Compounds > methacycline
Page last updated: 2024-09-23

methacycline

Description

Methacycline: A broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

methacycline : A tetracycline that is the 6-methylene analogue of oxytetracycline, obtained by formal dehydration at position 6. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID66021
CHEBI ID173246
SCHEMBL ID77521
MeSH IDM0013539
PubMed CID54675785
CHEMBL ID249837
CHEBI ID6805
SCHEMBL ID4014
SCHEMBL ID4015
SCHEMBL ID19555132
MeSH IDM0013539

Synonyms (156)

Synonym
1,2-diacetylglycerol
1,2-diacetin
glycerol 1,2-diacetate
estol 1582
ai3-00676
brn 1775840
glycerine diacetate
einecs 246-941-2
acetin, 1,2-di-
glyceryl diacetate
estol 1583
2,3-diacetoxypropan-1-ol
glycerin diacetate
1,2,3-propanetriol, 1,2-diacetate
nsc 2348
(2-acetyloxy-3-hydroxypropyl) acetate
CHEBI:173246
acetin,2-di-
102-62-5
acetic acid, diglyceride
(hydroxymethyl)ethylene acetate
nsc2348
diacetyl glycerine
glycerol diacetate
2,3-diacetin
nsc-2348
wln: 1voy1q1ov1
1,3-propanetriol, 1,2-diacetate
1,2,3-propanetriol, diacetate
acetin, di-
1,2-diacylglycerol
AKOS006273209
9w955270zw ,
ccris 9462
3-02-00-00331 (beilstein handbook reference)
unii-9w955270zw
ccris 9354
gj0544w99q ,
unii-gj0544w99q
FT-0624585
SCHEMBL77521
2-(acetyloxy)-1-(hydroxymethyl)ethyl acetate
3-hydroxypropane-1,2-diyl diacetate
glyceryl 1,2-diacetate
1,2-diacetin, (+/-)-
1,2-diacetin, dl-
dl-1,2-diacetin
2-(acetyloxy)-1-(hydroxymethyl)ethyl acetate, aldrichcpr
(+/-)-glycerol 1,2-diacetate
dag 4:0
1-(acetyloxy)-3-hydroxypropan-2-yl acetate
(1-acetyloxy-3-hydroxypropan-2-yl)acetate
DTXSID70883105
3-hydroxypropane-1,2-diyldiacetate
Q24300357
A877596
CS-0236630
Z1198148277
EN300-1720881
AC-13213
ir235i7c5p ,
unii-ir235i7c5p
metaciclina
metacycline [inn]
AB00053593-03
KBIO1_000591
DIVK1C_000591
(4s,4ar,5s,5ar,12as)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methylidene-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
gs 2876
methacyclinum
bialatan
gs-2876
methacycline base
methacycline amphoteric
2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, (4s-(4alpha,4aalpha,5alpha,5aalpha,12aalpha))-
hsdb 3118
metacyclinum [inn-latin]
einecs 213-017-5
4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide
metaciclina [inn-spanish]
methacycline [usan:ban]
oxytetracycline, 6-methylene-
SPECTRUM_000381
PRESTWICK3_000964
BPBIO1_001065
BSPBIO_000967
NCGC00179358-01
methacycline (usan)
metacycline (inn)
SPECTRUM5_001576
D04972
(4s,4ar,5s,5ar,12as)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
AB00514707
metacycline
C07654
914-00-1
methacycline
6-deoxy-6-demethyl-6-methylene-5-oxytetracycline
DB00931
methylenecycline
tri-methacycline
6-demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline
6-methylene-5-hydroxytetracycline
6-methyleneoxytetracycline
6-methylene-5-oxytetracycline
KBIOSS_000861
KBIO2_000861
KBIO3_001894
KBIO2_005997
KBIOGR_001511
KBIO2_003429
SPECTRUM4_001016
SPBIO_001416
PRESTWICK0_000964
SPBIO_002888
NINDS_000591
PRESTWICK1_000964
SPECTRUM3_000917
SPECTRUM2_001398
PRESTWICK2_000964
IDI1_000591
motc
chebi:6805 ,
CHEMBL249837
ksc-12-231a
KUC106428N
metacyclinum
AKOS015961140
(4s,4ar,5s,5ar,12as)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
doxycycline hyclate impurity b [ep impurity]
doxycycline impurity b
2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, (4s-(4.alpha.,4a.alpha.,5.alpha.,5a.alpha.,12a.alpha.))-
methacycline [mi]
methacycline [usan]
methacycline [mart.]
doxycycline monohydrate impurity b [ep impurity]
metacycline [who-dd]
methacycline [vandf]
methacycline [hsdb]
SCHEMBL4014
SCHEMBL4015
MHIGBKBJSQVXNH-IWVLMIASSA-N
AB00053593_05
AB00053593_04
DTXSID2023272
bdbm50103629
SBI-0051637.P002
SCHEMBL19555132
NCGC00179358-03
NCGC00179358-05
BCP24961
Q2365033
2-naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, (4s,4ar,5s,5ar,12as)-
bdbm50565697
(4s,4ar,5s,5ar,12ar)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
EN300-7481364

Drug Classes (1)

ClassDescription
1,2-diglyceride
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (2)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Multidrug transporter MdfAEscherichia coli K-12IC50 (µMol)2.50002.50002.55002.6000AID71156
NAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)IC50 (µMol)3.60000.10003.38006.6000AID1742983
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (19)

Processvia Protein(s)Taxonomy
regulation of cellular pHMultidrug transporter MdfAEscherichia coli K-12
sodium ion transmembrane transportMultidrug transporter MdfAEscherichia coli K-12
response to antibioticMultidrug transporter MdfAEscherichia coli K-12
transmembrane transportMultidrug transporter MdfAEscherichia coli K-12
potassium ion transmembrane transportMultidrug transporter MdfAEscherichia coli K-12
proton transmembrane transportMultidrug transporter MdfAEscherichia coli K-12
xenobiotic detoxification by transmembrane export across the plasma membraneMultidrug transporter MdfAEscherichia coli K-12
protein deacetylationNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
protein deacetylationNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
mitochondrion organizationNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
regulation of ketone biosynthetic processNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
negative regulation of cardiac muscle cell apoptotic processNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
response to nutrient levelsNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
protein demalonylationNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
peptidyl-lysine demalonylationNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
protein desuccinylationNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
peptidyl-lysine desuccinylationNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
protein deglutarylationNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
negative regulation of reactive oxygen species metabolic processNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
epigenetic regulation of gene expressionNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (11)

Processvia Protein(s)Taxonomy
sodium:proton antiporter activityMultidrug transporter MdfAEscherichia coli K-12
potassium:proton antiporter activityMultidrug transporter MdfAEscherichia coli K-12
transmembrane transporter activityMultidrug transporter MdfAEscherichia coli K-12
NAD+ ADP-ribosyltransferase activityNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
NAD+-protein ADP-ribosyltransferase activityNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
zinc ion bindingNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
NAD-dependent protein lysine deacetylase activityNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
protein-malonyllysine demalonylase activityNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
protein-succinyllysine desuccinylase activityNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
protein-glutaryllysine deglutarylase activityNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
NAD+ bindingNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (7)

Processvia Protein(s)Taxonomy
plasma membraneMultidrug transporter MdfAEscherichia coli K-12
membraneMultidrug transporter MdfAEscherichia coli K-12
plasma membraneMultidrug transporter MdfAEscherichia coli K-12
nucleusNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
mitochondrionNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
mitochondrial intermembrane spaceNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
mitochondrial matrixNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
cytosolNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
mitochondrial matrixNAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (51)

Assay IDTitleYearJournalArticle
AID1347169Tertiary RLuc qRT-PCR qHTS assay for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1508630Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay2021Cell reports, 04-27, Volume: 35, Issue:4
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID1347156DAPI mCherry counterscreen qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347172Secondary qRT-PCR qHTS assay for selected Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347152Confirmatory screen NINDS AMC qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347168HepG2 cells viability qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347149Furin counterscreen qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347167Vero cells viability qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347163384 well plate NINDS AMC confirmatory qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347170Vero cells viability counterscreen for qRT-PCR qHTS assay of selected Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347154Primary screen GU AMC qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347158ZIKV-mCherry secondary qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347161Confirmatory screen NINDS Rhodamine qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347153Confirmatory screen GU AMC qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347171Orthogonal mCherry assay for qRT-PCR qHTS of selected Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1079941Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive disease, Budd-Chiari syndrome. Value is number of references indexed. [column 'VASC' in source]
AID311524Oral bioavailability in human2007Bioorganic & medicinal chemistry, Dec-15, Volume: 15, Issue:24
Hologram QSAR model for the prediction of human oral bioavailability.
AID1566494Inhibition of Escherichia coli RNase 3 dsRBD assessed as inhibition of pre-miRNA-21 maturation incubated for 0.5 to 1 hr2019ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5
Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition.
AID1079948Times to onset, minimal and maximal, observed in the indexed observations. [column 'DELAI' in source]
AID1566489Inhibition of biotinylated pre-let-7d microRNA (unknown origin) maturation preincubated for 15 mins followed by Pre-let-7d addition and measured after 5 hrs by cat-ELCCA2019ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5
Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition.
AID1079940Granulomatous liver disease, proven histopathologically. Value is number of references indexed. [column 'GRAN' in source]
AID1079946Presence of at least one case with successful reintroduction. [column 'REINT' in source]
AID1566487Binding affinity to biotinylated pre-let-7d microRNA (unknown origin) by SPR analysis2019ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5
Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition.
AID625294Drug Induced Liver Injury Prediction System (DILIps) validation dataset; compound DILI positive/negative as observed in O'Brien data2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID1079945Animal toxicity known. [column 'TOXIC' in source]
AID1079936Choleostatic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is < 2 (see ACUTE). Value is number of references indexed. [column 'CHOLE' in source]
AID1742983Inhibition of SIRT5 (unknown origin)2020European journal of medicinal chemistry, Nov-15, Volume: 206Identification of the subtype-selective Sirt5 inhibitor balsalazide through systematic SAR analysis and rationalization via theoretical investigations.
AID1566496Binding affinity to miR-21 RNA in human HeLA cells transfected with pmirGLO empty vector incubated for 48 hrs by Dual-Glo luciferase assay2019ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5
Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition.
AID1566497Binding affinity to miR-21 RNA in human HeLA cells transfected with pmir21 vector incubated for 48 hrs by Dual-Glo luciferase assay2019ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5
Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition.
AID1079935Cytolytic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is > 5 (see ACUTE). Value is number of references indexed. [column 'CYTOL' in source]
AID1079942Steatosis, proven histopathologically. Value is number of references indexed. [column 'STEAT' in source]
AID1079939Cirrhosis, proven histopathologically. Value is number of references indexed. [column 'CIRRH' in source]
AID1079931Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum activity 6 times the normal upper limit (N) or alkaline phosphatase serum activity of 1.7 N. Value is number of references indexed. [column 'BIOL' in source]
AID1566492Inhibition of Dicer mediated biotinylated pre-miRNA-21 (unknown origin) maturation in presence of 1;1 ratio of CaCl2 and MgCl2 preincubated for 15 mins followed by pre-miRNA-21 addition and measured after 5 hrs by cat-ELCCA2019ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5
Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition.
AID1566491Inhibition of Dicer mediated biotinylated pre-miRNA-21 (unknown origin) maturation in presence of 1 to 3 mM MgCl2 preincubated for 15 mins followed by pre-miRNA-21 addition and measured after 5 hrs by cat-ELCCA2019ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5
Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition.
AID1079944Benign tumor, proven histopathologically. Value is number of references indexed. [column 'T.BEN' in source]
AID1566488Inhibition of Dicer mediated biotinylated pre-miRNA-21 (unknown origin) maturation preincubated for 15 mins followed by pre-miRNA-21 addition and measured after 5 hrs by cat-ELCCA2019ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5
Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition.
AID1079938Chronic liver disease either proven histopathologically, or through a chonic elevation of serum amino-transferase activity after 6 months. Value is number of references indexed. [column 'CHRON' in source]
AID1079932Highest frequency of moderate liver toxicity observed during clinical trials, expressed as a percentage. [column '% BIOL' in source]
AID1079937Severe hepatitis, defined as possibly life-threatening liver failure or through clinical observations. Value is number of references indexed. [column 'MASS' in source]
AID1079933Acute liver toxicity defined via clinical observations and clear clinical-chemistry results: serum ALT or AST activity > 6 N or serum alkaline phosphatases activity > 1.7 N. This category includes cytolytic, choleostatic and mixed liver toxicity. Value is
AID1079943Malignant tumor, proven histopathologically. Value is number of references indexed. [column 'T.MAL' in source]
AID1079934Highest frequency of acute liver toxicity observed during clinical trials, expressed as a percentage. [column '% AIGUE' in source]
AID71156Inhibition of [3H]tetracycline uptake into everted membrane vesicles, prepared from tetracycline resistant Escherichia coli D1-2091993Journal of medicinal chemistry, Feb-05, Volume: 36, Issue:3
Inhibition of the tetracycline efflux antiport protein by 13-thio-substituted 5-hydroxy-6-deoxytetracyclines.
AID1079947Comments (NB not yet translated). [column 'COMMENTAIRES' in source]
AID1566486Binding affinity to biotinylated pre-miRNA-21 (unknown origin) by SPR analysis2019ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5
Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition.
AID1566490Inhibition of Dicer mediated biotinylated pre-miRNA-21 (unknown origin) maturation at 1 mM measured after 15 mins by cat-ELCCA relative to control2019ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5
Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition.
AID1079949Proposed mechanism(s) of liver damage. [column 'MEC' in source]
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
AID1347164384 well plate NINDS Rhodamine confirmatory qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1645848NCATS Kinetic Aqueous Solubility Profiling2019Bioorganic & medicinal chemistry, 07-15, Volume: 27, Issue:14
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (1,036)

