phenylalanine has been researched along with Sensitivity and Specificity in 119 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (0.84) | 18.7374 |
1990's | 29 (24.37) | 18.2507 |
2000's | 60 (50.42) | 29.6817 |
2010's | 26 (21.85) | 24.3611 |
2020's | 3 (2.52) | 2.80 |
Authors | Studies |
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B, S; B, VR; K, MN; Sharma, H; Yerra, S | 1 |
Maugeri, L; Messina, MA; Petralia, S; Puccio, R; Ruggieri, M; Spoto, G | 1 |
Akita, T; Furusho, A; Hamase, K; Hsiao, SW; Hsieh, CL; Ide, T; Ishii, C; Konno, R; Lee, CK; Mita, M; Okamura, T; Shimizu, Y | 1 |
Dodda, S; Kandhagatla, RN; Makula, A; Polagani, SR | 1 |
Ahmad, I; Ashraf, R; Khan, A; Khan, S; Ullah, R | 1 |
Jeong, JS; Kim, SK; Park, SR | 1 |
Ingenito, L; Parenti, G; Pecce, R; Ruoppolo, M; Scolamiero, E | 1 |
Fang, HX; Liu, XY; Yu, LP | 1 |
Hattori, T; Ishikawa, A; Ohki, H; Saito, K; Yabe, T; Yoshino, K | 1 |
Eisenhower, C; Erlich, P; Ferrari, A; Irvin-Barnwell, EA; Patel, MD; Roda, P; Tang, X | 1 |
Chen, JJ; Fu, YY; Huang, H; Li, Q; Liu, Z; Mu, J; Wei, YD; Xie, P; Yang, DY; Zheng, P; Zhou, CJ; Zhou, JJ | 1 |
Acevedo, AC; Chardin, H; De Luca Canto, G; Gozal, D; Guerra, EN; Leite, AF | 1 |
Bereczky, Z; Boda, Z; Gindele, R; Ilonczai, P; Kovács, B; Marján, E; Muszbek, L; Oláh, Z; Pfliegler, G; Selmeczi, A; Speker, M; Udvari, Á | 1 |
Armutlulu, A; Balaram, H; Balasubramanian, S; Bartosh, TJ; Broda, M; Brown, LE; Burroughs, LM; Burrows, F; Cardoso, JR; Carregaro, RL; Cho, J; Cui, Q; Dela Bela, LF; Dias, JM; Dutta, NK; Flowers, ME; Gallo, S; Hari, P; He, R; He, Y; Heimfeld, S; Jia, B; Jin, X; Jin, YJ; Karakousis, PC; Karmakar, T; Kiem, HP; Kreager, DA; Lebedev, D; Li, F; Li, S; Liang, N; Liu, Z; Luo, J; Luo, Y; Mazuquin, BF; Meng, Y; Mosialos, G; Moura, FA; Müller, CR; Naeem, MA; Nagappa, LK; Nguyen, H; Pelegrinelli, AR; Pinn, ML; Prahlada Rao, VS; Pulsipher, MA; Ragan, DT; Richards, J; Roy, S; Sandmaier, BM; Selfe, J; Selim, MA; Shi, J; Shi, X; Staff, J; Storb, R; Storer, BE; Wang, F; Wang, M; Wang, S; Woolfrey, AE; Wright, T; Ylostalo, JH; Zhang, JY; Zhang, ZY; Zheng, K; Zhu, Z | 1 |
Borghei, YS; Ganjali, MR; Hosseini, M; Khoobi, M | 1 |
Gopalan, AI; Lee, KP; Manesh, KM; Santhosh, P; Uthayakumar, S | 1 |
Arteaga, AL; Castells, E; del Río, L; Frómeta, A; García, SM; González, EC; Licourt, T; Martínez, L; Robaina, MS | 1 |
Chang, SM; Guo, HS; Kim, JM; Kim, WS | 2 |
Boesch, C; Kreis, R; Nuoffer, JM; Zwygart, K | 1 |
Fujii, N; Fukutani, S; Kashino, G; Kinashi, Y; Liu, Y; Maruhashi, A; Masunaga, S; Nagata, K; Ono, K; Sakurai, Y; Suzuki, M; Tanaka, H | 1 |
Hong, SP; Jeong, JS; Lee, DH; Lee, YM; Sim, HJ; Yoon, HR | 1 |
Gu, W; Hu, X; Liang, J; Sun, J; Wen, Z; Xu, Y; Zhao, T | 1 |
Anouti, S; Cottet, H; Vandenabeele-Trambouze, O | 1 |
Ayar-Kayali, H; Tarhan, L | 1 |
Farmakis, G; Grgic, A; Hellwig, D; Ketter, R; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S; Schaefer, A; Steudel, WI | 1 |
Cao, KW; Chen, XF; Chu, QC; Li, WL; Tang, WR; Ye, JN; Zhang, DL; Zhang, JB | 1 |
Alexiou, GA; Fotopoulos, AD; Kyritsis, AP; Tsiouris, S; Voulgaris, S | 1 |
Hofstetter, H; Hofstetter, O; Kassa, T; Undesser, LP | 1 |
Hong, SP; Jeong, JS; Kwon, HJ; Lee, YM; Sim, HJ; Yoon, HR | 1 |
Cho, SH; Duin, EC; Hong, JW; Jambovane, S; Kim, SK; Yun, JY | 1 |
Kirito, K; Koda, AH; Komatsu, N; Morishita, S; Noda, N; Sekiguchi, Y; Tsuneda, S | 1 |
Yan, HT; Zhang, K; Zhou, T | 1 |
Asai, S; Ishii, Y; Murai, I; Suzuki, S | 1 |
Ross, LF | 1 |
Allen, LJ; Harrison, RG; Lamb, JD; Li, N | 1 |
Baynes, JW; Carson, JA; Enos, RT; Lima, M; Sato, S | 1 |
Bührdel, P; Ceglarek, U; Kiess, W; Müller, P; Stach, B; Thiery, J | 1 |
Bongaerts, J; Bujnicki, R; Ganpo-Nkwenkwa, E; Gerigk, M; Sprenger, G; Takors, R | 1 |
Buhr, HJ; Foitzik, T; Hines, OJ; Hotz, B; Hotz, HG; Reber, HA | 1 |
Bandmann, O; Deuschl, G; Goertz, M; Hefter, H; Hoffmann, G; Jost, W; Müller, U; Oertel, W; Zöfel, P; Zschocke, J | 1 |
Dale, Y; Ike, J; Mackey, V; Maleque, M; Mushi, R; Nyanda, A | 1 |
Alen, M; Keinanen, O; Knuutinen, J; Komi, PV; Lahti, K; Mero, AA; Nykanen, T; Pitkanen, HT | 1 |
Hirata, N; Kuriyama, T; Yamawaki, N | 1 |
Albright, R; Cobelli, C; Dietz, N; Joyner, M; Nair, KS; Toffolo, G | 1 |
Meerman, JH; Orhan, H; Tump, C; Vermeulen, NP; Zappey, H | 1 |
Amon, M; Feiden, W; Hellwig, D; Kirsch, CM; Kubuschok, B; Menger, MD; Romeike, BF; Samnick, S | 1 |
Aleshin, AN; Matsuda, H; Miyamoto, Y; Ono, M; Ryugo, M; Sawa, Y | 1 |
Brown, EM; Conigrave, AD; Delbridge, L; Mun, HC; Quinn, SJ; Wilkinson, M | 1 |
Chen, Y; Qiao, F; Yan, H; Yang, G | 1 |
Chen, X; He, Z; Liu, X; Zhang, R; Zhao, C; Zhong, D | 1 |
Kobori, T; Toda, K; Yoshii, T | 1 |
