Page last updated: 2024-08-07 15:40:12
Beta-lactamase
[no definition available]
Synonyms
EC 3.5.2.6;
Cephalosporinase
Research
Bioassay Publications (16)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 11 (68.75) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (25)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| phloretin | Enterobacter cloacae | IC50 | 496.0000 | 1 | 1 |
| 3-aminobenzeneboronic acid | Enterobacter cloacae | Ki | 7.3000 | 1 | 1 |
| tazobactam | Enterobacter cloacae | IC50 | 20.9436 | 16 | 16 |
| tazobactam | Enterobacter cloacae | Ki | 170.0000 | 1 | 1 |
| sulbactam | Enterobacter cloacae | IC50 | 29.5000 | 3 | 3 |
| (z)-5-(2'-hydroxybenzylidene)-2-thioxothiazolidin-4-one | Enterobacter cloacae | IC50 | 335.0000 | 1 | 1 |
| quercetin | Enterobacter cloacae | IC50 | 269.6667 | 3 | 3 |
| rutin | Enterobacter cloacae | IC50 | 500.0000 | 1 | 1 |
| clavulanic acid | Enterobacter cloacae | IC50 | 118.1000 | 2 | 2 |
| rottlerin | Enterobacter cloacae | IC50 | 119.0000 | 2 | 2 |
| avibactam | Enterobacter cloacae | IC50 | 0.1000 | 1 | 1 |
| avibactam | Enterobacter cloacae | Ki | 7.7000 | 1 | 1 |
| tazobactam sodium | Enterobacter cloacae | IC50 | 29.6477 | 3 | 3 |
| clavulanate potassium | Enterobacter cloacae | IC50 | 434.5000 | 2 | 2 |
| penicillin g sodium | Enterobacter cloacae | IC50 | 5.4000 | 2 | 2 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| cephaloridine | Enterobacter cloacae | Km | 375.0000 | 4 | 4 |
| penicillin g | Enterobacter cloacae | Km | 5.9250 | 4 | 4 |
| cephalothin | Enterobacter cloacae | Km | 9.0000 | 1 | 1 |
| congo red | Enterobacter cloacae | Concentration | 3.9000 | 1 | 1 |
| doripenem | Enterobacter cloacae | Km | 9.6000 | 1 | 1 |
| imipenem, anhydrous | Enterobacter cloacae | Km | 24.0000 | 1 | 1 |
| tazobactam | Enterobacter cloacae | Km | 300.0000 | 1 | 1 |
| meropenem | Enterobacter cloacae | Km | 9.8000 | 1 | 1 |
| cefepime | Enterobacter cloacae | Km | 237.6667 | 3 | 3 |
| ceftazidime | Enterobacter cloacae | Km | 29.8250 | 4 | 4 |
| nitrocefin | Enterobacter cloacae | Km | 56.0000 | 1 | 1 |
| avibactam | Enterobacter cloacae | K | 5.1000 | 1 | 1 |
| sodium cephalothin | Enterobacter cloacae | Km | 15.4000 | 1 | 1 |
| ceftobiprole | Enterobacter cloacae | Km | 15.8000 | 3 | 3 |