fluxapyroxad

Description

fluxapyroxad: carboxamide; succinate dehydrogenase inhibitor [MeSH]

fluxapyroxad : An aromatic amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of 3',4',5'-trifluorobiphenyl-2-amine. Used to control a number of cereal fungal pathogens including those belonging to the Ascomycetes, Basidiomycetes and Zygomycetes families. [CHeBI]

Cross-References

ID Source	ID
PubMed CID	16095400
SCHEMBL ID	167627
CHEBI ID	83113
MeSH ID	M000598194

Synonyms (35)

Synonym
n-(2-(3,4,5-trifluorophenyl)phenyl)-3-difluoromethyl-1-methylpyrazole-4-carboxamide
3-(difluoromethyl)-1-methyl-n-(3',4',5'-trifluoro[1,1'-biphenyl]-2-yl)-1h-pyrazole-4-carboxamide
n-(3',4',5'-trifluorobiphenyl-2-yl)-1-methyl-3-difluoromethyl-1h-pyrazole-4-carboxamide
n-(3',4',5'-trifluorobiphenyl-2-yl)-3-difluoromethyl-1-methyl-1h-pyrazole-4-carboxamide
3-(difluoromethyl)-1-methyl-n-(3',4',5'-trifluorobiphenyl-2-yl)-1h-pyrazole-4-carboxamide
3-(difluoromethyl)-1-methyl-n-(3',4',5'-trifluorobiphenyl-2-yl)pyrazole-4-carboxamide
fluxapyroxad
907204-31-3
fluxapyroxad [iso]
3-(difluoromethyl)-1-methyl-n-(3',4',5'-trifluoro(1,1'-biphenyl)-2-yl)-1h-pyrazole-4-carboxamide
unii-7u8p4nar2s
7u8p4nar2s ,
xemium
SCHEMBL167627
CHEBI:83113
DTXSID6058215
AKOS027322014
3-(difluoromethyl)-1-methyl-n-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide
fluxapyroxad, pestanal(r), analytical standard
fluxapyroxad 100 microg/ml in acetonitrile
Z1552164593
EX-A1676
3-(difluoromethyl)-1-methyl-n-(3',4',5'-trifluoro-[1,1'-biphenyl]-2-yl)-1h-pyrazole-4-carboxamide ,
AS-36599
Q15632875
mfcd22373628
3-(difluoromethyl)-1-methyl-n-(3',4',5'-trifluorobiphenyl-2-yl)-1h-pyrazole-4-carboxamide; xemium
3-(difluoromethyl)-1-methyl-n-(3 inverted exclamation marka,4 inverted exclamation marka,5 inverted exclamation marka-trifluorobiphenyl-2-yl)pyrazole-4-carboxamide
HY-135549
CS-0113442
1h-pyrazole-4-carboxamide, 3-(difluoromethyl)-1-methyl-n-(3',4',5'-trifluoro[1,1'-biphenyl]-2-yl)-
AC-36586
3-(difluoromethyl)-1-methyl-n-{3',4',5'-trifluoro-[1,1'-biphenyl]-2-yl}-1h-pyrazole-4-carboxamide
EN300-264529
1ST000820

Roles (2)

Role	Description
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of succinate dehydrogenase (quinone), EC 1.3.5.1.
antifungal agrochemical	Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.

Drug Classes (5)

Class	Description
aromatic amide	An amide in which the amide linkage is bonded directly to an aromatic system.
biphenyls	Benzenoid aromatic compounds containing two phenyl or substituted-phenyl groups which are joined together by a single bond.
pyrazoles
trifluorobenzene	Any member of the class of fluorobenzenes carrying three fluorine substituents at unspecified positions.
anilide fungicide	Any amide fungicide whose structure contains an anilide group.

Research

Studies (33)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	14 (42.42)	24.3611
2020's	19 (57.58)	2.80

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (3.03%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	32 (96.97%)	84.16%

