Page last updated: 2024-08-07 10:34:53

Peroxiredoxin-like 2A

A peroxiredoxin-like 2A that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9BRX8]

Synonyms

Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes;
Protein PAMM;
Redox-regulatory protein FAM213A

Research

Bioassay Publications (1)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Compounds (1)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
pci 32765Homo sapiens (human)IC500.900011

Enables

This protein enables 1 target(s):

TargetCategoryDefinition
antioxidant activitymolecular functionInhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage. [ISBN:0198506732]

Located In

This protein is located in 2 target(s):

TargetCategoryDefinition
extracellular regioncellular componentThe space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. [GOC:go_curators]
cytoplasmcellular componentThe contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]

Active In

This protein is active in 1 target(s):

TargetCategoryDefinition
cytoplasmcellular componentThe contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]

Involved In

This protein is involved in 2 target(s):

TargetCategoryDefinition
regulation of osteoclast differentiationbiological processAny process that modulates the frequency, rate or extent of osteoclast differentiation. [GOC:go_curators]
cellular oxidant detoxificationbiological processAny process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide. [GOC:dos, GOC:vw]