Page last updated: 2024-12-07

benzothiazoline

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Benzothiazoline is a heterocyclic compound with a five-membered ring containing sulfur, nitrogen, and carbon atoms. It is a colorless liquid that is used as an intermediate in the synthesis of dyes, pharmaceuticals, and other chemicals. The synthesis of benzothiazoline typically involves the reaction of o-aminothiophenol with a carbonyl compound, such as an aldehyde or ketone. Benzothiazoline derivatives have been found to exhibit a range of biological activities, including antibacterial, antifungal, and anti-inflammatory properties. They are also used in the production of dyes, polymers, and pesticides. The study of benzothiazolines is important due to their versatility and potential applications in various fields. Researchers investigate their synthesis, properties, and biological activities to explore their potential in medicine, materials science, and other industries.'

Cross-References

ID SourceID
PubMed CID96588
SCHEMBL ID26747
MeSH IDM0163932

Synonyms (18)

Synonym
nsc-81218
benzothiazoline
4433-52-7
2,3-dihydrobenzothiazole
nsc81218
AKOS000282924
2,3-dihydro-1,3-benzothiazole
FT-0660763
A845203
t7b4556d2a ,
nsc 81218
unii-t7b4556d2a
benzothiazole, 2,3-dihydro-
CCG-40423
WOHLSTOWRAOMSG-UHFFFAOYSA-N
SCHEMBL26747
DTXSID30196142
benzo[d]thiazoline

Research Excerpts

Overview

Benzothiazoline is an efficient reducing agent for the chiral BINOL-phosphoric acid.

ExcerptReferenceRelevance
"Benzothiazoline is an efficient reducing agent for the chiral BINOL-phosphoric acid catalyzed enantioselective transfer hydrogenation of ketimines and α-imino esters to afford the corresponding amines with high enantioselectivities. "( DFT study of the mechanism and origin of enantioselectivity in chiral BINOL-phosphoric acid catalyzed transfer hydrogenation of ketimine and α-imino ester using benzothiazoline.
Shibata, Y; Yamanaka, M, 2013
)
2.03
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (29)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (20.69)29.6817
2010's18 (62.07)24.3611
2020's5 (17.24)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 49.65

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index49.65 (24.57)
Research Supply Index3.43 (2.92)
Research Growth Index5.01 (4.65)
Search Engine Demand Index76.15 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (49.65)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews3 (10.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other27 (90.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]