Substance	Classes	Roles	Relationship Strength
pk 11195	aromatic amide; isoquinolines; monocarboxylic acid amide; monochlorobenzenes	antineoplastic agent	low
acebutolol	aromatic amide; ethanolamines; ether; monocarboxylic acid amide; propanolamine; secondary amino compound	anti-arrhythmia drug; antihypertensive agent; beta-adrenergic antagonist; sympathomimetic agent	low
acetochlor	aromatic amide; monocarboxylic acid amide; organochlorine compound	environmental contaminant; herbicide; xenobiotic	low
alachlor	aromatic amide; monocarboxylic acid amide; organochlorine compound	environmental contaminant; herbicide; xenobiotic	low
dan 2163	aromatic amide; aromatic amine; benzamides; pyrrolidines; sulfone	environmental contaminant; second generation antipsychotic; xenobiotic	low
arotinolol	aromatic amide; thiophenes		low
bupivacaine	aromatic amide; piperidinecarboxamide; tertiary amino compound		low
glipizide	aromatic amide; monocarboxylic acid amide; N-sulfonylurea; pyrazines	EC 2.7.1.33 (pantothenate kinase) inhibitor; hypoglycemic agent; insulin secretagogue	low
granisetron	aromatic amide; indazoles		low
ly 278584	aromatic amide; indazoles		low
metolachlor	aromatic amide; benzenes; ether; organochlorine compound		low
pyroxamide	aromatic amide		low
n-phenylformamide	aromatic amide; formamides		low
nithiamide	acetamides; aromatic amide		low
furothiazole	aromatic amide		low
iocetamic acid	aromatic amide		low
benomyl	aromatic amide; benzimidazole fungicide; benzimidazoles; benzimidazolylcarbamate fungicide; carbamate ester	acaricide; anthelminthic drug; antifungal agrochemical; microtubule-destabilising agent; tubulin modulator	low
butachlor	aromatic amide; organochlorine compound; tertiary carboxamide	environmental contaminant; herbicide; xenobiotic	low
ribavirin	1-ribosyltriazole; aromatic amide; monocarboxylic acid amide; primary carboxamide	anticoronaviral agent; antiinfective agent; antimetabolite; antiviral agent; EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor	low
iopronic acid	aromatic amide		low
furalaxyl	alanine derivative; aromatic amide; carboxamide; furans; methyl ester		low
closantel	aromatic amide; monocarboxylic acid amide; monochlorobenzenes; nitrile; organoiodine compound; phenols		low
metalaxyl	alanine derivative; aromatic amide; carboxamide; ether; methyl ester		low
metazachlor	aromatic amide; organochlorine compound; pyrazoles	environmental contaminant; herbicide; xenobiotic	low
benalaxyl	alanine derivative; aromatic amide; carboxamide; methyl ester		low
oxadixyl	anilide fungicide; aromatic amide; carbohydrazide; ether; oxazolidinone	agrochemical	low
ranolazine	aromatic amide; monocarboxylic acid amide; monomethoxybenzene; N-alkylpiperazine; secondary alcohol		low
atorvastatin	aromatic amide; dihydroxy monocarboxylic acid; monofluorobenzenes; pyrroles; statin (synthetic)	environmental contaminant; xenobiotic	low
1,2,4-triazole-3-carboxamide	aromatic amide; monocarboxylic acid amide; primary carboxamide; triazoles	drug metabolite; human urinary metabolite	low
isonixin	aromatic amide		low
thifluzamide	1,3-thiazoles; anilide fungicide; aromatic amide; aromatic ether; dibromobenzene; organofluorine compound	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	low
foe 5043	aromatic amide; monofluorobenzenes; thiadiazoles	environmental contaminant; herbicide; xenobiotic	low
5-acetylamino-6-amino-3-methyluracil	aromatic amide		low
dimethenamid	aromatic amide; ether; organochlorine compound; thiophenes		low
ribavirin 5'-diphosphate	1-ribosyltriazole; aromatic amide; monocarboxylic acid amide; primary carboxamide; ribose monophosphate	antiviral agent; drug metabolite; EC 1.1.1.205 (IMP dehydrogenase) inhibitor; human blood serum metabolite	low
phenazine-1-carboxamide	aromatic amide; monocarboxylic acid amide; phenazines		low
ribavirin 5'-triphosphate	1-ribosyltriazole; aromatic amide; monocarboxylic acid amide; primary carboxamide; ribose triphosphate	antiviral agent; drug metabolite; EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor; eukaryotic initiation factor 4F inhibitor; human blood serum metabolite	low
ribavirin 5'-diphosphate	1-ribosyltriazole; aromatic amide; monocarboxylic acid amide; primary carboxamide; ribose diphosphate	antiviral agent; drug metabolite	low
rufinamide	aromatic amide; heteroarene		low
cyclazosin	aromatic amide; aromatic ether; furans; monocarboxylic acid amide; quinazolines; quinoxaline derivative	adenosine A2A receptor antagonist	low
yh 439	aromatic amide; isopropyl ester; secondary carboxamide		low
allantoxanamide	aromatic amide; heteroarene		low
fr 122047	aromatic amide; thiazoles		low
dabigatran etexilate	aromatic amide; benzimidazoles; beta-alanine derivative; carboxamidine; carboxylic ester; pyridines	anticoagulant; EC 3.4.21.5 (thrombin) inhibitor; prodrug	low
n-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide	anilide fungicide; aromatic amide; dichlorobenzene; monocarboxylic acid amide; phenols	antifungal agrochemical; EC 1.14.13.72 (methylsterol monooxygenase) inhibitor; sterol biosynthesis inhibitor	low
dabigatran	aromatic amide; benzimidazoles; beta-alanine derivative; carboxamidine; pyridines	anticoagulant; EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor; EC 3.4.21.5 (thrombin) inhibitor	low
4-amino-N-(4-methoxyphenyl)-2-(methylthio)-5-thiazolecarboxamide	aromatic amide		low
N-(2,6-dibromo-4-methylphenyl)-3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxamide	aromatic amide		low
N-(2-phenylphenyl)-2-pyrazinecarboxamide	aromatic amide		low
y 27632	aromatic amide		low
2-chloro-N-(5-methyl-3-isoxazolyl)acetamide	aromatic amide		low
N-[3,5-dimethyl-1-(1-oxopropyl)-4-pyrazolyl]propanamide	aromatic amide		low
N-(3,5-dimethoxyphenyl)-2-thiophenecarboxamide	aromatic amide		low
N-[1-[(2-bromophenyl)methyl]-2-oxo-3-pyridinyl]butanamide	aromatic amide		low
4-amino-3-[(cyclohexylamino)-oxomethyl]-5-isothiazolecarboxylic acid ethyl ester	aromatic amide; thiazoles		low
2-[[2-[[4-(2-furanylmethyl)-5-(phenylmethyl)-1,2,4-triazol-3-yl]thio]-1-oxoethyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide	aromatic amide; thiophenes		low
2-[2-[[2-[(5-cyclopropyl-4-methyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]amino]-4-thiazolyl]acetic acid ethyl ester	aromatic amide		low
N-[3-[[2-furanyl(oxo)methyl]amino]phenyl]-1-isoquinolinecarboxamide	aromatic amide; furans		low
N-[2,5-diethoxy-4-[[2-(3-methoxyphenyl)-1-oxoethyl]amino]phenyl]-2-furancarboxamide	aromatic amide; furans		low
5-(4-fluorophenyl)-N-[2-(1-piperidinyl)phenyl]-4-oxazolecarboxamide	aromatic amide		low
2-[[4-(2-furanylmethyl)-5-methyl-1,2,4-triazol-3-yl]thio]-N-(4-methyl-2-thiazolyl)acetamide	aromatic amide		low
5-methyl-N-[4-(4-morpholinyl)phenyl]-2-pyrazinecarboxamide	aromatic amide		low
N-[4-[oxo-(2-pyridinylamino)methyl]phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-[2,5-dimethoxy-4-[[oxo(thiophen-2-yl)methyl]amino]phenyl]-2-furancarboxamide	aromatic amide; furans		low
2-methoxy-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)acetamide	aromatic amide		low
N-(5-methyl-1,3,4-thiadiazol-2-yl)-N-phenyl-2-pyrazinecarboxamide	aromatic amide		low
2-[[(4-methyl-5-thieno[3,2-b]pyrrolyl)-oxomethyl]amino]benzoic acid methyl ester	aromatic amide		low
N-[2-methoxy-4-[(2-methyl-1-oxopropyl)amino]phenyl]-2-furancarboxamide	aromatic amide; furans		low
4,5-dimethyl-2-[[oxo(thiophen-2-yl)methyl]amino]-3-thiophenecarboxylic acid ethyl ester	aromatic amide; thiophenes		low
N-[2-methyl-5-(3-methyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl]-3-pyridinecarboxamide	aromatic amide		low
N-[2-(cyclopentylamino)-2-oxoethyl]-N-(4-methoxyphenyl)-6-(1-piperidinyl)-3-pyridinecarboxamide	aromatic amide		low
N-[2-methoxy-4-[[2-[(3-methyl-4-oxo-2-quinazolinyl)thio]-1-oxoethyl]amino]phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-propyl-N-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)-2-thiophenecarboxamide	aromatic amide; thiophenes		low
N-[2-[2-[2-(4-methoxyanilino)-2-oxoethyl]-5-tetrazolyl]phenyl]-2-furancarboxamide	aromatic amide; furans		low
9-oxo-N-(3-pyridinylmethyl)-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinoline-8-carboxamide	aromatic amide; quinolines		low
4-amino-N5-[1-(2-furanyl)-2-(3-methylbutylamino)-2-oxoethyl]-N5-(2-methoxyphenyl)isothiazole-3,5-dicarboxamide	aromatic amide		low
N-[4-(4-acetyl-1-piperazinyl)phenyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide	aromatic amide		low
N-[3-chloro-4-(4-morpholinyl)phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-[[5-(2-methyl-3-furanyl)-4-(2-methylpropyl)-1,2,4-triazol-3-yl]thio]acetamide	aromatic amide		low
5-(2-furanyl)-N-(4-methylphenyl)-3-isoxazolecarboxamide	aromatic amide		low
N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-3,3,3-trifluoro-2-methyl-2-(trifluoromethyl)propanamide	aromatic amide		low
4-amino-N-(2-oxolanylmethyl)-3-prop-2-enyl-2-sulfanylidene-5-thiazolecarboxamide	aromatic amide; thiazoles		low
3-amino-5-methyl-4-[[3-(4-morpholinyl)propylamino]-oxomethyl]-2-thiophenecarboxylic acid ethyl ester	aromatic amide; thiophenes		low
N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2,2-bis(trifluoromethyl)butanamide	aromatic amide		low
N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-phenyl-2-furancarboxamide	aromatic amide; furans		low
N-[5-[2-(4-morpholinyl)ethyl]-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide	aromatic amide		low
N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-2-furancarboxamide	aromatic amide; heteroarene		low
5-(3-chlorophenyl)-N-[2-methyl-5-(3-methyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl]-2-furancarboxamide	aromatic amide; furans		low
4-amino-3-methyl-N-(phenylmethyl)-2-sulfanylidene-5-thiazolecarboxamide	aromatic amide; thiazoles		low
N-[4-(diethylamino)phenyl]-2-furancarboxamide	aromatic amide; furans		low
3-[[2-benzofuranyl(oxo)methyl]amino]benzoic acid ethyl ester	aromatic amide; furans		low
N-(4-fluorophenyl)-2,1,3-benzothiadiazole-5-carboxamide	aromatic amide		low
N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-2-thiophen-2-ylacetamide	aromatic amide		low
N-(3-pyridinyl)-2,3-dihydrothieno[3,4-b][1,4]dioxin-5-carboxamide	aromatic amide; thiophenes		low
2-[[2,3-dihydro-1,4-benzodioxin-6-yl(oxo)methyl]amino]benzoic acid methyl ester	aromatic amide		low
5-(2,4-dichlorophenyl)-N-(2-methylphenyl)-2-furancarboxamide	aromatic amide; furans		low
4-[[2-furanyl(oxo)methyl]amino]benzoic acid propan-2-yl ester	aromatic amide; furans; isopropyl ester; secondary carboxamide		low
N-(2,5-dimethylphenyl)-2-benzofurancarboxamide	aromatic amide; furans		low
N-(4-methoxyphenyl)-2-benzofurancarboxamide	aromatic amide; furans		low
1-cyclohexyl-3-[[oxo(thiophen-2-yl)methyl]amino]thiourea	aromatic amide; thiophenes		low
N-[4-(3,4-dimethylphenyl)-2-thiazolyl]-2-furancarboxamide	aromatic amide; heteroarene		low
Methyl 3-(isonicotinoylamino)-4-methylbenzoate	aromatic amide		low
N-[[(5-chloro-2-pyridinyl)amino]-sulfanylidenemethyl]-2-thiophenecarboxamide	aromatic amide; thiophenes		low
N-phenethyl-2-furamide	aromatic amide; heteroarene		low
4-[[oxo(thiophen-2-yl)methyl]amino]benzoic acid	aromatic amide		low
N-(2,6-dimethoxy-4-pyrimidinyl)-3-phenylpropanamide	aromatic amide		low
N-(4-ethylphenyl)-4-oxo-3H-phthalazine-1-carboxamide	aromatic amide		low
N-(2-tert-butyl-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl)-2-thiophenecarboxamide	aromatic amide; thiophenes		low
N-[4-[oxo(1-piperidinyl)methyl]phenyl]-2-thiophenecarboxamide	aromatic amide		low
5-bromo-N-(2,4-dichlorophenyl)-2-furancarboxamide	aromatic amide; furans		low
N-[3-chloro-4-(1-pyrrolidinyl)phenyl]-2-furancarboxamide	aromatic amide; furans		low
2-hydroxy-5-[[(5-methyl-2-furanyl)-oxomethyl]amino]benzoic acid	aromatic amide; furans		low
N-[3-[[2-furanyl(oxo)methyl]amino]phenyl]-5-nitro-2-furancarboxamide	aromatic amide; furans		low
4-cyano-3-methyl-5-(4-methylphenyl)-2-thiophenecarbohydrazide	aromatic amide; thiophenes		low
3-[[(2,5-dimethyl-3-furanyl)-oxomethyl]amino]benzoic acid	aromatic amide; furans		low
4-methyl-N-(3-nitrophenyl)-5-phenyl-3-thiophenecarboxamide	aromatic amide		low
5-bromo-N-(4-propan-2-ylphenyl)-2-furancarboxamide	aromatic amide; furans		low
N-(cyclopentylideneamino)-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide	aromatic amide; pyrazoles		low
N,4-dimethyl-5-phenyl-2-thiophenecarboxamide	aromatic amide; thiophenes		low
5-[anilino(oxo)methyl]-4-methyl-2-(1-oxopropylamino)-3-thiophenecarboxylic acid methyl ester	aromatic amide		low
4-methyl-N,5-diphenyl-3-thiophenecarboxamide	aromatic amide		low
N-(2-pyridinyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide	aromatic amide; thiophenes		low
N-(4-bromo-2-fluorophenyl)-2-methyl-3-furancarboxamide	aromatic amide; furans		low
N-(3-chlorophenyl)-1-ethyl-5-methyl-4-pyrazolecarboxamide	aromatic amide		low
N-[5-(methylthio)-1,3,4-thiadiazol-2-yl]-3-phenylpropanamide	aromatic amide		low
4-phenyl-N-(2-pyridinyl)butanamide	aromatic amide		low
2-[[(5-bromo-2-furanyl)-oxomethyl]amino]benzoic acid	aromatic amide; furans		low
N-(4-fluoro-3-nitrophenyl)-3-methyl-2-thiophenecarboxamide	aromatic amide		low
N-[1-[(4-fluorophenyl)methyl]-3-pyrazolyl]-5-methyl-2-furancarboxamide	aromatic amide; heteroarene		low
N-(3-carbamoyl-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-4-chloro-2-methyl-3-pyrazolecarboxamide	aromatic amide; thiophenes		low
N-(4,5-dihydrothiazol-2-yl)-1-ethyl-3-pyrazolecarboxamide	aromatic amide; pyrazoles		low
N-(2-bromo-4-methylphenyl)-5-ethyl-3-thiophenecarboxamide	aromatic amide		low
1-[[(1,3-dimethyl-4-pyrazolyl)-oxomethyl]amino]-3-(4-methylphenyl)thiourea	aromatic amide; pyrazoles		low
2,5-dimethyl-4-nitro-N-[4-(1-pyrazolylmethyl)phenyl]-3-pyrazolecarboxamide	aromatic amide		low
1-(2-methylphenyl)-3-[[(5-methyl-3-thiophenyl)-oxomethyl]amino]thiourea	aromatic amide; thiophenes		low
1-(3-methylphenyl)-3-[[(5-methyl-3-thiophenyl)-oxomethyl]amino]thiourea	aromatic amide; thiophenes		low
1-(3-methylphenyl)-3-[[oxo-(5-propyl-3-thiophenyl)methyl]amino]thiourea	aromatic amide; thiophenes		low
N-(2-chlorophenyl)-5-nitro-2-furancarboxamide	aromatic amide; furans		low
4-chloro-N-[2-fluoro-5-(trifluoromethyl)phenyl]-2-methyl-3-pyrazolecarboxamide	aromatic amide		low
5-methyl-N-(5-methyl-3-isoxazolyl)-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
N-[4-(5-bromo-2-thiophenyl)-2-thiazolyl]acetamide	acetamides; aromatic amide		low
N-(4-methoxyphenyl)-2-(2-methylpropyl)-4-quinolinecarboxamide	aromatic amide		low
N-(2-chlorophenyl)-2-[[cyclopropyl(oxo)methyl]amino]-4-methyl-5-thiazolecarboxamide	aromatic amide		low
5-methyl-N-(3-pyridinyl)-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
2-[[oxo(thiophen-2-yl)methyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid propan-2-yl ester	aromatic amide; isopropyl ester; secondary carboxamide; thiophenes		low
N-(3-hydroxyphenyl)-5-methyl-3-furancarboxamide	aromatic amide; furans		low
5-(4-chlorophenyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-furancarboxamide	aromatic amide; heteroarene		low
N-(5-fluoro-2-methylphenyl)-1,3-benzodioxole-5-carboxamide	aromatic amide		low
N-(2-cyano-1-cyclopentenyl)-1-ethyl-3-pyrazolecarboxamide	aromatic amide; heteroarene		low
N-[4-[[acetamido(sulfanylidene)methyl]amino]phenyl]-2-thiophenecarboxamide	aromatic amide		low
N-[3-[(1,3-dioxo-5-isoindolyl)oxy]phenyl]-2-furancarboxamide	aromatic amide; furans		low
2-methyl-N-(2,4,6-trimethylphenyl)-3-furancarboxamide	aromatic amide; furans		low
4-[[(2-methyl-1,3-benzothiazol-6-yl)-oxomethyl]amino]benzoic acid methyl ester	aromatic amide		low
N-(4-ethoxyphenyl)-1,2,5-thiadiazole-3-carboxamide	aromatic amide		low
4-bromo-1-methyl-N-(2-thiazolyl)-3-pyrazolecarboxamide	aromatic amide; heteroarene		low
N-(3-methoxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide	aromatic amide		low
3-[[(5-bromo-2-furanyl)-oxomethyl]amino]-2-methylbenzoic acid	aromatic amide; furans		low
5-phenyl-N-(3-pyridinyl)-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
(5-phenyl-3-isoxazolyl)-(1-pyrrolidinyl)methanone	aromatic amide; heteroarene		low
N-(2-pyridinyl)-2-[[5-(3-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]acetamide	aromatic amide		low
4-[oxo-(pyridin-4-ylamino)methyl]-1H-imidazole-5-carboxylic acid ethyl ester	aromatic amide; heteroarene		low
N-(2-hydroxy-5-methylphenyl)-1,3-dioxo-2-propyl-5-isoindolecarboxamide	aromatic amide		low
N-[3-[oxo-(3-pyridinylmethylamino)methyl]phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-[(1-ethyl-2-oxo-6-benzo[cd]indolyl)sulfonyl]-N-(4-methoxyphenyl)-3-pyridinecarboxamide	aromatic amide		low
5-chloro-N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-3-methyl-2-benzofurancarboxamide	aromatic amide; furans		low
3-amino-2-[(4-methoxyanilino)-oxomethyl]-4-(4-methoxyphenyl)-6-methyl-5-thieno[2,3-b]pyridinecarboxylic acid ethyl ester	aromatic amide		low
2-[[4-(2-furanyl)-6-(trifluoromethyl)-2-pyrimidinyl]thio]-N-(5-methyl-3-isoxazolyl)acetamide	aromatic amide		low
N-(4-methoxyphenyl)-N-thiophen-2-ylsulfonyl-2-furancarboxamide	aromatic amide; furans		low
5-[(2,4-dichlorophenoxy)methyl]-N-(2-fluorophenyl)-2-furancarboxamide	aromatic amide; furans		low
2-[(3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio]-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)acetamide	aromatic amide		low
3-amino-N-(2-fluorophenyl)-6-(phenylmethyl)-4-(trifluoromethyl)-2-thieno[2,3-b]pyridinecarboxamide	aromatic amide		low
5-(4-bromophenyl)-N-(2-methoxyphenyl)-2-furancarboxamide	aromatic amide; furans		low
5-bromo-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-[3-chloro-2-(4-morpholinyl)phenyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide	aromatic amide		low
N-[3-[oxo-(3-pyridinylmethylamino)methyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-2-furancarboxamide	aromatic amide; thiophenes		low
N-(4-chlorophenyl)-7,8-dimethoxy-1-oxo-2-benzothiopyran-3-carboxamide	aromatic amide		low
N-(2-methoxyphenyl)-5-methyl-3-[(2-methylphenyl)methyl]-4-oxo-6-thieno[2,3-d]pyrimidinecarboxamide	aromatic amide		low
2-[acetyl(2-furanylmethyl)amino]-N-(4-chlorophenyl)-5-methyl-4-thiazolecarboxamide	aromatic amide		low
N-[2-[2-[2-(4-ethoxyanilino)-2-oxoethyl]-5-tetrazolyl]phenyl]-2-thiophenecarboxamide	aromatic amide		low
N-(3-methylphenyl)-4-(4-nitrophenyl)-2-phenyl-5-thiazolecarboxamide	aromatic amide		low
N-(5-chloro-2-pyridinyl)-2-ethyl-3-pyrazolecarboxamide	aromatic amide; heteroarene		low
5-amino-4-[anilino(oxo)methyl]-3-methyl-2-thiophenecarboxylic acid ethyl ester	aromatic amide		low
5-(3-chlorophenyl)-N-(2-propyl-5-tetrazolyl)-2-furancarboxamide	aromatic amide; heteroarene		low
N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-2-thiophenecarboxamide	aromatic amide; thiophenes		low
N-[5-(1,3-benzothiazol-2-yl)-2-chlorophenyl]-1,3-benzodioxole-5-carboxamide	aromatic amide		low
N-[4-[[2-furanyl(oxo)methyl]amino]phenyl]-1,3-benzodioxole-5-carboxamide	aromatic amide; furans		low
5-(4-methylphenyl)-N-(3-pyridinylmethyl)-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
N-(4-cyano-2-methyl-3-pyrazolyl)-5-(4-methylphenyl)-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
N-(6-methyl-2-pyridinyl)-2-(phenylmethyl)sulfonylacetamide	aromatic amide		low
5-nitro-N-[4-(2-oxazolo[4,5-b]pyridinyl)phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-[4-[[2-(4-hydroxyphenyl)-1,3-dioxo-5-isoindolyl]oxy]phenyl]-2-thiophenecarboxamide	aromatic amide		low
2-furanyl-(4,4,8-trimethyl-1-sulfanylidene-5-dithiolo[3,4-c]quinolinyl)methanone	aromatic amide; heteroarene		low
3-(2-chloro-6-fluorophenyl)-N-(3-fluoro-4-methylphenyl)-5-methyl-4-isoxazolecarboxamide	aromatic amide		low
N-[4-[[[[oxo(thiophen-2-yl)methyl]amino]-sulfanylidenemethyl]amino]phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-[3-chloro-4-[[2-furanyl(oxo)methyl]amino]phenyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide	aromatic amide; furans		low
2-methyl-N-(3-methylphenyl)-3-imidazo[1,2-a]pyridinecarboxamide	aromatic amide		low
N-[2,5-diethoxy-4-[[(2-methylpropylamino)-sulfanylidenemethyl]amino]phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-[2,5-diethoxy-4-[[ethylamino(sulfanylidene)methyl]amino]phenyl]-2-thiophenecarboxamide	aromatic amide		low
N-[2,5-diethoxy-4-[[(2-furanylmethylamino)-sulfanylidenemethyl]amino]phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-(4-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide	aromatic amide		low
N2,N5-bis(3-acetamidophenyl)pyridine-2,5-dicarboxamide	aromatic amide		low
4-chloro-1-methyl-N-[1-[(4-methylphenyl)methyl]-3-pyrazolyl]-3-pyrazolecarboxamide	aromatic amide; heteroarene		low
N-(5-chloro-2-pyridinyl)-2-(3,5-dimethyl-4-nitro-1-pyrazolyl)acetamide	aromatic amide		low
N-[4-[methyl(phenyl)sulfamoyl]phenyl]-2-thiophenecarboxamide	aromatic amide		low
3-[[(2-cyclohexyl-1,3-dioxo-5-isoindolyl)-oxomethyl]amino]benzoic acid	aromatic amide		low
2-[(3-cyano-6-methyl-2-pyridinyl)thio]-N-(2-thiazolyl)acetamide	aromatic amide		low
N-(benzenesulfonyl)-N-(4-methoxyphenyl)-3-pyridinecarboxamide	aromatic amide		low
5-bromo-N-[3-chloro-2-(1-pyrrolidinyl)phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-[(2-fluorophenyl)methyl]-2-thiophenecarboxamide	aromatic amide; thiophenes		low
N-(3-carbamoyl-5-propyl-2-thiophenyl)-2-methyl-3-furancarboxamide	aromatic amide; thiophenes		low
N-(2-carbamoylphenyl)-4-ethyl-5-methyl-3-thiophenecarboxamide	aromatic amide		low
5-methyl-N-[2-(methylthio)phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-(2-furanylmethyl)-5-methyl-4-phenyl-3-thiophenecarboxamide	aromatic amide; thiophenes		low
5-methyl-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
4-ethyl-5-methyl-N-[1-[(3-methylphenyl)methyl]-1,2,4-triazol-3-yl]-3-thiophenecarboxamide	aromatic amide; thiophenes		low
5-bromo-N-[2-(4-chlorophenyl)ethyl]-2-thiophenecarboxamide	aromatic amide; thiophenes		low
5-bromo-N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-2-thiophenecarboxamide	aromatic amide; thiophenes		low
2-acetamido-5-propyl-3-thiophenecarboxamide	acetamides; aromatic amide		low
N-(5-tert-butyl-2-methoxyphenyl)-3,5-dimethyl-4-isoxazolecarboxamide	aromatic amide		low
N-[1-[(4-chlorophenyl)methyl]-4-pyrazolyl]cyclopentanecarboxamide	aromatic amide		low
3,5-dimethyl-N-[2-(methylthio)phenyl]-4-isoxazolecarboxamide	aromatic amide		low
N-[2-(4-fluorophenyl)ethyl]-5-methyl-2-thiophenecarboxamide	aromatic amide; thiophenes		low
N-(3-hydroxyphenyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamide	aromatic amide		low
propanoic acid [4-[[2-furanyl(oxo)methyl]amino]phenyl] ester	aromatic amide; furans		low
N-[4-[4-(1-oxopropyl)-1-piperazinyl]phenyl]-2-furancarboxamide	aromatic amide; furans		low
8-chloro-N-(4-fluorophenyl)-2-(2-pyridinyl)-4-quinolinecarboxamide	aromatic amide		low
N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-6,8-dimethyl-2-(3-pyridinyl)-4-quinolinecarboxamide	aromatic amide		low
N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-6,8-dimethyl-2-(2-pyridinyl)-4-quinolinecarboxamide	aromatic amide		low
6,8-dimethyl-N-[4-[(5-methyl-3-isoxazolyl)sulfamoyl]phenyl]-2-(2-pyridinyl)-4-quinolinecarboxamide	aromatic amide		low
N-(4-methyl-2-thiazolyl)-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)thio]acetamide	aromatic amide		low
2-[[5-(3-fluorophenyl)-1,3,4-oxadiazol-2-yl]thio]-N-(1,3,4-thiadiazol-2-yl)acetamide	aromatic amide		low
N-[2-[4-[(4-chlorophenyl)-oxomethyl]-1-piperazinyl]phenyl]-1,3-benzodioxole-5-carboxamide	aromatic amide		low
4-[[(4-bromo-2-ethyl-3-pyrazolyl)-oxomethyl]amino]benzoic acid propan-2-yl ester	aromatic amide; isopropyl ester; secondary carboxamide		low
N-[4-[[[[(4-tert-butylphenyl)-oxomethyl]amino]-sulfanylidenemethyl]amino]-2-methoxyphenyl]-2-thiophenecarboxamide	aromatic amide		low
3-(2-chlorophenyl)-5-methyl-N-[4-[2-(4-morpholinyl)-2-oxoethoxy]phenyl]-4-isoxazolecarboxamide	aromatic amide		low
5-[(cyclohexylamino)-oxomethyl]-4-methyl-2-[(1-oxo-2-thiophen-2-ylethyl)amino]-3-thiophenecarboxylic acid ethyl ester	aromatic amide; thiophenes		low
N-[3-[[2-(2-bromo-4,6-dimethylphenoxy)-1-oxoethyl]amino]phenyl]-2-furancarboxamide	aromatic amide; furans		low
5-(2-chlorophenyl)-N-phenyl-2-furancarboxamide	aromatic amide; furans		low
N-[4-(4-morpholinyl)phenyl]-5-(2-nitrophenyl)-2-furancarboxamide	aromatic amide; furans		low
5-[(3-aminoanilino)-oxomethyl]-4-methyl-2-(1-oxobutylamino)-3-thiophenecarboxylic acid methyl ester	aromatic amide		low
3-amino-8-methyl-N-[4-(4-morpholinyl)phenyl]-2-thieno[2,3-b]quinolinecarboxamide	aromatic amide		low
N-[5-[(2,2-dimethyl-1-oxopropyl)amino]-2-pyridinyl]-2-furancarboxamide	aromatic amide		low
5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2,5-dimethylphenyl)-3-methyl-2-furancarboxamide	aromatic amide; furans		low
4-methyl-2-[(1-oxo-2-phenoxyethyl)amino]-N-phenyl-5-thiazolecarboxamide	aromatic amide		low
N-(4-bromophenyl)-1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-pyrrolecarboxamide	aromatic amide		low
[[[3-[(4-methylphenyl)methoxy]-2-thiophenyl]-oxomethyl]amino]thiourea	aromatic amide; thiophenes		low
N,5-bis(4-methoxyphenyl)-2-thiophenecarboxamide	aromatic amide		low
1-(6-methyl-2-pyridinyl)-N-(3-pyridinyl)-4-imidazolecarboxamide	aromatic amide; heteroarene		low
5-(4-chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamide	aromatic amide; furans		low
4-chloro-N-(3,4-dimethoxyphenyl)-1-ethyl-3-pyrazolecarboxamide	aromatic amide		low
N-(4-fluorophenyl)-3H-benzimidazole-5-carboxamide	aromatic amide		low
2-[2-[[1-oxo-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)thio]ethyl]amino]-4-thiazolyl]acetic acid ethyl ester	aromatic amide		low
N-[4-[[(1-oxohexylamino)-sulfanylidenemethyl]amino]phenyl]-2-furancarboxamide	aromatic amide; furans		low
5-[diethylamino(oxo)methyl]-4-methyl-2-(1-oxopentylamino)-3-thiophenecarboxylic acid methyl ester	aromatic amide; thiophenes		low
5-bromo-N-[[[oxo(thiophen-2-yl)methyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamide	aromatic amide; thiophenes		low
N-[5-(ethoxymethyl)-1,3,4-thiadiazol-2-yl]-2-(phenylthio)acetamide	aromatic amide		low
5-bromo-N-(2-fluorophenyl)-6-oxo-3-pyrancarboxamide	aromatic amide		low
4-[[3-[(2-methoxyanilino)-oxomethyl]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl]amino]-4-oxobutanoic acid	aromatic amide		low
3-amino-N-(2-fluorophenyl)-6-(2-furanyl)-2-thieno[2,3-b]pyridinecarboxamide	aromatic amide		low
3-amino-N-(2-fluorophenyl)-6-(3-pyridinyl)-2-thieno[2,3-b]pyridinecarboxamide	aromatic amide		low
