Page last updated: 2024-08-07 13:19:24
Melatonin receptor type 1A
A melatonin receptor type 1A that is encoded in the genome of chicken. [OMA:P49285, PRO:DNx]
Synonyms
Mel-1A-R;
Mel1a receptor;
CKA
Research
Bioassay Publications (8)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
Compounds (13)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| melatonin | Gallus gallus (chicken) | Ki | 0.0007 | 7 | 8 |
| n-acetyltryptamine | Gallus gallus (chicken) | Ki | 0.4898 | 1 | 1 |
| N-Acetylhomoveratrylamine | Gallus gallus (chicken) | Ki | 0.8700 | 1 | 1 |
| s20098 | Gallus gallus (chicken) | Ki | 0.0005 | 3 | 3 |
| 2-iodomelatonin | Gallus gallus (chicken) | Ki | 0.0000 | 1 | 1 |
| s 20928 | Gallus gallus (chicken) | Ki | 0.7870 | 1 | 1 |
| n-cyclopropylcarbonyl-2-(7-methoxy-1-naphthyl)ethylamine | Gallus gallus (chicken) | Ki | 0.0195 | 1 | 1 |
| prinomastat | Gallus gallus (chicken) | IC50 | 0.0049 | 1 | 1 |
| N-[2-(4-methoxyphenyl)ethyl]acetamide | Gallus gallus (chicken) | Ki | 50.5000 | 2 | 2 |
| ah 001 | Gallus gallus (chicken) | Ki | 0.1251 | 2 | 2 |
| pnu 142372 | Gallus gallus (chicken) | Ki | 0.0180 | 1 | 2 |
| pnu 107859 | Gallus gallus (chicken) | Ki | 0.7100 | 1 | 2 |
| n-acetyl-4-aminomethyl-6-methoxy-9-methyl-1,2,3,4-tetrahydrocarbazole | Gallus gallus (chicken) | Ki | 0.0010 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| melatonin | Gallus gallus (chicken) | EC50 | 0.0226 | 1 | 1 |
| s20098 | Gallus gallus (chicken) | EC50 | 0.0101 | 1 | 1 |
| s 20928 | Gallus gallus (chicken) | EC50 | 1.0000 | 1 | 1 |