Proteins > corticotropin-releasing hormone receptor 2
Page last updated: 2024-08-07 18:22:04

corticotropin-releasing hormone receptor 2

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (91)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
fluorometholoneHomo sapiens (human)IC5047.100010
methazolamideHomo sapiens (human)IC5047.100010
1,4-bis(2-(3,5-dichloropyridyloxy))benzeneHomo sapiens (human)IC509.184020
sulfachlorpyridazineHomo sapiens (human)IC5047.100010
2-nitrotolueneHomo sapiens (human)IC5047.100010
3,4,5-trichlorophenolHomo sapiens (human)IC5014.545020
nilvermHomo sapiens (human)IC5047.100010
(1-hydroxycyclopentyl)phenylacetic acidHomo sapiens (human)IC5047.100010
dibenzo-27-crown-9Homo sapiens (human)IC5013.970020
1-(1,3-benzodioxol-5-yl)-3-(1-piperidinyl)-1-propanoneHomo sapiens (human)IC5047.100010
5-chloro-1,3-dihydro-2h-benzimidazol-2-oneHomo sapiens (human)IC5047.100010
LSM-22807Homo sapiens (human)IC506.580020
5,5-dioxo-1-(4-phenoxyphenyl)-3a,4,6,6a-tetrahydro-3H-thieno[3,4-b]pyrrol-2-oneHomo sapiens (human)IC5047.100010
4-methyl-N-[3-[1-(phenylmethyl)-4-piperidinyl]-2,4-dihydro-1H-1,3,5-triazin-6-yl]benzenesulfonamideHomo sapiens (human)IC5047.100010
2-[2-(ethylthio)-1-benzimidazolyl]-1-(1-piperidinyl)ethanoneHomo sapiens (human)IC5047.100010
1-(3-cyano-7-methoxy-2-quinolinyl)-4-piperidinecarboxylic acid ethyl esterHomo sapiens (human)IC5047.100010
N-(3-methoxyphenyl)-1-[4-(1-tetrazolyl)phenyl]sulfonyl-3-piperidinecarboxamideHomo sapiens (human)IC5047.100010
1-[5-(2-amino-5-methyl-4-thiazolyl)-2,3-dihydroindol-1-yl]-1-butanoneHomo sapiens (human)IC5047.100010
2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]-1-(4-phenyl-1-piperazinyl)ethanoneHomo sapiens (human)IC5047.100010
fludarabineHomo sapiens (human)IC5047.100010
3-(2-ethoxy-6-methyl-3-pyridinyl)-5-(2-pyridinyl)-1,2,4-oxadiazoleHomo sapiens (human)IC5047.100010
3-[(3aR,6aS)-6'-chloro-5-(4-chlorophenyl)-7'-methyl-2',4,6-trioxo-1-spiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]yl]propanamideHomo sapiens (human)IC5047.100010
4-(1-benzotriazolyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidineHomo sapiens (human)IC5047.100010
3-cyclohexyl-1,1-bis(2-methylpropyl)thioureaHomo sapiens (human)IC5047.100010
5-(2,4-dichlorophenyl)-N-(2-methylphenyl)-2-furancarboxamideHomo sapiens (human)IC5047.100010
2-(thiophen-2-ylmethylidene)indene-1,3-dioneHomo sapiens (human)IC5047.100010
5-(methoxymethyl)-2-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-oneHomo sapiens (human)IC5047.100010
2-methoxy-4-[[2-(methylthio)anilino]methyl]phenolHomo sapiens (human)IC5047.100010
5,6-dichloro-4-(4-methylphenyl)-1H-pyrazine-2,3-dioneHomo sapiens (human)IC5047.100010
4-[[[[oxo-(4-phenylphenyl)methyl]amino]-sulfanylidenemethyl]amino]benzoic acidHomo sapiens (human)IC505.985020
2-[acetyl(2-furanylmethyl)amino]-N-(4-chlorophenyl)-5-methyl-4-thiazolecarboxamideHomo sapiens (human)IC5047.100010
