Condition | Indicated | Relationship Strength | Studies | Trials |
Glioblastoma with Sarcomatous Component [description not available] | 0 | 2.45 | 2 | 0 |
Benign Neoplasms, Brain [description not available] | 0 | 6.94 | 17 | 0 |
Brain Neoplasms Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 6.94 | 17 | 0 |
Gliosarcoma Rare mixed tumors of the brain and rarely the spinal cord which contain malignant neuroectodermal (glial) and mesenchymal components, including spindle-shaped fibrosarcoma cells. These tumors are highly aggressive and present primarily in adults as rapidly expanding mass lesions. They may arise in tissue that has been previously irradiated. (From Br J Neurosurg 1995 Apr;9(2):171-8) | 0 | 2.45 | 2 | 0 |
Recrudescence [description not available] | 0 | 9.33 | 18 | 5 |
Cancer of Prostate [description not available] | 0 | 20.04 | 179 | 53 |
Prostatic Neoplasms Tumors or cancer of the PROSTATE. | 0 | 20.04 | 179 | 53 |
Cystadenoma, Serous A cystic tumor of the ovary, containing thin, clear, yellow serous fluid and varying amounts of solid tissue, with a malignant potential several times greater than that of mucinous cystadenoma (CYSTADENOMA, MUCINOUS). It can be unilocular, parvilocular, or multilocular. It is often bilateral and papillary. The cysts may vary greatly in size. (Dorland, 27th ed; from Hughes, Obstetric-Gynecologic Terminology, 1972) | 0 | 2.31 | 1 | 0 |
Breast Cancer [description not available] | 0 | 7.23 | 6 | 2 |
Breast Neoplasms Tumors or cancer of the human BREAST. | 0 | 7.23 | 6 | 2 |
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 11.87 | 21 | 5 |
Carcinoma, Thymic [description not available] | 0 | 2.76 | 2 | 0 |
Cancer of the Thymus [description not available] | 0 | 2.76 | 2 | 0 |
Local Neoplasm Recurrence [description not available] | 0 | 18.57 | 98 | 44 |
Thymoma A neoplasm originating from thymic tissue, usually benign, and frequently encapsulated. Although it is occasionally invasive, metastases are extremely rare. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (previously termed granulomatous thymoma), should not be regarded as thymoma. (From Stedman, 25th ed) | 0 | 2.76 | 2 | 0 |
Thymus Neoplasms Tumors or cancer of the THYMUS GLAND. | 0 | 2.76 | 2 | 0 |
ER-Negative PR-Negative HER2-Negative Breast Cancer [description not available] | 0 | 2.6 | 1 | 0 |
Triple Negative Breast Neoplasms Breast neoplasms that do not express ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and do not overexpress the NEU RECEPTOR/HER-2 PROTO-ONCOGENE PROTEIN. | 0 | 2.6 | 1 | 0 |
Lung Adenocarcinoma [description not available] | 0 | 2.98 | 3 | 0 |
Coin Lesion, Pulmonary [description not available] | 0 | 2.41 | 1 | 0 |
Cancer of Lung [description not available] | 0 | 4.87 | 2 | 1 |
Adenocarcinoma of Lung A carcinoma originating in the lung and the most common lung cancer type in never-smokers. Malignant cells exhibit distinct features such as glandular epithelial, or tubular morphology. Mutations in KRAS, EGFR, BRAF, and ERBB2 genes are associated with this cancer. | 0 | 2.98 | 3 | 0 |
Lung Neoplasms Tumors or cancer of the LUNG. | 0 | 4.87 | 2 | 1 |
Bone Cancer [description not available] | 0 | 12.83 | 23 | 6 |
Female Genital Neoplasms [description not available] | 0 | 2.6 | 1 | 0 |
Bone Neoplasms Tumors or cancer located in bone tissue or specific BONES. | 0 | 12.83 | 23 | 6 |
Genital Neoplasms, Female Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE). | 0 | 2.6 | 1 | 0 |
Hepatitis INFLAMMATION of the LIVER. | 0 | 2.6 | 1 | 0 |
Lymph Node Metastasis [description not available] | 0 | 12.22 | 20 | 7 |
Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply. | 0 | 2.6 | 1 | 0 |
Atherogenesis [description not available] | 0 | 2.21 | 1 | 0 |
Vascular Calcification Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS. | 0 | 2.21 | 1 | 0 |
Cardiovascular Stroke [description not available] | 0 | 2.21 | 1 | 0 |
Carotid Artery Narrowing [description not available] | 0 | 2.21 | 1 | 0 |
Aortic Diseases Pathological processes involving any part of the AORTA. | 0 | 2.21 | 1 | 0 |
Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). | 0 | 2.21 | 1 | 0 |
