phenylalanine and Sensitivity and Specificity

phenylalanine has been researched along with Sensitivity and Specificity in 119 studies

Research

Studies (119)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.84)18.7374
1990's29 (24.37)18.2507
2000's60 (50.42)29.6817
2010's26 (21.85)24.3611
2020's3 (2.52)2.80

Authors

AuthorsStudies
B, S; B, VR; K, MN; Sharma, H; Yerra, S1
Maugeri, L; Messina, MA; Petralia, S; Puccio, R; Ruggieri, M; Spoto, G1
Akita, T; Furusho, A; Hamase, K; Hsiao, SW; Hsieh, CL; Ide, T; Ishii, C; Konno, R; Lee, CK; Mita, M; Okamura, T; Shimizu, Y1
Dodda, S; Kandhagatla, RN; Makula, A; Polagani, SR1
Ahmad, I; Ashraf, R; Khan, A; Khan, S; Ullah, R1
Jeong, JS; Kim, SK; Park, SR1
Ingenito, L; Parenti, G; Pecce, R; Ruoppolo, M; Scolamiero, E1
Fang, HX; Liu, XY; Yu, LP1
Hattori, T; Ishikawa, A; Ohki, H; Saito, K; Yabe, T; Yoshino, K1
Eisenhower, C; Erlich, P; Ferrari, A; Irvin-Barnwell, EA; Patel, MD; Roda, P; Tang, X1
Chen, JJ; Fu, YY; Huang, H; Li, Q; Liu, Z; Mu, J; Wei, YD; Xie, P; Yang, DY; Zheng, P; Zhou, CJ; Zhou, JJ1
Acevedo, AC; Chardin, H; De Luca Canto, G; Gozal, D; Guerra, EN; Leite, AF1
Bereczky, Z; Boda, Z; Gindele, R; Ilonczai, P; Kovács, B; Marján, E; Muszbek, L; Oláh, Z; Pfliegler, G; Selmeczi, A; Speker, M; Udvari, Á1
Armutlulu, A; Balaram, H; Balasubramanian, S; Bartosh, TJ; Broda, M; Brown, LE; Burroughs, LM; Burrows, F; Cardoso, JR; Carregaro, RL; Cho, J; Cui, Q; Dela Bela, LF; Dias, JM; Dutta, NK; Flowers, ME; Gallo, S; Hari, P; He, R; He, Y; Heimfeld, S; Jia, B; Jin, X; Jin, YJ; Karakousis, PC; Karmakar, T; Kiem, HP; Kreager, DA; Lebedev, D; Li, F; Li, S; Liang, N; Liu, Z; Luo, J; Luo, Y; Mazuquin, BF; Meng, Y; Mosialos, G; Moura, FA; Müller, CR; Naeem, MA; Nagappa, LK; Nguyen, H; Pelegrinelli, AR; Pinn, ML; Prahlada Rao, VS; Pulsipher, MA; Ragan, DT; Richards, J; Roy, S; Sandmaier, BM; Selfe, J; Selim, MA; Shi, J; Shi, X; Staff, J; Storb, R; Storer, BE; Wang, F; Wang, M; Wang, S; Woolfrey, AE; Wright, T; Ylostalo, JH; Zhang, JY; Zhang, ZY; Zheng, K; Zhu, Z1
Borghei, YS; Ganjali, MR; Hosseini, M; Khoobi, M1
Gopalan, AI; Lee, KP; Manesh, KM; Santhosh, P; Uthayakumar, S1
Arteaga, AL; Castells, E; del Río, L; Frómeta, A; García, SM; González, EC; Licourt, T; Martínez, L; Robaina, MS1
Chang, SM; Guo, HS; Kim, JM; Kim, WS2
Boesch, C; Kreis, R; Nuoffer, JM; Zwygart, K1
Fujii, N; Fukutani, S; Kashino, G; Kinashi, Y; Liu, Y; Maruhashi, A; Masunaga, S; Nagata, K; Ono, K; Sakurai, Y; Suzuki, M; Tanaka, H1
Hong, SP; Jeong, JS; Lee, DH; Lee, YM; Sim, HJ; Yoon, HR1
Gu, W; Hu, X; Liang, J; Sun, J; Wen, Z; Xu, Y; Zhao, T1
Anouti, S; Cottet, H; Vandenabeele-Trambouze, O1
Ayar-Kayali, H; Tarhan, L1
Farmakis, G; Grgic, A; Hellwig, D; Ketter, R; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S; Schaefer, A; Steudel, WI1
Cao, KW; Chen, XF; Chu, QC; Li, WL; Tang, WR; Ye, JN; Zhang, DL; Zhang, JB1
Alexiou, GA; Fotopoulos, AD; Kyritsis, AP; Tsiouris, S; Voulgaris, S1
Hofstetter, H; Hofstetter, O; Kassa, T; Undesser, LP1
Hong, SP; Jeong, JS; Kwon, HJ; Lee, YM; Sim, HJ; Yoon, HR1
Cho, SH; Duin, EC; Hong, JW; Jambovane, S; Kim, SK; Yun, JY1
Kirito, K; Koda, AH; Komatsu, N; Morishita, S; Noda, N; Sekiguchi, Y; Tsuneda, S1
Yan, HT; Zhang, K; Zhou, T1
Asai, S; Ishii, Y; Murai, I; Suzuki, S1
Ross, LF1
Allen, LJ; Harrison, RG; Lamb, JD; Li, N1
Baynes, JW; Carson, JA; Enos, RT; Lima, M; Sato, S1
Bührdel, P; Ceglarek, U; Kiess, W; Müller, P; Stach, B; Thiery, J1
Bongaerts, J; Bujnicki, R; Ganpo-Nkwenkwa, E; Gerigk, M; Sprenger, G; Takors, R1
Buhr, HJ; Foitzik, T; Hines, OJ; Hotz, B; Hotz, HG; Reber, HA1
Bandmann, O; Deuschl, G; Goertz, M; Hefter, H; Hoffmann, G; Jost, W; Müller, U; Oertel, W; Zöfel, P; Zschocke, J1
Dale, Y; Ike, J; Mackey, V; Maleque, M; Mushi, R; Nyanda, A1
Alen, M; Keinanen, O; Knuutinen, J; Komi, PV; Lahti, K; Mero, AA; Nykanen, T; Pitkanen, HT1
Hirata, N; Kuriyama, T; Yamawaki, N1
Albright, R; Cobelli, C; Dietz, N; Joyner, M; Nair, KS; Toffolo, G1
Meerman, JH; Orhan, H; Tump, C; Vermeulen, NP; Zappey, H1
Amon, M; Feiden, W; Hellwig, D; Kirsch, CM; Kubuschok, B; Menger, MD; Romeike, BF; Samnick, S1
Aleshin, AN; Matsuda, H; Miyamoto, Y; Ono, M; Ryugo, M; Sawa, Y1
Brown, EM; Conigrave, AD; Delbridge, L; Mun, HC; Quinn, SJ; Wilkinson, M1
Chen, Y; Qiao, F; Yan, H; Yang, G1
Chen, X; He, Z; Liu, X; Zhang, R; Zhao, C; Zhong, D1
Kobori, T; Toda, K; Yoshii, T1
Capodicasa, S; Colaiocco-Ferrante, L; Colecchia, A; Festi, D; Mazzella, G; Portincasa, P; Roda, E; Sandri, L; Simoni, P; Staniscia, T; Vestito, A; Vitacolonna, E1
Oldiges, M; Takors, R1
Iwai, M; Kato, A; Koeda, N; Suzuki, K1
Clifton-Bligh, RJ; Collyer, CA; Conigrave, AD; Culverston, EL; Franks, AH; Mun, HC1
Hellwig, D; Ketter, R; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S; Schaefer, A; Sell, N1
Farnsworth, PB; Lee, ML; Li, L; Paul, UP1
Deng, C; Yin, X; Zhang, L; Zhang, X1
Gu, XF; Han, LS; Qiu, WJ; Ye, J; Zhang, ZX1
Lioe, H; O'Hair, RA1
Ballhausen, D; Baumgartner, M; Blau, N; Bonafé, L; Fiege, B; Fiori, L; Giovannini, M; Meili, D; Thöny, B1
Betti, M; Carlos, R; Cionini, L; de las Heras, LA; Lazzerini, G; Menichetti, L; Pitois, A; Salvatori, PA; Zampolli, A1
Moeini, H; Vallian, S1
Baum, F; Behbehani, AW; Langenbeck, U; Luthe, H; Mench-Hoinowski, A1
Cornelissen, B; De Spiegeleer, B; Dierckx, RA; Kersemans, K; Kersemans, V; Mertens, J; Slegers, G1
De Spiegeleer, B; Kersemans, V; Mertens, J; Slegers, G1
Ahmed, M; Jimenez-Cruz, M; Leone, SR; Peterka, DS; Wilson, KR1
Alifrangis, M; Drakeley, C; Kulkarni, MA; Kweka, E; Lyimo, I; Magesa, S; Malima, R; Matowo, J; Mosha, FW; Peter, J; Rau, ME; Rowland, M; Salanti, A1
Brettel, K; Byrdin, M; Eker, AP; Lukacs, A; Pan, J; Villette, S; Vos, MH1
Dorris, M; Loh, A; Peterson, L; Weiss, DJ1
Asano, Y; Suzuki, M; Tachibana, S1
Abe, R; Hohsaka, T; Iijima, I; Kajihara, D; Komiyama, C; Sisido, M1
Ajami, D; Rebek, J; Schramm, MP; Volonterio, A1
Asano, Y; Cao, R; Fujii, A; Ortiz, P; Shinohara, H; Tachibana, S; Villalonga, R1
Carnley, B; Hammond, E; Herrmann, R; James, I; P'ng, S; Shaw, K1
Chen, Q; Cross, NC; Jones, AV; Lu, P; Silver, RT; Wang, YL1
Mashru, RC; Sankalia, JM; Sankalia, MG; Sutariya, VB1
Matthews, AJ; Pollitt, RJ1
Bauwens, M; Bossuyt, A; Caveliers, V; Kersemans, K; Keyaerts, M; Lahoutte, T; Mertens, J1
Hayashida, O; Ogawa, N; Uchiyama, M1
Boesch, C; Kreis, R; Lutz, T; Pietz, J; Robert-Tissot, L; Vermathen, P1
Dahlsten, E; Korkeala, H; Lindström, M; Somervuo, P1
Hammen, HW; Matthiesen, U; Schadewaldt, P; Wendel, U1
Geiger, R; Miska, W; Monsees, T1
Chace, DH; Hillman, SL; Kahler, SG; Millington, DS; Naylor, EW; Roe, CR1
Bock, D; Diepenbrock, F; Heckler, R; Lubenow, N; Sander, J; Schickling, H1
Denmeade, R; Green, A; Keffler, S1
Colley, CM; Rakhorst, S; Tillyer, CR1
Agarwal, KC; Beylot, M; Brunengraber, H; Soloviev, MV; Yang, D1
Binette, F; Crawford, K; Goetinck, PF; Millán, JL; Weissig, H1
Lehotay, DC; Randell, EW1
Kanno, S; Matsuda, K; Ono, I1
Asano, Y; Cooper, AJ; Fujii, T; Kato, Y; Nakamura, K1
Pronce, T; Tilquin, B1
Fresta, M; Micali, N; Puglisi, G; Trusso, S; Villari, A1
Beierwaltes, W; Froelich, J; Gonin, J; Macfarlane, D; Mangner, T; Shapiro, B; Wieland, D1
Dey, S; Karthikeyan, S; Mitra, SN; Singh, TP1
Fitzpatrick, PF; Rainina, EI; Simonian, AL; Wild, JR1
Leeming, RJ1
Allen, MC; Nocerini, MR; Stafford, CG1
Donner, K; Fyhrquist, N; Hargrave, PA; McDowell, JH; Popp, MP; Smith, WC1
Cipriano, A; Maniara, WM; Powell, ML1
Rehfeld, JF1
Ao, A; Handyside, AH; Ray, PF; Taylor, DM; Winston, RM1
Kohlmueller, D; Mayatepek, E; Schulze, A1
Akaboshi, M; Kinashi, Y; Kobayashi, T; Masunaga, S; Ono, K; Sakurai, Y; Suzuki, M; Takagaki, M1
Fujinari, E; Mohammad, AA; Okorodudu, AO; Petersen, JR1
Fitzpatrick, PF; Rainina, EI; Simonian, AL; Wild, J1
Allué, JA; Grijalba, A; Merlo, SG; Palacios, M; Rivero, A1
Cunningham, G; Currier, RJ; Eastman, JW; Liao, CL; Lorey, F; Sherwin, JE; Wong, R1
Färkkilä, M; Kallio, M; Kulvik, M; Laakso, J; Ruokonen, I; Vähätalo, J; Zilliacus, R1
Stringham, RW; Ye, YK1
Hobo, T; Qiu, J; Uchiyama, K; Xu, W1
Baloy, A; Fernández, L; Frómeta, A; Torres, E1
Abraham, DG; Cooper, AJ1
Ledley, FD1
Burmester, JG; Clemens, PC; Neumann, SJ; Wulke, AP1
Hummel, W; Koppelkamm, M; Langenbeck, U; Sander, J; Wendel, U1