N-(5-chloro-2-hydroxyphenyl)-1,3-dimethyl-2-oxo-5-benzimidazolesulfonamideHomo sapiens (human)IC5047.100010
4,5-dimethoxy-2-[[1-oxo-2-[(3,5,8-trimethyl-2-quinolinyl)thio]ethyl]amino]benzoic acidHomo sapiens (human)IC5015.050020
5-(3,3-dimethyl-2-oxobutoxy)-3,4,7-trimethyl-1-benzopyran-2-oneHomo sapiens (human)IC5047.100010
6-methyl-5-phenyl-2-(phenylthio)-3-pyridinecarbonitrileHomo sapiens (human)IC5010.184020
4-[4-(2,4-dichlorophenyl)-2-thiazolyl]benzoic acidHomo sapiens (human)IC5011.910020
5-cyano-2-phenyl-6-[4-(2-pyridinyl)-1-piperazinyl]-3-pyridinecarboxylic acid ethyl esterHomo sapiens (human)IC5047.100010
3-(benzenesulfonyl)-2-imino-1-propyl-5-dipyrido[1,2-d-3',4'-f]pyrimidinoneHomo sapiens (human)IC5047.100010
N-[3-(2-methoxyphenyl)-1-methyl-4-oxo-2-quinolinyl]-2-methylpropanamideHomo sapiens (human)IC5047.100010
N-(2-acetylphenyl)-2-(2-oxo-1-quinoxalinyl)acetamideHomo sapiens (human)IC5047.100010
5-methoxy-3-methyl-N-(3-methylbutyl)-2-benzofurancarboxamideHomo sapiens (human)IC5047.100010
2-[[2-[[5-(4-tert-butylphenyl)-2-methoxycarbonyl-3-thiophenyl]amino]-2-oxoethyl]thio]acetic acidHomo sapiens (human)IC509.100020
N-(4-bromo-3-chlorophenyl)-5-oxo-1-propan-2-yl-3-pyrrolidinecarboxamideHomo sapiens (human)IC5047.100010
N-[3-chloro-4-[4-[oxo-(4-propoxyphenyl)methyl]-1-piperazinyl]phenyl]propanamideHomo sapiens (human)IC5016.150020
2-[(3-cyano-4,6-diphenyl-2-pyridinyl)thio]-3-methylbutanoic acidHomo sapiens (human)IC5013.380020
1-(3,5-dimethyl-1-piperidinyl)-2-[[2-(thiophen-2-ylmethyl)-4-quinazolinyl]thio]ethanoneHomo sapiens (human)IC504.903330
N-[2-(cyclopentylamino)-2-oxoethyl]-4,7-dimethyl-N-(2-methylphenyl)-2-oxo-3H-pyrido[1,2-a]pyrimidine-4-carboxamideHomo sapiens (human)IC5047.100010
3-chloro-N-(5-chloro-2-pyridinyl)-4-ethoxybenzamideHomo sapiens (human)IC5047.100010
3-(4-chlorophenyl)-2-(1-pyrrolidinyl)-4-quinazolinoneHomo sapiens (human)IC5047.100010
benzoic acid [[1-(4-nitrophenyl)-4-piperidinylidene]amino] esterHomo sapiens (human)IC5014.246720
4-(4-methylphenyl)sulfonyl-3-phenyl-2,3-dihydro-1,4-benzoxazineHomo sapiens (human)IC5010.184020
3-amino-4-[(4-chlorophenyl)thio]benzoic acid methyl esterHomo sapiens (human)IC5010.184020
clothiapineHomo sapiens (human)IC5047.100010
indocyanine greenHomo sapiens (human)IC5047.100010
2-[3-(3-chlorophenyl)-5-isoxazolyl]-1-hydroxy-4H-1,2,4-benzotriazin-3-oneHomo sapiens (human)IC5047.100010
macelignanHomo sapiens (human)IC5047.100010
guvacine hydrochlorideHomo sapiens (human)IC5047.100010
amorfrutin aHomo sapiens (human)IC5010.015020
2-[[4-(5-chloro-2-methoxyanilino)-6-(1-piperidinyl)-1,3,5-triazin-2-yl]amino]ethanolHomo sapiens (human)IC5047.100010
(7R,13S)-6-[(2S)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(4R)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-10-(2-methoxyethoxymethoxyimino)-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-oneHomo sapiens (human)IC5047.100010
6-(3-chloroanilino)-9-cyclopentyl-2-purinecarbonitrileHomo sapiens (human)IC5047.100010