TimeframeStudies, This Drug (%)All Drugs %
pre-1990404 (39.00)18.7374
1990's270 (26.06)18.2507
2000's122 (11.78)29.6817
2010's204 (19.69)24.3611
2020's36 (3.47)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials10 (1.37%)5.53%
Trials35 (10.06%)5.53%
Reviews81 (11.08%)6.00%
Reviews4 (1.15%)6.00%
Case Studies1 (0.14%)4.05%
Case Studies15 (4.31%)4.05%
Observational0 (0.00%)0.25%
Observational0 (0.00%)0.25%
Other639 (87.41%)84.16%
Other294 (84.48%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective Randomized Study to Compare Clinical Outcomes in Patients With Osteomyelitis Treated With Intravenous Antibiotics Versus Intravenous Antibiotics With an Early Switch to Oral Antibiotics[NCT02099240]Early Phase 111 participants (Actual)Interventional2014-03-06Terminated(stopped due to Not enough patient enrollment and lack of staffing)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
phorbols[no description available]medium60diterpene;
terpenoid fundamental parent
palmitic acid[no description available]medium120long-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor;
plant metabolite
oleic acid[no description available]medium110octadec-9-enoic acidantioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent
1-anilino-8-naphthalenesulfonate[no description available]medium140aminonaphthalene;
naphthalenesulfonic acid		fluorescent probe
natriuretic peptide, c-type[no description available]medium10
inositol-1,3,4,5-tetrakisphosphate[no description available]medium10inositol phosphate
triacetin[no description available]medium10triglycerideadjuvant;
antifungal drug;
food additive carrier;
food emulsifier;
food humectant;
fuel additive;
plant metabolite;
solvent
gamma-sitosterol[no description available]medium103beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
phytosterols		marine metabolite;
plant metabolite
cytellin[no description available]medium21
tristearin[no description available]medium20triacylglycerol 54:0Caenorhabditis elegans metabolite;
plant metabolite
2-methylpentane[no description available]medium10alkane
n-hexane[no description available]medium10alkane;
volatile organic compound		neurotoxin;
non-polar solvent
glycerol[no description available]medium140alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
1-palmitoyl-2-oleoylphosphatidylcholine[no description available]medium20
phosphatidylcholines[no description available]medium7711,2-diacyl-sn-glycero-3-phosphocholine
leupeptins[no description available]medium10
benzyloxycarbonylleucyl-leucyl-leucine aldehyde[no description available]medium10amino aldehyde;
carbamate ester;
tripeptide		proteasome inhibitor
acetyl coenzyme a[no description available]medium10acyl-CoAacyl donor;
coenzyme;
effector;
fundamental metabolite
alpha-linolenic acid[no description available]medium115linolenic acid;
omega-3 fatty acid		micronutrient;
mouse metabolite;
nutraceutical
tocopherols[no description available]medium10
d-alpha tocopherol[no description available]medium40alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite
plastochromanol 8[no description available]medium10
tocotrienols[no description available]medium10diterpenoid
glutamic acid[no description available]medium30glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
ucn 1028 c[no description available]medium40
glycolipids[no description available]medium210
glycerol 1-stearate[no description available]medium101-acylglycerol 18:0;
rac-1-monoacylglycerol		algal metabolite;
Caenorhabditis elegans metabolite
lithium[no description available]medium80alkali metal atom
valproic acid[no description available]medium20branched-chain fatty acid;
branched-chain saturated fatty acid		anticonvulsant;
antimanic drug;
EC 3.5.1.98 (histone deacetylase) inhibitor;
GABA agent;
neuroprotective agent;
psychotropic drug;
teratogenic agent
ethyl cellulose[no description available]medium10glycoside
cellulose[no description available]medium10glycoside
2,4,6-trimethyl-n-(meta-3-trifluoromethylphenyl)benzenesulfonamide[no description available]medium10sulfonamide
guanosine 5'-o-(3-thiotriphosphate)[no description available]medium110nucleoside triphosphate analogue
eicosapentaenoic acid[no description available]medium10icosapentaenoic acid;
omega-3 fatty acid		anticholesteremic drug;
antidepressant;
antineoplastic agent;
Daphnia galeata metabolite;
fungal metabolite;
micronutrient;
mouse metabolite;
nutraceutical
lysophosphatidic acid[no description available]medium301-acyl-sn-glycerol 3-phosphate
glycerylphosphorylcholine[no description available]medium10glycerophosphocholine
metformin[no description available]medium10guanidinesenvironmental contaminant;
geroprotector;
hypoglycemic agent;
xenobiotic
inositol 1,4,5-trisphosphate[no description available]medium780myo-inositol trisphosphatemouse metabolite
sodefrin[no description available]medium10
epidermal growth factor[no description available]medium150
vanadates[no description available]medium20trivalent inorganic anion;
vanadium oxoanion		EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
pervanadate[no description available]medium10
glycerophosphoinositol 4,5-bisphosphate[no description available]medium410
muramidase[no description available]medium10
1-butanol[no description available]medium60alkyl alcohol;
primary alcohol;
short-chain primary fatty alcohol		human metabolite;
mouse metabolite;
protic solvent
scutellarin[no description available]medium10glucosiduronic acid;
glycosyloxyflavone;
monosaccharide derivative;
trihydroxyflavone		antineoplastic agent;
proteasome inhibitor
thromboxane a2[no description available]medium30epoxy monocarboxylic acid;
thromboxanes A		mouse metabolite
thapsigargin[no description available]medium20butyrate ester;
organic heterotricyclic compound;
sesquiterpene lactone		calcium channel blocker;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor
indoleacetic acid[no description available]medium10indole-3-acetic acids;
monocarboxylic acid		auxin;
human metabolite;
mouse metabolite;
plant hormone;
plant metabolite
fluorouracil[no description available]medium10nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
ciprofloxacin[no description available]medium10aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic
arginine[no description available]medium30arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
r 59949[no description available]medium40diarylmethane
piperidines[no description available]medium40
sphingosine[no description available]medium100sphing-4-eninehuman metabolite;
mouse metabolite
sphingosine 1-phosphate[no description available]medium30sphingoid 1-phosphatemouse metabolite;
signalling molecule;
sphingosine-1-phosphate receptor agonist;
T-cell proliferation inhibitor;
vasodilator agent
niacinamide[no description available]medium11pyridine alkaloid;
pyridinecarboxamide;
vitamin B3		anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor
oxalic acid[no description available]medium11alpha,omega-dicarboxylic acidalgal metabolite;
human metabolite;
plant metabolite
caseins[no description available]medium30
g(m1) ganglioside[no description available]medium10alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine;
sialotetraosylceramide
interleukin-8[no description available]medium10
cdp ethanolamine[no description available]medium20nucleotide-(amino alcohol)s;
phosphoethanolamine		mouse metabolite
cytidine diphosphate[no description available]medium20cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-diphosphate		Escherichia coli metabolite;
mouse metabolite
phosphorylethanolamine[no description available]medium20phosphoethanolamine;
primary amino compound		algal metabolite;
human metabolite;
mouse metabolite
choline[no description available]medium200cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
aluminum[no description available]medium30boron group element atom;
elemental aluminium;
metal atom
benzyl alcohol[no description available]medium10benzyl alcoholsantioxidant;
fragrance;
metabolite;
solvent
4,4-difluoro-4-bora-3a,4a-diaza-s-indacene[no description available]medium10BODIPY compound
alanylphosphatidylglycerol[no description available]medium10
salicylic acid[no description available]medium10monohydroxybenzoic acidalgal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite
thyroxine[no description available]medium202-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine		antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone
guanosine triphosphate[no description available]medium90guanosine 5'-phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor
guanosine diphosphate[no description available]medium20guanosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor
naringenin[no description available]medium10(2S)-flavan-4-one;
naringenin		expectorant;
plant metabolite
glyceryl 2-arachidonate[no description available]medium102-acylglycerol 20:4;
endocannabinoid		human metabolite
phenyl acetate[no description available]medium20benzenes;
phenyl acetates
carbachol[no description available]medium150ammonium salt;
carbamate ester		cardiotonic drug;
miotic;
muscarinic agonist;
nicotinic acetylcholine receptor agonist;
non-narcotic analgesic
octadecane[no description available]medium10long-chain alkanebacterial metabolite;
plant metabolite
gold[no description available]medium10copper group element atom;
elemental gold
tretinoin[no description available]medium10retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule
arachidonic acid[no description available]medium390icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
alpha-glycerophosphoric acid[no description available]medium20glycerol monophosphatealgal metabolite;
human metabolite
cyclopropane[no description available]medium10cycloalkane;
cyclopropanes		inhalation anaesthetic
catechin[no description available]medium10catechinantioxidant;
plant metabolite
lipoamide[no description available]medium10dithiolanes;
monocarboxylic acid amide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
sinapinic acid[no description available]medium10sinapic acidMALDI matrix material;
plant metabolite
octanoic acid[no description available]medium10medium-chain fatty acid;
straight-chain saturated fatty acid		antibacterial agent;
Escherichia coli metabolite;
human metabolite
caprylates[no description available]medium10fatty acid anion 8:0;
straight-chain saturated fatty acid anion		human metabolite;
Saccharomyces cerevisiae metabolite
phorbol-12-myristate[no description available]medium10
prostratin[no description available]medium10
bryostatin 1[no description available]medium30
tyrosine[no description available]medium30amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
threonine[no description available]medium10amino acid zwitterion;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
threonine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
1,2-dioctanoylglycerol[no description available]medium80
capsaicin[no description available]medium10capsaicinoidnon-narcotic analgesic;
TRPV1 agonist;
voltage-gated sodium channel blocker
1-oleoyl-2-acetylglycerol[no description available]medium901,2-diglyceride
lactic acid[no description available]medium302-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
acetic acid[no description available]medium20monocarboxylic acidantimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one[no description available]medium30chromones;
morpholines;
organochlorine compound		autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector
cyclosporine[no description available]medium10
sodium fluoride[no description available]medium60fluoride saltmutagen
okadaic acid[no description available]medium50ketal
genistein[no description available]medium307-hydroxyisoflavonesantineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor
r 59022[no description available]medium80diarylmethane
1-stearoyl-2-arachidonoylglycerol[no description available]medium201,2-diglyceride
thiazoles[no description available]medium801,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
pyrimidinones[no description available]medium80
adenosine diphosphate[no description available]medium10adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite
ceramide 1-phosphate[no description available]medium10N-acylsphingosine 1-phosphate
1,6-bis(cyclohexyloximinocarbonyl)hexane[no description available]medium40carbamate ester;
organonitrogen compound
tiletamine hydrochloride[no description available]medium40
thymidine monophosphate[no description available]medium10thymidine 5'-monophosphatefundamental metabolite
dipalmitoylphosphatidic acid[no description available]medium10phosphatidic acid
1,2-dipalmitoylphosphatidylglycerol[no description available]medium10phosphatidylglycerol
oltipraz[no description available]medium101,2-dithiole;
pyrazines		angiogenesis modulating agent;
antimutagen;
antineoplastic agent;
antioxidant;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
neurotoxin;
protective agent;
schistosomicide drug
1,2-dithiol-3-thione[no description available]medium101,2-dithiole
thiophenes[no description available]medium10mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound		non-polar solvent
pyrazines[no description available]medium20diazine;
pyrazines		Daphnia magna metabolite
2,2-dimethyl-5-hydroxy-1-pyrrolidinyloxy[no description available]medium10
phytosterols[no description available]medium21
bisphenol a[no description available]medium10bisphenolendocrine disruptor;
environmental contaminant;
xenobiotic;
xenoestrogen
diethylstilbestrol[no description available]medium10olefinic compound;
polyphenol		antifungal agent;
antineoplastic agent;
autophagy inducer;
calcium channel blocker;
carcinogenic agent;
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
endocrine disruptor;
xenoestrogen
ethylmaleimide[no description available]medium20maleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor
carnitine[no description available]medium60amino-acid betainehuman metabolite;
mouse metabolite
s-adenosylmethionine[no description available]medium10sulfonium betainehuman metabolite
porphobilinogen[no description available]medium10aralkylamino compound;
dicarboxylic acid;
pyrroles		Escherichia coli metabolite;
metabolite;
mouse metabolite
corticosterone[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
ro 31-8220[no description available]medium60imidothiocarbamic ester;
indoles;
maleimides		EC 2.7.11.13 (protein kinase C) inhibitor
u 73122[no description available]medium60aromatic ether;
aza-steroid;
maleimides		EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor
u 73343[no description available]medium20
1,2-oleoylphosphatidylcholine[no description available]medium20phosphatidylcholine(1+)
tetradecanoylphorbol acetate[no description available]medium650acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator
probucol[no description available]medium10dithioketal;
polyphenol		anti-inflammatory drug;
anticholesteremic drug;
antilipemic drug;
antioxidant;
cardiovascular drug
ethanolamine[no description available]medium40ethanolamines;
primary alcohol;
primary amine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
taurine[no description available]medium10amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite
trehalose[no description available]medium10trehaloseEscherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
arginine vasopressin[no description available]medium50vasopressincardiovascular drug;
hematologic agent;
mitogen
glycidol[no description available]medium10epoxide;
primary alcohol
valine[no description available]medium10L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
n-(2,3-dihydroxypropyl)valine[no description available]medium10
carbocysteine[no description available]medium10L-cysteine thioether;
non-proteinogenic L-alpha-amino acid		mucolytic
n-formylmethionine leucyl-phenylalanine[no description available]medium160tripeptide
chelerythrine[no description available]medium30benzophenanthridine alkaloid;
organic cation		antibacterial agent;
antineoplastic agent;
EC 2.7.11.13 (protein kinase C) inhibitor
stearic acid[no description available]medium10long-chain fatty acid;
saturated fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
human metabolite;
plant metabolite
linoleic acid[no description available]medium10octadecadienoic acid;
omega-6 fatty acid		algal metabolite;
Daphnia galeata metabolite;
plant metabolite
acetone[no description available]medium10ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
1,3-dioctadecanoylglycerol[no description available]medium10
ha 1004[no description available]medium10isoquinolines
bucladesine[no description available]medium203',5'-cyclic purine nucleotide
1-(5-isoquinolinesulfonyl)-2-methylpiperazine[no description available]medium70isoquinolines;
N-sulfonylpiperazine		EC 2.7.11.13 (protein kinase C) inhibitor
uridine diphosphate galactose[no description available]medium20UDP-D-galactosemouse metabolite
1,6-bismaleimidohexane[no description available]medium10
digalactosyldiacylglycerol[no description available]medium10
urea[no description available]medium10isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
sulfoquinovosyl diglyceride[no description available]medium10
cytidine diphosphate choline[no description available]medium10nucleotide-(amino alcohol)s;
phosphocholines		human metabolite;
mouse metabolite;
neuroprotective agent;
psychotropic drug;
Saccharomyces cerevisiae metabolite
3-methylcholanthrene[no description available]medium10ortho- and peri-fused polycyclic arenearyl hydrocarbon receptor agonist;
carcinogenic agent
coenzyme a[no description available]medium20adenosine 3',5'-bisphosphatecoenzyme;
Escherichia coli metabolite;
mouse metabolite
transforming growth factor alpha[no description available]medium10
ryanodine[no description available]medium10
aristolochic acid i[no description available]medium10aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin
isoproterenol[no description available]medium40catechols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent
caffeine[no description available]medium10purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
8-bromo cyclic adenosine monophosphate[no description available]medium203',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
organobromine compound		antidepressant;
protein kinase agonist
d 609[no description available]medium50
safingol[no description available]medium10amino alcohol
n-oleoylethanolamine[no description available]medium10endocannabinoid;
N-(long-chain-acyl)ethanolamine;
N-acylethanolamine 18:1		EC 3.5.1.23 (ceramidase) inhibitor;
geroprotector;
PPARalpha agonist
phosphorylcholine[no description available]medium70phosphocholinesallergen;
epitope;
hapten;
human metabolite;
mouse metabolite
4-aminobenzoic acid[no description available]medium10aminobenzoic acid;
aromatic amino-acid zwitterion		allergen;
Escherichia coli metabolite;
plant metabolite
4-aminobenzoic acid[no description available]medium10aminobenzoate;
aromatic amino-acid anion		Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
sphingosine kinase[no description available]medium10
cytidine triphosphate[no description available]medium10cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite
1,2-dimethylhydrazine[no description available]medium30hydrazinesalkylating agent;
carcinogenic agent
dinoprostone[no description available]medium60prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic
thromboxane b2[no description available]medium20thromboxanes Bhuman metabolite;
mouse metabolite
thymidine[no description available]medium40pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
dinoprost[no description available]medium80monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite
wortmannin[no description available]medium10acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound		anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent
angiotensin ii[no description available]medium130amino acid zwitterion;
angiotensin II		human metabolite
phosphatidylinositol 4-phosphate[no description available]medium70
pituitrin[no description available]medium120
ergosterol[no description available]medium103beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		fungal metabolite;
Saccharomyces cerevisiae metabolite
dehydroergosterol[no description available]medium103beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		biomarker;
metabolite
pd 98059[no description available]medium10aromatic amine;
monomethoxyflavone		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector
lignans[no description available]medium10
honokiol[no description available]medium10biphenyls
kn 93[no description available]medium10monochlorobenzenes;
monomethoxybenzene;
primary alcohol;
sulfonamide;
tertiary amino compound		EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor;
geroprotector
phorbol 12,13-dibutyrate[no description available]medium130butyrate ester;
phorbol ester;
tertiary alpha-hydroxy ketone
1,2-dihexanoylglycerol[no description available]medium101,2-diglyceride
1-stearoyl-2-linoleoyl-sn-glycerol[no description available]medium201,2-diacyl-sn-glycerol;
diacylglycerol 36:2		mouse metabolite
cysteine[no description available]medium10cysteiniumfundamental metabolite
sincalide[no description available]medium20oligopeptide
proglumide[no description available]medium10benzamides;
dicarboxylic acid monoamide;
glutamine derivative;
racemate		anti-ulcer drug;
cholecystokinin antagonist;
cholinergic antagonist;
delta-opioid receptor agonist;
drug metabolite;
gastrointestinal drug;
opioid analgesic;
xenobiotic metabolite
lorglumide[no description available]medium10benzamides;
dicarboxylic acid monoamide;
dichlorobenzene;
glutamic acid derivative
cr 2945[no description available]medium10
barium[no description available]medium10alkaline earth metal atom;
elemental barium
methacholine chloride[no description available]medium10quaternary ammonium salt
fenofibrate[no description available]medium20aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
pyrroles[no description available]medium20pyrrole;
secondary amine
rottlerin[no description available]medium10aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone		anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite
phosphothreonine[no description available]medium10L-threonine derivative;
non-proteinogenic L-alpha-amino acid;
O-phosphoamino acid		Escherichia coli metabolite
ro 32-0432[no description available]medium10
morphine[no description available]medium10morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic
phenylmethylsulfonyl fluoride[no description available]medium10acyl fluorideserine proteinase inhibitor
4-nitroquinoline-1-oxide[no description available]medium10C-nitro compound;
quinoline N-oxide		carcinogenic agent
phosphotyrosine[no description available]medium20L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid;
O(4)-phosphotyrosine		Escherichia coli metabolite;
immunogen
trypan blue[no description available]medium10
cytochrome c-t[no description available]medium10
glycine[no description available]medium10alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
inositol 1-phosphate[no description available]medium30
inositol[no description available]medium130cyclitol;
hexol
ginsenosides[no description available]medium20
substance p[no description available]medium30peptideneurokinin-1 receptor agonist;
neurotransmitter;
vasodilator agent
phenylephrine[no description available]medium60phenols;
phenylethanolamines;
secondary amino compound		alpha-adrenergic agonist;
cardiotonic drug;
mydriatic agent;
nasal decongestant;
protective agent;
sympathomimetic agent;
vasoconstrictor agent
aspirin[no description available]medium10benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent
calcimycin[no description available]medium170benzoxazole
palmitoyl coenzyme a[no description available]medium1011,12-saturated fatty acyl-CoA;
3-substituted propionyl-CoA;
long-chain fatty acyl-CoA;
palmitoyl bioconjugate		Escherichia coli metabolite;
mouse metabolite
lysophosphatidylethanolamine[no description available]medium10
lysophosphatidylcholines[no description available]medium101-O-acyl-sn-glycero-3-phosphocholine
sodium taurodeoxycholate[no description available]medium10bile acid taurine conjugatehuman metabolite
boc-tyr(s03)-nle-gly-trp-nle-asp-2-phenylethyl ester[no description available]medium10
ceruletide[no description available]medium10oligopeptidediagnostic agent;
gastrointestinal drug
ag-213[no description available]medium10
triiodothyronine[no description available]medium102-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine		human metabolite;
mouse metabolite;
thyroid hormone
cycloheximide[no description available]medium40antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor
diethylnitrosamine[no description available]medium10nitrosaminecarcinogenic agent;
hepatotoxic agent;
mutagen
dimethyl sulfoxide[no description available]medium10sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
st 638[no description available]medium10
framycetin[no description available]medium40aminoglycosideallergen;
antibacterial drug;
Escherichia coli metabolite
p-methoxy-n-methylphenethylamine[no description available]medium20aromatic ether;
secondary amino compound		metabolite
azomethane[no description available]medium10
staurosporine[no description available]medium180ammonium ion derivative
glucose, (beta-d)-isomer[no description available]medium10D-glucopyranoseepitope;
mouse metabolite
cytochalasin b[no description available]medium30cytochalasin;
lactam;
lactone;
organic heterotricyclic compound		actin polymerisation inhibitor;
metabolite;
mycotoxin;
platelet aggregation inhibitor
herbimycin[no description available]medium201,4-benzoquinones;
lactam;
macrocycle		antimicrobial agent;
apoptosis inducer;
herbicide;
Hsp90 inhibitor;
tyrosine kinase inhibitor
fluorides[no description available]medium20halide anion;
monoatomic fluorine
phencyclidine[no description available]medium10benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
concanavalin a[no description available]medium20
bradykinin[no description available]medium70oligopeptidehuman blood serum metabolite;
vasodilator agent
sq-23377[no description available]medium60cyclic ether;
enol;
polyunsaturated fatty acid;
very long-chain fatty acid		calcium ionophore;
metabolite
acetylcarnitine[no description available]medium10O-acylcarnitinehuman metabolite
sorbitol[no description available]medium10glucitolcathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent
phosphatidylethanol[no description available]medium80