Reviews

3 review(s) available for phenylalanine and Sensitivity and Specificity

ArticleYear
Diagnostic capability of salivary biomarkers in the assessment of head and neck cancer: A systematic review and meta-analysis.
    Oral oncology, 2015, Volume: 51, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Carbocysteine; Choline; Head and Neck Neoplasms; Humans; Interleukin-8; Middle Aged; Phenylalanine; Piperidines; Saliva; Sensitivity and Specificity; Young Adult

2015
Immusorba TR and PH.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2003, Volume: 7, Issue:1

    Topics: Absorption; Acetylcholine; Arthritis, Rheumatoid; Autoantibodies; Biocompatible Materials; Clinical Trials as Topic; Equipment Design; Equipment Safety; Guillain-Barre Syndrome; Humans; Immunosorbent Techniques; Immunosorbents; Lupus Erythematosus, Systemic; Myasthenia Gravis; Phenylalanine; Sensitivity and Specificity; Tryptophan

2003
Clinical application of genotypic diagnosis for phenylketonuria: theoretical considerations.
    European journal of pediatrics, 1991, Volume: 150, Issue:11

    Topics: Genotype; Humans; Mutation; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Sensitivity and Specificity

1991

Trials

4 trial(s) available for phenylalanine and Sensitivity and Specificity

ArticleYear
The phenylalanine loading test in the differential diagnosis of dystonia.
    Neurology, 2003, Feb-25, Volume: 60, Issue:4

    Topics: Administration, Oral; Adult; Diagnosis, Differential; Dystonia; Female; Humans; Levodopa; Male; Middle Aged; Phenylalanine; Predictive Value of Tests; Reference Values; Sensitivity and Specificity; Time Factors; Tyrosine

2003
Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
    World journal of gastroenterology, 2005, Jan-07, Volume: 11, Issue:1

    Topics: Acetamides; Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Breath Tests; Carbon Isotopes; Female; Hepatitis, Chronic; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Phenylalanine; Prognosis; Sensitivity and Specificity

2005
Validation of brain tumour imaging with p-[123I]iodo-L-phenylalanine and SPECT.
    European journal of nuclear medicine and molecular imaging, 2005, Volume: 32, Issue:9

    Topics: Adult; Aged; Brain Neoplasms; Female; Humans; Male; Middle Aged; Phenylalanine; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon

2005
Atomic emission method for total boron in blood during neutron-capture therapy.
    Clinical chemistry, 2001, Volume: 47, Issue:10

    Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Female; Hematocrit; Humans; Indicators and Reagents; Male; Mass Spectrometry; Middle Aged; Phenylalanine; Sensitivity and Specificity; Spectrophotometry, Atomic

