Condition | Indicated | Relationship Strength | Studies | Trials |
Degenerative Diseases, Central Nervous System [description not available] | 0 | 3.7 | 1 | 1 |
Neurodegenerative Diseases Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures. | 0 | 3.7 | 1 | 1 |
Cardiovascular Diseases Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. | 0 | 7.08 | 11 | 3 |
Blood Pressure, High [description not available] | 0 | 4.1 | 5 | 0 |
Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. | 0 | 4.1 | 5 | 0 |
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 5.84 | 8 | 1 |
Diabetes Mellitus A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE. | 0 | 2.74 | 3 | 0 |
Diabetic Retinopathy Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION. | 0 | 2.52 | 2 | 0 |
Electrolytes Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed) | 0 | 2.41 | 1 | 0 |
Cancer of Ovary [description not available] | 0 | 2.52 | 2 | 0 |
Ovarian Neoplasms Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. | 0 | 2.52 | 2 | 0 |
Acute Confusional Senile Dementia [description not available] | 0 | 3.85 | 2 | 1 |
Alzheimer Disease A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) | 0 | 3.85 | 2 | 1 |
Cardiometabolic Syndrome A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components not only include metabolic dysfunctions of METABOLIC SYNDROME but also HYPERTENSION, and ABDOMINAL OBESITY. | 0 | 5.37 | 7 | 0 |
Metabolic Syndrome A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. | 0 | 5.37 | 7 | 0 |
Depression Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders. | 0 | 2.59 | 2 | 0 |
Cancer of Prostate [description not available] | 0 | 4.93 | 8 | 1 |
Prostatic Neoplasms Tumors or cancer of the PROSTATE. | 0 | 4.93 | 8 | 1 |
Colonic Inertia Symptom characterized by the passage of stool once a week or less. | 0 | 2.6 | 1 | 0 |
Constipation Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | 0 | 2.6 | 1 | 0 |
Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. | 0 | 4.52 | 5 | 1 |
Diffuse Mixed Small and Large Cell Lymphoma [description not available] | 0 | 3.51 | 2 | 0 |
Lymphoma, Non-Hodgkin Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease. | 0 | 3.51 | 2 | 0 |
Atherogenesis [description not available] | 0 | 3.76 | 3 | 0 |
Innate Inflammatory Response [description not available] | 0 | 4.41 | 4 | 1 |
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 4.41 | 4 | 1 |
Atherosclerosis A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. | 0 | 3.76 | 3 | 0 |
Disease Resistance The capacity of an organism to defend itself against pathological processes or the agents of those processes. This most often involves innate immunity whereby the organism responds to pathogens in a generic way. The term disease resistance is used most frequently when referring to plants. | 0 | 2.31 | 1 | 0 |
Diabetes Mellitus, Adult-Onset [description not available] | 0 | 5.43 | 7 | 2 |
Diabetes Mellitus, Type 2 A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY. | 0 | 5.43 | 7 | 2 |
Retinal Diseases Diseases involving the RETINA. | 0 | 2.31 | 1 | 0 |
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 5.97 | 5 | 2 |
Overweight A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat. | 0 | 5.03 | 5 | 0 |
Weight Reduction [description not available] | 0 | 3.23 | 1 | 0 |
Obesity A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). | 0 | 7.36 | 9 | 1 |
Weight Loss Decrease in existing BODY WEIGHT. | 0 | 3.23 | 1 | 0 |
Abdominal Obesity [description not available] | 0 | 4.45 | 1 | 1 |