LSM-20401	aromatic amide		low
N-(4-bromophenyl)-5-tert-butyl-2-methyl-4-nitro-3-pyrazolecarboxamide	aromatic amide		low
1-[(2-chlorophenyl)methyl]-3-methyl-N-(4-methyl-2-thiazolyl)-5-thieno[2,3-c]pyrazolecarboxamide	aromatic amide; thiophenes		low
2-[[2-furanyl(oxo)methyl]amino]benzoic acid [2-(cyclohexylmethylamino)-2-oxoethyl] ester	aromatic amide; furans		low
2-[2-[[2-[(3-carbamoyl-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)amino]-2-oxoethyl]thio]-4-thiazolyl]acetic acid ethyl ester	aromatic amide; thiophenes		low
5-bromo-N-[2-(4-morpholinyl)-5-(trifluoromethyl)phenyl]-3-pyridinecarboxamide	aromatic amide		low
2-[[2-[5-(4-morpholinylsulfonyl)-2-thiophenyl]-1-oxoethyl]amino]-5-phenyl-3-thiophenecarboxamide	aromatic amide; thiophenes		low
4-[[oxo-(1-phenyl-3-pyridin-4-yl-4-pyrazolyl)methyl]amino]benzoic acid methyl ester	aromatic amide		low
N-(4-acetylphenyl)-5-[(phenylthio)methyl]-2-furancarboxamide	aromatic amide; furans		low
N-(4-methoxyphenyl)-5-(phenoxymethyl)-2-furancarboxamide	aromatic amide; furans		low
3-cyclohexyl-N-(1,3-dimethyl-2,6-dioxo-4-pyrimidinyl)propanamide	aromatic amide		low
4-[[(2-methyl-3-furanyl)-oxomethyl]amino]benzoic acid butyl ester	aromatic amide; furans		low
4-[[[5-[(4-chloro-3,5-dimethyl-1-pyrazolyl)methyl]-2-furanyl]-oxomethyl]amino]benzoic acid propan-2-yl ester	aromatic amide; furans; isopropyl ester		low
2-methyl-N-(2,3,4,5,6-pentafluorophenyl)-3-furancarboxamide	aromatic amide; furans		low
N-[2,2-dimethyl-3-[[oxo(thiophen-2-yl)methyl]amino]propyl]-2-thiophenecarboxamide	aromatic amide; thiophenes		low
5-bromo-N-(2-phenylphenyl)-2-furancarboxamide	aromatic amide; furans		low
N-(2-methoxyphenyl)-5-methyl-3-(1-naphthalenylmethyl)-4-oxo-6-thieno[2,3-d]pyrimidinecarboxamide	aromatic amide		low
N-[2-[4-[(4-chlorophenyl)-oxomethyl]-1-piperazinyl]phenyl]-2-benzofurancarboxamide	aromatic amide; furans		low
N-[5-(3-methoxyphenyl)-1,3,4-thiadiazol-2-yl]-2-thiophenecarboxamide	aromatic amide; thiophenes		low
1-[[(4-ethyl-5-methyl-3-thiophenyl)-oxomethyl]amino]-3-(2-phenylethyl)thiourea	aromatic amide; thiophenes		low
2,3-bis(2-furanyl)-N-[4-(4-morpholinyl)phenyl]-6-quinoxalinecarboxamide	aromatic amide		low
6-bromo-2-(3-pyridinyl)-N-[4-(trifluoromethyl)phenyl]-4-quinolinecarboxamide	aromatic amide		low
4-[[oxo-[2-(2-pyridinyl)-4-quinolinyl]methyl]amino]benzoic acid methyl ester	aromatic amide		low
N-[3-[[2-(2,6-dimethylphenoxy)-1-oxoethyl]amino]phenyl]-2-furancarboxamide	aromatic amide; furans		low
5-bromo-N-[2-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-[2-(1-cyclohexenyl)ethyl]-5-methyl-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
N-[3-[(cyclopropylamino)-oxomethyl]-4,5,6,7,8,9-hexahydrocycloocta[b]thiophen-2-yl]-2-furancarboxamide	aromatic amide; thiophenes		low
2-[[(2-methyl-3-furanyl)-oxomethyl]amino]benzoic acid	aromatic amide; furans		low
N-(3-acetylphenyl)-5,7-dimethyl-2-pyrazolo[1,5-a]pyrimidinecarboxamide	aromatic amide		low
[3,5-bis[(phenylmethyl)amino]-1,2,4-triazol-1-yl]-thiophen-2-ylmethanone	aromatic amide; thiophenes		low
2-[[[5-(3-chlorophenyl)-2-furanyl]-oxomethyl]amino]benzoic acid methyl ester	aromatic amide; furans		low
N-[4-(4-morpholinyl)phenyl]-2-pyridin-4-yl-4-quinolinecarboxamide	aromatic amide		low
5-chloro-N-(3,4-dimethylphenyl)-2,1-benzothiazole-3-carboxamide	aromatic amide		low
[[2-[[4-(4-bromophenyl)-2-thiazolyl]amino]-2-oxoethyl]thio]methanethioic acid O-ethyl ester	aromatic amide		low
N-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)-2-furancarboxamide	aromatic amide; heteroarene		low
5-methyl-N-(4-propan-2-ylphenyl)-2-pyrazinecarboxamide	aromatic amide		low
2-pyridin-4-yl-N-[4-(2-thiazolylsulfamoyl)phenyl]-4-quinolinecarboxamide	aromatic amide		low
N-[4-(1-piperidinyl)phenyl]-2-quinolinecarboxamide	aromatic amide		low
2,5-dimethyl-1-(3-methylphenyl)-N-(4-methylphenyl)-3-pyrrolecarboxamide	aromatic amide		low
N-[4-(difluoromethylthio)phenyl]-5-[(2-hydroxy-5-methoxyphenyl)-oxomethyl]-2-imino-3-pyrancarboxamide	aromatic amide		low
N-(2-tert-butylphenyl)-2,2-dioxo-3,4-dihydro-[1,2,4]thiadiazino[3,4-b][1,3]benzothiazole-8-carboxamide	aromatic amide		low
N-(4-tert-butyl-2-thiazolyl)-5-methyl-2-thiophenecarboxamide	aromatic amide; thiophenes		low
2-[[2-furanyl(oxo)methyl]amino]-4,5-dimethoxybenzoic acid [2-[(3,5-dichloro-2-pyridinyl)amino]-2-oxoethyl] ester	aromatic amide; furans		low
4-acetyl-N-[4-(4-chlorophenyl)-2-thiazolyl]-3,5-dimethyl-1H-pyrrole-2-carboxamide	aromatic amide; heteroarene		low
N-(6-methoxy-3-pyridinyl)-3-methyl-2-thiophenecarboxamide	aromatic amide; thiophenes		low
N-(4-chloro-2-fluorophenyl)-3-(methoxymethyl)-2-benzofurancarboxamide	aromatic amide; furans		low
7-methyl-N-[4-(4-morpholinyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide	aromatic amide		low
N-[4-(2-pyridinyl)-2-thiazolyl]cyclopentanecarboxamide	aromatic amide		low
5-[2-[[2-[[2-furanyl(oxo)methyl]amino]phenyl]-oxomethoxy]-1-oxoethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester	aromatic amide; furans		low
N-[2-[(1,3-benzodioxol-5-ylmethylamino)-oxomethyl]phenyl]-2-ethoxy-3-pyridinecarboxamide	aromatic amide		low
N-(5-methyl-2-thiazolyl)cyclopentanecarboxamide	aromatic amide		low
2-[[2-[[5-(4-ethylanilino)-1,3,4-thiadiazol-2-yl]thio]-1-oxoethyl]amino]-3-thiophenecarboxamide	aromatic amide; thiophenes		low
N-(4-chlorophenyl)-N-ethyl-6-(propan-2-ylamino)-4-(trifluoromethyl)-3-pyridinecarboxamide	aromatic amide		low
N-(4-chlorophenyl)-2,5-dimethyl-1-(thiophen-2-ylmethyl)-3-pyrrolecarboxamide	aromatic amide		low
N-(3,5-dimethylphenyl)-2,5-dimethyl-1-(thiophen-2-ylmethyl)-3-pyrrolecarboxamide	aromatic amide		low
N-(4-chlorophenyl)-5-methyl-2-[(4-methylphenyl)methyl]-3-pyrazolecarboxamide	aromatic amide		low
N-(6-methoxy-3-pyridinyl)-2-thiophenecarboxamide	aromatic amide; thiophenes		low
3-[5-[anilino(oxo)methyl]-2-furanyl]-2-thiophenecarboxylic acid methyl ester	aromatic amide; furans		low
5-(4-morpholinylsulfonyl)-N-[4-(trifluoromethoxy)phenyl]-2-furancarboxamide	aromatic amide; furans		low
5-tert-butyl-N-(4-fluorophenyl)-2-[(4-fluorophenyl)methyl]-3-pyrazolecarboxamide	aromatic amide		low
N-(4-oxo-2-thieno[3,2-d][1,3]thiazinyl)-2-furancarboxamide	aromatic amide; heteroarene		low
5-[[[5-(2-chlorophenyl)-2-(trifluoromethyl)-3-furanyl]-oxomethyl]amino]-2-(4-morpholinyl)benzoic acid methyl ester	aromatic amide; furans		low
2-(4-morpholinyl)-5-[[oxo-[2-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]-3-furanyl]methyl]amino]benzoic acid methyl ester	aromatic amide; furans		low
5-[[[5-(4-chlorophenyl)-2-(trifluoromethyl)-3-furanyl]-oxomethyl]amino]-2-(4-morpholinyl)benzoic acid methyl ester	aromatic amide; furans		low
2-[[(5-tert-butyl-2-methyl-3-furanyl)-oxomethyl]amino]-4,5-dimethoxybenzoic acid methyl ester	aromatic amide; furans		low
N-[3-(aminosulfonyl)phenyl]-2-phenoxynicotinamide	aromatic amide		low
5-tert-butyl-N-[5-(dimethylsulfamoyl)-2-methylphenyl]-2-(phenylmethyl)-3-pyrazolecarboxamide	aromatic amide		low
N'-[4-(3-methoxyphenyl)-2-thiazolyl]-2-thiophenecarbohydrazide	aromatic amide; thiophenes		low
4-(4-chlorophenyl)sulfonyl-N-(2,4-difluorophenyl)-3-methyl-2-thiophenecarboxamide	aromatic amide		low
3-chloro-4-propan-2-ylsulfonyl-2-thiophenecarbohydrazide	aromatic amide; thiophenes		low
N-(2-chlorophenyl)-5-(2-pyridinyl)-2-thiophenecarboxamide	aromatic amide		low
4-hydroxy-3-(methylthio)-4,5,6,7-tetrahydro-2-benzothiophene-1-carbohydrazide	aromatic amide; thiophenes		low
N-phenyl-2-benzo[g][1]benzothiolecarboxamide	1-benzothiophenes; aromatic amide		low
N-(4-methyl-2-nitrophenyl)-2-furancarboxamide	aromatic amide; furans		low
N-(5-nitro-2-pyridinyl)cyclopropanecarboxamide	aromatic amide		low
3-ethyl-N-(2H-tetrazol-5-yl)-1-adamantanecarboxamide	aromatic amide		low
2-[[oxo(thiophen-2-yl)methyl]amino]-6-propyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide	aromatic amide; thiophenes		low
N-(2-hydroxy-5-methylphenyl)-2-furancarboxamide	aromatic amide; furans		low
3-[[[1,3-dioxo-2-(2-oxolanylmethyl)-5-isoindolyl]-oxomethyl]amino]benzoic acid	aromatic amide		low
alanyl-alanyl-alanyl-alanine, (d-ala-l-ala-l-ala-l-ala)-isomer	aromatic amide; furans		low
N-[5-[(4-methylphenyl)methyl]-2-thiazolyl]-2-oxolanecarboxamide	aromatic amide		low
[3-methyl-4-[oxo(thiophen-2-yl)methyl]-1-piperazinyl]-thiophen-2-ylmethanone	aromatic amide; thiophenes		low
N-[(2-ethyl-1-piperidinyl)-sulfanylidenemethyl]-2-thiophenecarboxamide	aromatic amide; thiophenes		low
N-(3,3,5-trimethylcyclohexyl)-1H-1,2,4-triazole-5-carboxamide	aromatic amide; heteroarene		low
6-[[[5-(ethylthio)-1,3,4-thiadiazol-2-yl]amino]-oxomethyl]-1-cyclohex-3-enecarboxylic acid	aromatic amide		low
4-amino-3-(4-ethoxyphenyl)-N-(2-oxolanylmethyl)-2-sulfanylidene-5-thiazolecarboxamide	aromatic amide; thiazoles		low
N-[4-[[[4-(4-methoxyphenyl)-4-oxanyl]methylamino]-oxomethyl]phenyl]-2-furancarboxamide	aromatic amide; furans		low
N4-(4-fluorophenyl)-N5-(2-nitrophenyl)-1H-imidazole-4,5-dicarboxamide	aromatic amide		low
N-[5-(2-oxolanyl)-1,3,4-thiadiazol-2-yl]-2-thiophenecarboxamide	aromatic amide; thiophenes		low
N-(3-carbamoyl-5-propyl-2-thiophenyl)-2-oxolanecarboxamide	aromatic amide; thiophenes		low
N-(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-methyl-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
5-bromo-N-[1-(2,5-dimethylphenyl)ethyl]-2-furancarboxamide	aromatic amide; heteroarene		low
2-[(4-methylphenyl)thio]-N-(1H-1,2,4-triazol-5-yl)propanamide	aromatic amide		low
N-[4-(4-acetyl-1-piperazinyl)-3-chlorophenyl]-2-furancarboxamide	aromatic amide; furans		low
N-(3-cyano-2-thiophenyl)-2-[(1-methyl-2-imidazolyl)thio]acetamide	aromatic amide		low
5-[[[2-[[2-furanyl(oxo)methyl]amino]phenyl]-oxomethoxy]methyl]-3-methyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester	aromatic amide; furans		low
N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)-4-thiophen-2-ylbutanamide	aromatic amide		low
2-[[5-[1-(dimethylamino)ethyl]-4-(phenylmethyl)-1,2,4-triazol-3-yl]thio]-N-(5-methyl-3-isoxazolyl)acetamide	aromatic amide		low
2,2,3,3-tetrafluoro-N-(1H-1,2,4-triazol-5-yl)propanamide	aromatic amide		low
4-[[3-[(4-methylanilino)-oxomethyl]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl]amino]-4-oxobutanoic acid	aromatic amide		low
N-(2-methoxyphenyl)-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide	aromatic amide		low
6-methyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide	aromatic amide; thiophenes		low
N-[3-chloro-4-(4-methyl-1-piperazinyl)phenyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide	aromatic amide		low
N-[2-(3-oxo-4H-quinoxalin-2-yl)phenyl]-2-thiophenecarboxamide	aromatic amide		low
4-amino-N5-(4-butoxyphenyl)-N5-[2-(cyclohexylamino)-2-oxoethyl]isothiazole-3,5-dicarboxamide	aromatic amide		low
N-(4-Butan-2-ylphenyl)-N-[2-(cyclopentylamino)-2-oxo-1-pyridin-3-ylethyl]furan-2-carboxamide	aromatic amide; furans	anticoronaviral agent	low
N-[2-(Cyclopentylamino)-2-oxo-1-pyridin-3-ylethyl]-N-(4-propan-2-ylphenyl)furan-2-carboxamide	aromatic amide; furans	anticoronaviral agent	low
4-amino-3-[(cyclohexylamino)-oxomethyl]-5-isothiazolecarboxylic acid [1-(cyclohexylamino)-1-oxopropan-2-yl] ester	aromatic amide; thiazoles		low
4-[[(4-methyl-5-thieno[3,2-b]pyrrolyl)-oxomethyl]amino]benzoic acid methyl ester	aromatic amide		low
1-[(4-fluorophenyl)methyl]-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-oxo-3H-benzimidazole-5-carboxamide	aromatic amide		low
5-(2-furanyl)-N-(3-pyridinylmethyl)-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
5-bromo-N-[6-[[(5-bromo-2-furanyl)-oxomethyl]amino]-2-pyridinyl]-2-furancarboxamide	aromatic amide; heteroarene		low
N-(2,4-dimethoxyphenyl)-3-[[2-(2-methoxyphenoxy)-1-oxoethyl]amino]-2-benzofurancarboxamide	aromatic amide; furans		low
N-(2,4-dimethoxyphenyl)-3-[[2-furanyl(oxo)methyl]amino]-2-benzofurancarboxamide	aromatic amide; furans		low
N-(2-furanylmethyl)-5-(4-morpholinyl)-4-phenyl-2-thiophenecarboxamide	aromatic amide; thiophenes		low
5-(4-bromophenyl)-N,N-diethyl-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
N-[4-[5-[(2-methylphenoxy)methyl]-1,2,4-oxadiazol-3-yl]phenyl]-2-furancarboxamide	aromatic amide; furans		low
5-[(4-fluorophenyl)methylsulfonylmethyl]-N-(2-oxolanylmethyl)-2-furancarboxamide	aromatic amide; heteroarene		low
N-(5-chloro-2-methoxyphenyl)-2,4-dimethyl-5-oxazolecarboxamide	aromatic amide		low
3-[[oxo(2-quinoxalinyl)methyl]amino]benzoic acid ethyl ester	aromatic amide		low
N-(3-chlorophenyl)-5-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)-3-methyl-2-benzofurancarboxamide	aromatic amide; furans		low
3-[[2-furanyl(oxo)methyl]amino]-N-(4-methoxyphenyl)-2-benzofurancarboxamide	aromatic amide; furans		low
N-(1,1-dioxo-2,3-dihydrothiophen-3-yl)-N-(2-ethylphenyl)-2-thiophenecarboxamide	aromatic amide		low
1-[oxo-[4-oxo-6-[(4-propan-2-ylphenyl)sulfamoyl]-1H-quinolin-3-yl]methyl]-4-piperidinecarboxamide	aromatic amide; quinolines		low
3-methyl-N,6-diphenyl-2-imidazo[2,1-b]thiazolecarboxamide	aromatic amide		low
N-(3,4-dimethoxyphenyl)-7-methoxy-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide	aromatic amide		low
6-[(2-ethylphenyl)sulfamoyl]-N-(2-furanylmethyl)-4-oxo-1H-quinoline-3-carboxamide	aromatic amide; quinolines		low
N-ethyl-3-[4-morpholinyl(oxo)methyl]-4-oxo-N-phenyl-1H-quinoline-6-sulfonamide	aromatic amide; quinolines		low
6-[(2-ethylphenyl)sulfamoyl]-4-oxo-N-(2-oxolanylmethyl)-1H-quinoline-3-carboxamide	aromatic amide; quinolines		low
6-(1-azepanylsulfonyl)-1-ethyl-N-(2-furanylmethyl)-4-oxo-3-quinolinecarboxamide	aromatic amide; quinolines		low
3-(2-chlorophenyl)-5-methyl-N-[3-(3-methyl-2-imidazo[1,2-a]pyrimidinyl)phenyl]-4-isoxazolecarboxamide	aromatic amide		low
N-(4-ethylphenyl)-5-(2-furanyl)-3-isoxazolecarboxamide	aromatic amide		low
N-(2-chlorophenyl)-5-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)-3-methyl-2-benzofurancarboxamide	aromatic amide; furans		low
N4,N5-bis(2-ethoxyphenyl)-1H-imidazole-4,5-dicarboxamide	aromatic amide		low
N-(4-acetylphenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[d]isoxazole-3-carboxamide	aromatic amide		low
N-[1-[(4-fluorophenyl)methyl]-3,5-dimethyl-4-pyrazolyl]-5-(2-furanyl)-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
5-(4-chlorophenyl)-N-(2-furanylmethyl)-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
N-(2,3-dimethylphenyl)-3-methyl-5-(4-morpholinylsulfonyl)-2-benzofurancarboxamide	aromatic amide; furans		low
N-(3,4-dimethylphenyl)-5-(2-furanyl)-3-isoxazolecarboxamide	aromatic amide		low
5-(4-bromophenyl)-N-propan-2-yl-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
N-(3-pyridinyl)-5,6,7,8-tetrahydro-4H-cyclohepta[d]isoxazole-3-carboxamide	aromatic amide; heteroarene		low
N-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-1-methyl-4-oxo-6-(1-pyrrolidinylsulfonyl)-3-quinolinecarboxamide	aromatic amide; quinolines		low
N-butan-2-yl-6-[(4-ethoxyphenyl)sulfamoyl]-4-oxo-1H-quinoline-3-carboxamide	aromatic amide; quinolines		low
1-methyl-6-[(4-methyl-1-piperidinyl)sulfonyl]-3-[oxo(1-piperidinyl)methyl]-4-quinolinone	aromatic amide; quinolines		low
N-(3,4-dimethylphenyl)-3-methyl-5-(4-morpholinylsulfonyl)-2-benzofurancarboxamide	aromatic amide; furans		low
1-methyl-N-(2-methylcyclohexyl)-4-oxo-6-(1-pyrrolidinylsulfonyl)-3-quinolinecarboxamide	aromatic amide; quinolines		low
N-cyclohexyl-5,6,7,8-tetrahydro-4H-cyclohepta[d]isoxazole-3-carboxamide	aromatic amide; heteroarene		low
N-[5-(dimethylsulfamoyl)-2-methylphenyl]-2-quinolinecarboxamide	aromatic amide		low
N-[5-(diethylsulfamoyl)-2-(4-morpholinyl)phenyl]-2-oxo-1H-quinoline-4-carboxamide	aromatic amide		low
3-(2-benzofuranyl)-N-(4-nitrophenyl)-1-phenyl-4-pyrazolecarboxamide	aromatic amide		low
LSM-20806	aromatic amide		low
N-[(4-methoxyphenyl)methyl]-2-(phenylmethyl)-4-thiazolecarboxamide	aromatic amide; thiazoles		low
5-bromo-N-[3-[methyl(phenyl)sulfamoyl]phenyl]-3-pyridinecarboxamide	aromatic amide		low
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-methyl-3-pyrazolecarboxamide	aromatic amide; thiophenes		low
1-butyl-3-[[(4,5-dimethyl-3-thiophenyl)-oxomethyl]amino]thiourea	aromatic amide; thiophenes		low
4-[[3-[anilino(oxo)methyl]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl]amino]-4-oxobutanoic acid	aromatic amide		low
6-bromo-1-(dibromomethyl)-5,5-dimethyl-N-(6-methyl-2-pyridinyl)-4-bicyclo[2.1.1]hexanecarboxamide	aromatic amide		low
N1',N6'-bis[(5-methyl-1H-pyrazol-3-yl)-oxomethyl]hexanedihydrazide	aromatic amide; pyrazoles		low
1-amino-N-methyl-5-(4-morpholinyl)-N-phenyl-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carboxamide	aromatic amide		low
N-(2-fluorophenyl)-6-(1,2,4-triazol-1-yl)-3-pyridinecarboxamide	aromatic amide		low
N-methyl-5-phenyl-2-thiophenecarboxamide	aromatic amide; thiophenes		low
N-(4-fluorophenyl)-5-methyl-1H-indole-2-carboxamide	aromatic amide		low
N-[3-(1,3-dioxo-2-benzo[de]isoquinolinyl)propyl]-N-(2-methoxy-4-methylphenyl)-2-thiophenecarboxamide	aromatic amide		low
N-[3-(dimethylsulfamoyl)-4-methylphenyl]-2-quinolinecarboxamide	aromatic amide		low
N-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]-2-quinolinecarboxamide	aromatic amide		low
N-(2,4-dimethylphenyl)-3-methyl-5-(4-morpholinylsulfonyl)-2-benzofurancarboxamide	aromatic amide; furans		low
N-[3-(1,3-benzothiazol-2-yl)phenyl]-4-oxo-1-benzopyran-2-carboxamide	aromatic amide		low
3-(4-methylphenyl)-N-[3-(4-morpholinylsulfonyl)phenyl]-1-phenyl-4-pyrazolecarboxamide	aromatic amide		low
4-amino-3-(3,4-dimethylphenyl)-N-(2-fluorophenyl)-2-sulfanylidene-5-thiazolecarboxamide	aromatic amide		low
5-oxo-N-[3-(trifluoromethyl)phenyl]-2,3-dihydrothiazolo[3,2-a]pyrimidine-6-carboxamide	aromatic amide		low
N-[5-(2-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-[(4-methyl-1,2,4-triazol-3-yl)thio]butanamide	aromatic amide		low
LSM-19765	aromatic amide		low
N-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-4-oxo-1-benzopyran-2-carboxamide	aromatic amide		low
N-(2,5-dimethoxyphenyl)-4-oxo-3-(2-phenylethyl)-2-sulfanylidene-1H-quinazoline-7-carboxamide	aromatic amide		low
N-[3-(dimethylsulfamoyl)-4-methylphenyl]-5-methyl-2-pyrazinecarboxamide	aromatic amide		low
N-(4-methylphenyl)-6-(1-pyrazolyl)-3-pyridinecarboxamide	aromatic amide		low
N-[4-[(cyclohexylamino)-oxomethyl]phenyl]-3-pyridinecarboxamide	aromatic amide		low
N-[3-[(2,4-dimethylphenyl)sulfamoyl]-4-methylphenyl]-3-oxo-4H-1,4-benzothiazine-6-carboxamide	aromatic amide		low
N-(3-methoxyphenyl)-1,3-dioxo-2-(2-oxolanylmethyl)-5-isoindolecarboxamide	aromatic amide		low
ver-49009	aromatic amide; monochlorobenzenes; monomethoxybenzene; pyrazoles; resorcinols	Hsp90 inhibitor	low
N2,N6-bis[4-(dimethylamino)phenyl]pyridine-2,6-dicarboxamide	aromatic amide		low
2,5-dichloro-N-[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]-3-thiophenecarboxamide	aromatic amide; thiophenes		low
N-[4-[5-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]-4-pyridinecarboxamide	aromatic amide		low
5-(2-chlorophenyl)-N-(4-methoxyphenyl)-2-furancarboxamide	aromatic amide; furans		low
N-[3-(1-azepanylsulfonyl)phenyl]-4-oxo-1-benzopyran-2-carboxamide	aromatic amide		low
N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-3-methyl-5-oxo-6-thiazolo[3,2-a]pyrimidinecarboxamide	aromatic amide		low
N-(2,4-difluorophenyl)-6-(propylthio)-3-pyridinecarboxamide	aromatic amide		low
N,N,4-trimethyl-2-[[(5-methyl-2-furanyl)-oxomethyl]amino]-5-thiazolecarboxamide	aromatic amide; thiazoles		low
5-bromo-N-(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)-2-thiophenecarboxamide	aromatic amide; thiophenes		low
N-[5-(diethylsulfamoyl)-2-(4-morpholinyl)phenyl]-2,3-dihydro-1H-cyclopenta[b]quinoline-9-carboxamide	aromatic amide		low
N-(2-chloro-3-pyridinyl)-2-[[5-(3-methylanilino)-1,3,4-thiadiazol-2-yl]thio]acetamide	aromatic amide		low
N-[5-(4-morpholinylsulfonyl)-2-(1-pyrrolidinyl)phenyl]-2-oxo-1H-quinoline-4-carboxamide	aromatic amide		low
6-chloro-N-[3-[(2-chlorophenyl)sulfamoyl]phenyl]-3-pyridinecarboxamide	aromatic amide		low
N-[4-methoxy-3-(4-morpholinylsulfonyl)phenyl]-5-methyl-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide	aromatic amide		low
N-[5-(diethylsulfamoyl)-2-methoxyphenyl]-5-methyl-3-isoxazolecarboxamide	aromatic amide		low
N-(4-Nitro-1,2,5-oxadiazol-3-yl)-2-pyridin-2-ylsulfanylacetamide	aromatic amide	anticoronaviral agent	low
N-[3-(1,3-dioxo-2-benzo[de]isoquinolinyl)propyl]-N-(4-methoxyphenyl)-2-thiophenecarboxamide	aromatic amide		low
N-(3-carbamoyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-3-(2-chlorophenyl)-5-methyl-4-isoxazolecarboxamide	aromatic amide; thiophenes		low
[3-(2-hydroxyphenyl)-5-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]-thiophen-2-ylmethanone	aromatic amide; thiophenes		low
2-(4,5-dihydrothiazol-2-ylthio)-N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]acetamide	aromatic amide		low
1-butyl-3-[[oxo-(5-propan-2-yl-3-thiophenyl)methyl]amino]thiourea	aromatic amide; thiophenes		low
5-bromo-N-[4-[5-(2-methylphenyl)-1,2,4-oxadiazol-3-yl]phenyl]-2-furancarboxamide	aromatic amide; furans		low
N-[1-[(4-fluorophenyl)methyl]-4-pyrazolyl]-5-(2-furanyl)-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
N-ethyl-3-(1-pyrrolyl)-2-thiophenecarboxamide	aromatic amide; thiophenes		low
N-(4-methoxyphenyl)-5-[2-(trifluoromethyl)phenyl]-2-furancarboxamide	aromatic amide; furans		low
N3-(2,4-dimethylphenyl)-N1-phenylpyrazole-1,3-dicarboxamide	aromatic amide		low
N-[5-(diethylsulfamoyl)-2-(4-morpholinyl)phenyl]-2-oxo-1-benzopyran-3-carboxamide	aromatic amide		low
N-(3-nitrophenyl)-1,3-benzodioxole-5-carboxamide	aromatic amide		low
granisetron	aromatic amide; indazoles		low
N-(3-chlorophenyl)-1H-imidazole-5-carboxamide	aromatic amide		low
N-[3-(3-chlorophenyl)-5-isoxazolyl]-2-(4,5,6,7-tetrahydroindazol-2-yl)acetamide	aromatic amide		low
N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-5-cyclopropyl-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
N-cyclohexyl-5-propyl-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-(2-methylpropyl)-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
2-[[oxo-(5-propyl-3-isoxazolyl)methyl]amino]benzoic acid methyl ester	aromatic amide		low
N-(4-ethylphenyl)-2-(2-furanylmethyl)-1,3-dioxo-5-isoindolecarboxamide	aromatic amide		low
N-(5-bromo-2-hydroxyphenyl)-5-propyl-3-isoxazolecarboxamide	aromatic amide		low
N-(2-ethylphenyl)-5-(3-hydroxyphenyl)-3-isoxazolecarboxamide	aromatic amide		low
N-(3-acetylphenyl)-5-propan-2-yl-3-isoxazolecarboxamide	aromatic amide		low
N,N-dicyclohexyl-5-propyl-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
N-(6-tert-butyl-3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-cyclopropyl-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
5-amino-1-[(3-methoxyphenyl)methyl]-N-(4-methylphenyl)-4-triazolecarboxamide	aromatic amide		low
2-[[cyclohexyl(oxo)methyl]amino]-3-thiophenecarboxamide	aromatic amide; thiophenes		low
5-(4-methyl-1-naphthalenyl)-N-phenyl-2-furancarboxamide	aromatic amide; furans		low
5-(2-methylphenyl)-N-(phenylmethyl)-2-furancarboxamide	aromatic amide; heteroarene		low
N-[3-(7-methyl-2-imidazo[1,2-a]pyridinyl)phenyl]-2-thiophenecarboxamide	aromatic amide		low
2-chloro-N-(1-methyl-3-pyrazolyl)acetamide	aromatic amide		low
N-(5-carbamoyl-2-methoxyphenyl)-3-(2,4-dimethoxyphenyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide	aromatic amide		low
N-(4-chloro-2,5-dimethoxyphenyl)-5-cyclopropyl-3-isoxazolecarboxamide	aromatic amide		low
4-[3-[(3-chloro-4-fluoroanilino)-oxomethyl]-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]-1-piperidinecarboxylic acid tert-butyl ester	aromatic amide		low
N-(4-ethoxyphenyl)-1,5-dimethyl-4-oxo-2-pyrrolo[3,2-c]quinolinecarboxamide	aromatic amide		low
platensimycin	aromatic amide; cyclic ether; cyclic ketone; dihydroxybenzoic acid; monocarboxylic acid amide; polycyclic cage	antibacterial agent; antimicrobial agent; bacterial metabolite; EC 2.3.1.85 (fatty acid synthase) inhibitor	low
granisetron hydrochloride	aromatic amide; indazoles		low
2-chloro-N-[3-(2-thiazolo[5,4-b]pyridinyl)phenyl]-3-pyridinecarboxamide	aromatic amide		low
N-(5-methyl-1,3,4-thiadiazol-2-yl)-2-[[1-(phenylmethyl)-2-imidazolyl]thio]acetamide	aromatic amide		low
N-[5-[(2-methylphenyl)methylthio]-1,3,4-thiadiazol-2-yl]-2-thiophen-2-ylacetamide	aromatic amide		low
a 770041	aromatic amide		low
N-[4-(1-adamantylsulfamoyl)phenyl]-4-bromo-1-methyl-3-pyrazolecarboxamide	aromatic amide		low
N-[3-(3,5-dimethyl-1-piperidinyl)propyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide	aromatic amide; thiophenes		low
4-chloro-N-(4-ethylphenyl)-3-methyl-5-isoxazolecarboxamide	aromatic amide		low
lenvatinib	aromatic amide; aromatic ether; cyclopropanes; monocarboxylic acid amide; monochlorobenzenes; phenylureas; quinolines	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; fibroblast growth factor receptor antagonist; orphan drug; vascular endothelial growth factor receptor antagonist	low
cfm 1571	aromatic amide		low
mirabegron	1,3-thiazoles; aromatic amide; ethanolamines; monocarboxylic acid amide	beta-adrenergic agonist	low
jte 907	aromatic amide; quinolines		low
osi 930	aromatic amide		low
avanafil	aromatic amide; monocarboxylic acid amide; organochlorine compound; prolinols; pyrimidines	EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; vasodilator agent	low
scio-469	aromatic amide; aromatic ketone; chloroindole; dicarboxylic acid diamide; indolecarboxamide; monofluorobenzenes; N-acylpiperazine; N-alkylpiperazine	antineoplastic agent; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor	low
rivaroxaban	aromatic amide; lactam; monocarboxylic acid amide; morpholines; organochlorine compound; oxazolidinone; thiophenes	anticoagulant; EC 3.4.21.6 (coagulation factor Xa) inhibitor	low
2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide	aromatic amide; thiophenes		low
ym 201636	aromatic amide		low
osu 03012	antibiotic antifungal drug; aromatic amide; glycine derivative; organofluorine compound; phenanthrenes; pyrazoles	antineoplastic agent; apoptosis inducer; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor	low
ly-2157299	aromatic amide; methylpyridines; monocarboxylic acid amide; pyrrolopyrazole; quinolines	antineoplastic agent; TGFbeta receptor antagonist	low
tolfenpyrad	aromatic amide; aromatic ether; organochlorine compound; pyrazole insecticide	agrochemical; antifungal agent; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor; mitochondrial NADH:ubiquinone reductase inhibitor	low
azd 7762	aromatic amide; thiophenes		low