halothane[no description available]medium10haloalkane;
organobromine compound;
organochlorine compound;
organofluorine compound		inhalation anaesthetic
propofol[no description available]medium10phenolsanticonvulsant;
antiemetic;
intravenous anaesthetic;
radical scavenger;
sedative
debromoaplysiatoxin[no description available]medium10aplysiatoxins;
cyclic hemiketal;
ether;
organic heterotricyclic compound;
phenols;
secondary alcohol;
spiroketal		algal metabolite;
carcinogenic agent;
cyanotoxin;
marine metabolite;
protein kinase C agonist
propranolol[no description available]medium90naphthalenes;
propanolamine;
secondary amine		anti-arrhythmia drug;
antihypertensive agent;
anxiolytic drug;
beta-adrenergic antagonist;
environmental contaminant;
human blood serum metabolite;
vasodilator agent;
xenobiotic
arginyl-glycyl-aspartic acid[no description available]medium10oligopeptide
myristic acid[no description available]medium50long-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite
cyclic gmp[no description available]medium403',5'-cyclic purine nucleotide;
guanyl ribonucleotide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
ouabain[no description available]medium2011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
phosphorus radioisotopes[no description available]medium20
indomethacin[no description available]medium30aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
inositol 1,4-bis(phosphate)[no description available]medium20
arecoline[no description available]medium10enoate ester;
methyl ester;
pyridine alkaloid;
tetrahydropyridine		metabolite;
muscarinic agonist
1-(carboxymethylthio)tetradecane[no description available]medium10straight-chain fatty acid
1,10-bis(carboxymethylthiodecane)[no description available]medium10
activins[no description available]medium10
potassium chloride[no description available]medium20inorganic chloride;
inorganic potassium salt;
potassium salt		fertilizer
fura-2[no description available]medium10
aflatoxin b1[no description available]medium10aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human metabolite
dieldrin[no description available]medium10epoxide;
organochlorine compound;
organochlorine insecticide		carcinogenic agent;
xenobiotic
inositol 4,5-bisphosphate[no description available]medium10myo-inositol bisphosphate
chlorpromazine[no description available]medium30organochlorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug
technetium tc 99m pentetate[no description available]medium10
omega-(4-iodophenyl)pentadecanoic acid[no description available]medium10
s6c sarafotoxin[no description available]medium20
pyrrolidonecarboxylic acid[no description available]medium105-oxoproline;
L-proline derivative;
non-proteinogenic L-alpha-amino acid		algal metabolite
12-hydroxy-5,8,10,14-eicosatetraenoic acid[no description available]medium10
1-hexadecyl-2-acetyl-glycero-3-phosphocholine[no description available]medium902-acetyl-1-alkyl-sn-glycero-3-phosphocholineantihypertensive agent;
beta-adrenergic antagonist;
bronchoconstrictor agent;
hematologic agent;
vasodilator agent
cromakalim[no description available]medium10
aldosterone[no description available]medium5011beta-hydroxy steroid;
18-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
mineralocorticoid;
primary alpha-hydroxy ketone;
steroid aldehyde		human metabolite;
mouse metabolite
guanosine 5'-o-(2-thiodiphosphate)[no description available]medium10nucleoside diphosphate analogue
oxotremorine m[no description available]medium10quaternary ammonium ionmuscarinic agonist
oxotremorine[no description available]medium10N-alkylpyrrolidine
phosphatidylbutanol[no description available]medium40
n-methylaspartate[no description available]medium10amino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound		neurotransmitter agent
dizocilpine maleate[no description available]medium10maleate salt;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
homocysteine[no description available]medium10amino acid zwitterion;
homocysteine;
serine family amino acid		fundamental metabolite;
mouse metabolite
selfotel[no description available]medium10non-proteinogenic alpha-amino acid
homocysteic acid[no description available]medium10homocysteic acidNMDA receptor agonist
2-methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo(1,2-alpha)pyrazin-3-one[no description available]medium10
vasoactive intestinal peptide[no description available]medium20
n-caproylsphingosine[no description available]medium20N-acylsphingosine
n-acetylsphingosine[no description available]medium20N-acylsphingosine
15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid[no description available]medium10
fibrinogen[no description available]medium10iditolfungal metabolite
endothelin-1[no description available]medium20
verapamil[no description available]medium30aromatic ether;
nitrile;
polyether;
tertiary amino compound
bq 123[no description available]medium10cyclic peptide
luminol[no description available]medium10
diphenyleneiodonium[no description available]medium10organic cation
beta-escin[no description available]medium10
transforming growth factor beta[no description available]medium10
diarachidonyl diglyceride[no description available]medium40
prazosin[no description available]medium30aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
desipramine[no description available]medium20dibenzoazepine;
secondary amino compound		adrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
cholinergic antagonist;
drug allergen;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
serotonin uptake inhibitor
quinazolines[no description available]medium20azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinazolines
ovalbumin[no description available]medium10
magnesium sulfate[no description available]medium10magnesium salt;
metal sulfate;
organic magnesium salt		anaesthetic;
analgesic;
anti-arrhythmia drug;
anticonvulsant;
calcium channel blocker;
cardiovascular drug;
fertilizer;
tocolytic agent
midostaurin[no description available]medium10benzamides;
gamma-lactam;
indolocarbazole;
organic heterooctacyclic compound		antineoplastic agent;
EC 2.7.11.13 (protein kinase C) inhibitor
oxytocin[no description available]medium10heterodetic cyclic peptide;
peptide hormone		oxytocic;
vasodilator agent
bay-k-8644[no description available]medium20(trifluoromethyl)benzenes;
C-nitro compound;
dihydropyridine;
methyl ester
deoxycholic acid[no description available]medium10bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human blood serum metabolite
etomoxir[no description available]medium10aromatic ether
sapintoxin d[no description available]medium10phorbol ester;
tertiary alpha-hydroxy ketone		fluorescent probe;
metabolite
opc 12759[no description available]medium10secondary carboxamide
alanine[no description available]medium10alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite
leukotriene d4[no description available]medium10dipeptide;
leukotriene;
organic sulfide		bronchoconstrictor agent;
human metabolite;
mouse metabolite
carbostyril[no description available]medium10monohydroxyquinoline;
quinolone		bacterial xenobiotic metabolite
orotic acid[no description available]medium20pyrimidinemonocarboxylic acidEscherichia coli metabolite;
metabolite;
mouse metabolite
betadex[no description available]medium10cyclodextrin
nitrendipine[no description available]medium10C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
ethyl ester;
methyl ester		antihypertensive agent;
calcium channel blocker;
geroprotector;
vasodilator agent
go 6976[no description available]medium10indolocarbazole;
organic heterohexacyclic compound		EC 2.7.11.13 (protein kinase C) inhibitor
pentetic acid[no description available]medium10pentacarboxylic acidcopper chelator
ascorbic acid[no description available]medium10ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent
monocrotaline[no description available]medium10pyrrolizidine alkaloid
daunorubicin[no description available]medium10aminoglycoside antibiotic;
anthracycline;
p-quinones;
tetracenequinones		antineoplastic agent;
bacterial metabolite
inositol 1,3,4-trisphosphate[no description available]medium10inositol phosphate oxoanionhuman metabolite
quinacrine[no description available]medium20acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound		antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
ridogrel[no description available]medium10(trifluoromethyl)benzenes
desoxycorticosterone[no description available]medium1020-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
mineralocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
lithium chloride[no description available]medium20inorganic chloride;
lithium salt		antimanic drug;
geroprotector
egtazic acid[no description available]medium70diether;
tertiary amino compound;
tetracarboxylic acid		chelator
chlorine[no description available]medium20halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
phenylglyoxal[no description available]medium10phenylacetaldehydes
manganese[no description available]medium20elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
thromboxanes[no description available]medium10
fructose-1,6-diphosphate[no description available]medium10
lipid a[no description available]medium10dodecanoate ester;
lipid A;
tetradecanoate ester		Escherichia coli metabolite
nigericin[no description available]medium10polycyclic etherantibacterial agent;
antimicrobial agent;
bacterial metabolite;
potassium ionophore
amiloride[no description available]medium10aromatic amine;
guanidines;
organochlorine compound;
pyrazines		diuretic;
sodium channel blocker
ethylisopropylamiloride[no description available]medium10aromatic amine;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines;
tertiary amino compound		anti-arrhythmia drug;
neuroprotective agent;
sodium channel blocker
lanthanum[no description available]medium10f-block element atom;
lanthanoid atom;
scandium group element atom
w 7[no description available]medium10
lanthanum chloride[no description available]medium10
sulfolipid i[no description available]medium10polyacyl alpha,alpha-trehalose derivative;
sulfoglycolipid
phenidone[no description available]medium10
masoprocol[no description available]medium10nordihydroguaiaretic acidantineoplastic agent;
hypoglycemic agent;
lipoxygenase inhibitor;
metabolite
arginylphenylalaninamide[no description available]medium10
dimethylhydrazines[no description available]medium20
2,6-dichloro-4-nitrophenol[no description available]medium10
hymecromone[no description available]medium10hydroxycoumarinantineoplastic agent;
hyaluronic acid synthesis inhibitor
nitrophenols[no description available]medium10
1-monooleoyl-rac-glycerol[no description available]medium201-acylglycerol 18:1;
monooleoylglycerol		plant metabolite
hirudin[no description available]medium10
hydrogen[no description available]medium10elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
atropine[no description available]medium20
calpain[no description available]medium20
nickel[no description available]medium10metal allergen;
nickel group element atom		epitope;
micronutrient
nifedipine[no description available]medium10C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent
inositol cyclic phosphate[no description available]medium10myo-inositol cyclic phosphateepitope
deoxyglucose[no description available]medium10
dimyristoylphosphatidylcholine[no description available]medium101,2-diacyl-sn-glycero-3-phosphocholine;
phosphatidylcholine 28:0;
tetradecanoate ester		antigen;
mouse metabolite
heparitin sulfate[no description available]medium10
arsenic[no description available]medium10metalloid atom;
pnictogen		micronutrient
oxophenylarsine[no description available]medium10arsine oxidesantineoplastic agent;
apoptosis inducer;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor
5'-methylthioadenosine[no description available]medium10thioadenosinealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
adenosine[no description available]medium10adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
alpha-chymotrypsin[no description available]medium10
staurosporine aglycone[no description available]medium10
12-o-tetradeca-2,4,6,8-tetranoylphorbol-13-acetate[no description available]medium10
gallic acid[no description available]medium10trihydroxybenzoic acidantineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite
8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate[no description available]medium10trihydroxybenzoic acid
calmidazolium[no description available]medium10imidazolium ionapoptosis inducer;
calmodulin antagonist
lucifer yellow[no description available]medium10organic lithium saltfluorochrome
prostaglandin f1[no description available]medium10prostaglandins Falphahuman metabolite
substance p, prolyl(2)-tryptophan(7,9)-[no description available]medium10
1-methyl-3-isobutylxanthine[no description available]medium103-isobutyl-1-methylxanthine
c.i. 42510[no description available]medium10
l 451167[no description available]medium10
bromochloroacetic acid[no description available]medium102-bromocarboxylic acid;
monocarboxylic acid;
organochlorine compound
aluminum fluoride[no description available]medium10aluminium coordination entity
inositol 3,4-bisphosphate[no description available]medium10myo-inositol bisphosphatehuman metabolite;
mouse metabolite
pentagastrin[no description available]medium10organic molecular entity
cholecystokinin[no description available]medium10
1,2-distearin[no description available]medium10
1,2-dipalmitoylphosphatidylcholine[no description available]medium10
edetic acid[no description available]medium10ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
tetrodotoxin[no description available]medium10azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid		animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker
papaverine[no description available]medium10benzylisoquinoline alkaloid;
dimethoxybenzene;
isoquinolines		antispasmodic drug;
vasodilator agent
glucagon[no description available]medium20peptide hormone
colforsin[no description available]medium20acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol		adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist
quin2[no description available]medium10
lypressin[no description available]medium10cyclic peptide
leukotriene b4[no description available]medium10dihydroxy monocarboxylic acid;
hydroxy polyunsaturated fatty acid;
leukotriene;
long-chain fatty acid		human metabolite;
mouse metabolite;
plant metabolite;
vasoconstrictor agent
saralasin[no description available]medium10oligopeptide
3-o-methylglucose[no description available]medium20D-aldohexose derivative
glyceraldehyde[no description available]medium10aldotriosefundamental metabolite
aplysiatoxin[no description available]medium10aplysiatoxins;
bromophenol;
cyclic hemiketal;
ether;
organic heterotricyclic compound;
secondary alcohol;
spiroketal		algal metabolite;
carcinogenic agent;
cyanotoxin;
marine metabolite;
protein kinase C agonist
teleocidin b-4[no description available]medium10
melphalan[no description available]medium10L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
deamino arginine vasopressin[no description available]medium10heterodetic cyclic peptidediagnostic agent;
renal agent;
vasopressin receptor agonist
phosphoserine[no description available]medium10non-proteinogenic alpha-amino acid;
O-phosphoamino acid;
serine derivative		human metabolite
pregnenolone[no description available]medium1020-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
C21-steroid		human metabolite;
mouse metabolite
methionine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
phenobarbital[no description available]medium10barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
dihydroxyacetone phosphate[no description available]medium10glycerone phosphates;
primary alpha-hydroxy ketone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
4-bromophenacyl bromide[no description available]medium10
1,2-didecanoylglycerol[no description available]low001,2-diglyceride;
decanoate ester
dimyristoyl diglyceride[no description available]low001,2-diglyceride;
tetradecanoate ester
tetracycline[no description available]medium1110
tetracycline[no description available]medium11115
minocycline[no description available]medium140
phenytoin[no description available]medium10imidazolidine-2,4-dioneanticonvulsant;
drug allergen;
sodium channel blocker;
teratogenic agent
acetaminophen[no description available]medium20acetamides;
phenols		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
cyclooxygenase 3 inhibitor;
environmental contaminant;
ferroptosis inducer;
geroprotector;
hepatotoxic agent;
human blood serum metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
alosetron[no description available]medium10imidazoles;
pyridoindole		antiemetic;
gastrointestinal drug;
serotonergic antagonist
theophylline[no description available]medium20dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent
amiodarone[no description available]medium101-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound		cardiovascular drug
anastrozole[no description available]medium10nitrile;
triazoles		antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor
bumetanide[no description available]medium10amino acid;
benzoic acids;
sulfonamide		diuretic;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
busulfan[no description available]medium10methanesulfonate esteralkylating agent;
antineoplastic agent;
carcinogenic agent;
insect sterilant;
teratogenic agent
candesartan[no description available]medium10benzimidazolecarboxylic acid;
biphenylyltetrazole		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
carbamazepine[no description available]medium10dibenzoazepine;
ureas		analgesic;
anticonvulsant;
antimanic drug;
drug allergen;
EC 3.5.1.98 (histone deacetylase) inhibitor;
environmental contaminant;
glutamate transporter activator;
mitogen;
non-narcotic analgesic;
sodium channel blocker;
xenobiotic
chlorambucil[no description available]medium10aromatic amine;
monocarboxylic acid;
nitrogen mustard;
organochlorine compound;
tertiary amino compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
cimetidine[no description available]medium20aliphatic sulfide;
guanidines;
imidazoles;
nitrile		adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
clofibrate[no description available]medium10aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist
clonazepam[no description available]medium101,4-benzodiazepinone;
monochlorobenzenes		anticonvulsant;
anxiolytic drug;
GABA modulator
clonidine[no description available]medium10clonidine;
imidazoline
dapsone[no description available]medium10substituted aniline;
sulfone		anti-inflammatory drug;
antiinfective agent;
antimalarial;
leprostatic drug
diazepam[no description available]medium101,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic
diflunisal[no description available]medium10monohydroxybenzoic acid;
organofluorine compound		non-narcotic analgesic;
non-steroidal anti-inflammatory drug
diphenhydramine[no description available]medium10ether;
tertiary amino compound		anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative
valproic acid[no description available]medium10branched-chain fatty acid;
branched-chain saturated fatty acid		anticonvulsant;
antimanic drug;
EC 3.5.1.98 (histone deacetylase) inhibitor;
GABA agent;
neuroprotective agent;
psychotropic drug;
teratogenic agent
domperidone[no description available]medium10benzimidazoles;
heteroarylpiperidine		antiemetic;
dopaminergic antagonist
doxazosin[no description available]medium10aromatic amine;
benzodioxine;
monocarboxylic acid amide;
N-acylpiperazine;
N-arylpiperazine;
quinazolines		alpha-adrenergic antagonist;
antihyperplasia drug;
antihypertensive agent;
antineoplastic agent;
vasodilator agent
brl 42810[no description available]medium102-aminopurines;
acetate ester		antiviral drug;
prodrug
flucytosine[no description available]medium20aminopyrimidine;
nucleoside analogue;
organofluorine compound;
pyrimidine antifungal drug;
pyrimidone		prodrug
fluphenazine[no description available]medium10N-alkylpiperazine;
organofluorine compound;
phenothiazines		anticoronaviral agent;
dopaminergic antagonist;
phenothiazine antipsychotic drug
gabapentin[no description available]medium10gamma-amino acidanticonvulsant;
calcium channel blocker;
environmental contaminant;
xenobiotic
glimepiride[no description available]medium10sulfonamide
glipizide[no description available]medium10aromatic amide;
monocarboxylic acid amide;
N-sulfonylurea;
pyrazines		EC 2.7.1.33 (pantothenate kinase) inhibitor;
hypoglycemic agent;
insulin secretagogue
glyburide[no description available]medium10monochlorobenzenes;
N-sulfonylurea		anti-arrhythmia drug;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor;
hypoglycemic agent
granisetron[no description available]medium10aromatic amide;
indazoles
haloperidol[no description available]medium20aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
hydrochlorothiazide[no description available]medium10benzothiadiazine;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
imipramine[no description available]medium10dibenzoazepineadrenergic uptake inhibitor;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
avapro[no description available]medium10azaspiro compound;
biphenylyltetrazole		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
itraconazole[no description available]medium10piperazines
lansoprazole[no description available]medium10benzimidazoles;
pyridines;
sulfoxide		anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
letrozole[no description available]medium10nitrile;
triazoles		antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor
losartan[no description available]medium10biphenylyltetrazole;
imidazoles		angiotensin receptor antagonist;
anti-arrhythmia drug;
antihypertensive agent;
endothelin receptor antagonist
metoclopramide[no description available]medium10benzamides;
monochlorobenzenes;
substituted aniline;
tertiary amino compound		antiemetic;
dopaminergic antagonist;
environmental contaminant;
gastrointestinal drug;
xenobiotic
midazolam[no description available]medium10imidazobenzodiazepine;
monofluorobenzenes;
organochlorine compound		anticonvulsant;
antineoplastic agent;
anxiolytic drug;
apoptosis inducer;
central nervous system depressant;
GABAA receptor agonist;
general anaesthetic;
muscle relaxant;
sedative
milrinone[no description available]medium10bipyridines;
nitrile;
pyridone		cardiotonic drug;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
naratriptan[no description available]medium10heteroarylpiperidine;
sulfonamide;
tryptamines		serotonergic agonist;
vasoconstrictor agent
nevirapine[no description available]medium10cyclopropanes;
dipyridodiazepine		antiviral drug;
HIV-1 reverse transcriptase inhibitor
nimodipine[no description available]medium102-methoxyethyl ester;
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
isopropyl ester		antihypertensive agent;
calcium channel blocker;
cardiovascular drug;
vasodilator agent
nitrazepam[no description available]medium101,4-benzodiazepinone;
C-nitro compound		anticonvulsant;
antispasmodic drug;
drug metabolite;
GABA modulator;
sedative
nizatidine[no description available]medium101,3-thiazoles;
C-nitro compound;
carboxamidine;
organic sulfide;
tertiary amino compound		anti-ulcer drug;
cholinergic drug;
H2-receptor antagonist
pantoprazole[no description available]medium10aromatic ether;
benzimidazoles;
organofluorine compound;
pyridines;
sulfoxide		anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
environmental contaminant;
xenobiotic
phenobarbital[no description available]medium20barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
prazosin[no description available]medium10aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
primidone[no description available]medium10pyrimidoneanticonvulsant;
environmental contaminant;
xenobiotic
procainamide[no description available]medium20benzamidesanti-arrhythmia drug;
platelet aggregation inhibitor;
sodium channel blocker
protriptyline[no description available]medium10carbotricyclic compoundantidepressant
raloxifene[no description available]medium101-benzothiophenes;
aromatic ketone;
N-oxyethylpiperidine;
phenols		bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
risperidone[no description available]medium101,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
psychotropic drug;
second generation antipsychotic;
serotonergic antagonist
rizatriptan[no description available]medium10tryptaminesanti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent
rofecoxib[no description available]medium10butenolide;
sulfone		analgesic;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
ropinirole[no description available]medium20indolones;
tertiary amine		antidyskinesia agent;
antiparkinson drug;
central nervous system drug;
dopamine agonist
saccharin[no description available]medium101,2-benzisothiazole;
N-sulfonylcarboxamide		environmental contaminant;
sweetening agent;
xenobiotic
telenzepine[no description available]medium10benzodiazepine
tolbutamide[no description available]medium10N-sulfonylureahuman metabolite;
hypoglycemic agent;
insulin secretagogue;
potassium channel blocker
ultram[no description available]medium10aromatic ether;
tertiary alcohol;
tertiary amino compound
triamterene[no description available]medium10pteridinesdiuretic;
sodium channel blocker
triazolam[no description available]medium10triazolobenzodiazepinesedative
trimethoprim[no description available]medium30aminopyrimidine;
methoxybenzenes		antibacterial drug;
diuretic;
drug allergen;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
environmental contaminant;
xenobiotic
trimethoprim[no description available]medium31aminopyrimidine;
methoxybenzenes		antibacterial drug;
diuretic;
drug allergen;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
environmental contaminant;
xenobiotic
delavirdine[no description available]medium10aminopyridine;
indolecarboxamide;
N-acylpiperazine;
sulfonamide		antiviral drug;
HIV-1 reverse transcriptase inhibitor
zaleplon[no description available]medium10nitrile;
pyrazolopyrimidine		anticonvulsant;
anxiolytic drug;
central nervous system depressant;
sedative
zolpidem[no description available]medium10imidazopyridinecentral nervous system depressant;
GABA agonist;
sedative
spironolactone[no description available]medium103-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester		aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