Adolescent Obesity [description not available] | 0 | 4.45 | 1 | 1 |
Colorectal Cancer [description not available] | 0 | 5.27 | 4 | 1 |
Colorectal Neoplasms Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI. | 0 | 5.27 | 4 | 1 |
Deficiency, Vitamin A [description not available] | 0 | 7 | 15 | 0 |
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 8.21 | 13 | 1 |
Vitamin A Deficiency A nutritional condition produced by a deficiency of VITAMIN A in the diet, characterized by NIGHT BLINDNESS and other ocular manifestations such as dryness of the conjunctiva and later of the cornea (XEROPHTHALMIA). Vitamin A deficiency is a very common problem worldwide, particularly in developing countries as a consequence of famine or shortages of vitamin A-rich foods. In the United States it is found among the urban poor, the elderly, alcoholics, and patients with malabsorption. (From Cecil Textbook of Medicine, 19th ed, p1179) | 0 | 7 | 15 | 0 |
Age-Related Macular Degeneration [description not available] | 0 | 2.5 | 2 | 0 |
Macular Degeneration Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms. | 0 | 2.5 | 2 | 0 |
Stunted Growth [description not available] | 0 | 4.48 | 1 | 1 |
Leanness [description not available] | 0 | 4.48 | 1 | 1 |
Growth Disorders Deviations from the average values for a specific age and sex in any or all of the following: height, weight, skeletal proportions, osseous development, or maturation of features. Included here are both acceleration and retardation of growth. | 0 | 4.48 | 1 | 1 |
Cardiac Failure [description not available] | 0 | 2.17 | 1 | 0 |
Heart Failure A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. | 0 | 2.17 | 1 | 0 |
Intertrochanteric Fractures [description not available] | 0 | 2.17 | 1 | 0 |
Hip Fractures Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES). | 0 | 2.17 | 1 | 0 |
Tooth Loss The failure to retain teeth as a result of disease or injury. | 0 | 2.52 | 2 | 0 |
Cancer of Liver [description not available] | 0 | 5.71 | 7 | 1 |
Liver Neoplasms Tumors or cancer of the LIVER. | 0 | 5.71 | 7 | 1 |
Adverse Drug Event [description not available] | 0 | 5.04 | 4 | 0 |
Hypervitaminosis A A symptom complex resulting from ingesting excessive amounts of VITAMIN A. | 0 | 5.04 | 4 | 0 |
Drug-Related Side Effects and Adverse Reactions Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals. | 0 | 5.04 | 4 | 0 |
Bladder Cancer [description not available] | 0 | 2.08 | 1 | 0 |
Urinary Bladder Neoplasms Tumors or cancer of the URINARY BLADDER. | 0 | 2.08 | 1 | 0 |
Cataract, Membranous [description not available] | 0 | 3.35 | 2 | 0 |
Cataract Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed) | 0 | 3.35 | 2 | 0 |
Long Sleeper Syndrome [description not available] | 0 | 2.1 | 1 | 0 |
Sleep Wake Disorders Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle. | 0 | 2.1 | 1 | 0 |
Hepatocellular Carcinoma [description not available] | 0 | 4.52 | 5 | 1 |
Metastase [description not available] | 0 | 2.5 | 2 | 0 |
Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. | 0 | 4.52 | 5 | 1 |
Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 2.5 | 2 | 0 |
Alcohol Drinking Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking. | 0 | 3.61 | 9 | 0 |
Cognition Disorders Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment. | 0 | 5.08 | 5 | 0 |
Idiopathic Parkinson Disease [description not available] | 0 | 3.01 | 1 | 0 |
Parkinson Disease A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) | 0 | 3.01 | 1 | 0 |
Breast Cancer [description not available] | 0 | 9.31 | 20 | 3 |
