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Melatonin receptor type 1A
A melatonin receptor type 1A that is encoded in the genome of chicken. [OMA:P49285, PRO:DNx]
Synonyms
Mel-1A-R;
Mel1a receptor;
CKA
Research
Bioassay Publications (8)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
Compounds (13)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| melatonin | Gallus gallus (chicken) | EC50 | 0.0226 | 1 | 1 |
| s20098 | Gallus gallus (chicken) | EC50 | 0.0101 | 1 | 1 |
| s 20928 | Gallus gallus (chicken) | EC50 | 1.0000 | 1 | 1 |
Indole-based melatonin analogues: Synthetic approaches and biological activity.European journal of medicinal chemistry, , Jan-01, Volume: 185, 2020
Synthesis of phenalene and acenaphthene derivatives as new conformationally restricted ligands for melatonin receptors.Journal of medicinal chemistry, , Nov-02, Volume: 43, Issue:22, 2000
Melatonergic properties of the (+)- and (-)-enantiomers of N-(4-methoxy-2,3-dihydro-1H-phenalen-2-yl)amide derivatives.Journal of medicinal chemistry, , Mar-25, Volume: 42, Issue:6, 1999
Three-dimensional quantitative structure-activity relationship of melatonin receptor ligands: a comparative molecular field analysis study.Journal of medicinal chemistry, , Feb-28, Volume: 40, Issue:5, 1997
Mapping the melatonin receptor. 4. Comparison of the binding affinities of a series of substituted phenylalkyl amides.Journal of medicinal chemistry, , Apr-26, Volume: 39, Issue:9, 1996
Design and synthesis of new naphthalenic derivatives as ligands for 2-[125I]iodomelatonin binding sites.Journal of medicinal chemistry, , Jun-09, Volume: 38, Issue:12, 1995
Synthesis of phenalene and acenaphthene derivatives as new conformationally restricted ligands for melatonin receptors.Journal of medicinal chemistry, , Nov-02, Volume: 43, Issue:22, 2000
Melatonergic properties of the (+)- and (-)-enantiomers of N-(4-methoxy-2,3-dihydro-1H-phenalen-2-yl)amide derivatives.Journal of medicinal chemistry, , Mar-25, Volume: 42, Issue:6, 1999
Three-dimensional quantitative structure-activity relationship of melatonin receptor ligands: a comparative molecular field analysis study.Journal of medicinal chemistry, , Feb-28, Volume: 40, Issue:5, 1997
Three-dimensional quantitative structure-activity relationship of melatonin receptor ligands: a comparative molecular field analysis study.Journal of medicinal chemistry, , Feb-28, Volume: 40, Issue:5, 1997
Mapping the melatonin receptor. 4. Comparison of the binding affinities of a series of substituted phenylalkyl amides.Journal of medicinal chemistry, , Apr-26, Volume: 39, Issue:9, 1996