prednisone[no description available]medium2011-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
immunosuppressive agent;
prodrug
penicillin g[no description available]medium80penicillin allergen;
penicillin		antibacterial drug;
drug allergen;
epitope
chloramphenicol[no description available]medium190C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
physostigmine[no description available]medium10carbamate ester;
indole alkaloid		antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic
ethinyl estradiol[no description available]medium1017-hydroxy steroid;
3-hydroxy steroid;
terminal acetylenic compound		xenoestrogen
cloxacillin[no description available]medium50penicillin allergen;
penicillin;
semisynthetic derivative		antibacterial agent;
antibacterial drug
cloxacillin[no description available]medium51penicillin allergen;
penicillin;
semisynthetic derivative		antibacterial agent;
antibacterial drug
norethindrone[no description available]medium1017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
terminal acetylenic compound;
tertiary alcohol		progestin;
synthetic oral contraceptive
methylprednisolone[no description available]medium106-methylprednisolone;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antiemetic;
environmental contaminant;
neuroprotective agent;
xenobiotic
fluocortolone[no description available]medium1021-hydroxy steroid
erythromycin[no description available]medium160cyclic ketone;
erythromycin
erythromycin[no description available]medium162cyclic ketone;
erythromycin
levonorgestrel[no description available]medium1017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
terminal acetylenic compound		contraceptive drug;
female contraceptive drug;
progestin;
synthetic oral contraceptive
estradiol valerate[no description available]medium10steroid ester
ethambutol[no description available]medium10ethanolamines;
ethylenediamine derivative		antitubercular agent;
environmental contaminant;
xenobiotic
dronabinol[no description available]medium10benzochromene;
diterpenoid;
phytocannabinoid;
polyketide		cannabinoid receptor agonist;
epitope;
hallucinogen;
metabolite;
non-narcotic analgesic
pimozide[no description available]medium10benzimidazoles;
heteroarylpiperidine;
organofluorine compound		antidyskinesia agent;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
stavudine[no description available]medium10dihydrofuran;
nucleoside analogue;
organic molecular entity		antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
floxacillin[no description available]medium10penicillin allergen;
penicillin		antibacterial drug
levomethadone[no description available]medium106-(dimethylamino)-4,4-diphenylheptan-3-oneantitussive;
mu-opioid receptor agonist;
NMDA receptor antagonist;
opioid analgesic
phenylethylmalonamide[no description available]medium10amine
metopimazine[no description available]medium10phenothiazines
cephalexin[no description available]medium30beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug
metergoline[no description available]medium10carbamate ester;
ergoline alkaloid		dopamine agonist;
geroprotector;
serotonergic antagonist
bromocriptine[no description available]medium20indole alkaloidantidyskinesia agent;
antiparkinson drug;
dopamine agonist;
hormone antagonist
cefazolin[no description available]medium10beta-lactam antibiotic allergen;
cephalosporin;
tetrazoles;
thiadiazoles		antibacterial drug
zidovudine[no description available]medium10azide;
pyrimidine 2',3'-dideoxyribonucleoside		antimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor
ribavirin[no description available]medium101-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide		anticoronaviral agent;
antiinfective agent;
antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
diltiazem[no description available]medium105-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetateantihypertensive agent;
calcium channel blocker;
vasodilator agent
dexibuprofen[no description available]medium10ibuprofennon-narcotic analgesic;
non-steroidal anti-inflammatory drug
torsemide[no description available]medium10aminopyridine;
N-sulfonylurea;
secondary amino compound		antihypertensive agent;
loop diuretic
idarubicin[no description available]medium10anthracycline antibiotic;
deoxy hexoside;
monosaccharide derivative
endralazine[no description available]medium10benzamides
cefaclor anhydrous[no description available]medium10cephalosporinantibacterial drug;
drug allergen
pirazolac[no description available]medium10
lovastatin[no description available]medium10delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		anticholesteremic drug;
antineoplastic agent;
Aspergillus metabolite;
prodrug
enoximone[no description available]medium20aromatic ketone
simvastatin[no description available]medium10delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
statin (semi-synthetic)		EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
ferroptosis inducer;
geroprotector;
prodrug
pravastatin[no description available]medium103-hydroxy carboxylic acid;
carbobicyclic compound;
carboxylic ester;
hydroxy monocarboxylic acid;
secondary alcohol;
statin (semi-synthetic)		anticholesteremic drug;
environmental contaminant;
metabolite;
xenobiotic
atomoxetine[no description available]medium10aromatic ether;
secondary amino compound;
toluenes		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
xenobiotic
eproxindine[no description available]medium10
(S)-nomifensine[no description available]medium10nomifensine
(2S)-2-[[oxo-(4-propan-2-ylcyclohexyl)methyl]amino]-3-phenylpropanoic acid[no description available]medium10phenylalanine derivative
tiagabine[no description available]medium10beta-amino acid;
piperidinemonocarboxylic acid;
tertiary amino compound;
thiophenes		anticonvulsant;
GABA reuptake inhibitor
topotecan[no description available]medium10pyranoindolizinoquinolineantineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor
atorvastatin[no description available]medium10aromatic amide;
dihydroxy monocarboxylic acid;
monofluorobenzenes;
pyrroles;
statin (synthetic)		environmental contaminant;
xenobiotic
lamivudine[no description available]medium10monothioacetal;
nucleoside analogue;
oxacycle;
primary alcohol		allergen;
anti-HBV agent;
antiviral drug;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor;
HIV-1 reverse transcriptase inhibitor;
prodrug
ziprasidone[no description available]medium101,2-benzisothiazole;
indolones;
organochlorine compound;
piperazines		antipsychotic agent;
dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
psychotropic drug;
serotonergic antagonist
zolmitriptan[no description available]medium10oxazolidinone;
tryptamines		anti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent
emtricitabine[no description available]medium10monothioacetal;
nucleoside analogue;
organofluorine compound;
pyrimidone		antiviral drug;
HIV-1 reverse transcriptase inhibitor
pipothiazine[no description available]medium10
oseltamivir[no description available]medium10acetamides;
amino acid ester;
cyclohexenecarboxylate ester;
primary amino compound		antiviral drug;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
environmental contaminant;
prodrug;
xenobiotic
repaglinide[no description available]medium10piperidines
dexfenfluramine[no description available]medium10fenfluramineappetite depressant;
serotonergic agonist;
serotonin uptake inhibitor
drospirenone[no description available]medium103-oxo-Delta(4) steroid;
steroid lactone		aldosterone antagonist;
contraceptive drug;
progestin
fenflumizole[no description available]medium10
prednisolone phosphate[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
glucocorticoid;
steroid phosphate;
tertiary alpha-hydroxy ketone		anti-inflammatory agent;
antineoplastic agent;
glucocorticoid receptor agonist;
prodrug
(S)-flurbiprofen[no description available]medium10flurbiprofen
atovaquone[no description available]medium10hydroxy-1,2-naphthoquinone
eletriptan[no description available]medium10indoles;
N-alkylpyrrolidine;
sulfone		non-steroidal anti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent
flunisolide[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic ketal;
fluorinated steroid;
primary alpha-hydroxy ketone		anti-asthmatic drug;
anti-inflammatory drug;
immunosuppressive agent
clarithromycin[no description available]medium10macrolide antibioticantibacterial drug;
environmental contaminant;
protein synthesis inhibitor;
xenobiotic
moexipril[no description available]medium10peptide
lekoptin[no description available]medium102-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile
tarenflurbil[no description available]medium10flurbiprofen
bosentan anhydrous[no description available]medium10primary alcohol;
pyrimidines;
sulfonamide		antihypertensive agent;
endothelin receptor antagonist
ibuprofen, (r)-isomer[no description available]medium10ibuprofen
pramipexole[no description available]medium10benzothiazoles;
diamine		antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
radical scavenger
almotriptan[no description available]medium10indoles;
sulfonamide;
tertiary amine		non-steroidal anti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent
gefitinib[no description available]medium10aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
quinazolines;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
epidermal growth factor receptor antagonist
methotrexate[no description available]medium20dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
escitalopram[no description available]medium101-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrileantidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
levofloxacin[no description available]medium109-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid;
fluoroquinolone antibiotic;
quinolone antibiotic		antibacterial drug;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor
moxifloxacin[no description available]medium10aromatic ether;
cyclopropanes;
fluoroquinolone antibiotic;
pyrrolidinopiperidine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antibacterial drug
disopyramide, (s)-isomer[no description available]medium10
isradipine, (s)-isomer[no description available]medium10
olmesartan[no description available]medium10biphenylyltetrazoleangiotensin receptor antagonist;
antihypertensive agent
ketoprofen[no description available]medium10
quinidine[no description available]medium10cinchona alkaloidalpha-adrenergic antagonist;
anti-arrhythmia drug;
antimalarial;
drug allergen;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
muscarinic antagonist;
P450 inhibitor;
potassium channel blocker;
sodium channel blocker
digitoxin[no description available]medium10cardenolide glycosideEC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor
saquinavir[no description available]medium10L-asparagine derivative;
quinolines		antiviral drug;
HIV protease inhibitor
abacavir[no description available]medium102,6-diaminopurinesantiviral drug;
drug allergen;
HIV-1 reverse transcriptase inhibitor
linezolid[no description available]medium10acetamides;
morpholines;
organofluorine compound;
oxazolidinone		antibacterial drug;
protein synthesis inhibitor
chloramphenicol palmitate[no description available]medium10hexadecanoate ester
tacrolimus[no description available]medium10macrolide lactambacterial metabolite;
immunosuppressive agent
mycophenolic acid[no description available]medium102-benzofurans;
gamma-lactone;
monocarboxylic acid;
phenols		anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
environmental contaminant;
immunosuppressive agent;
mycotoxin;
Penicillium metabolite;
xenobiotic
chloroquine diphosphate[no description available]medium10chloroquine
dextromethadone[no description available]medium106-(dimethylamino)-4,4-diphenylheptan-3-oneNMDA receptor antagonist;
opioid analgesic
propylthiouracil[no description available]medium10pyrimidinethioneantidote to paracetamol poisoning;
antimetabolite;
antioxidant;
antithyroid drug;
carcinogenic agent;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
hormone antagonist
dexketoprofen[no description available]medium10benzophenones;
monocarboxylic acid		cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
ondansetron, (s)-isomer[no description available]medium10
eszopiclone[no description available]medium10zopiclonecentral nervous system depressant;
sedative
methimazole[no description available]medium101,3-dihydroimidazole-2-thionesantithyroid drug
digoxin[no description available]medium10cardenolide glycoside;
steroid saponin		anti-arrhythmia drug;
cardiotonic drug;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
epitope
hmr 3647[no description available]medium10
tocainide, (s)-isomer[no description available]medium10
calcitriol[no description available]medium10D3 vitamins;
hydroxycalciol;
triol		antineoplastic agent;
antipsoriatic;
bone density conservation agent;
calcium channel agonist;
calcium channel modulator;
hormone;
human metabolite;
immunomodulator;
metabolite;
mouse metabolite;
nutraceutical
clavulanic acid[no description available]medium10oxapenamantibacterial drug;
anxiolytic drug;
bacterial metabolite;
EC 3.5.2.6 (beta-lactamase) inhibitor
pulmicort[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic acetal;
glucocorticoid;
primary alpha-hydroxy ketone		anti-inflammatory drug;
bronchodilator agent;
drug allergen
montelukast[no description available]medium10aliphatic sulfide;
monocarboxylic acid;
quinolines		anti-arrhythmia drug;
anti-asthmatic drug;
leukotriene antagonist
codeine[no description available]medium10morphinane alkaloid;
organic heteropentacyclic compound		antitussive;
drug allergen;
environmental contaminant;
opioid analgesic;
opioid receptor agonist;
prodrug;
xenobiotic
hydromorphone[no description available]medium10morphinane alkaloid;
organic heteropentacyclic compound		mu-opioid receptor agonist;
opioid analgesic
naloxone[no description available]medium10morphinane alkaloid;
organic heteropentacyclic compound;
tertiary alcohol		antidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist
proscillaridin[no description available]medium10organic molecular entity
sirolimus[no description available]medium10antibiotic antifungal drug;
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
organic heterotricyclic compound;
secondary alcohol		antibacterial drug;
anticoronaviral agent;
antineoplastic agent;
bacterial metabolite;
geroprotector;
immunosuppressive agent;
mTOR inhibitor
topiramate[no description available]medium10cyclic ketal;
ketohexose derivative;
sulfamate ester		anticonvulsant;
sodium channel blocker
fluticasone[no description available]medium1011beta-hydroxy steroid;
17alpha-hydroxy steroid;
3-oxo-Delta(4) steroid;
corticosteroid;
fluorinated steroid;
thioester		anti-allergic agent;
anti-asthmatic drug
nalbuphine[no description available]medium10organic heteropentacyclic compoundmu-opioid receptor antagonist;
opioid analgesic
(6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid[no description available]medium10dihydroxy monocarboxylic acid;
indoles;
organofluorine compound
naltrexone[no description available]medium10cyclopropanes;
morphinane-like compound;
organic heteropentacyclic compound		antidote to opioid poisoning;
central nervous system depressant;
environmental contaminant;
mu-opioid receptor antagonist;
xenobiotic
enalapril[no description available]medium10dicarboxylic acid monoester;
dipeptide		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
geroprotector;
prodrug
trandolapril[no description available]medium10dicarboxylic acid monoester;
dipeptide;
ethyl ester;
organic heterobicyclic compound;
secondary amino compound;
tertiary carboxamide		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug
(R)-citalopram[no description available]medium101-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
1-methyl-d-lysergic acid butanolamide[no description available]medium10ergot alkaloid;
monocarboxylic acid amide		serotonergic antagonist;
sympatholytic agent;
vasoconstrictor agent
nitrofurantoin[no description available]medium40imidazolidine-2,4-dione;
nitrofuran antibiotic;
organonitrogen heterocyclic antibiotic;
organooxygen heterocyclic antibiotic		antibacterial drug;
antiinfective agent;
hepatotoxic agent
dutasteride[no description available]medium10(trifluoromethyl)benzenes;
aza-steroid;
delta-lactam		antihyperplasia drug;
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
gemifloxacin[no description available]medium101,8-naphthyridine derivative;
fluoroquinolone antibiotic;
monocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antimicrobial agent;
topoisomerase IV inhibitor
norfenfluramine[no description available]medium10amphetamines
milnacipran[no description available]medium10acetamides
chlortetracycline[no description available]medium350
oxytetracycline, anhydrous[no description available]medium700
oxytetracycline, anhydrous[no description available]medium702
piroxicam[no description available]medium10benzothiazine;
monocarboxylic acid amide;
pyridines		analgesic;
antirheumatic drug;
cyclooxygenase 1 inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
(S)-warfarin[no description available]medium104-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one
rifampin[no description available]medium70cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
clozapine[no description available]medium20benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound		adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic
sildenafil[no description available]medium10piperazines;
pyrazolopyrimidine;
sulfonamide		EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent
vardenafil[no description available]medium10imidazotriazine;
N-alkylpiperazine;
N-sulfonylpiperazine		EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
vasodilator agent
aprepitant[no description available]medium10(trifluoromethyl)benzenes;
cyclic acetal;
morpholines;
triazoles		antidepressant;
antiemetic;
neurokinin-1 receptor antagonist;
peripheral nervous system drug;
substance P receptor antagonist
kanamycin a[no description available]medium90kanamycinsbacterial metabolite
framycetin[no description available]medium50aminoglycosideallergen;
antibacterial drug;
Escherichia coli metabolite
streptomycin[no description available]medium70antibiotic antifungal drug;
antibiotic fungicide;
streptomycins		antibacterial drug;
antifungal agrochemical;
antimicrobial agent;
antimicrobial drug;
bacterial metabolite;
protein synthesis inhibitor
streptomycin[no description available]medium71antibiotic antifungal drug;
antibiotic fungicide;
streptomycins		antibacterial drug;
antifungal agrochemical;
antimicrobial agent;
antimicrobial drug;
bacterial metabolite;
protein synthesis inhibitor
bisbenzimidazole trihydrochloride[no description available]medium10
meclocycline[no description available]medium10
metastat[no description available]medium10
demeclocycline[no description available]medium420
demeclocycline[no description available]medium424
tigecycline[no description available]medium10
pk 11195[no description available]medium10aromatic amide;
isoquinolines;
monocarboxylic acid amide;
monochlorobenzenes		antineoplastic agent
jtv519[no description available]medium10
alprazolam[no description available]medium10organochlorine compound;
triazolobenzodiazepine		anticonvulsant;
anxiolytic drug;
GABA agonist;
muscle relaxant;
sedative;
xenobiotic
dan 2163[no description available]medium10aromatic amide;
aromatic amine;
benzamides;
pyrrolidines;
sulfone		environmental contaminant;
second generation antipsychotic;
xenobiotic
amlexanox[no description available]medium10monocarboxylic acid;
pyridochromene		anti-allergic agent;
anti-ulcer drug;
non-steroidal anti-inflammatory drug
astemizole[no description available]medium10benzimidazoles;
piperidines		anti-allergic agent;
anticoronaviral agent;
H1-receptor antagonist
benzbromarone[no description available]medium101-benzofurans;
aromatic ketone		uricosuric drug
bisindolylmaleimide i[no description available]medium10
bufexamac[no description available]medium10aromatic ether;
hydroxamic acid		antipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
cadralazine[no description available]medium10organic molecular entity
carvedilol[no description available]medium10carbazoles;
secondary alcohol;
secondary amino compound		alpha-adrenergic antagonist;
antihypertensive agent;
beta-adrenergic antagonist;
cardiovascular drug;
vasodilator agent
cetirizine[no description available]medium10ether;
monocarboxylic acid;
monochlorobenzenes;
piperazines		anti-allergic agent;
environmental contaminant;
H1-receptor antagonist;
xenobiotic
chlorcyclizine[no description available]medium10diarylmethane
ci 994[no description available]medium10acetamides;
benzamides;
substituted aniline		antineoplastic agent;
EC 3.5.1.98 (histone deacetylase) inhibitor
fenbendazole[no description available]medium10aryl sulfide;
benzimidazoles;
carbamate ester		antinematodal drug
homochlorocyclizine[no description available]medium10diarylmethane
hydroxyzine[no description available]medium10hydroxyether;
monochlorobenzenes;
N-alkylpiperazine		anticoronaviral agent;
antipruritic drug;
anxiolytic drug;
dermatologic drug;
H1-receptor antagonist
ifenprodil[no description available]medium10piperidines
1-(2-naphthalenyl)-3-[(phenylmethyl)-propan-2-ylamino]-1-propanone[no description available]medium10naphthalenes
ketamine[no description available]medium10cyclohexanones;
monochlorobenzenes;
secondary amino compound		analgesic;
environmental contaminant;
intravenous anaesthetic;
neurotoxin;
NMDA receptor antagonist;
xenobiotic
ketoprofen[no description available]medium10benzophenones;
oxo monocarboxylic acid		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
mebendazole[no description available]medium10aromatic ketone;
benzimidazoles;
carbamate ester		antinematodal drug;
microtubule-destabilising agent;
tubulin modulator
mephenesin[no description available]medium10aromatic ether;
glycerol ether
niclosamide[no description available]medium10benzamides;
C-nitro compound;
monochlorobenzenes;
salicylanilides;
secondary carboxamide		anthelminthic drug;
anticoronaviral agent;
antiparasitic agent;
apoptosis inducer;
molluscicide;
piscicide;
STAT3 inhibitor
oxibendazole[no description available]medium10benzimidazoles;
carbamate ester
4-(2'-methoxyphenyl)-1-(2'-(n-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine[no description available]medium10
perphenazine[no description available]medium10N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines		antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug
pimobendan[no description available]medium10benzimidazoles;
pyridazinone		cardiotonic drug;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
vasodilator agent
ag 1879[no description available]medium10aromatic amine;
monochlorobenzenes;
pyrazolopyrimidine		beta-adrenergic antagonist;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector
ro 31-8220[no description available]medium10imidothiocarbamic ester;
indoles;
maleimides		EC 2.7.11.13 (protein kinase C) inhibitor
vorinostat[no description available]medium10dicarboxylic acid diamide;
hydroxamic acid		antineoplastic agent;
apoptosis inducer;
EC 3.5.1.98 (histone deacetylase) inhibitor
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole[no description available]medium10aromatic primary alcohol;
furans;
indazoles		antineoplastic agent;
apoptosis inducer;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent
zotepine[no description available]medium10dibenzothiepine;
tertiary amino compound		alpha-adrenergic drug;
second generation antipsychotic;
serotonergic drug
colchicine[no description available]medium10alkaloid;
colchicine		anti-inflammatory agent;
gout suppressant;
mutagen
benziodarone[no description available]medium10aromatic ketone
cyclizine[no description available]medium10N-alkylpiperazineantiemetic;
central nervous system depressant;
cholinergic antagonist;
H1-receptor antagonist;
local anaesthetic
triclocarban[no description available]medium10dichlorobenzene;
monochlorobenzenes;
phenylureas		antimicrobial agent;
antiseptic drug;
disinfectant;
environmental contaminant;
xenobiotic
4-tert-octylphenol[no description available]medium10alkylbenzene
ethamivan[no description available]medium10methoxybenzenes;
phenols
methysergide[no description available]medium10ergoline alkaloid
emetine[no description available]medium10isoquinoline alkaloid;
pyridoisoquinoline		antiamoebic agent;
anticoronaviral agent;
antiinfective agent;
antimalarial;
antineoplastic agent;
antiprotozoal drug;
antiviral agent;
autophagy inhibitor;
emetic;
expectorant;
plant metabolite;
protein synthesis inhibitor
podophyllotoxin[no description available]medium10furonaphthodioxole;
lignan;
organic heterotetracyclic compound		antimitotic;
antineoplastic agent;
keratolytic drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator
etonitazene[no description available]medium10
clothiapine[no description available]medium10dibenzothiazepine
benperidol[no description available]medium10aromatic ketone
7-hydroxychlorpromazine[no description available]medium10phenothiazines
camptothecin[no description available]medium10delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite
thenalidine[no description available]medium10dialkylarylamine;
tertiary amino compound
dexchlorpheniramine[no description available]medium10chlorphenamine
dv 1006[no description available]medium10
climbazole[no description available]medium10aromatic ether;
hemiaminal ether;
imidazoles;
ketone;
monochlorobenzenes
triadimenol[no description available]medium10aromatic ether;
conazole fungicide;
hemiaminal ether;
monochlorobenzenes;
secondary alcohol;
triazole fungicide		antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
xenobiotic metabolite
amonafide[no description available]medium10isoquinolines
flupirtine[no description available]medium10aminopyridine
chaetochromin[no description available]medium10
aripiprazole[no description available]medium10aromatic ether;
delta-lactam;
dichlorobenzene;
N-alkylpiperazine;
N-arylpiperazine;
quinolone		drug metabolite;
H1-receptor antagonist;
second generation antipsychotic;
serotonergic agonist
aloxistatin[no description available]medium10epoxide;
ethyl ester;
L-leucine derivative;
monocarboxylic acid amide		anticoronaviral agent;
cathepsin B inhibitor
indocate[no description available]medium10
N(4)-acetylsulfathiazole[no description available]medium101,3-thiazoles;
acetamides;
sulfonamide		marine xenobiotic metabolite
