Page last updated: 2024-08-07 14:53:49
Capsid protein
[no definition available]
Synonyms
Research
Bioassay Publications (5)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
Compounds (6)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| lamivudine | Hepatitis B virus | IC50 | 50.0500 | 2 | 2 |
| bay 41-4109 | Hepatitis B virus | IC50 | 0.4300 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| adefovir | Hepatitis B virus | EC50 | 0.0827 | 1 | 1 |
| lamivudine | Hepatitis B virus | EC50 | 5.1850 | 2 | 2 |
| telbivudine | Hepatitis B virus | EC50 | 0.8194 | 1 | 1 |
| tenofovir | Hepatitis B virus | EC50 | 0.2415 | 1 | 1 |
| bay 41-4109 | Hepatitis B virus | EC50 | 0.0480 | 1 | 1 |
| entecavir | Hepatitis B virus | EC50 | 5.0001 | 2 | 2 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| bay 41-4109 | Hepatitis B virus | EC90 | 0.1020 | 1 | 1 |
Design, synthesis and evaluation of heteroaryldihydropyrimidine analogues bearing spiro ring as hepatitis B virus capsid protein inhibitors.European journal of medicinal chemistry, , Dec-05, Volume: 225, 2021
Assessment of quinazolinone derivatives as novel non-nucleoside hepatitis B virus inhibitors.European journal of medicinal chemistry, , Aug-15, Volume: 176, 2019
Synthesis of sulfamoylbenzamide derivatives as HBV capsid assembly effector.European journal of medicinal chemistry, , Sep-29, Volume: 138, 2017
Discovery of hepatitis B virus capsid assembly inhibitors leading to a heteroaryldihydropyrimidine based clinical candidate (GLS4).Bioorganic & medicinal chemistry, , 02-01, Volume: 25, Issue:3, 2017
[no title available]ACS medicinal chemistry letters, , Sep-14, Volume: 8, Issue:9, 2017