
Tidal changes in respiratory resistance are sensitive indicators of airway obstruction in children.
    Thorax, 2016, Volume: 71, Issue:10

    Topics: Airway Resistance; Albuterol; Anthropometry; Asthma; Bronchodilator Agents; Child; Child, Preschool;

2016
Response to bronchodilators after exercise challenge predicts bronchial hyperreactivity.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2008, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Albuterol; Bayes Theorem; Bronchial Hyperreactivity; Bronchial Provocation Tests;

2008
Biochemical markers as a response guide for steroid therapy in asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2008, Volume: 45, Issue:5

    Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Beclomethasone; Biomarkers; Breath

2008
Development and fast screening of salbutamol residues in swine serum by an enzyme-linked immunosorbent assay in Taiwan.
    Journal of agricultural and food chemistry, 2008, Jul-23, Volume: 56, Issue:14

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Enzyme-Linked Immunosorbent Assay; Gas Chromatography-

2008
Rapid analysis of clenbuterol, salbutamol, procaterol, and fenoterol in pharmaceuticals and human urine by capillary electrophoresis.
    Talanta, 2008, Sep-15, Volume: 76, Issue:5

    Topics: Adrenergic beta-Agonists; Albuterol; Buffers; Clenbuterol; Electrophoresis, Capillary; Fenoterol; Hu

2008
Electrostacking online sample pre-concentration capillary electrophoresis with amperometric detection for beta2-agonists in human urine.
    Journal of separation science, 2008, Volume: 31, Issue:20

    Topics: Adrenergic beta-Agonists; Albuterol; Clenbuterol; Electrodes; Electrophoresis, Capillary; Ethanolami

2008
Diagnostic value of post-bronchodilator pulmonary function testing to distinguish between stable, moderate to severe COPD and asthma.
    International journal of chronic obstructive pulmonary disease, 2008, Volume: 3, Issue:4

    Topics: Administration, Inhalation; Albuterol; Asthma; Bronchodilator Agents; Diagnosis, Differential; Femal

2008
Simultaneous determination of salbutamol, ractopamine, and clenbuterol in animal feeds by SPE and LC-MS.
    Journal of chromatographic science, 2009, Volume: 47, Issue:4

    Topics: Acetonitriles; Adrenergic beta-Agonists; Albuterol; Animal Feed; Chromatography, Liquid; Clenbuterol

2009
New HPLC assay for urinary salbutamol concentrations in samples collected post-inhalation.
    Journal of pharmaceutical and biomedical analysis, 2009, Sep-08, Volume: 50, Issue:2

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Chromatography, High Pressure Liquid;

2009
Simultaneous determination of beta2-agonists in human urine by fast-gas chromatography/mass spectrometry: method validation and clinical application.
    Biomedical chromatography : BMC, 2010, Volume: 24, Issue:4

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Asthma; Gas Chromatography

2010
[Diagnostic value of peak flow variability in patients with suspected diagnosis of bronchial asthma in general practice].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:41

    Topics: Albuterol; Asthma; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; Di

2009
Efforts to improve detection sensitivity for capillary electrophoresis coupled to atmospheric pressure photoionization mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2010, May-15, Volume: 24, Issue:9

    Topics: Albuterol; Electrophoresis, Capillary; Mass Spectrometry; Nicotine; Procainamide; Sensitivity and Sp

2010
Simultaneous determination of clenbuterol, salbutamol and ractopamine in milk by reversed-phase liquid chromatography tandem mass spectrometry with isotope dilution.
    Journal of chromatography. A, 2010, Dec-10, Volume: 1217, Issue:50

    Topics: Albuterol; Animals; Chromatography, Reverse-Phase; Clenbuterol; Deuterium; Drug Residues; Drug Stabi

2010
Impaired endothelium-dependent vasodilatation is a novel predictor of mortality in intensive care.
    Critical care medicine, 2011, Volume: 39, Issue:4

    Topics: Aged; Albuterol; Confidence Intervals; Endothelium, Vascular; Female; Hospital Mortality; Humans; In