2001

Other Studies

112 other study(ies) available for phenylalanine and Sensitivity and Specificity

ArticleYear
A novel stability-indicating HPLC method for the determination of enantiomeric purity of eluxadoline drug: Amylose tris(3,5-dichlorophenyl carbamate) stationary phase.
    Biomedical chromatography : BMC, 2022, Volume: 36, Issue:2

    Topics: Amylose; Chromatography, High Pressure Liquid; Drug Stability; Imidazoles; Linear Models; Phenylalanine; Phenylcarbamates; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism

2022
Fully Integrated Point-of-Care Platform for the Self-Monitoring of Phenylalanine in Finger-Prick Blood.
    ACS sensors, 2023, 11-24, Volume: 8, Issue:11

    Topics: Humans; Phenylalanine; Phenylketonurias; Point-of-Care Systems; Reproducibility of Results; Sensitivity and Specificity

2023
Determination of phenylalanine enantiomers in the plasma and urine of mammals and ᴅ-amino acid oxidase deficient rodents using two-dimensional high-performance liquid chromatography.
    Biochimica et biophysica acta. Proteins and proteomics, 2021, Volume: 1869, Issue:1

    Topics: Animals; Animals, Genetically Modified; Chromatography, High Pressure Liquid; D-Amino-Acid Oxidase; Humans; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Phenylalanine; Rats; Rats, Inbred F344; Sensitivity and Specificity; Stereoisomerism; Young Adult

2021
High sensitive LC-MS/MS method for estimation of eluxadoline in human plasma and its application to pharmacokinetic study.
    Journal of pharmaceutical and biomedical analysis, 2019, Feb-20, Volume: 165

    Topics: Chromatography, Liquid; Gastrointestinal Agents; Glucuronides; Humans; Imidazoles; India; Male; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry

2019
Optical screening of hepatitis-B infected blood sera using optical technique and neural network classifier.
    Photodiagnosis and photodynamic therapy, 2019, Volume: 27

    Topics: Bilirubin; Hepatitis B; Humans; Neural Networks, Computer; Pakistan; Phenylalanine; Predictive Value of Tests; Sensitivity and Specificity; Serum Albumin; Spectrum Analysis, Raman; Tryptophan

2019
Amino acid analysis of dried blood spots for diagnosis of phenylketonuria using capillary electrophoresis-mass spectrometry equipped with a sheathless electrospray ionization interface.
    Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:25

    Topics: Amino Acids; Dried Blood Spot Testing; Electrophoresis, Capillary; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tyrosine

2013
Optimization of an HPLC method for phenylalanine and tyrosine quantization in dried blood spot.
    Clinical biochemistry, 2013, Volume: 46, Issue:18

    Topics: Adolescent; Chromatography, High Pressure Liquid; Dried Blood Spot Testing; Humans; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity; Tyrosine; Young Adult

2013
Molecularly imprinted photonic polymer based on β-cyclodextrin for amino acid sensing.
    Talanta, 2013, Nov-15, Volume: 116

    Topics: Acrylates; beta-Cyclodextrins; Crystallization; Hydrogen-Ion Concentration; Maleic Anhydrides; Molecular Imprinting; Phenylalanine; Photons; Polymerization; Polystyrenes; Sensitivity and Specificity; Stereoisomerism; Temperature

2013
(10)B-NMR determination of (10)B-BPA, (10)B-BPA-fructose complex and total (10)B in blood for BNCT.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2014, Volume: 88

    Topics: Blood Chemical Analysis; Boron; Boron Compounds; Boron Neutron Capture Therapy; Fructose; Humans; Isotopes; Magnetic Resonance Spectroscopy; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity

2014
Determination of accuracy of polycythemia vera diagnoses and use of the JAK2V617F test in the diagnostic scheme.
    Annals of hematology, 2014, Volume: 93, Issue:9

    Topics: Amino Acid Substitution; Diagnostic Errors; DNA Mutational Analysis; Genetic Testing; Humans; Janus Kinase 2; Mutation, Missense; Myeloproliferative Disorders; Phenylalanine; Polycythemia Vera; Registries; Retrospective Studies; Sensitivity and Specificity; Valine

2014
Divergent Urinary Metabolic Phenotypes between Major Depressive Disorder and Bipolar Disorder Identified by a Combined GC-MS and NMR Spectroscopic Metabonomic Approach.
    Journal of proteome research, 2015, Aug-07, Volume: 14, Issue:8

    Topics: Adult; beta-Alanine; Biomarkers; Bipolar Disorder; Depressive Disorder, Major; Diagnosis, Differential; Female; Formates; Gas Chromatography-Mass Spectrometry; Humans; Hydroxybutyrates; Magnetic Resonance Spectroscopy; Male; Metabolome; Metabolomics; Phenylalanine; Propionates; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Young Adult

2015
Founder effect is responsible for the p.Leu131Phe heparin-binding-site antithrombin mutation common in Hungary: phenotype analysis in a large cohort.
    Journal of thrombosis and haemostasis : JTH, 2016, Volume: 14, Issue:4

    Topics: Adolescent; Adult; Aged; Antithrombins; Arteries; Binding Sites; Child; Child, Preschool; Cohort Studies; Factor Xa; Female; Founder Effect; Genetic Association Studies; Heparin; Heterozygote; Humans; Hungary; Leucine; Microsatellite Repeats; Middle Aged; Mutation; Phenotype; Phenylalanine; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications, Cardiovascular; Sensitivity and Specificity; Thrombosis; Young Adult

2016
    Journal of developmental and life-course criminology, 2016, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Amino Acid Substitution; Anemia, Aplastic; Athletes; Athletic Performance; Bone Marrow Transplantation; Carcinoma, Non-Small-Cell Lung; Catalytic Domain; Cell Count; Child; Child, Preschool; Escherichia coli; Female; Gene Expression; Graft Survival; Graft vs Host Disease; Histocompatibility Testing; Humans; Hydrogen Bonding; Immunosuppression Therapy; Inosine Monophosphate; Integrin alphaVbeta3; Kinetics; Knee Joint; Lung Neoplasms; Lymphatic Metastasis; Male; Mediastinal Neoplasms; Middle Aged; Molecular Dynamics Simulation; Muscle, Skeletal; Mutation; Organotechnetium Compounds; Pentosyltransferases; Peptides, Cyclic; Phenylalanine; Plasmodium falciparum; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protozoan Proteins; Radiopharmaceuticals; Recombinant Proteins; Running; Sensitivity and Specificity; Serine; Siblings; Single Photon Emission Computed Tomography Computed Tomography; Soccer; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Threonine; Time Factors; Torque; Treatment Outcome; Tryptophan; Tyrosine; Young Adult

2016
Copper nanocluster-enhanced luminol chemiluminescence for high-selectivity sensing of tryptophan and phenylalanine.
    Luminescence : the journal of biological and chemical luminescence, 2017, Volume: 32, Issue:6

    Topics: Copper; Humans; Luminescence; Luminescent Measurements; Luminol; Phenylalanine; Sensitivity and Specificity; Tryptophan

2017
Hollow spherical nanostructured polydiphenylamine for direct electrochemistry and glucose biosensor.
    Biosensors & bioelectronics, 2009, Mar-15, Volume: 24, Issue:7

    Topics: Biosensing Techniques; Dipeptides; Electrochemistry; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Glucose; Glucose Oxidase; Microelectrodes; Nanostructures; Nanotechnology; Phenylalanine; Polymers; Porosity; Reproducibility of Results; Sensitivity and Specificity

2009
Cuban neonatal screening of phenylketonuria using an ultramicro-fluorometric test.
    Clinica chimica acta; international journal of clinical chemistry, 2009, Volume: 402, Issue:1-2

    Topics: Blood Specimen Collection; Cuba; Fluorometry; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Sensitivity and Specificity

2009
Chiral recognition of mandelic acid by L-phenylalanine-modified sensor using quartz crystal microbalance.
    Biosensors & bioelectronics, 2009, May-15, Volume: 24, Issue:9

    Topics: Biosensing Techniques; Electrochemistry; Isomerism; Mandelic Acids; Microtechnology; Phenylalanine; Quartz; Sensitivity and Specificity; Surface Properties

