3-acrylamidophenylboronic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID Source	ID
PubMed CID	10321331
SCHEMBL ID	235432
MeSH ID	M0378474

Synonyms (33)

Synonym
99349-68-5
3-acrylamidophenylboronic acid
(3-acrylamidophenyl)boronic acid
A846009
(m-acrylamidophenyl)boronic acid
AKOS006291555
3-(acrylamido)phenylboronic acid
FT-0685348
SCHEMBL235432
[3-(prop-2-enoylamino)phenyl]boronic acid
AM808126
boronic acid, b-[3-[(1-oxo-2-propen-1-yl)amino]phenyl]-
3-acrylamido-phenylboronic acid
ULVXDHIJOKEBMW-UHFFFAOYSA-N
(3-acrylamidophenyl)-boronic acid
J-502078
AC-30997
DTXSID50438076
3-(acrylamido)phenylboronic acid, 98%
(m-acrylamido)phenylboronic acid
mfcd09025755
CS-W001006
GS-5726
[3-(prop-2-enamido)phenyl]boronic acid
3-(acryloylamino)benzeneboronic acid
SY066256
3-acrylamidophenylboronic acid (contains varying amounts of anhydride)
3-acrylamidobenzeneboronic acid
(m-acrylamidophenyl)boronicacid
149698-08-8
phenylboronate acrylamide
CS-0067138
(3-acrylamidophenyl)boronicacid

Research Excerpts

Bioavailability

Excerpt	Reference	Relevance
" Mucoadhesive drug delivery systems have the potential to improve topical drug delivery by increasing pharmaceutical bioavailability on the anterior eye surface."	( Phenylboronic-Acid-Based Polymeric Micelles for Mucoadhesive Anterior Segment Ocular Drug Delivery. Kedzior, S; Muirhead, B; Prosperi-Porta, G; Sheardown, H, 2016)	0.43

Dosage Studied

Excerpt	Relevance	Reference
" This novel preparation can enable new combinations of plant extracts and biomaterials to adiministered through NPs or other dosage forms in order to regulate and treat diseases."	( Nanoparticles prepared from pterostilbene reduce blood glucose and improve diabetes complications. Bian, L; Ma, Q; Shi, A; Wu, J; Yan, X; Zhang, P; Zhao, X, 2021)	0.62

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (29)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (17.24)	29.6817
2010's	21 (72.41)	24.3611
2020's	3 (10.34)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 19.24

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	19.24 (24.57)
Research Supply Index	3.40 (2.92)
Research Growth Index	5.01 (4.65)
Search Engine Demand Index	15.26 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (19.24)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	29 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
catechol [no description available]	2.55	2	catechols	allelochemical; genotoxin; plant metabolite
galactose galactopyranose : The pyranose form of galactose.	2.15	1	D-galactose; galactopyranose	Escherichia coli metabolite; mouse metabolite
acrylamide [no description available]	2.03	1	acrylamides; N-acylammonia; primary carboxamide	alkylating agent; carcinogenic agent; Maillard reaction product; mutagen; neurotoxin
acrylic acid acrylic acid: RN given refers to parent cpd. acrylic acid : A alpha,beta-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group.	2.08	1	alpha,beta-unsaturated monocarboxylic acid	metabolite
n,n'-methylenebisacrylamide [no description available]	2.46	2
tetramethoxysilane [no description available]	2.08	1
n-isopropylacrylamide N-isopropylacrylamide: can polymerize with glycidyl acrylate to form reactive water-soluble polymer that can react with the amino groups of enzymes-proteins or other ligands	3.15	5
n,n-dimethylacrylamide [no description available]	7	1
2-(dimethylamino)ethyl methacrylate 2-(dimethylamino)ethyl methacrylate: reducing agent; structure given in first source	2.08	1
pentaerythrityl triacrylate pentaerythrityl triacrylate: acrylate derivative found in ultraviolet curing inks; causes contact dermatitis	2.11	1
(3-mercaptopropyl)trimethoxysilane [no description available]	2.08	1
acetylglucosamine Acetylglucosamine: The N-acetyl derivative of glucosamine.. N-acetyl-beta-D-glucosamine : An N-acetyl-D-glucosamine having beta-configuration at the anomeric centre.	2.07	1	N-acetyl-D-glucosamine	epitope
adenosine quinquefolan B: isolated from roots of Panax quinquefolium L.; RN not in Chemline 10/87; RN from Toxlit	2.11	1	adenosines; purines D-ribonucleoside	analgesic; anti-arrhythmia drug; fundamental metabolite; human metabolite; vasodilator agent
benzeneboronic acid [no description available]	2.15	1	boronic acids
(3-acrylamidopropyl)trimethylammonium chloride [no description available]	2.03	1
n-acetylneuraminic acid N-Acetylneuraminic Acid: An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518). N-acetylneuraminic acid : An N-acylneuraminic acid where the N-acyl group is specified as acetyl.	2	1	N-acetylneuraminic acids	antioxidant; bacterial metabolite; EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; human metabolite; mouse metabolite
maleic acid maleic acid: RN given refers to parent cpd(Z)-isomer which is maleic acid; all RR's given refer to (Z)-isomer; (E)-isomer is fumaric acid. maleic acid : A butenedioic acid in which the double bond has cis- (Z)-configuration.	2.08	1	butenedioic acid	algal metabolite; mouse metabolite; plant metabolite
2-vinyl-4,6-diamino-1,3,5-triazine 2-vinyl-4,6-diamino-1,3,5-triazine: used to create a DNA-imprinted polymer; structure in first source	2.08	1
stilbenes Stilbenes: Organic compounds that contain 1,2-diphenylethylene as a functional group.. trans-stilbene : The trans-isomer of stilbene.	2.31	1	stilbene
ovalbumin Ovalbumin: An albumin obtained from the white of eggs. It is a member of the serpin superfamily.	2.21	1
alizarin red s Alizarin Red S: RN given refers to parent cpd; structure. alizarin red S : An organic sodium salt having 3,4-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate as the counterion. It is commonly used to stain embryo skeletons in cleared whole mounts, usually of small mammals.	2.03	1	organic sodium salt; organosulfonate salt	histological dye
quercetin [no description available]	2.31	1	7-hydroxyflavonol; pentahydroxyflavone	antibacterial agent; antineoplastic agent; antioxidant; Aurora kinase inhibitor; chelator; EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor; geroprotector; phytoestrogen; plant metabolite; protein kinase inhibitor; radical scavenger
pterostilbene [no description available]	2.31	1	diether; methoxybenzenes; stilbenol	anti-inflammatory agent; antineoplastic agent; antioxidant; apoptosis inducer; hypoglycemic agent; neuroprotective agent; neurotransmitter; plant metabolite; radical scavenger
sepharose agarose : A linear polysaccharide made up from alternating D-galactose and 3,6-anhydro-alpha-L-galactopyranose residues joined by alpha-(1->3)- and beta-(1->4)-linkages.	2.31	1
chitosan [no description available]	2.5	2
cyclosporine Cyclosporine: A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).	2.13	1

Condition	Relationship Strength	Studies
Complications of Diabetes Mellitus [description not available]	2.31	1
Alloxan Diabetes [description not available]	2.31	1
Cancer of Liver [description not available]	2.08	1
Liver Neoplasms Tumors or cancer of the LIVER.	2.08	1
Electrolytes Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)	2.1	1
Dry Eye [description not available]	2.13	1
Dry Eye Syndromes Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.	2.13	1
Glycosuria The appearance of an abnormally large amount of GLUCOSE in the urine, such as more than 500 mg/day in adults. It can be due to HYPERGLYCEMIA or genetic defects in renal reabsorption (RENAL GLYCOSURIA).	2.13	1
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	2.13	1
Diabetes Mellitus A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.	2.05	1

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