MMP-9-IN-1Homo sapiens (human)IC5047.100010

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
fluorometholoneHomo sapiens (human)EC5053.000010
methazolamideHomo sapiens (human)EC5053.000010
1,4-bis(2-(3,5-dichloropyridyloxy))benzeneHomo sapiens (human)EC5053.000010
sulfachlorpyridazineHomo sapiens (human)EC5053.000010
2-nitrotolueneHomo sapiens (human)EC5053.000010
3,4,5-trichlorophenolHomo sapiens (human)EC5053.000010
3-aminofluorantheneHomo sapiens (human)EC504.790010
1-(piperidinomethyl)-2-naphtholHomo sapiens (human)EC5011.920020
pentamethylmelamineHomo sapiens (human)EC5053.000010
nilvermHomo sapiens (human)EC5053.000010
(1-hydroxycyclopentyl)phenylacetic acidHomo sapiens (human)EC5053.000010
bis-a-tdaHomo sapiens (human)EC5053.000010
dibenzo-27-crown-9Homo sapiens (human)EC5015.400010
1-(1,3-benzodioxol-5-yl)-3-(1-piperidinyl)-1-propanoneHomo sapiens (human)EC5053.000010
5-chloro-1,3-dihydro-2h-benzimidazol-2-oneHomo sapiens (human)EC5053.000010
LSM-22807Homo sapiens (human)EC5012.500010
5,5-dioxo-1-(4-phenoxyphenyl)-3a,4,6,6a-tetrahydro-3H-thieno[3,4-b]pyrrol-2-oneHomo sapiens (human)EC5053.000010
4-methyl-N-[3-[1-(phenylmethyl)-4-piperidinyl]-2,4-dihydro-1H-1,3,5-triazin-6-yl]benzenesulfonamideHomo sapiens (human)EC5053.000010
2-[2-(ethylthio)-1-benzimidazolyl]-1-(1-piperidinyl)ethanoneHomo sapiens (human)EC5053.000010
1-(3-cyano-7-methoxy-2-quinolinyl)-4-piperidinecarboxylic acid ethyl esterHomo sapiens (human)EC5053.000010
N-(3-methoxyphenyl)-1-[4-(1-tetrazolyl)phenyl]sulfonyl-3-piperidinecarboxamideHomo sapiens (human)EC5053.000010
1-[5-(2-amino-5-methyl-4-thiazolyl)-2,3-dihydroindol-1-yl]-1-butanoneHomo sapiens (human)EC5053.000010
2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]-1-(4-phenyl-1-piperazinyl)ethanoneHomo sapiens (human)EC5053.000010
fludarabineHomo sapiens (human)EC5053.000010
6,6,7-trimethyl-1-(4-morpholinyl)-3-(phenylmethylthio)-5,8-dihydro-2,7-naphthyridine-4-carbonitrileHomo sapiens (human)EC5053.000010
2-(2-ethyl-1-piperidinyl)-1-(2-methyl-1H-indol-3-yl)ethanoneHomo sapiens (human)EC5022.600010
5-(4-methoxyphenyl)-7-(4-methylphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidineHomo sapiens (human)EC5053.000010
3-(2-ethoxy-6-methyl-3-pyridinyl)-5-(2-pyridinyl)-1,2,4-oxadiazoleHomo sapiens (human)EC5053.000010
3-[(3aR,6aS)-6'-chloro-5-(4-chlorophenyl)-7'-methyl-2',4,6-trioxo-1-spiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]yl]propanamideHomo sapiens (human)EC5053.000010
4-(1-benzotriazolyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidineHomo sapiens (human)EC5053.000010
3-cyclohexyl-1,1-bis(2-methylpropyl)thioureaHomo sapiens (human)EC5053.000010
5-(2,4-dichlorophenyl)-N-(2-methylphenyl)-2-furancarboxamideHomo sapiens (human)EC5053.000010
2-(thiophen-2-ylmethylidene)indene-1,3-dioneHomo sapiens (human)EC5053.000010
5-(methoxymethyl)-2-phenyl-1H-pyrazolo[1,5-a]pyrimidin-7-oneHomo sapiens (human)EC5053.000010