2,3-trimethylene-4-quinazolone[no description available]medium10quinazolines
1,3-dimethyluric acid[no description available]medium10oxopurinemetabolite
danofloxacin[no description available]medium10quinolines
nitrefazole[no description available]medium10imidazoles
methotrimeprazine[no description available]medium10phenothiazines;
tertiary amine		anticoronaviral agent;
cholinergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
non-narcotic analgesic;
phenothiazine antipsychotic drug;
serotonergic antagonist
9-methoxyellipticine[no description available]medium10
3-aminophenoxazone[no description available]medium10phenoxazine
3-deazaneplanocin[no description available]medium10
tryptanthrine[no description available]medium10alkaloid antibiotic;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound
2-chlorodiazepam[no description available]medium10
Polycartine B[no description available]medium10phenazines
aminoquinuride dihydrochloride[no description available]medium10
thioproperazine mesylate[no description available]medium10phenothiazines
n(6)-(delta(2)-isopentenyl)adenine[no description available]medium106-isopentenylaminopurinecytokinin
4-methyl-N-(phenylmethyl)benzenesulfonamide[no description available]medium10sulfonamide
zpck[no description available]medium10
sr141716[no description available]medium10amidopiperidine;
carbohydrazide;
dichlorobenzene;
monochlorobenzenes;
pyrazoles		anti-obesity agent;
appetite depressant;
CB1 receptor antagonist
fingolimod[no description available]medium10aminodiol;
primary amino compound		antineoplastic agent;
CB1 receptor antagonist;
immunosuppressive agent;
prodrug;
sphingosine-1-phosphate receptor agonist
tesmilifene[no description available]medium10diarylmethane
sr 27897[no description available]medium10indolyl carboxylic acid
n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine[no description available]medium10leucine derivative
norketamine[no description available]medium10organochlorine compound
indatraline[no description available]medium10indanes
salvinorin a[no description available]medium10organic heterotricyclic compound;
organooxygen compound		metabolite;
oneirogen
4-diethoxyphosphorylmethyl-n-(4-bromo-2-cyanophenyl)benzamide[no description available]medium10
n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide[no description available]medium10phenylindole
l 741626[no description available]medium10piperidines
dx 8951[no description available]medium10pyranoindolizinoquinoline
tipifarnib[no description available]medium10imidazoles;
monochlorobenzenes;
primary amino compound;
quinolone		antineoplastic agent;
apoptosis inducer;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor
cyc 202[no description available]medium102,6-diaminopurinesantiviral drug;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
avasimibe[no description available]medium10monoterpenoid
l 163191[no description available]medium10
dizocilpine[no description available]medium10secondary amino compound;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
s-benzylcysteine[no description available]medium10S-aryl-L-cysteine zwitterion
chelidonine[no description available]medium10alkaloid antibiotic;
alkaloid fundamental parent;
benzophenanthridine alkaloid
lapatinib[no description available]medium10furans;
organochlorine compound;
organofluorine compound;
quinazolines		antineoplastic agent;
tyrosine kinase inhibitor
roxindole[no description available]medium10indolesalpha-adrenergic antagonist;
serotonergic drug
conidendrin[no description available]medium10
Porfiromycine[no description available]medium10mitomycin
nsc 95397[no description available]medium101,4-naphthoquinones
4-methyl-2-quinazolinamine[no description available]medium10
2-glycineamide-5-chlorophenyl-2-pyrryl ketone[no description available]medium10
niguldipine hydrochloride[no description available]medium10
2,5-bis(5-hydroxymethyl-2-thienyl)furan[no description available]medium10thiophenes
ritonavir[no description available]medium101,3-thiazoles;
carbamate ester;
carboxamide;
L-valine derivative;
ureas		antiviral drug;
environmental contaminant;
HIV protease inhibitor;
xenobiotic
bardoxolone methyl[no description available]medium10cyclohexenones
Destruxin B[no description available]medium10cyclodepsipeptide
tosylphenylalanyl chloromethyl ketone[no description available]medium10alpha-chloroketone;
sulfonamide		alkylating agent;
serine proteinase inhibitor
trichostatin a[no description available]medium10antibiotic antifungal agent;
hydroxamic acid;
trichostatin		bacterial metabolite;
EC 3.5.1.98 (histone deacetylase) inhibitor;
geroprotector
sitafloxacin[no description available]medium10fluoroquinolone antibiotic;
quinolines;
quinolone antibiotic
2'-c-methylcytidine[no description available]medium10
jp-1302[no description available]medium10
7-chloro-5,10-dihydrothieno[3,4-b][1,5]benzodiazepin-4-one[no description available]medium10benzodiazepine
tenatoprazole[no description available]medium10imidazopyridine
s 1033[no description available]medium10(trifluoromethyl)benzenes;
imidazoles;
pyridines;
pyrimidines;
secondary amino compound;
secondary carboxamide		anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor
5-[(2-fluoroanilino)methyl]-8-quinolinol[no description available]medium10hydroxyquinoline
benidipine[no description available]medium10
2-(1,3-benzoxazol-2-ylamino)-5-spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclopentane]one[no description available]medium10quinazolines
chlorprothixene[no description available]medium10chlorprothixene
jrf 12[no description available]medium10
5-amino-3-(4-methoxyphenyl)-4-oxo-1-thieno[3,4-d]pyridazinecarboxylic acid ethyl ester[no description available]medium10methoxybenzenes;
substituted aniline
3-hydroxypyridine, sodium salt[no description available]medium10
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1-naphthalenecarboxamide[no description available]medium10naphthalenecarboxamide
5-[(2-bromoanilino)methyl]-8-quinolinol[no description available]medium10hydroxyquinoline
3-amino-n-(4-methoxybenzyl)-4,6-dimethylthieno(2,3-b)pyridine-2-carboxamide[no description available]medium10
N-[(2-methoxyphenyl)methyl]-4-(1-piperidinyl)aniline[no description available]medium10aromatic amine
1-[4-(4-bromophenyl)-2-thiazolyl]-4-piperidinecarboxamide[no description available]medium10piperidinecarboxamide
5-[[2-(trifluoromethyl)anilino]methyl]-8-quinolinol[no description available]medium10hydroxyquinoline
N-[3-[2-[(4-methyl-2-pyridinyl)amino]-4-thiazolyl]phenyl]acetamide[no description available]medium10acetamides;
anilide
5-bromo-N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-2-thiophenecarboxamide[no description available]medium10aromatic amide;
thiophenes
6-amino-1-[2-(3,4-dimethoxyphenyl)ethyl]-2-sulfanylidene-4-pyrimidinone[no description available]medium10dimethoxybenzene
N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-6,8-dimethyl-2-(2-pyridinyl)-4-quinolinecarboxamide[no description available]medium10aromatic amide
N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-5-methyl-3-phenyl-4-isoxazolecarboxamide[no description available]medium10aromatic ether
3-chloro-1-(2,5-dimethoxyphenyl)-4-(1-piperidinyl)pyrrole-2,5-dione[no description available]medium10maleimides
Src Inhibitor-1[no description available]medium10aromatic ether;
polyether;
quinazolines;
secondary amino compound		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
1-[2-(3,4-dimethoxyphenyl)ethyl]-6-propyl-2-sulfanylidene-7,8-dihydro-5H-pyrimido[4,5-d]pyrimidin-4-one[no description available]medium10dimethoxybenzene
2-phenyl-N-[4-(2-thiazolylsulfamoyl)phenyl]-4-quinolinecarboxamide[no description available]medium10quinolines
3-(2,5-dimethyl-1-phenyl-3-pyrrolyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine[no description available]medium10pyrroles
bi-78d3[no description available]medium10aryl sulfide
kartogenin[no description available]medium10
toremifene[no description available]medium10aromatic ether;
organochlorine compound;
tertiary amine		antineoplastic agent;
bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
vx-745[no description available]medium10aryl sulfide;
dichlorobenzene;
difluorobenzene;
pyrimidopyridazine		anti-inflammatory drug;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
dasatinib[no description available]medium101,3-thiazoles;
aminopyrimidine;
monocarboxylic acid amide;
N-(2-hydroxyethyl)piperazine;
N-arylpiperazine;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor
zd 6474[no description available]medium10aromatic ether;
organobromine compound;
organofluorine compound;
piperidines;
quinazolines;
secondary amine		antineoplastic agent;
tyrosine kinase inhibitor
N-[2-(diethylamino)ethyl]-5-[(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide[no description available]medium10indoles
nih-12848[no description available]medium10
2,4-dioxo-3-pentyl-N-[3-(1-piperidinyl)propyl]-1H-quinazoline-7-carboxamide[no description available]medium10quinazolines
[1-(3-methylphenyl)-5-benzimidazolyl]-(1-piperidinyl)methanone[no description available]medium10benzimidazoles
2-[[(6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)thio]methyl]benzonitrile[no description available]medium10imidazopyridine
3-[(3-fluorophenyl)methyl]-8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one[no description available]medium10aromatic ketone
4-[[7-[(4-fluorophenyl)methyl]-1,3-dimethyl-2,6-dioxo-8-purinyl]methyl]-1-piperazinecarboxylic acid ethyl ester[no description available]medium10oxopurine
N,N-dimethylcarbamodithioic acid (1-acetamido-2,2,2-trichloroethyl) ester[no description available]medium10organonitrogen compound;
organosulfur compound
6-bromo-2-(4-methylphenyl)-N-[(1-methyl-4-pyrazolyl)methyl]-4-quinolinecarboxamide[no description available]medium10quinolines
LSM-1924[no description available]medium10organic heterotricyclic compound;
organooxygen compound
ferrostatin-1[no description available]medium10ethyl ester;
primary arylamine;
substituted aniline		antifungal agent;
antioxidant;
ferroptosis inhibitor;
neuroprotective agent;
radiation protective agent;
radical scavenger
6-(2-methyl-1-piperidinyl)-5-nitro-4-pyrimidinamine[no description available]medium10C-nitro compound
rabeprazole(1-)[no description available]medium10organic nitrogen anion
ncgc00099374[no description available]medium10
2-nitro-4-[(6-nitro-4-quinolinyl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide[no description available]medium10benzamides
luteolin[no description available]medium103'-hydroxyflavonoid;
tetrahydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
c-Jun N-terminal kinase inhibitor;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
immunomodulator;
nephroprotective agent;
plant metabolite;
radical scavenger;
vascular endothelial growth factor receptor antagonist
kaempferol[no description available]medium107-hydroxyflavonol;
flavonols;
tetrahydroxyflavone		antibacterial agent;
geroprotector;
human blood serum metabolite;
human urinary metabolite;
human xenobiotic metabolite;
plant metabolite
genistein[no description available]medium107-hydroxyisoflavonesantineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor
mycophenolate mofetil[no description available]medium10carboxylic ester;
ether;
gamma-lactone;
phenols;
tertiary amino compound		anticoronaviral agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
immunosuppressive agent;
prodrug
bruceantin[no description available]medium10triterpenoid
chrysin[no description available]medium107-hydroxyflavonol;
dihydroxyflavone		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
EC 2.7.11.18 (myosin-light-chain kinase) inhibitor;
hepatoprotective agent;
plant metabolite
daidzein[no description available]medium107-hydroxyisoflavonesantineoplastic agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
phytoestrogen;
plant metabolite
neticonazole[no description available]medium10aromatic ether;
benzenes;
conazole antifungal drug;
enamine;
imidazole antifungal drug;
imidazoles;
methyl sulfide		antifungal drug;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoylethanolamine[no description available]medium10endocannabinoid;
N-acylethanolamine 22:6
alpha-zearalenol[no description available]medium10macrolide
su 9516[no description available]medium10
N-(4-bromo-3-methylphenyl)-2,5-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine[no description available]medium10triazolopyrimidines
sb 277011[no description available]medium10
sb 223412[no description available]medium10
sr 59230a[no description available]medium10tetralins
3-[6-[4-(trifluoromethoxy)anilino]-4-pyrimidinyl]benzamide[no description available]medium10pyrimidines
kn 62[no description available]medium10piperazines
MeJA[no description available]medium10Jasmonate derivatives
1h-pyrrole-2,5-dione, 3-(1-methyl-1h-indol-3-yl)-4-(1-methyl-6-nitro-1h-indol-3-yl)-[no description available]medium10
pd 161570[no description available]medium10
palbociclib[no description available]medium10aminopyridine;
aromatic ketone;
cyclopentanes;
piperidines;
pyridopyrimidine;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
jnj-7706621[no description available]medium10sulfonamide
virginiamycin factor s1[no description available]medium10cyclodepsipeptide;
macrolide antibiotic		antibacterial drug;
bacterial metabolite
fenoterol[no description available]medium10hydrobromidebeta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent
xib 4035[no description available]medium10
gw-5074[no description available]medium10
belotecan[no description available]medium10pyranoindolizinoquinoline
norgestimate[no description available]medium10ketoxime;
steroid ester;
terminal acetylenic compound		contraceptive drug;
progestin;
synthetic oral contraceptive
b 43[no description available]medium10aromatic amine;
aromatic ether;
cyclopentanes;
primary amino compound;
pyrrolopyrimidine		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector
4-(2' methoxyphenyl)-1-(2'-(n-(2''-pyridinyl)-4-fluorobenzamido)ethyl)piperazine[no description available]medium10
methiazole[no description available]medium10benzimidazoles;
carbamate ester
sb 218795[no description available]medium10quinolines
bvt.948[no description available]medium10
fk 866[no description available]medium10benzamides;
N-acylpiperidine
a 38503[no description available]medium10
parthenolide[no description available]medium10sesquiterpene lactonedrug allergen;
inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug
krn 633[no description available]medium10
5-amino-4-oxo-3-phenyl-1-thieno[3,4-d]pyridazinecarboxylic acid[no description available]medium10organonitrogen heterocyclic compound;
organosulfur heterocyclic compound
gw 501516[no description available]medium101,3-thiazoles;
aromatic ether;
aryl sulfide;
monocarboxylic acid;
organofluorine compound		carcinogenic agent;
PPARbeta/delta agonist
dolastatin 10[no description available]medium101,3-thiazoles;
tetrapeptide		animal metabolite;
antineoplastic agent;
apoptosis inducer;
marine metabolite;
microtubule-destabilising agent
spc-839[no description available]medium10
valnemulin[no description available]medium10
nu 7026[no description available]medium10organic heterotricyclic compound;
organooxygen compound
osi 930[no description available]medium10aromatic amide
ticagrelor[no description available]medium10aryl sulfide;
hydroxyether;
organofluorine compound;
secondary amino compound;
triazolopyrimidines		P2Y12 receptor antagonist;
platelet aggregation inhibitor
l 692585[no description available]medium10peptide
pi103[no description available]medium10aromatic amine;
morpholines;
organic heterotricyclic compound;
phenols;
tertiary amino compound		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor
nnc 26-9100[no description available]medium10aminopyridine
2-(3-chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine[no description available]medium10
tivozanib[no description available]medium10aromatic ether
hki 272[no description available]medium10nitrile;
quinolines		antineoplastic agent;
tyrosine kinase inhibitor
n-(6-chloro-7-methoxy-9h-beta-carbolin-8-yl)-2-methylnicotinamide[no description available]medium10
tae226[no description available]medium10morpholines
gw0742[no description available]medium10monocarboxylic acid
u 18666a[no description available]medium10hydrochlorideantiviral agent;
EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor;
Hedgehog signaling pathway inhibitor;
nicotinic antagonist;
sterol biosynthesis inhibitor
sb 525334[no description available]medium10quinoxaline derivative
bx795[no description available]medium10ureas
azd 6244[no description available]medium10benzimidazoles;
bromobenzenes;
hydroxamic acid ester;
monochlorobenzenes;
organofluorine compound;
secondary amino compound		anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
1-(2-(1-adamantyl)ethyl)-1-pentyl-3-(3-(4-pyridyl)propyl)urea[no description available]medium10
bay 61-3606[no description available]medium10pyrimidines
sd-208[no description available]medium10
crenolanib[no description available]medium10aminopiperidine;
aromatic ether;
benzimidazoles;
oxetanes;
quinolines;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
cj 033466[no description available]medium10
cc 401[no description available]medium10pyrazoles;
ring assembly
PB28[no description available]medium10aromatic ether;
piperazines;
tetralins		anticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
sigma-2 receptor agonist
arterolane[no description available]medium10
cariprazine[no description available]medium10
krp-203[no description available]medium10
regorafenib[no description available]medium10(trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
phenylureas;
pyridinecarboxamide		antineoplastic agent;
hepatotoxic agent;
tyrosine kinase inhibitor
at 7867[no description available]medium10monochlorobenzenes;
piperidines;
pyrazoles		antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
acetic acid 2-[4-methyl-8-(4-morpholinylsulfonyl)-1,3-dioxo-2-pyrrolo[3,4-c]quinolinyl]ethyl ester[no description available]medium10pyrroloquinoline
ptc 124[no description available]medium10oxadiazole;
ring assembly
degrasyn[no description available]medium10
bi 2536[no description available]medium10
azd 1152[no description available]medium10anilide;
monoalkyl phosphate;
monofluorobenzenes;
pyrazoles;
quinazolines;
secondary amino compound;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
Aurora kinase inhibitor;
prodrug
carfilzomib[no description available]medium10epoxide;
morpholines;
tetrapeptide		antineoplastic agent;
proteasome inhibitor
idelalisib[no description available]medium10aromatic amine;
organofluorine compound;
purines;
quinazolines;
secondary amino compound		antineoplastic agent;
apoptosis inducer;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
motesanib[no description available]medium10pyridinecarboxamide
pf-562,271[no description available]medium10indoles
gliocladin c[no description available]medium10
sb 706504[no description available]medium10
ku-0060648[no description available]medium10dibenzothiophenes
bgt226[no description available]medium10aromatic ether;
imidazoquinoline;
N-arylpiperazine;
organofluorine compound;
pyridines		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor
n-desmethyldanofloxacin[no description available]medium10
azd 1152-hqpa[no description available]medium10anilide;
monofluorobenzenes;
primary alcohol;
pyrazoles;
quinazolines;
secondary amino compound;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
Aurora kinase inhibitor
CDN1163[no description available]medium10aromatic ether;
quinolines;
secondary carboxamide		SERCA activator
gsk 269962a[no description available]medium10
pha 848125[no description available]medium10
nvp-bhg712[no description available]medium10benzamides
pf 04217903[no description available]medium10quinolines
5-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]-1,3-dihydroindol-2-one[no description available]medium10aromatic ketone
ph 797804[no description available]medium10aromatic ether;
benzamides;
organobromine compound;
organofluorine compound;
pyridone		anti-inflammatory agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
srt1720[no description available]medium10
purfalcamine[no description available]medium10
bms 754807[no description available]medium10pyrazoles;
pyridines;
pyrrolidines;
pyrrolotriazine		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
ponatinib[no description available]medium10(trifluoromethyl)benzenes;
acetylenic compound;
benzamides;
imidazopyridazine;
N-methylpiperazine		antineoplastic agent;
tyrosine kinase inhibitor
quizartinib[no description available]medium10benzoimidazothiazole;
isoxazoles;
morpholines;
phenylureas		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
necroptosis inhibitor
PP121[no description available]medium10aromatic amine;
cyclopentanes;
pyrazolopyrimidine;
pyrrolopyridine		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
tyrosine kinase inhibitor
navitoclax[no description available]medium10aryl sulfide;
monochlorobenzenes;
morpholines;
N-sulfonylcarboxamide;
organofluorine compound;
piperazines;
secondary amino compound;
sulfone;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor
gsk 650394[no description available]medium10phenylpyridine
dcc-2036[no description available]medium10organofluorine compound;
phenylureas;
pyrazoles;
pyridinecarboxamide;
quinolines		tyrosine kinase inhibitor
cabozantinib[no description available]medium10aromatic ether;
dicarboxylic acid diamide;
organofluorine compound;
quinolines		antineoplastic agent;
tyrosine kinase inhibitor
TAK-580[no description available]medium101,3-thiazolecarboxamide;
aminopyrimidine;
chloropyridine;
organofluorine compound;
pyrimidinecarboxamide;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
B-Raf inhibitor
8-(4-aminophenyl)-2-(4-morpholinyl)-1-benzopyran-4-one[no description available]medium10chromones
pf 3758309[no description available]medium10organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound
(5-(2,4-bis((3s)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol[no description available]medium10benzyl alcohols;
morpholines;
pyridopyrimidine;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
mTOR inhibitor
5-(2-benzofuranyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine[no description available]medium10aryl sulfide;
thienopyrimidine
5-(3-methylsulfonylphenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine[no description available]medium10aryl sulfide;
thienopyrimidine
5-bromo-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine[no description available]medium10aryl sulfide;
thienopyrimidine
baricitinib[no description available]medium10azetidines;
nitrile;
pyrazoles;
pyrrolopyrimidine;
sulfonamide		anti-inflammatory agent;
antirheumatic drug;
antiviral agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
immunosuppressive agent
6-(1,3-benzodioxol-5-yl)-N-methyl-N-(thiophen-2-ylmethyl)-4-quinazolinamine[no description available]medium10quinazolines
6-[(3-aminophenyl)methyl]-4-methyl-2-methylsulfinyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinone[no description available]medium10organic heterobicyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound
N-[(5-bromo-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamide[no description available]medium10hydroxyquinoline
p505-15[no description available]medium10
mrt67307[no description available]medium10aromatic amine
N-[3-[[5-chloro-2-[4-(4-methyl-1-piperazinyl)anilino]-4-pyrimidinyl]oxy]phenyl]-2-propenamide[no description available]medium10piperazines
ribociclib[no description available]medium10
1-[3-[4-[(1-methyl-5-tetrazolyl)thio]-5-thieno[2,3-d]pyrimidinyl]phenyl]ethanone[no description available]medium10aromatic ketone;
thienopyrimidine
pha 793887[no description available]medium10piperidinecarboxamide
gsk 2334470[no description available]medium10indazoles
ml228 probe[no description available]medium101,2,4-triazines;
biphenyls;
pyridines;
secondary amino compound		hypoxia-inducible factor pathway activator
pf-03882845[no description available]medium10
jq1 compound[no description available]medium10carboxylic ester;
organochlorine compound;
tert-butyl ester;
thienotriazolodiazepine		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
bromodomain-containing protein 4 inhibitor;
cardioprotective agent;
ferroptosis inducer
pf-04620110[no description available]medium10
gsk525762a[no description available]medium10benzodiazepine
birinapant[no description available]medium10dipeptide
torin 1[no description available]medium10N-acylpiperazine;
N-arylpiperazine;
organofluorine compound;
pyridoquinoline;
quinolines		antineoplastic agent;
mTOR inhibitor
abt-199[no description available]medium10aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
N-sulfonylcarboxamide;
oxanes;
pyrrolopyridine		antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor
1-[4-fluoro-3-(trifluoromethyl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)urea[no description available]medium10ureas
N-(4-methyl-2-pyridinyl)-4-[3-(trifluoromethyl)anilino]-1-piperidinecarbothioamide[no description available]medium10(trifluoromethyl)benzenes
ncgc00242364[no description available]medium10quinazolines
gsk1210151a[no description available]medium10imidazoquinoline
hs-173[no description available]medium10
sr1664[no description available]medium10indolecarboxamide
4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-n-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide[no description available]medium10
cudc-907[no description available]medium10
2-[[[4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]-oxomethyl]amino]acetic acid[no description available]medium10quinolines
agi-5198[no description available]medium10
cep-32496[no description available]medium10
epz004777[no description available]medium10N-glycosyl compound
3-[[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)-4-pyrimidinyl]amino]propanoic acid[no description available]medium10organonitrogen heterocyclic compound
entecavir[no description available]medium10benzamides;
N-acylpiperidine
gkt137831[no description available]medium10
vx-509[no description available]medium10
vx-970[no description available]medium10sulfonamide
gs-9973[no description available]medium10
amg 925[no description available]medium10
gne-618[no description available]medium10
g007-lk[no description available]medium10
volitinib[no description available]medium10
ML355[no description available]medium10benzothiazoles;
