Page last updated: 2024-08-07 15:31:33
Phospholipase A2, major isoenzyme
A phospholipase A2 that is encoded in the genome of pig. [OMA:P00592, PRO:DNx]
Synonyms
EC 3.1.1.4;
Group IB phospholipase A2;
Phosphatidylcholine 2-acylhydrolase 1B
Research
Bioassay Publications (8)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
Compounds (8)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| indomethacin | Sus scrofa (pig) | IC50 | 1,000.0000 | 1 | 1 |
| ketoconazole | Sus scrofa (pig) | IC50 | 1,000.0000 | 1 | 1 |
| lonapalene | Sus scrofa (pig) | IC50 | 1,000.0000 | 1 | 1 |
| varespladib | Sus scrofa (pig) | IC50 | 0.0480 | 2 | 2 |
| ly 311727 | Sus scrofa (pig) | IC50 | 6.4940 | 4 | 5 |
| 2-(phenylmethyl)-1-naphthol | Sus scrofa (pig) | IC50 | 1,000.0000 | 1 | 1 |
| bolinaquinone | Sus scrofa (pig) | IC50 | 0.4000 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| phenidone | Sus scrofa (pig) | Activity | 300.0000 | 1 | 1 |