ethaboxam	1,3-thiazoles; aromatic amide; aromatic amine; nitrile; secondary amino compound; thiophenes		low
penthiopyrad	aromatic amide; organofluorine compound; pyrazoles; thiophenes		low
[5-hydroxy-3-(4-methoxyphenyl)-5-(trifluoromethyl)-4H-pyrazol-1-yl]-thiophen-2-ylmethanone	aromatic amide; thiophenes		low
VPC 23019	aromatic amide; D-serine derivative; organic phosphate; phosphoric ester; secondary carboxamide	sphingosine-1-phosphate receptor 1 antagonist; sphingosine-1-phosphate receptor 3 antagonist	low
4-[2-(2-chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide	aromatic amide; heteroarene		low
4-cyano-N-[4-(4-methyl-1-piperazinyl)-2-(4-methyl-1-piperidinyl)phenyl]-1H-pyrrole-2-carboxamide	aromatic amide		low
5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]pyrazole-4-carboxamide	aromatic amide; organofluorine compound; pyrazoles		low
n-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1h-pyrazole-4-carboxamide	aromatic amide; cyclopropanes; organofluorine compound; pyrazoles; ring assembly		low
N-[2-methoxy-5-(4-morpholinylsulfonyl)phenyl]-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide	aromatic amide		low
3-(2,4-dimethoxyphenyl)-N-(3-fluoro-4-methylphenyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide	aromatic amide		low
N-Cyclohexyl-5-(2-thienyl)-1,2-oxazole-3-carboxamide	aromatic amide; heteroarene		low
2-[[1,3-dimethyl-7-(4-methylphenyl)-2,4-dioxo-5-pyrimido[4,5-d]pyrimidinyl]thio]-N-(5-methyl-3-isoxazolyl)acetamide	aromatic amide		low
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-methyl-4-nitro-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-methyl-4-nitro-3-isoxazolecarboxamide	aromatic amide; thiophenes		low
N-(4-acetylphenyl)-5,6-dihydro-4H-cyclopenta[d]isoxazole-3-carboxamide	aromatic amide		low
dafadine C	aromatic amide; aromatic ether; difluorobenzene; isoxazoles; N-acylpiperidine; pyridines	P450 inhibitor	low
dafadine B	aromatic amide; aromatic ether; isoxazoles; monochlorobenzenes; monofluorobenzenes; N-acylpiperidine; pyridines	P450 inhibitor	low
5-amino-N-(2-methoxy-5-methylphenyl)-1-[[3-(trifluoromethyl)phenyl]methyl]-4-triazolecarboxamide	aromatic amide		low
vx-770	aromatic amide; monocarboxylic acid amide; phenols; quinolone	CFTR potentiator; orphan drug	low
lumacaftor	aromatic amide; benzodioxoles; benzoic acids; cyclopropanes; organofluorine compound; pyridines	CFTR potentiator; orphan drug	low
platencin	aromatic amide; cyclic ketone; dihydroxybenzoic acid; monocarboxylic acid amide; polycyclic cage	antibacterial agent; antimicrobial agent; bacterial metabolite; EC 2.3.1.85 (fatty acid synthase) inhibitor	low
4-methyl-N-(3-methylbutyl)-5-(5-methyl-3-phenyl-4H-isoxazol-5-yl)-2-thiazolecarboxamide	aromatic amide; thiazoles		low
4-[[[5-[[[(2S)-1-[(2-methylpropan-2-yl)oxy]-6-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-1-oxohexan-2-yl]amino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]benzoic acid ethyl ester	aromatic amide; tert-butyl ester		low
2-[[[4-[(3-methylanilino)-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]acetic acid (phenylmethyl) ester	aromatic amide		low
N4-(4-methoxyphenyl)-N5-[(1S)-1-phenylethyl]-1H-imidazole-4,5-dicarboxamide	aromatic amide		low
2-[[[4-[(4-chloroanilino)-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]acetic acid tert-butyl ester	aromatic amide; tert-butyl ester		low
(2S)-2-[[[4-[(4-chloroanilino)-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]-6-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]hexanoic acid tert-butyl ester	aromatic amide; tert-butyl ester		low
(2S)-2-[[[4-[[4-[[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]methyl]anilino]-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]propanoic acid tert-butyl ester	aromatic amide; tert-butyl ester		low
N4-(4-methoxyphenyl)-N5-[(1R)-1-phenylethyl]-1H-imidazole-4,5-dicarboxamide	aromatic amide		low
amg 1	aromatic amide		low
N-(2-aminophenyl)-2-pyrazinecarboxamide	aromatic amide		low
5-(3-hydroxyphenyl)-N-[2-(4-morpholinyl)ethyl]-3-isoxazolecarboxamide	aromatic amide; heteroarene		low
n-cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide	aromatic amide; heteroarene		low
N-(5-chloro-2,4-dimethoxyphenyl)-1-methyl-4-(4-morpholinylsulfonyl)-2-pyrrolecarboxamide	aromatic amide		low
4-(1-((5-((2,6-dimethylphenoxy)methyl)-3-isoxazolyl)carbonyl)-4-piperidinyl)pyridine	aromatic amide; aromatic ether; isoxazoles; N-acylpiperidine; pyridines	geroprotector; P450 inhibitor	low
dafadine D	aromatic amide; aromatic ether; isoxazoles; N-acylpiperidine; organofluorine compound; pyridines	P450 inhibitor	low
dafadine O	aromatic amide; aromatic ether; isoxazoles; N-acylpiperidine; pyridines; ring assembly	P450 inhibitor	low
bms 777607	aromatic amide		low
suvorexant	1,3-benzoxazoles; aromatic amide; diazepine; organochlorine compound; triazoles	central nervous system depressant; orexin receptor antagonist	low
N-[(2R,3S)-2-[[[[(3,5-dimethyl-4-isoxazolyl)amino]-oxomethyl]-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]-4,4,4-trifluorobutanamide	aromatic amide		low
N-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[oxo-(propan-2-ylamino)methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]cyclopropanecarboxamide	aromatic amide		low
N-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-(methylaminomethyl)-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]cyclopropanecarboxamide	aromatic amide		low
N-[(2S,3S)-2-[[[[(3,5-dimethyl-4-isoxazolyl)amino]-oxomethyl]-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4,4,4-trifluorobutanamide	aromatic amide		low
N-[(2S,3S)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4,4,4-trifluorobutanamide	aromatic amide		low
N-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[oxo-(propan-2-ylamino)methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]cyclopropanecarboxamide	aromatic amide		low
N-[(2R,3S)-2-[[cyclopropylmethyl(methyl)amino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]-4,4,4-trifluorobutanamide	aromatic amide		low
N-[(2S,3S)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]cyclohexanecarboxamide	aromatic amide		low
5-(2,5-difluorophenyl)-N-(2,6-dimethylphenyl)-2-furancarboxamide	aromatic amide; furans		low
5-(2,5-dichlorophenyl)-N-(2,6-dimethoxyphenyl)-2-furancarboxamide	aromatic amide; furans		low
5-(2,5-dichlorophenyl)-N-[2,6-di(propan-2-yl)phenyl]-2-furancarboxamide	aromatic amide; furans		low
5-(2,5-dichlorophenyl)-N-(2,6-diethylphenyl)-2-furancarboxamide	aromatic amide; furans		low
N-(2,6-dimethylphenyl)-5-(4-methyl-3-thiophenyl)-2-furancarboxamide	aromatic amide; furans		low
N-[(1R)-2-(tert-butylamino)-2-oxo-1-(3-pyridinyl)ethyl]-N-(4-tert-butylphenyl)-2-furancarboxamide	aromatic amide; furans		low
fluazaindolizine	aromatic amide; imidazopyridine; monocarboxylic acid amide; monochlorobenzenes; monomethoxybenzene; N-sulfonylcarboxamide; organofluorine pesticide	agrochemical; nematicide	low
ve 821	aromatic amide		low
N-[2-(3-oxo-4H-quinoxalin-2-yl)-4-propan-2-ylphenyl]-2-thiophenecarboxamide	aromatic amide		low
N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide	aromatic amide; bridged compound; olefinic compound; organochlorine compound; organofluorine compound; pyrazoles		low
coumermycin	aromatic amide; coumarins; glycoside; heteroarenecarboxylate ester; pyrroles	antimicrobial agent; antineoplastic agent; bacterial metabolite; DNA synthesis inhibitor; Hsp90 inhibitor; topoisomerase IV inhibitor	low
1-butyl-4-hydroxy-N-(3-methyl-2-pyridinyl)-2-oxo-3-quinolinecarboxamide	aromatic amide; quinolines		low
roquinimex	aromatic amide		low
N-(2-chlorophenyl)-4-hydroxy-2-oxo-1-pentyl-3-quinolinecarboxamide	aromatic amide		low
4-hydroxy-1-(2-methylpropyl)-2-oxo-N-(2-sulfamoylphenyl)-3-quinolinecarboxamide	aromatic amide		low
4-hydroxy-2-oxo-1-propyl-N-(pyridin-4-ylmethyl)-3-quinolinecarboxamide	aromatic amide; quinolines		low
lfm a13	aromatic amide; dibromobenzene; enamide; enol; nitrile; secondary carboxamide	antineoplastic agent; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; EC 2.7.11.21 (polo kinase) inhibitor; geroprotector; platelet aggregation inhibitor	low
laquinimod	aromatic amide		low
N-[(4-chlorophenyl)methyl]-4-hydroxy-2-oxo-1-prop-2-enyl-3-quinolinecarboxamide	aromatic amide; quinolines		low
4-hydroxy-2-oxo-N-[3-(trifluoromethyl)phenyl]-1H-quinoline-3-carboxamide	aromatic amide		low
4-hydroxy-1-methyl-2-oxo-N-(4-oxo-2-propyl-3-quinazolinyl)-3-quinolinecarboxamide	aromatic amide; quinolines		low
1-butyl-N-[(4-chlorophenyl)methyl]-4-hydroxy-2-oxo-3-quinolinecarboxamide	aromatic amide; quinolines		low
N'-[(2-chlorophenyl)-oxomethyl]-1-ethyl-4-hydroxy-2-oxo-3-quinolinecarbohydrazide	aromatic amide; quinolines		low
4-hydroxy-1-methyl-N'-[(3-methylphenyl)-oxomethyl]-2-oxo-3-quinolinecarbohydrazide	aromatic amide; quinolines		low
N-(2-aminophenyl)-1-butyl-4-hydroxy-2-oxo-3-quinolinecarboxamide	aromatic amide		low
4-hydroxy-2-oxo-1-prop-2-enyl-N-(3-pyridinyl)-3-quinolinecarboxamide	aromatic amide; quinolines		low
LSM-23565	aromatic amide; quinolines		low
1-ethyl-4-hydroxy-2-oxo-N'-(1-oxoheptyl)-3-quinolinecarbohydrazide	aromatic amide; quinolines		low
1-ethyl-N-(2-fluorophenyl)-4-hydroxy-2-oxo-3-quinolinecarboxamide	aromatic amide		low
N-(2-aminophenyl)-4-hydroxy-2-oxo-1-pentyl-3-quinolinecarboxamide	aromatic amide		low
teriflunomide	(trifluoromethyl)benzenes; aromatic amide; enamide; enol; nitrile; secondary carboxamide	drug metabolite; EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor; hepatotoxic agent; non-steroidal anti-inflammatory drug; tyrosine kinase inhibitor	low
1-ethyl-4-hydroxy-2-oxo-N'-(1-oxodecyl)-3-quinolinecarbohydrazide	aromatic amide; quinolines		low
LSM-31922	aromatic amide; quinolines		low
1-ethyl-4-hydroxy-2-oxo-N-(3-pyridinylmethyl)-3-quinolinecarboxamide	aromatic amide; quinolines		low
N-(1H-benzimidazol-2-yl)-1-ethyl-4-hydroxy-2-oxo-3-quinolinecarboxamide	aromatic amide; quinolines		low
N-[(3,4-dimethoxyphenyl)methyl]-4-hydroxy-2-oxo-1-propyl-3-quinolinecarboxamide	aromatic amide; quinolines		low
4-hydroxy-N-(2-methyl-4-oxo-3-quinazolinyl)-1-(2-methylpropyl)-2-oxo-5,6,7,8-tetrahydroquinoline-3-carboxamide	aromatic amide; quinolines		low
4-hydroxy-1-(2-methylpropyl)-2-oxo-N-[4-oxo-2-(phenylmethyl)-3-quinazolinyl]-5,6,7,8-tetrahydroquinoline-3-carboxamide	aromatic amide; quinolines		low
4-hydroxy-2-oxo-1-pentyl-N-(2-pyridinylmethyl)-3-quinolinecarboxamide	aromatic amide; quinolines		low
N-[2-(4-chlorophenyl)ethyl]-4-hydroxy-2-oxo-1-propyl-3-quinolinecarboxamide	aromatic amide; quinolines		low
abt-267	aromatic amide; carbamate ester; dipeptide; pyrrolidines	antiviral drug; hepatitis C virus nonstructural protein 5A inhibitor	low
3-(difluoromethyl)-N-methoxy-1-methyl-N-[1-(2,4,6-trichlorophenyl)propan-2-yl]pyrazole-4-carboxamide	aromatic amide; monocarboxylic acid amide; organofluorine compound; pyrazoles; trichlorobenzene		low
AKB48	aromatic amide; indazoles		low
Adb-fubinaca	aromatic amide; indazoles		low
n-(1-adamantyl)-1-(5-fluoropentyl)-1h-indazole-3-carboxamide	aromatic amide; indazoles		low
4-chloro-N-[(4-chlorophenyl)methyl]-3-nitro-1H-pyrazole-5-carboxamide	aromatic amide; heteroarene		low
1-[4-[[oxo-(7-oxo-4H-isothiazolo[4,3-d]pyrimidin-3-yl)methyl]amino]phenyl]-3-piperidinecarboxylic acid ethyl ester	aromatic amide		low
1-[4-[[(5-methyl-7-oxo-4H-isothiazolo[4,3-d]pyrimidin-3-yl)-oxomethyl]amino]phenyl]-3-piperidinecarboxylic acid ethyl ester	aromatic amide		low
5-(3-hydroxymethyl-3-methyl-1-triazeno)imidazole-4-carboxamide	aromatic amide; heteroarene		low
ver 52296	aromatic amide; isoxazoles; monocarboxylic acid amide; morpholines; resorcinols	angiogenesis inhibitor; antineoplastic agent; Hsp90 inhibitor	low
dabigatran etexilate	aromatic amide; benzimidazoles; beta-alanine derivative; carboxamidine; carboxylic ester; pyridines	anticoagulant; EC 3.4.21.5 (thrombin) inhibitor; prodrug	low
bay h 4502	biphenyls; imidazoles		low
candesartan cilexetil	biphenyls		low
4-biphenylylacetic acid	biphenyls; monocarboxylic acid	non-steroidal anti-inflammatory drug	low
fenbufen	4-oxo monocarboxylic acid; biphenyls	non-steroidal anti-inflammatory drug	low
3,3'-dichlorobenzidine	biphenyls; monochlorobenzenes; organochlorine compound		low
3,3'-diaminobenzidine	biphenyls; substituted aniline	histological dye	low
diphenyl	aromatic fungicide; benzenes; biphenyls	antifungal agrochemical; antimicrobial food preservative	low
benzidine	biphenyls; substituted aniline	carcinogenic agent	low
4-nitrobiphenyl	biphenyls		low
dianisidine	biphenyls		low
2-tolidine	biphenyls		low
n,n'-diacetylbenzidine	biphenyls		low
2-amino-4-phenylphenol	biphenyls		low
4-acetylaminobiphenyl	biphenyls		low
4-biphenylylacetic acid ethyl ester	biphenyls		low
brequinar	biphenyls; monocarboxylic acid; monofluorobenzenes; quinolinemonocarboxylic acid	anticoronaviral agent; antimetabolite; antineoplastic agent; antiviral agent; EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor; immunosuppressive agent; pyrimidine synthesis inhibitor	low
tasosartan	biphenyls		low
telmisartan	benzimidazoles; biphenyls; carboxybiphenyl	angiotensin receptor antagonist; antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; environmental contaminant; xenobiotic	low
clobuzarit	biphenyls; organochlorine compound		low
magnolol	biphenyls		low
honokiol	biphenyls		low
bitertanol	aromatic ether; biphenyls; secondary alcohol; triazoles		low
isodiospyrin	biphenyls		low
difenpiramide	biphenyls; monocarboxylic acid amide; pyridines	antipyretic; non-narcotic analgesic; non-steroidal anti-inflammatory drug	low
2-(4-phenylphenoxy)propanoic acid	biphenyls		low
4-hydroxy-2',4',6'-trichlorobiphenyl	biphenyls; trichlorobenzene		low
4-hydroxy-2',3',4'-5'-tetrachlorobiphenyl	biphenyls; tetrachlorobenzene		low
dityrosine	biphenyls; non-proteinogenic alpha-amino acid; tyrosine derivative	biomarker	low
4,4'-bis(methylsulfonyl)-2,2',5,5'-tetrachlorobiphenyl	biphenyls; dichlorobenzene; sulfone		low
nitroflurbiprofen	biphenyls; carboxylic ester; nitrate ester; organofluorine compound	cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; EC 1.14.13.39 (nitric oxide synthase) inhibitor; geroprotector; non-steroidal anti-inflammatory drug; vasodilator agent	low
olmesartan medoxomil	biphenyls		low
4'-hydroxyflurbiprofen	biphenyls		low
dehydrodieugenol	biphenyls		low
bifeprunox	biphenyls		low
2-chloro-n-(4-chlorobiphenyl-2-yl)nicotinamide	anilide fungicide; biphenyls; monochlorobenzenes; pyridinecarboxamide	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor; environmental contaminant; xenobiotic	low
aucuparin	biphenyls		low
2-[(3,4-dimethoxyphenyl)methyl]-5-[4-(4-methoxyphenyl)phenyl]-1,3,4-oxadiazole	biphenyls		low
2-(2,5-dimethoxyphenyl)-5-[4-(4-methoxyphenyl)phenyl]-1,3,4-oxadiazole	biphenyls		low
(2'-(benzyloxycarbonylaminomethyl)biphenyl-2-carboxylic acid 2-(2-pyridyl)ethylamide)	biphenyls		low
4-phenylbenzoic acid (propan-2-ylideneamino) ester	biphenyls		low
N-[[(6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-4-phenylbenzamide	biphenyls		low
4-phenyl-N-(2-propyl-5-tetrazolyl)benzamide	biphenyls		low
2-[(1-methyl-5-tetrazolyl)thio]-N-(2-phenylphenyl)acetamide	biphenyls		low
3-phenyl-5-(2-phenylphenyl)-1,2,4-oxadiazole	biphenyls		low
N-[[methyl-(phenylmethyl)amino]-sulfanylidenemethyl]-4-phenylbenzamide	biphenyls		low
N-[4-[4-(ethylsulfonylamino)-3-methoxyphenyl]-2-methoxyphenyl]ethanesulfonamide	biphenyls		low
urb 597	biphenyls		low
3-(4-phenylphenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepine	biphenyls		low
ac 55649	biphenyls; carboxybiphenyl		low
1-[3-(4-phenylphenoxy)propyl]-1,2,4-triazole	biphenyls		low
N-[2-(2-phenylphenoxy)ethyl]-2-furancarboxamide	biphenyls		low
2-(2-phenylanilino)-N-(phenylmethyl)acetamide	biphenyls		low
4-(2-fluorophenyl)-N-(2-methylbut-3-yn-2-yl)benzamide	biphenyls		low
5-oxo-3-(4-phenylphenyl)-2H-furan-4-carbonitrile	biphenyls		low
N-([biphenyl]-2-yl)-3-cyclopentylpropanamide	biphenyls; cyclopentanes; secondary carboxamide		low
1-(4-morpholinyl)-2-(4-phenylphenoxy)-1-propanone	biphenyls		low
2-(4-morpholinyl)-N-(2-phenylphenyl)propanamide	biphenyls		low
4-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]benzonitrile	biphenyls; nitrile		low
3-[4-[(2-hydroxy-5-phenylphenyl)methyl]-1-piperazinyl]propanenitrile	biphenyls		low
N-(2-methoxyethyl)-4-[4-(2-methoxyethylsulfamoyl)phenyl]benzenesulfonamide	biphenyls		low
2-phenylbutanoic acid [2-oxo-2-(2-phenylanilino)ethyl] ester	biphenyls		low
2-(4-benzoyl-1-piperazinyl)-N-(2-phenylphenyl)propanamide	biphenyls		low
fexaramine	biphenyls		low
alx 5407	biphenyls		low
bay 12-9566	biphenyls; organochlorine compound		low
sacubitril	biphenyls		low
biphenyl-indanone a	biphenyls		low
fimasartan	biphenyls		low
2-[[4-(4-bromophenyl)phenyl]sulfonylamino]-3-methylbutanoic acid	biphenyls; organobromine compound		low
l-161982	biphenyls		low
N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide	1,3,4-oxadiazoles; benzamides; biphenyls; nitrile	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor	low
abt-737	aromatic amine; aryl sulfide; biphenyls; C-nitro compound; monochlorobenzenes; N-arylpiperazine; N-sulfonylcarboxamide; secondary amino compound; tertiary amino compound	anti-allergic agent; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; B-cell lymphoma 2 inhibitor	low
4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide	biphenyls		low
ly2183240	biphenyls		low
(3R,3aS,7R,7aS)-3-[4-[4-(dimethylamino)phenyl]-2-fluorophenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one	biphenyls		low
3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide	biphenyls		low
WWL113	biphenyls		low
lde225	aminopyridine; aromatic ether; benzamides; biphenyls; morpholines; organofluorine compound; tertiary amino compound	antineoplastic agent; Hedgehog signaling pathway inhibitor; SMO receptor antagonist	low
N-[3-(3-chlorophenyl)phenyl]-1-(3-isoxazolylmethyl)-4-piperidinecarboxamide	biphenyls; organochlorine compound		low
N-[3-(3-chlorophenyl)phenyl]-1-(3-oxolanylmethyl)-4-piperidinecarboxamide	biphenyls; organochlorine compound		low
4-(4-acetyloxyphenyl)benzoic acid [2-[[2-(2-chloroanilino)-2-oxoethyl]-methylamino]-2-oxoethyl] ester	biphenyls		low
N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide	benzamides; biphenyls; cyclopropanes; dicarboxylic acid diamide	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor	low
tak-875	biphenyls		low
bms-790052	biphenyls; carbamate ester; carboxamide; imidazoles; valine derivative	antiviral drug; nonstructural protein 5A inhibitor	low
(2S)-2-[[2-(2,3-dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol	biphenyls		low
4-[(1-methyl-5-tetrazolyl)thio]-5-(4-phenylphenyl)thieno[2,3-d]pyrimidine	biphenyls; thienopyrimidine		low
ml228 probe	1,2,4-triazines; biphenyls; pyridines; secondary amino compound	hypoxia-inducible factor pathway activator	low
a 769662	biphenyls		low
am 251	amidopiperidine; carbohydrazide; dichlorobenzene; organoiodine compound; pyrazoles	antidepressant; antineoplastic agent; apoptosis inducer; CB1 receptor antagonist	low
celecoxib	organofluorine compound; pyrazoles; sulfonamide; toluenes	cyclooxygenase 2 inhibitor; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug	low
dipyrone	amino sulfonic acid; pyrazoles	anti-inflammatory agent; antipyretic; antirheumatic drug; cyclooxygenase 3 inhibitor; non-narcotic analgesic; peripheral nervous system drug; prodrug	low
famprofazone	pyrazoles; ring assembly		low
fipronil	(trifluoromethyl)benzenes; dichlorobenzene; nitrile; primary amino compound; pyrazoles; sulfoxide		low
fomepizole	pyrazoles	antidote; EC 1.1.1.1 (alcohol dehydrogenase) inhibitor; protective agent	low
nifenazone	pyrazoles; ring assembly		low
1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
ramifenazone	pyrazoles; ring assembly		low
sulfaphenazole	primary amino compound; pyrazoles; substituted aniline; sulfonamide antibiotic; sulfonamide	antibacterial drug; EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor; EC 1.14.13.67 (quinine 3-monooxygenase) inhibitor; P450 inhibitor	low
betazole	primary amino compound; pyrazoles	diagnostic agent; gastrointestinal drug; histamine agonist	low
5-methylpyrazole-3-carboxylic acid	monocarboxylic acid; pyrazoles	metabolite	low
noramidopyrine	pyrazoles; secondary amino compound	antipyretic; drug metabolite; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; opioid analgesic; peripheral nervous system drug	low
difenzoquat	pyrazoles; ring assembly		low
tepoxalin	aromatic ether; hydroxamic acid; monochlorobenzenes; pyrazoles	antipyretic; apoptosis inhibitor; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; immunomodulator; lipoxygenase inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug	low
n-acetylaminoantipyrine	acetamides; pyrazoles	drug metabolite; marine xenobiotic metabolite	low
lonazolac	monocarboxylic acid; monochlorobenzenes; pyrazoles	antineoplastic agent; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug	low
n-demethylantipyrine	pyrazoles; ring assembly		low
4-Formyl-antipyrine	pyrazoles; ring assembly		low
4-iodopyrazole	organoiodine compound; pyrazoles		low
5-amino-1-phenyl-1H-pyrazole-4-carbonitrile	pyrazoles; ring assembly		low
ethyl 5-(4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl)-1-methylpyrazole-4-carboxylate	pyrazoles		low
halosulfuron methyl	pyrazoles		low
pyraclofos	monochlorobenzenes; organic thiophosphate; organochlorine insecticide; organosulfur compound; organothiophosphate insecticide; pyrazoles	agrochemical; EC 3.1.1.7 (acetylcholinesterase) inhibitor	low
benzpiperylone	pyrazoles; ring assembly		low
4-hydroxyantipyrine	pyrazoles; ring assembly		low
sr141716	amidopiperidine; carbohydrazide; dichlorobenzene; monochlorobenzenes; pyrazoles	anti-obesity agent; appetite depressant; CB1 receptor antagonist	low
sc 58125	organofluorine compound; pyrazoles; sulfone	antineoplastic agent; cyclooxygenase 2 inhibitor	low
3-phenyl-1H-pyrazole-5-carboxylic acid	pyrazoles; ring assembly		low
birb 796	aromatic ether; morpholines; naphthalenes; pyrazoles; ureas	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; immunomodulator	low
cgs 20625	pyrazoles; ring assembly		low
chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 3	pyrazoles; ring assembly		low
N-tert-butyl-6-ethyl-1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
4-methyl-7-phenyl-3-pyrazolo[5,1-c][1,2,4]triazinecarboxylic acid ethyl ester	pyrazoles; ring assembly		low
4-amino-2,6-dimethyl-5-[3-(4-methylphenyl)-1H-pyrazol-5-yl]-3-pyridazinone	pyrazoles; ring assembly		low
1-(3-tert-butyl-1-methylpyrazol-5-yl)-3-(4-chlorophenyl)urea	monochlorobenzenes; phenylureas; pyrazoles	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor	low
hts 466284	pyrazoles; pyridines; quinolines	TGFbeta receptor antagonist	low
1-phenyl-4-pyrazolol	pyrazoles; ring assembly		low
3-pentyl-4,5,6,7-tetrahydro-1H-indazole	pyrazoles		low
7-amino-2-methyl-3-phenyl-6-pyrazolo[1,5-a]pyrimidinecarbonitrile	pyrazoles; ring assembly		low
4-[2-(3-fluorophenyl)-5-methyl-7-pyrazolo[1,5-a]pyrimidinyl]morpholine	pyrazoles; ring assembly		low
4-[2-(3-fluorophenyl)-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolin-9-yl]morpholine	pyrazoles; ring assembly		low
2-[[2-(4-methoxyphenyl)-5-methyl-7-pyrazolo[1,5-a]pyrimidinyl]amino]ethanol	pyrazoles; ring assembly		low
4-[3-(4-fluorophenyl)-2,5,6-trimethyl-7-pyrazolo[1,5-a]pyrimidinyl]morpholine	pyrazoles; ring assembly		low
2-[2-[[2-[[1-(4-methoxyphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]thio]-1-oxoethyl]amino]-4-thiazolyl]acetic acid ethyl ester	pyrazoles; ring assembly		low
LSM-34623	pyrazoles; ring assembly		low
5-(2-methylpropyl)-1H-pyrazole-3-carboxylic acid	pyrazoles		low
2-[[1-(4-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]thio]acetic acid ethyl ester	pyrazoles; ring assembly		low
2-[(3-oxo-5-phenyl-1,2-dihydropyrazol-4-yl)-(3-thiophenyl)methyl]propanedinitrile	pyrazoles; ring assembly		low
N-[2-(1-cyclohexenyl)ethyl]-1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
N-(2-oxolanylmethyl)-1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
1-phenyl-N-(3-propan-2-yloxypropyl)-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
2-[2-[[1-(4-chlorophenyl)-4-pyrazolo[3,4-d]pyrimidinyl]amino]ethoxy]ethanol	pyrazoles; ring assembly		low
1-(4-chlorophenyl)-N-(1-methoxypropan-2-yl)-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
1-[1-(4-methoxyphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]-4-piperidinecarboxamide	pyrazoles; ring assembly		low
2-[2-[(1-phenyl-4-pyrazolo[3,4-d]pyrimidinyl)amino]ethoxy]ethanol	pyrazoles; ring assembly		low
LSM-17424	pyrazoles; ring assembly		low
LSM-19719	pyrazoles; ring assembly		low
LSM-28231	pyrazoles; ring assembly		low
2,6-dimethyl-4-(1-phenyl-4-pyrazolyl)furo[2,3-d]pyrimidine	pyrazoles; ring assembly		low
Glyceryl lactopalmitate	pyrazoles; ring assembly		low
2-[(2,5-dimethyl-3-phenyl-7-pyrazolo[1,5-a]pyrimidinyl)thio]acetonitrile	pyrazoles; ring assembly		low
7-(3,5-dimethyl-1-pyrazolyl)-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidine	pyrazoles; ring assembly		low
6-amino-1-(4-fluorophenyl)-3-methyl-4-thiophen-2-yl-5-pyrazolo[3,4-b]pyridinecarbonitrile	pyrazoles; ring assembly		low
4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazol-5-amine	pyrazoles; ring assembly		low
2-(4-bromophenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine	pyrazoles; ring assembly		low
2-(4-bromophenyl)-4-methyl-1H-pyrazol-5-one	pyrazoles; ring assembly		low
1-(3-methylphenyl)-N-(2-pyridinylmethyl)-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
1,3-diphenyl-4-pyrazolecarbonitrile	pyrazoles; ring assembly		low
N-tert-butyl-1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
5-(4-cyclohexylphenyl)-1,2-dihydropyrazol-3-one	pyrazoles; ring assembly		low
2-(3-oxo-2-phenyl-1H-pyrazol-5-yl)acetic acid methyl ester	pyrazoles; ring assembly		low
4-hydroxy-1-(4-methylphenyl)-3-pyrazolecarboxylic acid ethyl ester	pyrazoles; ring assembly		low
1-(4-fluorophenyl)-4-hydroxy-3-pyrazolecarboxylic acid ethyl ester	pyrazoles; ring assembly		low
4-(3,5-dimethyl-1-pyrazolyl)-6-methyl-1-phenylpyrazolo[3,4-d]pyrimidine	pyrazoles; ring assembly		low
5,7-dimethyl-2-phenylpyrazolo[1,5-a]pyrimidine	pyrazoles; ring assembly		low
5-(methoxymethyl)-2-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-one	pyrazoles; ring assembly		low
3-(4-chlorophenyl)-2,5-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one	pyrazoles; ring assembly		low
2-(5,7-dimethyl-3-phenyl-6-pyrazolo[1,5-a]pyrimidinyl)acetic acid ethyl ester	pyrazoles; ring assembly		low
5,7-dimethyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine	pyrazoles; ring assembly		low
(3-methyl-1-phenyl-5-thieno[2,3-c]pyrazolyl)-(3-methyl-1-pyrazolyl)methanone	pyrazoles; ring assembly		low
3-(4-ethoxyphenyl)-1H-pyrazole-5-carbohydrazide	pyrazoles; ring assembly		low
3-[2-(4-fluorophenyl)-5-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-6-yl]propanoic acid ethyl ester	pyrazoles; ring assembly		low
3-(4-methoxyphenyl)-1H-pyrazole-5-carbohydrazide	pyrazoles; ring assembly		low
3-phenyl-5,6,7,8-tetrahydro-1H-pyrazolo[5,1-b]quinazolin-9-one	pyrazoles; ring assembly		low
7,8-dimethoxy-5-methyl-3-phenylpyrazolo[3,4-c]isoquinoline	pyrazoles; ring assembly		low
7,8-dimethoxy-1,5-dimethyl-3-phenylpyrazolo[3,4-c]isoquinoline	pyrazoles; ring assembly		low
4-[(4-chlorophenyl)thio]-5-methyl-2-phenyl-1H-pyrazol-3-one	pyrazoles; ring assembly		low
5-methyl-1-phenyl-4-pyrazolecarboxylic acid (4-methoxyphenyl) ester	pyrazoles; ring assembly		low
5-(4-methylphenyl)-2-phenyl-3-pyrazolamine	pyrazoles; ring assembly		low
N-(4-fluorophenyl)-1-(3-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
4-methoxy-2-[3-(4-methoxyphenyl)-5-methyl-1H-pyrazol-4-yl]phenol	pyrazoles; ring assembly		low
5-amino-3-ethyl-1-phenyl-4-pyrazolecarbonitrile	pyrazoles; ring assembly		low
1-(4-methylphenyl)sulfonyl-4-phenyl-3-pyrazolamine	pyrazoles; ring assembly		low
LSM-16463	pyrazoles; ring assembly		low
N-cyclopropyl-3-methyl-1-phenyl-5-thieno[2,3-c]pyrazolecarboxamide	pyrazoles; ring assembly		low
7-amino-2-(4-tert-butylphenyl)-6-pyrazolo[1,5-a]pyrimidinecarboxylic acid ethyl ester	pyrazoles; ring assembly		low
cct018159	benzodioxine; pyrazoles; resorcinols	antineoplastic agent; apoptosis inducer; Hsp90 inhibitor	low
2-(4-ethoxyphenyl)-3,4-dimethyl-7-[2-(1-pyrrolidinyl)ethylthio]pyrazolo[3,4-d]pyridazine	pyrazoles; ring assembly		low
8-[1-(3-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]-1,4-dioxa-8-azaspiro[4.5]decane	pyrazoles; ring assembly		low
3-(4-chlorophenyl)-5-propyl-1H-pyrazolo[1,5-a]pyrimidin-7-one	pyrazoles; ring assembly		low
2,5-dimethyl-3-phenyl-7-pyrazolo[1,5-a]pyrimidinamine	pyrazoles; ring assembly		low
3-methyl-N'-(1-oxo-2-phenoxyethyl)-1-phenyl-5-thieno[2,3-c]pyrazolecarbohydrazide	pyrazoles; ring assembly		low
4-[(3,5-dichloro-2-hydroxyphenyl)methylamino]-1,5-dimethyl-2-phenyl-3-pyrazolone	pyrazoles; ring assembly		low
1-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-3-(4-methylphenyl)sulfonylurea	pyrazoles; ring assembly		low
2-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-3-one	pyrazoles; ring assembly		low
N-[[3-(4-fluorophenyl)-1-phenyl-4-pyrazolyl]methyl]-1-phenylmethanamine	pyrazoles; ring assembly		low
4-(5-amino-4-phenyl-1-pyrazolyl)benzoic acid	pyrazoles; ring assembly		low
N-(3,4-dimethoxyphenyl)-1-(3-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
LSM-28273	pyrazoles; ring assembly		low
N'-[2-[[1-(4-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]thio]-1-oxoethyl]-2-furancarbohydrazide	pyrazoles; ring assembly		low
1-[4-(2-fluorophenyl)-2-thiazolyl]-5-(trifluoromethyl)-4-pyrazolecarboxylic acid ethyl ester	pyrazoles		low
1-methyl-5-[(4-methylphenyl)thio]-3-phenyl-4-pyrazolecarbonitrile	pyrazoles; ring assembly		low
3-phenyl-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine	pyrazoles; ring assembly		low
4-(2,5-dimethoxyphenyl)-3-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1H-1,2,4-triazole-5-thione	pyrazoles; ring assembly		low
5-tert-butyl-3-(4-chlorophenyl)-N-(2-pyridinylmethyl)-7-pyrazolo[1,5-a]pyrimidinamine	pyrazoles; ring assembly		low
LSM-20639	pyrazoles; ring assembly		low
6-[[(4-chlorophenyl)thio]methyl]-2-phenyl-1,7-dihydropyrazolo[3,4-b]pyridine-3,4-dione	pyrazoles; ring assembly		low
4-(2,5-dimethoxyphenyl)-3-(3-phenyl-1H-pyrazol-5-yl)-1H-1,2,4-triazole-5-thione	pyrazoles; ring assembly		low
N-[5-methyl-2-(4-methylphenyl)-3-pyrazolyl]-2-[(7-methyl-4-oxo-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-9-yl)oxy]acetamide	pyrazoles; ring assembly		low
5-tert-butyl-2-methyl-3-phenyl-N-(2-pyridinylmethyl)-7-pyrazolo[1,5-a]pyrimidinamine	pyrazoles; ring assembly		low
1-(4-methoxyphenyl)-N-[2-(4-morpholinyl)ethyl]-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
N-(5-tert-butyl-2-phenyl-3-pyrazolyl)-2-[(6-methyl-1H-benzimidazol-2-yl)thio]acetamide	pyrazoles; ring assembly		low
N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-3-(2-methylphenoxy)propanamide	pyrazoles; ring assembly		low
N-[4-(4-methyl-2-thiazolyl)-2-phenyl-3-pyrazolyl]-3-(trifluoromethyl)benzamide	pyrazoles; ring assembly		low
1-(4-fluorophenyl)-3-methyl-5-thieno[2,3-c]pyrazolecarboxylic acid [2-(methylamino)-2-oxoethyl] ester	pyrazoles; ring assembly		low
2-chloro-N-[3-(4-methylphenyl)-1-phenyl-4-pyrazolyl]acetamide	pyrazoles; ring assembly		low
3-(4-methoxyphenyl)-1-phenyl-4-pyrazolamine	pyrazoles; ring assembly		low
N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-2,5-diphenyl-3-pyrazolecarboxamide	pyrazoles; ring assembly		low
2-chloro-N-(2-phenyl-5-propyl-3-pyrazolyl)acetamide	pyrazoles; ring assembly		low
2,2,2-trifluoro-N-(5-oxo-1-phenyl-4H-pyrazol-3-yl)acetamide	pyrazoles; secondary carboxamide; trifluoroacetamide		low
N-(5-methyl-2-phenyl-3-pyrazolyl)-2-phenoxyacetamide	pyrazoles; ring assembly		low
1-phenyl-N-(3-pyridinylmethyl)-3-thiophen-2-yl-4-pyrazolecarboxamide	pyrazoles; ring assembly		low
N-[[2-(diethylamino)ethylamino]-sulfanylidenemethyl]-3-(4-methoxyphenyl)-1-phenyl-4-pyrazolecarboxamide	pyrazoles; ring assembly		low
3-(4-methoxyphenyl)-N-[[[oxo(pyridin-4-yl)methyl]hydrazo]-sulfanylidenemethyl]-1-phenyl-4-pyrazolecarboxamide	pyrazoles; ring assembly		low
3-methyl-N,1-diphenyl-4-pyrazolecarbothioamide	pyrazoles; ring assembly		low
1-(2-chlorophenyl)-N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-3-methyl-5-thieno[2,3-c]pyrazolecarboxamide	pyrazoles; ring assembly		low
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-(3,5-dimethyl-1-pyrazolyl)benzamide	pyrazoles; ring assembly		low
3-[2-[(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)amino]-2-oxoethyl]-4-oxo-1-phthalazinecarboxylic acid	pyrazoles; ring assembly		low
5-(4-propylphenyl)-1H-pyrazol-3-amine	pyrazoles; ring assembly		low
N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-2-[(6-methyl-1H-benzimidazol-2-yl)thio]acetamide	pyrazoles; ring assembly		low
3-methyl-1-phenyl-5-thieno[2,3-c]pyrazolecarboxylic acid [2-(butylamino)-2-oxoethyl] ester	pyrazoles; ring assembly		low
N2-[5-(4-chlorophenyl)-2-phenyl-3-pyrazolyl]benzene-1,2-diamine	pyrazoles; ring assembly		low
N2-[2-(4-methylphenyl)-5-phenyl-3-pyrazolyl]benzene-1,2-diamine	pyrazoles; ring assembly		low
N2-(5-phenyl-1H-pyrazol-3-yl)benzene-1,2-diamine	pyrazoles; ring assembly		low
2-phenyl-5-thiophen-2-yl-3-pyrazolecarboxylic acid [2-(3-nitroanilino)-2-oxoethyl] ester	pyrazoles; ring assembly		low
2-phenyl-5-thiophen-2-yl-3-pyrazolecarboxylic acid [2-(2-chloro-5-nitroanilino)-2-oxoethyl] ester	pyrazoles; ring assembly		low
2-phenyl-5-thiophen-2-yl-3-pyrazolecarboxylic acid [2-(4-chloro-3-nitroanilino)-2-oxoethyl] ester	pyrazoles; ring assembly		low
N-[[(4-oxo-1-phenyl-5-pyrazolo[3,4-d]pyrimidinyl)amino]-sulfanylidenemethyl]benzamide	pyrazoles; ring assembly		low
N2-[5-(3-chlorophenyl)-2-phenyl-3-pyrazolyl]benzene-1,2-diamine	pyrazoles; ring assembly		low
2-phenyl-5-sulfanylidene-3,7,8,9,10,11-hexahydropyrazolo[4,5]pyrimido[3,5-a]azepin-1-one	pyrazoles; ring assembly		low
3-(3,4-dimethylphenyl)-1-(phenylmethyl)-4-pyrazolecarboxaldehyde	pyrazoles; ring assembly		low
5-chloro-1-[(2-chlorophenyl)methyl]-3-methyl-4-pyrazolecarboxylic acid [2-[(5-methyl-3-isoxazolyl)amino]-2-oxoethyl] ester	pyrazoles		low
4-(3-methyl-1-phenyl-1H-pyrazolo[3,4-b]quinolin-4-yl)morpholine	pyrazoles; ring assembly		low
3-(tert-butyl)-1-methyl-4,5-dihydro-1H-pyrazol-5-one	pyrazoles		low
2,5-bis(3,5-dimethyl-1-phenyl-4-pyrazolyl)-1,3,4-oxadiazole	pyrazoles; ring assembly		low
4-(3-methylphenyl)-2-(3-nitrophenyl)-3-pyrazolamine	pyrazoles; ring assembly		low
4-(4-methylphenyl)-2-(3-nitrophenyl)-3-pyrazolamine	pyrazoles; ring assembly		low
3-(2,4-dichlorophenyl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole	pyrazoles; ring assembly		low
2-(3,5-dimethyl-1-pyrazolyl)benzonitrile	pyrazoles; ring assembly		low
ethyl 1-[4-(4-chlorobenzenesulfonamido)phenyl]-5-(trifluoromethyl)pyrazole-4-carboxylate	ethyl ester; monochlorobenzenes; organofluorine compound; pyrazoles; sulfonamide		low
1-(4-fluorophenyl)-3-[4-(4-fluorophenyl)-2-methyl-5-(trifluoromethyl)-3-pyrazolyl]urea	pyrazoles; ring assembly		low
3,3-dimethyl-5-oxo-5-[(3-phenyl-1H-pyrazol-5-yl)amino]pentanoic acid	pyrazoles; ring assembly		low
1-[(4-chlorophenyl)-oxomethyl]-5-hydroxy-5-phenyl-4H-pyrazole-3-carboxylic acid methyl ester	pyrazoles; ring assembly		low
4-(5-methyl-3-oxo-1H-pyrazol-2-yl)benzoic acid	pyrazoles; ring assembly		low
4-[1-(4-chlorophenyl)-4-pyrazolo[3,4-d]pyrimidinyl]-2,6-dimethylmorpholine	pyrazoles; ring assembly		low
1-(4-methoxyphenyl)-N,N-dipropyl-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
2-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-3-hydroxy-3-phenyl-1-isoindolone	pyrazoles; ring assembly		low
2-(1,3-diphenyl-4-pyrazolyl)-3-(2-furanylmethyl)-4-thiazolidinone	pyrazoles; ring assembly		low
3-(4-fluorophenyl)-N-[3-(1-imidazolyl)propyl]-1-phenyl-4-pyrazolecarboxamide	pyrazoles; ring assembly		low
1-(4-fluorophenyl)-3-methyl-5-thieno[2,3-c]pyrazolecarboxylic acid (2-oxo-3-oxolanyl) ester	pyrazoles; ring assembly		low
3,5-dimethyl-1-phenyl-4-pyrazolecarboxylic acid [2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxo-5-pyrimidinyl]-2-oxoethyl] ester	pyrazoles; ring assembly		low
deracoxib	organofluorine compound; pyrazoles; sulfonamide	cyclooxygenase 2 inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug	low
fipronil sulfone	(trifluoromethyl)benzenes; dichlorobenzene; nitrile; pyrazoles; sulfone	marine xenobiotic metabolite	low
sr 144528	bridged compound; monochlorobenzenes; pyrazoles; secondary carboxamide	CB2 receptor antagonist; EC 2.3.1.26 (sterol O-acyltransferase) inhibitor	low
4-methyl-3-phenyl-1H-pyrazole-5-carbohydrazide	pyrazoles; ring assembly		low
3-(4-fluorophenyl)-5-(2-furanyl)-2-phenyl-3,4-dihydropyrazole	pyrazoles; ring assembly		low
2-[[3-methyl-5-oxo-1-(phenylmethyl)-4H-pyrazol-4-yl]-phenylmethyl]propanedinitrile	pyrazoles		low
7-(2-ethyl-1-piperidinyl)-5-methyl-2-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine	pyrazoles; ring assembly		low
N-(2,4-dimethoxyphenyl)-2-[1-(3,4-dimethylphenyl)-4-oxo-5-pyrazolo[3,4-d]pyrimidinyl]acetamide	pyrazoles; ring assembly		low
N-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-1,3-benzodioxole-5-carboxamide	pyrazoles; ring assembly		low
N-(3-chlorophenyl)-2-[1-(3,4-dimethylphenyl)-4-oxo-5-pyrazolo[3,4-d]pyrimidinyl]acetamide	pyrazoles; ring assembly		low
1-(4-chlorophenyl)-5-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]-4-pyrazolecarboxylic acid	pyrazoles; ring assembly		low
N-[2-(2,3-dimethylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-methoxybenzamide	pyrazoles; ring assembly		low
3-(4-bromophenyl)-1H-pyrazole-5-carboxylic acid methyl ester	pyrazoles; ring assembly		low
5-methyl-N-(5-methyl-2-phenyl-3-pyrazolyl)-3-isoxazolecarboxamide	pyrazoles; ring assembly		low
2-(4-ethoxyphenyl)-5-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]-6-pyrazolo[1,5-a]pyrimidinecarboxylic acid	pyrazoles; ring assembly		low
5-tert-butyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid	pyrazoles		low
3-[5-amino-3-(4-chlorophenyl)-1-pyrazolyl]propanoic acid ethyl ester	pyrazoles; ring assembly		low
3-methyl-N-[2-(4-morpholinyl)ethyl]-1-phenyl-5-thieno[2,3-c]pyrazolecarboxamide	pyrazoles; ring assembly		low
1-[2-(1-oxo-2-thiophen-2-ylethoxy)ethyl]-5-[(1-oxo-2-thiophen-2-ylethyl)amino]-4-pyrazolecarboxylic acid ethyl ester	pyrazoles		low
1,3-diphenyl-4-pyrazolecarboxylic acid [2-[(3,5-dichloro-2-pyridinyl)amino]-2-oxoethyl] ester	pyrazoles; ring assembly		low
4-[3-(1,3-diphenyl-4-pyrazolyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-4-oxobutanoic acid	pyrazoles; ring assembly		low
gtp 14564	pyrazoles; ring assembly		low
2-amino-7,7-dimethyl-5-oxo-4-[1-phenyl-3-(4-propan-2-ylphenyl)-4-pyrazolyl]-6,8-dihydro-4H-1-benzopyran-3-carbonitrile	pyrazoles; ring assembly		low
5-[3-[3-(4-methoxyphenyl)-1-phenyl-4-pyrazolyl]-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-5-oxopentanoic acid	pyrazoles; ring assembly		low
4-[1-(4-bromophenyl)-2-nitroethyl]-5-methyl-2-phenyl-1H-pyrazol-3-one	pyrazoles; ring assembly		low
5-chloro-4-[methoxy(phenyl)methyl]-1-methyl-3-phenylpyrazole	pyrazoles; ring assembly		low
5-methyl-3-phenyl-7-(prop-2-enylthio)pyrazolo[1,5-a]pyrimidine	pyrazoles; ring assembly		low
2-[4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-piperidinyl]-3-nitropyridine	pyrazoles; ring assembly		low
2-[[1-(4-chlorophenyl)-4-pyrazolo[3,4-d]pyrimidinyl]amino]-1-butanol	pyrazoles; ring assembly		low
4-[(2-hydroxy-3-nitrophenyl)-(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methyl]-5-methyl-2-phenyl-1H-pyrazol-3-one	pyrazoles; ring assembly		low
N-butan-2-yl-2-[[3-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-4-oxo-2-quinazolinyl]thio]acetamide	pyrazoles; ring assembly		low
7-(1-azepanyl)-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidine	pyrazoles; ring assembly		low
5-methyl-4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-(3-nitrophenyl)methyl]-2-phenyl-1H-pyrazol-3-one	pyrazoles; ring assembly		low
4-(3,5-dimethyl-1-pyrazolyl)benzoic acid [2-(4-chloro-2-nitroanilino)-2-oxoethyl] ester	pyrazoles; ring assembly		low
am 281	pyrazoles; ring assembly		low
sc 560	aromatic ether; monochlorobenzenes; organofluorine compound; pyrazoles	angiogenesis modulating agent; antineoplastic agent; apoptosis inducer; cyclooxygenase 1 inhibitor; non-steroidal anti-inflammatory drug	low
LSM-28389	pyrazoles; ring assembly		low
LSM-16826	pyrazoles; ring assembly		low
1-(4-methoxyphenyl)-N-(2-oxolanylmethyl)-4-pyrazolo[3,4-d]pyrimidinamine	pyrazoles; ring assembly		low
4-[1-(4-fluorophenyl)-2-nitroethyl]-5-methyl-2-phenyl-1H-pyrazol-3-one	pyrazoles; ring assembly		low
3-(4-ethoxyphenyl)-N-[(1-methyl-4-piperidinylidene)amino]-1H-pyrazole-5-carboxamide	pyrazoles; ring assembly		low
6-[5-chloro-3-methyl-1-(4-methylphenyl)-4-pyrazolyl]-3,4-dimethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylic acid ethyl ester	pyrazoles; ring assembly		low
N-[3-(1-imidazolyl)propyl]-2-methyl-3-phenyl-5-propyl-7-pyrazolo[1,5-a]pyrimidinamine	pyrazoles; ring assembly		low
5-tert-butyl-3-(4-chlorophenyl)-7-(2-ethyl-1-imidazolyl)pyrazolo[1,5-a]pyrimidine	pyrazoles; ring assembly		low
5-methyl-2-phenyl-4-propan-2-ylidene-3-pyrazolone	pyrazoles		low
1,3,5-tris(4-hydroxyphenyl)-4-propyl-1h-pyrazole	phenols; pyrazoles	estrogen receptor agonist	low
4-[1-(2,4-dichlorophenyl)-2-nitroethyl]-5-(2-hydroxyphenyl)-1,2-dihydropyrazol-3-one	pyrazoles; ring assembly		low
[5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-3-pyrazolyl]-(4-morpholinyl)methanone	pyrazoles; ring assembly		low
4-[3-(2-chloro-1-oxoethyl)-2,5-dimethyl-1-pyrrolyl]-1,5-dimethyl-2-phenyl-3-pyrazolone	pyrazoles; ring assembly		low
N-(2-methoxyethyl)-2-(5-methyl-4,5,6,7-tetrahydroindazol-2-yl)acetamide	pyrazoles		low
2-(4-fluoro-3-methylphenyl)sulfonyl-5-(2-methoxyphenyl)-3-pyrazolamine	pyrazoles; ring assembly		low
4-[[[3-(2-fluorophenyl)-1-methyl-5-thieno[2,3-c]pyrazolyl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester	pyrazoles; ring assembly		low
3-(4-chlorophenyl)-N-cyclopropyl-1-methyl-5-thieno[2,3-c]pyrazolecarboxamide	pyrazoles; ring assembly		low
3-(4-chlorophenyl)-1-methyl-N-[(5-methyl-2-furanyl)methyl]-5-thieno[2,3-c]pyrazolecarboxamide	pyrazoles; ring assembly		low
N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-1-(1H-imidazol-5-ylsulfonyl)-3-piperidinecarboxamide	pyrazoles; ring assembly		low
3-(4-chlorophenyl)-1-methyl-N-[3-(1-pyrrolidinyl)propyl]-5-thieno[2,3-c]pyrazolecarboxamide	pyrazoles; ring assembly		low
4-[3-(4-fluorophenyl)-2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]-1-piperidinecarboxylic acid ethyl ester	pyrazoles; ring assembly		low
N-(6-acetyl-1,3-benzodioxol-5-yl)-5-methyl-2-phenyl-3-pyrazolecarboxamide	pyrazoles; ring assembly		low
3-(4-chlorophenyl)-N-[2-(diethylamino)ethyl]-1-methyl-5-thieno[2,3-c]pyrazolecarboxamide	pyrazoles; ring assembly		low
GSK3-XIII	aromatic amine; pyrazoles; quinazolines; secondary amino compound	EC 2.7.11.26 (tau-protein kinase) inhibitor	low
pyrachlostrobin	aromatic ether; carbamate ester; carbanilate fungicide; methoxycarbanilate strobilurin antifungal agent; monochlorobenzenes; pyrazoles	antifungal agrochemical; environmental contaminant; mitochondrial cytochrome-bc1 complex inhibitor; xenobiotic	low
2-(4-methoxyphenyl)-5-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]-6-pyrazolo[1,5-a]pyrimidinecarboxylic acid ethyl ester	pyrazoles; ring assembly		low
N-(phenylmethyl)-3-[3,4,6-trimethyl-1-(4-methylphenyl)-5-pyrazolo[3,4-b]pyridinyl]propanamide	pyrazoles; ring assembly		low
2-(2,1,3-benzothiadiazol-4-ylsulfonyl)-5-(4-chlorophenyl)-3-pyrazolamine	pyrazoles; ring assembly		low
4-(5-(4-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazol-1-yl)benzenesulfonamide	organofluorine compound; pyrazoles; sulfonamide	cyclooxygenase 2 inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug	low
sr 147778	pyrazoles; ring assembly		low
sd 0006	monochlorobenzenes; N-acylpiperidine; primary alcohol; pyrazoles; pyrimidines		low
ethiprole	pyrazoles; ring assembly		low
1-(2,4-dichlorophenyl)-6-methyl-N-(1-piperidinyl)-4H-indeno[1,2-c]pyrazole-3-carboxamide	pyrazoles; ring assembly		low
cc 401	pyrazoles; ring assembly		low
at 7867	monochlorobenzenes; piperidines; pyrazoles	antineoplastic agent; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor	low
4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol	pyrazoles; ring assembly		low
chlorantranilipole	monochlorobenzenes; organobromine compound; pyrazole insecticide; pyrazoles; pyridines; secondary carboxamide	ryanodine receptor agonist	low
at 7519	dichlorobenzene; piperidines; pyrazoles; secondary carboxamide	antineoplastic agent; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor	low
fr 180204	pyrazoles; ring assembly		low
azd 1152	anilide; monoalkyl phosphate; monofluorobenzenes; pyrazoles; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; Aurora kinase inhibitor; prodrug	low
GDC-0879	indanes; ketoxime; primary alcohol; pyrazoles; pyridines	antineoplastic agent; B-Raf inhibitor	low
2-(2,1,3-benzothiadiazol-4-ylsulfonyl)-5-(4-bromophenyl)-3-pyrazolamine	pyrazoles; ring assembly		low
pyriprole	pyrazoles; ring assembly		low
3-[2-(4-chlorophenyl)-5,7-dimethyl-6-pyrazolo[1,5-a]pyrimidinyl]-N-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]propanamide	pyrazoles; ring assembly		low
azd 1152-hqpa	anilide; monofluorobenzenes; primary alcohol; pyrazoles; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; Aurora kinase inhibitor	low
3-[2-(3,5-dimethoxyphenyl)-5,7-dimethyl-6-pyrazolo[1,5-a]pyrimidinyl]-N-(phenylmethyl)propanamide	pyrazoles; ring assembly		low
[3-(4-bromophenyl)-1H-pyrazol-5-yl]-[4-(3,4-dimethoxyphenyl)sulfonyl-1-piperazinyl]methanone	pyrazoles; ring assembly		low
3-[3-(4-fluorophenyl)-2,5,7-trimethyl-6-pyrazolo[1,5-a]pyrimidinyl]-N-(2-methoxyphenyl)propanamide	pyrazoles; ring assembly		low
N-[[3-(2-chlorophenyl)-1-(4-fluorophenyl)-4-pyrazolyl]methyl]-2-(2-pyridinyl)ethanamine	pyrazoles; ring assembly		low
(3aS,5S,9aS)-5-[1-(2-methoxyphenyl)-4-pyrazolyl]-2-phenyl-3a,4,5,7,8,9-hexahydro-3H-pyrrolo[3,4-h]pyrrolizin-1-one	pyrazoles; ring assembly		low
1-[[3-(3-fluorophenyl)-1-(4-methoxyphenyl)-4-pyrazolyl]methyl]-4-methoxypiperidine	pyrazoles; ring assembly		low
N-[[5-(2,4-difluorophenyl)-1H-pyrazol-4-yl]methyl]-1-(3-thiophenyl)-2-propanamine	pyrazoles; ring assembly		low
N-[[3-(3-methylphenyl)-1-(4-methylphenyl)-4-pyrazolyl]methyl]-3-(1-pyrazolyl)-1-propanamine	pyrazoles; ring assembly		low
1-(1,5-dimethyl-3-pyrazolyl)-N-[[5-(2-fluoro-4-methoxyphenyl)-1H-pyrazol-4-yl]methyl]methanamine	pyrazoles; ring assembly		low
(1R,5S)-6-[[5-(2-fluoro-4-methoxyphenyl)-1H-pyrazol-4-yl]methyl]-6-azabicyclo[3.2.1]octane	pyrazoles; ring assembly		low
1-[[3-(4-fluorophenyl)-1-(4-methylphenyl)-4-pyrazolyl]methyl]-4-[(1-methyl-2-imidazolyl)methyl]piperazine	pyrazoles; ring assembly		low
(3aS,5S,9aS)-2-[(2-methylphenyl)methyl]-5-(1-methyl-3-phenyl-4-pyrazolyl)-3a,4,5,7,8,9-hexahydro-3H-pyrrolo[3,4-h]pyrrolizin-1-one	pyrazoles; ring assembly		low
2-(3,5-dimethyl-1-pyrazolyl)-N-[[3-(4-fluorophenyl)-1-(4-methylphenyl)-4-pyrazolyl]methyl]ethanamine	pyrazoles; ring assembly		low
1-[[3-(2-fluorophenyl)-1-methyl-4-pyrazolyl]methyl]-3-propoxypiperidine	pyrazoles; ring assembly		low
N'-[1-(3,4-dimethylphenyl)-4-pyrazolo[3,4-d]pyrimidinyl]acetohydrazide	pyrazoles; ring assembly		low
5-(4-chlorophenyl)-2-(4-methoxyphenyl)sulfonyl-3-pyrazolamine	pyrazoles; ring assembly		low
1-hydroxy-2-(5-phenyl-1H-pyrazol-3-yl)-4H-1,2,4-benzotriazin-3-one	pyrazoles; ring assembly		low
2-[[1-(4-fluorophenyl)-4-pyrazolo[3,4-d]pyrimidinyl]thio]-N-(2-oxolanylmethyl)acetamide	pyrazoles; ring assembly		low
cyenopyrafen	nitrile; pivalate ester; pyrazoles	agrochemical; proacaricide	low
sgx 523	aryl sulfide; biaryl; pyrazoles; quinolines; triazolopyridazine	c-Met tyrosine kinase inhibitor; nephrotoxic agent	low
bms 754807	pyrazoles; pyridines; pyrrolidines; pyrrolotriazine	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor	low
N-[1-(3-fluorophenyl)-6,6-dimethyl-5,7-dihydro-4H-indazol-4-yl]-2-(2-pyridinylthio)acetamide	pyrazoles; ring assembly		low
N-[1-(2,3-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,5-dimethyl-3-pyrazolecarboxamide	pyrazoles; ring assembly		low
N-[1-(4-tert-butylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-4-methyl-5-thiadiazolecarboxamide	pyrazoles; ring assembly		low
N-[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,5-dimethyl-3-pyrazolecarboxamide	pyrazoles; ring assembly		low
N-[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-5-(methoxymethyl)-2-furancarboxamide	pyrazoles; ring assembly		low
N-[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2-(3,5-dimethyl-1-pyrazolyl)acetamide	pyrazoles; ring assembly		low
dcc-2036	organofluorine compound; phenylureas; pyrazoles; pyridinecarboxamide; quinolines	tyrosine kinase inhibitor	low
incb-018424	nitrile; pyrazoles; pyrrolopyrimidine	antineoplastic agent; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor	low
baricitinib	azetidines; nitrile; pyrazoles; pyrrolopyrimidine; sulfonamide	anti-inflammatory agent; antirheumatic drug; antiviral agent; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; immunosuppressive agent	low
gsk 1070916	pyrazoles; ring assembly		low
gsk-5498a	(trifluoromethyl)benzenes; difluorobenzene; pyrazoles; secondary carboxamide	calcium channel blocker	low
azd4547	benzamides; N-arylpiperazine; pyrazoles	fibroblast growth factor receptor antagonist	low
oxathiapiprolin	1,3-thiazoles; isoxazoline; N-acylpiperidine; organofluorine compound; pyrazoles; tertiary carboxamide		low
LimKi 3	1,3-thiazoles; dichlorobenzene; organofluorine compound; pyrazoles; secondary carboxamide	LIM kinase inhibitor	low
pf-06463922	aminopyridine; aromatic ether; azamacrocycle; benzamides; cyclic ether; monofluorobenzenes; nitrile; organic heterotetracyclic compound; pyrazoles	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor	low
CCT251545	azaspiro compound; chloropyridine; pyrazoles	antineoplastic agent; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor; Wnt signalling inhibitor	low
ldc4297	aromatic ether; piperidines; pyrazoles; pyrazolotriazine; secondary amino compound	antineoplastic agent; antiviral agent; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor	low
praliciguat	aminopyrimidine; isoxazoles; monofluorobenzenes; organofluorine compound; pyrazoles; secondary amino compound; tertiary alcohol	anti-inflammatory agent; antihypertensive agent; soluble guanylate cyclase activator; vasodilator agent	low
can 508	aromatic amine; monoazo compound; phenols; pyrazoles	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor	low
N-[3-[(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)amino]-1-isoindolylidene]-2-thiophenecarboxamide	pyrazoles; ring assembly		low
pyrazofurin	C-glycosyl compound; pyrazoles	antimetabolite; antimicrobial agent; antineoplastic agent; EC 4.1.1.23 (orotidine-5'-phosphate decarboxylase) inhibitor	low
3-amino-2-phenyl-2H-pyrazolo[4,3-c]pyridine-4,6-diol	pyrazoles; ring assembly		low
4-methyl-3-phenyl-1,2-dihydropyrazolo[3,4-b]pyridin-6-one	pyrazoles; ring assembly		low
hydrazinocurcumin	aromatic ether; olefinic compound; polyphenol; pyrazoles	angiogenesis modulating agent; antineoplastic agent; EC 2.3.1.48 (histone acetyltransferase) inhibitor; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor	low
5-(4-chlorophenyl)-3-(4-nitrophenyl)-1H-pyrazole	pyrazoles; ring assembly		low
sitagliptin	triazolopyrazine; trifluorobenzene	EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor; environmental contaminant; hypoglycemic agent; serine proteinase inhibitor; xenobiotic	low
atogepant	azaspiro compound; organic heterotetracyclic compound; piperidones; secondary carboxamide; trifluorobenzene	calcitonin gene-related peptide receptor antagonist	low
bictegravir	monocarboxylic acid amide; organic heterotetracyclic compound; secondary carboxamide; trifluorobenzene	HIV-1 integrase inhibitor	low
carboxin	anilide fungicide; anilide; enamide; organosulfur heterocyclic compound; oxacycle; secondary carboxamide	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	low
oxycarboxin	anilide fungicide; anilide; organosulfur heterocyclic compound; oxacycle; sulfone	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	low
Metsulfovax	anilide fungicide; anilide		low
n-(3-chloro-4-methylphenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide	anilide fungicide; monocarboxylic acid amide; monochlorobenzenes; organosulfur compound; thiadiazoles	antifungal agrochemical	low
mefenoxam	acylamino acid fungicide; anilide fungicide; D-alanine derivative; methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate	agrochemical	low