monomethoxybenzene;
phenols;
secondary amino compound;
substituted aniline;
sulfonamide		EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor;
platelet aggregation inhibitor
acp-196[no description available]medium10aromatic amine;
benzamides;
imidazopyrazine;
pyridines;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary carboxamide;
ynone		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
gsk343[no description available]medium10aminopyridine;
indazoles;
N-alkylpiperazine;
N-arylpiperazine;
pyridone;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitor
agi-6780[no description available]medium10
khs101[no description available]medium10
cb-839[no description available]medium10
gsk-j4[no description available]medium10organonitrogen heterocyclic compound
pf-06424439[no description available]medium10
etp-46464[no description available]medium10
onc201[no description available]medium10
kai407[no description available]medium10
6,7-dimethoxy-2-(pyrrolidin-1-yl)-n-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine[no description available]medium10
enasidenib[no description available]medium101,3,5-triazines;
aminopyridine;
aromatic amine;
organofluorine compound;
secondary amino compound;
tertiary alcohol		antineoplastic agent;
EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor
oicr-9429[no description available]medium10
lly-507[no description available]medium10
at 9283[no description available]medium10
hypoxanthine[no description available]medium10nucleobase analogue;
oxopurine;
purine nucleobase		fundamental metabolite
1-hydroxyphenazine[no description available]medium10phenazines
ro 24-7429[no description available]medium10benzodiazepine
nintedanib[no description available]medium10
n'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthahydrazide[no description available]medium10catechols;
hydrazide;
hydrazone;
naphthols		EC 3.6.5.5 (dynamin GTPase) inhibitor
ver 52296[no description available]medium10aromatic amide;
isoxazoles;
monocarboxylic acid amide;
morpholines;
resorcinols		angiogenesis inhibitor;
antineoplastic agent;
Hsp90 inhibitor
rvx 208[no description available]medium10
bmn 673[no description available]medium10
niacinamide[no description available]medium10pyridine alkaloid;
pyridinecarboxamide;
vitamin B3		anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor
anthralin[no description available]medium10anthracenesantipsoriatic
closantel[no description available]medium10aromatic amide;
monocarboxylic acid amide;
monochlorobenzenes;
nitrile;
organoiodine compound;
phenols
balsalazide[no description available]medium10
fulvestrant[no description available]medium1017beta-hydroxy steroid;
3-hydroxy steroid;
organofluorine compound;
sulfoxide		antineoplastic agent;
estrogen antagonist;
estrogen receptor antagonist
antimycin[no description available]medium10
sulfan blue[no description available]medium10organic molecular entity
acetonitrile[no description available]medium10aliphatic nitrile;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent
formic acid[no description available]medium10monocarboxylic acidantibacterial agent;
astringent;
metabolite;
protic solvent;
solvent
europium[no description available]medium30f-block element atom;
lanthanoid atom
betadex[no description available]medium20cyclodextrin
creatine[no description available]medium20glycine derivative;
guanidines;
zwitterion		geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent;
nutraceutical
lincomycin[no description available]medium71carbohydrate-containing antibiotic;
L-proline derivative;
monocarboxylic acid amide;
pyrrolidinecarboxamide;
S-glycosyl compound		antimicrobial agent;
bacterial metabolite
muramidase[no description available]medium63
sodium sulfite[no description available]medium10inorganic sodium salt;
sulfite salt		food preservative;
reducing agent
potassium permanganate[no description available]medium10
sulfites[no description available]medium10divalent inorganic anion;
sulfur oxide;
sulfur oxoanion
ranitidine[no description available]medium10C-nitro compound;
furans;
organic sulfide;
tertiary amino compound		anti-ulcer drug;
drug allergen;
environmental contaminant;
H2-receptor antagonist;
xenobiotic
sodium hydroxide[no description available]medium10alkali metal hydroxide
cetyltrimethylammonium ion[no description available]medium10quaternary ammonium ion
dibutyl phthalate[no description available]medium10diester;
phthalate ester		EC 3.2.1.20 (alpha-glucosidase) inhibitor;
environmental contaminant;
metabolite;
plasticiser;
teratogenic agent
pyrroles[no description available]medium10pyrrole;
secondary amine
rolitetracycline[no description available]medium90
promethazine[no description available]medium10phenothiazines;
tertiary amine		anti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
sedative
chloroquine[no description available]medium20aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
amphotericin b[no description available]medium50antibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic		antiamoebic agent;
antiprotozoal drug;
bacterial metabolite
paromomycin[no description available]medium20amino cyclitol glycoside;
aminoglycoside antibiotic		anthelminthic drug;
antibacterial drug;
antiparasitic agent;
antiprotozoal drug
uracil[no description available]medium10pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
emepronium[no description available]medium10diarylmethane
ampicillin[no description available]medium205beta-lactam antibiotic;
penicillin allergen;
penicillin		antibacterial drug
oxacillin[no description available]medium60penicillinantibacterial agent;
antibacterial drug
broadcillin[no description available]medium10
beryllium[no description available]medium10alkaline earth metal atom;
elemental beryllium;
metal allergen		adjuvant;
carcinogenic agent;
epitope
aluminum[no description available]medium20boron group element atom;
elemental aluminium;
metal atom
penicillamine[no description available]medium11non-proteinogenic alpha-amino acid;
penicillamine		antirheumatic drug;
chelator;
copper chelator;
drug allergen
titanium[no description available]medium10titanium group element atom
vanadium[no description available]medium10elemental vanadium;
vanadium group element atom		micronutrient
hydrochloric acid[no description available]medium20chlorine molecular entity;
gas molecular entity;
hydrogen halide;
mononuclear parent hydride		mouse metabolite
cephaloridine[no description available]medium81beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug
sulfamethoxazole[no description available]medium32isoxazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
antiinfective agent;
antimicrobial agent;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
epitope;
P450 inhibitor;
xenobiotic
D-fructopyranose[no description available]medium11cyclic hemiketal;
D-fructose;
fructopyranose		sweetening agent
gentamicin[no description available]medium100
amoxicillin[no description available]medium10penicillin allergen;
penicillin		antibacterial drug
glycogen[no description available]medium10
proroxan[no description available]medium10
amphoglucamine[no description available]medium10
metronidazole[no description available]medium10C-nitro compound;
imidazoles;
primary alcohol		antiamoebic agent;
antibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
environmental contaminant;
prodrug;
radiosensitizing agent;
xenobiotic
ristocetin[no description available]medium20glycopeptide;
heterodetic cyclic peptide;
macrocycle;
tetrasaccharide derivative		antibacterial drug;
antimicrobial agent;
bacterial metabolite;
platelet-activating factor receptor agonist
troleandomycin[no description available]medium40acetate ester;
epoxide;
macrolide antibiotic;
monosaccharide derivative;
polyketide;
semisynthetic derivative		EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitor;
xenobiotic
lymecycline[no description available]medium52
cephalothin[no description available]medium50azabicycloalkene;
beta-lactam antibiotic allergen;
carboxylic acid;
cephalosporin;
semisynthetic derivative;
thiophenes		antibacterial drug;
antimicrobial agent
vancomycin[no description available]medium10glycopeptideantibacterial drug;
antimicrobial agent;
bacterial metabolite
rifamycins[no description available]medium10
dihydrostreptomycin sulfate[no description available]medium10
nalidixic acid[no description available]medium501,8-naphthyridine derivative;
monocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antimicrobial agent;
DNA synthesis inhibitor
colistin[no description available]medium60
methenamine[no description available]medium10polyazaalkane;
polycyclic cage;
tetramine		antibacterial drug
sulfamethizole[no description available]medium10sulfonamide antibiotic;
sulfonamide;
thiadiazoles		antiinfective agent;
antimicrobial agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
sucrose[no description available]medium10glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
cycloheximide[no description available]medium10antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor
1-anilino-8-naphthalenesulfonate[no description available]medium10aminonaphthalene;
naphthalenesulfonic acid		fluorescent probe
dactinomycin[no description available]medium10actinomycinmutagen
puromycin[no description available]medium10puromycinsantiinfective agent;
antimicrobial agent;
antineoplastic agent;
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor;
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor;
nucleoside antibiotic;
protein synthesis inhibitor
nitrofurazone[no description available]medium10
cephalosporin c[no description available]medium41cephalosporinfungal metabolite
novobiocin[no description available]medium10carbamate ester;
ether;
hexoside;
hydroxycoumarin;
monocarboxylic acid amide;
monosaccharide derivative;
phenols		antibacterial agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Escherichia coli metabolite;
hepatoprotective agent
carbenicillin[no description available]medium30penicillin allergen;
penicillin		antibacterial drug
erythromycin ethylsuccinate[no description available]medium20cyclic ketone;
erythromycin derivative;
ethyl ester;
succinate ester
biguanides[no description available]medium11guanidines
lysine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
probenecid[no description available]medium10benzoic acids;
sulfonamide		uricosuric drug
dicloxacillin[no description available]medium20dichlorobenzene;
penicillin		antibacterial drug
sulfadimethoxine[no description available]medium10aromatic ether;
pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
drug allergen;
environmental contaminant;
xenobiotic
acetylcysteine[no description available]medium10acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary
glycerol[no description available]medium10alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
guaiacol[no description available]medium10guaiacolsdisinfectant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
expectorant;
plant metabolite
diphenhydramine hydrochloride[no description available]medium10hydrochloride;
organoammonium salt		anti-allergic agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
sedative
sulfamethoxypyridazine[no description available]medium20pyridazines;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
methicillin[no description available]medium20penicillin allergen;
penicillin		antibacterial drug
agar[no description available]medium10
radium[no description available]medium10alkaline earth metal atom
bilirubin[no description available]medium20biladienes;
dicarboxylic acid		antioxidant;
human metabolite;
mouse metabolite
oxazoles[no description available]medium101,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
oxyphenbutazone[no description available]medium10phenols;
pyrazolidines		antimicrobial agent;
antineoplastic agent;
antipyretic;
drug metabolite;
gout suppressant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite
oxymetazoline[no description available]medium10carboxamidine;
imidazolines;
phenols		alpha-adrenergic agonist;
nasal decongestant;
sympathomimetic agent;
vasoconstrictor agent
guaifenesin[no description available]medium10methoxybenzenes
eye[no description available]medium20
ConditionIndicatedRelationship StrengthStudiesTrials
A-alphalipoprotein Neuropathy0low20
Active Hyperemia0low10
Acute Brain Injuries0low10
Acute Kidney Failure0low10
Acute Kidney Injury0low10
Acute Kidney Insufficiency0low10
Acute Renal Failure0low10
Acute Renal Injury0low10
Acute Renal Insufficiency0low10
Adenocarcinoma0low20
Adenocarcinoma Of Kidney0low10
Adenocarcinoma, Basal Cell0low20
Adenocarcinoma, Granular Cell0low20
Adenocarcinoma, Oxyphilic0low20
Adenocarcinoma, Renal0low10
Adenocarcinoma, Renal Cell0low10
Adenocarcinoma, Tubular0low20
Adenoma0low10
Adenoma, Basal Cell0low10
Adenoma, beta-Cell0low10
Adenoma, Follicular0low10
Adenoma, Malignant0low20
Adenoma, Microcystic0low10
Adenoma, Monomorphic0low10
Adenoma, Papillary0low10
Adenoma, Trabecular0low10
Adipocere0low10
Adrenal Cancer0low10
Adrenal Gland Cancer0low10
Adrenal Gland Neoplasms0low10
Adrenal Neoplasm0low10
Affective Psychosis, Bipolar0low10
Aggressive Periodontitis0low10
Aging0low60
Algor Mortis0low10
Allodynia0low10
Allodynia, Mechanical0low10
Allodynia, Tactile0low10
Allodynia, Thermal0low10
Alloxan Diabetes0low90
Alpha High Density Lipoprotein Deficiency Disease0low20
Analphalipoproteinemia0low20
Anoxemia0low10
Anoxia0low10
Anterior Circulation Transient Ischemic Attack0low40
Arrhythmia0low10
Arrhythmias, Cardiac0low10
Arrythmia0low10
Arterial Hyperemia0low10
Arteriosclerosis0low10
Asthma0low10
Asthma, Bronchial0low10
Asymmetric Diabetic Proximal Motor Neuropathy0low30
ATLL0low10
Aura0low10
Autoimmune Diabetes0low10
Awakening Epilepsy0low10
B. burgdorferi Infection0low10
Basophilic Leukemia, Acute0low10
Behavior Disorders0low10
Benign Neoplasms0low70
beta-Cell Tumor0low10
Bipolar Disorder0low10
Bipolar Mood Disorder0low10
Bladder Cancer0low10
Bladder Neoplasms0low10
Bladder Tumors0low10
Blood Pressure, High0low30
Body Weight0low80
Borrelia burgdorferi Infection0low10
Brain Injuries0low10
Brain Injuries, Acute0low10
Brain Injuries, Focal0low10
Brain Ischemia0low20
Brain Lacerations0low10
Brain Stem Ischemia, Transient0low40
Brain Stem Transient Ischemic Attack0low40
Brain TIA0low40
Brainstem Ischemia, Transient0low40
Brainstem Transient Ischemic Attack0low40
Breast Cancer0low20
Breast Carcinoma0low20
Breast Neoplasms0low20
Breast Tumors0low20
Bronchial Asthma0low10
Burns0low20
Cancer0low70
Cancer of Bladder0low10
Cancer of Breast0low20
Cancer of Colon0low90
Cancer of Kidney0low10
Cancer of Liver0low20
Cancer of Lung0low10
Cancer of Ovary0low10
Cancer of Pancreas0low20
Cancer of Pituitary0low40
Cancer of Prostate0low20
Cancer of Skin0low30
Cancer of Stomach0low10
Cancer of the Adrenal Gland0low10
Cancer of the Bladder0low10
Cancer of the Breast0low20
Cancer of the Colon0low90
Cancer of the Kidney0low10
Cancer of the Liver0low20
Cancer of the Lung0low10
Cancer of the Ovary0low10
Cancer of the Pancreas0low20
Cancer of the Pituitary0low40
Cancer of the Prostate0low20
Cancer of the Skin0low30
Cancer of the Stomach0low10
Cancer of the Tongue0low10
Cancer of Tongue0low10
Cancer, Hepatocellular0low20
Carcinoma0low10
Carcinoma, Anaplastic0low10
Carcinoma, Cribriform0low20
Carcinoma, Epidermoid0low40
Carcinoma, Granular Cell0low20
Carcinoma, Hypernephroid0low10
Carcinoma, Planocellular0low40
Carcinoma, Renal Cell0low10
Carcinoma, Spindle-Cell0low10
Carcinoma, Squamous0low40
Carcinoma, Squamous Cell0low40
Carcinoma, Tubular0low20
Carcinoma, Undifferentiated0low10
Carcinomatosis0low10
Cardiac Arrhythmia0low10
Cardiac Arrhythmias0low10
Cardiac Dysrhythmia0low10
Cardiac Failure0low20
Cardiac Hypertrophy0low60
Cardiac Output, Low0low10
Cardiomegaly0low60
Cardiomyopathies0low10
Cardiomyopathies, Primary0low10
Cardiomyopathies, Secondary0low10
Cardiomyopathy, Hypertrophic0low20
Cardiomyopathy, Hypertrophic Obstructive0low20
Cardiovascular Diseases0low10
Carotid Circulation Transient Ischemic Attack0low40
Cell Transformation, Neoplastic0low60
Cell Transformation, Viral0low10
Cerebral Ischemia0low20
Cerebral Ischemia, Transient0low40
Cholesterol Thesaurismosis0low20
Choline Deficiency0low10
Chromophil Renal Cell Carcinoma0low10
Chromophobe Renal Cell Carcinoma0low10
Chromosomal Translocation0low10
Chronic Disease0low10
Chronic Illness0low10
Chronically Ill0low10
Clear Cell Renal Carcinoma0low10
Clear Cell Renal Cell Carcinoma0low10
Cocarcinogenesis0low10
Collecting Duct Carcinoma0low10
Collecting Duct Carcinoma (Kidney)0low10
Collecting Duct Carcinoma of the Kidney0low10
Colon Cancer0low90
Colon Neoplasms0low90
Colonic Cancer0low90
Colonic Neoplasms0low90
Colonic Polyps0low10
Colorectal Cancer0low10
Colorectal Carcinoma0low10
Colorectal Neoplasms0low10
Colorectal Tumors0low10
Condition, Preneoplastic0low10
Conditions, Preneoplastic0low10
Congestive Heart Failure0low20
Coronary Disease0low10
Coronary Heart Disease0low10
Crescendo Transient Ischemic Attacks0low40
Cruor0low10
Cytomegalic Inclusion Disease0low10
Cytomegalovirus Infections0low10
Deficiency, Choline0low10
Deficiency, Oxygen0low10
Degenerative Diseases, Central Nervous System0low10
Degenerative Diseases, Nervous System0low10
Degenerative Diseases, Neurologic0low10
Degenerative Diseases, Spinal Cord0low10
Degenerative Neurologic Diseases0low10
Degenerative Neurologic Disorders0low10
Dementia Praecox0low30
Depression, Bipolar0low10
Di Guglielmo Disease0low10
Di Guglielmo's Disease0low10
Diabetes Mellitus0low30
Diabetes Mellitus, Adult-Onset0medium91
Diabetes Mellitus, Brittle0low10
Diabetes Mellitus, Experimental0low90
Diabetes Mellitus, Insulin-Dependent0low10
Diabetes Mellitus, Insulin-Dependent, 10low10
Diabetes Mellitus, Juvenile-Onset0low10
Diabetes Mellitus, Ketosis-Prone0low10
Diabetes Mellitus, Ketosis-Resistant0medium91
Diabetes Mellitus, Maturity-Onset0medium91
Diabetes Mellitus, Non Insulin Dependent0medium91
Diabetes Mellitus, Non-Insulin-Dependent0medium91
Diabetes Mellitus, Noninsulin Dependent0medium91
Diabetes Mellitus, Noninsulin-Dependent0medium91
Diabetes Mellitus, Slow-Onset0medium91
Diabetes Mellitus, Stable0medium91
Diabetes Mellitus, Sudden-Onset0low10
Diabetes Mellitus, Type 10low10
Diabetes Mellitus, Type 20medium91
Diabetes Mellitus, Type I0low10
Diabetes Mellitus, Type II0medium91
Diabetes, Autoimmune0low10
Diabetic Amyotrophy0low30
Diabetic Angiopathies0low10
Diabetic Asymmetric Polyneuropathy0low30
Diabetic Autonomic Neuropathy0low30
Diabetic Cardiomyopathies0low10
Diabetic Mononeuropathy0low30
Diabetic Mononeuropathy Simplex0low30
Diabetic Neuralgia0low30
Diabetic Neuropathies0low30
Diabetic Neuropathy, Painful0low30
Diabetic Polyneuropathy0low30
Diabetic Vascular Complications0low10
Diabetic Vascular Diseases0low10
Diagnosis, Psychiatric0low10
Disease0low10
Disease Models, Animal0medium81
Early-Onset Periodontitis0low10
Edema-Proteinuria-Hypertension Gestosis0low10
Electrolytes0low10
Elevated Cholesterol0low10
Encephalopathy, Ischemic0low20
Endotoxemia0low10
Enlarged Heart0low60
EPH Complex0low10
EPH Gestosis0low10
EPH Toxemias0low10
Epilepsy0low10
Epilepsy, Cryptogenic0low10
Epithelial Neoplasms, Malignant0low10
Epithelial Tumors, Malignant0low10
Epithelioma0low10
Erythremic Myelosis0low10
Erythroblastic Leukemia, Acute0low10
Erythroleukemia0low10
Experimental Diabetes Mellitus0low90
Experimental Hepatoma0low20
Experimental Hepatomas0low20
Experimental Leukemia0low30
Experimental Leukemias0low30
Experimental Liver Neoplasms0low20
Experimental Mammary Neoplasms0low10
Experimental Neoplasms0low20
Extravascular Hemolysis0low20
Fatty Liver0low110
Fatty Liver, Nonalcoholic0low20
Focal Brain Injuries0low10
Fra(X) Syndrome0low20
Fragile X Mental Retardation Syndrome0low20
Fragile X Syndrome0low20
Fragile X-F Mental Retardation Syndrome0low20
FRAXA Syndrome0low20
FRAXE Syndrome0low20
Gastric Cancer0low10
Gastric Cancer, Familial Diffuse0low10
Gastric Neoplasms0low10
Gastric Stasis0low10
Gastroparesis0low10
Gestosis, EPH0low10
Glial Cell Tumors0low20
Glioma0low20
Glucose Intolerance0low40
Grawitz Tumor0low10
Haemolysis0low20
HDLDT10low20
Heart Decompensation0low20
Heart Disease, Ischemic0low20
Heart Enlargement0low60
Heart Failure0low20
Heart Failure, Congestive0low20
Heart Failure, Left-Sided0low20
Heart Failure, Right-Sided0low20
Heart Hypertrophy0low60
Hemolysis0low20
Hemorrhage, Subarachnoid0low30
Hemorrhagic Thrombocythemia0low10
Hepatic Cancer0low20
Hepatic Neoplasms0low20
Hepatocellular Cancer0low20
Hepatoma, Experimental0low20
Hepatoma, Morris0low20
Hepatoma, Novikoff0low20
Hepatomas, Experimental0low20
High Cholesterol Levels0low10
High Density Lipoprotein Deficiency, Tangier Type0low20
High Density Lipoprotein Deficiency, Type 10low20
High-Density Lipoprotein Deficiency, Tangier Type0low20
High-Density Lipoprotein Deficiency, Type I0low20
HIV0low10
HTLV I Associated T Cell Leukemia Lymphoma0low10
HTLV-Associated Leukemia-Lymphoma0low10
HTLV-I-Associated T-Cell Leukemia-Lymphoma0low10
Human Mammary Carcinoma0low20
Human T Lymphotropic Virus Associated Leukemia Lymphoma0low10
Human T Lymphotropic Virus-Associated Leukemia-Lymphoma0low10
Human T-Cell Leukemia-Lymphoma0low10
Hyperalgesia0low10
Hyperalgesia, Mechanical0low10
Hyperalgesia, Primary0low10
Hyperalgesia, Secondary0low10
Hyperalgesia, Tactile0low10
Hyperalgesia, Thermal0low10
Hyperalgesic Sensations0low10
Hyperalgia0low10
Hyperalgia, Mechanical0low10
Hyperalgia, Primary0low10
Hyperalgia, Secondary0low10
Hypercholesteremia0low10
Hypercholesterolemia0low10
Hyperemia0low10
Hyperglycemia0low20
Hyperglycemia, Postprandial0low20
Hypernephroma0low10
Hypernutrition0low10
Hyperplasia0low10
Hypertension0low30
Hypertension-Edema-Proteinuria Gestosis0low10
Hypertension, Pulmonary0low10
Hypertrophy, Left Ventricular0low10
Hypoxemia0low10
Hypoxia0low10
IDDM0low10
Impaired Glucose Tolerance0low40
Inadequate Sleep0medium11
Inclusion Disease0low10
Infections, Cytomegalovirus0low10
Inflammation0low50
Injuries, Acute Brain0low10
Injuries, Brain0low10
Injury, Ischemia-Reperfusion0low20
Injury, Reperfusion0low20
Innate Inflammatory Response0low50
Insufficient Sleep0medium11
Insufficient Sleep Syndrome0medium11
Insulin Resistance0medium262
Insulin Sensitivity0medium262
Insulin-Dependent Diabetes Mellitus 10low10
Insulinoma0low10
Insuloma0low10
Interstitial Cell Tumor0low10
Intravascular Hemolysis0low20
Ischemia-Reperfusion Injury0low20
Ischemia, Cerebral0low20
Ischemia, Myocardial0low20
Ischemic Attack, Transient0low40
Ischemic Encephalopathy0low20
Ischemic Heart Disease0low20
Juvenile Periodontitis0low10
Juvenile-Onset Diabetes0low10
Kidney Cancer0low10
Kidney Diseases0low10
Kidney Failure, Acute0low10
Kidney Insufficiency, Acute0low10
Kidney Neoplasms0low10
Left Ventricular Dysfunction0low10
Left Ventricular Hypertrophy0low10
Left-Sided Heart Failure0low20
Leukemia L51780low10
Leukemia Lymphoma, Adult T Cell0low10
Leukemia Lymphoma, T Cell, Acute, HTLV I Associated0low10
Leukemia Model, Animal0low30
Leukemia P3880low10
Leukemia-Lymphoma, Adult T-Cell0low10
Leukemia-Lymphoma, T-Cell, Acute, HTLV-I-Associated0low10
Leukemia, Adult T-Cell0low10
Leukemia, Basophilic, Acute0low10
Leukemia, Erythroblastic, Acute0low10
Leukemia, Experimental0low30
Leukemia, Lymphoblastic, Acute, T Cell0low10
Leukemia, Lymphoblastic, Acute, T-Cell0low10
Leukemia, Lymphocytic, Acute T Cell0low10
Leukemia, Lymphocytic, Acute, T-Cell0low10
Leukemia, Megakaryoblastic, Acute0low10
Leukemia, Megakaryocytic0low10
Leukemia, Megakaryocytic, Acute0low10
Leukemia, Myeloid, Acute, M60low10
Leukemia, Myeloid, Acute, M70low10
Leukemia, T-Cell, Acute0low10
Leukemias, Experimental0low30
Leydig Cell Tumor0low10
Lipodystrophy0low10
Lipodystrophy, Intestinal0low10
Liver Cancer0low20
Liver Neoplasms0low20
Liver Neoplasms, Experimental0low20
Liver Steatosis0low110
Livor Mortis0low10
Low Cardiac Output0low10
Low Cardiac Output Syndrome0low10
Lung Cancer0low10
Lung Neoplasms0low10
Lyme Arthritis0low10
Lyme Borreliosis0low10
Lyme Disease0low10
Lymphoblastic Leukemia, Acute, T Cell0low10
Lymphoblastic Leukemia, Acute, T-Cell0low10
Lymphocytic Leukemia, T Cell, Acute0low10
Lymphocytic Leukemia, T-Cell, Acute0low10
Lymphoma L51780low10
Malignancy0low70
Malignant Epithelial Neoplasms0low10
Malignant Glioma0low20
Malignant Neoplasm of Breast0low20
Malignant Neoplasms0low70
Malignant Tumor of Breast0low20
Malignant Tumor of Urinary Bladder0low10
Mammary Cancer0low20
Mammary Carcinoma, Human0low20
Mammary Neoplasm, Human0low20
Mammary Neoplasms, Experimental0low10
Mammary Neoplasms, Human0low20
Manic Depression0low10
Manic Disorder0low10
Manic-Depressive Psychosis0low10
Mar (X) Syndrome0low20
Marker X Syndrome0low20
Martin-Bell Syndrome0low20
Maturity-Onset Diabetes0medium91
Maturity-Onset Diabetes Mellitus0medium91
Mechanical Allodynia0low10
Mechanical Hyperalgesia0low10
Megakaryoblastic Leukemia, Acute0low10
Megakaryocytic Leukemia0low10
Megakaryocytic Leukemia, Acute0low10
Mental Disorders0low10
Mental Disorders, Severe0low10
Mental Illness0low10
Mental Retardation, X-Linked, Associated With Fragile Site Fraxe0low20
Mental Retardation, X-Linked, Associated With Marxq280low20
Microangiopathy, Diabetic0low10
Mixed Glioma0low20
MODY0medium91
Mononeuropathy, Diabetic0low30
Muscle Contraction0low140
Muscular Dystrophies0low10
Muscular Dystrophy0low10
Myeloid Leukemia, Acute, M60low10
Myeloid Leukemia, Acute, M70low10
Myocardial Diseases0low10
Myocardial Diseases, Primary0low10
Myocardial Diseases, Secondary0low10
Myocardial Failure0low20
Myocardial Ischemia0low20
Myocardiopathies0low10
Myodystrophica0low10
Myodystrophy0low10
NAFLD0low20
Necrosis0low20
Neoplasia0low70
Neoplasm0low70
Neoplasms0low70
Neoplasms, Adrenal Gland0low10
Neoplasms, Benign0low70
Neoplasms, Bladder0low10
Neoplasms, Breast0low20
Neoplasms, Colonic0low90
Neoplasms, Colorectal0low10
Neoplasms, Experimental0low20
Neoplasms, Experimental Liver0low20
Neoplasms, Experimental Mammary0low10
Neoplasms, Gastric0low10
Neoplasms, Hepatic0low20
Neoplasms, Kidney0low10
Neoplasms, Liver0low20
Neoplasms, Lung0low10
Neoplasms, Malignant Epithelial0low10
Neoplasms, Ovarian0low10
Neoplasms, Pancreatic0low20
Neoplasms, Prostate0low20
Neoplasms, Prostatic0low20
Neoplasms, Pulmonary0low10
Neoplasms, Skin0low30
Neoplasms, Stomach0low10
Neoplasms, Tongue0low10
Neoplastic Cell Transformation0low60
Neoplastic Transformation, Cell0low60
Nephroid Carcinoma0low10
Nervous System Degenerative Diseases0low10
Neuralgia, Diabetic0low30
Neuroblastoma0low50
Neurodegenerative Diseases0low10