Breast Neoplasms Tumors or cancer of the human BREAST. | 0 | 9.31 | 20 | 3 |
Cancer of Lung [description not available] | 0 | 5.26 | 12 | 1 |
Lung Neoplasms Tumors or cancer of the LUNG. | 0 | 5.26 | 12 | 1 |
Genetic Predisposition [description not available] | 0 | 2.74 | 3 | 0 |
Dyslipidemia [description not available] | 0 | 2.1 | 1 | 0 |
Deficiency, Vitamin D [description not available] | 0 | 2.1 | 1 | 0 |
Vitamin D Deficiency A nutritional condition produced by a deficiency of VITAMIN D in the diet, insufficient production of vitamin D in the skin, inadequate absorption of vitamin D from the diet, or abnormal conversion of vitamin D to its bioactive metabolites. It is manifested clinically as RICKETS in children and OSTEOMALACIA in adults. (From Cecil Textbook of Medicine, 19th ed, p1406) | 0 | 2.1 | 1 | 0 |
Dyslipidemias Abnormalities in the serum levels of LIPIDS, including overproduction or deficiency. Abnormal serum lipid profiles may include high total CHOLESTEROL, high TRIGLYCERIDES, low HIGH DENSITY LIPOPROTEIN CHOLESTEROL, and elevated LOW DENSITY LIPOPROTEIN CHOLESTEROL. | 0 | 2.1 | 1 | 0 |
Cancer of Stomach [description not available] | 0 | 3.04 | 1 | 0 |
Stomach Neoplasms Tumors or cancer of the STOMACH. | 0 | 3.04 | 1 | 0 |
Carcinoma, Lewis Lung A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy. | 0 | 2.11 | 1 | 0 |
Local Neoplasm Recurrence [description not available] | 0 | 4.68 | 3 | 2 |
Amentia [description not available] | 0 | 2.13 | 1 | 0 |
Dementia An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness. | 0 | 2.13 | 1 | 0 |
Genome Instability [description not available] | 0 | 3.89 | 2 | 1 |
Fatty Liver, Nonalcoholic [description not available] | 0 | 2.13 | 1 | 0 |
Liver Dysfunction [description not available] | 0 | 2.42 | 2 | 0 |
Liver Diseases Pathological processes of the LIVER. | 0 | 2.42 | 2 | 0 |
Non-alcoholic Fatty Liver Disease Fatty liver finding without excessive ALCOHOL CONSUMPTION. | 0 | 2.13 | 1 | 0 |
Elevated Cholesterol [description not available] | 0 | 5.94 | 3 | 3 |
Hypercholesterolemia A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population. | 0 | 5.94 | 3 | 3 |
Cancer of Pancreas [description not available] | 0 | 3.66 | 3 | 0 |
Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA). | 0 | 3.66 | 3 | 0 |
Coxarthrosis [description not available] | 0 | 2.13 | 1 | 0 |
Osteoarthritis, Hip Noninflammatory degenerative disease of the hip joint which usually appears in late middle or old age. It is characterized by growth or maturational disturbances in the femoral neck and head, as well as acetabular dysplasia. A dominant symptom is pain on weight-bearing or motion. | 0 | 2.13 | 1 | 0 |
Arteriosclerosis, Coronary [description not available] | 0 | 3.36 | 2 | 0 |
Coronary Artery Disease Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause. | 0 | 3.36 | 2 | 0 |
Menopause The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age. | 0 | 4.35 | 1 | 1 |
Complications of Diabetes Mellitus [description not available] | 0 | 2.05 | 1 | 0 |
Pericementitis [description not available] | 0 | 2.05 | 1 | 0 |
Periodontitis Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology) | 0 | 2.05 | 1 | 0 |
Chromosomal Translocation [description not available] | 0 | 2.96 | 1 | 0 |
Viral Hepatitis, Human [description not available] | 0 | 3.43 | 1 | 1 |
Cirrhosis, Liver [description not available] | 0 | 4.08 | 3 | 1 |
Hepatitis, Viral, Human INFLAMMATION of the LIVER in humans due to infection by VIRUSES. There are several significant types of human viral hepatitis with infection caused by enteric-transmission (HEPATITIS A; HEPATITIS E) or blood transfusion (HEPATITIS B; HEPATITIS C; and HEPATITIS D). | 0 | 3.43 | 1 | 1 |