Capodicasa, S; Colaiocco-Ferrante, L; Colecchia, A; Festi, D; Mazzella, G; Portincasa, P; Roda, E; Sandri, L; Simoni, P; Staniscia, T; Vestito, A; Vitacolonna, E | 1 |
Oldiges, M; Takors, R | 1 |
Iwai, M; Kato, A; Koeda, N; Suzuki, K | 1 |
Clifton-Bligh, RJ; Collyer, CA; Conigrave, AD; Culverston, EL; Franks, AH; Mun, HC | 1 |
Hellwig, D; Ketter, R; Kirsch, CM; Moringlane, JR; Romeike, BF; Samnick, S; Schaefer, A; Sell, N | 1 |
Farnsworth, PB; Lee, ML; Li, L; Paul, UP | 1 |
Deng, C; Yin, X; Zhang, L; Zhang, X | 1 |
Gu, XF; Han, LS; Qiu, WJ; Ye, J; Zhang, ZX | 1 |
Lioe, H; O'Hair, RA | 1 |
Ballhausen, D; Baumgartner, M; Blau, N; Bonafé, L; Fiege, B; Fiori, L; Giovannini, M; Meili, D; Thöny, B | 1 |
Betti, M; Carlos, R; Cionini, L; de las Heras, LA; Lazzerini, G; Menichetti, L; Pitois, A; Salvatori, PA; Zampolli, A | 1 |
Moeini, H; Vallian, S | 1 |
Baum, F; Behbehani, AW; Langenbeck, U; Luthe, H; Mench-Hoinowski, A | 1 |
Cornelissen, B; De Spiegeleer, B; Dierckx, RA; Kersemans, K; Kersemans, V; Mertens, J; Slegers, G | 1 |
De Spiegeleer, B; Kersemans, V; Mertens, J; Slegers, G | 1 |
Ahmed, M; Jimenez-Cruz, M; Leone, SR; Peterka, DS; Wilson, KR | 1 |
Alifrangis, M; Drakeley, C; Kulkarni, MA; Kweka, E; Lyimo, I; Magesa, S; Malima, R; Matowo, J; Mosha, FW; Peter, J; Rau, ME; Rowland, M; Salanti, A | 1 |
Brettel, K; Byrdin, M; Eker, AP; Lukacs, A; Pan, J; Villette, S; Vos, MH | 1 |
Dorris, M; Loh, A; Peterson, L; Weiss, DJ | 1 |
Asano, Y; Suzuki, M; Tachibana, S | 1 |
Abe, R; Hohsaka, T; Iijima, I; Kajihara, D; Komiyama, C; Sisido, M | 1 |
Ajami, D; Rebek, J; Schramm, MP; Volonterio, A | 1 |
Asano, Y; Cao, R; Fujii, A; Ortiz, P; Shinohara, H; Tachibana, S; Villalonga, R | 1 |
Carnley, B; Hammond, E; Herrmann, R; James, I; P'ng, S; Shaw, K | 1 |
Chen, Q; Cross, NC; Jones, AV; Lu, P; Silver, RT; Wang, YL | 1 |
Mashru, RC; Sankalia, JM; Sankalia, MG; Sutariya, VB | 1 |
Matthews, AJ; Pollitt, RJ | 1 |
Bauwens, M; Bossuyt, A; Caveliers, V; Kersemans, K; Keyaerts, M; Lahoutte, T; Mertens, J | 1 |
Hayashida, O; Ogawa, N; Uchiyama, M | 1 |
Boesch, C; Kreis, R; Lutz, T; Pietz, J; Robert-Tissot, L; Vermathen, P | 1 |
Dahlsten, E; Korkeala, H; Lindström, M; Somervuo, P | 1 |
Hammen, HW; Matthiesen, U; Schadewaldt, P; Wendel, U | 1 |
Geiger, R; Miska, W; Monsees, T | 1 |
Chace, DH; Hillman, SL; Kahler, SG; Millington, DS; Naylor, EW; Roe, CR | 1 |
Bock, D; Diepenbrock, F; Heckler, R; Lubenow, N; Sander, J; Schickling, H | 1 |
Denmeade, R; Green, A; Keffler, S | 1 |
Colley, CM; Rakhorst, S; Tillyer, CR | 1 |
Agarwal, KC; Beylot, M; Brunengraber, H; Soloviev, MV; Yang, D | 1 |
Binette, F; Crawford, K; Goetinck, PF; Millán, JL; Weissig, H | 1 |
Lehotay, DC; Randell, EW | 1 |
Kanno, S; Matsuda, K; Ono, I | 1 |
Asano, Y; Cooper, AJ; Fujii, T; Kato, Y; Nakamura, K | 1 |
Pronce, T; Tilquin, B | 1 |
Fresta, M; Micali, N; Puglisi, G; Trusso, S; Villari, A | 1 |
Beierwaltes, W; Froelich, J; Gonin, J; Macfarlane, D; Mangner, T; Shapiro, B; Wieland, D | 1 |
Dey, S; Karthikeyan, S; Mitra, SN; Singh, TP | 1 |
Fitzpatrick, PF; Rainina, EI; Simonian, AL; Wild, JR | 1 |
Leeming, RJ | 1 |
Allen, MC; Nocerini, MR; Stafford, CG | 1 |
Donner, K; Fyhrquist, N; Hargrave, PA; McDowell, JH; Popp, MP; Smith, WC | 1 |
Cipriano, A; Maniara, WM; Powell, ML | 1 |
Rehfeld, JF | 1 |
Ao, A; Handyside, AH; Ray, PF; Taylor, DM; Winston, RM | 1 |
Kohlmueller, D; Mayatepek, E; Schulze, A | 1 |
Akaboshi, M; Kinashi, Y; Kobayashi, T; Masunaga, S; Ono, K; Sakurai, Y; Suzuki, M; Takagaki, M | 1 |
Fujinari, E; Mohammad, AA; Okorodudu, AO; Petersen, JR | 1 |
Fitzpatrick, PF; Rainina, EI; Simonian, AL; Wild, J | 1 |
Allué, JA; Grijalba, A; Merlo, SG; Palacios, M; Rivero, A | 1 |
Cunningham, G; Currier, RJ; Eastman, JW; Liao, CL; Lorey, F; Sherwin, JE; Wong, R | 1 |
Färkkilä, M; Kallio, M; Kulvik, M; Laakso, J; Ruokonen, I; Vähätalo, J; Zilliacus, R | 1 |
Stringham, RW; Ye, YK | 1 |
Hobo, T; Qiu, J; Uchiyama, K; Xu, W | 1 |
Baloy, A; Fernández, L; Frómeta, A; Torres, E | 1 |
Abraham, DG; Cooper, AJ | 1 |
Ledley, FD | 1 |
Burmester, JG; Clemens, PC; Neumann, SJ; Wulke, AP | 1 |
Hummel, W; Koppelkamm, M; Langenbeck, U; Sander, J; Wendel, U | 1 |
3 review(s) available for phenylalanine and Sensitivity and Specificity
Article | Year |
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Diagnostic capability of salivary biomarkers in the assessment of head and neck cancer: A systematic review and meta-analysis.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Carbocysteine; Choline; Head and Neck Neoplasms; Humans; Interleukin-8; Middle Aged; Phenylalanine; Piperidines; Saliva; Sensitivity and Specificity; Young Adult | 2015 |
Immusorba TR and PH.