Substance	Classes	Roles	Relationship Strength
3-nitropropionic acid	C-nitro compound	antimycobacterial drug; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor; mycotoxin; neurotoxin	low
carboxin	anilide fungicide; anilide; enamide; organosulfur heterocyclic compound; oxacycle; secondary carboxamide	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	low
oxycarboxin	anilide fungicide; anilide; organosulfur heterocyclic compound; oxacycle; sulfone	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	low
flutolanil	(trifluoromethyl)benzenes; aromatic ether; benzamides; benzanilide fungicide	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	low
thifluzamide	1,3-thiazoles; anilide fungicide; aromatic amide; aromatic ether; dibromobenzene; organofluorine compound	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	low
2-chloro-n-(4-chlorobiphenyl-2-yl)nicotinamide	anilide fungicide; biphenyls; monochlorobenzenes; pyridinecarboxamide	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor; environmental contaminant; xenobiotic	low
tolfenpyrad	aromatic amide; aromatic ether; organochlorine compound; pyrazole insecticide	agrochemical; antifungal agent; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor; mitochondrial NADH:ubiquinone reductase inhibitor	low
oxyquinoline	monohydroxyquinoline	antibacterial agent; antifungal agrochemical; antiseptic drug; iron chelator	low
bithionol	aryl sulfide; bridged diphenyl antifungal drug; bridged diphenyl fungicide; dichlorobenzene; organochlorine pesticide; polyphenol	antifungal agrochemical; antiplatyhelmintic drug	low
ethoxyquin	aromatic ether; quinolines	antifungal agrochemical; food antioxidant; genotoxin; geroprotector; herbicide; Hsp90 inhibitor; neuroprotective agent; UDP-glucuronosyltransferase activator	low
liquid crystal polymer	conazole fungicide; dichlorobenzene; organobromine compound; oxolanes; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor	low
guazatine	aliphatic nitrogen antifungal agent; guanidines; secondary amino compound	antifungal agrochemical	low
hexachlorophene	bridged diphenyl fungicide; polyphenol; trichlorobenzene	acaricide; antibacterial agent; antifungal agrochemical; antiseptic drug	low
thiabendazole	1,3-thiazoles; benzimidazole fungicide; benzimidazoles	antifungal agrochemical; antinematodal drug	low
thiram	organic disulfide	antibacterial drug; antifungal agrochemical; antiseptic drug	low
chloropicrin	C-nitro compound; one-carbon compound; organochlorine compound	antifungal agrochemical; fumigant insecticide; nematicide	low
quintozene	aromatic fungicide; C-nitro compound; pentachlorobenzenes	antifungal agrochemical	low
2-phenylphenol	hydroxybiphenyls	antifungal agrochemical; environmental food contaminant	low
diphenyl	aromatic fungicide; benzenes; biphenyls	antifungal agrochemical; antimicrobial food preservative	low
dicloran	aromatic fungicide; dichlorobenzene; nitroaniline	antifungal agrochemical	low
dyrene	monochlorobenzenes; organochlorine pesticide; secondary amino compound; triazines	antifungal agrochemical	low
tecnazene	aromatic fungicide; C-nitro compound; tetrachlorobenzene	antifungal agrochemical	low
hexachlorobenzene	aromatic fungicide; chlorobenzenes	antifungal agrochemical; carcinogenic agent; persistent organic pollutant	low
captan	isoindoles; organochlorine compound; organosulfur compound; phthalimide fungicide	antifungal agrochemical	low
folpet	organochlorine compound; organosulfur compound; phthalimide fungicide	antifungal agrochemical	low
ziram	dithiocarbamate salt; zinc molecular entity	antifungal agrochemical; apoptosis inducer	low
dazomet	dithiocarbamic ester; thiadiazinane	antibacterial agent; antifungal agrochemical; herbicide; nematicide	low
diphenylamine	aromatic amine; bridged diphenyl fungicide; secondary amino compound	antifungal agrochemical; antioxidant; carotogenesis inhibitor; EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor; ferroptosis inhibitor; radical scavenger	low
triphenyltin chloride	chlorine molecular entity; organotin compound	antifungal agrochemical; immunosuppressive agent	low
n-dichlorofluoromethylthio-n',n'-dimethyl-n-p-tolylsulfamide	organochlorine compound; organofluorine compound; phenylsulfamide fungicide; sulfamides	antifungal agrochemical; genotoxin	low
dichlofluanid	organochlorine compound; organofluorine compound; phenylsulfamide fungicide; sulfamides	acaricide; antifungal agrochemical	low
2-allylphenol	phenols	antifungal agrochemical	low
tetrachloroisophthalonitrile	aromatic fungicide; dinitrile; tetrachlorobenzene	antifungal agrochemical	low
captafol	isoindoles; organochlorine compound; organosulfur compound; phthalimide fungicide	antifungal agrochemical	low
dodine	acetate salt; aliphatic nitrogen antifungal agent	antibacterial agent; antifungal agrochemical	low
etridiazol	aromatic ether; organochlorine compound; thiadiazole antifungal agent; thiadiazoles	antifungal agrochemical; nitrification inhibitor	low
chloroneb	aromatic fungicide; dichlorobenzene; dimethoxybenzene	antifungal agrochemical	low
dithianone	dinitrile; naphthodithiin; p-quinones	antifungal agrochemical	low
streptomycin	antibiotic antifungal drug; antibiotic fungicide; streptomycins	antibacterial drug; antifungal agrochemical; antimicrobial agent; antimicrobial drug; bacterial metabolite; protein synthesis inhibitor	low
fuberidazole	benzimidazole fungicide; benzimidazoles; furans	antifungal agrochemical	low
hymexazol	heteroaryl hydroxy compound; isoxazoles	antifungal agrochemical	low
carbendazim	benzimidazole fungicide; benzimidazoles; benzimidazolylcarbamate fungicide; carbamate ester	antifungal agrochemical; antinematodal drug; metabolite; microtubule-destabilising agent	low
pyrazophos	ethyl ester; organic thiophosphate; pyrazolopyrimidine	antifungal agrochemical; insecticide; phospholipid biosynthesis inhibitor; profungicide	low
edifenphos	organic thiophosphate	antifungal agrochemical; EC 3.1.1.7 (acetylcholinesterase) inhibitor; neurotoxin; phospholipid biosynthesis inhibitor	low
benomyl	aromatic amide; benzimidazole fungicide; benzimidazoles; benzimidazolylcarbamate fungicide; carbamate ester	acaricide; anthelminthic drug; antifungal agrochemical; microtubule-destabilising agent; tubulin modulator	low
propamocarb	carbamate ester; carbamate fungicide; tertiary amino compound	antifungal agrochemical; environmental contaminant; xenobiotic	low
tridemorph	morpholines; tertiary amino compound	antifungal agrochemical	low
o,o-diisopropyl-s-benzylthiophosphate	organic thiophosphate	antifungal agrochemical; phospholipid biosynthesis inhibitor	low
2-n-octyl-4-isothiazolin-3-one	1,2-thiazoles	antibacterial agent; antifungal agrochemical; environmental contaminant; xenobiotic	low
triforine	amide fungicide; formamides; N-alkylpiperazine; organochlorine compound	allergen; antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor	low
4,5,6,7-tetrachlorophthalide	gamma-lactone; organic heterobicyclic compound; propan-1-ol; tetrachlorobenzene	antifungal agrochemical; melanin synthesis inhibitor	low
iprodione	benzenes; dichlorophenyl dicarboximide fungicide; imidazole fungicide; imidazolidine-2,4-dione; ureas	antifungal agrochemical; nematicide	low
bupirimate	aminopyrimidine; pyrimidine fungicide; secondary amino compound; sulfamate ester	androgen antagonist; antifungal agrochemical	low
tricyclazole	triazolobenzothiazole	antifungal agrochemical; melanin synthesis inhibitor	low
isoprothiolane	dithiolanes; isopropyl ester; malonate ester	antifungal agrochemical; environmental contaminant; insecticide; phospholipid biosynthesis inhibitor	low
triadimenol	aromatic ether; conazole fungicide; hemiaminal ether; monochlorobenzenes; secondary alcohol; triazole fungicide	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; xenobiotic metabolite	low
azaconazole	conazole fungicide; cyclic ketal; dichlorobenzene; dioxolane; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor	low
propiconazole	conazole fungicide; cyclic ketal; dichlorobenzene; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; environmental contaminant; xenobiotic	low
3-iodo-2-propynylbutylcarbamate	acetylenic compound; carbamate ester; carbamate fungicide; organoiodine compound	antifungal agrochemical; environmental contaminant; xenobiotic	low
prochloraz	amide fungicide; aromatic ether; conazole fungicide; imidazole fungicide; imidazoles; trichlorobenzene; ureas	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; environmental contaminant; xenobiotic	low
flusilazole	conazole fungicide; monofluorobenzenes; organosilicon compound; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; environmental contaminant; xenobiotic	low
spiroxamine	dioxolane; spiroketal; tertiary amino compound	antifungal agrochemical; environmental contaminant; sterol biosynthesis inhibitor; xenobiotic	low
difenoconazole	aromatic ether; conazole fungicide; cyclic ketal; dioxolane; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; environmental contaminant; xenobiotic	low
metconazole	conazole fungicide; cyclopentanols; monochlorobenzenes; tertiary alcohol; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor	low
mepanipyrim	acetylenic compound; aminopyrimidine; anilinopyrimidine fungicide; secondary amino compound	antifungal agrochemical; aryl hydrocarbon receptor agonist; hepatotoxic agent	low
dimethomorph	mixture; morpholine fungicide	antifungal agrochemical; environmental contaminant; xenobiotic	low
cyprodinil	aminopyrimidine; anilinopyrimidine fungicide; cyclopropanes; secondary amino compound	antifungal agrochemical; aryl hydrocarbon receptor agonist; environmental contaminant; xenobiotic	low
fludioxonil	benzodioxoles; nitrile; organofluorine compound; pyrroles	androgen antagonist; antifungal agrochemical; estrogen receptor agonist	low
s-methyl benzo(1,2,3)thiadiazole-7-carbothioate	benzothiadiazole; thioester	antifungal agrochemical; plant activator; profungicide	low
fluquinconazole	conazole fungicide; dichlorobenzene; organofluorine compound; quinazolines; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor	low
oryzemate	1,2-benzisothiazole; aromatic ether; benzothiazole fungicide; sulfone	antifungal agrochemical; plant activator	low
pyrimethanil	aminopyrimidine; anilinopyrimidine fungicide; secondary amino compound	antifungal agrochemical; aryl hydrocarbon receptor agonist; environmental contaminant; xenobiotic	low
tolclofos-methyl	dichlorobenzene; organic thiophosphate	antifungal agrochemical	low
pencycuron	monochlorobenzenes; phenylureas	antifungal agrochemical	low
fenpiclonil	dichlorobenzene; nitrile; pyrroles	antifungal agrochemical	low
fluazinam	(trifluoromethyl)benzenes; aminopyridine; C-nitro compound; chloropyridine; monochlorobenzenes; secondary amino compound	allergen; antifungal agrochemical; apoptosis inducer; environmental contaminant; xenobiotic	low
diethofencarb	aromatic ether; carbamate ester; carbanilate fungicide	antifungal agrochemical	low
carpropamid	amide fungicide; cyclopropylcarboxamide; monochlorobenzenes	antifungal agrochemical; EC 4.2.1.94 (scytalone dehydratase) inhibitor; melanin synthesis inhibitor; xenobiotic	low
n-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide	anilide fungicide; aromatic amide; dichlorobenzene; monocarboxylic acid amide; phenols	antifungal agrochemical; EC 1.14.13.72 (methylsterol monooxygenase) inhibitor; sterol biosynthesis inhibitor	low
validamycin a	antibiotic fungicide; polyol; secondary amino compound; validamycins	antifungal agrochemical; EC 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitor; EC 2.4.1.64 (alpha,alpha-trehalose phosphorylase) inhibitor; EC 3.2.1.28 (alpha,alpha-trehalase) inhibitor	low
potassium bicarbonate	organic salt; potassium salt	antifungal agrochemical; buffer; food acidity regulator; raising agent	low
n-(3-chloro-4-methylphenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide	anilide fungicide; monocarboxylic acid amide; monochlorobenzenes; organosulfur compound; thiadiazoles	antifungal agrochemical	low
zineb	dithiocarbamate salt; macromolecule; zinc coordination entity	antifungal agrochemical	low
nabam	dithiocarbamate salt; organic sodium salt	antifungal agrochemical	low
thiophanate	benzimidazole precursor fungicide; carbamate ester; carbamate fungicide; thioureas	antifungal agrochemical	low
azoxystrobin	aryloxypyrimidine; enoate ester; enol ether; methoxyacrylate strobilurin antifungal agent; methyl ester; nitrile	antifungal agrochemical; environmental contaminant; mitochondrial cytochrome-bc1 complex inhibitor; quinone outside inhibitor; xenobiotic	low
quinoxyfen	aromatic ether; monofluorobenzenes; organochlorine compound; quinolines	antifungal agrochemical	low
natamycin	antibiotic antifungal drug; dicarboxylic acid monoester; epoxide; macrolide antibiotic; monosaccharide derivative; polyene antibiotic	antifungal agrochemical; antimicrobial food preservative; apoptosis inducer; bacterial metabolite; ophthalmology drug	low
zinc dibutyldithiocarbamate	dithiocarbamate salt; zinc molecular entity	antifungal agrochemical	low
propineb	dithiocarbamate salt; macromolecule; zinc coordination entity	antifungal agrochemical	low
kresoxim-methyl	aromatic ether; methoxyiminoacetate strobilurin antifungal agent; methyl ester; oxime O-ether	antifungal agrochemical; environmental contaminant; mitochondrial cytochrome-bc1 complex inhibitor; xenobiotic	low
pyrachlostrobin	aromatic ether; carbamate ester; carbanilate fungicide; methoxycarbanilate strobilurin antifungal agent; monochlorobenzenes; pyrazoles	antifungal agrochemical; environmental contaminant; mitochondrial cytochrome-bc1 complex inhibitor; xenobiotic	low
uniconazole-p	(1E)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol; conazole fungicide; triazole fungicide	antifungal agrochemical; EC 1.14.13.78 (ent-kaurene oxidase) inhibitor; plant growth retardant	low
metrafenone	aromatic ether; aryl phenyl ketone fungicide; benzophenones; organobromine compound	antifungal agrochemical	low
cyazofamid	imidazole fungicide; imidazoles; nitrile; organochlorine compound; sulfamides; sulfonamide fungicide	antifungal agrochemical; mitochondrial cytochrome-bc1 complex inhibitor	low
fenamidone	carbohydrazide; imidazole fungicide; imidazolone; organic sulfide	antifungal agrochemical; mitochondrial cytochrome-bc1 complex inhibitor; quinone outside inhibitor	low
fluoxastrobin	aromatic ether; dioxazine; monochlorobenzenes; organofluorine compound; oxime O-ether; pyrimidines; strobilurin antifungal agent	antifungal agrochemical; mitochondrial cytochrome-bc1 complex inhibitor	low
fluopicolide	benzamide fungicide; benzamides; dichlorobenzene; monochloropyridine; organofluorine compound	antifungal agrochemical	low
picoxystrobin	aromatic ether; enoate ester; enol ether; methoxyacrylate strobilurin antifungal agent; organofluorine compound; pyridines	antifungal agrochemical; mitochondrial cytochrome-bc1 complex inhibitor	low
trifloxystrobin	methoxyiminoacetate strobilurin antifungal agent; methyl ester; organofluorine compound; oxime O-ether	antifungal agrochemical; mitochondrial cytochrome-bc1 complex inhibitor	low
ametoctradin	aromatic amine; triazolopyrimidines	antifungal agrochemical; mitochondrial cytochrome-bc1 complex inhibitor	low
phentin acetate	acetate ester; organotin compound	antifungal agrochemical	low
ethirimol	aminopyrimidine; pyrimidine fungicide; pyrimidone; secondary amino compound	antifungal agrochemical	low

