aminocaproic acid has been researched along with Sensitivity and Specificity in 8 studies
Aminocaproic Acid: An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
6-aminohexanoic acid : An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A specific peptide marker for diagnosing rheumatoid arthritis (RA) was found based on cyclic citrullinated peptide (CCP) using the following three steps: (1) analysis of the binding epitope of autoimmune antibodies using ϵ-aminocaproic acid-modified peptides; (2) RA diagnosis using sequence-modified peptides; and (3) evaluation of the peptides' diagnostic performance for RA diagnosis." | 3.81 | Evaluation of a specific diagnostic marker for rheumatoid arthritis based on cyclic citrullinated peptide. ( Akter, H; Kang, MJ; Nguyen, BT; Park, M; Pyun, JC, 2015) |
| "Hexamethylene bisacetamide (HMBA) is a potent in vitro differentiating agent that has clinical potential as an anticancer drug both as a single agent and as a component of combination therapy." | 1.29 | Simultaneous measurement of the cell-differentiating agent hexamethylene bisacetamide and its metabolites by gas chromatography. ( Chun, HG; Kelley, JA; Roth, JS; Ward, FT, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Park, M | 1 |
| Pyun, JC | 2 |
| Akter, H | 1 |
| Nguyen, BT | 1 |
| Kang, MJ | 1 |
| Reust, DL | 1 |
| Reeves, ST | 1 |
| Abernathy, JH | 1 |
| Dixon, JA | 1 |
| Gaillard, WF | 1 |
| Mukherjee, R | 1 |
| Koval, CN | 1 |
| Stroud, RE | 1 |
| Spinale, FG | 1 |
| Wu, YH | 1 |
| Wu, ML | 1 |
| Lin, CC | 1 |
| Chu, WL | 1 |
| Yang, CC | 1 |
| Lin, RT | 1 |
| Deng, JF | 1 |
| Nahas, DD | 1 |
| Palladino, JS | 1 |
| Joyce, JG | 1 |
| Hepler, RW | 1 |
| Roth, JS | 1 |
| Kelley, JA | 1 |
| Chun, HG | 1 |
| Ward, FT | 1 |
| Cheong, MY | 1 |
| Park, SH | 1 |
| Kim, HY | 1 |
| Park, JS | 1 |
| Fujimoto, T | 1 |
| Nakamura, K | 1 |
| Nishihira, J | 1 |
8 other studies available for aminocaproic acid and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Evaluation of a specific diagnostic marker for rheumatoid arthritis based on cyclic citrullinated peptide.
Topics: Adult; Aged; Aged, 80 and over; Aminocaproic Acid; Arthritis, Rheumatoid; Autoantibodies; Binding Si | 2015 |
Interstitial plasmin activity with epsilon aminocaproic acid: temporal and regional heterogeneity.
Topics: Aminocaproic Acid; Analysis of Variance; Animals; Antifibrinolytic Agents; Area Under Curve; Disease | 2010 |
Determination of caprolactam and 6-aminocaproic acid in human urine using hydrophilic interaction liquid chromatography-tandem mass spectrometry.
Topics: Adult; Aminocaproic Acid; Caprolactam; Chromatography, Liquid; Cimetidine; Drug Interactions; Drug S | 2012 |
Amino acid analysis of peptide loading ratios in conjugate vaccines: a comparison of direct electrochemical detection and 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate pre-column derivatization methods.
Topics: Amino Acids; Aminocaproic Acid; Aminoquinolines; Bacterial Proteins; Carbamates; Chromatography, Hig | 2008 |
Simultaneous measurement of the cell-differentiating agent hexamethylene bisacetamide and its metabolites by gas chromatography.
Topics: Acetamides; Aminocaproates; Aminocaproic Acid; Antineoplastic Agents; Chromatography, Gas; Diethyl P | 1994 |
Modification of short peptides using epsilon-aminocaproic acid for improved coating efficiency in indirect enzyme-linked immunosorbent assays (ELISA).
Topics: Aminocaproic Acid; Autoantigens; Chemical Phenomena; Chemistry, Physical; Chromatography, High Press | 1997 |
Development of a latex immunoturbidimetric assay for the automated measurement of alpha2 plasmin inhibitor-plasmin complex in human plasma.
Topics: alpha-2-Antiplasmin; Aminocaproic Acid; Antibodies, Monoclonal; Antifibrinolytic Agents; Fibrinolysi | 1999 |