2009
Reproducibility of cerebral phenylalanine levels in patients with phenylketonuria determined by 1H-MR spectroscopy.
    Magnetic resonance in medicine, 2009, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Biomarkers; Brain; Child; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phenylalanine; Phenylketonurias; Protons; Reproducibility of Results; Sensitivity and Specificity; Young Adult

2009
Chiral recognition of mandelic acid on quartz crystal microbalance by vapor diffused molecular assembly method.
    Journal of nanoscience and nanotechnology, 2009, Volume: 9, Issue:5

    Topics: Biosensing Techniques; Gold; Isomerism; Mandelic Acids; Phenylalanine; Quartz; Sensitivity and Specificity; Surface Properties

2009
A simple and rapid method for measurement of (10)B-para-boronophenylalanine in the blood for boron neutron capture therapy using fluorescence spectrophotometry.
    Journal of radiation research, 2009, Volume: 50, Issue:4

    Topics: Animals; Biological Assay; Blood Chemical Analysis; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Humans; Mice; Mice, Inbred C3H; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Sulfhydryl Compounds

2009
Determination of phenylalanine in blood by high-performance anion-exchange chromatography-pulsed amperometric detection to diagnose phenylketonuria.
    Journal of chromatography. A, 2009, Jul-24, Volume: 1216, Issue:30

    Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Sensitivity and Specificity

2009
A microsystem of low-voltage-driven electrophoresis on microchip with array electrode pairs for the separation of amino acids.
    Analytical and bioanalytical chemistry, 2009, Volume: 394, Issue:7

    Topics: Dimethylpolysiloxanes; Electrochemistry; Electrodes; Electrophoresis, Capillary; Lysine; Microfluidics; Phenylalanine; Sensitivity and Specificity; Silicon; Temperature; Time Factors

2009
Heart-cutting 2D-CE with on-line preconcentration for the chiral analysis of native amino acids.
    Electrophoresis, 2010, Volume: 31, Issue:6

    Topics: Amino Acids; Crown Ethers; Electrophoresis, Capillary; Formates; Phenylalanine; Sensitivity and Specificity; Stereoisomerism; Threonine

2010
Immobilization of phenylalanine dehydrogenase and its application in flow-injection analysis system for determination of plasma phenylalanine.
    Applied biochemistry and biotechnology, 2011, Volume: 163, Issue:2

    Topics: Amino Acid Oxidoreductases; Bioreactors; DEAE-Cellulose; Diamines; Enzymes, Immobilized; Flow Injection Analysis; Glutaral; Humans; Hydrogen-Ion Concentration; Kinetics; NAD; Phenylalanine; Phenylketonurias; Sensitivity and Specificity; Sporosarcina; Temperature

2011
Prospective study of p-[123I]iodo-L-phenylalanine and SPECT for the evaluation of newly diagnosed cerebral lesions: specific confirmation of glioma.
    European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:12

    Topics: Brain Neoplasms; Female; Glioma; Humans; Male; Middle Aged; Phenylalanine; Prospective Studies; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon

2010
Determination of unconjugated aromatic acids in urine by capillary electrophoresis with dual electrochemical detection--potential application in fast diagnosis of phenylketonuria.
    Electrophoresis, 2010, Volume: 31, Issue:17

    Topics: Adult; Biomarkers; Electrodes; Electrophoresis, Capillary; Female; Humans; Hydrogen-Ion Concentration; Infant; Linear Models; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Reproducibility of Results; Sensitivity and Specificity; Sodium Dodecyl Sulfate

2010
99mTc-tetrofosmin SPECT for the evaluation of cerebral lesions.
    European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:12

    Topics: Brain Neoplasms; Humans; Organophosphorus Compounds; Organotechnetium Compounds; Phenylalanine; Prospective Studies; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon

2010
Antibody-based multiplex analysis of structurally closely related chiral molecules.
    The Analyst, 2011, Mar-21, Volume: 136, Issue:6

    Topics: Fluorescent Antibody Technique; Lactic Acid; Microarray Analysis; Phenylalanine; Sensitivity and Specificity; Stereoisomerism

2011
Chromatographic diagnosis of maple syrup urine disease by measuring the L-alloisoleucine/L-phenylalanine ratio in dried blood spots.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Jul-15, Volume: 879, Issue:22

    Topics: Adult; Blood Specimen Collection; Chromatography, High Pressure Liquid; Humans; Infant, Newborn; Isoleucine; Male; Maple Syrup Urine Disease; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity

2011
Log-scale dose response of inhibitors on a chip.
    Analytical chemistry, 2011, Aug-15, Volume: 83, Issue:16

    Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Inhibitory Concentration 50; Kinetics; Lab-On-A-Chip Devices; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Microchip Analytical Procedures; Neoplasms; Phenylalanine; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiophenes

2011
Alternately binding probe competitive PCR as a simple, cost-effective, and accurate quantification method for JAK2V617F allele burden in myeloproliferative neoplasms.
    Leukemia research, 2011, Volume: 35, Issue:12

    Topics: Alleles; Amino Acid Substitution; Binding, Competitive; Bone Marrow Neoplasms; Cell Line, Tumor; Cost-Benefit Analysis; DNA Mutational Analysis; DNA Probes; Gene Dosage; Humans; Janus Kinase 2; Models, Biological; Myeloproliferative Disorders; Phenylalanine; Polymerase Chain Reaction; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Valine

2011
Spectrofluorimetric determination of phenylalanine based on fluorescence enhancement of europium ion immobilized with sol-gel method.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2011, Volume: 83, Issue:1

    Topics: Equipment Design; Europium; Filtration; Humans; Hydrogen-Ion Concentration; Phase Transition; Phenylalanine; Sensitivity and Specificity; Spectrometry, Fluorescence

2011
Liver function assessment with three (13)C breath tests by two-point measurements.
    Isotopes in environmental and health studies, 2012, Volume: 48, Issue:4

    Topics: Acetamides; Aged; Breath Tests; Carbon Dioxide; Carbon Isotopes; Female; Hepatitis, Chronic; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methionine; Middle Aged; Phenylalanine; Sensitivity and Specificity

2012
50 years ago in the Journal of Pediatrics: comparison of serum phenylalanine levels with growth in Guthrie's inhibition assay in newborn infants.
    The Journal of pediatrics, 2012, Volume: 161, Issue:3

    Topics: History, 20th Century; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Sensitivity and Specificity; Tandem Mass Spectrometry

2012
Transition metal cation separations with a resorcinarene-based amino acid stationary phase.
    The Analyst, 2013, Mar-07, Volume: 138, Issue:5

    Topics: Alanine; Amino Acids; Calixarenes; Carboxylic Acids; Cations, Divalent; Chelating Agents; Chromatography, Ion Exchange; Macrocyclic Compounds; Metals; Phenylalanine; Sensitivity and Specificity; Transition Elements

2013
Development of an UPLC mass spectrometry method for measurement of myofibrillar protein synthesis: application to analysis of murine muscles during cancer cachexia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, Mar-15, Volume: 114, Issue:6

    Topics: Adenomatous Polyposis Coli; Animals; Biomarkers; Biopsy; Cachexia; Chromatography, Liquid; Diaphragm; Down-Regulation; Genes, APC; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle Proteins; Muscle, Skeletal; Myofibrils; Phenylalanine; Proteomics; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors

2013
Validation of the phenylalanine/tyrosine ratio determined by tandem mass spectrometry: sensitive newborn screening for phenylketonuria.
    Clinical chemistry and laboratory medicine, 2002, Volume: 40, Issue:7

    Topics: Blood Specimen Collection; Chromatography, Ion Exchange; Fluorometry; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tyrosine

2002
Process control for enhanced L-phenylalanine production using different recombinant Escherichia coli strains.
    Biotechnology and bioengineering, 2002, Dec-30, Volume: 80, Issue:7

    Topics: Bioreactors; Cells, Cultured; Escherichia coli; Feedback; Glucose; Homeostasis; Phenylalanine; Pilot Projects; Quality Control; Recombinant Proteins; Recombination, Genetic; Reproducibility of Results; Sensitivity and Specificity; Species Specificity; Tyrosine

