Compounds > y 27632, dihydrochloride, (4(r)-trans)-isomer
Page last updated: 2024-08-02 11:37:26

y 27632, dihydrochloride, (4(r)-trans)-isomer

Description

Cross-References

ID SourceID
PubMed CID9901617
CHEMBL ID536267
CHEMBL ID1605605
SCHEMBL ID819702
SCHEMBL ID819701
MeSH IDM0327904

Synonyms (62)

Synonym
y-27632 (dihydrochloride)
HY-10583
y-27632 dihydrochloride, >=98% (hplc)
NCGC00092276-01
NCGC00093773-01
y-27632 dihydrochloride ,
(r)-(+)-trans-4-(1-aminoethyl)-n-(4-pyridyl)cyclohexanecarboxamide dihydrochloride
CHEMBL536267
trans-4-((r)-1-aminoethyl)-n-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride
y 27632 hcl
y 27632 hydrochloride
unii-q9828ii7f3
y 27632 dihydrochloride
q9828ii7f3 ,
CCG-100675
129830-38-2
CS-0878
(1r,4r)-4-((r)-1-aminoethyl)-n-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride
Y0018
SCHEMBL819702
SCHEMBL819701
NCGC00261018-01
tox21_500333
DTXSID3042635
S1049
y-27632 2hcl
trans-4-[(1r)-1-aminoethyl]-n-4-pyridinylcyclohexanecarboxamide dihydrochloride
y27632 2hcl
CHEMBL1605605
AC-35974
c14h21n3o.2hcl
HB2297
rock inhibitor y-27632
cyclohexanecarboxamide, 4-((1r)-1-aminoethyl)-n-4-pyridinyl-, dihydrochloride, trans-
(r)-(+)-trans-n-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecar boxamide, 2hcl
cyclohexanecarboxamide, 4-((1r)-1-aminoethyl)-n-4-pyridinyl-, hydrochloride (1:2), trans-
(+)-(r)-trans-4-(1-aminoethyl)-n-(4-pyridyl)cyclohexanecarboxamide dihydrochloride
AKOS024456492
SR-00000001060-1
sr-00000001060
J-005723
EX-A423
(r)-(+)-trans-n-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide dihydrochloride
(1r,4r)-4-[(1r)-1-aminoethyl]-n-(pyridin-4-yl)cyclohexane-1-carboxamide dihydrochloride
AS-74311
4-[(1r)-1-aminoethyl]-n-pyridin-4-ylcyclohexane-1-carboxamide dihydrochloride
SW219086-1
A888815
y-27632 - cas 146986-50-7
mfcd03490488
TB1254-GMP
EX-A3440
cyclohexanecarboxamide, 4-[(1r)-1-aminoethyl]-n-4-pyridinyl-, hydrochloride (1:2), trans-
Q27287129
4-[(1r)-1-aminoethyl]-n-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride
1983329-96-9
(r)-4-(1-aminoethyl)-n-(pyridin-4-yl)cyclohexane-1-carboxamide dihydrochloride
WFA98650
BY162499
CS-0615630
HY-10583G
y-27632 (dihydrochloride) (gmp)

Protein Targets (35)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency0.0447AID2517
thioredoxin reductaseRattus norvegicus (Norway rat)Potency0.5973AID588453
15-lipoxygenase, partialHomo sapiens (human)Potency25.1189AID887
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency25.0183AID1224819; AID1224820; AID1224821
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency79.4328AID504332
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency7.9433AID924
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency15.8489AID884; AID885
lamin isoform A-delta10Homo sapiens (human)Potency6.3096AID1487
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency15.8489AID885
Integrin beta-3Homo sapiens (human)Potency7.9433AID924
Integrin alpha-IIbHomo sapiens (human)Potency7.9433AID924
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency15.8489AID885
GABA theta subunitRattus norvegicus (Norway rat)Potency15.8489AID885
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency15.8489AID885

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
Rho-associated protein kinase 2Homo sapiens (human)IC500.0610AID483711
Rho-associated protein kinase 2Homo sapiens (human)Ki0.3000AID1675420
Cell division control protein 42 homologHomo sapiens (human)IC508.0000AID483716
Protein kinase C epsilon typeHomo sapiens (human)IC500.3350AID483714
Myotonin-protein kinaseHomo sapiens (human)IC508.0000AID483715
Rho-associated protein kinase 1Homo sapiens (human)IC500.0460AID483713
Rho-associated protein kinase 1Homo sapiens (human)Ki0.1400AID1675421; AID325793
Serine/threonine-protein kinase N2Homo sapiens (human)IC500.0700AID483717

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
Cytochrome P450 1A2Homo sapiens (human)INH10.0000AID483772
Cytochrome P450 3A4Homo sapiens (human)INH10.0000AID483774
Cytochrome P450 2D6Homo sapiens (human)INH3.2000AID483773

Bioassays (31)

Assay IDTitleYearJournalArticle
AID483769Half life in rat at 1 mg/kg, iv and 10 mg/kg, po2010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID1675420Inhibition of ROCK2 (unknown origin)2020Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
ISSN: 1464-3405		Identification of 5H-chromeno[3,4-c]pyridine and 6H-isochromeno[3,4-c]pyridine derivatives as potent and selective dual ROCK inhibitors.
AID483774Inhibition of CYP3A42010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483772Inhibition of CYP1A22010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483773Inhibition of CYP2D62010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483766Metabolic stability in human liver microsomes2010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483716Inhibition of CDc422010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483717Inhibition of Prkcl22010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483765Metabolic stability in rat liver microsomes2010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID1675421Inhibition of ROCK1 (unknown origin)2020Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
ISSN: 1464-3405		Identification of 5H-chromeno[3,4-c]pyridine and 6H-isochromeno[3,4-c]pyridine derivatives as potent and selective dual ROCK inhibitors.
AID483711Inhibition of ROCK22010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483771Oral bioavailability in rat at 10 mg/kg2010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483778Vasodilatory activity in Sprague-Dawley rat assessed as inhibition of aortic ring contraction2010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483713Inhibition of ROCK12010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID521220Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay2007Nature chemical biology, May, Volume: 3, Issue:5
ISSN: 1552-4450		Chemical genetics reveals a complex functional ground state of neural stem cells.
AID483776Cytotoxicity against human HeLa cells2010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483775Inhibition of human ERG2010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483767Solubility at pH 7.42010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483714Inhibition of Prkce2010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483715Inhibition of DMPK2010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483768Clearance in rat at 1 mg/kg, iv and 10 mg/kg, po2010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID483770AUC in rat at 1 mg/kg, iv and 10 mg/kg, po2010Bioorganic & medicinal chemistry letters, Jun-01, Volume: 20, Issue:11
ISSN: 1464-3405		Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.
AID1347059CD47-SIRPalpha protein protein interaction - Alpha assay qHTS validation2019PloS one, , Volume: 14, Issue:7
ISSN: 1932-6203		Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347410qHTS for inhibitors of adenylyl cyclases using a fission yeast platform: a pilot screen against the NCATS LOPAC library2019Cellular signalling, 08, Volume: 60ISSN: 1873-3913A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening.
AID1347151Optimization of GU AMC qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
ISSN: 1091-6490		Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347057CD47-SIRPalpha protein protein interaction - LANCE assay qHTS validation2019PloS one, , Volume: 14, Issue:7
ISSN: 1932-6203		Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347058CD47-SIRPalpha protein protein interaction - HTRF assay qHTS validation2019PloS one, , Volume: 14, Issue:7
ISSN: 1932-6203		Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
AID1347405qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS LOPAC collection2020ACS chemical biology, 07-17, Volume: 15, Issue:7
ISSN: 1554-8937		High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID250985Mean percent neurite outgrowth (cells with neurites longer than cell body/total cells) was determined in NG108-15 cells after 4 hr incubation at 35 uM2004Bioorganic & medicinal chemistry letters, Oct-04, Volume: 14, Issue:19
ISSN: 0960-894X		Synthesis and evaluation of 4-(1-aminoalkyl)-N-(4-pyridyl)cyclohexanecarboxamides as Rho kinase inhibitors and neurite outgrowth promoters.
AID325793Inhibition of p160ROCK2007Proceedings of the National Academy of Sciences of the United States of America, Dec-18, Volume: 104, Issue:51
ISSN: 1091-6490		A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
AID243250Percent control of rho kinase activity at 10 uM in the presence of 100 uM ATP2004Bioorganic & medicinal chemistry letters, Oct-04, Volume: 14, Issue:19
ISSN: 0960-894X		Synthesis and evaluation of 4-(1-aminoalkyl)-N-(4-pyridyl)cyclohexanecarboxamides as Rho kinase inhibitors and neurite outgrowth promoters.

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's3 (33.33)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
gamma-aminobutyric acid
1
amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid		human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule		2007200717.0low000100
acetamide
1
acetamides;
carboximidic acid;
monocarboxylic acid amide;
N-acylammonia		2007200717.0low000100
quinacrine
1
acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound		antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor		2007200717.0low000100
catechol
1
catecholsallelochemical;
genotoxin;
plant metabolite		2007200717.0low000100
taxifolin
1
3'-hydroxyflavanones;
4'-hydroxyflavanones;
dihydroflavonols;
pentahydroxyflavanone;
secondary alpha-hydroxy ketone		2007200717.0low000100
phosphonoacetic acid
1
monocarboxylic acid;
phosphonic acids		antiviral agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor		2007200717.0low000100
3,4-dihydroxyphenylacetic acid
1
catechols;
dihydroxyphenylacetic acid		human metabolite2007200717.0low000100
aminocaproic acid
1
amino acid zwitterion;
epsilon-amino acid;
omega-amino fatty acid		antifibrinolytic drug;
hematologic agent;
metabolite		2007200717.0low000100
diacetyl
1
alpha-diketoneEscherichia coli metabolite;
Saccharomyces cerevisiae metabolite		2007200717.0low000100
hydroquinone
1
benzenediol;
hydroquinones		antioxidant;
carcinogenic agent;
cofactor;
Escherichia coli metabolite;
human xenobiotic metabolite;
mouse metabolite;
skin lightening agent		2007200717.0low000100
melatonin
1
acetamides;
tryptamines		anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger		2007200717.0low000100
n-acetylserotonin
1
acetamides;
N-acylserotonin;
phenols		antioxidant;
human metabolite;
mouse metabolite;
tropomyosin-related kinase B receptor agonist		2007200717.0low000100
pyrazinamide
1
monocarboxylic acid amide;
N-acylammonia;
pyrazines		antitubercular agent;
prodrug		2007200717.0low000100
quinolinic acid
1
pyridinedicarboxylic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite;
NMDA receptor agonist		2007200717.0low000100
taurine
1
amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite		2007200717.0low000100
2-amino-5-phosphonovalerate
1
non-proteinogenic alpha-amino acidNMDA receptor antagonist2007200717.0low000100
alpha-methyl-4-carboxyphenylglycine
1
2007200717.0low000100
3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid
1
2007200717.0low000100
1-hydroxy-3-amino-2-pyrrolidone
1
2007200717.0low000100
ibotenic acid
1
non-proteinogenic alpha-amino acidneurotoxin2007200717.0low000100
n(8)-bromoacetyl-n(1)-3'-(4-indolyloxy)-2'-hydroxypropyl-1,8-diamino-4-menthane
1
2007200717.0medium000100
sk&f-38393
1
benzazepine;
catechols;
secondary amino compound		2007200717.0low000100
vanilmandelic acid
1
2-hydroxy monocarboxylic acid;
aromatic ether;
phenols		human metabolite2007200717.0low000100
1,10-diaminodecane
1
2007200717.0low000100
1,3-diethyl-8-phenylxanthine
1
2007200717.0low000100
1,3-dipropyl-8-cyclopentylxanthine
1
oxopurineadenosine A1 receptor antagonist;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor		2007200717.0low000100
1,3-dipropyl-8-(4-sulfophenyl)xanthine
1
2007200717.0low000100
1,5-dihydroxyisoquinoline
1
isoquinolinolEC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor2007200717.0low000100
pk 11195
1
aromatic amide;
isoquinolines;
monocarboxylic acid amide;
monochlorobenzenes		antineoplastic agent2007200717.0low000100
1-(2-trifluoromethylphenyl)imidazole
1
imidazoles2007200717.0low000100
1-aminobenzotriazole
1
2007200717.0low000100
1-methylimidazole
1
imidazoles2007200717.0low000100
edelfosine
1
glycerophosphocholine2007200717.0low000100
pd 173074
1
aromatic amine;
biaryl;
dimethoxybenzene;
pyridopyrimidine;
tertiary amino compound;
ureas		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
fibroblast growth factor receptor antagonist		2007200717.0low000100
1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one
1
oxadiazoloquinoxalineEC 4.6.1.2 (guanylate cyclase) inhibitor2007200717.0low000100
2,2'-dipyridyl
1
bipyridinechelator;
ferroptosis inhibitor		2007200717.0low000100
2-hydroxysaclofen
1
organochlorine compound2007200717.0low000100
3,4-dichloroisocoumarin
1
isocoumarins;
organochlorine compound		geroprotector;
serine protease inhibitor		2007200717.0low000100
phaclofen
1
organophosphate oxoanion;
zwitterion		2007200717.0low000100
3-aminobenzamide
1
benzamides;
substituted aniline		EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor2007200717.0low000100
3-bromo-7-nitroindazole
1
2007200717.0low000100
enprofylline
1
oxopurineanti-arrhythmia drug;
anti-asthmatic drug;
bronchodilator agent;
non-steroidal anti-inflammatory drug		2007200717.0low000100
3-nitropropionic acid
1