Topics: Absorption; Acetylcholine; Arthritis, Rheumatoid; Autoantibodies; Biocompatible Materials; Clinical Trials as Topic; Equipment Design; Equipment Safety; Guillain-Barre Syndrome; Humans; Immunosorbent Techniques; Immunosorbents; Lupus Erythematosus, Systemic; Myasthenia Gravis; Phenylalanine; Sensitivity and Specificity; Tryptophan | 2003 |
Clinical application of genotypic diagnosis for phenylketonuria: theoretical considerations.
Topics: Genotype; Humans; Mutation; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Sensitivity and Specificity | 1991 |
4 trial(s) available for phenylalanine and Sensitivity and Specificity
Article | Year |
---|---|
The phenylalanine loading test in the differential diagnosis of dystonia.
Topics: Administration, Oral; Adult; Diagnosis, Differential; Dystonia; Female; Humans; Levodopa; Male; Middle Aged; Phenylalanine; Predictive Value of Tests; Reference Values; Sensitivity and Specificity; Time Factors; Tyrosine | 2003 |
Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Breath Tests; Carbon Isotopes; Female; Hepatitis, Chronic; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Phenylalanine; Prognosis; Sensitivity and Specificity | 2005 |
Validation of brain tumour imaging with p-[123I]iodo-L-phenylalanine and SPECT.
Topics: Adult; Aged; Brain Neoplasms; Female; Humans; Male; Middle Aged; Phenylalanine; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2005 |
Atomic emission method for total boron in blood during neutron-capture therapy.
Topics: Adult; Aged; Boron; Boron Compounds; Boron Neutron Capture Therapy; Female; Hematocrit; Humans; Indicators and Reagents; Male; Mass Spectrometry; Middle Aged; Phenylalanine; Sensitivity and Specificity; Spectrophotometry, Atomic | 2001 |
112 other study(ies) available for phenylalanine and Sensitivity and Specificity
Article | Year |
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A novel stability-indicating HPLC method for the determination of enantiomeric purity of eluxadoline drug: Amylose tris(3,5-dichlorophenyl carbamate) stationary phase.
Topics: Amylose; Chromatography, High Pressure Liquid; Drug Stability; Imidazoles; Linear Models; Phenylalanine; Phenylcarbamates; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism | 2022 |
Fully Integrated Point-of-Care Platform for the Self-Monitoring of Phenylalanine in Finger-Prick Blood.
Topics: Humans; Phenylalanine; Phenylketonurias; Point-of-Care Systems; Reproducibility of Results; Sensitivity and Specificity | 2023 |
Determination of phenylalanine enantiomers in the plasma and urine of mammals and ᴅ-amino acid oxidase deficient rodents using two-dimensional high-performance liquid chromatography.
Topics: Animals; Animals, Genetically Modified; Chromatography, High Pressure Liquid; D-Amino-Acid Oxidase; Humans; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Phenylalanine; Rats; Rats, Inbred F344; Sensitivity and Specificity; Stereoisomerism; Young Adult | 2021 |
High sensitive LC-MS/MS method for estimation of eluxadoline in human plasma and its application to pharmacokinetic study.
Topics: Chromatography, Liquid; Gastrointestinal Agents; Glucuronides; Humans; Imidazoles; India; Male; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry | 2019 |
Optical screening of hepatitis-B infected blood sera using optical technique and neural network classifier.
Topics: Bilirubin; Hepatitis B; Humans; Neural Networks, Computer; Pakistan; Phenylalanine; Predictive Value of Tests; Sensitivity and Specificity; Serum Albumin; Spectrum Analysis, Raman; Tryptophan | 2019 |
Amino acid analysis of dried blood spots for diagnosis of phenylketonuria using capillary electrophoresis-mass spectrometry equipped with a sheathless electrospray ionization interface.
Topics: Amino Acids; Dried Blood Spot Testing; Electrophoresis, Capillary; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2013 |
Optimization of an HPLC method for phenylalanine and tyrosine quantization in dried blood spot.
Topics: Adolescent; Chromatography, High Pressure Liquid; Dried Blood Spot Testing; Humans; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity; Tyrosine; Young Adult | 2013 |
Molecularly imprinted photonic polymer based on β-cyclodextrin for amino acid sensing.
Topics: Acrylates; beta-Cyclodextrins; Crystallization; Hydrogen-Ion Concentration; Maleic Anhydrides; Molecular Imprinting; Phenylalanine; Photons; Polymerization; Polystyrenes; Sensitivity and Specificity; Stereoisomerism; Temperature | 2013 |
(10)B-NMR determination of (10)B-BPA, (10)B-BPA-fructose complex and total (10)B in blood for BNCT.
Topics: Blood Chemical Analysis; Boron; Boron Compounds; Boron Neutron Capture Therapy; Fructose; Humans; Isotopes; Magnetic Resonance Spectroscopy; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity | 2014 |
Determination of accuracy of polycythemia vera diagnoses and use of the JAK2V617F test in the diagnostic scheme.
Topics: Amino Acid Substitution; Diagnostic Errors; DNA Mutational Analysis; Genetic Testing; Humans; Janus Kinase 2; Mutation, Missense; Myeloproliferative Disorders; Phenylalanine; Polycythemia Vera; Registries; Retrospective Studies; Sensitivity and Specificity; Valine | 2014 |
Divergent Urinary Metabolic Phenotypes between Major Depressive Disorder and Bipolar Disorder Identified by a Combined GC-MS and NMR Spectroscopic Metabonomic Approach.
Topics: Adult; beta-Alanine; Biomarkers; Bipolar Disorder; Depressive Disorder, Major; Diagnosis, Differential; Female; Formates; Gas Chromatography-Mass Spectrometry; Humans; Hydroxybutyrates; Magnetic Resonance Spectroscopy; Male; Metabolome; Metabolomics; Phenylalanine; Propionates; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Young Adult | 2015 |
Founder effect is responsible for the p.Leu131Phe heparin-binding-site antithrombin mutation common in Hungary: phenotype analysis in a large cohort.