2011
[Determination of fifteen beta-agonists in animal urine by high performance liquid chromatography-tandem mass spectrometry].
    Se pu = Chinese journal of chromatography, 2010, Volume: 28, Issue:8

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Chromatography, High Pressure Liquid; Clenbuterol; Sen

2010
Preparation and characterization of an immunoaffinity column for the selective extraction of salbutamol from pork sample.
    Journal of chromatographic science, 2011, Volume: 49, Issue:4

    Topics: Albuterol; Animals; Antibodies, Immobilized; Chromatography, Affinity; Drug Residues; Immunosorbent

2011
Simple and accurate quantitative analysis of seven prohibited threshold substances in human urine by liquid chromatography/tandem mass spectrometry in doping control.
    Rapid communications in mass spectrometry : RCM, 2011, Aug-30, Volume: 25, Issue:16

    Topics: Albuterol; Chromatography, Liquid; Doping in Sports; Epitestosterone; Humans; Morphine; Propanolamin

2011
Simultaneous determination of ipratropium and salbutamol in rat plasma by LC-MS/MS and its application to a pharmacokinetic study.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Nov-15, Volume: 879, Issue:30

    Topics: Acetates; Albuterol; Animals; Area Under Curve; Chromatography, Liquid; Drug Stability; Ipratropium;

2011
[Validation of the Spanish version of the Chronic Obstructive Pulmonary Disease-Population Screener (COPD-PS). Its usefulness and that of FEV₁/FEV₆ for the diagnosis of COPD].
    Medicina clinica, 2012, Nov-17, Volume: 139, Issue:12

    Topics: Aged; Albuterol; Area Under Curve; Bronchodilator Agents; Cross-Sectional Studies; Female; Forced Ex

2012
A highly sensitive LC-tandem MS assay for the measurement in plasma and in urine of salbutamol administered by nebulization during mechanical ventilation in healthy volunteers.
    Biomedical chromatography : BMC, 2012, Volume: 26, Issue:5

    Topics: Administration, Inhalation; Adult; Albuterol; Chromatography, High Pressure Liquid; Drug Stability;

2012
Determination of salbutamol in human plasma and urine using liquid chromatography coupled to tandem mass spectrometry and its pharmacokinetic study.
    Biomedical chromatography : BMC, 2012, Volume: 26, Issue:10

    Topics: Acetaminophen; Adult; Albuterol; Area Under Curve; Chromatography, Reverse-Phase; Drug Stability; Hu

2012
Development of a sensitive method for simultaneous determination of fluticasone propionate and salmeterol in plasma samples by liquid chromatography-tandem mass spectrometry.
    Biomedical chromatography : BMC, 2012, Volume: 26, Issue:5

    Topics: Albuterol; Androstadienes; Chromatography, Liquid; Drug Stability; Fluticasone; Humans; Linear Model

2012
Screening, recognition and quantitation of salbutamol residues in ham sausages by molecularly imprinted solid phase extraction coupled with high-performance liquid chromatography-ultraviolet detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Jul-01, Volume: 900

    Topics: Adsorption; Albuterol; Animals; Chromatography, High Pressure Liquid; Drug Residues; Food Analysis;

2012
High exhaled nitric oxide levels may predict bronchial reversibility in allergic children with asthma or rhinitis.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2013, Volume: 50, Issue:1

    Topics: Adolescent; Albuterol; Asthma; Breath Tests; Child; Cohort Studies; Cross-Sectional Studies; Female;

2013
Expression of bronchodilator response: comparison of four indices.
    Respiratory medicine, 2002, Volume: 96, Issue:8

    Topics: Adult; Albuterol; Asthma; Bronchodilator Agents; Bronchospirometry; Female; Forced Expiratory Volume

2002
Selective extraction of salbutamol from human plasma with the use of phenylboronic acid.
    Journal of chromatography. A, 2003, Feb-14, Volume: 987, Issue:1-2

    Topics: Adrenergic beta-Agonists; Albuterol; Boronic Acids; Calibration; Humans; Reference Standards; Refere

2003
Three useful bromimetric methods for the determination of salbutamol sulfate.
    Analytical and bioanalytical chemistry, 2003, Volume: 376, Issue:6

