60 kDa chaperonin

Timeframe	Studies on this Protein(%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	5 (83.33)	24.3611
2020's	1 (16.67)	2.80

Timeframe

Studies on this Protein(%)

All Drugs %

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

5 (83.33)

24.3611

2020's

1 (16.67)

2.80

Compounds (64)

Drugs with Inhibition Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
4-nonylphenol	Escherichia coli	IC50	20.5000	2	2
albuterol	Escherichia coli	IC50	175.0000	2	2
aurintricarboxylic acid	Escherichia coli	IC50	0.7350	2	2
benzbromarone	Escherichia coli	IC50	33.5000	2	2
bithionol	Escherichia coli	IC50	8.6500	2	2
candesartan	Escherichia coli	IC50	175.0000	2	2
eflornithine	Escherichia coli	IC50	175.0000	2	2
dichlorophen	Escherichia coli	IC50	45.0000	2	2
ethacrynic acid	Escherichia coli	IC50	4.9500	2	2
harmalol	Escherichia coli	IC50	58.0000	2	2
hexachlorophene	Escherichia coli	IC50	3.0500	2	2
beta-lapachone	Escherichia coli	IC50	0.9450	2	2
vitamin k 3	Escherichia coli	IC50	5.7500	2	2
mesalamine	Escherichia coli	IC50	3.2450	2	2
pentamidine	Escherichia coli	IC50	175.0000	2	2
primaquine	Escherichia coli	IC50	40.6000	2	2
protoporphyrin ix	Escherichia coli	IC50	3.7000	2	2
cetrimonium bromide	Escherichia coli	IC50	9.2500	2	2
ampicillin	Escherichia coli	IC50	100.0000	2	2
purpurin	Escherichia coli	IC50	9.5000	2	2
salicylanilide	Escherichia coli	IC50	100.0000	2	2
benzanilide	Escherichia coli	IC50	100.0000	2	2
benzethonium chloride	Escherichia coli	IC50	25.0000	2	2
evans blue	Escherichia coli	IC50	0.0630	2	2
lithocholic acid	Escherichia coli	IC50	37.5000	2	2
plumbagin	Escherichia coli	IC50	2.0450	2	2
gentian violet	Escherichia coli	IC50	13.0000	2	2
erythromycin	Escherichia coli	IC50	139.0000	2	2
agaric acid	Escherichia coli	IC50	6.2000	2	2
ethidium bromide	Escherichia coli	IC50	51.2000	2	2
vancomycin	Escherichia coli	IC50	100.0000	2	2
cetylpyridinium chloride	Escherichia coli	IC50	6.5500	2	2
rafoxanide	Escherichia coli	IC50	3.2500	2	2
paclitaxel	Escherichia coli	IC50	85.0000	2	2
closantel	Escherichia coli	IC50	1.9750	4	4
adapalene	Escherichia coli	IC50	3.6000	2	2
epigallocatechin gallate	Escherichia coli	IC50	0.4700	2	2
sb 204070a	Escherichia coli	IC50	175.0000	2	2
gossypol acetic acid	Escherichia coli	IC50	0.5450	2	2
tretinoin	Escherichia coli	IC50	13.8500	2	2
arachidonic acid	Escherichia coli	IC50	12.6500	2	2
riboflavin	Escherichia coli	IC50	59.0000	2	2
4'-methoxychalcone	Escherichia coli	IC50	21.5000	2	2
4-chloro-3-nitro-1-(phenylmethyl)-2-quinolinone	Escherichia coli	IC50	99.8143	7	7
curcumin	Escherichia coli	IC50	3.0000	2	2
gossypetin	Escherichia coli	IC50	1.2450	2	2
vitamin d 2	Escherichia coli	IC50	34.5000	2	2
cholecalciferol	Escherichia coli	IC50	26.5000	2	2
morin	Escherichia coli	IC50	6.8500	2	2
4-hydroxychalcone	Escherichia coli	IC50	30.5000	2	2
4'-hydroxychalcone	Escherichia coli	IC50	38.5000	2	2
phenoxybenzamine hydrochloride	Escherichia coli	IC50	84.5000	2	2
nalbuphine	Escherichia coli	IC50	175.0000	2	2
nifuroxazide	Escherichia coli	IC50	59.5000	4	4
22,23-dihydroavermectin b(1)a	Escherichia coli	IC50	16.2500	2	2
avermectin b(1)a	Escherichia coli	IC50	20.9000	2	2
nitrofurantoin	Escherichia coli	IC50	75.7500	4	4
nifurtimox	Escherichia coli	IC50	175.0000	2	2
erythrosine	Escherichia coli	IC50	0.8500	2	2
tannins	Escherichia coli	IC50	0.9350	2	2
ly-146032	Escherichia coli	IC50	100.0000	2	2
6-o-palmitoylascorbic acid	Escherichia coli	IC50	6.0000	2	2
rifampin	Escherichia coli	IC50	100.0000	2	2
hematein	Escherichia coli	IC50	1.5000	2	2