Topics: Adolescent; Adult; Aged; Antithrombins; Arteries; Binding Sites; Child; Child, Preschool; Cohort Studies; Factor Xa; Female; Founder Effect; Genetic Association Studies; Heparin; Heterozygote; Humans; Hungary; Leucine; Microsatellite Repeats; Middle Aged; Mutation; Phenotype; Phenylalanine; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications, Cardiovascular; Sensitivity and Specificity; Thrombosis; Young Adult | 2016 |
Topics: Adolescent; Adult; Age Factors; Aged; Amino Acid Substitution; Anemia, Aplastic; Athletes; Athletic Performance; Bone Marrow Transplantation; Carcinoma, Non-Small-Cell Lung; Catalytic Domain; Cell Count; Child; Child, Preschool; Escherichia coli; Female; Gene Expression; Graft Survival; Graft vs Host Disease; Histocompatibility Testing; Humans; Hydrogen Bonding; Immunosuppression Therapy; Inosine Monophosphate; Integrin alphaVbeta3; Kinetics; Knee Joint; Lung Neoplasms; Lymphatic Metastasis; Male; Mediastinal Neoplasms; Middle Aged; Molecular Dynamics Simulation; Muscle, Skeletal; Mutation; Organotechnetium Compounds; Pentosyltransferases; Peptides, Cyclic; Phenylalanine; Plasmodium falciparum; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protozoan Proteins; Radiopharmaceuticals; Recombinant Proteins; Running; Sensitivity and Specificity; Serine; Siblings; Single Photon Emission Computed Tomography Computed Tomography; Soccer; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Threonine; Time Factors; Torque; Treatment Outcome; Tryptophan; Tyrosine; Young Adult | 2016 |
Copper nanocluster-enhanced luminol chemiluminescence for high-selectivity sensing of tryptophan and phenylalanine.
Topics: Copper; Humans; Luminescence; Luminescent Measurements; Luminol; Phenylalanine; Sensitivity and Specificity; Tryptophan | 2017 |
Hollow spherical nanostructured polydiphenylamine for direct electrochemistry and glucose biosensor.
Topics: Biosensing Techniques; Dipeptides; Electrochemistry; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Glucose; Glucose Oxidase; Microelectrodes; Nanostructures; Nanotechnology; Phenylalanine; Polymers; Porosity; Reproducibility of Results; Sensitivity and Specificity | 2009 |
Cuban neonatal screening of phenylketonuria using an ultramicro-fluorometric test.
Topics: Blood Specimen Collection; Cuba; Fluorometry; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Sensitivity and Specificity | 2009 |
Chiral recognition of mandelic acid by L-phenylalanine-modified sensor using quartz crystal microbalance.
Topics: Biosensing Techniques; Electrochemistry; Isomerism; Mandelic Acids; Microtechnology; Phenylalanine; Quartz; Sensitivity and Specificity; Surface Properties | 2009 |
Reproducibility of cerebral phenylalanine levels in patients with phenylketonuria determined by 1H-MR spectroscopy.
Topics: Adolescent; Adult; Biomarkers; Brain; Child; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phenylalanine; Phenylketonurias; Protons; Reproducibility of Results; Sensitivity and Specificity; Young Adult | 2009 |
Chiral recognition of mandelic acid on quartz crystal microbalance by vapor diffused molecular assembly method.
Topics: Biosensing Techniques; Gold; Isomerism; Mandelic Acids; Phenylalanine; Quartz; Sensitivity and Specificity; Surface Properties | 2009 |
A simple and rapid method for measurement of (10)B-para-boronophenylalanine in the blood for boron neutron capture therapy using fluorescence spectrophotometry.
Topics: Animals; Biological Assay; Blood Chemical Analysis; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Humans; Mice; Mice, Inbred C3H; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Sulfhydryl Compounds | 2009 |
Determination of phenylalanine in blood by high-performance anion-exchange chromatography-pulsed amperometric detection to diagnose phenylketonuria.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Sensitivity and Specificity | 2009 |
A microsystem of low-voltage-driven electrophoresis on microchip with array electrode pairs for the separation of amino acids.
Topics: Dimethylpolysiloxanes; Electrochemistry; Electrodes; Electrophoresis, Capillary; Lysine; Microfluidics; Phenylalanine; Sensitivity and Specificity; Silicon; Temperature; Time Factors | 2009 |
Heart-cutting 2D-CE with on-line preconcentration for the chiral analysis of native amino acids.
Topics: Amino Acids; Crown Ethers; Electrophoresis, Capillary; Formates; Phenylalanine; Sensitivity and Specificity; Stereoisomerism; Threonine | 2010 |
Immobilization of phenylalanine dehydrogenase and its application in flow-injection analysis system for determination of plasma phenylalanine.
Topics: Amino Acid Oxidoreductases; Bioreactors; DEAE-Cellulose; Diamines; Enzymes, Immobilized; Flow Injection Analysis; Glutaral; Humans; Hydrogen-Ion Concentration; Kinetics; NAD; Phenylalanine; Phenylketonurias; Sensitivity and Specificity; Sporosarcina; Temperature | 2011 |
Prospective study of p-[123I]iodo-L-phenylalanine and SPECT for the evaluation of newly diagnosed cerebral lesions: specific confirmation of glioma.
Topics: Brain Neoplasms; Female; Glioma; Humans; Male; Middle Aged; Phenylalanine; Prospective Studies; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2010 |
Determination of unconjugated aromatic acids in urine by capillary electrophoresis with dual electrochemical detection--potential application in fast diagnosis of phenylketonuria.
Topics: Adult; Biomarkers; Electrodes; Electrophoresis, Capillary; Female; Humans; Hydrogen-Ion Concentration; Infant; Linear Models; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Reproducibility of Results; Sensitivity and Specificity; Sodium Dodecyl Sulfate | 2010 |
99mTc-tetrofosmin SPECT for the evaluation of cerebral lesions.
Topics: Brain Neoplasms; Humans; Organophosphorus Compounds; Organotechnetium Compounds; Phenylalanine; Prospective Studies; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon | 2010 |
Antibody-based multiplex analysis of structurally closely related chiral molecules.
Topics: Fluorescent Antibody Technique; Lactic Acid; Microarray Analysis; Phenylalanine; Sensitivity and Specificity; Stereoisomerism | 2011 |
Chromatographic diagnosis of maple syrup urine disease by measuring the L-alloisoleucine/L-phenylalanine ratio in dried blood spots.
Topics: Adult; Blood Specimen Collection; Chromatography, High Pressure Liquid; Humans; Infant, Newborn; Isoleucine; Male; Maple Syrup Urine Disease; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity | 2011 |
Log-scale dose response of inhibitors on a chip.
Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Inhibitory Concentration 50; Kinetics; Lab-On-A-Chip Devices; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Microchip Analytical Procedures; Neoplasms; Phenylalanine; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiophenes | 2011 |
Alternately binding probe competitive PCR as a simple, cost-effective, and accurate quantification method for JAK2V617F allele burden in myeloproliferative neoplasms.
Topics: Alleles; Amino Acid Substitution; Binding, Competitive; Bone Marrow Neoplasms; Cell Line, Tumor; Cost-Benefit Analysis; DNA Mutational Analysis; DNA Probes; Gene Dosage; Humans; Janus Kinase 2; Models, Biological; Myeloproliferative Disorders; Phenylalanine; Polymerase Chain Reaction; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Valine | 2011 |
Spectrofluorimetric determination of phenylalanine based on fluorescence enhancement of europium ion immobilized with sol-gel method.
Topics: Equipment Design; Europium; Filtration; Humans; Hydrogen-Ion Concentration; Phase Transition; Phenylalanine; Sensitivity and Specificity; Spectrometry, Fluorescence | 2011 |
Liver function assessment with three (13)C breath tests by two-point measurements.
