Butyrophilin subfamily 3 member A1

A butyrophilin subfamily 3 member A1 that is encoded in the genome of human. [PRO:WCB, UniProtKB:O00481]

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
3,3-dimethylallyl pyrophosphate	Homo sapiens (human)	IC50	270.0000	1	1
isopentenyl pyrophosphate	Homo sapiens (human)	IC50	513.0000	1	1
sodium pyrophosphate	Homo sapiens (human)	IC50	1,140.0000	1	1
(e)-4-hydroxy-3-methylbut-2-enyl diphosphate	Homo sapiens (human)	IC50	46.7000	10	10

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
3,3-dimethylallyl pyrophosphate	Homo sapiens (human)	EC50	1.5000	1	1
isopentenyl pyrophosphate	Homo sapiens (human)	EC50	36.0000	3	3
risedronic acid	Homo sapiens (human)	EC50	0.0800	1	1
zoledronic acid	Homo sapiens (human)	EC50	41.1093	5	5
(e)-4-hydroxy-3-methylbut-2-enyl diphosphate	Homo sapiens (human)	EC50	0.0009	8	8
(e)-4-hydroxy-3-methylbut-2-enyl diphosphate	Homo sapiens (human)	Kd	2.9050	2	2

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
zoledronic acid	Homo sapiens (human)	ED50	100.0000	1	1
(e)-4-hydroxy-3-methylbut-2-enyl diphosphate	Homo sapiens (human)	ED50	100.0000	1	1

This protein enables 2 target(s):

Target	Category	Definition
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
signaling receptor binding	molecular function	Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [GOC:bf, GOC:ceb, ISBN:0198506732]

This protein is located in 1 target(s):

Target	Category	Definition
plasma membrane	cellular component	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]

This protein is active in 1 target(s):

Target	Category	Definition
external side of plasma membrane	cellular component	The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface. [GOC:dos, GOC:tb]

This protein is involved in 6 target(s):

Target	Category	Definition
positive regulation of cytokine production	biological process	Any process that activates or increases the frequency, rate or extent of production of a cytokine. [GOC:add, ISBN:0781735149]
adaptive immune response	biological process	An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). [GO_REF:0000022, GOC:add, ISBN:0781735149]
positive regulation of type II interferon production	biological process	Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon. [GOC:add, GOC:mah, PMID:15546383]
activated T cell proliferation	biological process	The expansion of a T cell population following activation by an antigenic stimulus. [GOC:add, GOC:dph]
T cell receptor signaling pathway	biological process	The series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. [GOC:add]
regulation of cytokine production	biological process	Any process that modulates the frequency, rate, or extent of production of a cytokine. [GOC:add, ISBN:0781735149]