Proteins > Sigma intracellular receptor 2
Page last updated: 2024-08-07 20:40:38
Sigma intracellular receptor 2
A sigma intracellular receptor 2 that is encoded in the genome of rat. [PRO:DNx]
Synonyms
Sigma-2 receptor;
Sigma2 receptor;
Transmembrane protein 97
Research
Bioassay Publications (27)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (33.33) | 24.3611 |
| 2020's | 18 (66.67) | 2.80 |
Compounds (36)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| gw 7647 | Rattus norvegicus (Norway rat) | EC50 | 0.0050 | 1 | 1 |
| gft505 | Rattus norvegicus (Norway rat) | EC50 | 0.2250 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| 5-methylsalicylic acid | Rattus norvegicus (Norway rat) | INH | 100.0000 | 1 | 1 |
[no title available]European journal of medicinal chemistry, , Feb-15, Volume: 230, 2022
Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation.European journal of medicinal chemistry, , Feb-15, Volume: 230, 2022
Development of tumor-targeting aza-vesamicol derivatives with high affinity for sigma receptors for cancer theranostics.RSC medicinal chemistry, , Aug-17, Volume: 13, Issue:8, 2022
[no title available]Journal of medicinal chemistry, , 09-22, Volume: 65, Issue:18, 2022
Synthesis of 8-aminomorphans with high KOR affinity.European journal of medicinal chemistry, , Feb-15, Volume: 230, 2022
Synthesis and biological evaluation of conformationally restricted GluN2B ligands derived from eliprodil.European journal of medicinal chemistry, , Jul-05, Volume: 237, 2022
[no title available]European journal of medicinal chemistry, , Jul-05, Volume: 219, 2021
[no title available]European journal of medicinal chemistry, , Jan-01, Volume: 209, 2021
[no title available]RSC medicinal chemistry, , Jun-23, Volume: 12, Issue:6, 2021
Novel σEuropean journal of medicinal chemistry, , Jan-15, Volume: 210, 2021
[no title available]European journal of medicinal chemistry, , Mar-15, Volume: 190, 2020
[no title available]European journal of medicinal chemistry, , Feb-15, Volume: 230, 2022
[no title available]Journal of medicinal chemistry, , 09-22, Volume: 65, Issue:18, 2022
Synthesis and biological evaluation of conformationally restricted GluN2B ligands derived from eliprodil.European journal of medicinal chemistry, , Jul-05, Volume: 237, 2022
[no title available]European journal of medicinal chemistry, , Jul-05, Volume: 219, 2021
Novel σEuropean journal of medicinal chemistry, , Jan-15, Volume: 210, 2021
Synthesis and RSC medicinal chemistry, , Mar-04, Volume: 12, Issue:2, 2021
Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation.European journal of medicinal chemistry, , Feb-15, Volume: 230, 2022
Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σEuropean journal of medicinal chemistry, , Jan-15, Volume: 228, 2022