Topics: Acetamides; Aged; Breath Tests; Carbon Dioxide; Carbon Isotopes; Female; Hepatitis, Chronic; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methionine; Middle Aged; Phenylalanine; Sensitivity and Specificity | 2012 |
50 years ago in the Journal of Pediatrics: comparison of serum phenylalanine levels with growth in Guthrie's inhibition assay in newborn infants.
Topics: History, 20th Century; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Sensitivity and Specificity; Tandem Mass Spectrometry | 2012 |
Transition metal cation separations with a resorcinarene-based amino acid stationary phase.
Topics: Alanine; Amino Acids; Calixarenes; Carboxylic Acids; Cations, Divalent; Chelating Agents; Chromatography, Ion Exchange; Macrocyclic Compounds; Metals; Phenylalanine; Sensitivity and Specificity; Transition Elements | 2013 |
Development of an UPLC mass spectrometry method for measurement of myofibrillar protein synthesis: application to analysis of murine muscles during cancer cachexia.
Topics: Adenomatous Polyposis Coli; Animals; Biomarkers; Biopsy; Cachexia; Chromatography, Liquid; Diaphragm; Down-Regulation; Genes, APC; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle Proteins; Muscle, Skeletal; Myofibrils; Phenylalanine; Proteomics; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors | 2013 |
Validation of the phenylalanine/tyrosine ratio determined by tandem mass spectrometry: sensitive newborn screening for phenylketonuria.
Topics: Blood Specimen Collection; Chromatography, Ion Exchange; Fluorometry; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2002 |
Process control for enhanced L-phenylalanine production using different recombinant Escherichia coli strains.
Topics: Bioreactors; Cells, Cultured; Escherichia coli; Feedback; Glucose; Homeostasis; Phenylalanine; Pilot Projects; Quality Control; Recombinant Proteins; Recombination, Genetic; Reproducibility of Results; Sensitivity and Specificity; Species Specificity; Tyrosine | 2002 |
Evaluation of vascular endothelial growth factor blockade and matrix metalloproteinase inhibition as a combination therapy for experimental human pancreatic cancer.
Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Chi-Square Distribution; Disease Models, Animal; Drug Therapy, Combination; Endothelial Growth Factors; Humans; Intercellular Signaling Peptides and Proteins; Lymphokines; Male; Matrix Metalloproteinases; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Pancreatic Neoplasms; Phenylalanine; Probability; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric; Thiophenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Simultaneous measurement of phenylalanine and tyrosine in phenylketonuric plasma and dried blood by high-performance liquid chromatography.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Female; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tyrosine | 2003 |
Free amino acid pool and muscle protein balance after resistance exercise.
Topics: Adult; Amino Acids, Essential; Biological Transport; Case-Control Studies; Exercise; Humans; Leg; Male; Multivariate Analysis; Muscle Proteins; Muscle, Skeletal; Oxygen Consumption; Phenylalanine; Physical Exertion; Probability; Reference Values; Regional Blood Flow; Sensitivity and Specificity; Weight Lifting | 2003 |
Model to assess muscle protein turnover: domain of validity using amino acyl-tRNA vs. surrogate measures of precursor pool.
Topics: Adult; Arteries; Biological Transport; Carbon Isotopes; False Negative Reactions; False Positive Reactions; Humans; Keto Acids; Kinetics; Leucine; Mathematics; Models, Biological; Muscle Proteins; Muscle, Skeletal; Nitrogen Isotopes; Phenylalanine; RNA, Transfer, Amino Acyl; Sensitivity and Specificity; Veins | 2003 |
Simultaneous determination of tyrosine, phenylalanine and deoxyguanosine oxidation products by liquid chromatography-tandem mass spectrometry as non-invasive biomarkers for oxidative damage.
Topics: Calibration; Chromatography, Gas; Chromatography, High Pressure Liquid; Deoxyguanosine; Humans; Mass Spectrometry; Oxidative Stress; Phenylalanine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tyrosine | 2004 |
p-[123I]iodo-L-phenylalanine for detection of pancreatic cancer: basic investigations of the uptake characteristics in primary human pancreatic tumour cells and evaluation in in vivo models of human pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Drug Evaluation, Preclinical; Humans; Metabolic Clearance Rate; Mice; Mice, SCID; Organ Specificity; Pancreatic Neoplasms; Phenylalanine; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution | 2004 |
Pharmacologic preconditioning of JTE-607, a novel cytokine inhibitor, attenuates ischemia-reperfusion injury in the myocardium.
Topics: Animals; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Phenylalanine; Piperazines; Probability; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Survival Rate | 2004 |
L-amino acids regulate parathyroid hormone secretion.
Topics: Amino Acids; Calcium; Cytoplasm; Dose-Response Relationship, Drug; Humans; Ions; Magnesium; Parathyroid Glands; Parathyroid Hormone; Phenylalanine; Receptors, Calcium-Sensing; Sensitivity and Specificity; Spermine; Time Factors; Tryptophan | 2004 |
Determination of nateglinide in animal plasma by micellar electrokinetic chromatography and on-line sweeping technique.
Topics: Animals; Buffers; Chromatography, Micellar Electrokinetic Capillary; Cyclohexanes; Hydrogen-Ion Concentration; Nateglinide; Phenylalanine; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling | 2004 |
Study on the bioavailability of nateglinide-hydroxypropyl-beta-cyclodextrin complex capsule in rabbits by liquid chromatographic-tandem mass spectrometry.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Biological Availability; Capsules; Chemistry, Pharmaceutical; Chromatography, Liquid; Cyclohexanes; Male; Mass Spectrometry; Nateglinide; Phenylalanine; Quality Control; Rabbits; Sensitivity and Specificity | 2004 |
Phenylalanine hydroxylase deficiency in the peripheral lymphocytes from phenylketonuria.
Topics: Autoradiography; Case-Control Studies; Cells, Cultured; Female; Humans; Japan; Lymphocytes; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Reference Values; Sampling Studies; Sensitivity and Specificity; Tyrosine | 1977 |
Applying metabolic profiling techniques for stimulus-response experiments: chances and pitfalls.
Topics: Algorithms; Bioreactors; Escherichia coli; Escherichia coli Proteins; Flow Injection Analysis; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Models, Biological; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity; Signal Transduction; Stochastic Processes | 2005 |
Validity of 13C-phenylalanine breath test to evaluate functional capacity of hepatocyte in patients with liver cirrhosis and acute hepatitis.
Topics: Acute Disease; Breath Tests; Female; Hepatitis; Hepatocytes; Humans; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Phenylalanine; Sensitivity and Specificity | 2005 |
A double mutation in the extracellular Ca2+-sensing receptor's venus flytrap domain that selectively disables L-amino acid sensing.
Topics: Allosteric Site; Amino Acids; Aminoacylation; Blotting, Western; Calcium; Cell Line; Cytoplasm; DNA Mutational Analysis; Humans; Kinetics; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Receptors, Calcium-Sensing; Sensitivity and Specificity; Time Factors; Transfection | 2005 |
Compact detector for proteins based on two-photon excitation of native fluorescence.