C-nitro compoundantimycobacterial drug;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor;
mycotoxin;
neurotoxin		2007200717.0low000100
4,5,6,7-tetrabromo-2-azabenzimidazole
1
2007200717.0low000100
4-amino-1,8-naphthalimide
1
benzoisoquinoline;
dicarboximide		2007200717.0low000100
4-aminopyridine
1
aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker		2007200717.0low000100
homovanillic acid
1
guaiacols;
monocarboxylic acid		human metabolite;
mouse metabolite		2007200717.0low000100
4-hydroxybenzoic acid hydrazide
1
carbohydrazide;
phenols		2007200717.0low000100
4-phenyl-3-furoxancarbonitrile
1
1,2,5-oxadiazole;
benzenes;
N-oxide;
nitrile		geroprotector;
nitric oxide donor;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent		2007200717.0low000100
5,5-dimethyl-1-pyrroline-1-oxide
1
1-pyrroline nitronesneuroprotective agent;
spin trapping reagent		2007200717.0low000100
phenytoin
1
imidazolidine-2,4-dioneanticonvulsant;
drug allergen;
sodium channel blocker;
teratogenic agent		2007200717.0low000100
5,7-dichlorokynurenic acid
1
quinolines2007200717.0low000100
5-(n,n-hexamethylene)amiloride
1
aromatic amine;
azepanes;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines		antineoplastic agent;
apoptosis inducer;
odorant receptor antagonist;
sodium channel blocker		2007200717.0low000100
ethylisopropylamiloride
1
aromatic amine;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines;
tertiary amino compound		anti-arrhythmia drug;
neuroprotective agent;
sodium channel blocker		2007200717.0low000100
5-fluoroindole-2-carboxylic acid
1
indolyl carboxylic acid2007200717.0low000100
hydroxyindoleacetic acid
1
indole-3-acetic acidsdrug metabolite;
human metabolite;
mouse metabolite		2007200717.0low000100
phenanthridone
1
lactam;
phenanthridines		EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
immunosuppressive agent;
mutagen		2007200717.0low000100
6-chloromelatonin
1
acetamides2007200717.0low000100
6-hydroxymelatonin
1
acetamides;
tryptamines		metabolite;
mouse metabolite		2007200717.0low000100
6-methoxytryptoline
1
2007200717.0low000100
6-nitroso-1,2-benzopyrone
1
2007200717.0low000100
7-chlorokynurenic acid
1
organochlorine compound;
quinolinemonocarboxylic acid		neuroprotective agent;
NMDA receptor antagonist		2007200717.0low000100
7-nitroindazole
1
2007200717.0low000100
8-(4-sulfophenyl)theophylline
1
2007200717.0low000100
8-cyclopentyl-1,3-dimethylxanthine
1
oxopurine2007200717.0low000100
8-phenyltheophylline
1
2007200717.0low000100
N-(2-aminoethyl)-5-chloro-1-naphthalenesulfonamide
1
naphthalenes;
sulfonic acid derivative		2007200717.0low000100
acetazolamide
1
monocarboxylic acid amide;
sulfonamide;
thiadiazoles		anticonvulsant;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor		2007200717.0low000100
acetohexamide
1
acetophenones;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue		2007200717.0low000100
ag 127
1
nitrophenol2007200717.0low000100
ag 1295
1
quinoxaline derivativegeroprotector2007200717.0low000100
rtki cpd
1
aromatic ether;
monochlorobenzenes;
quinazolines		antineoplastic agent;
antiviral agent;
epidermal growth factor receptor antagonist;
geroprotector		2007200717.0low000100
tyrphostin a23
2
catechols2007200717.0low000200
tyrphostin 25
1
benzenetriol2007200717.0low000100
tyrphostin a1
1
methoxybenzenesgeroprotector2007200717.0low000100
1-aminoindan-1,5-dicarboxylic acid
1
2007200717.0low000100
albuterol
1
phenols;
phenylethanolamines;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
environmental contaminant;
xenobiotic		2007200717.0low000100
alpha-methyltyrosine methyl ester
1
2007200717.0low000100
altretamine
1
triamino-1,3,5-triazine2007200717.0low000100
amfonelic acid
1
2007200717.0low000100
amifostine anhydrous
1
diamine;
organic thiophosphate		antioxidant;
prodrug;
radiation protective agent		2007200717.0low000100
theophylline
1
dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent		2007200717.0low000100
amoxapine
1
dibenzooxazepineadrenergic uptake inhibitor;
antidepressant;
dopaminergic antagonist;
geroprotector;
serotonin uptake inhibitor		2007200717.0low000100
aniracetam
1
N-acylpyrrolidine;
pyrrolidin-2-ones		2007200717.0low000100
2-amino-4-phosphonobutyric acid
1
2007200717.0low000100
aspirin
1
benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent		2007200717.0low000100
atenolol
1
ethanolamines;
monocarboxylic acid amide;
propanolamine		anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
sympatholytic agent;
xenobiotic		2007200717.0low000100
alpha-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionate
1
alpha-amino acid2007200717.0low000100
aurintricarboxylic acid
1
monohydroxybenzoic acid;
quinomethanes;
tricarboxylic acid		fluorochrome;
histological dye;
insulin-like growth factor receptor 1 antagonist		2007200717.0low000100
azathioprine
1
aryl sulfide;
C-nitro compound;
imidazoles;
thiopurine		antimetabolite;
antineoplastic agent;
carcinogenic agent;
DNA synthesis inhibitor;
hepatotoxic agent;
immunosuppressive agent;
prodrug		2007200717.0low000100
azelaic acid
1
alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		antibacterial agent;
antineoplastic agent;
dermatologic drug;
plant metabolite		2007200717.0low000100
baclofen
1
amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid;
monochlorobenzenes;
primary amino compound		central nervous system depressant;
GABA agonist;
muscle relaxant		2007200717.0low000100
bay-k-8644
1
(trifluoromethyl)benzenes;
C-nitro compound;
dihydropyridine;
methyl ester		2007200717.0low000100
benzamide
1
benzamides2007200717.0low000100
bepridil
1
pyrrolidines;
tertiary amine		anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent		2007200717.0low000100
bisindolylmaleimide i
1
2007200717.0low000100
bisindolylmaleimide iv
1
indoles;
maleimides		2007200717.0low000100
bml 190
1
N-acylindole2007200717.0low000100
bohemine
1
purinesEC 2.7.11.22 (cyclin-dependent kinase) inhibitor2007200717.0low000100
brimonidine
1
imidazoles;
quinoxaline derivative;
secondary amine		adrenergic agonist;
alpha-adrenergic agonist;
antihypertensive agent		2007200717.0low000100
bumetanide
1
amino acid;
benzoic acids;
sulfonamide		diuretic;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor		2007200717.0low000100
caffeine
1
purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic		2007200717.0low000100
carbamazepine
1
dibenzoazepine;
ureas		analgesic;
anticonvulsant;
antimanic drug;
drug allergen;
EC 3.5.1.98 (histone deacetylase) inhibitor;
environmental contaminant;
glutamate transporter activator;
mitogen;
non-narcotic analgesic;
sodium channel blocker;
xenobiotic		2007200717.0low000100
carbetapentane
1
benzenes2007200717.0low000100
carisoprodol
1
carbamate estermuscle relaxant2007200717.0low000100
carmustine
1
N-nitrosoureas;
organochlorine compound		alkylating agent;
antineoplastic agent		2007200717.0low000100
cgs 12066
1
N-arylpiperazine;
organofluorine compound;
pyrroloquinoxaline		serotonergic agonist2007200717.0low000100
cgs 15943
1
aromatic amine;
biaryl;
furans;
organochlorine compound;
primary amino compound;
quinazolines;
triazoloquinazoline		adenosine A1 receptor antagonist;
adenosine A2A receptor antagonist;
antineoplastic agent;
central nervous system stimulant		2007200717.0low000100
chelerythrine
1
benzophenanthridine alkaloid;
organic cation		antibacterial agent;
antineoplastic agent;
EC 2.7.11.13 (protein kinase C) inhibitor		2007200717.0low000100
chlorambucil
1
aromatic amine;
monocarboxylic acid;
nitrogen mustard;
organochlorine compound;
tertiary amino compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent		2007200717.0low000100
chlormezanone
1
1,3-thiazine;
lactam;
monochlorobenzenes;
sulfone		antipsychotic agent;
anxiolytic drug;
muscle relaxant		2007200717.0low000100
chlorothiazide
1
benzothiadiazineantihypertensive agent;
diuretic		2007200717.0low000100
chlorpropamide
1
monochlorobenzenes;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue		2007200717.0low000100
chlorzoxazone
1
1,3-benzoxazoles;
heteroaryl hydroxy compound;
organochlorine compound		muscle relaxant;
sedative		2007200717.0low000100
cilostamide
1
quinolines2007200717.0low000100
cilostazol
1
lactam;
tetrazoles		anticoagulant;
bronchodilator agent;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
fibrin modulating drug;
neuroprotective agent;
platelet aggregation inhibitor;
vasodilator agent		2007200717.0low000100
cimetidine
1
aliphatic sulfide;
guanidines;
imidazoles;
nitrile		adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor		2007200717.0low000100
cinoxacin
1
cinnolines;
oxacycle;
oxo carboxylic acid		antibacterial drug;
antiinfective agent		2007200717.0low000100
ciprofibrate
1
cyclopropanes;
monocarboxylic acid;
organochlorine compound		antilipemic drug2007200717.0low000100
clofibrate
1
aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist		2007200717.0low000100
clotrimazole
1
conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes		antiinfective agent;
environmental contaminant;
xenobiotic		2007200717.0low000100
cx546
1
2007200717.0low000100
cyclothiazide
1
benzothiadiazineantihypertensive agent;
diuretic		2007200717.0low000100
damnacanthal
1
aldehyde;
monohydroxyanthraquinone		2007200717.0low000100
dephostatin
1
2007200717.0low000100
nonivamide
1
capsaicinoid;
phenols		lachrymator2007200717.0low000100
r 59022
2
diarylmethane2007200717.0low000200
diazoxide
1
benzothiadiazine;
organochlorine compound;
sulfone		antihypertensive agent;
beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
diuretic;
K-ATP channel agonist;
sodium channel blocker;
sympathomimetic agent;
vasodilator agent		2007200717.0low000100
pentetic acid
1
pentacarboxylic acidcopper chelator2007200717.0low000100
diphenyleneiodonium
1
organic cation2007200717.0low000100
dipyridamole
1
piperidines;
pyrimidopyrimidine;
tertiary amino compound;
tetrol		adenosine phosphodiesterase inhibitor;
EC 3.5.4.4 (adenosine deaminase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent		2007200717.0low000100
disopyramide
1
monocarboxylic acid amide;
pyridines;
tertiary amino compound		anti-arrhythmia drug2007200717.0low000100
disulfiram
1
organic disulfide;
organosulfur acaricide		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
EC 3.1.1.1 (carboxylesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
ferroptosis inducer;
fungicide;
NF-kappaB inhibitor		2007200717.0low000100
2-amino-7-phosphonoheptanoic acid
1
2007200717.0low000100
thiorphan
1
N-acyl-amino acid2007200717.0low000100
n(6),n(6)-dimethyladenine
1
tertiary amine2007200717.0low000100
2,3-dimethoxy-1,4-naphthoquinone
1
1,4-naphthoquinones2007200717.0low000100
domperidone
1
benzimidazoles;
heteroarylpiperidine		antiemetic;
dopaminergic antagonist		2007200717.0low000100
droperidol
1
aromatic ketone;
benzimidazoles;
organofluorine compound		anaesthesia adjuvant;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic		2007200717.0low000100
ebselen
1
benzoselenazoleanti-inflammatory drug;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 3.5.4.1 (cytosine deaminase) inhibitor;
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor;
enzyme mimic;
ferroptosis inhibitor;
genotoxin;
hepatoprotective agent;
neuroprotective agent;
radical scavenger		2007200717.0low000100
ellipticine
2
indole alkaloid;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound;
polycyclic heteroarene		antineoplastic agent;
plant metabolite		2007200717.0low000200
emodin
1
trihydroxyanthraquinoneantineoplastic agent;
laxative;
plant metabolite;
tyrosine kinase inhibitor		2007200717.0low000100
ethosuximide
1
dicarboximide;
pyrrolidinone		anticonvulsant;
geroprotector;
T-type calcium channel blocker		2007200717.0low000100
etodolac
1
monocarboxylic acid;
organic heterotricyclic compound		antipyretic;
cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		2007200717.0low000100
felbamate
1
carbamate esteranticonvulsant;
neuroprotective agent		2007200717.0low000100
felodipine
1
dichlorobenzene;
dihydropyridine;
ethyl ester;
methyl ester		anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent		2007200717.0low000100
fenofibrate
1
aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic		2007200717.0low000100
flumazenil
1
ethyl ester;
imidazobenzodiazepine;
organofluorine compound		antidote to benzodiazepine poisoning;
GABA antagonist		2007200717.0low000100
fluorouracil
1
nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic		2007200717.0low000100
fluspirilene
1
diarylmethane2007200717.0low000100
flutamide
1
(trifluoromethyl)benzenes;
monocarboxylic acid amide		androgen antagonist;
antineoplastic agent		2007200717.0low000100
formoterol fumarate
1
formamides;
phenols;
phenylethanolamines;
secondary alcohol;
secondary amino compound		2007200717.0low000100
fpl 64176
1
carboxylic ester;
pyrroles		calcium channel agonist2007200717.0low000100
furafylline
1
oxopurine2007200717.0low000100
furosemide
1
chlorobenzoic acid;
furans;
sulfonamide		environmental contaminant;
loop diuretic;
xenobiotic		2007200717.0low000100
fusaric acid
1
aromatic carboxylic acid;
pyridines		2007200717.0low000100
gabapentin
1
gamma-amino acidanticonvulsant;
calcium channel blocker;
environmental contaminant;
xenobiotic		2007200717.0low000100
4-amino-5-hexynoic acid
1
2007200717.0low000100
glipizide
1
aromatic amide;
monocarboxylic acid amide;
N-sulfonylurea;
pyrazines		EC 2.7.1.33 (pantothenate kinase) inhibitor;
hypoglycemic agent;
insulin secretagogue		2007200717.0low000100
glyburide
1
monochlorobenzenes;
N-sulfonylurea		anti-arrhythmia drug;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor;
hypoglycemic agent		2007200717.0low000100
go 6976
1
indolocarbazole;