Substance	Classes	Roles	Relationship Strength
carboxin	anilide fungicide; anilide; enamide; organosulfur heterocyclic compound; oxacycle; secondary carboxamide	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	low
oxycarboxin	anilide fungicide; anilide; organosulfur heterocyclic compound; oxacycle; sulfone	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	low
thifluzamide	1,3-thiazoles; anilide fungicide; aromatic amide; aromatic ether; dibromobenzene; organofluorine compound	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	low
2-chloro-n-(4-chlorobiphenyl-2-yl)nicotinamide	anilide fungicide; biphenyls; monochlorobenzenes; pyridinecarboxamide	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor; environmental contaminant; xenobiotic	low
tolfenpyrad	aromatic amide; aromatic ether; organochlorine compound; pyrazole insecticide	agrochemical; antifungal agent; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor; mitochondrial NADH:ubiquinone reductase inhibitor	low
diphenyl	aromatic fungicide; benzenes; biphenyls	antifungal agrochemical; antimicrobial food preservative	low
benomyl	aromatic amide; benzimidazole fungicide; benzimidazoles; benzimidazolylcarbamate fungicide; carbamate ester	acaricide; anthelminthic drug; antifungal agrochemical; microtubule-destabilising agent; tubulin modulator	low
n-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide	anilide fungicide; aromatic amide; dichlorobenzene; monocarboxylic acid amide; phenols	antifungal agrochemical; EC 1.14.13.72 (methylsterol monooxygenase) inhibitor; sterol biosynthesis inhibitor	low
n-(3-chloro-4-methylphenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide	anilide fungicide; monocarboxylic acid amide; monochlorobenzenes; organosulfur compound; thiadiazoles	antifungal agrochemical	low
pyrachlostrobin	aromatic ether; carbamate ester; carbanilate fungicide; methoxycarbanilate strobilurin antifungal agent; monochlorobenzenes; pyrazoles	antifungal agrochemical; environmental contaminant; mitochondrial cytochrome-bc1 complex inhibitor; xenobiotic	low