Carotid Stenosis Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3) | 0 | 2.21 | 1 | 0 |
Atherosclerosis A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. | 0 | 2.21 | 1 | 0 |
Disease Exacerbation [description not available] | 0 | 3.12 | 1 | 0 |
Metastase [description not available] | 0 | 7.75 | 15 | 0 |
Androgen-Independent Prostatic Cancer [description not available] | 0 | 4.18 | 5 | 0 |
Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 7.75 | 15 | 0 |
Prostatic Neoplasms, Castration-Resistant Tumors or cancer of the PROSTATE which can grow in the presence of low or residual amount of androgen hormones such as TESTOSTERONE. | 0 | 4.18 | 5 | 0 |
Adenoma, Basal Cell [description not available] | 0 | 2.25 | 1 | 0 |
Cancer of Pituitary [description not available] | 0 | 2.25 | 1 | 0 |
Adenoma A benign epithelial tumor with a glandular organization. | 0 | 2.25 | 1 | 0 |
Pituitary Neoplasms Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA. | 0 | 2.25 | 1 | 0 |
Multiple Primary Neoplasms [description not available] | 0 | 2.61 | 2 | 0 |
Atypical Lipomatous Tumor [description not available] | 0 | 2.25 | 1 | 0 |
Liposarcoma A malignant tumor derived from primitive or embryonal lipoblastic cells. It may be composed of well-differentiated fat cells or may be dedifferentiated: myxoid (LIPOSARCOMA, MYXOID), round-celled, or pleomorphic, usually in association with a rich network of capillaries. Recurrences are common and dedifferentiated liposarcomas metastasize to the lungs or serosal surfaces. (From Dorland, 27th ed; Stedman, 25th ed) | 0 | 2.25 | 1 | 0 |
Adenocarcinoma, Basal Cell [description not available] | 0 | 6.48 | 5 | 1 |
Adenocarcinoma A malignant epithelial tumor with a glandular organization. | 0 | 6.48 | 5 | 1 |
Adenolymphoma A benign tumor characterized histologically by tall columnar epithelium within a lymphoid tissue stroma. It is usually found in the salivary glands, especially the parotid. | 0 | 2.25 | 1 | 0 |
Cancer of Parotid [description not available] | 0 | 2.25 | 1 | 0 |
Parotid Neoplasms Tumors or cancer of the PAROTID GLAND. | 0 | 2.25 | 1 | 0 |
Cancer of Penis [description not available] | 0 | 2.93 | 3 | 0 |
Penile Neoplasms Cancers or tumors of the PENIS or of its component tissues. | 0 | 2.93 | 3 | 0 |
Carcinoma, Epidermoid [description not available] | 0 | 3.13 | 4 | 0 |
Cancer of Cervix [description not available] | 0 | 2.25 | 1 | 0 |
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) | 0 | 3.13 | 4 | 0 |
Uterine Cervical Neoplasms Tumors or cancer of the UTERINE CERVIX. | 0 | 2.25 | 1 | 0 |
Perforated Appendicitis [description not available] | 0 | 2.25 | 1 | 0 |
Acute Disease Disease having a short and relatively severe course. | 0 | 2.25 | 1 | 0 |
Appendicitis Acute inflammation of the APPENDIX. Acute appendicitis is classified as simple, gangrenous, or perforated. | 0 | 2.25 | 1 | 0 |
Ureterocele A cystic dilatation of the end of a URETER as it enters into the URINARY BLADDER. It is characterized by the ballooning of the ureteral orifice into the lumen of the bladder and may obstruct urine flow. | 0 | 2.31 | 1 | 0 |
Dysplastic Nevus Syndrome, Hereditary [description not available] | 0 | 2.31 | 1 | 0 |
Malignant Melanoma [description not available] | 0 | 2.61 | 2 | 0 |
Cancer of Skin [description not available] | 0 | 2.31 | 1 | 0 |
Melanoma A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) | 0 | 2.61 | 2 | 0 |
Skin Neoplasms Tumors or cancer of the SKIN. | 0 | 2.31 | 1 | 0 |
Anaplastic Oligodendroglioma [description not available] | 0 | 2.61 | 2 | 0 |
Oligodendroglioma A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655) | 0 | 2.61 | 2 | 0 |
Cancer of the Urinary Tract [description not available] | 0 | 2.31 | 1 | 0 |
Cancer of Liver [description not available] | 0 | 2.63 | 2 | 0 |
Liver Neoplasms Tumors or cancer of the LIVER. | 0 | 2.63 | 2 | 0 |
Neuroendocrine Tumors Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition. | 0 | 2.31 | 1 | 0 |
Gastrointestinal Stromal Neoplasm [description not available] | 0 | 2.31 | 1 | 0 |
Gastrointestinal Stromal Tumors All tumors in the GASTROINTESTINAL TRACT arising from mesenchymal cells (MESODERM) except those of smooth muscle cells (LEIOMYOMA) or Schwann cells (SCHWANNOMA). | 0 | 2.31 | 1 | 0 |