Liver Cirrhosis Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. | 0 | 4.08 | 3 | 1 |
Carcinoma, Epidermoid [description not available] | 0 | 3.82 | 2 | 1 |
Cancer of Head [description not available] | 0 | 2.05 | 1 | 0 |
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) | 0 | 3.82 | 2 | 1 |
Head and Neck Neoplasms Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651) | 0 | 2.05 | 1 | 0 |
Muscle Contraction A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. | 0 | 3.44 | 1 | 1 |
Autoimmune Diabetes [description not available] | 0 | 2.47 | 2 | 0 |
Diabetes Mellitus, Type 1 A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. | 0 | 2.47 | 2 | 0 |
Edema-Proteinuria-Hypertension Gestosis [description not available] | 0 | 2.06 | 1 | 0 |
Pregnancy in Diabetes [description not available] | 0 | 2.06 | 1 | 0 |
Pre-Eclampsia A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease. | 0 | 2.06 | 1 | 0 |
Bone Spur [description not available] | 0 | 2.06 | 1 | 0 |
Osteophytosis, Spinal [description not available] | 0 | 2.06 | 1 | 0 |
Breast Diseases Pathological processes of the BREAST. | 0 | 3.8 | 2 | 1 |
Heart Disease, Ischemic [description not available] | 0 | 2.72 | 3 | 0 |
Myocardial Ischemia A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION). | 0 | 2.72 | 3 | 0 |
Disease Exacerbation [description not available] | 0 | 2.73 | 3 | 0 |
Parodontosis [description not available] | 0 | 2.08 | 1 | 0 |
Periodontal Diseases Pathological processes involving the PERIODONTIUM including the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT. | 0 | 2.08 | 1 | 0 |
Abnormalities, Autosome [description not available] | 0 | 3.47 | 1 | 1 |
Polyps Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base. | 0 | 2.1 | 1 | 0 |
Eye Disorders [description not available] | 0 | 3.4 | 1 | 1 |
Eye Diseases Diseases affecting the eye. | 0 | 3.4 | 1 | 1 |
Coronary Heart Disease [description not available] | 0 | 4.87 | 4 | 0 |
Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. | 0 | 4.87 | 4 | 0 |
Cardiovascular Stroke [description not available] | 0 | 3.79 | 2 | 0 |
Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). | 0 | 3.79 | 2 | 0 |
Chronic Primary Open Angle Glaucoma [description not available] | 0 | 2.01 | 1 | 0 |
Glaucoma, Open-Angle Glaucoma in which the angle of the anterior chamber is open and the trabecular meshwork does not encroach on the base of the iris. | 0 | 2.01 | 1 | 0 |
Arteriosclerosis Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries. | 0 | 3.84 | 4 | 0 |
Aura [description not available] | 0 | 3.4 | 1 | 1 |
Epilepsy A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) | 0 | 3.4 | 1 | 1 |
Weight Gain Increase in BODY WEIGHT over existing weight. | 0 | 4.09 | 3 | 1 |
Infection [description not available] | 0 | 2.02 | 1 | 0 |
Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases. | 0 | 2.02 | 1 | 0 |
Infections, Respiratory [description not available] | 0 | 3.4 | 1 | 1 |
Acute Disease Disease having a short and relatively severe course. | 0 | 4.32 | 4 | 1 |
Respiratory Tract Infections Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases. | 0 | 3.4 | 1 | 1 |
Cancer of Skin [description not available] | 0 | 4.07 | 3 | 1 |
Skin Neoplasms Tumors or cancer of the SKIN. | 0 | 4.07 | 3 | 1 |
Apolipoprotein B-100, Familial Defective [description not available] | 0 | 2.02 | 1 | 0 |