    Topics: Albuterol; Capsules; Kinetics; Pharmaceutical Preparations; Sensitivity and Specificity; Spectrophot

2003
Exhaled nitric oxide corresponds with office evaluation of asthma control.
    Pediatric pulmonology, 2003, Volume: 36, Issue:4

    Topics: Albuterol; Asthma; Breath Tests; Bronchodilator Agents; Child; Female; Forced Expiratory Volume; Hum

2003
Effect of heliox breathing on dynamic hyperinflation in COPD patients.
    Chest, 2004, Volume: 125, Issue:6

    Topics: Aged; Airway Resistance; Albuterol; Bronchodilator Agents; Female; Helium; Humans; Inspiratory Capac

2004
Albuterol delivery from a metered-dose inhaler with spacer is reduced following short-duration manual ventilation in a neonatal ventilator-lung model.
    Respiratory care, 2004, Volume: 49, Issue:9

    Topics: Administration, Inhalation; Airway Resistance; Albuterol; Bronchodilator Agents; Dose-Response Relat

2004
Beta-adrenoceptor stimulation and neutrophil accumulation in mouse airways.
    The European respiratory journal, 2004, Volume: 24, Issue:2

    Topics: Administration, Intranasal; Airway Resistance; Albuterol; Animals; Bronchoalveolar Lavage Fluid; Che

2004
Additive blockade of beta2-integrin adhesion of eosinophils by salmeterol and fluticasone propionate.
    The European respiratory journal, 2004, Volume: 24, Issue:2

    Topics: Albuterol; Androstadienes; Apoptosis; CD18 Antigens; Cell Survival; Cells, Cultured; Eosinophils; Fl

2004
Tremor side effects of salbutamol, quantified by a laser pointer technique.
    Respiratory medicine, 2004, Volume: 98, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albuterol; Asthma; Bronchodilator Agents; Child; Child,

2004
Airway reactivity is a determinant of bronchodilator responsiveness after methacholine-induced bronchoconstriction.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2004, Volume: 41, Issue:6

    Topics: Administration, Inhalation; Adolescent; Adult; Albuterol; Asthma; Bronchial Hyperreactivity; Bronchi

2004
Effect of mouthpiece washing on aerosol performance of CFC-free Ventolin.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2004, Volume: 41, Issue:7

    Topics: Administration, Inhalation; Aerosols; Albuterol; Analysis of Variance; Anti-Asthmatic Agents; Asthma

2004
Diagnostic accuracy of bronchodilator responsiveness in wheezy children.
    Thorax, 2005, Volume: 60, Issue:1

    Topics: Administration, Inhalation; Albuterol; Asthma; Bronchodilator Agents; Child; Child, Preschool; Femal

2005
Acute electrophysiologic effects of inhaled salbutamol in humans.
    Chest, 2005, Volume: 127, Issue:6

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Asthma; Atrioventricular Node; Dose

2005
High resolution CT and bronchial reversibility test for diagnosing COPD.
    Respirology (Carlton, Vic.), 2005, Volume: 10, Issue:3

    Topics: Administration, Inhalation; Aged; Albuterol; Bronchial Provocation Tests; Bronchodilator Agents; Fem

2005
Acute bronchodilator response has limited value in differentiating bronchial asthma from COPD.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2005, Volume: 42, Issue:5

    Topics: Administration, Inhalation; Adult; Aged; Albuterol; Area Under Curve; Asthma; Bronchodilator Agents;

2005
Insights into cyclodextrin interactions during sample stacking using capillary isotachophoresis with on-line microcoil NMR detection.
    Magnetic resonance in chemistry : MRC, 2005, Volume: 43, Issue:9

    Topics: Albuterol; Alprenolol; Atenolol; Cyclodextrins; Diffusion; Electrolytes; Electrophoresis; Magnetic R

2005
[Simultaneous determination of cimaterol, clenbuterol and salbutamol in feeds by capillary zone electrophoresis].
    Se pu = Chinese journal of chromatography, 2005, Volume: 23, Issue:3

    Topics: Albuterol; Animal Feed; Clenbuterol; Electrophoresis, Capillary; Ethanolamines; Sensitivity and Spec