Topics: Animals; Cattle; Equipment Design; Equipment Failure Analysis; Fluorescence; Lab-On-A-Chip Devices; Lasers; Microchip Analytical Procedures; Optics and Photonics; Phenylalanine; Photons; Sensitivity and Specificity; Serum Albumin, Bovine; Time Factors; Tryptophan; Tyrosine | 2005 |
Development of microwave-assisted derivatization followed by gas chromatography/mass spectrometry for fast determination of amino acids in neonatal blood samples.
Topics: Amino Acids; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Microwaves; Phenylalanine; Phenylketonurias; Sensitivity and Specificity; Time Factors; Tyrosine | 2005 |
[Tetrahydrobiopterin loading test in differential diagnosis among hyperphenylalaninemia patients].
Topics: Biopterins; Diagnosis, Differential; Dihydropteridine Reductase; Female; Humans; Infant; Infant, Newborn; Male; Mass Screening; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Sensitivity and Specificity | 2005 |
Neighbouring group processes in the deamination of protonated phenylalanine derivatives.
Topics: Ammonia; Carbon Monoxide; Deamination; Models, Chemical; Molecular Structure; Phenylalanine; Protons; Sensitivity and Specificity; Stereoisomerism; Tandem Mass Spectrometry; Water | 2005 |
Extended tetrahydrobiopterin loading test in the diagnosis of cofactor-responsive phenylketonuria: a pilot study.
Topics: Biopterins; Humans; Male; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Sensitivity and Specificity | 2005 |
Capillary electrophoresis-electrospray mass spectrometry and HR-ICP-MS for the detection and quantification of 10B-boronophenylalanine (10B-BPA) used in boron neutron capture therapy.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Electrophoresis, Capillary; Endothelial Cells; Glioma; Humans; Isotopes; Mass Spectrometry; Molecular Structure; Phenylalanine; Rats; Sensitivity and Specificity; Time Factors | 2006 |
A quantitative bacterial micro-assay for rapid detection of serum phenylalanine in dry blood-spots: application in phenylketonuria screening.
Topics: Amino Acid Oxidoreductases; Blood Chemical Analysis; Chromatography, High Pressure Liquid; False Positive Reactions; Glutamates; Humans; Mass Screening; Phenylalanine; Phenylketonurias; Sensitivity and Specificity | 2006 |
Predicting the phenylalanine blood concentration from urine analyses. An approach to noninvasive monitoring of patients with phenylketonuria.
Topics: Adult; Analysis of Variance; Blood Chemical Analysis; Clinical Laboratory Techniques; Creatinine; Diet; Electroencephalography; Female; Humans; Male; Middle Aged; Models, Statistical; Mutation; Phenylalanine; Phenylketonurias; Regression Analysis; Sensitivity and Specificity; Time Factors | 2005 |
Comparative biodistribution study of the new tumor tracer [123I]-2-iodo-L-phenylalanine with [123I]-2-iodo-L-tyrosine.
Topics: Animals; Cell Line, Tumor; Female; Iodine Radioisotopes; Metabolic Clearance Rate; Mice; Monoiodotyrosine; Organ Specificity; Phenylalanine; Radiopharmaceuticals; Reproducibility of Results; Rhabdomyosarcoma; Sensitivity and Specificity; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2006 |
Influence of sedation and data acquisition method on tracer uptake in animal models: [123I]-2-iodo-L-phenylalanine in pentobarbital-sedated tumor-bearing athymic mice.
Topics: Animals; Artifacts; Cell Line, Tumor; Disease Models, Animal; Hypnotics and Sedatives; Image Interpretation, Computer-Assisted; Iodine Radioisotopes; Male; Metabolic Clearance Rate; Mice; Mice, Nude; Organ Specificity; Pentobarbital; Phenylalanine; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Rhabdomyosarcoma; Sensitivity and Specificity; Tissue Distribution | 2006 |
VUV photoelectron imaging of biological nanoparticles: ionization energy determination of nanophase glycine and phenylalanine-glycine-glycine.
Topics: Glycine; Ions; Kinetics; Models, Biological; Nanostructures; Nanotechnology; Particle Size; Phenylalanine; Photochemistry; Photons; Sensitivity and Specificity; Spectrum Analysis; X-Ray Diffraction | 2006 |
Occurrence of the leucine-to-phenylalanine knockdown resistance (kdr) mutation in Anopheles arabiensis populations in Tanzania, detected by a simplified high-throughput SSOP-ELISA method.
Topics: Animals; Anopheles; Enzyme-Linked Immunosorbent Assay; Female; Insecticide Resistance; Leucine; Mutation; Oligonucleotide Probes; Phenylalanine; Polymerase Chain Reaction; Pyrethrins; Sensitivity and Specificity; Tanzania | 2006 |
Role of the middle residue in the triple tryptophan electron transfer chain of DNA photolyase: ultrafast spectroscopy of a Trp-->Phe mutant.
Topics: Deoxyribodipyrimidine Photo-Lyase; Electron Transport; Escherichia coli; Flavin-Adenine Dinucleotide; Free Radicals; Mutation; Phenylalanine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tryptophan | 2006 |
Dehydrogenase based reagentless biosensor for monitoring phenylketonuria.
Topics: Amino Acid Oxidoreductases; Biosensing Techniques; Electrochemistry; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Humans; Indicators and Reagents; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity; Urinalysis | 2007 |
Application of an enzyme chip to the microquantification of l-phenylalanine.
Topics: Amino Acid Oxidoreductases; Blood Stains; Histidine; Humans; Infant, Newborn; Microchemistry; Neonatal Screening; Phenylalanine; Phenylketonurias; Protein Array Analysis; Reproducibility of Results; Sensitivity and Specificity | 2006 |
FRET analysis of protein conformational change through position-specific incorporation of fluorescent amino acids.
Topics: Calmodulin; Cell-Free System; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Phenylalanine; Protein Conformation; Sensitivity and Specificity; Spectrometry, Fluorescence; Structure-Activity Relationship | 2006 |
Assembly of hybrid synthetic capsules.
Topics: Calixarenes; Chloroform; Dimerization; Heterocyclic Compounds, 4 or More Rings; Hydrogen Bonding; Macrocyclic Compounds; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Phenylalanine; Reference Standards; Sensitivity and Specificity; Stereoisomerism | 2007 |
Supramolecular-mediated immobilization of L-phenylalanine dehydrogenase on cyclodextrin-coated Au electrodes for biosensor applications.
Topics: Amino Acid Oxidoreductases; Bacillus; beta-Cyclodextrins; Biosensing Techniques; Coated Materials, Biocompatible; Electrochemistry; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Gold; Microelectrodes; Multiprotein Complexes; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity | 2007 |
Quantitative determination of JAK2 V617F by TaqMan: An absolute measure of averaged copies per cell that may be associated with the different types of myeloproliferative disorders.
Topics: Amino Acid Substitution; Case-Control Studies; Gene Dosage; Humans; Janus Kinase 2; Myeloproliferative Disorders; Phenotype; Phenylalanine; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Valine | 2007 |
Amplification refractory mutation system, a highly sensitive and simple polymerase chain reaction assay, for the detection of JAK2 V617F mutation in chronic myeloproliferative disorders.