Hyperlipoproteinemia Type II A group of familial disorders characterized by elevated circulating cholesterol contained in either LOW-DENSITY LIPOPROTEINS alone or also in VERY-LOW-DENSITY LIPOPROTEINS (pre-beta lipoproteins). | 0 | 2.02 | 1 | 0 |
Cerebral Ischemia [description not available] | 0 | 2.02 | 1 | 0 |
Brain Ischemia Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION. | 0 | 2.02 | 1 | 0 |
Airway Obstruction Any hindrance to the passage of air into and out of the lungs. | 0 | 2.03 | 1 | 0 |
Insulin Sensitivity [description not available] | 0 | 2.03 | 1 | 0 |
Insulin Resistance Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS. | 0 | 2.03 | 1 | 0 |
Chronic Illness [description not available] | 0 | 2.71 | 3 | 0 |
Angor Pectoris [description not available] | 0 | 2.03 | 1 | 0 |
Angina Pectoris The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION. | 0 | 2.03 | 1 | 0 |
Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 2.71 | 3 | 0 |
Cancer of Mouth [description not available] | 0 | 2.03 | 1 | 0 |
Condition, Preneoplastic [description not available] | 0 | 2.41 | 2 | 0 |
Mouth Neoplasms Tumors or cancer of the MOUTH. | 0 | 2.03 | 1 | 0 |
Precancerous Conditions Pathological conditions that tend eventually to become malignant. | 0 | 2.41 | 2 | 0 |
Cell Transformation, Neoplastic Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill. | 0 | 3.79 | 2 | 1 |
Cancer of Colon [description not available] | 0 | 5.2 | 6 | 2 |
Colonic Neoplasms Tumors or cancer of the COLON. | 0 | 5.2 | 6 | 2 |
Adenoma, Basal Cell [description not available] | 0 | 4.64 | 3 | 2 |
Adenoma A benign epithelial tumor with a glandular organization. | 0 | 4.64 | 3 | 2 |
Porphyria Cutanea Tarda An autosomal dominant or acquired porphyria due to a deficiency of UROPORPHYRINOGEN DECARBOXYLASE in the LIVER. It is characterized by photosensitivity and cutaneous lesions with little or no neurologic symptoms. Type I is the acquired form and is strongly associated with liver diseases and hepatic toxicities caused by alcohol or estrogenic steroids. Type II is the familial form. | 0 | 1.98 | 1 | 0 |
Benign Neoplasms [description not available] | 0 | 4.05 | 3 | 1 |
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 4.05 | 3 | 1 |
Alcohol Abuse [description not available] | 0 | 1.98 | 1 | 0 |
Alcoholism A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4) | 0 | 1.98 | 1 | 0 |
Cancer of Cervix [description not available] | 0 | 1.98 | 1 | 0 |
Uterine Cervical Neoplasms Tumors or cancer of the UTERINE CERVIX. | 0 | 1.98 | 1 | 0 |
Carcinoma, Oat Cell [description not available] | 0 | 1.98 | 1 | 0 |
Carcinoma, Small Cell An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7) | 0 | 1.98 | 1 | 0 |
Anasarca [description not available] | 0 | 1.98 | 1 | 0 |
Edema Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE. | 0 | 1.98 | 1 | 0 |
Alcoholic Cirrhosis [description not available] | 0 | 1.98 | 1 | 0 |
Liver Cirrhosis, Alcoholic FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING. | 0 | 1.98 | 1 | 0 |
Tracheal Neoplasms New abnormal growth of tissue in the TRACHEA. | 0 | 1.99 | 1 | 0 |
Cancer of Endometrium [description not available] | 0 | 1.98 | 1 | 0 |
Endometrial Neoplasms Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells. | 0 | 1.98 | 1 | 0 |
Plasmodium falciparum Malaria [description not available] | 0 | 2.4 | 2 | 0 |
Malaria, Falciparum Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations. | 0 | 2.4 | 2 | 0 |
Cancer of Rectum [description not available] | 0 | 2.4 | 2 | 0 |
Rectal Neoplasms Tumors or cancer of the RECTUM. | 0 | 2.4 | 2 | 0 |