2005
Recognition of asthma in adolescents and young adults: which objective measure is best?
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2005, Volume: 42, Issue:7

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Anti-Asthmatic Agents; Antigens; Asthma; Bro

2005
Plethysmograph and interrupter resistance measurements in prematurely born young children.
    Archives of disease in childhood. Fetal and neonatal edition, 2006, Volume: 91, Issue:3

    Topics: Airway Obstruction; Airway Resistance; Albuterol; Bronchodilator Agents; Functional Residual Capacit

2006
Non-invasive assessment of airway responsiveness in healthy and allergen-sensitised cats by use of barometric whole body plethysmography.
    Veterinary journal (London, England : 1997), 2007, Volume: 173, Issue:2

    Topics: Albuterol; Allergens; Animals; Antigens, Helminth; Ascaris suum; Bronchoalveolar Lavage Fluid; Bronc

2007
Quantitation of salbutamol in human urine by liquid chromatography-electrospray ionization mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Feb-02, Volume: 831, Issue:1-2

    Topics: Albuterol; Chromatography, High Pressure Liquid; Female; Humans; Male; Reproducibility of Results; S

2006
Nitrogen washout slope in poorly controlled asthma.
    Allergy, 2006, Volume: 61, Issue:1

    Topics: Adolescent; Adult; Albuterol; Asthma; Breath Tests; Bronchodilator Agents; Case-Control Studies; Fem

2006
Chiral separation of salbutamol and bupivacaine by capillary electrophoresis using dual neutral cyclodextrins as selectors and its application to pharmaceutical preparations and rat blood samples assay.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Feb-17, Volume: 832, Issue:1

    Topics: Albuterol; Animals; Buffers; Bupivacaine; Cyclodextrins; Electrophoresis, Capillary; Hydrogen-Ion Co

2006
Diaphragm ultrasonography as an alternative to whole-body plethysmography in pulmonary function testing.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2006, Volume: 25, Issue:2

    Topics: Adrenergic beta-Agonists; Albuterol; Diaphragm; Female; Humans; Linear Models; Male; Middle Aged; Pl

2006
Diaphragm ultrasonography as an alternative to whole-body plethysmography in pulmonary function testing.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2006, Volume: 25, Issue:2

    Topics: Adrenergic beta-Agonists; Albuterol; Diaphragm; Female; Humans; Linear Models; Male; Middle Aged; Pl

2006
Diaphragm ultrasonography as an alternative to whole-body plethysmography in pulmonary function testing.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2006, Volume: 25, Issue:2

    Topics: Adrenergic beta-Agonists; Albuterol; Diaphragm; Female; Humans; Linear Models; Male; Middle Aged; Pl

2006
Diaphragm ultrasonography as an alternative to whole-body plethysmography in pulmonary function testing.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2006, Volume: 25, Issue:2

    Topics: Adrenergic beta-Agonists; Albuterol; Diaphragm; Female; Humans; Linear Models; Male; Middle Aged; Pl

2006
Economic evaluation of tiotropium and salmeterol in the treatment of chronic obstructive pulmonary disease (COPD) in Greece.
    Current medical research and opinion, 2006, Volume: 22, Issue:8

    Topics: Albuterol; Bronchodilator Agents; Computer Simulation; Cost-Benefit Analysis; Drug Therapy, Combinat

2006
Minimizing matrix effects in the development of a method for the determination of salmeterol in human plasma by LC/MS/MS at low pg/mL concentration levels.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Sep-01, Volume: 856, Issue:1-2

    Topics: Adrenergic beta-Agonists; Albuterol; Chromatography, High Pressure Liquid; Humans; Salmeterol Xinafo

2007
High-resolution transthoracic echocardiography of the left anterior descending coronary artery: a novel noninvasive assessment of coronary vasoreactivity.
    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2008, Volume: 21, Issue:2

    Topics: Adult; Albuterol; Cohort Studies; Coronary Circulation; Coronary Vessels; Echocardiography, Transeso

2008
Beclomethasone and albuterol in mild asthma.
    The New England journal of medicine, 2007, Aug-02, Volume: 357, Issue:5