organic heterohexacyclic compound		EC 2.7.11.13 (protein kinase C) inhibitor2007200717.0low000100
1-(5-isoquinolinesulfonyl)piperazine
1
isoquinolines2007200717.0low000100
ha 1004
1
isoquinolines2007200717.0low000100
fasudil
3
isoquinolines;
N-sulfonyldiazepane		antihypertensive agent;
calcium channel blocker;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
geroprotector;
neuroprotective agent;
nootropic agent;
vasodilator agent		2007202011.7low000210
haloperidol
1
aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist		2007200717.0low000100
hemicholinium 3
1
morpholines2007200717.0low000100
4-fluorohexahydrosiladifenidol
1
2007200717.0low000100
hydrochlorothiazide
1
benzothiadiazine;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic		2007200717.0low000100
hydroxyurea
1
one-carbon compound;
ureas		antimetabolite;
antimitotic;
antineoplastic agent;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
genotoxin;
immunomodulator;
radical scavenger;
teratogenic agent		2007200717.0low000100
ibudilast
1
pyrazolopyridine2007200717.0low000100
ibuprofen
1
monocarboxylic acidantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic		2007200717.0low000100
ic 261
1
indoles2007200717.0medium000100
ifenprodil
1
piperidines2007200717.0low000100
indirubin-3'-monoxime
2
2007200717.0low000200
indomethacin
1
aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic		2007200717.0low000100
iodoacetamide
1
2007200717.0low000100
1-methyl-3-isobutylxanthine
1
3-isobutyl-1-methylxanthine2007200717.0low000100
4-piperidinecarboxylic acid
1
2007200717.0low000100
4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline
1
2007200717.0low000100
jl 18
1
2007200717.0low000100
nsc 664704
2
indolobenzazepine;
lactam;
organobromine compound		cardioprotective agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
geroprotector		2007200717.0low000200
ketoconazole
1
dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine		2007200717.0low000100
ketoprofen
1
benzophenones;
oxo monocarboxylic acid		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic		2007200717.0low000100
kynurenic acid
1
monohydroxyquinoline;
quinolinemonocarboxylic acid		G-protein-coupled receptor agonist;
human metabolite;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist;
Saccharomyces cerevisiae metabolite		2007200717.0low000100
2-amino-3-phosphonopropionic acid
1
alanine derivative;
non-proteinogenic alpha-amino acid;
phosphonic acids		human metabolite;
metabotropic glutamate receptor antagonist		2007200717.0low000100
lamotrigine
1
1,2,4-triazines;
dichlorobenzene;
primary arylamine		anticonvulsant;
antidepressant;
antimanic drug;
calcium channel blocker;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
excitatory amino acid antagonist;
geroprotector;
non-narcotic analgesic;
xenobiotic		2007200717.0low000100
lansoprazole
1
benzimidazoles;
pyridines;
sulfoxide		anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor		2007200717.0low000100
beta-lapachone
1
benzochromenone;
orthoquinones		anti-inflammatory agent;
antineoplastic agent;
plant metabolite		2007200717.0low000100
lavendustin a
1
aromatic amine2007200717.0low000100
2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acid
1
aromatic amine2007200717.0low000100
leflunomide
1
(trifluoromethyl)benzenes;
isoxazoles;
monocarboxylic acid amide		antineoplastic agent;
antiparasitic agent;
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
hepatotoxic agent;
immunosuppressive agent;
non-steroidal anti-inflammatory drug;
prodrug;
pyrimidine synthesis inhibitor;
tyrosine kinase inhibitor		2007200717.0low000100
linopirdine
1
indoles2007200717.0low000100
loratadine
1
benzocycloheptapyridine;
ethyl ester;
N-acylpiperidine;
organochlorine compound;
tertiary carboxamide		anti-allergic agent;
cholinergic antagonist;
geroprotector;
H1-receptor antagonist		2007200717.0low000100
loxoprofen
1
cyclopentanones;
monocarboxylic acid		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug		2007200717.0low000100
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
2
chromones;
morpholines;
organochlorine compound		autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector		2007200717.0low000200
meclofenamate sodium anhydrous
1
organic sodium salt2007200717.0low000100
methiothepin
1
aryl sulfide;
dibenzothiepine;
N-alkylpiperazine;
tertiary amino compound		antipsychotic agent;
dopaminergic antagonist;
geroprotector;
serotonergic antagonist		2007200717.0low000100
methoctramine
1
aromatic ether;
tetramine		muscarinic antagonist2007200717.0low000100
nocodazole
1
aromatic ketone;
benzimidazoles;
carbamate ester;
thiophenes		antimitotic;
antineoplastic agent;
microtubule-destabilising agent;
tubulin modulator		2007200717.0low000100
3-Hydroxy-alpha-methyl-DL-tyrosine
1
benzenes;
monocarboxylic acid		2007200717.0low000100
metolazone
1
organochlorine compound;
quinazolines;
sulfonamide		antihypertensive agent;
diuretic;
ion transport inhibitor		2007200717.0low000100
milrinone
1
bipyridines;
nitrile;
pyridone		cardiotonic drug;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent		2007200717.0low000100
minoxidil
1
dialkylarylamine;
tertiary amino compound		2007200717.0low000100
mitotane
1
diarylmethane2007200717.0low000100
mitoxantrone
1
dihydroxyanthraquinoneanalgesic;
antineoplastic agent		2007200717.0low000100
ml 7
1
N-sulfonyldiazepane;
organoiodine compound		EC 2.7.11.18 (myosin-light-chain kinase) inhibitor2007200717.0low000100
ml 9
1
naphthalenes;
sulfonic acid derivative		2007200717.0low000100
n-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide
1
naphthalenes;
organochlorine compound;
primary amino compound;
sulfonamide		2007200717.0low000100
n-bromoacetamide
1
2007200717.0low000100
ethylmaleimide
1
maleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor		2007200717.0low000100
fg 7142
1
beta-carbolines2007200717.0low000100
fenamic acid
1
aminobenzoic acid;
secondary amino compound		membrane transport modulator2007200717.0low000100
n 0840
1
2007200717.0low000100
nialamide
1
organonitrogen compound;
organooxygen compound		2007200717.0low000100
niclosamide
1
benzamides;
C-nitro compound;
monochlorobenzenes;
salicylanilides;
secondary carboxamide		anthelminthic drug;
anticoronaviral agent;
antiparasitic agent;
apoptosis inducer;
molluscicide;
piscicide;
STAT3 inhibitor		2007200717.0low000100
nifedipine
1
C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent		2007200717.0low000100
niflumic acid
1
aromatic carboxylic acid;
pyridines		2007200717.0low000100
nilutamide
1
(trifluoromethyl)benzenes;
C-nitro compound;
imidazolidinone		androgen antagonist;
antineoplastic agent		2007200717.0low000100
nimesulide
1
aromatic ether;
C-nitro compound;
sulfonamide		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug		2007200717.0low000100
nimodipine
1
2-methoxyethyl ester;
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
isopropyl ester		antihypertensive agent;
calcium channel blocker;
cardiovascular drug;
vasodilator agent		2007200717.0low000100
nipecotic acid
1
beta-amino acid;
piperidinemonocarboxylic acid		2007200717.0low000100
nitrendipine
1
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
ethyl ester;
methyl ester		antihypertensive agent;
calcium channel blocker;
geroprotector;
vasodilator agent		2007200717.0low000100
masoprocol
1
catechols;
lignan;
tetrol		antioxidant;
ferroptosis inhibitor;
geroprotector;
plant metabolite		2007200717.0low000100
5-nitro-2-(3-phenylpropylamino)benzoic acid
1
nitrobenzoic acid2007200717.0low000100
ns 2028
1
2007200717.0low000100
ns 1619
1
(trifluoromethyl)benzenes;
benzimidazoles;
phenols		potassium channel opener2007200717.0low000100
nu6102
1
2007200717.0low000100
o(6)-benzylguanine
1
2007200717.0low000100
ofloxacin
1
3-oxo monocarboxylic acid;
N-arylpiperazine;
N-methylpiperazine;
organofluorine compound;
oxazinoquinoline		2007200717.0low000100
olomoucine
2
2,6-diaminopurines;
ethanolamines		EC 2.7.11.22 (cyclin-dependent kinase) inhibitor2007200717.0low000200
oxaprozin
1
1,3-oxazoles;
monocarboxylic acid		analgesic;
non-steroidal anti-inflammatory drug		2007200717.0low000100
oxatomide
1
benzimidazoles;
diarylmethane;
N-alkylpiperazine		anti-allergic agent;
anti-inflammatory agent;
geroprotector;
H1-receptor antagonist;
serotonergic antagonist		2007200717.0low000100
oxiracetam
1
organonitrogen compound;
organooxygen compound		2007200717.0low000100
oxolinic acid
1
aromatic carboxylic acid;
organic heterotricyclic compound;
oxacycle;
quinolinemonocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antifungal agent;
antiinfective agent;
antimicrobial agent;
enzyme inhibitor		2007200717.0low000100
quinone
1
1,4-benzoquinonescofactor;
human xenobiotic metabolite;
mouse metabolite		2007200717.0low000100
fenclonine
1
phenylalanine derivative2007200717.0low000100
palmidrol
1
endocannabinoid;
N-(long-chain-acyl)ethanolamine;
N-(saturated fatty acyl)ethanolamine		anti-inflammatory drug;
anticonvulsant;
antihypertensive agent;
neuroprotective agent		2007200717.0low000100
1,7-dimethylxanthine
1
dimethylxanthinecentral nervous system stimulant;
human blood serum metabolite;
human xenobiotic metabolite;
mouse metabolite		2007200717.0low000100
pd 153035
1
aromatic amine;
aromatic ether;
bromobenzenes;
quinazolines;
secondary amino compound		EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist		2007200717.0low000100
pd 169316
1
imidazoles2007200717.0low000100
pd 98059
2
aromatic amine;
monomethoxyflavone		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector		2007200717.0low000200
pentamidine
1
aromatic ether;
carboxamidine;
diether		anti-inflammatory agent;
antifungal agent;
calmodulin antagonist;
chemokine receptor 5 antagonist;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
NMDA receptor antagonist;
S100 calcium-binding protein B inhibitor;
trypanocidal drug;
xenobiotic		2007200717.0low000100
pentoxifylline
1
oxopurine2007200717.0low000100
perphenazine
1
N-(2-hydroxyethyl)piperazine;
N-alkylpiperazine;
organochlorine compound;
phenothiazines		antiemetic;
dopaminergic antagonist;
phenothiazine antipsychotic drug		2007200717.0low000100
phenyl biguanide
1
guanidinescentral nervous system drug2007200717.0low000100
phenylbutazone
1
pyrazolidinesantirheumatic drug;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug		2007200717.0low000100
phloretin
1
dihydrochalconesantineoplastic agent;
plant metabolite		2007200717.0low000100
picotamide
1
benzamides2007200717.0low000100
pinacidil
1
pyridines2007200717.0low000100
pindolol
1
indoles;
secondary amine		antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist;
serotonergic antagonist;
vasodilator agent		2007200717.0low000100
piperidine-4-sulfonic acid
1
2007200717.0low000100
piracetam
1
organonitrogen compound;
organooxygen compound		2007200717.0low000100
pirenperone
1
aromatic ketone2007200717.0low000100
1-NA-PP1
1
pyrazolopyrimidinetyrosine kinase inhibitor2007200717.0low000100
ag 1879
1
aromatic amine;
monochlorobenzenes;
pyrazolopyrimidine		beta-adrenergic antagonist;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector		2007200717.0low000100
praziquantel
1
isoquinolines2007200717.0low000100
primidone
1
pyrimidoneanticonvulsant;
environmental contaminant;
xenobiotic		2007200717.0low000100
proglumide
1
benzamides;
dicarboxylic acid monoamide;
glutamine derivative;
racemate		anti-ulcer drug;
cholecystokinin antagonist;
cholinergic antagonist;
delta-opioid receptor agonist;
drug metabolite;
gastrointestinal drug;
opioid analgesic;
xenobiotic metabolite		2007200717.0low000100
propentofylline
1
oxopurine2007200717.0low000100
propofol
1
phenolsanticonvulsant;
antiemetic;
intravenous anaesthetic;
radical scavenger;
sedative		2007200717.0low000100
pf 5901
1
quinolines2007200717.0low000100
riluzole
1
benzothiazoles2007200717.0low000100
risperidone
1
1,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
psychotropic drug;
second generation antipsychotic;
serotonergic antagonist		2007200717.0low000100
ritanserin
1
organofluorine compound;
piperidines;
thiazolopyrimidine		antidepressant;
antipsychotic agent;
anxiolytic drug;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist		2007200717.0low000100
4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone
1
methoxybenzenes2007200717.0low000100
rolipram
1
pyrrolidin-2-onesantidepressant;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor		2007200717.0low000100
salmeterol xinafoate
1
ether;
phenols;
primary alcohol;
secondary alcohol;
secondary amino compound		2007200717.0low000100
sb 220025
1
aminopyrimidine;
imidazoles;
organofluorine compound;
piperidines		angiogenesis inhibitor;
anti-inflammatory agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor		2007200717.0low000100
sb 239063
1
imidazoles2007200717.0low000100
sb 202190
2
imidazoles;
organofluorine compound;
phenols;
pyridines		apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor		2007200717.0low000200
sobuzoxane
1
organic molecular entity2007200717.0low000100
spiroxatrine
1
imidazolidines2007200717.0low000100
sq 22536
1
nucleoside analogue;
oxolanes		EC 4.6.1.1 (adenylate cyclase) inhibitor2007200717.0low000100
sulfaphenazole
1
primary amino compound;
pyrazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 1.14.13.67 (quinine 3-monooxygenase) inhibitor;
P450 inhibitor		2007200717.0low000100
sulpiride
1
benzamides;
N-alkylpyrrolidine;
sulfonamide		antidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist		2007200717.0low000100
t0156
1
naphthyridine derivative2007200717.0low000100
1,4-bis(2-(3,5-dichloropyridyloxy))benzene
1
2007200717.0low000100
terfenadine
1
diarylmethane2007200717.0low000100
tetraisopropylpyrophosphamide
1