3-[(6-methyl-4-phenyl-2-quinazolinyl)amino]propanoic acidHomo sapiens (human)EC5012.650020
6-methyl-4-(trifluoromethyl)-7,8,9,10-tetrahydropyrano[2,3-f]quinolin-2-oneHomo sapiens (human)EC501.120010
2-methoxy-4-[[2-(methylthio)anilino]methyl]phenolHomo sapiens (human)EC5053.000010
N-[(4-fluoroanilino)-sulfanylidenemethyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamideHomo sapiens (human)EC5053.000010
5,6-dichloro-4-(4-methylphenyl)-1H-pyrazine-2,3-dioneHomo sapiens (human)EC5053.000010
4-[[[[oxo-(4-phenylphenyl)methyl]amino]-sulfanylidenemethyl]amino]benzoic acidHomo sapiens (human)EC5053.000010
2-[acetyl(2-furanylmethyl)amino]-N-(4-chlorophenyl)-5-methyl-4-thiazolecarboxamideHomo sapiens (human)EC5053.000010
N-(5-chloro-2-hydroxyphenyl)-1,3-dimethyl-2-oxo-5-benzimidazolesulfonamideHomo sapiens (human)EC5053.000010
4,5-dimethoxy-2-[[1-oxo-2-[(3,5,8-trimethyl-2-quinolinyl)thio]ethyl]amino]benzoic acidHomo sapiens (human)EC5053.000010
5-(3,3-dimethyl-2-oxobutoxy)-3,4,7-trimethyl-1-benzopyran-2-oneHomo sapiens (human)EC5053.000010
1-[1-ethyl-6-methyl-4-(4-phenyl-1-piperazinyl)-2-sulfanylidene-5-pyrimidinyl]ethanoneHomo sapiens (human)EC5053.000010
2-(4-bromophenoxy)-N-[(2-hydroxy-5-methylanilino)-sulfanylidenemethyl]acetamideHomo sapiens (human)EC507.000010
6-methyl-5-phenyl-2-(phenylthio)-3-pyridinecarbonitrileHomo sapiens (human)EC5053.000010
4-[4-(2,4-dichlorophenyl)-2-thiazolyl]benzoic acidHomo sapiens (human)EC5053.000010
5-cyano-2-phenyl-6-[4-(2-pyridinyl)-1-piperazinyl]-3-pyridinecarboxylic acid ethyl esterHomo sapiens (human)EC5053.000010
3-(benzenesulfonyl)-2-imino-1-propyl-5-dipyrido[1,2-d-3',4'-f]pyrimidinoneHomo sapiens (human)EC5053.000010
2-[2-[[1-oxo-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)thio]ethyl]amino]-4-thiazolyl]acetic acid ethyl esterHomo sapiens (human)EC5053.000010
5-bromo-N-[[[oxo(thiophen-2-yl)methyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamideHomo sapiens (human)EC5012.200010
N-[3-(2-methoxyphenyl)-1-methyl-4-oxo-2-quinolinyl]-2-methylpropanamideHomo sapiens (human)EC5053.000010
N-[4-[[2-[1-(2-methoxyethyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl]thio]phenyl]acetamideHomo sapiens (human)EC5053.000010
N-[[(1-oxo-3-phenylpropyl)hydrazo]-sulfanylidenemethyl]pentanamideHomo sapiens (human)EC504.320010
N-(2-acetylphenyl)-2-(2-oxo-1-quinoxalinyl)acetamideHomo sapiens (human)EC5053.000010
5-methoxy-3-methyl-N-(3-methylbutyl)-2-benzofurancarboxamideHomo sapiens (human)EC5053.000010
5-(4-(dimethylamino)benzylidene)rhodanineHomo sapiens (human)EC504.780010
2-(1-adamantylcarbonyl)hydrazine-1-carbothioamideHomo sapiens (human)EC503.530010
4-oxo-2-(trifluoromethyl)-1H-thieno[3,4-b]pyridine-7-carboxylic acid methyl esterHomo sapiens (human)EC505.750010
2-[[2-[[5-(4-tert-butylphenyl)-2-methoxycarbonyl-3-thiophenyl]amino]-2-oxoethyl]thio]acetic acidHomo sapiens (human)EC5036.800010