    Topics: Administration, Inhalation; Albuterol; Anti-Asthmatic Agents; Asthma; Beclomethasone; Drug Combinati

2007
Stereoisomer analysis of wastewater-derived beta-blockers, selective serotonin re-uptake inhibitors, and salbutamol by high-performance liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. A, 2007, Nov-02, Volume: 1170, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Albuterol; Canada; Chromatography, High Pressure Liquid; Molecular Stru

2007
Validating a guidelines based asthma decision support system: step one.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2007, Volume: 44, Issue:8

    Topics: Albuterol; Asthma; Bronchodilator Agents; Decision Making, Computer-Assisted; Female; Humans; Male;

2007
Value of the bronchodilator response in assessing controller naïve asthmatic children.
    The Journal of pediatrics, 2007, Volume: 151, Issue:5

    Topics: Albuterol; Asthma; Bronchodilator Agents; Child; Child, Preschool; Female; Forced Expiratory Volume;

2007
A predictive score for unfavorable outcome of acute asthma in the emergency room.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2007, Volume: 90, Issue:10

    Topics: Acute Disease; Albuterol; Asthma; Bronchodilator Agents; Emergency Service, Hospital; Female; Health

2007
Forced oscillation technique vs spirometry to assess bronchodilatation in patients with asthma and COPD.
    Chest, 1995, Volume: 108, Issue:1

    Topics: Airway Resistance; Albuterol; Asthma; Female; Forced Expiratory Volume; Humans; Lung Diseases, Obstr

1995
Effective argon-FRC with a rebreathing technique in children with acute asthma.
    Pediatric pulmonology, 1995, Volume: 19, Issue:1

    Topics: Acute Disease; Administration, Inhalation; Adolescent; Albuterol; Argon; Asthma; Bronchodilator Agen

1995
Liquid chromatographic determination of salbutamol and clenbuterol residues in swine serum and muscle.
    Microbios, 1994, Volume: 80, Issue:325

    Topics: Albuterol; Animals; Chromatography, High Pressure Liquid; Clenbuterol; Drug Residues; Muscles; Sensi

1994
Combined immunoextraction approach coupled to a chemiluminescence enzyme immunoassay for the determination of trace levels of salbutamol and clenbuterol in tissue samples.
    The Analyst, 1994, Volume: 119, Issue:12

    Topics: Albuterol; Animals; Antibodies, Monoclonal; Cattle; Chromatography, Affinity; Clenbuterol; Cross Rea

1994
Multi-residue analysis for beta-agonists in urine and liver samples using mixed phase columns with determination by radioimmunoassay.
    The Analyst, 1994, Volume: 119, Issue:12

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Cattle; Clenbuterol; Drug Residues; Indicators and Rea

1994
Melanin as an adsorbent for drug residues.
    The Analyst, 1994, Volume: 119, Issue:12

    Topics: Adsorption; Albuterol; Animals; Clenbuterol; Diethylstilbestrol; Drug Residues; Melanins; Methods; N

1994
Comparison between peak expiratory flow rates (PEFR) and FEV1 in the monitoring of asthmatic subjects at an outpatient clinic.
    Chest, 1994, Volume: 106, Issue:5

    Topics: Adolescent; Adult; Aged; Albuterol; Ambulatory Care Facilities; Asthma; Female; Forced Expiratory Vo

1994
Determination of salmeterol in rat and dog plasma by high-performance liquid chromatography with fluorescence detection.
    Journal of pharmaceutical sciences, 1993, Volume: 82, Issue:3

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Chromatography, High Pressure Liquid; Dogs; Female; Ma

1993
Is the short-term response to inhaled beta-adrenergic agonist sensitive or specific for distinguishing between asthma and COPD?
    Chest, 1994, Volume: 105, Issue:4

    Topics: Administration, Inhalation; Aged; Albuterol; Asthma; Diagnosis, Differential; Forced Expiratory Volu

1994
Changes in frequency spectra of breath sounds during histamine challenge test in adult asthmatics and healthy control subjects.
    Chest, 1994, Volume: 105, Issue:1

    Topics: Adolescent; Adult; Albuterol; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Forc