phosphoramide2007200717.0low000100
thalidomide
1
phthalimides;
piperidones		2007200717.0low000100
theobromine
1
dimethylxanthineadenosine receptor antagonist;
bronchodilator agent;
food component;
human blood serum metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent		2007200717.0low000100
8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate
1
trihydroxybenzoic acid2007200717.0low000100
tolazamide
1
N-sulfonylureahypoglycemic agent;
potassium channel blocker		2007200717.0low000100
tolbutamide
1
N-sulfonylureahuman metabolite;
hypoglycemic agent;
insulin secretagogue;
potassium channel blocker		2007200717.0low000100
(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid
1
2007200717.0low000100
ici 136,753
1
pyrazolopyridine2007200717.0low000100
triamterene
1
pteridinesdiuretic;
sodium channel blocker		2007200717.0low000100
trimethoprim
1
aminopyrimidine;
methoxybenzenes		antibacterial drug;
diuretic;
drug allergen;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
environmental contaminant;
xenobiotic		2007200717.0low000100
tropicamide
1
acetamides2007200717.0low000100
tyrphostin a9
1
alkylbenzenegeroprotector2007200717.0low000100
vigabatrin
1
gamma-amino acidanticonvulsant;
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor		2007200717.0low000100
whi p180
1
2007200717.0low000100
8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine
1
2007200717.0low000100
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole
1
aromatic primary alcohol;
furans;
indazoles		antineoplastic agent;
apoptosis inducer;
platelet aggregation inhibitor;
soluble guanylate cyclase activator;
vasodilator agent		2007200717.0low000100
zardaverine
1
organofluorine compound;
pyridazinone		anti-asthmatic drug;
bronchodilator agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
peripheral nervous system drug		2007200717.0low000100
zm 336372
1
benzamides2007200717.0low000100
cortisone acetate
1
corticosteroid hormone2007200717.0low000100
corticosterone
1
11beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite		2007200717.0low000100
reserpine
1
alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic		2007200717.0low000100
procaine hydrochloride
1
organic molecular entity2007200717.0low000100
isoproterenol hydrochloride
1
catechols2007200717.0low000100
histamine dihydrochloride
1
2007200717.0low000100
carbachol
1
ammonium salt;
carbamate ester		cardiotonic drug;
miotic;
muscarinic agonist;
nicotinic acetylcholine receptor agonist;
non-narcotic analgesic		2007200717.0low000100
spironolactone
1
3-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester		aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic		2007200717.0low000100
estrone
1
17-oxo steroid;
3-hydroxy steroid;
phenolic steroid;
phenols		antineoplastic agent;
bone density conservation agent;
estrogen;
human metabolite;
mouse metabolite		2007200717.0low000100
androsterone
1
17-oxo steroid;
3alpha-hydroxy steroid;
androstanoid;
C19-steroid		androgen;
anticonvulsant;
human blood serum metabolite;
human metabolite;
human urinary metabolite;
mouse metabolite;
pheromone		2007200717.0low000100
promazine hydrochloride
1
hydrochloride2007200717.0low000100
dichlororibofuranosylbenzimidazole
1
2007200717.0low000100
pilocarpine hydrochloride
1
hydrochloride2007200717.0low000100
dimethylphenylpiperazinium iodide
1
N-arylpiperazine;
organic iodide salt;
piperazinium salt;
quaternary ammonium salt		nicotinic acetylcholine receptor agonist2007200717.0low000100
pentylenetetrazole
1
organic heterobicyclic compound;
organonitrogen heterocyclic compound		2007200717.0low000100
racepinephrine hydrochloride
1
2007200717.0low000100
(4-(m-chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium chloride
1
2007200717.0low000100
hexamethonium bromide
1
2007200717.0low000100
cystamine dihydrochloride
1
2007200717.0medium000100
cantharidin
1
cyclic dicarboxylic anhydride;
monoterpenoid		EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
herbicide		2007200717.0low000100
tetraethylammonium chloride
1
organic chloride salt;
quaternary ammonium salt		potassium channel blocker2007200717.0low000100
aspartic acid
1
aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter		2007200717.0low000100
glutamine
1
amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite		2007200717.0low000100
vincristine
1
acetate ester;
formamides;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
tertiary alcohol;
tertiary amino compound;
vinca alkaloid		antineoplastic agent;
drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator		2007200717.0low000100
physostigmine
1
carbamate ester;
indole alkaloid		antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic		2007200717.0low000100
apomorphine
1
aporphine alkaloidalpha-adrenergic drug;
antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
emetic;
serotonergic drug		2007200717.0low000100
promethazine hydrochloride
1
hydrochlorideanti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
geroprotector;
H1-receptor antagonist;
local anaesthetic;
sedative		2007200717.0low000100
bromodeoxyuridine
1
pyrimidine 2'-deoxyribonucleosideantimetabolite;
antineoplastic agent		2007200717.0low000100
levodopa
1
amino acid zwitterion;
dopa;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		allelochemical;
antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
hapten;
human metabolite;
mouse metabolite;
neurotoxin;
plant growth retardant;
plant metabolite;
prodrug		2007200717.0low000100
methoxamine hydrochloride
1
dimethoxybenzene2007200717.0low000100
papaverine hydrochloride
1
2007200717.0low000100
bretylium tosylate
1
organosulfonate salt;
quaternary ammonium salt		adrenergic antagonist;
anti-arrhythmia drug;
antihypertensive agent		2007200717.0low000100
berlition
1
dithiolanes;
heterocyclic fatty acid;
lipoic acid;
thia fatty acid		cofactor;
nutraceutical;
prosthetic group		2007200717.0low000100
methacholine chloride
1
quaternary ammonium salt2007200717.0low000100
androstenedione
1
17-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite		2007200717.0low000100
colchicine
1
alkaloid;
colchicine		anti-inflammatory agent;
gout suppressant;
mutagen		2007200717.0low000100
yohimbine hydrochloride
1
2007200717.0low000100
gallamine triethiodide
1
2007200717.0low000100
cycloheximide
1
antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor		2007200717.0low000100
egtazic acid
1
diether;
tertiary amino compound;
tetracarboxylic acid		chelator2007200717.0low000100
cycloserine
1
4-amino-1,2-oxazolidin-3-one;
organonitrogen heterocyclic antibiotic;
organooxygen heterocyclic antibiotic;
zwitterion		antiinfective agent;
antimetabolite;
antitubercular agent;
metabolite;
NMDA receptor agonist		2007200717.0low000100
17-alpha-hydroxyprogesterone
1
17alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
tertiary alpha-hydroxy ketone		human metabolite;
metabolite;
mouse metabolite;
progestin		2007200717.0low000100
quinacrine monohydrochloride
1
2007200717.0medium000100
chlorpromazine hydrochloride
1
hydrochloride;
phenothiazines		anticoronaviral agent;
phenothiazine antipsychotic drug		2007200717.0low000100
cytarabine hydrochloride
1
2007200717.0low000100
tryptophan
1
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite		2007200717.0low000100
lidocaine hydrochloride
1
hydrochlorideanti-arrhythmia drug;
local anaesthetic		2007200717.0low000100
arginine
1
arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical		2007200717.0low000100
rotenone
1
organic heteropentacyclic compound;
rotenones		antineoplastic agent;
metabolite;
mitochondrial NADH:ubiquinone reductase inhibitor;
phytogenic insecticide;
piscicide;
toxin		2007200717.0low000100
synephrine
1
ethanolamines;
phenethylamine alkaloid;
phenols		alpha-adrenergic agonist;
plant metabolite		2007200717.0low000100
pyridostigmine bromide
1
pyridinium salt2007200717.0low000100
imipramine hydrochloride
1
hydrochlorideantidepressant2007200717.0low000100
neostigmine bromide
1
bromide salt2007200717.0low000100
edrophonium chloride
1
chloride salt;
quaternary ammonium salt		antidote;
diagnostic agent;
EC 3.1.1.8 (cholinesterase) inhibitor		2007200717.0low000100
suramin sodium
1
organic sodium saltangiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug		2007200717.0low000100
pyrazolanthrone
2
anthrapyrazole;
aromatic ketone;
cyclic ketone		antineoplastic agent;
c-Jun N-terminal kinase inhibitor;
geroprotector		2007200717.0low000200
1,4-naphthoquinone
1
1,4-naphthoquinones2007200717.0low000100
methapyrilene hydrochloride
1
hydrochlorideanti-allergic agent;
carcinogenic agent;
H1-receptor antagonist;
sedative		2007200717.0low000100
tetrracaine hydrochloride
1
benzoate ester2007200717.0low000100
chelidamic acid
1
2007200717.0low000100
2-chloroadenosine
1
purine nucleoside2007200717.0low000100
diphenhydramine hydrochloride
1
hydrochloride;
organoammonium salt		anti-allergic agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
sedative		2007200717.0low000100
cysteamine hydrochloride
1
2007200717.0low000100
propantheline bromide
1
xanthenes2007200717.0low000100
hydralazine hydrochloride
1
hydrochlorideantihypertensive agent;
vasodilator agent		2007200717.0low000100
ethamivan
1
methoxybenzenes;
phenols		2007200717.0low000100
pargyline hydrochloride
1
2007200717.0low000100
aminophylline
1
mixturebronchodilator agent;
cardiotonic drug		2007200717.0low000100
azacitidine
1
N-glycosyl-1,3,5-triazine;
nucleoside analogue		antineoplastic agent2007200717.0low000100
orphenadrine hydrochloride
1
hydrochlorideantiparkinson drug;
H1-receptor antagonist;
muscarinic antagonist;
muscle relaxant;
NMDA receptor antagonist;
parasympatholytic		2007200717.0low000100
betamethasone
1
11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic agent;
anti-inflammatory drug;
immunosuppressive agent		2007200717.0low000100
benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(n,n-dimethyl-n-2-propenyl-), dibromide
1
2007200717.0low000100
cyproterone acetate
1
20-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
chlorinated steroid;
steroid ester		androgen antagonist;
geroprotector;
progestin		2007200717.0low000100
bicuculline
1
benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines		agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin		2007200717.0low000100
kainic acid
1
dicarboxylic acid;
L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid		antinematodal drug;
excitatory amino acid agonist		2007200717.0low000100
podophyllotoxin
1
furonaphthodioxole;
lignan;
organic heterotetracyclic compound		antimitotic;
antineoplastic agent;
keratolytic drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator		2007200717.0low000100
tetrahydrozoline hydrochloride
1
hydrochloridenasal decongestant;
sympathomimetic agent;
vasoconstrictor agent		2007200717.0low000100
dequalinium chloride
1
organic chloride saltantifungal agent;
antineoplastic agent;
antiseptic drug;
mitochondrial NADH:ubiquinone reductase inhibitor		2007200717.0low000100
decamethonium dibromide
1
2007200717.0low000100
amitriptyline hydrochloride
1
organic tricyclic compound2007200717.0low000100
naphazoline hydrochloride
1
organic molecular entity2007200717.0low000100
doxylamine succinate
1
organic molecular entity2007200717.0low000100
carbamylhydrazine monohydrochloride
1
organic molecular entity2007200717.0medium000100
formestane
1
17-oxo steroid;
3-oxo-Delta(4) steroid;
enol;
hydroxy steroid		antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor		2007200717.0low000100
debrisoquin sulfate
1
organic sulfate salt2007200717.0low000100
betaine hydrochloride
1
2007200717.0low000100
bethanechol chloride
1
carbamate ester;
chloride salt;
quaternary ammonium salt		muscarinic agonist2007200717.0low000100
acetylcysteine
1
acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary		2007200717.0low000100
Mecamylamine hydrochloride
1
monoterpenoid2007200717.0medium000100
vinblastine
1
2007200717.0low000100
cyproheptadine hydrochloride (anhydrous)
1
hydrochloride2007200717.0low000100
5 alpha-androstane-3 alpha,17 beta-diol
1
androstane-3alpha,17beta-diolDaphnia magna metabolite;
human metabolite		2007200717.0low000100
pimozide
1
benzimidazoles;
heteroarylpiperidine;
organofluorine compound		antidyskinesia agent;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist		2007200717.0low000100
azetidyl-2-carboxylic acid
1
azetidine-2-carboxylic acid2007200717.0low000100
muscarine
1
2007200717.0medium000100
antazoline hydrochloride
1
2007200717.0low000100
doxifluridine
1
organofluorine compound;
pyrimidine 5'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
prodrug		2007200717.0low000100
meclofenoxate hydrochloride
1
2007200717.0low000100
clonidine hydrochloride
1
dichlorobenzene2007200717.0low000100
beclomethasone
1
11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
corticosteroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic drug;
anti-inflammatory drug		2007200717.0low000100
buthionine sulfoximine
1
diastereoisomeric mixture;
homocysteines;
non-proteinogenic alpha-amino acid;
sulfoximide		EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer		2007200717.0low000100
mexiletine hydrochloride
1
hydrochlorideanti-arrhythmia drug2007200717.0low000100
cyclophosphamide
1
hydratealkylating agent;
antineoplastic agent;
carcinogenic agent;
immunosuppressive agent		2007200717.0low000100
suxamethonium chloride
1
chloride saltmuscle relaxant2007200717.0low000100
cyclobenzaprine hydrochloride
1
hydrochlorideantidepressant;
muscle relaxant		2007200717.0low000100
n-methylaspartate
1
amino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound		neurotransmitter agent2007200717.0low000100
3-deazaadenosine
1