2002
Evaluation of vascular endothelial growth factor blockade and matrix metalloproteinase inhibition as a combination therapy for experimental human pancreatic cancer.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2003, Volume: 7, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Chi-Square Distribution; Disease Models, Animal; Drug Therapy, Combination; Endothelial Growth Factors; Humans; Intercellular Signaling Peptides and Proteins; Lymphokines; Male; Matrix Metalloproteinases; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Pancreatic Neoplasms; Phenylalanine; Probability; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric; Thiophenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
Simultaneous measurement of phenylalanine and tyrosine in phenylketonuric plasma and dried blood by high-performance liquid chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, May-05, Volume: 788, Issue:1

    Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Female; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tyrosine

2003
Free amino acid pool and muscle protein balance after resistance exercise.
    Medicine and science in sports and exercise, 2003, Volume: 35, Issue:5

    Topics: Adult; Amino Acids, Essential; Biological Transport; Case-Control Studies; Exercise; Humans; Leg; Male; Multivariate Analysis; Muscle Proteins; Muscle, Skeletal; Oxygen Consumption; Phenylalanine; Physical Exertion; Probability; Reference Values; Regional Blood Flow; Sensitivity and Specificity; Weight Lifting

2003
Model to assess muscle protein turnover: domain of validity using amino acyl-tRNA vs. surrogate measures of precursor pool.
    American journal of physiology. Endocrinology and metabolism, 2003, Volume: 285, Issue:5

    Topics: Adult; Arteries; Biological Transport; Carbon Isotopes; False Negative Reactions; False Positive Reactions; Humans; Keto Acids; Kinetics; Leucine; Mathematics; Models, Biological; Muscle Proteins; Muscle, Skeletal; Nitrogen Isotopes; Phenylalanine; RNA, Transfer, Amino Acyl; Sensitivity and Specificity; Veins

2003
Simultaneous determination of tyrosine, phenylalanine and deoxyguanosine oxidation products by liquid chromatography-tandem mass spectrometry as non-invasive biomarkers for oxidative damage.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Jan-25, Volume: 799, Issue:2

    Topics: Calibration; Chromatography, Gas; Chromatography, High Pressure Liquid; Deoxyguanosine; Humans; Mass Spectrometry; Oxidative Stress; Phenylalanine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tyrosine

2004
p-[123I]iodo-L-phenylalanine for detection of pancreatic cancer: basic investigations of the uptake characteristics in primary human pancreatic tumour cells and evaluation in in vivo models of human pancreatic adenocarcinoma.
    European journal of nuclear medicine and molecular imaging, 2004, Volume: 31, Issue:4

    Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Drug Evaluation, Preclinical; Humans; Metabolic Clearance Rate; Mice; Mice, SCID; Organ Specificity; Pancreatic Neoplasms; Phenylalanine; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution

2004
Pharmacologic preconditioning of JTE-607, a novel cytokine inhibitor, attenuates ischemia-reperfusion injury in the myocardium.
    The Journal of thoracic and cardiovascular surgery, 2004, Volume: 127, Issue:6

    Topics: Animals; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Phenylalanine; Piperazines; Probability; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Survival Rate

2004
L-amino acids regulate parathyroid hormone secretion.
    The Journal of biological chemistry, 2004, Sep-10, Volume: 279, Issue:37

    Topics: Amino Acids; Calcium; Cytoplasm; Dose-Response Relationship, Drug; Humans; Ions; Magnesium; Parathyroid Glands; Parathyroid Hormone; Phenylalanine; Receptors, Calcium-Sensing; Sensitivity and Specificity; Spermine; Time Factors; Tryptophan

2004
Determination of nateglinide in animal plasma by micellar electrokinetic chromatography and on-line sweeping technique.
    Journal of pharmaceutical and biomedical analysis, 2004, Sep-21, Volume: 36, Issue:1

    Topics: Animals; Buffers; Chromatography, Micellar Electrokinetic Capillary; Cyclohexanes; Hydrogen-Ion Concentration; Nateglinide; Phenylalanine; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling

2004
Study on the bioavailability of nateglinide-hydroxypropyl-beta-cyclodextrin complex capsule in rabbits by liquid chromatographic-tandem mass spectrometry.
    Biomedical chromatography : BMC, 2004, Volume: 18, Issue:8

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Biological Availability; Capsules; Chemistry, Pharmaceutical; Chromatography, Liquid; Cyclohexanes; Male; Mass Spectrometry; Nateglinide; Phenylalanine; Quality Control; Rabbits; Sensitivity and Specificity

2004
Phenylalanine hydroxylase deficiency in the peripheral lymphocytes from phenylketonuria.
    The Journal of dermatology, 1977, Volume: 4, Issue:2

    Topics: Autoradiography; Case-Control Studies; Cells, Cultured; Female; Humans; Japan; Lymphocytes; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Reference Values; Sampling Studies; Sensitivity and Specificity; Tyrosine

1977
Applying metabolic profiling techniques for stimulus-response experiments: chances and pitfalls.
    Advances in biochemical engineering/biotechnology, 2005, Volume: 92

    Topics: Algorithms; Bioreactors; Escherichia coli; Escherichia coli Proteins; Flow Injection Analysis; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Models, Biological; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity; Signal Transduction; Stochastic Processes

2005
Validity of 13C-phenylalanine breath test to evaluate functional capacity of hepatocyte in patients with liver cirrhosis and acute hepatitis.
    Alimentary pharmacology & therapeutics, 2005, Apr-01, Volume: 21, Issue:7

    Topics: Acute Disease; Breath Tests; Female; Hepatitis; Hepatocytes; Humans; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Phenylalanine; Sensitivity and Specificity

2005
A double mutation in the extracellular Ca2+-sensing receptor's venus flytrap domain that selectively disables L-amino acid sensing.
    The Journal of biological chemistry, 2005, Aug-12, Volume: 280, Issue:32

    Topics: Allosteric Site; Amino Acids; Aminoacylation; Blotting, Western; Calcium; Cell Line; Cytoplasm; DNA Mutational Analysis; Humans; Kinetics; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Receptors, Calcium-Sensing; Sensitivity and Specificity; Time Factors; Transfection

2005
Compact detector for proteins based on two-photon excitation of native fluorescence.
    Analytical chemistry, 2005, Jun-01, Volume: 77, Issue:11

    Topics: Animals; Cattle; Equipment Design; Equipment Failure Analysis; Fluorescence; Lab-On-A-Chip Devices; Lasers; Microchip Analytical Procedures; Optics and Photonics; Phenylalanine; Photons; Sensitivity and Specificity; Serum Albumin, Bovine; Time Factors; Tryptophan; Tyrosine

2005
Development of microwave-assisted derivatization followed by gas chromatography/mass spectrometry for fast determination of amino acids in neonatal blood samples.
    Rapid communications in mass spectrometry : RCM, 2005, Volume: 19, Issue:16

    Topics: Amino Acids; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Microwaves; Phenylalanine; Phenylketonurias; Sensitivity and Specificity; Time Factors; Tyrosine

2005
[Tetrahydrobiopterin loading test in differential diagnosis among hyperphenylalaninemia patients].
    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2005, Volume: 22, Issue:4

    Topics: Biopterins; Diagnosis, Differential; Dihydropteridine Reductase; Female; Humans; Infant; Infant, Newborn; Male; Mass Screening; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Sensitivity and Specificity

2005
Neighbouring group processes in the deamination of protonated phenylalanine derivatives.
    Organic & biomolecular chemistry, 2005, Oct-21, Volume: 3, Issue:20

    Topics: Ammonia; Carbon Monoxide; Deamination; Models, Chemical; Molecular Structure; Phenylalanine; Protons; Sensitivity and Specificity; Stereoisomerism; Tandem Mass Spectrometry; Water

2005
Extended tetrahydrobiopterin loading test in the diagnosis of cofactor-responsive phenylketonuria: a pilot study.
    Molecular genetics and metabolism, 2005, Volume: 86 Suppl 1

