A protein that is a translation product of the ALOX15 gene in rabbit. [PRO:DAN, UniProtKB:P12530]
12/15-lipoxygenase;
Arachidonate 12-lipoxygenase, leukocyte-type;
12-LOX;
L-12LO;
1.13.11.31;
Arachidonate 15-lipoxygenase;
15-LOX;
1.13.11.33;
Arachidonate omega-6 lipoxygenase;
Erythroid cell-specific 15-lipoxygenase
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| catechol | Oryctolagus cuniculus (rabbit) | IC50 | 0.8680 | 1 | 0 |
| pyrogallol | Oryctolagus cuniculus (rabbit) | IC50 | 2.1140 | 1 | 0 |
| acetaminophen | Oryctolagus cuniculus (rabbit) | IC50 | 28.3800 | 1 | 0 |
| chlorpromazine | Oryctolagus cuniculus (rabbit) | IC50 | 15.9510 | 1 | 0 |
| dipyridamole | Oryctolagus cuniculus (rabbit) | IC50 | 6.9560 | 1 | 0 |
| disulfiram | Oryctolagus cuniculus (rabbit) | IC50 | 16.0660 | 1 | 0 |
| hydralazine | Oryctolagus cuniculus (rabbit) | IC50 | 3.6490 | 1 | 0 |
| indapamide | Oryctolagus cuniculus (rabbit) | IC50 | 2.9180 | 1 | 0 |
| isoproterenol | Oryctolagus cuniculus (rabbit) | IC50 | 1.7700 | 1 | 0 |
| ketoconazole | Oryctolagus cuniculus (rabbit) | IC50 | 5.4250 | 1 | 0 |
| mitoxantrone | Oryctolagus cuniculus (rabbit) | IC50 | 1.7853 | 1 | 0 |
| nifedipine | Oryctolagus cuniculus (rabbit) | IC50 | 15.1010 | 1 | 0 |
| masoprocol | Oryctolagus cuniculus (rabbit) | IC50 | 0.1100 | 1 | 1 |
| propofol | Oryctolagus cuniculus (rabbit) | IC50 | 7.5960 | 1 | 0 |
| tolazamide | Oryctolagus cuniculus (rabbit) | IC50 | 5.1060 | 1 | 0 |
| estriol | Oryctolagus cuniculus (rabbit) | IC50 | 8.6350 | 1 | 0 |
| estrone | Oryctolagus cuniculus (rabbit) | IC50 | 6.5890 | 1 | 0 |
| ethinyl estradiol | Oryctolagus cuniculus (rabbit) | IC50 | 5.6780 | 1 | 0 |
| levodopa | Oryctolagus cuniculus (rabbit) | IC50 | 2.2580 | 1 | 0 |
| n,n'-diphenyl-4-phenylenediamine | Oryctolagus cuniculus (rabbit) | IC50 | 2.8830 | 1 | 0 |
| bisphenol a | Oryctolagus cuniculus (rabbit) | IC50 | 1.3040 | 1 | 0 |
| 2-anisidine | Oryctolagus cuniculus (rabbit) | IC50 | 2.0480 | 1 | 0 |
| phenothiazine | Oryctolagus cuniculus (rabbit) | IC50 | 4.6430 | 1 | 0 |
| phenylhydrazine | Oryctolagus cuniculus (rabbit) | IC50 | 1.6660 | 1 | 0 |
| monobenzone | Oryctolagus cuniculus (rabbit) | IC50 | 4.8920 | 1 | 0 |
| vinblastine | Oryctolagus cuniculus (rabbit) | IC50 | 5.0370 | 1 | 0 |
| 4-octylphenol | Oryctolagus cuniculus (rabbit) | IC50 | 4.0930 | 1 | 0 |
| etoposide | Oryctolagus cuniculus (rabbit) | IC50 | 3.1870 | 1 | 0 |
| dobutamine | Oryctolagus cuniculus (rabbit) | IC50 | 0.5990 | 1 | 0 |
| methyldopa | Oryctolagus cuniculus (rabbit) | IC50 | 2.1260 | 1 | 0 |
| mifepristone | Oryctolagus cuniculus (rabbit) | IC50 | 0.5550 | 1 | 0 |
| nelfinavir | Oryctolagus cuniculus (rabbit) | IC50 | 13.7970 | 1 | 0 |
| isoscopoletin | Oryctolagus cuniculus (rabbit) | IC50 | 15.1000 | 1 | 1 |
| pd 146176 | Oryctolagus cuniculus (rabbit) | IC50 | 2.9133 | 3 | 3 |
| terconazole | Oryctolagus cuniculus (rabbit) | IC50 | 2.4460 | 1 | 0 |
| ferulic acid | Oryctolagus cuniculus (rabbit) | IC50 | 3.9750 | 1 | 0 |
| diethylstilbestrol | Oryctolagus cuniculus (rabbit) | IC50 | 2.9630 | 1 | 0 |
| thioguanine anhydrous | Oryctolagus cuniculus (rabbit) | IC50 | 16.1590 | 1 | 0 |
| quercetin | Oryctolagus cuniculus (rabbit) | IC50 | 18.7150 | 2 | 2 |
| scopoletin | Oryctolagus cuniculus (rabbit) | IC50 | 16.5000 | 1 | 1 |
| 15-keto-5,8,11,13-eicosatetraenoic acid | Oryctolagus cuniculus (rabbit) | IC50 | 50.0000 | 1 | 1 |
| kaempferol | Oryctolagus cuniculus (rabbit) | IC50 | 2.2000 | 1 | 1 |
| genistein | Oryctolagus cuniculus (rabbit) | IC50 | 9.0330 | 1 | 0 |
| 5-oxo-6,8,11,14-eicosatetraenoic acid | Oryctolagus cuniculus (rabbit) | IC50 | 25.0000 | 1 | 1 |
| 13-oxo-9,11-octadecadienoic acid | Oryctolagus cuniculus (rabbit) | IC50 | 100.0000 | 1 | 1 |
| jaspaquinol | Oryctolagus cuniculus (rabbit) | IC50 | 0.3000 | 1 | 1 |
| tannins | Oryctolagus cuniculus (rabbit) | IC50 | 0.2680 | 1 | 0 |
| rifampin | Oryctolagus cuniculus (rabbit) | IC50 | 2.9490 | 1 | 0 |
| olanzapine | Oryctolagus cuniculus (rabbit) | IC50 | 2.7680 | 1 | 0 |