2007200717.0low000100
metoclopramide hydrochloride
1
2007200717.0low000100
isoetharine mesylate
1
2007200717.0low000100
zalcitabine
1
pyrimidine 2',3'-dideoxyribonucleosideantimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor		2007200717.0low000100
propionylpromazine hydrochloride
1
2007200717.0low000100
camptothecin
1
delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite		2007200717.0low000100
nsc-145,668
1
hydrochlorideantimetabolite;
antineoplastic agent		2007200717.0medium000100
clodronic acid
1
1,1-bis(phosphonic acid);
one-carbon compound;
organochlorine compound		antineoplastic agent;
bone density conservation agent		2007200717.0low000100
benserazide hydrochloride
1
hydrochlorideantiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor		2007200717.0low000100
pancuronium bromide
1
bromide saltcholinergic antagonist;
muscle relaxant;
nicotinic antagonist		2007200717.0medium000100
tetradecanoylphorbol acetate
1
acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator		2007200717.0low000100
danazol
1
17beta-hydroxy steroid;
terminal acetylenic compound		anti-estrogen;
estrogen antagonist;
geroprotector		2007200717.0low000100
metergoline
1
carbamate ester;
ergoline alkaloid		dopamine agonist;
geroprotector;
serotonergic antagonist		2007200717.0low000100
lisuride
1
monocarboxylic acid amideantidyskinesia agent;
antiparkinson drug;
dopamine agonist;
serotonergic agonist		2007200717.0low000100
disopyramide phosphate
1
organoammonium phosphate2007200717.0low000100
bromocriptine
1
indole alkaloidantidyskinesia agent;
antiparkinson drug;
dopamine agonist;
hormone antagonist		2007200717.0low000100
ergocristine
1
ergot alkaloid2007200717.0low000100
triamcinolone
1
11beta-hydroxy steroid;
16alpha-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-allergic agent;
anti-inflammatory drug		2007200717.0low000100
zidovudine
1
azide;
pyrimidine 2',3'-dideoxyribonucleoside		antimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor		2007200717.0low000100
paclitaxel
1
taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent		2007200717.0low000100
buspirone hydrochloride
1
hydrochlorideanxiolytic drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
sedative;
serotonergic agonist		2007200717.0low000100
etoposide
1
beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor		2007200717.0low000100
propafenone hydrochloride
1
hydrochlorideanti-arrhythmia drug2007200717.0low000100
etazolate hydrochloride
1
2007200717.0low000100
butaclamol
1
amino alcohol;
organic heteropentacyclic compound;
tertiary alcohol;
tertiary amino compound		dopaminergic antagonist2007200717.0low000100
ribavirin
1
1-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide		anticoronaviral agent;
antiinfective agent;
antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor		2007200717.0low000100
carbidopa
1
catechols;
hydrate;
hydrazines;
monocarboxylic acid		antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor		2007200717.0low000100
cephradine
1
beta-lactam antibiotic allergen;
cephalosporin		antibacterial drug2007200717.0low000100
methyldopa
1
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		alpha-adrenergic agonist;
antihypertensive agent;
hapten;
peripheral nervous system drug;
sympatholytic agent		2007200717.0low000100
lonidamine
1
dichlorobenzene;
indazoles;
monocarboxylic acid		antineoplastic agent;
antispermatogenic agent;
EC 2.7.1.1 (hexokinase) inhibitor;
geroprotector		2007200717.0low000100
dexibuprofen
1
ibuprofennon-narcotic analgesic;
non-steroidal anti-inflammatory drug		2007200717.0low000100
quisqualic acid
1
non-proteinogenic alpha-amino acid2007200717.0low000100
pirfenidone
1
pyridoneantipyretic;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug		2007200717.0low000100
flecainide acetate
1
acetate saltanti-arrhythmia drug2007200717.0low000100
nicardipine hydrochloride
1
dihydropyridinegeroprotector2007200717.0low000100
idarubicin
1
anthracycline antibiotic;
deoxy hexoside;
monosaccharide derivative		2007200717.0low000100
captopril
1
alkanethiol;
L-proline derivative;
N-acylpyrrolidine;
pyrrolidinemonocarboxylic acid		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor		2007200717.0low000100
staurosporine
1
indolocarbazole alkaloid;
organic heterooctacyclic compound		apoptosis inducer;
bacterial metabolite;
EC 2.7.11.13 (protein kinase C) inhibitor;
geroprotector		2007200717.0low000100
terazosin hydrochloride anhydrous
1
2007200717.0low000100
pergolide mesylate
1
methanesulfonate saltantiparkinson drug;
dopamine agonist;
geroprotector		2007200717.0low000100
ranitidine hydrochloride
1
2007200717.0medium000100
colforsin
1
acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol		adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist		2007200717.0low000100
cefaclor anhydrous
1
cephalosporinantibacterial drug;
drug allergen		2007200717.0low000100
alo 2145
1
hydrochloridealpha-adrenergic agonist;
antiglaucoma drug		2007200717.0medium000100
enoximone
1
aromatic ketone2007200717.0low000100
atomoxetine
1
aromatic ether;
secondary amino compound;
toluenes		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
xenobiotic		2007200717.0low000100
raloxifene hydrochloride
1
hydrochloridebone density conservation agent;
estrogen antagonist;
estrogen receptor modulator		2007200717.0low000100
mifepristone
1
3-oxo-Delta(4) steroid;
acetylenic compound;
tertiary amino compound		abortifacient;
contraceptive drug;
hormone antagonist;
synthetic oral contraceptive		2007200717.0low000100
quinpirole hydrochloride
1
2007200717.0low000100
imazodan
1
2007200717.0low000100
mibefradil dihydrochloride
1
2007200717.0low000100
aptiganel hydrochloride
1
2007200717.0low000100
adenosine
1
adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent		2007200717.0low000100
phenelzine sulfate
1
organic molecular entity2007200717.0low000100
fluoxetine hydrochloride
1
hydrochloride;
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine		2007200717.0low000100
propranolol hydrochloride
1
hydrochloride2007200717.0low000100
bupropion hydrochloride
1
aromatic ketone2007200717.0low000100
diltiazem hydrochloride
1
hydrochlorideantihypertensive agent;
calcium channel blocker;
vasodilator agent		2007200717.0low000100
trazodone hydrochloride
1
hydrochlorideadrenergic antagonist;
antidepressant;
H1-receptor antagonist;
sedative;
serotonin uptake inhibitor		2007200717.0low000100
verapamil hydrochloride
1
2007200717.0low000100
doxazosin mesylate
1
methanesulfonate saltgeroprotector2007200717.0low000100
terfenadine
1
diarylmethane2007200717.0low000100
amantadine hydrochloride
1
hydrochlorideantiviral agent;
dopamine agonist;
NMDA receptor antagonist		2007200717.0low000100
mevastatin
1
2-pyranones;
carboxylic ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		antifungal agent;
apoptosis inducer;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
fungal metabolite;
Penicillium metabolite		2007200717.0low000100
chloroquine diphosphate
1
2007200717.0low000100
arctigenin
1
lignan2007200717.0low000100
dobutamine hydrochloride
1
hydrochloridebeta-adrenergic agonist;
cardiotonic drug;
sympathomimetic agent		2007200717.0low000100
desipramine hydrochloride
1
hydrochloridedrug allergen2007200717.0low000100
dopamine hydrochloride
1
catecholamine2007200717.0low000100
proadifen hydrochloride
1
2007200717.0low000100
4-nitrobenzylthioinosine
1
purine nucleoside2007200717.0low000100
metrifudil
1
2007200717.0low000100
rutecarpine
1
beta-carbolines2007200717.0low000100
trihexyphenidyl hydrochloride
1
aralkylamine2007200717.0low000100
thioridazine hydrochloride
1
hydrochloridefirst generation antipsychotic;
geroprotector		2007200717.0low000100
procainamide hydrochloride
1
hydrochlorideanti-arrhythmia drug2007200717.0low000100
siquil
1
hydrochlorideanticoronaviral agent2007200717.0low000100
sotalol hydrochloride
1
hydrochlorideanti-arrhythmia drug;
beta-adrenergic antagonist		2007200717.0low000100
oxymetazoline hydrochloride
1
hydrochloridealpha-adrenergic agonist;
nasal decongestant;
sympathomimetic agent;
vasoconstrictor agent		2007200717.0low000100
alprenolol hydrochloride
1
hydrochloride2007200717.0low000100
2-methoxyestradiol
1
17beta-hydroxy steroid;
3-hydroxy steroid		angiogenesis modulating agent;
antimitotic;
antineoplastic agent;
human metabolite;
metabolite;
mouse metabolite		2007200717.0low000100
fluphenazine hydrochloride
1
phenothiazinesanticoronaviral agent2007200717.0low000100
tryptamine monohydrochloride
1
2007200717.0medium000100
clomipramine hydrochloride
1
hydrochlorideanticoronaviral agent;
antidepressant;
serotonergic antagonist;
serotonergic drug		2007200717.0low000100
amiloride hydrochloride
1
hydratediuretic;
sodium channel blocker		2007200717.0low000100
prazosin hydrochloride
1
hydrochloride2007200717.0low000100
mianserin hydrochloride
1
hydrochloridegeroprotector2007200717.0low000100
lomefloxacin hydrochloride
1
hydrochlorideantimicrobial agent;
antitubercular agent;
photosensitizing agent		2007200717.0low000100
fenspiride hydrochloride
1
2007200717.0low000100
nilverm
1
organic molecular entity2007200717.0low000100
sanguinarine chloride
1
2007200717.0low000100
ropinirole hydrochloride
1
indoles2007200717.0medium000100
plasmenylserine
1
O-phosphoserineEC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor;
EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor;
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite		2007200717.0low000100
5-aminovaleric acid hydrochloride
1
2007200717.0low000100
n-acetyltryptamine
1
acetamides;
indoles		2007200717.0low000100
D-serine
1
D-alpha-amino acid;
serine zwitterion;
serine		Escherichia coli metabolite;
human metabolite;
NMDA receptor agonist		2007200717.0low000100
dihydroergotamine mesylate
1
methanesulfonate saltnon-narcotic analgesic;
serotonergic agonist;
vasoconstrictor agent		2007200717.0low000100
ranolazine hydrochloride
1
2007200717.0medium000100
loxapine succinate
1
succinate saltgeroprotector2007200717.0low000100
guanfacine hydrochloride
1
acetamidesgeroprotector2007200717.0low000100
pirenzepine dihydrochloride
1
hydrochloride2007200717.0medium000100
labetalol hydrochloride
1
salicylamides2007200717.0low000100
acecainide hydrochloride
1
2007200717.0low000100
loperamide hydrochloride
1
hydrochlorideanticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist		2007200717.0low000100
maprotiline hydrochloride
1
anthracenes2007200717.0low000100
protoporphyrin ix, disodium salt
1
2007200717.0low000100
siguazodan
1
pyridazinone2007200717.0low000100
3-octadecanamido-2-ethoxypropylphosphocholine
1
2007200717.0low000100
chelerythrine chloride
2
2007200717.0medium000200
tosyllysine chloromethyl ketone
1
2007200717.0low000100
fascaplysine
1
2007200717.0low000100
5-(n-methyl-n-isobutyl)amiloride
1
2007200717.0low000100
1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride
1
hydrochlorideEC 2.7.11.13 (protein kinase C) inhibitor2007200717.0medium000100
amperozide hydrochloride
1
hydrochlorideanxiolytic drug;
dopamine uptake inhibitor;
geroprotector;
second generation antipsychotic;
serotonergic antagonist		2007200717.0low000100
pyrrolidine dithiocarbamic acid
1
2007200717.0medium000100
agroclavine
1
ergot alkaloid2007200717.0low000100
s-methylisothiourea sulfate
1
2007200717.0medium000100
p-Aminobenzamidine dihydrochloride
1
organic molecular entity2007200717.0medium000100
benzamidine hydrochloride
1
2007200717.0medium000100
ketorolac tromethamine
1
organoammonium saltanalgesic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor		2007200717.0low000100
methionine sulfoximine
1
L-alpha-amino acid zwitterion;
L-methionine derivative;
methionine sulfoximine;
non-proteinogenic L-alpha-amino acid		EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor;
geroprotector		2007200717.0low000100
tretazicar
1
2007200717.0low000100
carbetapentane citrate
1
carbonyl compound2007200717.0low000100
phentolamine mesylate
1
2007200717.0low000100
mephentermine
1
2-aminooctadecane-1,3-diolEC 2.7.11.13 (protein kinase C) inhibitor;
human metabolite;
mouse metabolite		2007200717.0low000100
oxybutynin hydrochloride
1
hydrochloride2007200717.0low000100
nimustine
1
hydrochlorideantineoplastic agent2007200717.0medium000100
cordium
1
hydrate;
hydrochloride		2007200717.0medium000100
L-2-aminoadipic acid
1
2-aminoadipic acidEscherichia coli metabolite;
human metabolite		2007200717.0low000100
prilocaine hydrochloride
1
hydrochloridelocal anaesthetic2007200717.0low000100
mor-14
1
hydroxypiperidine;
piperidine alkaloid;
tertiary amino compound		anti-HIV agent;
cardioprotective agent;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
plant metabolite		2007200717.0low000100
brexanolone
1
3-hydroxy-5alpha-pregnan-20-oneantidepressant;
GABA modulator;
human metabolite;
intravenous anaesthetic;
sedative		2007200717.0low000100
phenylisopropyladenosine
1
aromatic amine;
benzenes;
hydrocarbyladenosine;
purine nucleoside;
secondary amino compound		adenosine A1 receptor agonist;
neuroprotective agent		2007200717.0low000100
hexamethonium chloride
1
2007200717.0low000100
6-(4-nitrobenzylthio)guanosine
1
2007200717.0low000100
5-iodotubercidin
1
organoiodine compound2007200717.0low000100
3-aminopropylphosphonic acid
1
phosphonic acids;
primary amino compound;
zwitterion		GABAB receptor agonist2007200717.0low000100
5'-n-methylcarboxamideadenosine
1
2007200717.0low000100
3,7-dimethyl-1-propargylxanthine
1
2007200717.0low000100
zpck
1
2007200717.0low000100
n(6)-phenyladenosine
1
purine nucleoside2007200717.0low000100
tetrahydrodeoxycorticosterone
1
21-hydroxy steroid2007200717.0low000100
n-methyladenosine
1
methyladenosine2007200717.0low000100
mizoribine
1