Neurodegenerative Disorders0low10
Neurologic Degenerative Conditions0low10
Neurologic Degenerative Diseases0low10
Neurologic Diseases, Degenerative0low10
Neuropathy of Tangier Disease0low20
Neurovisceral Storage Disease with Vertical Supranuclear Ophthalmoplegia0low10
NIDDM0medium91
Niemann-Pick Disease Type C0low10
Niemann-Pick Disease Type D0low10
Niemann-Pick Disease with Cholesterol Esterification Block0low10
Niemann-Pick Disease without Sphingomyelinase Deficiency0low10
Niemann-Pick Disease, Chronic Neuronopathic Form0low10
Niemann-Pick Disease, Nova Scotian0low10
Niemann-Pick disease, Subacute Juvenile Form0low10
Niemann-Pick Disease, Type C0low10
Niemann-Pick Disease, Type C10low10
Niemann-Pick Disease, Type D0low10
Niemann-Pick Type C Disease0low10
Niemann-Pick Type D Disease0low10
Niemann-Pick's Disease Type C0low10
Niemann-Pick's Disease Type D0low10
Non-alcoholic Fatty Liver Disease0low20
Nonalcoholic Fatty Liver Disease0low20
Nonalcoholic Steatohepatitis0low20
Noninsulin-Dependent Diabetes Mellitus0medium91
Nova Scotia (Type D) Form of Niemann-Pick Disease0low10
Nova Scotia Niemann-Pick Disease (Type D)0low10
Obesity0medium203
Osteogenic Sarcoma0low10
Osteosarcoma0low10
Osteosarcoma Tumor0low10
Ovarian Cancer0low10
Ovarian Neoplasms0low10
Ovary Cancer0low10
Ovary Neoplasms0low10
Overnutrition0low10
Overweight0medium32
Oxygen Deficiency0low10
P388D(1) Leukemia0low10
Pancreas Cancer0low20
Pancreas Neoplasms0low20
Pancreatic Cancer0low20
Pancreatic Neoplasms0low20
Papillary Renal Cell Carcinoma0low10
Passive Hyperemia0low10
Perinatal Subarachnoid Hemorrhage0low30
Periodontitis, Aggressive, 10low10
Periodontitis, Circumpubertal0low10
Periodontitis, Juvenile0low10
Periodontitis, Prepubertal0low10
Periodontosis0low10
Pheochromocytoma0low10
Pheochromocytoma, Extra-Adrenal0low10
Pituitary Adenoma0low40
Pituitary Cancer0low40
Pituitary Carcinoma0low40
Pituitary Neoplasms0low40
Pituitary Tumors0low40
Posterior Circulation Transient Ischemic Attack0low40
Postmortem Changes0low10
Postprandial Hyperglycemia0low20
Pre-Eclampsia0low10
Precancerous Conditions0low10
Precursor T-Cell Lymphoblastic Leukemia0low10
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma0low10
Precursor T-Cell Lymphoblastic Lymphoma0low10
Prediabetes0low10
Prediabetic State0low10
Preeclampsia0low10
Preeclampsia Eclampsia 10low10
Pregnancy0low60
Pregnancy Toxemias0low10
Preneoplastic Condition0low10
Preneoplastic Conditions0low10
Prepubertal Periodontitis0low10
Primary Myocardial Diseases0low10
Primary Thrombocythemia0low10
Prostate Cancer0low20
Prostate Neoplasms0low20
Prostatic Cancer0low20
Prostatic Neoplasms0low20
Proteinuria-Edema-Hypertension Gestosis0low10
Psychiatric Diagnosis0low10
Psychiatric Diseases0low10
Psychiatric Disorders0low10
Psychiatric Illness0low10
Psychoses, Manic-Depressive0low10
Psychosis, Manic-Depressive0low10
Pulmonary Cancer0low10
Pulmonary Hypertension0low10
Pulmonary Neoplasms0low10
Reactive Hyperemia0low10
REM Sleep Deprivation0medium11
Renal Cancer0low10
Renal Carcinoma0low10
Renal Cell Cancer0low10
Renal Cell Carcinoma0low10
Renal Cell Carcinoma, Papillary0low10
Renal Collecting Duct Carcinoma0low10
Renal Failure, Acute0low10
Renal Insufficiency, Acute0low10
Renal Neoplasms0low10
Reperfusion Damage0low20
Reperfusion Injury0low20
Right-Sided Heart Failure0low20
SAH (Subarachnoid Hemorrhage)0low30
Salivary Gland Virus Disease0low10
Sarcoma, Osteogenic0low10
Sarcomatoid Renal Cell Carcinoma0low10
Schizophrenia0low30
Schizophrenic Disorders0low30
Secondary Myocardial Diseases0low10
Seizure Disorder0low10
Sensitivity and Specificity0low20
Skin Cancer0low30
Skin Neoplasms0low30
Sleep Debt0medium11
Sleep Deprivation0medium11
Sleep Fragmentation0medium11
Sleep Insufficiency0medium11
Squamous Cell Carcinoma0low40
Steatohepatitis0low110
Steatosis of Liver0low110
Stomach Cancer0low10
Stomach Neoplasms0low10
Streptozocin Diabetes0low90
Streptozotocin Diabetes0low90
Subarachnoid Hemorrhage0low30
Subarachnoid Hemorrhage, Aneurysmal0low30
Subarachnoid Hemorrhage, Intracranial0low30
Subarachnoid Hemorrhage, Spontaneous0low30
Symmetric Diabetic Proximal Motor Neuropathy0low30
T Cell Leukemia Lymphoma, HTLV I Associated0low10
T Cell Leukemia, Adult0low10
T-ALL0low10
T-Cell Acute Lymphocytic Leukemia0low10
T-Cell Leukemia-Lymphoma, Adult0low10
T-Cell Leukemia-Lymphoma, HTLV-I-Associated0low10
T-Cell Leukemia, Acute0low10
T-Cell Leukemia, Adult0low10
T-Lymphocytic Leukemia, Acute0low10
Tactile Allodynia0low10
Tangier Disease0low20
Tangier Disease Neuropathy0low20
Tangier Hereditary Neuropathy0low20
Thermal Allodynia0low10
Thrombocythemia, Essential0low10
Thrombocythemia, Hemorrhagic0low10
Thrombocythemia, Idiopathic0low10
Thrombocythemia, Primary0low10
Thrombocytosis, Autosomal Dominant0low10
Thrombocytosis, Primary0low10
TIA (Transient Ischemic Attack)0low40
Tongue Cancer0low10
Tongue Neoplasms0low10
Toxemia Of Pregnancy0low10
Toxemias, Pregnancy0low10
Transformation, Neoplastic Cell0low60
Transformation, Viral Cell0low10
Transient Ischemic Attack0low40
Transient Ischemic Attack, Anterior Circulation0low40
Transient Ischemic Attack, Brain Stem0low40
Transient Ischemic Attack, Brainstem0low40
Transient Ischemic Attack, Carotid Circulation0low40
Transient Ischemic Attack, Posterior Circulation0low40
Transient Ischemic Attack, Vertebrobasilar Circulation0low40
Transient Ischemic Attacks, Crescendo0low40
Translocation, Chromosomal0low10
Translocation, Genetic0low10
Tumorigenic Transformation0low60
Tumors0low70
Tumors, Breast0low20
Type 1 Diabetes0low10
Type 1 Diabetes Mellitus0low10
Type 2 Diabetes0medium91
Type 2 Diabetes Mellitus0medium91
Urinary Bladder Cancer0low10
Urinary Bladder Neoplasms0low10
Venous Congestion0low10
Venous Engorgement0low10
Ventricular Dysfunction, Left0low10
Ventricular Hypertrophy, Left0low10
Vertebrobasilar Circulation Transient Ischemic Attack0low40
Viral Cell Transformation0low10
Visceral Steatosis0low110
Weight Gain0low20
Weight Loss0medium11
Weight Reduction0medium11
Whipple Disease0low10
Whipple's Disease0low10
X-Linked Mental Retardation and Macroorchidism0low20
Abortion, Habitual0low20
Abortion, Recurrent0low20
Abortion, Septic0low10
Abortion, Threatened0low10
Abscess, Amebic0low10
Abscess, Pulmonary0low40
Abscesses, Pulmonary0low40
Acanthamebiasis0low10
Acanthamoeba Infection0low10
Acne0low10
Acne Vulgaris0low10
Actinic Reticuloid Syndrome0medium21
Acute Bacterial Prostatitis0medium43
Acute Disease0medium93
Acute Kidney Failure0low20
Acute Kidney Injury0low20
Acute Kidney Insufficiency0low20
Acute Liver Injury, Drug-Induced0low40
Acute Membranous Gingivitis0low10
Acute Necrotizing Ulcerative Gingivitis0low10
Acute Q Fever0low10
Acute Renal Failure0low20
Acute Renal Injury0low20
Acute Renal Insufficiency0low20
Adenoma, Prostatic0low10
Adnexitis0low10
Adverse Drug Event0low10
Adverse Drug Reaction0low10
Age-Related Osteoporosis0low10
Alcohol Abuse0low10
Alcohol Addiction0low10
Alcohol Dependence0low10
Alcohol Use Disorder0low10
Alcoholic Intoxication0low10
Alcoholic Intoxication, Chronic0low10
Alcoholism0low10
Allergy, Drug0low30
Alveolitis, Fibrosing0low10
Amebiasis0low10
Amebiasis, Intestinal0low10
Amebic Dysentery0low10
Ameboma0low10
Amoebiasis0low10
Amoebiasis, Intestinal0low10
Amoebic Colitis0low10
Amoebic Dysentery0low10
Anemia, Aplastic0low10
Anemia, Fanconi0low10
Anemia, Hemolytic0low10
Anemia, Hemolytic, Acquired0low10
Anemia, Hypoplastic0low10
Anemia, Microangiopathic0low10
Angioedema0low10
Angioneurotic Edema0low10
Anuria0low10
Aphthae0low10
Aplastic Anaemia0low10
Aplastic Anemia0low10
Aspergillosis0low10
Aspergillus Infection0low10
Asthma0low20
Asthma, Bronchial0low20
Asymptomatic Inflammatory Prostatitis0medium43
Atelectasis0low10
Atelectasis, Congestive0low10
Atopic Hypersensitivity0low10
Bacterial Disease0medium52
Bacterial Infection0medium52
Bacterial Infections0medium52
Bacteriuria0medium71
Balamuthia Infection0low10
Benign Neoplasms0low10
Benign Prostatic Hyperplasia0low10
Biliary Tract Diseases0low30
Bladder Cancer0low10
Bladder Neoplasms0low10
Bladder Tumors0low10
Blood Poisoning0low50
Blood Protein Disorders0low10
Bloodstream Infection0low50
Body Weight0low30
Bone Diseases0low10
Bone Inflammation0low20
Bone Loss, Age-Related0low10
Bone Loss, Osteoclastic0low10
Bone Resorption0low10
Brain Vascular Disorders0low10
Breast Cancer0low10
Breast Carcinoma0low10
Breast Neoplasms0low10
Breast Tumors0low10
Bronchial Asthma0low20
Bronchial Diseases0low20
Bronchial Neoplasms0medium21
Bronchial Pneumonia0low50
Bronchial Spasm0low20
Bronchiectasis0medium51
Bronchitis0medium237
Bronchopneumonia0low50
Bronchospasm0low20
Brucella Infection0low20
Brucellosis0low20
Brucellosis, Pulmonary0low20
Burkholderia pseudomallei Infection0low10
Cachexia0low10
Cancer0low10
Cancer of Bladder0low10
Cancer of Breast0low10
Cancer of Cervix0low10
Cancer of Larynx0low10
Cancer of Lung0low10
Cancer of Prostate0low20
Cancer of the Bladder0low10
Cancer of the Breast0low10
Cancer of the Cervix0low10
Cancer of the Larynx0low10
Cancer of the Lung0low10
Cancer of the Prostate0low20
Cancer of the Uterine Cervix0low10
Candida Infection0low10
Candidiasis0low10
Canker Sore0low10
Cardiac Failure0low10
Cardiovascular Stroke0low10
Caries, Dental0low10
Carious Dentin0low10
Carious Lesions0low10
Catarrh0low10
Cellulitis0low10
Centriacinar Emphysema0low20
Centrilobular Emphysema0low20
Cerebromeningitis0low10
Cerebrovascular Diseases0low10
Cerebrovascular Disorders0low10
Cerebrovascular Insufficiency0low10
Cerebrovascular Occlusion0low10
Cervical Cancer0low10
Cervical Neoplasms0low10
Cervicitis0low10
Cervix Cancer0low10
Cervix Neoplasms0low10
Chemical and Drug Induced Liver Injury0low40
Chemically-Induced Liver Toxicity0low40
Chlamydia Infections0low40
Cholangitis0low20
Cholecystitis0low40
Cholelithiasis0low10
Cholera Infantum0low10
Chronic Actinic Dermatitis0medium21
Chronic Bacterial Prostatitis0medium43
Chronic Disease0medium188
Chronic Illness0medium188
Chronic Kidney Failure0medium41
Chronic Prostatitis with Chronic Pelvic Pain Syndrome0medium43
Chronic Q Fever0low10
Chronically Ill0medium188
Cold, Common0low10
Colitis0low10
Colitis, Amebic0low10
Common Cold0low10
Communicable Diseases0low20
Complication, Postoperative0medium101
Complications, Infectious Pregnancy0low20
Compression Atelectasis0low10
Compression Pulmonary Atelectasis0low10
Congenital Zika Syndrome0low10
Congenital Zika Virus Infection0low10
Congestive Atelectasis0low10
Congestive Heart Failure0low10
Congestive Pulmonary Atelectasis0low10
Contact Dermatitis0low10
Contraction Pulmonary Atelectasis0low10
Cor Pulmonale0low10
Coryza, Acute0low10
Coxiella burnetii Fever0low10
Coxiella burnetii Infection0low10
Coxiella burnetii Vector-Borne Disease0low10
Cronobacter Infections0low10
Cyprus Fever0low20
Cyst0low10
Cysts0low10
Cytomegalovirus0medium11
Decay, Dental0low10
Deficiency of Glucose-6-Phosphate Dehydrogenase0low10
Deficiency, Glucosephosphate Dehydrogenase0low10
Deficiency, GPD0low10
Deficiency, Vitamin B0low10
Dental Caries0low10
Dental Decay0low10
Dental White Spot0low10
Dental White Spots0low10
Dermatitis Medicamentosa0low20
Dermatitis Seborrheica0low10
Dermatitis Venenata0low10
Dermatitis, Actinic0medium21
Dermatitis, Adverse Drug Reaction0low20
Dermatitis, Contact0low10
Dermatitis, Eczematous0low10
Dermatitis, Seborrheic0low10
Dermatoses0medium31
Dermatosis0medium31
Diarrhea0medium11
Disease Models, Animal0low10
Disease, Pulmonary0medium81
Disease, Pulmonary Heart0low10
Diseases, Pulmonary0medium81
Diseases, Pulmonary Heart0low10
Donovanosis0low20
Drug Allergy0low30
Drug Eruptions0low20
Drug Hypersensitivity0low30
Drug Side Effects0low10
Drug Toxicity0low10
Drug-Induced Acute Liver Injury0low40
Drug-Induced Liver Disease0low40
Drug-Induced Liver Injury0low40
Drug-Induced Stevens Johnson Syndrome0low10
Drug-Induced Stevens-Johnson Syndrome0low10
Drug-Related Side Effects and Adverse Reactions0low10
Drunkenness0low10
Dysentery0low10
Dysentery, Amebic0low10
Dysentery, Bacillary0low10
Dysentery, Shiga bacillus0low10
Dysentery, Shigella boydii0low10
Dysentery, Shigella dysenteriae0low10
Dysentery, Shigella dysenteriae type 10low10
Dysentery, Shigella flexneri0low10
Dysentery, Shigella sonnei0low10
Dysesthesia0medium11
E coli Infections0low70
E. coli Infection0low70
Ear Infection0low10
Ear Inflammation0low10
Eczema0low10
Eczema, Contact0low10
Emesis0medium21
Emphysema, Pulmonary0low20
Emphysemas, Pulmonary0low20
Empyema0medium21
Empyema, Gall Bladder0low40
Empyema, Gallbladder0low40
Encephalomeningitis0low10
End-Stage Kidney Disease0medium41
End-Stage Renal Disease0medium41
Endometritis0low20
Endomyometritis0low20
Endophthalmitis0low10
ENT Diseases0low20
Entamoebiasis, Intestinal0low10
Enteric Fever0low10
Enterobacteriaceae Infections0low10
Enterobacterial Infections0low10
Eperythrozoonosis0low30
Epidermal Necrolysis, Toxic0low10
Escherichia coli Infections0low70
Esophageal Diseases0low10
Esophagitis0low10
ESRD0medium41
Ethanol Abuse0low10
Experimental Lung Inflammation0medium141
Fanconi Anemia0low10
Fanconi Hypoplastic Anemia0low10
Fanconi Pancytopenia0low10
Fanconi Panmyelopathy0low10
Fanconi's Anemia0low10
Female Genital Diseases0low30
Female Genital Neoplasms0low10
Fever0low30
Fever, Zika0low10
Fibroses, Pulmonary0low10
Fibrosis, Pulmonary0low10
Focal Emphysema0low20
Formication0medium11
Functional Gastrointestinal Disorders0low10
Fungal Diseases0low10
Fungal Infections0low10
Fungal Lung Diseases0low10
Fungus Diseases0low10
Fungus Infections0low10
Fusospirillary Gingivitis0low10
Fusospirillosis0low10
G6PD Deficiency0low10
Gallbladder Inflammation0low40
Gallstone Disease0low10
Gastroenteritis0low10
Gastrointestinal Diseases0low10
Gastrointestinal Disorders0low10
Gastrointestinal Disorders, Functional0low10
Gastrointestinal Hemorrhage0low10
Genital Diseases, Female0low30
Genital Neoplasms, Female0low10
Gibraltar Fever0low20
Gingivitis, Necrotizing Ulcerative0low10
Glanders0low10
Glucose 6 Phosphate Dehydrogenase Deficiency0low10
Glucose-6-Phosphate Dehydrogenase Deficiency0low10
Glucosephosphate Dehydrogenase Deficiencies0low10
Glucosephosphate Dehydrogenase Deficiency0low10
Gonorrhea0low160
GPD Deficiency0low10
Granuloma Inguinale0low20
Granuloma Venereum0low20
Grippe0low20
Group A Strep Infection0low40
Group A Streptococcal Infection0low40
Group A Streptococcal Infections0low40
Group B Strep Infection0low40
Group B Streptococcal Infection0low40
Group B Streptococcal Infections0low40
Gynecologic Diseases0low30
Gynecologic Neoplasms0low10
Haemolytic Anaemia0low10
Haemophilus Infections0low10
Haemophilus influenzae Infection0low10
Haemophilus influenzae Type b Infection0low10
Heart Attack0low10
Heart Decompensation0low10
Heart Disease, Pulmonary0low10
Heart Diseases, Pulmonary0low10
Heart Failure0low10
Heart Failure, Congestive0low10
Heart Failure, Left-Sided0low10
Heart Failure, Right-Sided0low10
Hematochezia0low10
Hemolytic Anemia0low10
Hemolytic Anemia Due to G6PD Deficiency0low10
Hemolytic Anemia, Acquired0low10
Hemophilus Infections0low10
Hemorrhage, Gastrointestinal0low10
Hepatitis0low10
Hepatitis, Drug-Induced0low40
Hepatitis, Toxic0low40
Hib Infection0low10
Hives0medium21
Human Flu0low20
Human Influenza0low20
Human Mammary Carcinoma0low10
Hypersensitivity, Atopic0low10
Hypersensitivity, Contact0low10
Hypersensitivity, Drug0low30
Hypersensitivity, Immediate0low10
Hypersensitivity, Type I0low10
Hyperthyroid0low10
Hyperthyroidism0low10
Icterus0low10
Idiopathic Diffuse Interstitial Pulmonary Fibrosis0low10
IgE-Mediated Hypersensitivity0low10
Incontinentia Pigmenti Achromians0low30
Infection0medium173
Infection and Infestation0medium173
Infection, Bacterial0medium52
Infection, Postoperative Wound0low50
Infection, Puerperal0low10
Infection, Surgical Wound0low50
Infections0medium173
Infections and Infestations0medium173
Infections, Bacterial0medium52
Infections, Chlamydia0low40
Infections, E coli0low70
Infections, Enterobacteriaceae0low10
Infections, Enterobacterial0low10
Infections, Escherichia coli0low70
Infections, Haemophilus0low10
Infections, Hemophilus0low10
Infections, Klebsiella0low20
Infections, Mycobacterium0low10
Infections, Mycoplasma0low30
Infections, Pneumococcal0low30
Infections, Proteus0low50
Infections, Pseudomonas0low20
Infections, Respiratory0medium245
Infections, Respiratory Tract0medium245
Infections, Salmonella0low10
Infections, Staphylococcal0medium111
Infections, Streptococcal0low40
Infections, Streptococcus pneumoniae0low30
Infections, Upper Respiratory0medium245
Infections, Upper Respiratory Tract0medium245
Infectious Diarrheal Disease0low10
Infectious Diseases0low20
Infectious Endophthalmitis0low10
Infectious Pregnancy Complications0low20
Infectious Skin Diseases0low10
Inflammation0low20
Inflammatory Disease, Pelvic0low10
Inflammatory Pelvic Disease0low10
Influenza0low20
Influenza in Humans0low20
Influenza, Human0low20
Injuries, Maxillofacial0low10
Innate Inflammatory Response0low20
Interstitial Nephritis0low10
Intestinal Amebiasis0low10
Intestinal Amoebiasis0low10
Intestinal Entamoeba histolytica Infection0low10
Intoxication, Alcoholic0low10
Intracranial Vascular Disorders0low10
Iodamoebiasis0low10
Ito Syndrome0low30
Jaundice0low10
Jaundice, Hemolytic0low10
Jaundice, Spirochetal0low10
Jaw Diseases0medium21
Kidney Diseases0low20
Kidney Failure, Acute0low20
Kidney Failure, Chronic0medium41
Kidney Insufficiency, Acute0low20
Klebsiella Infections0low20
Laryngeal Cancer0low10
Laryngeal Neoplasms0low10
Laryngitis0medium11
Larynx Cancer0low10
Larynx Neoplasms0low10
Left-Sided Heart Failure0low10
Leishmania Infection0low10
Leishmaniasis0low10
Leptospirosis, Icterohemorrhagic0low10
Liver Injury, Drug-Induced0low40
Liver Injury, Drug-Induced, Acute0low40
Lobar Pneumonia0medium141
Lung Abscess0low40
Lung Cancer0low10
Lung Collapse0low10
Lung Diseases0medium81
Lung Diseases, Fungal0low10
Lung Diseases, Parasitic0low10
Lung Inflammation0medium141
Lung Neoplasms0low10
Lyell's Syndrome0low10
Maculopapular Drug Eruption0low20
Maculopapular Exanthem0low20
Malabsorption Syndromes0low10
Malignancy0low10
Malignant Neoplasm of Breast0low10
Malignant Neoplasms0low10
Malignant Tumor of Breast0low10
Malignant Tumor of Urinary Bladder0low10
Malta Fever0low20
Mammary Cancer0low10
Mammary Carcinoma, Human0low10
Mammary Neoplasm, Human0low10
Mammary Neoplasms, Human0low10
Maternal Sepsis0low20
Maxillofacial Injuries0low10
Measles0low20
Melioidosis0low10
Meningitis0low10
Meningoencephalitis0low10
Microangiopathic Hemolytic Anemia0low10
Middle Ear Inflammation0medium21
Miscarriage, Recurrent0low20
Moniliasis0low10
Morbilliform Drug Reaction0low20
Morbilliform Exanthem0low20
Mouth Diseases0medium101
MS (Multiple Sclerosis)0medium11
Mucositis, Oral0low20
Multiple Sclerosis0medium11
Multiple Sclerosis, Acute Fulminating0medium11
Mumps0low10
Mycobacterium Infections0low10
Mycoplasma Infections0low30
Mycoplasma-Induced Stevens Johnson Syndrome0low10
Mycoplasma-Induced Stevens-Johnson Syndrome0low10
Mycoses0low10
Myocardial Failure0low10
Myocardial Infarct0low10
Myocardial Infarction0low10
Nasal Catarrh0low10
Nausea0medium42
Necrotizing Pyelonephritis0low30
Neisseria gonorrhoeae Infection0low160
Neoplasia0low10
Neoplasm0low10
Neoplasms0low10
Neoplasms, Benign0low10
Neoplasms, Bladder0low10
Neoplasms, Breast0low10
Neoplasms, Bronchial0medium21
Neoplasms, Cervical0low10
Neoplasms, Cervix0low10
Neoplasms, Female Genital0low10
Neoplasms, Gynecologic0low10
Neoplasms, Laryngeal0low10
Neoplasms, Lung0low10
Neoplasms, Prostate0low20
Neoplasms, Prostatic0low20
Neoplasms, Pulmonary0low10
Nephritis, Interstitial0low10
Nephritis, Tubulointerstitial0low10
Nonstaphylococcal Scalded Skin Syndrome0low10
Ophthalmia0low10
Oral Mucositis0low20
Orientia tsutsugamushi Infection0low10
Ornithosis0low10
Oromucositis0low20
Osteitis0low20
Osteoclastic Bone Loss0low10
Osteomyelitis0low10
Osteoporosis0low10
Osteoporosis, Age-Related0low10
Osteoporosis, Involutional0low10
Osteoporosis, Post-Traumatic0low10
Osteoporosis, Senile0low10
Otitis0low10
Otitis Media0medium21
Otolaryngologic Diseases0low20
Otolaryngological Diseases0low20
Otorhinolaryngologic Disease0low20
Otorhinolaryngologic Diseases0low20
Otorhinolaryngological Disease0low20
Pachymeningitis0low10
Palmoplantaris Pustulosis0low10
Panacinar Emphysema0low20
Pancytopenia0low10
Panlobular Emphysema0low20
Parasitic Infections of Lung0low10
Parasitic Lung Diseases0low10
Paresthesia0medium11
Paresthesia, Distal0medium11
Paresthesia, Painful0medium11
Parotitis, Epidemic0low10
Pelvic Disease, Inflammatory0low10
Pelvic Inflammatory Disease0low10
Periadenitis Mucosa Necrotica Recurrens0low10
Periapical Cyst0low10
Periapical Periodontitis0medium11
Periodontal Cyst, Apical0low10
Periodontitis, Acute Nonsuppurative0medium11
Periodontitis, Apical0medium11
Phagedenic Gingivitis0low10
Pharyngitis0low20
Phlegmon0low10
Photodermatitis0medium21
Photosensitivity Disorders0medium21
Photosensitization0medium21
Pigmentation Disorders0low30
Pleurisy0low10
Pleuritis0low10
Pneumococcal Diseases0low30
Pneumococcal Infections0low30
Pneumonia0medium141
Pneumonia, Lobar0medium141
Pneumonia, Pneumococcal0low10
Pneumonia, Staphylococcal0low20
Pneumonia, Viral0low20
Pneumonitis0medium141
Poisoning, Blood0low50
Postoperative Complications0medium101
Postoperative Pulmonary Atelectasis0low10
Postoperative Wound Infection0low50
Postpartum Sepsis0low10
Pregnancy0low60
Pregnancy Complications, Infectious0low20
Pregnancy, Infectious Complications0low20
Primary Hyperthyroidism0low10
Prostate Cancer0low20
Prostate Neoplasms0low20
Prostatic Adenoma0low10
Prostatic Cancer0low20
Prostatic Hyperplasia0low10
Prostatic Hyperplasia, Benign0low10
Prostatic Hypertrophy0low10
Prostatic Hypertrophy, Benign0low10
Prostatic Neoplasms0low20
Prostatitis0medium43
Proteus Infections0low50
Pseudomonas aeruginosa Infection0low20
Pseudomonas Infections0low20
Psittacosis0low10
Psoriasis0low10
Puerperal Infection0low10
Pulmonary Abscess0low40
Pulmonary Abscesses0low40
Pulmonary Atelectasis0low10
Pulmonary Cancer0low10
Pulmonary Consumption0medium41
Pulmonary Disease0medium81
Pulmonary Diseases0medium81
Pulmonary Emphysema0low20
Pulmonary Emphysemas0low20
Pulmonary Fibroses0low10
Pulmonary Fibrosis0low10
Pulmonary Fungal Diseases0low10
Pulmonary Fungal Infections0low10
Pulmonary Heart Disease0low10
Pulmonary Heart Diseases0low10
Pulmonary Inflammation0medium141
Pulmonary Neoplasms0low10
Pulmonary Parasitic Infections0low10
Pulmonary Phthisis0medium41
Pulmonary Tuberculoses0medium41
Pulmonary Tuberculosis0medium41
Pus0medium31
Pustular Psoriasis of Palms and Soles0low10
Pustulosis of Palms and Soles0low10
Pustulosis Palmaris et Plantaris0low10
Pyaemia0low50
Pyelonephritis0low30
Pyelonephritis, Acute Necrotizing0low30
Pyemia0low50
Pyohemia0low50
Pyrexia0low30
Q Fever0low10
Query Fever0low10
Quincke's Edema0low10
Radicular Cyst0low10
Recurrent Early Pregnancy Loss0low20
Renal Disease, End-Stage0medium41
Renal Failure, Acute0low20
Renal Failure, Chronic0medium41
Renal Failure, End-Stage0medium41
Renal Insufficiency, Acute0low20
Resorption Atelectasis0low10
Resorption Pulmonary Atelectasis0low10
Respiratory Infections0medium245
Respiratory Tract Diseases0medium51
Respiratory Tract Infections0medium245
Rhinitis0low10
Right-Sided Heart Failure0low10
Rock Fever0low20
Rubeola0low20
Salmonella Infections0low10
Salmonella typhi Infection0low10
Salmonellosis0low10
Scalded Skin Syndrome, Nonstaphylococcal0low10
Schamberg Disease0low30
Schamberg's Disease0low30
Sclerosis, Disseminated0medium11
Scrub Typhus0low10
Seborrhea0low10
Seborrheic Dermatitis0low10
Senile Osteoporosis0low10
Sensitivity and Specificity0low40
Sensitivity, Contact0low10
Sepsis0low50
Sepsis during Pregnancy0low20
Sepsis in Pregnancy0low20
Septic Abortion0low10
Septicemia0low50
Severe Sepsis0low50
Shigella Dysentery0low10
Shigella Infection0low10
Shigellosis0low10
Side Effects of Drugs0low10
Sinus Infections0medium31
Sinusitis0medium31
Skin and Subcutaneous Tissue Disorders0medium31
Skin Diseases0medium31
Skin Diseases, Infectious0low10
Skin Syphilis0low10
Sore Throat0low20
Staphylococcal Infections0medium111
Staphylococcal Pneumonia0low20
Staphylococcus aureus Infection0medium111
Staphylococcus Aureus Pneumonia0low20
Stevens Johnson Syndrome Toxic Epidermal Necrolysis0low10
Stevens Johnson Syndrome Toxic Epidermal Necrolysis Spectrum0low10
Stevens-Johnson Syndrome0low10
Stevens-Johnson Syndrome Toxic Epidermal Necrolysis0low10
Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum0low10
Stomatitis0low20
Stomatitis, Aphthous0low10
Stomatitis, Ulcerative0low10
Streptococcal Infections0low40
Streptococcus pneumoniae Infections0low30
Sunburn0medium11
Suppuration0medium31
Surgical Site Infection0low50
Surgical Wound Infection0low50
Syphilids0low10
Syphilis, Cutaneous0low10
Teeth, Impacted0low20
Thoracic Diseases0medium21
Threatened Miscarriage0low10
Tonsillitis0low30
Tooth Discoloration0low50
Tooth Diseases0medium21
Tooth, Impacted0low20
Toxic Epidermal Necrolysis0low10
Toxic Epidermal Necrolysis Stevens Johnson Syndrome0low10
Toxic Epidermal Necrolysis Stevens Johnson Syndrome Spectrum0low10
Toxic Epidermal Necrolysis Stevens-Johnson Syndrome0low10
Toxic Epidermal Necrolysis Stevens-Johnson Syndrome Spectrum0low10
Toxic Hepatitis0low40
Toxicity, Drug0low10
Trench Mouth0low10
Trichomonas Vaginitis0low10
Trichomoniasis, Human0low10
Tsutsugamushi Disease0low10
Tsutsugamushi Fever0low10
Tuberculoses, Pulmonary0medium41
Tuberculosis, Pulmonary0medium41
Tubulointerstitial Nephritis0low10
Tumors0low10
Tumors, Breast0low10
Type I Hypersensitivity0low10
Typhoid0low10
Typhoid Fever0low10
Typhus, Abdominal0low10
Typhus, Scrub0low10
Ulcer0low20
Ulcer, Aphthous0low10
Undulant Fever0low20
Upper Respiratory Infections0medium245
Upper Respiratory Tract Infection0medium245
Upper Respiratory Tract Infections0medium245
Urethritis0medium61
Urinary Bladder Cancer0low10
Urinary Bladder Neoplasms0low10
Urinary Tract Diseases0low10
Urinary Tract Infections0medium244
Urologic Diseases0low10
Urological Diseases0low10
Urticaria0medium21
Urticaria, Giant0low10
Uterine Cervical Cancer0low10
Uterine Cervical Neoplasms0low10
Uterine Cervicitis0low10
Vascular Diseases, Intracranial0low10
Vincent Angina0low10
Vincent Infection0low10
Vincent's Gingivitis0low10
Vincent's Infection0low10
Vincent's Stomatitis0low10
Vitamin B Deficiency0low10
Vomiting0medium21
Weil Disease0low10
Weil's Disease0low10
White Spot, Dental0low10
White Spots, Dental0low10
Wound Infection, Postoperative0low50
Wound Infection, Surgical0low50
Zika Fever0low10
Zika Virus Disease0low10
Zika Virus Infection0low10
ZikV Infection0low10

