Page last updated: 2024-12-05

lignoceric acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Lignoceric acid is a saturated fatty acid with the formula CH3(CH2)22COOH. It is a white, waxy solid that is found in many animal fats and oils. Lignoceric acid is also a component of the myelin sheath, which is a protective layer that surrounds nerve fibers. Research on lignoceric acid has focused on its role in various biological processes, including its potential as a biomarker for certain diseases, its effects on cell membrane fluidity, and its involvement in lipid metabolism. Lignoceric acid can be synthesized through various methods, including the reduction of behenic acid or the oxidation of lignoceryl alcohol. Its importance lies in its contribution to the structural integrity of cell membranes and its involvement in various metabolic pathways. Further studies are needed to fully understand the biological functions of lignoceric acid and its potential therapeutic applications.'

lignoceric acid: RN given refers to parent cpd; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

tetracosanoic acid : A C24 straight-chain saturated fatty acid. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID11197
CHEMBL ID1173620
CHEBI ID28866
SCHEMBL ID132795
MeSH IDM0055542

Synonyms (44)

Synonym
rk3vcw5y1l ,
unii-rk3vcw5y1l
einecs 209-180-7
STL301830
tetracosoic acid
n-tetracosanoic acid
tetraicosanoic acid
tetracosansaeure
CHEBI:28866 ,
tetraeicosanoic acid
ch3-[ch2]22-cooh
lignozerinsaeure
tetracosanic acid
557-59-5
C08320
tetracosanoic acid
lignoceric acid
lignoceric acid, >=99% (capillary gc)
c24:0
carnaubic acid
LMFA01010024
EEF1376B-508E-4043-94E9-AC29747EA6AB
fa 24:0
T0076
CHEMBL1173620
FT-0627855
AKOS015892947
lignoceric acid [mi]
SCHEMBL132795
1219794-61-2
1219794-59-8
tetracosanoic-12,12,13,13-d4 acid
mfcd00002810
DTXSID6021664
F17588
Q422634
AS-48043
tetracosanoic-9,9,10,10-d4 acid
fl 88
HY-121883
tetracosanoicacid
CS-0083602
SY013912
BZV ,

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (4)

RoleDescription
volatile oil componentAny plant metabolite that is found naturally as a component of a volatile oil.
plant metaboliteAny eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
human metaboliteAny mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
Daphnia tenebrosa metaboliteA Daphnia metabolite produced by the species Daphnia tenebrosa.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
very long-chain fatty acidA fatty acid which has a chain length greater than C22. Very long-chain fatty acids which have a chain length greater than C27 are also known as ultra-long-chain fatty acids.
straight-chain saturated fatty acidAny saturated fatty acid lacking a side-chain.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (7)

PathwayProteinsCompounds
Beta Oxidation of Very Long Chain Fatty Acids1013
Adrenoleukodystrophy, X-Linked1013
Carnitine-Acylcarnitine Translocase Deficiency1013
Omega-9 fatty acid synthesis226
Elongation of (very) long chain fatty acids345
AtMetExpress overview0109
Omega-9 and other unsaturated fatty acids biosynthesis pathway017

Bioassays (3)

Assay IDTitleYearJournalArticle
AID492140Antioxidant activity assessed as formazan formation induced absorbance changes at 25 ppm at 570 nm at 37 degC for 6 hrs by MTT assay2010Journal of natural products, Jul-23, Volume: 73, Issue:7
An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.
AID1417295Inhibition of electric eel AChE at 10 M using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured at 1 min intervals for 30 mins by Ellman's method2018Bioorganic & medicinal chemistry letters, 11-01, Volume: 28, Issue:20
Unexpected AChE inhibitory activity of (2E)α,β-unsaturated fatty acids.
AID1417297Inhibition of equine serum BuChE at 10 M using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured at 1 min intervals for 30 mins by Ellman's method2018Bioorganic & medicinal chemistry letters, 11-01, Volume: 28, Issue:20
Unexpected AChE inhibitory activity of (2E)α,β-unsaturated fatty acids.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (169)

TimeframeStudies, This Drug (%)All Drugs %
pre-199044 (26.04)18.7374
1990's43 (25.44)18.2507
2000's35 (20.71)29.6817
2010's43 (25.44)24.3611
2020's4 (2.37)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 46.82

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index46.82 (24.57)
Research Supply Index5.19 (2.92)
Research Growth Index4.52 (4.65)
Search Engine Demand Index72.56 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (46.82)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials3 (1.71%)5.53%
Reviews3 (1.71%)6.00%
Case Studies3 (1.71%)4.05%
Observational0 (0.00%)0.25%
Other166 (94.86%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]