Desmoid [description not available] | 0 | 2.31 | 1 | 0 |
Fibromatosis, Aggressive A childhood counterpart of abdominal or extra-abdominal desmoid tumors, characterized by firm subcutaneous nodules that grow rapidly in any part of the body but do not metastasize. The adult form of abdominal fibromatosis is FIBROMATOSIS, ABDOMINAL. (Stedman, 25th ed) | 0 | 2.31 | 1 | 0 |
Angioblastic Meningioma [description not available] | 0 | 2.91 | 3 | 0 |
Meningioma A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7) | 0 | 2.91 | 3 | 0 |
Bladder Cancer [description not available] | 0 | 2.31 | 1 | 0 |
Carcinoma, Papillary A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (Stedman, 25th ed) | 0 | 2.31 | 1 | 0 |
Urinary Bladder Neoplasms Tumors or cancer of the URINARY BLADDER. | 0 | 2.31 | 1 | 0 |
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 2.55 | 2 | 0 |
Breast Cancer, Male [description not available] | 0 | 2.17 | 1 | 0 |
Breast Neoplasms, Male Any neoplasms of the male breast. These occur infrequently in males in developed countries, the incidence being about 1% of that in females. | 0 | 2.17 | 1 | 0 |
Pancreatic Diseases Pathological processes of the PANCREAS. | 0 | 2.17 | 1 | 0 |
Hepatocellular Carcinoma [description not available] | 0 | 2.17 | 1 | 0 |
Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. | 0 | 2.17 | 1 | 0 |
Benign Meningeal Neoplasms [description not available] | 0 | 2.59 | 2 | 0 |
Meningeal Neoplasms Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord. | 0 | 2.59 | 2 | 0 |
Argentaffinoma [description not available] | 0 | 2.21 | 1 | 0 |
Cancer of Intestines [description not available] | 0 | 2.21 | 1 | 0 |
Cancer of Rectum [description not available] | 0 | 2.21 | 1 | 0 |
Carcinoid Tumor A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182) | 0 | 2.21 | 1 | 0 |
Intestinal Neoplasms Tumors or cancer of the INTESTINES. | 0 | 2.21 | 1 | 0 |
Rectal Neoplasms Tumors or cancer of the RECTUM. | 0 | 2.21 | 1 | 0 |
Cancer of Oropharnyx [description not available] | 0 | 2.61 | 2 | 0 |
Oropharyngeal Neoplasms Tumors or cancer of the OROPHARYNX. | 0 | 2.61 | 2 | 0 |
Glial Cell Tumors [description not available] | 0 | 5.93 | 8 | 0 |
Glioma Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21) | 0 | 5.93 | 8 | 0 |
Minimal Disease, Residual [description not available] | 0 | 2.21 | 1 | 0 |
Osseous Paget's Disease [description not available] | 0 | 2.21 | 1 | 0 |
Osteitis Deformans A disease marked by repeated episodes of increased bone resorption followed by excessive attempts at repair, resulting in weakened, deformed bones of increased mass. The resultant architecture of the bone assumes a mosaic pattern in which the fibers take on a haphazard pattern instead of the normal parallel symmetry. | 0 | 2.21 | 1 | 0 |
Anemia, Cooley's [description not available] | 0 | 2.21 | 1 | 0 |
beta-Thalassemia A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent. | 0 | 2.21 | 1 | 0 |
Innate Inflammatory Response [description not available] | 0 | 5.32 | 5 | 0 |
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 5.32 | 5 | 0 |
Carcinoma, Anaplastic [description not available] | 0 | 11.35 | 16 | 16 |
Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer. | 0 | 11.35 | 16 | 16 |
Adenoma, Prostatic [description not available] | 0 | 2.1 | 1 | 0 |
Prostatic Hyperplasia Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both. | 0 | 2.1 | 1 | 0 |
Adenitis [description not available] | 0 | 2.1 | 1 | 0 |
Carcinoma, Ductal, Breast An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST. | 0 | 3.51 | 1 | 1 |
Invasiveness, Neoplasm [description not available] | 0 | 3.92 | 2 | 1 |
Carcinoma, Lobular A type of BREAST CANCER where the abnormal malignant cells form in the lobules, or milk-producing glands, of the breast. | 0 | 3.51 | 1 | 1 |
Chronic Illness [description not available] | 0 | 4.45 | 1 | 1 |
Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 4.45 | 1 | 1 |
Benign Neoplasms [description not available] | 0 | 2.01 | 1 | 0 |
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 2.01 | 1 | 0 |