1994
Use of pulse oximetry in the hospital management of acute asthma in childhood.
    Pediatric pulmonology, 1993, Volume: 15, Issue:6

    Topics: Acute Disease; Adolescent; Albuterol; Aminophylline; Asthma; Child; Child, Preschool; Female; Hospit

1993
Rapid analysis of beta-agonists in urine by thermospray tandem mass spectrometry.
    Journal of chromatography. A, 1995, Sep-29, Volume: 712, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Cattle; Clenbuterol; Ethanolamine; Ethanolamines; Gas

1995
Application of capillary electrophoresis to pharmaceutical analysis.
    Methods in molecular biology (Clifton, N.J.), 1996, Volume: 52

    Topics: Albuterol; Capillary Action; Chromatography, High Pressure Liquid; Electrophoresis; Pharmaceutical P

1996
Determination of beta 2-agonists in hair by gas chromatography/mass spectrometry.
    Journal of mass spectrometry : JMS, 1996, Volume: 31, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Boron Compounds; Clenbuterol; Doping in Sports; Gas Ch

1996
A portable device based on the interrupter technique to measure bronchodilator response in schoolchildren.
    The European respiratory journal, 1996, Volume: 9, Issue:7

    Topics: Airway Resistance; Albuterol; Asthma; Bronchodilator Agents; Child; Child, Preschool; Female; Humans

1996
Gas and liquid chromatography coupled to tandem mass spectrometry for the multiresidue analysis of beta-agonists in biological matrices.
    Journal of chromatography. A, 1996, Oct-25, Volume: 750, Issue:1-2

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Animals, Domestic; Cattle; Clenbuterol; Drug Residues;

1996
Gas chromatographic-mass spectrometric determination of beta 2-agonists in postmortem blood: application in forensic medicine.
    Journal of chromatography. B, Biomedical applications, 1996, Oct-25, Volume: 685, Issue:2

    Topics: Adrenergic beta-Agonists; Albuterol; Asthma; Autopsy; Calibration; Fenoterol; Forensic Medicine; Gas

1996
Determination of albuterol in plasma after aerosol inhalation by gas chromatography-mass spectrometry with selected-ion monitoring.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, May-09, Volume: 692, Issue:2

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Gas Chromatography-Mass Spectrometry;

1997
Rapid pharmacokinetic screening of salbutamol in plasma samples by column-switching high-performance liquid chromatography-electrospray mass spectrometry.
    Journal of chromatography. A, 1997, Aug-08, Volume: 777, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Calibration; Chromatography, High Pressure Liquid; Female; Huma

1997
Analytical methodology for enantiomers of salbutamol in human urine for application in doping control.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Feb-19, Volume: 723, Issue:1-2

    Topics: Adrenergic beta-Agonists; Albuterol; Bronchodilator Agents; Chromatography, High Pressure Liquid; Do

1999
Washing plastic spacers in household detergent reduces electrostatic charge and greatly improves delivery.
    The European respiratory journal, 1999, Volume: 13, Issue:3

    Topics: Administration, Inhalation; Adult; Albuterol; Detergents; Drug Delivery Systems; Female; Humans; In

1999
Use of biosensors for rapid drug residue analysis without sample deconjugation or clean-up: a possible way forward.
    The Analyst, 1998, Volume: 123, Issue:12

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Biosensing Techniques; Cattle; Drug Residues; Gas Chro

1998
Automated protein precipitation by filtration in the 96-well format.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Nov-12, Volume: 734, Issue:2

    Topics: Albuterol; Animals; Autoanalysis; Blood Proteins; Centrifugation; Chemical Precipitation; Chromatogr

1999
Measurement of albuterol in guinea pig serum by high performance liquid chromatography with fluorescence detection.
    Biomedical chromatography : BMC, 2000, Volume: 14, Issue:1

    Topics: Albuterol; Animals; Bronchodilator Agents; Chromatography, High Pressure Liquid; Guinea Pigs; Reprod

2000
Use of the forced oscillation technique to assess airway obstruction and reversibility in children.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:3 Pt 1