imidazolesanticoronaviral agent2007200717.0low000100
1-amino-1,3-dicarboxycyclopentane
1
2007200717.0low000100
u 73122
1
aromatic ether;
aza-steroid;
maleimides		EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor2007200717.0low000100
alphaxalone
1
corticosteroid hormone2007200717.0low000100
s-nitrosoglutathione
1
glutathione derivative;
nitrosothio compound		bronchodilator agent;
nitric oxide donor;
platelet aggregation inhibitor;
signalling molecule		2007200717.0low000100
cp-55,940
1
2007200717.0low000100
vanoxerine
1
hydrochloridedopamine uptake inhibitor2007200717.0low000100
methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate
1
beta-carbolines2007200717.0low000100
u 69593
1
monocarboxylic acid amide;
N-alkylpyrrolidine;
organic heterobicyclic compound;
oxaspiro compound		anti-inflammatory agent;
diuretic;
kappa-opioid receptor agonist		2007200717.0low000100
cv 3988
1
2007200717.0low000100
beta-carboline-3-carboxylic acid methyl ester
1
beta-carbolines2007200717.0low000100
methoctramine
1
hydrochloridemuscarinic antagonist2007200717.0low000100
hypotaurine
1
aminosulfinic acid;
zwitterion		human metabolite;
metabolite;
mouse metabolite		2007200717.0low000100
dihydrokainate
1
dicarboxylic acid2007200717.0low000100
gabazine
1
2007200717.0medium000100
cl 218872
1
pyridazines;
ring assembly		2007200717.0low000100
betaxolol hydrochloride
1
hydrochlorideantihypertensive agent;
beta-adrenergic antagonist		2007200717.0low000100
catechin
1
hydrategeroprotector2007200717.0medium000100
1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine
1
hydrobromideserotonergic antagonist2007200717.0medium000100
s-methylthiocitrulline
1
imidothiocarbamic ester;
L-arginine derivative;
L-ornithine derivative;
non-proteinogenic L-alpha-amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
neuroprotective agent		2007200717.0low000100
dihydrocapsaicin
1
capsaicinoid2007200717.0low000100
ml 9
1
2007200717.0low000100
parthenolide
1
germacranolide2007200717.0low000100
3',4'-dichlorobenzamil
1
guanidines;
pyrazines		2007200717.0low000100
1-(carboxymethylthio)tetradecane
1
straight-chain fatty acid2007200717.0low000100
2-iodomelatonin
1
acetamides2007200717.0low000100
arcaine, sulfate
1
2007200717.0low000100
gr 113808
1
indolyl carboxylate ester;
piperidines;
sulfonamide		serotonergic antagonist2007200717.0low000100
gallopamil hydrochloride
1
2007200717.0low000100
gamma-glutamylaminomethylsulfonic acid
1
2007200717.0low000100
buthionine sulfoximine
1
2-amino-4-(S-butylsulfonimidoyl)butanoic acidEC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer		2007200717.0low000100
sb 204070a
1
2007200717.0low000100
1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine
1
(trifluoromethyl)benzenes;
N-alkylpiperazine;
N-arylpiperazine;
primary arylamine;
substituted aniline		geroprotector;
serotonergic agonist		2007200717.0low000100
l 655240
1
methylindole2007200717.0low000100
san 58035
1
2007200717.0low000100
imatinib mesylate
1
methanesulfonate saltanticoronaviral agent;
antineoplastic agent;
apoptosis inducer;
tyrosine kinase inhibitor		2007200717.0low000100
gefitinib
1
aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
quinazolines;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
epidermal growth factor receptor antagonist		2007200717.0low000100
nnc 711
1
2007200717.0low000100
4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide
1
diarylmethane2007200717.0low000100
e 64
1
dicarboxylic acid monoamide;
epoxy monocarboxylic acid;
guanidines;
L-leucine derivative;
zwitterion		antimalarial;
antiparasitic agent;
protease inhibitor		2007200717.0low000100
azetidine-2,4-dicarboxylic acid
1
2007200717.0low000100
pre 084
1
morpholines2007200717.0low000100
methotrexate
1
dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent		2007200717.0low000100
1-(2-allylphenoxy)-3-((8-bromoacetylamino-4-menthane-1-yl)amino)-1-propanol
1
2007200717.0low000100
sr 2640
1
quinolines2007200717.0low000100
ici 204448
1
2007200717.0medium000100
4-amino-1-(6-chloro-2-pyridyl)piperidine hydrochloride
1
2007200717.0low000100
n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide
1
phenylindole2007200717.0low000100
3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan
1
2007200717.0low000100
8-cyclopentyl-3-(3-((4-(fluorosulfonyl)benzoyl)oxy)propyl)-1-propylxanthine
1
2007200717.0low000100
l 741626
1
piperidines2007200717.0low000100
nisoxetine hydrochloride
1
2007200717.0low000100
ng-nitroarginine methyl ester
1
hydrochlorideEC 1.14.13.39 (nitric oxide synthase) inhibitor2007200717.0low000100
tilarginine acetate
1
2007200717.0low000100
alpha-guanidinoglutaric acid
1
L-glutamic acid derivative2007200717.0low000100
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (trans)-(+-)-isomer
1
2007200717.0low000100
imidazole-4-acetic acid hydrochloride
1
2007200717.0medium000100
nsc-141549
1
2007200717.0low000100
vatalanib
1
monochlorobenzenes;
phthalazines;
pyridines;
secondary amino compound		angiogenesis inhibitor;
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
vascular endothelial growth factor receptor antagonist		2007200717.0low000100
2-chloro-2-deoxyglucose
1
2007200717.0medium000100
ruboxistaurin
1
2007200717.0low000100
idazoxan hydrochloride
1
2007200717.0low000100
isoguvacine hydrochloride
1
2007200717.0low000100
8-methoxymethyl-3-isobutyl-1-methylxanthine
1
oxopurine2007200717.0low000100
cyc 202
2
2,6-diaminopurinesantiviral drug;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor		2007200717.0low000200
Serotonin hydrochloride
1
tryptamines2007200717.0low000100
n-phthaloylglutamic acid
1
L-glutamic acid derivative;
phthalimides		2007200717.0low000100
1,3-dipropyl-7-methylxanthine
1
2007200717.0low000100
ag 3-5
1
C-nitro compound2007200717.0low000100
n-n-propylnorapomorphine
1
aporphine alkaloid2007200717.0low000100
urapidil monohydrochloride
1
2007200717.0low000100
aminopterin
1
dicarboxylic acidEC 1.5.1.3 (dihydrofolate reductase) inhibitor;
mutagen		2007200717.0low000100
azepexole, dihydrochloride
1
2007200717.0low000100
2,5-dimethoxy-4-iodoamphetamine hydrochloride
1
2007200717.0medium000100
abt 980
1
2007200717.0low000100
sk&f 75670
1
2007200717.0low000100
esatenolol
1
atenololbeta-adrenergic antagonist2007200717.0low000100
sb 203580
1
imidazoles;
monofluorobenzenes;
pyridines;
sulfoxide		EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent		2007200717.0low000100
nbi 27914
1
dialkylarylamine;
tertiary amino compound		2007200717.0low000100
sb 216763
1
indoles;
maleimides		2007200717.0low000100
erlotinib
1
aromatic ether;
quinazolines;
secondary amino compound;
terminal acetylenic compound		antineoplastic agent;
epidermal growth factor receptor antagonist;
protein kinase inhibitor		2007200717.0low000100
(R)-atenolol
1
atenolol2007200717.0low000100
memantine hydrochloride
1
hydrochlorideantidepressant;
antiparkinson drug;
dopaminergic agent;
neuroprotective agent;
NMDA receptor antagonist		2007200717.0low000100
pefabloc
1
2007200717.0low000100
pongidae
1
2007200717.0medium000100
succinylproline
1
N-acyl-amino acid2007200717.0low000100
sb 205384
1
thienopyridine2007200717.0low000100
hydrastine
1
isoquinolinesmetabolite2007200717.0low000100
gabaculine hydrochloride
1
2007200717.0medium000100
etiron monohydrobromide
1
2007200717.0medium000100
bmy 7378
1
2007200717.0low000100
vesamicol
1
2007200717.0medium000100
cortisone
1
11-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite		2007200717.0low000100
vincristine sulfate
1
organic sulfate saltantineoplastic agent;
geroprotector		2007200717.0low000100
n-methylserotonin oxalate salt
1
2007200717.0medium000100
nsc 95397
1
1,4-naphthoquinones2007200717.0low000100
wortmannin
1
acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound		anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent		2007200717.0low000100
5-iodoindirubin-3'-monoxime
1
2007200717.0medium000100
lithium chloride
1
inorganic chloride;
lithium salt		antimanic drug;
geroprotector		2007200717.0low000100
2H-pyrazolo[4,3-b]quinoxalin-3-amine
1
quinoxaline derivative2007200717.0medium000100
canavanine
1
amino acid zwitterion;
non-proteinogenic L-alpha-amino acid		phytogenic insecticide;
plant metabolite		2007200717.0low000100
5-hydroxytryptophan
1
5-hydroxytryptophan;
amino acid zwitterion;
hydroxy-L-tryptophan;
non-proteinogenic L-alpha-amino acid		human metabolite;
mouse metabolite;
plant metabolite		2007200717.0low000100
ouabain
1
11alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite		2007200717.0low000100
tosylphenylalanyl chloromethyl ketone
1
alpha-chloroketone;
sulfonamide		alkylating agent;
serine proteinase inhibitor		2007200717.0low000100
monoiodotyrosine
1
amino acid zwitterion;
L-tyrosine derivative;
monoiodotyrosine;
non-proteinogenic L-alpha-amino acid		EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor;
human metabolite;
mouse metabolite		2007200717.0low000100
nitroarginine
1
guanidines;
L-arginine derivative;
N-nitro compound;
non-proteinogenic L-alpha-amino acid		2007200717.0low000100
willardiine
1
amino acid zwitterion;
L-alanine derivative;
non-proteinogenic L-alpha-amino acid		2007200717.0low000100
cortodoxone
1
deoxycortisol;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite		2007200717.0low000100
amiodarone hydrochloride
1
aromatic ketone2007200717.0low000100
dicyclomine hydrochloride
1
hydrochlorideantispasmodic drug;
muscarinic antagonist		2007200717.0low000100
metyrosine
1
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		antihypertensive agent;
EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor		2007200717.0low000100
nortriptyline hydrochloride
1
organic tricyclic compoundgeroprotector2007200717.0low000100
paromomycin sulfate
1
2007200717.0medium000100
Dubinidine
1
organic heterotricyclic compound;
organonitrogen heterocyclic compound;
oxacycle		2007200717.0low000100
cyclopamine
1
piperidinesglioma-associated oncogene inhibitor2007200717.0low000100
s-(4-azidophenacyl)glutathione
1
peptide2007200717.0low000100
hydroxylamine hydrochloride
1
organic molecular entity2007200717.0medium000100
sb 228357
1
indolyl carboxylic acid2007200717.0medium000100
3,5-dihydroxyphenylglycine
1
amino acid zwitterion;
non-proteinogenic L-alpha-amino acid;
resorcinols		2007200717.0low000100
actinonin
1
2007200717.0low000100
vinpocetine
1
alkaloidgeroprotector2007200717.0low000100
dihydroergocristine monomesylate
1
methanesulfonate saltalpha-adrenergic antagonist;
geroprotector;
vasodilator agent		2007200717.0low000100
tretinoin
1
retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule		2007200717.0low000100
resveratrol
1
resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger		2007200717.0low000100
oleic acid
1
octadec-9-enoic acidantioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent		2007200717.0low000100
thapsigargin
1
butyrate ester;
organic heterotricyclic compound;
sesquiterpene lactone		calcium channel blocker;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor		2007200717.0low000100
brivudine
1
2007200717.0low000100
5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
1
carbotetracyclic compound;
polyphenol		estrogen receptor agonist;
estrogen receptor antagonist;
geroprotector;
neuroprotective agent		2007200717.0low000100
2-amino-3-(5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl)propionic acid
1
2007200717.0medium000100
n-(4-methoxybenzyl)-n'-(5-nitro-1,3-thiazol-2-yl)urea
1
2007200717.0low000100
y 27632
2
aromatic amide2007201015.5low000200
h 1152
1
isoquinolines;
N-sulfonyldiazepane		EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor2007200717.0medium000100
adenosine-5'-(n-ethylcarboxamide)
1
adenosines;
monocarboxylic acid amide		adenosine A1 receptor agonist;
adenosine A2A receptor agonist;
antineoplastic agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
vasodilator agent		2007200717.0low000100
7-n-butyl-6-(4'-hydroxyphenyl)-5h-pyrrolo(2,3b)pyrazine
1
2007200717.0medium000100
6-bromoindirubin-3'-oxime
1
2007200717.0low000100
L-cycloserine
1
4-amino-1,2-oxazolidin-3-oneanti-HIV agent;
anticonvulsant;
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor		2007200717.0low000100
h 89
1
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide2007200717.0low000100
1,4-dideoxy-1,4-imino-d-arabinitol
1
2007200717.0low000100
purvalanol a
2
purvalanol2007200717.0low000200
melphalan
1
L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent		2007200717.0low000100
2-methyl-5-(4-methylanilino)-1,3-benzothiazole-4,7-dione
1
aminotoluene2007200717.0medium000100
isoliquiritigenin
1
chalconesantineoplastic agent;
biological pigment;
EC 1.14.18.1 (tyrosinase) inhibitor;
GABA modulator;
geroprotector;
metabolite;
NMDA receptor antagonist		2007200717.0low000100
rauwolscine
1
methyl 17-hydroxy-20xi-yohimban-16-carboxylate2007200717.0low000100
gw9662
1
benzamides2007200717.0low000100
calmidazolium
1
organic chloride saltapoptosis inducer;
calmodulin antagonist		2007200717.0low000100
tropisetron hydrochloride
1
2007200717.0medium000100
Reactive blue 2
1
anthraquinone2007200717.0medium000100
5,6-dichloro-1-ethyl-1,3-dihydro-2h-benzimidazol-2-one
1
dichlorobenzene2007200717.0low000100
quinidine sulfate
1
2007200717.0medium000100
ipratropium bromide anhydrous
1
2007200717.0low000100
methamilane methiodide
1
2007200717.0medium000100
pilocarpine nitrate
1
2007200717.0low000100
r 59949
2
diarylmethane2007200717.0low000200
n(6)-cyclopentyladenosine
1
2007200717.0low000100
methylatropine nitrate
1
2007200717.0low000100
sb 366791
1
2007200717.0low000100
ag-213
1
2007200717.0low000100
3,3',4,5'-tetrahydroxystilbene
2
catechols;
polyphenol;
resorcinols;
stilbenol		antineoplastic agent;
apoptosis inducer;
geroprotector;
hypoglycemic agent;
plant metabolite;
protein kinase inhibitor;
tyrosine kinase inhibitor		2007200717.0low000200
bemesetron
1
2007200717.0low000100
(S)-(-)-pindolol
1
pindolol2007200717.0low000100
levosulpiride
1
sulpirideantidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist		2007200717.0low000100
caffeic acid
1
caffeic acidgeroprotector;
mouse metabolite		2007200717.0low000100
4-fluorophenyl-L-alanine
1
4-fluorophenylalanine;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid		2007200717.0low000100
urocanic acid
1
urocanic acidhuman metabolite2007200717.0low000100
cotinine
1
N-alkylpyrrolidine;
pyridines;
pyrrolidin-2-ones;
pyrrolidine alkaloid		antidepressant;
biomarker;
human xenobiotic metabolite;
plant metabolite		2007200717.0low000100
cinnarizine
1
diarylmethane;
N-alkylpiperazine;
olefinic compound		anti-allergic agent;
antiemetic;
calcium channel blocker;
geroprotector;
H1-receptor antagonist;
histamine antagonist;
muscarinic antagonist		2007200717.0low000100
sulindac
1
monocarboxylic acid;
organofluorine compound;
sulfoxide		analgesic;
antineoplastic agent;
antipyretic;
apoptosis inducer;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug;
tocolytic agent		2007200717.0low000100
cysteine sulfinic acid
1
organosulfinic acid;
S-substituted L-cysteine		Escherichia coli metabolite;
human metabolite;
metabotropic glutamate receptor agonist;
mouse metabolite		2007200717.0low000100
d-ap7
1
2007200717.0medium000100
tg 003
1
2007200717.0low000100
(1R,2S)-tranylcypromine hydrochloride
1
hydrochloride2007200717.0low000100
tacrine hydrochloride
1
2007200717.0low000100
thiourea
1
one-carbon compound;
thioureas;
ureas		antioxidant;
chromophore		2007200717.0low000100
4-bromotetramisole, oxalate (1:1), salt(s)-isomer
1
2007200717.0medium000100
3-hydroxybenzylhydrazine hydrochloride
1
2007200717.0medium000100
1-(3-chlorophenyl)biguanide hydrochloride
1
2007200717.0medium000100
4-chlorophenylalanine methyl ester, hydrochloride, (dl)-isomer
1
2007200717.0medium000100
capsazepine
1
benzazepine;
catechols;
monochlorobenzenes;
thioureas		capsaicin receptor antagonist2007200717.0low000100
diphenyleneiodium chloride
1
organic chloride saltEC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor;
G-protein-coupled receptor agonist		2007200717.0low000100
azetidine-2,4-dicarboxylic acid, (cis)-isomer
1
2007200717.0medium000100
tamoxifen citrate
1
citrate saltangiogenesis inhibitor;
anticoronaviral agent		2007200717.0low000100
pimagedine hydrochloride
1
2007200717.0medium000100
Betaine Aldehyde Chloride
1
quaternary ammonium salt2007200717.0medium000100
eskazine
1
2007200717.0low000100
monastrol
1
enoate ester;
ethyl ester;
phenols;
racemate;
thioureas		antileishmanial agent;
antimitotic;
antineoplastic agent;
EC 3.5.1.5 (urease) inhibitor		2007200717.0low000100
u 0126
2
aryl sulfide;
dinitrile;
enamine;
substituted aniline		antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
osteogenesis regulator;
vasoconstrictor agent		2007200717.0low000200
4-diphenylacetoxy-n-methylpiperidine methiodide
1
iodide salt;
quaternary ammonium salt		cholinergic antagonist;
muscarinic antagonist		2007200717.0low000100
1-(4-hydroxybenzyl)imidazole-2-thiol
1
2007200717.0low000100
2-chloro-n(6)-(3-iodobenzyl)adenosine-5'-n-methyluronamide
1
2007200717.0low000100
bp 897
1
naphthalenecarboxamide2007200717.0low000100
trequinsin hydrochloride
1
2007200717.0low000100
dasatinib
1
1,3-thiazoles;
aminopyrimidine;
monocarboxylic acid amide;
N-(2-hydroxyethyl)piperazine;
N-arylpiperazine;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antineoplastic agent;
tyrosine kinase inhibitor		2007200717.0low000100
neboglamine
1
2007200717.0low000100
benzatropine methanesulfonate
1
2007200717.0medium000100
sb 203186
1
indolyl carboxylic acid2007200717.0medium000100
n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)urea
1
1,2-thiazoles;
indoles;
ureas		receptor modulator;
serotonergic antagonist		2007200717.0low000100
gtp 14564
1
pyrazoles;
ring assembly		2007200717.0medium000100
sb 218078
1
indolocarbazole2007200717.0low000100
gw 7647
1
aryl sulfide;
monocarboxylic acid;
ureas		PPARalpha agonist2007200717.0low000100
ro 41-0960
1
2007200717.0low000100
cgp 13501
1
alkylbenzene2007200717.0low000100
n-(2-(4-(4-chlorophenyl)piperazin-1-yl)ethyl)-3-methoxybenzamide
1
2007200717.0low000100
brl 15572
1
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
secondary alcohol		geroprotector;
serotonergic antagonist		2007200717.0low000100
mrs 1523
1
2007200717.0low000100
or486
1
2007200717.0low000100
fg 9041
1
quinoxaline derivative2007200717.0low000100
iik7
1
2007200717.0low000100
sb 415286
1
C-nitro compound;
maleimides;
monochlorobenzenes;
phenols;
secondary amino compound;
substituted aniline		antioxidant;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
neuroprotective agent		2007200717.0low000100
dm 235
1
2007200717.0low000100
jhw 015
1
indolecarboxamide2007200717.0low000100
bw 723c86
1
tryptamines2007200717.0low000100
sc 560
1
aromatic ether;
monochlorobenzenes;
organofluorine compound;
pyrazoles		angiogenesis modulating agent;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 1 inhibitor;
non-steroidal anti-inflammatory drug		2007200717.0low000100
sc-19220
1
aromatic ether2007200717.0low000100
le 300
1
indoles2007200717.0low000100
ly 367265
1
dihydropyridine;
fluoroindole;
tertiary amino compound;
thiadiazoloquinoline		antidepressant;
geroprotector;
serotonergic antagonist;
serotonin uptake inhibitor		2007200717.0low000100
alsterpaullone
1
C-nitro compound;
caprolactams;
organic heterotetracyclic compound		anti-HIV-1 agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor		2007200717.0low000100
diclofenac sodium
1
organic sodium salt2007200717.0low000100
cgp 7930
1
alkylbenzene2007200717.0low000100
1,3,5-tris(4-hydroxyphenyl)-4-propyl-1h-pyrazole
1
phenols;
pyrazoles		estrogen receptor agonist2007200717.0low000100
sib 1757
1
2007200717.0low000100
sphingosine
1
sphing-4-eninehuman metabolite;
mouse metabolite		2007200717.0low000100
quercetin
1
7-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger		2007200717.0low000100
apigenin
2
trihydroxyflavoneantineoplastic agent;
metabolite		2007200717.0low000200
luteolin
1
3'-hydroxyflavonoid;
tetrahydroxyflavone		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
c-Jun N-terminal kinase inhibitor;
EC 2.3.1.85 (fatty acid synthase) inhibitor;
immunomodulator;
nephroprotective agent;
plant metabolite;
radical scavenger;
vascular endothelial growth factor receptor antagonist		2007200717.0low000100
daphnetin
2
hydroxycoumarin2007200717.0low000200
genistein
2
7-hydroxyisoflavonesantineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor		2007200717.0low000200
pulmicort
1
11beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic acetal;
glucocorticoid;
primary alpha-hydroxy ketone		anti-inflammatory drug;
bronchodilator agent;
drug allergen		2007200717.0low000100
timolol maleate
1
maleate saltanti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist		2007200717.0low000100
brompheniramine maleate
1
maleate saltanti-allergic agent2007200717.0low000100
chlorpheniramine maleate
1
organic molecular entity2007200717.0low000100
clemastine fumarate
1
fumarate saltanti-allergic agent;
antipruritic drug;
H1-receptor antagonist;
muscarinic antagonist		2007200717.0low000100
methylergonovine maleate
1
ergoline alkaloidgeroprotector2007200717.0medium000100
astaxanthine
1
carotenol;
carotenone		animal metabolite;
anticoagulant;
antioxidant;
food colouring;
plant metabolite		2007200717.0low000100
harman
1
harmala alkaloid;
indole alkaloid fundamental parent;
indole alkaloid		anti-HIV agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite		2007200717.0low000100
morin
1
7-hydroxyflavonol;
pentahydroxyflavone		angiogenesis modulating agent;
anti-inflammatory agent;
antibacterial agent;
antihypertensive agent;
antineoplastic agent;
antioxidant;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
hepatoprotective agent;
metabolite;
neuroprotective agent		2007200717.0low000100
myricetin
1
7-hydroxyflavonol;
hexahydroxyflavone		antineoplastic agent;
antioxidant;
cyclooxygenase 1 inhibitor;
food component;
geroprotector;
hypoglycemic agent;
plant metabolite		2007200717.0low000100
daidzein
1
7-hydroxyisoflavonesantineoplastic agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
phytoestrogen;
plant metabolite		2007200717.0low000100
caffeic acid phenethyl ester
1
alkyl caffeate esteranti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiviral agent;
immunomodulator;
metabolite;
neuroprotective agent		2007200717.0low000100
wedelolactone
1
aromatic ether;
coumestans;
delta-lactone;
polyphenol		antineoplastic agent;
apoptosis inducer;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
hepatoprotective agent;
metabolite		2007200717.0low000100
rottlerin
1
aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone		anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite		2007200717.0low000100
flupenthixol
1
flupenthixoldopaminergic antagonist2007200717.0low000100
n-oleoyldopamine
1
catechols;
fatty amide;
N-(fatty acyl)-dopamine;
secondary carboxamide		TRPV1 agonist2007200717.0low000100
pheniramine maleate
1
organic molecular entity2007200717.0low000100
tranilast
1
amidobenzoic acid;
cinnamamides;
dimethoxybenzene;
secondary carboxamide		anti-allergic agent;
anti-asthmatic drug;
antineoplastic agent;
aryl hydrocarbon receptor agonist;
calcium channel blocker;
hepatoprotective agent;
nephroprotective agent		2007200717.0low000100
trimipramine maleate
1
maleate saltantidepressant2007200717.0low000100
isotretinoin
1
retinoic acidantineoplastic agent;
keratolytic drug;
teratogenic agent		2007200717.0low000100
xylometazoline hydrochloride
1
2007200717.0low000100
flunarizine hydrochloride
1
diarylmethane2007200717.0low000100
ketotifen fumarate
1
organoammonium saltanti-asthmatic drug;
H1-receptor antagonist		2007200717.0low000100
cis-flupenthixol dihydrochloride
1
hydrochloridegeroprotector2007200717.0medium000100
n-arachidonylglycine
1
fatty amide;
N-acylglycine		2007200717.0low000100
n-oleoylethanolamine
1
endocannabinoid;
N-(long-chain-acyl)ethanolamine;
N-acylethanolamine 18:1		EC 3.5.1.23 (ceramidase) inhibitor;
geroprotector;
PPARalpha agonist		2007200717.0low000100
cyclosporine
1
homodetic cyclic peptideanti-asthmatic drug;
anticoronaviral agent;
antifungal agent;
antirheumatic drug;
carcinogenic agent;
dermatologic drug;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
geroprotector;
immunosuppressive agent;
metabolite		2007200717.0low000100
phenoxybenzamine hydrochloride
1
organic molecular entity2007200717.0low000100
phenylephrine hydrochloride
1
hydrochloride2007200717.0low000100
mepyramine maleate
1
2007200717.0low000100
brefeldin a
1
macrolide antibioticPenicillium metabolite2007200717.0low000100
fenretinide
1
monocarboxylic acid amide;
retinoid		antineoplastic agent;
antioxidant		2007200717.0low000100
geldanamycin
1
1,4-benzoquinones;
ansamycin;
carbamate ester;
organic heterobicyclic compound		antimicrobial agent;
antineoplastic agent;
antiviral agent;
cysteine protease inhibitor;
Hsp90 inhibitor		2007200717.0low000100
su 9516
1
2007200717.0low000100
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid
1
benzoic acids;
naphthalenes;
retinoid		antineoplastic agent;
retinoic acid receptor agonist;
teratogenic agent		2007200717.0low000100
l-2-(carboxypropyl)glycine
1
2007200717.0low000100
4-aminocrotonic acid
1
2007200717.0low000100
denopamine
1
dimethoxybenzene2007200717.0low000100
l 655,708
1
2007200717.0low000100
ro 41-1049
1
2007200717.0low000100
sb 200646a
1
2007200717.0medium000100
seglitide
1
2007200717.0low000100
sib 1893
1
2007200717.0low000100
kn 93
1
monochlorobenzenes;
monomethoxybenzene;
primary alcohol;
sulfonamide;
tertiary amino compound		EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor;
geroprotector		2007200717.0low000100
su 6656
2
2007200717.0low000200
tyrphostin ag 555
1
2007200717.0low000100
tyrphostin ag-494
2
2007200717.0low000200
tyrphostin b44
1
2007200717.0low000100
ag-490
2
catechols;
enamide;
monocarboxylic acid amide;
nitrile;
secondary carboxamide		anti-inflammatory agent;
antioxidant;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector;
STAT3 inhibitor		2007200717.0low000200
ag 112
1
2007200717.0low000100
ag 183
1
2007200717.0low000100
semaxinib
1
olefinic compound;
oxindoles;
pyrroles		angiogenesis modulating agent;
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
vascular endothelial growth factor receptor antagonist		2007200717.0low000100
su 11248
1
monocarboxylic acid amide;
pyrroles		angiogenesis inhibitor;
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
immunomodulator;
neuroprotective agent;
vascular endothelial growth factor receptor antagonist		2007200717.0low000100
su 11652
1
olefinic compound;
organochlorine compound;
oxindoles;
pyrrolecarboxamide;
tertiary amino compound		EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor		2007200717.0low000100
8-(3-chlorostyryl)caffeine
1
monochlorobenzenes;
trimethylxanthine		adenosine A2A receptor antagonist;
EC 1.4.3.4 (monoamine oxidase) inhibitor		2007200717.0low000100
bay 11-7085
1
benzenes;
nitrile;
sulfone		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
ferroptosis inducer;
NF-kappaB inhibitor		2007200717.0low000100
molsidomine
1
ethyl ester;
morpholines;
oxadiazole;
zwitterion		antioxidant;
apoptosis inhibitor;
cardioprotective agent;
nitric oxide donor;
vasodilator agent		2007200717.0low000100
diamide
1
1,1'-azobis(N,N-dimethylformamide)2007200717.0low000100