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	2010's	post-2020
niacinamide	4	pyridine alkaloid; pyridinecarboxamide; vitamin B3	anti-inflammatory agent; antioxidant; cofactor; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; Escherichia coli metabolite; geroprotector; human urinary metabolite; metabolite; mouse metabolite; neuroprotective agent; Saccharomyces cerevisiae metabolite; Sir2 inhibitor	2018	2021	4.5	medium	2	2
pyrazole	1	pyrazole		2020	2020	4.0	low	1	0
diphenyl	1	aromatic fungicide; benzenes; biphenyls	antifungal agrochemical; antimicrobial food preservative	2022	2022	2.0	low	0	1
thiophenes	3	mancude organic heteromonocyclic parent; monocyclic heteroarene; thiophenes; volatile organic compound	non-polar solvent	2018	2021	4.7	low	2	1
thiazoles	1	1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene		2021	2021	3.0	low	0	1
phenyl acetate	1	benzenes; phenyl acetates		2018	2018	6.0	low	1	0
flutolanil	1	(trifluoromethyl)benzenes; aromatic ether; benzamides; benzanilide fungicide	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	2021	2021	3.0	low	0	1
triazoles	3	1,2,3-triazole		2016	2022	5.3	low	2	1
difenoconazole	2	aromatic ether; conazole fungicide; cyclic ketal; dioxolane; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; environmental contaminant; xenobiotic	2016	2022	5.0	low	1	1
thifluzamide	1	1,3-thiazoles; anilide fungicide; aromatic amide; aromatic ether; dibromobenzene; organofluorine compound	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor	2021	2021	3.0	low	0	1
azoxystrobin	1	aryloxypyrimidine; enoate ester; enol ether; methoxyacrylate strobilurin antifungal agent; methyl ester; nitrile	antifungal agrochemical; environmental contaminant; mitochondrial cytochrome-bc1 complex inhibitor; quinone outside inhibitor; xenobiotic	2022	2022	2.0	low	0	1
sulfur	1	chalcogen; nonmetal atom	macronutrient	2021	2021	3.0	low	0	1
pyrachlostrobin	4	aromatic ether; carbamate ester; carbanilate fungicide; methoxycarbanilate strobilurin antifungal agent; monochlorobenzenes; pyrazoles	antifungal agrochemical; environmental contaminant; mitochondrial cytochrome-bc1 complex inhibitor; xenobiotic	2018	2023	3.0	medium	1	3
triticonazole	1			2023	2023	1.0	low	0	1
prothioconazole	1	cyclopropanes; monochlorobenzenes; tertiary alcohol; thiocarbonyl compound; triazoles		2018	2018	6.0	low	1	0
penthiopyrad	3	aromatic amide; organofluorine compound; pyrazoles; thiophenes		2018	2021	4.7	medium	2	1
5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]pyrazole-4-carboxamide	1	aromatic amide; organofluorine compound; pyrazoles		2016	2016	8.0	medium	1	0
n-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1h-pyrazole-4-carboxamide	1	aromatic amide; cyclopropanes; organofluorine compound; pyrazoles; ring assembly		2021	2021	3.0	medium	0	1
granite	1	triazolopyrimidines		2023	2023	1.0	low	0	1
sulfoxaflor	1	nitrile; organofluorine compound; pyridines; sulfoximide		2021	2021	3.0	low	0	1
trifloxystrobin	1			2018	2018	6.0	low	1	0

Condition	Studies	First Year	Last Year	Average Age	Relationship Strength	2010's	post-2020
Abnormalities, Multiple	1	2021	2021	3.0	high	0	1
Encephalopathy, Toxic	1	2022	2022	2.0	high	0	1
Sensitivity and Specificity	1	2017	2017	7.0	high	1	0

Safety/Toxicity (2)

Article	Year
The adverse effects of fluxapyroxad on the neurodevelopment of zebrafish embryos. Chemosphere, , Volume: 307, Issue:Pt 1	2022
Toxic effects and potential mechanisms of Fluxapyroxad to zebrafish (Danio rerio) embryos. The Science of the total environment, , May-15, Volume: 769	2021

fluxapyroxad

Description

Cross-References

Synonyms (35)

Roles (2)

Drug Classes (5)

Research

Studies (33)

Study Types

Related Drugs (1,108)

Drugs in this Class (1,004)

Drugs with this Function (103)

Drugs in Same Class and Function (10)

Drugs Researched Together (21)

Related Conditions (3)

Safety/Toxicity (2)