Research Highlights

Safety/Toxicity (6)

ArticleYear
Methacycline displays a strong efficacy in reducing toxicity in a SCA3 Caenorhabditis elegans model.
Biochimica et biophysica acta. General subjects, Volume: 1863, Issue: 2		2019
A 90-day repeated-dose toxicity study of dietary alpha linolenic acid-enriched diacylglycerol oil in rats.
Regulatory toxicology and pharmacology : RTP, Volume: 97		2018
Diacylglycerol triggers Rim101 pathway-dependent necrosis in yeast: a model for lipotoxicity.
Cell death and differentiation, Volume: 25, Issue: 4		2018
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
PLoS computational biology, Volume: 7, Issue: 12		2011
Toxicity in a double-blind, placebo-controlled pilot trial with D-penicillamine and metacycline in secondary progressive multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England), Volume: 4, Issue: 2		1998
[Comparative toxicity of oxytetracycline and its semisynthetic derivatives, methacycline and doxycycline].
Antibiotiki, Volume: 23, Issue: 6		1978
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Long-term Use (1)

ArticleYear
Dietary effects of pure and diacylglycerol-rich rice bran oil on growth pattern and lipid profile of rats.
Journal of oleo science, Volume: 61, Issue: 7		2012
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (3)

ArticleYear
Phospholipase C gene expression, protein content, and activities in cardiac hypertrophy and heart failure due to volume overload.
American journal of physiology. Heart and circulatory physiology, Volume: 287, Issue: 2		2004
Implementation of OSPOP, an algorithm for the estimation of optimal sampling times in pharmacokinetics by the ED, EID and API criteria.
Computer methods and programs in biomedicine, Volume: 50, Issue: 1		1996
Application of optimal sampling theory to the determination of metacycline pharmacokinetic parameters: effect of model misspecification.
Journal of pharmacokinetics and biopharmaceutics, Volume: 22, Issue: 2		1994
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (4)

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
Bioorganic & medicinal chemistry, Dec-15, Volume: 15, Issue: 24		2007
Implementation of OSPOP, an algorithm for the estimation of optimal sampling times in pharmacokinetics by the ED, EID and API criteria.
Computer methods and programs in biomedicine, Volume: 50, Issue: 1		1996
Application of optimal sampling theory to the determination of metacycline pharmacokinetic parameters: effect of model misspecification.
Journal of pharmacokinetics and biopharmaceutics, Volume: 22, Issue: 2		1994
[Bioavailability of drug forms of tetracycline-group semisynthetic preparations for internal use].
Antibiotiki, Volume: 28, Issue: 9		1983
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (7)

ArticleYear
Effects of chlorpromazine on the rate of synthesis of various glycerolipids from [3H]glucose in the human primordial placenta.
Acta physiologica Hungarica, Volume: 83, Issue: 2		1995
Activin A inhibits cell-cycle progression induced by insulin-like growth factor-I in Balb/c 3T3 cells.
The Journal of endocrinology, Volume: 137, Issue: 1		1993
Contractile responses and signal transduction of endothelin-1 in aorta and mesenteric vasculature of adult spontaneously hypertensive rats.
Canadian journal of physiology and pharmacology, Volume: 71, Issue: 7		1993
Secretin induces rapid increases in inositol trisphosphate, cytosolic Ca2+ and diacylglycerol as well as cyclic AMP in rat pancreatic acini.
The Biochemical journal, Oct-15, Volume: 239, Issue: 2		1986
The relationship between cytosolic Ca2+, sn-1,2-diacylglycerol and inositol 1,4,5-trisphosphate elevation in platelet-activating-factor-stimulated rabbit platelets. Influence of protein kinase C on production of signal molecules.
The Biochemical journal, Aug-15, Volume: 278 ( Pt 1)		1991
Diacylglycerol accumulation is involved in the potentiating effect of A23187 on carbachol-stimulated amylase secretion from parotid gland.
Research communications in chemical pathology and pharmacology, Volume: 70, Issue: 3		1990
Antibiotics and the Aberdeen typhoid outbreak in 1964.
The Journal of hygiene, Volume: 76, Issue: 2		1976
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]