nomifensine maleate
1
2007200717.0low000100
nalbuphine hydrochloride
1
hydrochloride2007200717.0low000100
isoalloxazine
1
benzo[g]pteridine-2,4-dione2007200717.0low000100
vinblastine sulfate
1
2007200717.0low000100
n-methylscopolamine bromide
1
2007200717.0low000100
dextromethorphan hydrobromide
1
hydrate;
hydrobromide		2007200717.0low000100
naloxone hydrochloride
1
hydrochlorideantidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist		2007200717.0low000100
s-trans,trans-farnesylthiosalicylic acid
1
sesquiterpenoid2007200717.0low000100
sulindac sulfone
1
monocarboxylic acid;
organofluorine compound;
sulfone		apoptosis inducer;
cyclooxygenase 2 inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor		2007200717.0low000100
naltrexone hydrochloride
1
hydrochlorideantidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist		2007200717.0low000100
2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz(h)imidazo(4,5-f)isoquinoline-7-one
1
organic heterotetracyclic compound;
organofluorine compound		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor2007200717.0low000100
guanabenz acetate
1
dichlorobenzenegeroprotector2007200717.0low000100
nylidrin hydrochloride
1
alkylbenzene2007200717.0low000100
triprolidine hydrochloride anhydrous
1
hydrochlorideH1-receptor antagonist2007200717.0low000100
famotidine
1
1,3-thiazoles;
guanidines;
sulfonamide		anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor		2007200717.0low000100
fenoterol
1
hydrobromidebeta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent		2007200717.0low000100
tiapridex
1
benzamides2007200717.0low000100
quipazine maleate
1
2007200717.0low000100
n-(2-aminoethyl)-4-chlorobenzamide hydrochloride
1
2007200717.0low000100
tulobuterol hydrochloride
1
organic molecular entity2007200717.0low000100
hp 029
1
2007200717.0low000100
n,n,n-trimethyl-1-(4-stilbenoxy)-2-propylammonium iodide
1
2007200717.0medium000100
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-one
1
naphthalenes2007200717.0low000100
st 638
1
2007200717.0low000100
su 1498
1
enamide;
monocarboxylic acid amide;
nitrile;
phenols;
secondary carboxamide		vascular endothelial growth factor receptor antagonist2007200717.0low000100
nf023
1
2007200717.0medium000100
nf 449
1
2007200717.0medium000100
7-chloro-4-hydroxy-2-phenyl-1,8-naphthyridine
1
2007200717.0low000100
gr 46611
1
2007200717.0low000100
monorden
1
cyclic ketone;
enone;
epoxide;
macrolide antibiotic;
monochlorobenzenes;
phenols		antifungal agent;
metabolite;
tyrosine kinase inhibitor		2007200717.0low000100
diacetylmonoxime
1
2007200717.0low000100
ml 3403
1
2007200717.0medium000100
d 4476
1
imidazoles2007200717.0low000100
GSK3-XIII
1
aromatic amine;
pyrazoles;
quinazolines;
secondary amino compound		EC 2.7.11.26 (tau-protein kinase) inhibitor2007200717.0low000100
homatropine hydrobromide, (endo-(+-)-isomer)
1
2007200717.0low000100
vancomycin hydrochloride
1
2007200717.0low000100
moxisylyte hydrochloride
1
monoterpenoid2007200717.0low000100
dizocilpine maleate
1
maleate salt;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist		2007200717.0low000100
beta-aminopropionitrile fumarate
1
2007200717.0low000100
flupirtine
1
2007200717.0low000100
zimelidine hydrochloride
1
2007200717.0medium000100
pregna-4,17-diene-3,16-dione, (17z)-isomer
1
2007200717.0low000100
su 4312
1
2007200717.0low000100
gw 1929
1
benzophenones2007200717.0low000100
2-[(3-iodophenyl)methylthio]-5-pyridin-4-yl-1,3,4-oxadiazole
1
aryl sulfide2007200717.0medium000100
protriptyline hydrochloride
1
hydrochlorideantidepressant2007200717.0low000100
n(4)-chloroacetylcytosine arabinoside
1
2007200717.0low000100
n-(3-(cyclohexylidene-(1h-imidazol-4-ylmethyl))phenyl)ethanesulfonamide
1
2007200717.0low000100
n-(4-amino-2-chlorophenyl)phthalimide
1
2007200717.0low000100
cb 34
1
2007200717.0low000100
b 43
1
aromatic amine;
aromatic ether;
cyclopentanes;
primary amino compound;
pyrrolopyrimidine		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector		2007200717.0low000100
(8R)-7-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol
1
aporphine alkaloid2007200717.0low000100
(8R)-7-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol
1
aporphine alkaloid2007200717.0low000100
3-(6-chloro-3-pyridazinyl)-3,8-diazabicyclo(3.2.1)octane
1
2007200717.0medium000100
2-(3,3-diphenylpropylamino)acetamide
1
diarylmethane2007200717.0low000100
4-(2-(phenylsulfonylamino)ethylthio)-2,6-difluorophenoxyacetamide
1
2007200717.0low000100
gw2974
1
pyridopyrimidine2007200717.0low000100
l 162313
1
2007200717.0low000100
l-165041
1
aromatic ketone2007200717.0low000100
mrs 1754
1
oxopurine2007200717.0low000100
s-nitroso-n-acetylpenicillamine
1
nitroso compound;
nitrosothio compound		nitric oxide donor;
vasodilator agent		2007200717.0low000100
pd 404182
1
2007200717.0medium000100
sb 222200
1
quinolines2007200717.0low000100
dantrolene sodium
1
2007200717.0low000100
cr 2945
1
2007200717.0low000100
sb 218795
1
quinolines2007200717.0low000100
aminopurvalanol a
1
monochlorobenzenes;
purvalanol		protein kinase inhibitor2007200717.0medium000100
dihydroceramide
1
N-acylsphinganine2007200717.0medium000100
epinephrine bitartrate
1
2007200717.0low000100
bicuculline methobromide
1
2007200717.0low000100
butylscopolammonium bromide
1
2007200717.0low000100
butaclamol hydrochloride
1
2007200717.0low000100
a 38503
1
2007200717.0low000100
8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide
1
2007200717.0low000100
sk&f 89976-a
1
2007200717.0low000100
cv 1808
1
purine nucleoside2007200717.0low000100
cvt 313
1
2007200717.0low000100
bibx 1382bs
1
substituted aniline2007200717.0low000100
sl 327
1
2007200717.0low000100
tws 119
1
pyrroles2007200717.0low000100
krn 633
1
2007200717.0low000100
((3z)-n-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1h-pyrrol-2-yl)methylene)-n-methyl-2-oxo-2,3-dihydro-1h-indole-5-sulfonamide)
1
sulfonamide2007200717.0low000100
c 1368
1
2007200717.0medium000100
pq 401
1
quinolines2007200717.0low000100
fluvoxamine maleate
1
(trifluoromethyl)benzenes2007200717.0low000100
naloxone benzoylhydrazone
1
2007200717.0low000100
2-methyl-6-(phenylethynyl)pyridine hydrochloride
1
hydrochlorideanxiolytic drug;
metabotropic glutamate receptor antagonist		2007200717.0low000100
jnj 10198409
1
2007200717.0medium000100
amiprilose
1
2007200717.0medium000100
(R)-fluoxetine hydrochloride
1
hydrochlorideantidepressant;
serotonin uptake inhibitor		2007200717.0medium000100
desmethylselegiline hydrochloride
1
2007200717.0medium000100
3-morpholino-sydnonimine monohydrochloride
1
2007200717.0low000100
nu 7026
1
organic heterotricyclic compound;
organooxygen compound		2007200717.0low000100
ripasudil
1
isoquinolines202020204.0medium000010
t 1032
1
2007200717.0low000100
qx-314 bromide
1
2007200717.0medium000100
(S)-fluoxetine hydrochloride
1
hydrochlorideantidepressant;
serotonin uptake inhibitor		2007200717.0medium000100
pi103
1
aromatic amine;
morpholines;
organic heterotricyclic compound;
phenols;
tertiary amino compound		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor		2007200717.0low000100
sr 59230a
1
2007200717.0low000100
u 74389g
1
2007200717.0medium000100
1-(2-methoxyphenyl)piperazine hydrochloride
1
2007200717.0low000100
noscapine hydrochloride
1
2007200717.0medium000100
a 77636
1
hydrochlorideantiparkinson drug;
dopamine agonist		2007200717.0medium000100
cgp 20712a
1
2007200717.0low000100
levodopa methyl ester hydrochloride
1
2007200717.0low000100
benalfocin hydrochloride
1
2007200717.0medium000100
lu 19005
1
2007200717.0medium000100
benoxathian hydrochloride
1
2007200717.0medium000100
((2-n-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1h-inden-5-yl)oxy)acetic acid, (+)-isomer
1
2007200717.0low000100
n-cyclopropyl adenosine-5'-carboxamide
1
2007200717.0low000100
cefotaxime sodium
1
organic sodium salt2007200717.0low000100
calpain inhibitor iii
1
2007200717.0low000100
fr 180204
1
pyrazoles;
ring assembly		2007200717.0low000100
GR 127935 hydrochloride
1
hydrochlorideserotonergic antagonist2007200717.0medium000100
mrs 1845
1
2007200717.0low000100
gw 2580
1
2007200717.0low000100
1-aminocyclopropane-1-carboxylic acid hydrochloride
1
2007200717.0medium000100
alaproclate hydrochloride
1
2007200717.0medium000100
ubenimex
1
peptide2007200717.0low000100
3-chloroalanine hydrochloride, (l-ala)-isomer
1
2007200717.0medium000100
dsp 4 hydrochloride
1
2007200717.0medium000100
calcimycin
1
benzoxazole2007200717.0low000100
(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzodioxan hydrochloride
1
hydrochloridealpha-adrenergic antagonist2007200717.0low000100
2-cyclooctyl-2-hydroxyethylamine hydrochloride
1
2007200717.0medium000100
cirazoline monohydrochloride
1
2007200717.0medium000100
adtn
1
2007200717.0medium000100
apocodeine hydrochloride, (r)-isomer
1
2007200717.0medium000100
Dihydro-beta-erythroidine hydrobromide
1
indoles2007200717.0medium000100
lilly 78335
1
2007200717.0medium000100
efaroxan hydrochloride
1
2007200717.0low000100
fenoldopam hydrobromide
1
2007200717.0low000100
1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
1
hydrochloridedopamine uptake inhibitor2007200717.0medium000100
guvacine hydrochloride
1
2007200717.0medium000100
7-hydroxy-2-n,n-dipropylaminotetralin hydrobromide
1
2007200717.0low000100
8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide, (r)-isomer,
1
organic molecular entity2007200717.0low000100
1-(2-(4-(4-fluoro-benzoyl)-piperidin-1-yl)-ethyl)-3,3-dimethyl-1,2-dihydro-indol-2-one
1
hydrochloridereceptor modulator;
serotonergic antagonist		2007200717.0low000100
4-iodoclonidine
1
2007200717.0medium000100
4-methylpyrazole monohydrochloride
1
2007200717.0low000100
tele-methylhistamine
1
2007200717.0medium000100
alpha-methyltyrosine methyl ester, monohydrochloride
1
2007200717.0medium000100
octoclothepine maleate
1
2007200717.0low000100
2-(n-phenethyl-n-propyl)amino-5-hydroxytetralin hydrochloride
1
2007200717.0low000100
du 24565
1
2007200717.0medium000100
2-methoxyidazoxan hydrochloride
1
2007200717.0medium000100
ro 25-6981
1
2007200717.0medium000100
sk&f 77434
1
hydrobromidedopamine agonist;
prodrug		2007200717.0low000100
3-[(6aR,9R,10aR)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-yl]-1,1-diethylurea
1
organic heterotetracyclic compound;
organonitrogen heterocyclic compound		2007200717.0medium000100
demethylcantharidin
1
2007200717.0low000100
atropine sulfate
1
2007200717.0low000100
1-deoxynojirimycin hydrochloride
1
2007200717.0medium000100
win 62577
1
2007200717.0medium000100
quinine sulfate
1
hydrate2007200717.0low000100
quercetin
1
2007200717.0low000100
rv 538, (r-(r*,r*))-isomer
1
2007200717.0medium000100
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (1s-cis)-isomer
1
2007200717.0medium000100
valproate sodium
1
organic sodium saltgeroprotector2007200717.0low000100
u 63557a
1
2007200717.0low000100
taurocholic acid, monosodium salt
1
bile salt2007200717.0medium000100
cefmetazole sodium
1
organic sodium saltantimicrobial agent2007200717.0low000100
fusidate sodium
1
2007200717.0medium000100
cephapirin sodium
1
cephalosporin;
organic sodium salt		antibacterial drug2007200717.0low000100
sodium cephalothin
1
organic sodium salt2007200717.0low000100
cefazolin sodium
1
organic sodium salt2007200717.0low000100
5-hydroxydecanoic acid, monosodium salt
1
2007200717.0medium000100
ro13-9904
1
2007200717.0low000100
phenytoin sodium
1
2007200717.0low000100
cr 1409
1
2007200717.0low000100
cortisol succinate, sodium salt
1
organic molecular entity2007200717.0low000100
piroxicam
1
benzothiazine;
monocarboxylic acid amide;
pyridines		analgesic;
antirheumatic drug;
cyclooxygenase 1 inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug		2007200717.0low000100
lfm a13
2
aromatic amide;
dibromobenzene;
enamide;
enol;
nitrile;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 2.7.11.21 (polo kinase) inhibitor;
geroprotector;
platelet aggregation inhibitor		2007200717.0low000200
l 701324
1
quinolines2007200717.0low000100
hispidin
1
2-pyranones;
catechols		antioxidant;
EC 2.7.11.13 (protein kinase C) inhibitor;
fungal metabolite		2007200717.0low000100
minocycline hydrochloride
1
2007200717.0low000100
demeclocycline hydrochloride
1
2007200717.0low000100
acyclovir
1
2-aminopurines;
oxopurine		antimetabolite;
antiviral drug		2007200717.0low000100
sepiapterin
1
sepiapterin2007200717.0low000100
isoxanthopterin
1
dihydroxypteridine2007200717.0low000100
clozapine
1
benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound		adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic		2007200717.0low000100
ganciclovir
1
2-aminopurines;
oxopurine		antiinfective agent;
antiviral drug		2007200717.0low000100
zaprinast
1
triazolopyrimidines2007200717.0low000100
allopurinol
1
nucleobase analogue;
organic heterobicyclic compound		antimetabolite;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
gout suppressant;
radical scavenger		2007200717.0low000100
thiolactomycin
1
2007200717.0low000100
2,4-diaminohypoxanthine
1
hydroxypyrimidine2007200717.0low000100
hymenialdisine
1
2007200717.0low000100
quazinone
1
2007200717.0low000100
isogranulatimide
1
2007200717.0low000100
8-bromocyclic gmp, sodium salt
1
organic sodium saltmuscle relaxant;
protein kinase G agonist		2007200717.0medium000100
ag-879
1
2007200717.0low000100
debromohymenialdisine
1
2007200717.0low000100
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Benign Neoplasms0
1
2007200717.0medium000100
Congenital Zika Syndrome0
1
202020204.0medium000010
Disease Models, Animal0
1
202020204.0medium000010
Neoplasms0
1
2007200717.0medium000100
Sensitivity and Specificity0
1
2007200717.0medium000100
Zika Virus Infection0
1
202020204.0medium000010