A dihydrofolate reductase that is encoded in the genome of yeast. [OMA:P07807, PRO:DNx]
EC 1.5.1.3
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| trimethoprim | Saccharomyces cerevisiae S288C | IC50 | 12.0000 | 1 | 1 |
| trimetrexate | Saccharomyces cerevisiae S288C | IC50 | 0.0420 | 1 | 1 |
| piritrexim | Saccharomyces cerevisiae S288C | IC50 | 0.0310 | 1 | 1 |