Drug

Taxonomy

Measurement

Average (mM)

Bioassay(s)

Publication(s)

4-nonylphenol

Escherichia coli

IC50

20.5000

albuterol

Escherichia coli

IC50

175.0000

aurintricarboxylic acid

Escherichia coli

IC50

0.7350

benzbromarone

Escherichia coli

IC50

33.5000

bithionol

Escherichia coli

IC50

8.6500

candesartan

Escherichia coli

IC50

175.0000

eflornithine

Escherichia coli

IC50

175.0000

dichlorophen

Escherichia coli

IC50

45.0000

ethacrynic acid

Escherichia coli

IC50

4.9500

harmalol

Escherichia coli

IC50

58.0000

hexachlorophene

Escherichia coli

IC50

3.0500

beta-lapachone

Escherichia coli

IC50

0.9450

vitamin k 3

Escherichia coli

IC50

5.7500

mesalamine

Escherichia coli

IC50

3.2450

pentamidine

Escherichia coli

IC50

175.0000

primaquine

Escherichia coli

IC50

40.6000

protoporphyrin ix

Escherichia coli

IC50

3.7000

cetrimonium bromide

Escherichia coli

IC50

9.2500

ampicillin

Escherichia coli

IC50

100.0000

purpurin

Escherichia coli

IC50

9.5000

salicylanilide

Escherichia coli

IC50

100.0000

benzanilide

Escherichia coli

IC50

100.0000

benzethonium chloride

Escherichia coli

IC50

25.0000

evans blue

Escherichia coli

IC50

0.0630

lithocholic acid

Escherichia coli

IC50

37.5000

plumbagin

Escherichia coli

IC50

2.0450

gentian violet

Escherichia coli

IC50

13.0000

erythromycin

Escherichia coli

IC50

139.0000

agaric acid

Escherichia coli

IC50

6.2000

ethidium bromide

Escherichia coli

IC50

51.2000

vancomycin

Escherichia coli

IC50

100.0000

cetylpyridinium chloride

Escherichia coli

IC50

6.5500

rafoxanide

Escherichia coli

IC50

3.2500

paclitaxel

Escherichia coli

IC50

85.0000

closantel

Escherichia coli

IC50

1.9750

adapalene

Escherichia coli

IC50

3.6000

epigallocatechin gallate

Escherichia coli

IC50

0.4700

sb 204070a

Escherichia coli

IC50

175.0000

gossypol acetic acid

Escherichia coli

IC50

0.5450

tretinoin

Escherichia coli

IC50

13.8500

arachidonic acid

Escherichia coli

IC50

12.6500

riboflavin

Escherichia coli

IC50

59.0000

4'-methoxychalcone

Escherichia coli

IC50

21.5000

4-chloro-3-nitro-1-(phenylmethyl)-2-quinolinone

Escherichia coli

IC50

99.8143

curcumin

Escherichia coli

IC50

3.0000

gossypetin

Escherichia coli

IC50

1.2450

vitamin d 2

Escherichia coli

IC50

34.5000

cholecalciferol

Escherichia coli

IC50

26.5000

morin

Escherichia coli

IC50

6.8500

4-hydroxychalcone

Escherichia coli

IC50

30.5000

4'-hydroxychalcone

Escherichia coli

IC50

38.5000

phenoxybenzamine hydrochloride

Escherichia coli

IC50

84.5000

nalbuphine

Escherichia coli

IC50

175.0000

nifuroxazide

Escherichia coli

IC50

59.5000

22,23-dihydroavermectin b(1)a

Escherichia coli

IC50

16.2500

avermectin b(1)a

Escherichia coli

IC50

20.9000

nitrofurantoin

Escherichia coli

IC50

75.7500

nifurtimox

Escherichia coli

IC50

175.0000

erythrosine

Escherichia coli

IC50

0.8500

tannins

Escherichia coli

IC50

0.9350

ly-146032

Escherichia coli

IC50

100.0000

6-o-palmitoylascorbic acid

Escherichia coli

IC50

6.0000

rifampin

Escherichia coli

IC50

100.0000

hematein

Escherichia coli

IC50

1.5000

GroEL/ES inhibitors as potential antibiotics.
Bioorganic & medicinal chemistry letters, , 07-01, Volume: 26, Issue:13, 2016

A biochemical screen for GroEL/GroES inhibitors.
Bioorganic & medicinal chemistry letters, , Feb-01, Volume: 24, Issue:3, 2014

Synonyms

Research

Bioassay Publications (6)

Compounds (64)

Drugs with Inhibition Measurements