    Topics: Biopterins; Humans; Male; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Sensitivity and Specificity

2005
Capillary electrophoresis-electrospray mass spectrometry and HR-ICP-MS for the detection and quantification of 10B-boronophenylalanine (10B-BPA) used in boron neutron capture therapy.
    Analytical and bioanalytical chemistry, 2006, Volume: 384, Issue:3

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Electrophoresis, Capillary; Endothelial Cells; Glioma; Humans; Isotopes; Mass Spectrometry; Molecular Structure; Phenylalanine; Rats; Sensitivity and Specificity; Time Factors

2006
A quantitative bacterial micro-assay for rapid detection of serum phenylalanine in dry blood-spots: application in phenylketonuria screening.
    Journal of applied genetics, 2006, Volume: 47, Issue:1

    Topics: Amino Acid Oxidoreductases; Blood Chemical Analysis; Chromatography, High Pressure Liquid; False Positive Reactions; Glutamates; Humans; Mass Screening; Phenylalanine; Phenylketonurias; Sensitivity and Specificity

2006
Predicting the phenylalanine blood concentration from urine analyses. An approach to noninvasive monitoring of patients with phenylketonuria.
    Journal of inherited metabolic disease, 2005, Volume: 28, Issue:6

    Topics: Adult; Analysis of Variance; Blood Chemical Analysis; Clinical Laboratory Techniques; Creatinine; Diet; Electroencephalography; Female; Humans; Male; Middle Aged; Models, Statistical; Mutation; Phenylalanine; Phenylketonurias; Regression Analysis; Sensitivity and Specificity; Time Factors

2005
Comparative biodistribution study of the new tumor tracer [123I]-2-iodo-L-phenylalanine with [123I]-2-iodo-L-tyrosine.
    Nuclear medicine and biology, 2006, Volume: 33, Issue:1

    Topics: Animals; Cell Line, Tumor; Female; Iodine Radioisotopes; Metabolic Clearance Rate; Mice; Monoiodotyrosine; Organ Specificity; Phenylalanine; Radiopharmaceuticals; Reproducibility of Results; Rhabdomyosarcoma; Sensitivity and Specificity; Tissue Distribution; Tomography, Emission-Computed, Single-Photon

2006
Influence of sedation and data acquisition method on tracer uptake in animal models: [123I]-2-iodo-L-phenylalanine in pentobarbital-sedated tumor-bearing athymic mice.
    Nuclear medicine and biology, 2006, Volume: 33, Issue:1

    Topics: Animals; Artifacts; Cell Line, Tumor; Disease Models, Animal; Hypnotics and Sedatives; Image Interpretation, Computer-Assisted; Iodine Radioisotopes; Male; Metabolic Clearance Rate; Mice; Mice, Nude; Organ Specificity; Pentobarbital; Phenylalanine; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Rhabdomyosarcoma; Sensitivity and Specificity; Tissue Distribution

2006
VUV photoelectron imaging of biological nanoparticles: ionization energy determination of nanophase glycine and phenylalanine-glycine-glycine.
    Physical chemistry chemical physics : PCCP, 2006, Apr-28, Volume: 8, Issue:16

    Topics: Glycine; Ions; Kinetics; Models, Biological; Nanostructures; Nanotechnology; Particle Size; Phenylalanine; Photochemistry; Photons; Sensitivity and Specificity; Spectrum Analysis; X-Ray Diffraction

2006
Occurrence of the leucine-to-phenylalanine knockdown resistance (kdr) mutation in Anopheles arabiensis populations in Tanzania, detected by a simplified high-throughput SSOP-ELISA method.
    Malaria journal, 2006, Jul-05, Volume: 5

    Topics: Animals; Anopheles; Enzyme-Linked Immunosorbent Assay; Female; Insecticide Resistance; Leucine; Mutation; Oligonucleotide Probes; Phenylalanine; Polymerase Chain Reaction; Pyrethrins; Sensitivity and Specificity; Tanzania

2006
Role of the middle residue in the triple tryptophan electron transfer chain of DNA photolyase: ultrafast spectroscopy of a Trp-->Phe mutant.
    The journal of physical chemistry. B, 2006, Aug-17, Volume: 110, Issue:32

    Topics: Deoxyribodipyrimidine Photo-Lyase; Electron Transport; Escherichia coli; Flavin-Adenine Dinucleotide; Free Radicals; Mutation; Phenylalanine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tryptophan

2006
Dehydrogenase based reagentless biosensor for monitoring phenylketonuria.
    Biosensors & bioelectronics, 2007, May-15, Volume: 22, Issue:11

    Topics: Amino Acid Oxidoreductases; Biosensing Techniques; Electrochemistry; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Humans; Indicators and Reagents; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity; Urinalysis

2007
Application of an enzyme chip to the microquantification of l-phenylalanine.
    Analytical biochemistry, 2006, Dec-01, Volume: 359, Issue:1

    Topics: Amino Acid Oxidoreductases; Blood Stains; Histidine; Humans; Infant, Newborn; Microchemistry; Neonatal Screening; Phenylalanine; Phenylketonurias; Protein Array Analysis; Reproducibility of Results; Sensitivity and Specificity

2006
FRET analysis of protein conformational change through position-specific incorporation of fluorescent amino acids.
    Nature methods, 2006, Volume: 3, Issue:11

    Topics: Calmodulin; Cell-Free System; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Phenylalanine; Protein Conformation; Sensitivity and Specificity; Spectrometry, Fluorescence; Structure-Activity Relationship

2006
Assembly of hybrid synthetic capsules.
    Angewandte Chemie (International ed. in English), 2007, Volume: 46, Issue:1-2

    Topics: Calixarenes; Chloroform; Dimerization; Heterocyclic Compounds, 4 or More Rings; Hydrogen Bonding; Macrocyclic Compounds; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Phenylalanine; Reference Standards; Sensitivity and Specificity; Stereoisomerism

2007
Supramolecular-mediated immobilization of L-phenylalanine dehydrogenase on cyclodextrin-coated Au electrodes for biosensor applications.
    Biotechnology letters, 2007, Volume: 29, Issue:3

    Topics: Amino Acid Oxidoreductases; Bacillus; beta-Cyclodextrins; Biosensing Techniques; Coated Materials, Biocompatible; Electrochemistry; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Gold; Microelectrodes; Multiprotein Complexes; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity

2007
Quantitative determination of JAK2 V617F by TaqMan: An absolute measure of averaged copies per cell that may be associated with the different types of myeloproliferative disorders.
    The Journal of molecular diagnostics : JMD, 2007, Volume: 9, Issue:2

    Topics: Amino Acid Substitution; Case-Control Studies; Gene Dosage; Humans; Janus Kinase 2; Myeloproliferative Disorders; Phenotype; Phenylalanine; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Valine

2007
Amplification refractory mutation system, a highly sensitive and simple polymerase chain reaction assay, for the detection of JAK2 V617F mutation in chronic myeloproliferative disorders.
    The Journal of molecular diagnostics : JMD, 2007, Volume: 9, Issue:2

    Topics: Chronic Disease; DNA Mutational Analysis; Exons; Genetic Testing; Genome, Human; Humans; Janus Kinase 2; Mutation; Myeloproliferative Disorders; Phenylalanine; Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity; Valine

2007
Nateglinide quantification in rabbit plasma by HPLC: optimization and application to pharmacokinetic study.
    Journal of pharmaceutical and biomedical analysis, 2007, May-09, Volume: 44, Issue:1

    Topics: Administration, Oral; Animals; Area Under Curve; Buffers; Calibration; Chromatography, High Pressure Liquid; Cold Temperature; Cyclohexanes; Drug Stability; Freezing; Half-Life; Hydrogen-Ion Concentration; Hypoglycemic Agents; Metabolic Clearance Rate; Molecular Structure; Nateglinide; Phenylalanine; Rabbits; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Time Factors

2007
Population quantile-quantile plots for monitoring assay performance in newborn screening.
    Journal of inherited metabolic disease, 2007, Volume: 30, Issue:4

    Topics: Calibration; Carnitine; DNA Mutational Analysis; Humans; Infant, Newborn; Mass Screening; Mass Spectrometry; Mutation; Neonatal Screening; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity; United Kingdom

2007
Intra-individual comparison of the human biodistribution and dosimetry of the D and L isomers of 2-[123I]iodo-phenylalanine.
    Nuclear medicine communications, 2007, Volume: 28, Issue:10

    Topics: Adult; Humans; Isomerism; Male; Metabolic Clearance Rate; Organ Specificity; Phenylalanine; Radiopharmaceuticals; Sensitivity and Specificity; Structure-Activity Relationship; Tissue Distribution; Whole-Body Counting

2007
Surface recognition and fluorescence sensing of histone by dansyl-appended cyclophane-based resorcinarene trimer.
    Journal of the American Chemical Society, 2007, Nov-07, Volume: 129, Issue:44

    Topics: Aza Compounds; Calixarenes; Dimerization; Ethers, Cyclic; Fluorescence; Histones; Macrocyclic Compounds; Models, Chemical; Molecular Conformation; Phenylalanine; Sensitivity and Specificity; Surface Properties; Time Factors

2007
Characterization of white matter alterations in phenylketonuria by magnetic resonance relaxometry and diffusion tensor imaging.
    Magnetic resonance in medicine, 2007, Volume: 58, Issue:6

    Topics: Adult; Brain; Diffusion Magnetic Resonance Imaging; Female; Humans; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity

2007
PCR assay for differentiating between Group I (proteolytic) and Group II (nonproteolytic) strains of Clostridium botulinum.
    International journal of food microbiology, 2008, May-10, Volume: 124, Issue:1

    Topics: Botulism; Clostridium botulinum; Food Contamination; Food Microbiology; Humans; Phenylalanine; Phylogeny; Polymerase Chain Reaction; Sensitivity and Specificity; Species Specificity

2008
Enzymatic-chemical preparation of quinoxaline derivatives from L-amino acids for gas chromatographic-mass spectrometric analyses.
    Analytical biochemistry, 1995, Aug-10, Volume: 229, Issue:2

    Topics: Amino Acid Oxidoreductases; Amino Acids; Carbon Isotopes; Chromatography, Ion Exchange; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Isotope Labeling; Phenylalanine; Quinoxalines; Sensitivity and Specificity

1995
Synthesis and characterization of a bioluminogenic substrate for alpha-chymotrypsin.
    Analytical biochemistry, 1994, Volume: 221, Issue:2

    Topics: Chromatography, High Pressure Liquid; Chymotrypsin; Firefly Luciferin; Indicators and Reagents; Kinetics; Luminescent Measurements; Magnetic Resonance Spectroscopy; Phenylalanine; Sensitivity and Specificity; Substrate Specificity

1994
Rapid diagnosis of maple syrup urine disease in blood spots from newborns by tandem mass spectrometry.
    Clinical chemistry, 1995, Volume: 41, Issue:1

    Topics: False Positive Reactions; Humans; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Mass Spectrometry; Neonatal Screening; Paper; Phenylalanine; Reference Values; Sensitivity and Specificity; Valine

1995
Phenylketonuria screening with a fluorometric microplate assay.
    European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 1994, Volume: 32, Issue:7

    Topics: Fluorometry; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity

1994
Neonatal screening for phenylketonuria: evaluation of an automated enzymatic method.
    Annals of clinical biochemistry, 1994, Volume: 31 ( Pt 2)

    Topics: Amino Acid Oxidoreductases; Autoanalysis; Chromatography, High Pressure Liquid; Cost-Benefit Analysis; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Pilot Projects; Reproducibility of Results; Sensitivity and Specificity

1994
Multicomponent analysis for alkaline phosphatase isoenzyme determination by multiple linear regression.
    Clinical chemistry, 1994, Volume: 40, Issue:5

    Topics: Alkaline Phosphatase; Bone and Bones; Electrophoresis; Hot Temperature; Humans; Intestines; Isoenzymes; Levamisole; Liver; Phenylalanine; Placenta; Regression Analysis; Sensitivity and Specificity

1994
Assay of the human liver citric acid cycle probe phenylacetylglutamine and of phenylacetate in plasma by gas chromatography-mass spectrometry.
    Analytical biochemistry, 1993, Volume: 212, Issue:1

    Topics: Adult; Citric Acid Cycle; Evaluation Studies as Topic; Gas Chromatography-Mass Spectrometry; Glutamine; Humans; Liver; Molecular Probes; Phenylacetates; Phenylalanine; Sensitivity and Specificity

1993
Tissue-nonspecific alkaline phosphatase participates in the establishment and growth of feather germs in embryonic chick skin cultures.
    Developmental dynamics : an official publication of the American Association of Anatomists, 1995, Volume: 204, Issue:1

    Topics: Alkaline Phosphatase; Amino Acid Sequence; Animals; Base Sequence; Chick Embryo; Cloning, Molecular; DNA; Feathers; Homoarginine; Levamisole; Molecular Sequence Data; Organ Culture Techniques; Phenylalanine; RNA, Messenger; Sensitivity and Specificity; Sequence Homology, Amino Acid; Skin; Tetramisole

1995
An automated enzymatic method on the Roche COBAS MIRA S for monitoring phenylalanine in dried blood spots of patients with phenylketonuria.
    Clinical biochemistry, 1996, Volume: 29, Issue:2

    Topics: Amino Acid Oxidoreductases; Blood Chemical Analysis; Evaluation Studies as Topic; Humans; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity

1996
Determination of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine in human plasma by solid-phase extraction and column-switching high-performance liquid chromatography with ultraviolet detection.
    Journal of chromatography. B, Biomedical applications, 1996, Apr-12, Volume: 678, Issue:2

    Topics: Chromatography, High Pressure Liquid; Cyclohexanes; Humans; Hypoglycemic Agents; Nateglinide; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity

1996
Quantitation of L-amino acids by substrate recycling between an aminotransferase and a dehydrogenase: application to the determination of L-phenylalanine in human blood.
    Analytical biochemistry, 1996, Feb-01, Volume: 234, Issue:1

    Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Bacillus; Cytosol; Humans; Indicators and Reagents; Kidney; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry; Transaminases

1996
Trace analysis in chiral separation of selected amino enantiomers.
    Journal of pharmaceutical and biomedical analysis, 1996, Volume: 14, Issue:8-10

    Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Fluorometry; Leucine; Perchlorates; Phenylalanine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism; Threonine

1996
Time-resolved fluorescence. An approach in protein analysis.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Animals; Cattle; Humans; Models, Theoretical; Phenylalanine; Proteins; Sensitivity and Specificity; Serum Albumin; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors; Tryptophan; Tyrosine

1996
Successful and unsuccessful approaches to imaging carcinoids: comparison of a radiolabelled tryptophan hydroxylase inhibitor with a tracer of biogenic amine uptake and storage, and a somatostatin analogue.
    European journal of nuclear medicine, 1996, Volume: 23, Issue:2

    Topics: 3-Iodobenzylguanidine; Adult; Animals; Carcinoid Tumor; Dogs; Enzyme Inhibitors; Female; Humans; Indium Radioisotopes; Iodine Radioisotopes; Iodobenzenes; Mast-Cell Sarcoma; Mice; Middle Aged; Neoplasms, Experimental; Phenylalanine; Predictive Value of Tests; Radionuclide Imaging; Rats; Sensitivity and Specificity; Serotonin; Somatostatin; Tissue Distribution; Tryptophan Hydroxylase

1996
Design of specific structures using alpha,beta-dehydro-phenylalanine residues: synthesis, crystal structure, and molecular conformation of Boc-L-Val-delta Phe-delta Phe-L-Val-delta Phe-delta Phe-L-Val-OCH3, a 3(10)-helical heptapeptide.
    Biopolymers, 1997, Volume: 41, Issue:1

    Topics: Crystallography, X-Ray; Hydrogen Bonding; Oligopeptides; Phenylalanine; Protein Conformation; Sensitivity and Specificity

