Page last updated: 2024-08-07 13:50:19
Gamma-aminobutyric acid type B receptor subunit 1
A gamma-aminobutyric acid type B receptor subunit 1 that is encoded in the genome of rat. [OMA:Q9Z0U4, PRO:DNx]
Synonyms
GABA-B receptor 1;
GABA-B-R1;
GABA-BR1;
GABABR1;
Gb1
Research
Bioassay Publications (7)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (13)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| gamma-aminobutyric acid | Rattus norvegicus (Norway rat) | IC50 | 0.0292 | 4 | 4 |
| baclofen | Rattus norvegicus (Norway rat) | IC50 | 0.2762 | 4 | 6 |
| gaboxadol | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| isoguvacine | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| sk&f 97541 | Rattus norvegicus (Norway rat) | IC50 | 0.0107 | 2 | 3 |
| Arbaclofen | Rattus norvegicus (Norway rat) | IC50 | 0.0860 | 2 | 2 |
| 3-aminopropylphosphonic acid | Rattus norvegicus (Norway rat) | IC50 | 6.8100 | 1 | 2 |
| cgp 35348 | Rattus norvegicus (Norway rat) | IC50 | 27.0000 | 1 | 2 |
| 5-(4-piperidyl)isoxazol-3-ol | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| 4-amino-3-(5-chloro-2-thienyl)butyric acid | Rattus norvegicus (Norway rat) | IC50 | 0.6100 | 1 | 1 |
| cgp 36742 | Rattus norvegicus (Norway rat) | IC50 | 38.0000 | 1 | 2 |
| cgp 46381 | Rattus norvegicus (Norway rat) | IC50 | 4.0000 | 1 | 2 |
| 3-aminopropylphosphinic acid | Rattus norvegicus (Norway rat) | IC50 | 0.0051 | 2 | 3 |