Topics: Chronic Disease; DNA Mutational Analysis; Exons; Genetic Testing; Genome, Human; Humans; Janus Kinase 2; Mutation; Myeloproliferative Disorders; Phenylalanine; Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity; Valine | 2007 |
Nateglinide quantification in rabbit plasma by HPLC: optimization and application to pharmacokinetic study.
Topics: Administration, Oral; Animals; Area Under Curve; Buffers; Calibration; Chromatography, High Pressure Liquid; Cold Temperature; Cyclohexanes; Drug Stability; Freezing; Half-Life; Hydrogen-Ion Concentration; Hypoglycemic Agents; Metabolic Clearance Rate; Molecular Structure; Nateglinide; Phenylalanine; Rabbits; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Time Factors | 2007 |
Population quantile-quantile plots for monitoring assay performance in newborn screening.
Topics: Calibration; Carnitine; DNA Mutational Analysis; Humans; Infant, Newborn; Mass Screening; Mass Spectrometry; Mutation; Neonatal Screening; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity; United Kingdom | 2007 |
Intra-individual comparison of the human biodistribution and dosimetry of the D and L isomers of 2-[123I]iodo-phenylalanine.
Topics: Adult; Humans; Isomerism; Male; Metabolic Clearance Rate; Organ Specificity; Phenylalanine; Radiopharmaceuticals; Sensitivity and Specificity; Structure-Activity Relationship; Tissue Distribution; Whole-Body Counting | 2007 |
Surface recognition and fluorescence sensing of histone by dansyl-appended cyclophane-based resorcinarene trimer.
Topics: Aza Compounds; Calixarenes; Dimerization; Ethers, Cyclic; Fluorescence; Histones; Macrocyclic Compounds; Models, Chemical; Molecular Conformation; Phenylalanine; Sensitivity and Specificity; Surface Properties; Time Factors | 2007 |
Characterization of white matter alterations in phenylketonuria by magnetic resonance relaxometry and diffusion tensor imaging.
Topics: Adult; Brain; Diffusion Magnetic Resonance Imaging; Female; Humans; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity | 2007 |
PCR assay for differentiating between Group I (proteolytic) and Group II (nonproteolytic) strains of Clostridium botulinum.
Topics: Botulism; Clostridium botulinum; Food Contamination; Food Microbiology; Humans; Phenylalanine; Phylogeny; Polymerase Chain Reaction; Sensitivity and Specificity; Species Specificity | 2008 |
Enzymatic-chemical preparation of quinoxaline derivatives from L-amino acids for gas chromatographic-mass spectrometric analyses.
Topics: Amino Acid Oxidoreductases; Amino Acids; Carbon Isotopes; Chromatography, Ion Exchange; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Isotope Labeling; Phenylalanine; Quinoxalines; Sensitivity and Specificity | 1995 |
Synthesis and characterization of a bioluminogenic substrate for alpha-chymotrypsin.
Topics: Chromatography, High Pressure Liquid; Chymotrypsin; Firefly Luciferin; Indicators and Reagents; Kinetics; Luminescent Measurements; Magnetic Resonance Spectroscopy; Phenylalanine; Sensitivity and Specificity; Substrate Specificity | 1994 |
Rapid diagnosis of maple syrup urine disease in blood spots from newborns by tandem mass spectrometry.
Topics: False Positive Reactions; Humans; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Mass Spectrometry; Neonatal Screening; Paper; Phenylalanine; Reference Values; Sensitivity and Specificity; Valine | 1995 |
Phenylketonuria screening with a fluorometric microplate assay.
Topics: Fluorometry; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity | 1994 |
Neonatal screening for phenylketonuria: evaluation of an automated enzymatic method.
Topics: Amino Acid Oxidoreductases; Autoanalysis; Chromatography, High Pressure Liquid; Cost-Benefit Analysis; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Pilot Projects; Reproducibility of Results; Sensitivity and Specificity | 1994 |
Multicomponent analysis for alkaline phosphatase isoenzyme determination by multiple linear regression.
Topics: Alkaline Phosphatase; Bone and Bones; Electrophoresis; Hot Temperature; Humans; Intestines; Isoenzymes; Levamisole; Liver; Phenylalanine; Placenta; Regression Analysis; Sensitivity and Specificity | 1994 |
Assay of the human liver citric acid cycle probe phenylacetylglutamine and of phenylacetate in plasma by gas chromatography-mass spectrometry.
Topics: Adult; Citric Acid Cycle; Evaluation Studies as Topic; Gas Chromatography-Mass Spectrometry; Glutamine; Humans; Liver; Molecular Probes; Phenylacetates; Phenylalanine; Sensitivity and Specificity | 1993 |
Tissue-nonspecific alkaline phosphatase participates in the establishment and growth of feather germs in embryonic chick skin cultures.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Animals; Base Sequence; Chick Embryo; Cloning, Molecular; DNA; Feathers; Homoarginine; Levamisole; Molecular Sequence Data; Organ Culture Techniques; Phenylalanine; RNA, Messenger; Sensitivity and Specificity; Sequence Homology, Amino Acid; Skin; Tetramisole | 1995 |
An automated enzymatic method on the Roche COBAS MIRA S for monitoring phenylalanine in dried blood spots of patients with phenylketonuria.
Topics: Amino Acid Oxidoreductases; Blood Chemical Analysis; Evaluation Studies as Topic; Humans; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity | 1996 |
Determination of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine in human plasma by solid-phase extraction and column-switching high-performance liquid chromatography with ultraviolet detection.
Topics: Chromatography, High Pressure Liquid; Cyclohexanes; Humans; Hypoglycemic Agents; Nateglinide; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity | 1996 |
Quantitation of L-amino acids by substrate recycling between an aminotransferase and a dehydrogenase: application to the determination of L-phenylalanine in human blood.
Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Bacillus; Cytosol; Humans; Indicators and Reagents; Kidney; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry; Transaminases | 1996 |
Trace analysis in chiral separation of selected amino enantiomers.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Fluorometry; Leucine; Perchlorates; Phenylalanine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism; Threonine | 1996 |
Time-resolved fluorescence. An approach in protein analysis.
Topics: Animals; Cattle; Humans; Models, Theoretical; Phenylalanine; Proteins; Sensitivity and Specificity; Serum Albumin; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors; Tryptophan; Tyrosine | 1996 |
Successful and unsuccessful approaches to imaging carcinoids: comparison of a radiolabelled tryptophan hydroxylase inhibitor with a tracer of biogenic amine uptake and storage, and a somatostatin analogue.
Topics: 3-Iodobenzylguanidine; Adult; Animals; Carcinoid Tumor; Dogs; Enzyme Inhibitors; Female; Humans; Indium Radioisotopes; Iodine Radioisotopes; Iodobenzenes; Mast-Cell Sarcoma; Mice; Middle Aged; Neoplasms, Experimental; Phenylalanine; Predictive Value of Tests; Radionuclide Imaging; Rats; Sensitivity and Specificity; Serotonin; Somatostatin; Tissue Distribution; Tryptophan Hydroxylase | 1996 |
Design of specific structures using alpha,beta-dehydro-phenylalanine residues: synthesis, crystal structure, and molecular conformation of Boc-L-Val-delta Phe-delta Phe-L-Val-delta Phe-delta Phe-L-Val-OCH3, a 3(10)-helical heptapeptide.