1997
A tryptophan-2-monooxygenase based amperometric biosensor for L-tryptophan determination: use of a competitive inhibitor as a tool for selectivity increase.
    Biosensors & bioelectronics, 1997, Volume: 12, Issue:5

    Topics: Biosensing Techniques; Mixed Function Oxygenases; Phenylalanine; Sensitivity and Specificity; Tryptophan

1997
Microtiter plate assay for biopterin using cryopreserved Crithidia fasciculata.
    Methods in enzymology, 1997, Volume: 281

    Topics: Animals; Biological Assay; Biopterins; Crithidia fasciculata; Cryoprotective Agents; Humans; Molecular Structure; Phenylalanine; Phenylketonurias; Reference Values; Reproducibility of Results; Sensitivity and Specificity

1997
Quantitation of 4-cyclohexyl-2-hydroxy-3-(3-methylsulfanyl-2- [2-[(morpholine-4-carbonyl)amino]-3-phenylpropionylamino]propi onylamino ) butyric acid isopropyl ester (CP-80,794), a renin inhibitor, and its hydrolytic cleavage metabolite 2-[(morpholine-4-c
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Aug-29, Volume: 696, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Dipeptides; Dogs; Humans; Morpholines; Phenylalanine; Reference Standards; Renin; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence

1997
Rhodopsins from three frog and toad species: sequences and functional comparisons.
    Experimental eye research, 1998, Volume: 66, Issue:3

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Bufo bufo; Bufo marinus; DNA; Hot Temperature; Molecular Sequence Data; Phenylalanine; Polymerase Chain Reaction; Rana temporaria; Ranidae; Rhodopsin; RNA, Messenger; Sensitivity and Specificity; Sequence Analysis, DNA; Sequence Analysis, RNA; Species Specificity; Spectrum Analysis

1998
Quantitative analytical methods for the determination of a new hypertension drug, CGS 25462, and its metabolites (CGS 25659 and CGS 24592) in human plasma by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Mar-20, Volume: 706, Issue:2

    Topics: Administration, Oral; Antihypertensive Agents; Biphenyl Compounds; Chromatography, High Pressure Liquid; Circadian Rhythm; Half-Life; Humans; Male; Organophosphonates; Phenylalanine; Prodrugs; Protease Inhibitors; Reproducibility of Results; Sensitivity and Specificity; Temperature; Time Factors

1998
Accurate measurement of cholecystokinin in plasma.
    Clinical chemistry, 1998, Volume: 44, Issue:5

    Topics: Adult; Animals; Antibodies; Antibody Specificity; Cholecystokinin; Cross Reactions; Female; Gastrins; Guinea Pigs; Humans; Immunization; Intestinal Mucosa; Male; Mice; Peptide Fragments; Phenylalanine; Rabbits; Radioimmunoassay; Reproducibility of Results; Sensitivity and Specificity; Swine; Tyrosine

1998
Assessment of the reliability of single blastomere analysis for preimplantation diagnosis of the delta F508 deletion causing cystic fibrosis in clinical practice.
    Prenatal diagnosis, 1998, Volume: 18, Issue:13

    Topics: Biopsy; Blastomeres; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Embryonic Development; Female; Gene Deletion; Genotype; Heterozygote; Humans; Phenylalanine; Polymerase Chain Reaction; Pregnancy; Prenatal Diagnosis; Sensitivity and Specificity

1998
Sensitivity of electrospray-tandem mass spectrometry using the phenylalanine/tyrosine-ratio for differential diagnosis of hyperphenylalaninemia in neonates.
    Clinica chimica acta; international journal of clinical chemistry, 1999, Volume: 283, Issue:1-2

    Topics: Diagnosis, Differential; Humans; Infant, Newborn; Mass Spectrometry; Phenylalanine; Phenylketonurias; Predictive Value of Tests; Reference Values; Sensitivity and Specificity; Tyrosine

1999
Repair of potentially lethal damage by total and quiescent cells in solid tumors following a neutron capture reaction.
    Journal of cancer research and clinical oncology, 1999, Volume: 125, Issue:11

    Topics: Animals; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Division; Cytochalasin B; DNA Damage; Dose-Response Relationship, Radiation; Female; Gamma Rays; Mice; Mice, Inbred C3H; Micronucleus Tests; Neoplasm Transplantation; Phenylalanine; Sensitivity and Specificity; Sulfhydryl Compounds; Tumor Cells, Cultured

1999
Apparatus and method for interfacing capillary electrophoresis and chemiluminescence nitrogen detection for the analysis of nitrogen-containing compounds.
    Journal of chromatography. A, 2000, Jan-28, Volume: 868, Issue:1

    Topics: Aminosalicylic Acid; Electrophoresis, Capillary; Luminescent Measurements; Nitrogen; Phenylalanine; Sensitivity and Specificity

2000
Enhancement of the specificity of an enzyme-based biosensor for L-tryptophan.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Biosensing Techniques; Electrochemistry; Enzymes, Immobilized; Escherichia coli; Kinetics; Phenylalanine; Pseudomonas; Recombinant Proteins; Sensitivity and Specificity; Tryptophan; Tryptophan Hydroxylase

1999
Comparison of two different methods for measurement of phenylalanine in dried blood spots.
    Clinical chemistry and laboratory medicine, 2000, Volume: 38, Issue:8

    Topics: Amino Acid Oxidoreductases; Humans; Neonatal Screening; Phenylalanine; Phenylketonurias; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity

2000
Use of the phenylalanine:tyrosine ratio to test newborns for phenylketonuria in a large public health screening programme.
    Journal of medical screening, 2000, Volume: 7, Issue:3

    Topics: California; Chromatography, High Pressure Liquid; Humans; Infant, Newborn; Laboratories; Neonatal Screening; Phenylalanine; Phenylketonurias; Pilot Projects; Reproducibility of Results; Sensitivity and Specificity; Tyrosine

2000
Effect of mobile phase acidic additives on enantioselectivity for phenylalanine analogs.
    Journal of chromatography. A, 2001, Aug-24, Volume: 927, Issue:1-2

    Topics: Acids; Phenylalanine; Sensitivity and Specificity; Stereoisomerism

2001
Polyester microchannel chip for electrophoresis--incorporation of a blue LED as light source.
    Fresenius' journal of analytical chemistry, 2001, Volume: 371, Issue:2

    Topics: Amino Acids; Electrophoresis; Equipment Design; Fiber Optic Technology; Fluorescence; Microchemistry; Optical Fibers; Phenylalanine; Polyesters; Sensitivity and Specificity; Valine

2001
[Determination of total phenylalanine and galactose from a sample of dry blood on paper filter: its application on neonatal screening].
    Biomedica : revista del Instituto Nacional de Salud, 2002, Volume: 22, Issue:1

    Topics: Blood Stains; Enzyme-Linked Immunosorbent Assay; Galactose; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Reference Values; Sensitivity and Specificity

2002
Glutamine transaminase K and cysteine S-conjugate beta-lyase activity stains.
    Analytical biochemistry, 1991, Sep-02, Volume: 197, Issue:2

    Topics: Animals; Cysteine; Electrophoresis, Polyacrylamide Gel; Kidney; Lyases; Methionine; Molecular Weight; Nitroblue Tetrazolium; Phenylalanine; Rats; Rats, Inbred Strains; Sensitivity and Specificity; Staining and Labeling; Transaminases

1991
Newborn screening for hyperphenylalaninemia on day 5: is 240 mumol/liter the most appropriate cut-off level?
    Preventive medicine, 1990, Volume: 19, Issue:1

    Topics: Germany, West; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Predictive Value of Tests; Prospective Studies; Sensitivity and Specificity; Time Factors

1990
A new approach to the newborn screening for hyperphenylalaninemias: use of L-phenylalanine dehydrogenase and microtiter plates.
    Clinica chimica acta; international journal of clinical chemistry, 1990, Dec-03, Volume: 192, Issue:3

    Topics: Amino Acid Oxidoreductases; Colorimetry; Humans; Infant, Newborn; Neonatal Screening; Paper; Phenylalanine; Phenylketonurias; Sensitivity and Specificity

1990