Page last updated: 2024-08-07 10:34:53
Peroxiredoxin-like 2A
A peroxiredoxin-like 2A that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9BRX8]
Synonyms
Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes;
Protein PAMM;
Redox-regulatory protein FAM213A
Research
Bioassay Publications (1)
Timeframe | Studies on this Protein(%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Compounds (1)
Drugs with Inhibition Measurements
Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
---|---|---|---|---|---|
pci 32765 | Homo sapiens (human) | IC50 | 0.9000 | 1 | 1 |
Enables
This protein enables 1 target(s):
Target | Category | Definition |
---|---|---|
antioxidant activity | molecular function | Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage. [ISBN:0198506732] |
Located In
This protein is located in 2 target(s):
Target | Category | Definition |
---|---|---|
extracellular region | cellular component | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators] |
cytoplasm | cellular component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
Active In
This protein is active in 1 target(s):
Target | Category | Definition |
---|---|---|
cytoplasm | cellular component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
Involved In
This protein is involved in 2 target(s):
Target | Category | Definition |
---|---|---|
regulation of osteoclast differentiation | biological process | Any process that modulates the frequency, rate or extent of osteoclast differentiation. [GOC:go_curators] |
cellular oxidant detoxification | biological process | Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide. [GOC:dos, GOC:vw] |