Experimental Neoplasms [description not available] | 0 | 1.99 | 1 | 0 |
Adenocarcinoma, Basal Cell [description not available] | 0 | 2.69 | 3 | 0 |
Adenocarcinoma A malignant epithelial tumor with a glandular organization. | 0 | 2.69 | 3 | 0 |
Hepatitis B Virus Infection [description not available] | 0 | 1.99 | 1 | 0 |
Hepatitis B INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact. | 0 | 1.99 | 1 | 0 |
Hyperlipemia [description not available] | 0 | 1.99 | 1 | 0 |
Hyperlipidemias Conditions with excess LIPIDS in the blood. | 0 | 1.99 | 1 | 0 |
Experimental Radiation Injuries [description not available] | 0 | 1.99 | 1 | 0 |
Cystic Fibrosis of Pancreas [description not available] | 0 | 3.79 | 2 | 1 |
Cystic Fibrosis An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION. | 0 | 3.79 | 2 | 1 |
HIV Coinfection [description not available] | 0 | 4.3 | 1 | 1 |
HIV Infections Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS). | 0 | 4.3 | 1 | 1 |
Birth Weight The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms. | 0 | 1.99 | 1 | 0 |
Congenital Fissure of the Abdominal Cavity [description not available] | 0 | 1.99 | 1 | 0 |
Gastroschisis A congenital defect with major fissure in the ABDOMINAL WALL lateral to, but not at, the UMBILICUS. This results in the extrusion of VISCERA. Unlike OMPHALOCELE, herniated structures in gastroschisis are not covered by a sac or PERITONEUM. | 0 | 1.99 | 1 | 0 |
Impaired Glucose Tolerance [description not available] | 0 | 2 | 1 | 0 |
Glucose Intolerance A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION. | 0 | 2 | 1 | 0 |
Adenomatous Polyps Benign neoplasms derived from glandular epithelium. (From Stedman, 25th ed) | 0 | 2 | 1 | 0 |
Colonic Polyps Discrete tissue masses that protrude into the lumen of the COLON. These POLYPS are connected to the wall of the colon either by a stalk, pedunculus, or by a broad base. | 0 | 2 | 1 | 0 |
Intestinal Polyps Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base. | 0 | 2 | 1 | 0 |
ALS - Amyotrophic Lateral Sclerosis [description not available] | 0 | 3.38 | 1 | 1 |
Amyotrophic Lateral Sclerosis A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) | 0 | 8.38 | 1 | 1 |
Arterial Diseases, Carotid [description not available] | 0 | 2 | 1 | 0 |
Carotid Artery Diseases Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology. | 0 | 2 | 1 | 0 |
Pancreatic Insufficiency [description not available] | 0 | 2 | 1 | 0 |
Exocrine Pancreatic Insufficiency A malabsorption condition resulting from greater than 10% reduction in the secretion of pancreatic digestive enzymes (LIPASE; PROTEASES; and AMYLASE) by the EXOCRINE PANCREAS into the DUODENUM. This condition is often associated with CYSTIC FIBROSIS and with chronic PANCREATITIS. | 0 | 2 | 1 | 0 |
Erythema Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes. | 0 | 3.39 | 1 | 1 |
Experimental Hepatoma [description not available] | 0 | 2 | 1 | 0 |
Invasiveness, Neoplasm [description not available] | 0 | 2 | 1 | 0 |
MS (Multiple Sclerosis) [description not available] | 0 | 2 | 1 | 0 |
Multiple Sclerosis An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) | 0 | 7 | 1 | 0 |
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 2 | 1 | 0 |
Parasitemia The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed) | 0 | 2 | 1 | 0 |
Papilloma, Squamous Cell [description not available] | 0 | 1.98 | 1 | 0 |
Papilloma A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed) | 0 | 1.98 | 1 | 0 |
Neuroblastoma A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) | 0 | 6.97 | 1 | 0 |