4-chloro-N-[2-(4-morpholinyl)cyclohexyl]benzenesulfonamideHomo sapiens (human)EC5013.700010
N-(4-bromo-3-chlorophenyl)-5-oxo-1-propan-2-yl-3-pyrrolidinecarboxamideHomo sapiens (human)EC5053.000010
N-[3-chloro-4-[4-[oxo-(4-propoxyphenyl)methyl]-1-piperazinyl]phenyl]propanamideHomo sapiens (human)EC5053.000010
2-(4-chloro-2-methylphenoxy)-N-[2-(4-morpholinyl)phenyl]propanamideHomo sapiens (human)EC506.000010
2-[(3-cyano-4,6-diphenyl-2-pyridinyl)thio]-3-methylbutanoic acidHomo sapiens (human)EC5035.700010
1-(3,5-dimethyl-1-piperidinyl)-2-[[2-(thiophen-2-ylmethyl)-4-quinazolinyl]thio]ethanoneHomo sapiens (human)EC5053.000010
N-[2-(cyclopentylamino)-2-oxoethyl]-4,7-dimethyl-N-(2-methylphenyl)-2-oxo-3H-pyrido[1,2-a]pyrimidine-4-carboxamideHomo sapiens (human)EC5053.000010
3-chloro-N-(5-chloro-2-pyridinyl)-4-ethoxybenzamideHomo sapiens (human)EC5053.000010
3-(4-chlorophenyl)-2-(1-pyrrolidinyl)-4-quinazolinoneHomo sapiens (human)EC5053.000010
N-(4-methoxyphenyl)-2-(N-methylanilino)-2-(6-nitro-1,3-benzodioxol-5-yl)acetamideHomo sapiens (human)EC5053.000010
7-(5-bromo-2-fluorophenyl)-5-(4-bromophenyl)-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidineHomo sapiens (human)EC5053.000010
benzoic acid [[1-(4-nitrophenyl)-4-piperidinylidene]amino] esterHomo sapiens (human)EC5053.000010
4-(4-methylphenyl)sulfonyl-3-phenyl-2,3-dihydro-1,4-benzoxazineHomo sapiens (human)EC5053.000010
N-(5-phenyl-1,3,4-oxadiazol-2-yl)-1,3-benzothiazole-2-carboxamideHomo sapiens (human)EC507.070010
1-benzoyl-5-hydroxy-5-(4-methylphenyl)-4H-pyrazole-3-carboxylic acid ethyl esterHomo sapiens (human)EC5013.500010
3-amino-4-[(4-chlorophenyl)thio]benzoic acid methyl esterHomo sapiens (human)EC5053.000010
2-(4-benzoylphenoxy)-N-[4-(propan-2-ylsulfamoyl)phenyl]propanamideHomo sapiens (human)EC504.600010
clothiapineHomo sapiens (human)EC5053.000010
indocyanine greenHomo sapiens (human)EC5053.000010
N-(4,7-dimethyl-1,3-benzothiazol-2-yl)-4-(2,5-dioxo-1-pyrrolidinyl)benzamideHomo sapiens (human)EC5053.000010
alpha-solanineHomo sapiens (human)EC509.480010
2-[3-(3-chlorophenyl)-5-isoxazolyl]-1-hydroxy-4H-1,2,4-benzotriazin-3-oneHomo sapiens (human)EC5013.160020
macelignanHomo sapiens (human)EC5053.000010
guvacine hydrochlorideHomo sapiens (human)EC5053.000010
amorfrutin aHomo sapiens (human)EC5035.200010
2-[[4-(5-chloro-2-methoxyanilino)-6-(1-piperidinyl)-1,3,5-triazin-2-yl]amino]ethanolHomo sapiens (human)EC5053.000010
(7R,13S)-6-[(2S)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(4R)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-10-(2-methoxyethoxymethoxyimino)-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-oneHomo sapiens (human)EC5053.000010
6-(3-chloroanilino)-9-cyclopentyl-2-purinecarbonitrileHomo sapiens (human)EC5053.000010
N-[3-[(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)amino]-1-isoindolylidene]-2-thiophenecarboxamideHomo sapiens (human)EC505.980010
MMP-9-IN-1Homo sapiens (human)EC5053.000010