    Topics: Administration, Inhalation; Adolescent; Airway Resistance; Albuterol; Bronchodilator Agents; Child;

2000
Analysis of salbutamol and related impurities by derivative spectrometry.
    Archiv der Pharmazie, 2000, Volume: 333, Issue:4

    Topics: Adrenergic beta-Agonists; Albuterol; Bronchodilator Agents; Chromatography, High Pressure Liquid; Co

2000
A hooded exposure chamber method for semiquantitative latex aeroallergen challenge.
    The Journal of allergy and clinical immunology, 2001, Volume: 107, Issue:1

    Topics: Administration, Inhalation; Adult; Albuterol; Female; Humans; Latex Hypersensitivity; Male; Middle A

2001
The utility of peak flow, symptom scores, and beta-agonist use as outcome measures in asthma clinical research.
    Chest, 2001, Volume: 119, Issue:4

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Area Under Curve; Asthma; False Positive Rea

2001
Novel liquid chromatographic-tandem mass spectrometric methods using silica columns and aqueous-organic mobile phases for quantitative analysis of polar ionic analytes in biological fluids.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Apr-25, Volume: 754, Issue:2

    Topics: Albuterol; Body Fluids; Chromatography, Liquid; Cotinine; Drug Stability; Humans; Mass Spectrometry;

2001
Can pre-treatment with beta-agonists reduce stress test time and the use of atropine in dobutamine stress testing?
    Cardiology, 2001, Volume: 95, Issue:3

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Aged; Albuterol; Atropine; Coronary Disease; D

2001
Repeated latex aeroallergen challenges employing a hooded exposure chamber: safety and reproducibility.
    Allergy, 2001, Volume: 56, Issue:9

    Topics: Administration, Inhalation; Adult; Albuterol; Atmosphere Exposure Chambers; Bronchial Provocation Te

2001
Fast enantiomeric separation of basis drugs by electrokinetic chromatography. Application to the quantitation of terbutaline in a pharmaceutical preparation.
    Electrophoresis, 2001, Volume: 22, Issue:15

    Topics: Albuterol; beta-Cyclodextrins; Bile Acids and Salts; Buffers; Chromatography; Chromatography, Micell

2001
A rapid, automated approach to optimisation of multiple reaction monitoring conditions for quantitative bioanalytical mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2001, Volume: 15, Issue:20

    Topics: Albuterol; Automation; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Mass Spec

2001
Early prediction of poor outcome in patients with acute asthma in the emergency room.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2002, Volume: 35, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Albuterol; Asthma; Bronchodilator Agents; Child; Emergency Service

2002
Do clinical variables predict pathologic radiographs in the first episode of wheezing?
    Pediatric emergency care, 2002, Volume: 18, Issue:1

    Topics: Adolescent; Albuterol; Bronchodilator Agents; Child; Child, Preschool; Discriminant Analysis; Female

2002
Other option in bronchiolitis.
    Indian pediatrics, 2002, Volume: 39, Issue:2

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Albuterol; Bronchiolitis; Child; Child, Prescho

2002
Pre/postbronchodilator interrupter resistance values in healthy young children.
    American journal of respiratory and critical care medicine, 2002, May-15, Volume: 165, Issue:10

    Topics: Airway Resistance; Albuterol; Anthropometry; Bronchodilator Agents; Child, Preschool; Female; Humans

2002
Immunoaffinity-chromatography purification of salbutamol in liver and HPLC-fluorometric detection at trace residue level.
    Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 1992, Volume: 195, Issue:6

    Topics: Albuterol; Animals; Cattle; Chromatography, Affinity; Chromatography, High Pressure Liquid; Drug Res

1992
Reversible volume changes of trapped gas in nonspecific bronchoprovocation tests.
    Chest, 1992, Volume: 101, Issue:4

    Topics: Acetylcholine; Albuterol; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Forced Exp

1992
A competitive enzyme immunoassay for albuterol: its application for the drug screening in urine.
    Journal of immunoassay, 1991, Volume: 12, Issue:2

    Topics: Albuterol; Alkaline Phosphatase; Animals; Antibodies, Monoclonal; Binding, Competitive; Cross Reacti

1991