pirenzepine has been researched along with Sensitivity and Specificity in 17 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bethanechol induced smooth muscle contractions via muscarinic receptor subtype M3." | 3.74 | Corticotropin-releasing factor inhibition of sheep fetal colonic contractility: mechanisms to prevent meconium passage in utero. ( Ahanya, SA; Lakshmanan, J; Liu, G; Mazdak, M; Oyachi, N; Ross, MG, 2007) |
| "Pirenzepine was considered as a pharmacologic agent of preventing form-deprivation myopia." | 1.33 | HPLC determination of pirenzepine dihydrochloride in rabbit aqueous humor. ( Li, P; Pang, H; Tu, J; Yang, X, 2005) |
| "The degree of lipemia of each sample, indicated by turbidity, was ranked into categories from least to greatest and used for statistical analyses." | 1.32 | A study of matrix effects on an LC/MS/MS assay for olanzapine and desmethyl olanzapine. ( Chin, C; Karnes, HT; Zhang, ZP, 2004) |
| "Ziprasidone (Zeldox) is a novel antipsychotic with a unique combination of antagonist activities at monoaminergic receptors and transporters and potent agonist activity at serotonin 5-HT(1A) receptors." | 1.31 | 5-HT(1A) receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex. ( Lu, Y; Rollema, H; Schmidt, AW; Sprouse, JS; Zorn, SH, 2000) |
| "Olanzapine is a commonly used atypical antipsychotic medication for which therapeutic drug monitoring has been proposed as clinically useful." | 1.31 | A high-performance liquid chromatography assay with ultraviolet detection for olanzapine in human plasma and urine. ( Boulton, DW; DeVane, CL; Markowitz, JS, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 14 (82.35) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Josefsson, M | 1 |
| Roman, M | 1 |
| Skogh, E | 1 |
| Dahl, ML | 1 |
| Kollroser, M | 1 |
| Schober, C | 1 |
| Putzhammer, A | 1 |
| Heindl, B | 1 |
| Müller, J | 1 |
| Broll, K | 1 |
| Pfeiff, L | 1 |
| Perfahl, M | 1 |
| Hess, L | 1 |
| Koch, H | 1 |
| Harris, A | 1 |
| Cox, S | 1 |
| Burns, D | 1 |
| Norey, C | 1 |
| Gervasini, G | 1 |
| Vizcaíno, S | 1 |
| Herráiz, AG | 1 |
| Benítez, J | 1 |
| Carrillo, JA | 1 |
| Chin, C | 1 |
| Zhang, ZP | 1 |
| Karnes, HT | 1 |
| Tu, J | 1 |
| Li, P | 1 |
| Yang, X | 1 |
| Pang, H | 1 |
| Lakshmanan, J | 1 |
| Oyachi, N | 1 |
| Ahanya, SA | 1 |
| Liu, G | 1 |
| Mazdak, M | 1 |
| Ross, MG | 1 |
| Chiu, JA | 1 |
| Franklin, RB | 1 |
| Rollema, H | 1 |
| Lu, Y | 1 |
| Schmidt, AW | 1 |
| Sprouse, JS | 1 |
| Zorn, SH | 1 |
| Raggi, MA | 1 |
| Casamenti, G | 1 |
| Mandrioli, R | 1 |
| Volterra, V | 1 |
| Bao, J | 1 |
| Potts, BD | 1 |
| Boulton, DW | 1 |
| Markowitz, JS | 1 |
| DeVane, CL | 1 |
| Weigmann, H | 1 |
| Härtter, S | 1 |
| Maehrlein, S | 1 |
| Kiefer, W | 1 |
| Krämer, G | 1 |
| Dannhardt, G | 1 |
| Hiemke, C | 1 |
| Berna, M | 1 |
| Ackermann, B | 1 |
| Ruterbories, K | 1 |
| Glass, S | 1 |
| Dusci, LJ | 1 |
| Peter Hackett, L | 1 |
| Fellows, LM | 1 |
| Ilett, KF | 1 |
| Harada, M | 1 |
| Koike, K | 1 |
| Takayanagi, I | 1 |
17 other studies available for pirenzepine and Sensitivity and Specificity
| Article | Year |
|---|---|
Liquid chromatography/tandem mass spectrometry method for determination of olanzapine and N-desmethylolanzapine in human serum and cerebrospinal fluid.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Drug Stability; | 2010 |
Direct-injection high performance liquid chromatography ion trap mass spectrometry for the quantitative determination of olanzapine, clozapine and N-desmethylclozapine in human plasma.
Topics: Antipsychotic Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Clozapine; Humans; Olan | 2002 |
[3-D ultrasound-assisted gait analysis of schizophrenic patients. Comparison between conventional neuroleptics and olanzapine].
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Equipment Design; Female; Gait Disorders, Neurol | 2003 |
Miniaturization of fluorescence polarization receptor-binding assays using CyDye-labeled ligands.
Topics: Animals; Atropine; Binding, Competitive; Carbocyanines; CHO Cells; Cricetinae; Fluorescence Polariza | 2003 |
Applicability of an assay for routine monitoring of highly variable concentrations of olanzapine based on HPLC with mass spectrometric detection.
Topics: Antipsychotic Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Drug Monitoring; Humans | 2003 |
A study of matrix effects on an LC/MS/MS assay for olanzapine and desmethyl olanzapine.
Topics: Anticoagulants; Benzodiazepines; Calibration; Chromatography, Liquid; Citrates; Edetic Acid; Heparin | 2004 |
HPLC determination of pirenzepine dihydrochloride in rabbit aqueous humor.
Topics: Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Pirenzepine; Rabbits; Reproducibility | 2005 |
Corticotropin-releasing factor inhibition of sheep fetal colonic contractility: mechanisms to prevent meconium passage in utero.
Topics: Animals; Bethanechol; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetus | 2007 |
Analysis and pharmacokinetics of olanzapine (LY170053) and two metabolites in rat plasma using reversed-phase HPLC with electrochemical detection.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Drug Stability | 1996 |
5-HT(1A) receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Clozapine; Cor | 2000 |
A sensitive high-performance liquid chromatographic method using electrochemical detection for the analysis of olanzapine and desmethylolanzapine in plasma of schizophrenic patients using a new solid-phase extraction procedure.
Topics: Antipsychotic Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Electrochemistry; Human | 2001 |
Quantitative determination of olanzapine in rat brain tissue by high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chromatography, High Pressure Liquid; Electro | 2001 |
A high-performance liquid chromatography assay with ultraviolet detection for olanzapine in human plasma and urine.
Topics: Antipsychotic Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Humans; Olanzapine; Pir | 2001 |
Simultaneous determination of olanzapine, clozapine and demethylated metabolites in serum by on-line column-switching high-performance liquid chromatography.
Topics: Antipsychotic Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Clozapine; Humans; Olan | 2001 |
Determination of olanzapine in human blood by liquid chromatography-tandem mass spectrometry.
Topics: Antipsychotic Agents; Benzodiazepines; Calibration; Chromatography, Liquid; Humans; Mass Spectrometr | 2002 |
Determination of olanzapine in plasma by high-performance liquid chromatography using ultraviolet absorbance detection.
Topics: Antipsychotic Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Humans; Olanzapine; Pir | 2002 |
Characterization of subtype of propylbenzilylcholine mustard (PrBCM)-sensitive and -resistant muscarinic cholinoceptors in guinea pig ileal muscle.
Topics: 4-Aminopyridine; Alkaloids; Animals; Drug Resistance; Furans; Guinea Pigs; Ileum; In Vitro Technique | 1992 |