Topics: Crystallography, X-Ray; Hydrogen Bonding; Oligopeptides; Phenylalanine; Protein Conformation; Sensitivity and Specificity | 1997 |
A tryptophan-2-monooxygenase based amperometric biosensor for L-tryptophan determination: use of a competitive inhibitor as a tool for selectivity increase.
Topics: Biosensing Techniques; Mixed Function Oxygenases; Phenylalanine; Sensitivity and Specificity; Tryptophan | 1997 |
Microtiter plate assay for biopterin using cryopreserved Crithidia fasciculata.
Topics: Animals; Biological Assay; Biopterins; Crithidia fasciculata; Cryoprotective Agents; Humans; Molecular Structure; Phenylalanine; Phenylketonurias; Reference Values; Reproducibility of Results; Sensitivity and Specificity | 1997 |
Quantitation of 4-cyclohexyl-2-hydroxy-3-(3-methylsulfanyl-2- [2-[(morpholine-4-carbonyl)amino]-3-phenylpropionylamino]propi onylamino ) butyric acid isopropyl ester (CP-80,794), a renin inhibitor, and its hydrolytic cleavage metabolite 2-[(morpholine-4-c
Topics: Animals; Chromatography, High Pressure Liquid; Dipeptides; Dogs; Humans; Morpholines; Phenylalanine; Reference Standards; Renin; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 1997 |
Rhodopsins from three frog and toad species: sequences and functional comparisons.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Bufo bufo; Bufo marinus; DNA; Hot Temperature; Molecular Sequence Data; Phenylalanine; Polymerase Chain Reaction; Rana temporaria; Ranidae; Rhodopsin; RNA, Messenger; Sensitivity and Specificity; Sequence Analysis, DNA; Sequence Analysis, RNA; Species Specificity; Spectrum Analysis | 1998 |
Quantitative analytical methods for the determination of a new hypertension drug, CGS 25462, and its metabolites (CGS 25659 and CGS 24592) in human plasma by high-performance liquid chromatography.
Topics: Administration, Oral; Antihypertensive Agents; Biphenyl Compounds; Chromatography, High Pressure Liquid; Circadian Rhythm; Half-Life; Humans; Male; Organophosphonates; Phenylalanine; Prodrugs; Protease Inhibitors; Reproducibility of Results; Sensitivity and Specificity; Temperature; Time Factors | 1998 |
Accurate measurement of cholecystokinin in plasma.
Topics: Adult; Animals; Antibodies; Antibody Specificity; Cholecystokinin; Cross Reactions; Female; Gastrins; Guinea Pigs; Humans; Immunization; Intestinal Mucosa; Male; Mice; Peptide Fragments; Phenylalanine; Rabbits; Radioimmunoassay; Reproducibility of Results; Sensitivity and Specificity; Swine; Tyrosine | 1998 |
Assessment of the reliability of single blastomere analysis for preimplantation diagnosis of the delta F508 deletion causing cystic fibrosis in clinical practice.
Topics: Biopsy; Blastomeres; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Embryonic Development; Female; Gene Deletion; Genotype; Heterozygote; Humans; Phenylalanine; Polymerase Chain Reaction; Pregnancy; Prenatal Diagnosis; Sensitivity and Specificity | 1998 |
Sensitivity of electrospray-tandem mass spectrometry using the phenylalanine/tyrosine-ratio for differential diagnosis of hyperphenylalaninemia in neonates.
Topics: Diagnosis, Differential; Humans; Infant, Newborn; Mass Spectrometry; Phenylalanine; Phenylketonurias; Predictive Value of Tests; Reference Values; Sensitivity and Specificity; Tyrosine | 1999 |
Repair of potentially lethal damage by total and quiescent cells in solid tumors following a neutron capture reaction.
Topics: Animals; Borohydrides; Boron Compounds; Boron Neutron Capture Therapy; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Division; Cytochalasin B; DNA Damage; Dose-Response Relationship, Radiation; Female; Gamma Rays; Mice; Mice, Inbred C3H; Micronucleus Tests; Neoplasm Transplantation; Phenylalanine; Sensitivity and Specificity; Sulfhydryl Compounds; Tumor Cells, Cultured | 1999 |
Apparatus and method for interfacing capillary electrophoresis and chemiluminescence nitrogen detection for the analysis of nitrogen-containing compounds.
Topics: Aminosalicylic Acid; Electrophoresis, Capillary; Luminescent Measurements; Nitrogen; Phenylalanine; Sensitivity and Specificity | 2000 |
Enhancement of the specificity of an enzyme-based biosensor for L-tryptophan.
Topics: Biosensing Techniques; Electrochemistry; Enzymes, Immobilized; Escherichia coli; Kinetics; Phenylalanine; Pseudomonas; Recombinant Proteins; Sensitivity and Specificity; Tryptophan; Tryptophan Hydroxylase | 1999 |
Comparison of two different methods for measurement of phenylalanine in dried blood spots.
Topics: Amino Acid Oxidoreductases; Humans; Neonatal Screening; Phenylalanine; Phenylketonurias; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity | 2000 |
Use of the phenylalanine:tyrosine ratio to test newborns for phenylketonuria in a large public health screening programme.
Topics: California; Chromatography, High Pressure Liquid; Humans; Infant, Newborn; Laboratories; Neonatal Screening; Phenylalanine; Phenylketonurias; Pilot Projects; Reproducibility of Results; Sensitivity and Specificity; Tyrosine | 2000 |
Effect of mobile phase acidic additives on enantioselectivity for phenylalanine analogs.
Topics: Acids; Phenylalanine; Sensitivity and Specificity; Stereoisomerism | 2001 |
Polyester microchannel chip for electrophoresis--incorporation of a blue LED as light source.
Topics: Amino Acids; Electrophoresis; Equipment Design; Fiber Optic Technology; Fluorescence; Microchemistry; Optical Fibers; Phenylalanine; Polyesters; Sensitivity and Specificity; Valine | 2001 |
[Determination of total phenylalanine and galactose from a sample of dry blood on paper filter: its application on neonatal screening].
Topics: Blood Stains; Enzyme-Linked Immunosorbent Assay; Galactose; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Reference Values; Sensitivity and Specificity | 2002 |
Glutamine transaminase K and cysteine S-conjugate beta-lyase activity stains.
Topics: Animals; Cysteine; Electrophoresis, Polyacrylamide Gel; Kidney; Lyases; Methionine; Molecular Weight; Nitroblue Tetrazolium; Phenylalanine; Rats; Rats, Inbred Strains; Sensitivity and Specificity; Staining and Labeling; Transaminases | 1991 |
Newborn screening for hyperphenylalaninemia on day 5: is 240 mumol/liter the most appropriate cut-off level?
Topics: Germany, West; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Predictive Value of Tests; Prospective Studies; Sensitivity and Specificity; Time Factors | 1990 |
A new approach to the newborn screening for hyperphenylalaninemias: use of L-phenylalanine dehydrogenase and microtiter plates.
Topics: Amino Acid Oxidoreductases; Colorimetry; Humans; Infant, Newborn; Neonatal Screening; Paper; Phenylalanine; Phenylketonurias; Sensitivity and Specificity | 1990 |