1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine has been researched along with Sensitivity and Specificity in 8 studies
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine: A dopaminergic neurotoxic compound which produces irreversible clinical, chemical, and pathological alterations that mimic those found in Parkinson disease.
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine : A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Subramanian, T | 1 |
| Lieu, CA | 1 |
| Guttalu, K | 1 |
| Berg, D | 1 |
| Khaindrava, VG | 1 |
| Ershov, PV | 1 |
| Antsiperov, VE | 1 |
| Obukhov, IuV | 1 |
| Nanaev, AK | 1 |
| Ugriumov, MV | 1 |
| Tan, LC | 1 |
| Protell, PH | 1 |
| Langston, JW | 1 |
| Togasaki, DM | 1 |
| Hows, ME | 1 |
| Ashmeade, TE | 1 |
| Billinton, A | 1 |
| Perren, MJ | 1 |
| Austin, AA | 1 |
| Virley, DJ | 1 |
| Organ, AJ | 1 |
| Shah, AJ | 1 |
| Wei, Q | 1 |
| Yeung, M | 1 |
| Jurma, OP | 1 |
| Andersen, JK | 1 |
| Schmued, LC | 1 |
| Albertson, C | 1 |
| Slikker, W | 1 |
| Feng, MR | 1 |
| Atherton, J | 1 |
| Knoll, S | 1 |
| Strenkoski, CA | 1 |
| Wright, DS | 1 |
| Goodwin, BL | 1 |
| Kite, GC | 1 |
8 other studies available for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and Sensitivity and Specificity
| Article | Year |
|---|---|
Detection of MPTP-induced substantia nigra hyperechogenicity in Rhesus monkeys by transcranial ultrasound.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Female; Humans; Macac | 2010 |
[Optimization of counting process of dopaminergic neurons in substantia nigra of parkinsonian mice].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Count; Disease Models, Animal; Dopamine; | 2010 |
The hyperkinetic abnormal movements scale: a tool for measuring levodopa-induced abnormal movements in squirrel monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Female; Hyperkinesis; L | 2002 |
High-performance liquid chromatography/tandem mass spectrometry assay for the determination of 1-methyl-4-phenyl pyridinium (MPP+) in brain tissue homogenates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Ag | 2004 |
Genetic elevation of monoamine oxidase levels in dopaminergic PC12 cells results in increased free radical damage and sensitivity to MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Survival; Dopamine; Dopamine Agents; Fre | 1996 |
Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antihypertensive Agents; Axons; Dizocilpine M | 1997 |
Determination of two CI-1007 sulfate metabolites in monkey plasma and urine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antipsychotic Agents; Benzenesulfonates; Chro | 1997 |
Environmental MPTP as a factor in the aetiology of Parkinson's disease?
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Environmental Pollutants; Gas Chromatography-Mass Spec | 1998 |