A protein that is a translation product of the Slc6a12 gene in rat. [PRO:DNx, UniProtKB:P48056]
Na(+)/Cl(-) betaine/GABA transporter;
Solute carrier family 6 member 12
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| gamma-aminobutyric acid | Rattus norvegicus (Norway rat) | IC50 | 0.0200 | 1 | 1 |
| 2,4-diaminobutyric acid | Rattus norvegicus (Norway rat) | IC50 | 2.0000 | 1 | 1 |
| 4,5,6,7-tetrahydroisoxazolo(4,5-c)pyridin-3-ol | Rattus norvegicus (Norway rat) | IC50 | 116.0000 | 2 | 2 |
| diclofenac | Rattus norvegicus (Norway rat) | IC50 | 0.5000 | 1 | 1 |
| indomethacin | Rattus norvegicus (Norway rat) | IC50 | 0.2000 | 1 | 1 |
| muscimol | Rattus norvegicus (Norway rat) | IC50 | 0.0032 | 1 | 1 |
| masoprocol | Rattus norvegicus (Norway rat) | IC50 | 30.0000 | 1 | 1 |
| propofol | Rattus norvegicus (Norway rat) | IC50 | 8.3000 | 1 | 1 |
| pf 5901 | Rattus norvegicus (Norway rat) | IC50 | 300.0000 | 1 | 1 |
| phenidone | Rattus norvegicus (Norway rat) | IC50 | 3.0000 | 1 | 1 |
| pregnanolone | Rattus norvegicus (Norway rat) | IC50 | 0.1170 | 1 | 1 |
| nafazatrom | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| bw-755c | Rattus norvegicus (Norway rat) | IC50 | 5.0000 | 1 | 1 |
| 2(3h)-benzofuranone | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| minaxolone | Rattus norvegicus (Norway rat) | IC50 | 0.0710 | 1 | 1 |
| 1-benzyl-1h-indazol-3-ol | Rattus norvegicus (Norway rat) | IC50 | 31.0000 | 1 | 1 |
| 3-indazolinone | Rattus norvegicus (Norway rat) | IC50 | 30.0000 | 1 | 1 |
| brexanolone | Rattus norvegicus (Norway rat) | IC50 | 0.0910 | 1 | 1 |
| tetrahydrodeoxycorticosterone | Rattus norvegicus (Norway rat) | IC50 | 0.2200 | 1 | 1 |
| alphaxalone | Rattus norvegicus (Norway rat) | IC50 | 0.5380 | 1 | 1 |
| 5,6,7,8-tetrahydro-4h-isoxazolo(4,5-d)azepin-3-ol | Rattus norvegicus (Norway rat) | IC50 | 300.0000 | 1 | 1 |
| thiopental | Rattus norvegicus (Norway rat) | IC50 | 29.5000 | 1 | 1 |
| isothaz | Rattus norvegicus (Norway rat) | IC50 | 300.0000 | 1 | 1 |
| quercetin | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| baicalein | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |