Retina-specific copper amine oxidase

A retina-specific copper amine oxidase that is encoded in the genome of human. [PRO:DNx, UniProtKB:O75106]

RAO;
EC 1.4.3.21;
Amine oxidase [copper-containing];
Semicarbazide-sensitive amine oxidase;
SSAO

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
rolipram	Homo sapiens (human)	IC50	0.0003	1	1
mofegiline	Homo sapiens (human)	IC50	0.0100	1	1
zaprinast	Homo sapiens (human)	IC50	160.0000	1	1

This protein enables 6 target(s):

Target	Category	Definition
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
primary amine oxidase activity	molecular function	Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide. [EC:1.4.3.21]
electron transfer activity	molecular function	A molecular function representing the directed movement of electrons from one molecular entity to another, typically mediated by electron carriers or acceptors, resulting in the transfer of energy and/or the reduction-oxidation (redox) transformation of chemical species. This activity is fundamental to various biological processes, including cellular respiration and photosynthesis, as well as numerous enzymatic reactions involved in metabolic pathways. [Wikipedia:Electron_transfer]
quinone binding	molecular function	Binding to a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds. [ISBN:0198506732]
aliphatic amine oxidase activity	molecular function	Catalysis of the reaction: an aliphatic amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide + H+. [MetaCyc:AMINEOXID-RXN]
copper ion binding	molecular function	Binding to a copper (Cu) ion. [GOC:ai]

This protein is located in 2 target(s):

Target	Category	Definition
cytoplasm	cellular component	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
plasma membrane	cellular component	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]

This protein is active in 1 target(s):

Target	Category	Definition
plasma membrane	cellular component	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]

This protein is involved in 4 target(s):

Target	Category	Definition
catecholamine metabolic process	biological process	The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. [GOC:jl, ISBN:0198506732]
xenobiotic metabolic process	biological process	The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:cab2, GOC:krc]
visual perception	biological process	The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image. [GOC:ai]
amine metabolic process	biological process	The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. [GOC:jl, ISBN:0198506732]