An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of yeast. [PRO:DNx]
EC 2.3.1.286;
Homologous to SIR2 protein 2;
Regulatory protein SIR2 homolog 2
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| niacinamide | Saccharomyces cerevisiae S288C | IC50 | 91.0000 | 1 | 1 |
| ro 31-8220 | Saccharomyces cerevisiae S288C | IC50 | 20.0000 | 1 | 1 |
| fenofibrate | Saccharomyces cerevisiae S288C | IC50 | 600.0000 | 1 | 1 |
| suramin | Saccharomyces cerevisiae S288C | IC50 | 240.0000 | 1 | 1 |
| surfactin c | Saccharomyces cerevisiae S288C | IC50 | 700.0000 | 1 | 1 |
| sirtinol | Saccharomyces cerevisiae S288C | IC50 | 48.0000 | 1 | 1 |
| cambinol | Saccharomyces cerevisiae S288C | IC50 | 1,000.0000 | 1 | 1 |
| tenovin-6 | Saccharomyces cerevisiae S288C | IC50 | 100.0000 | 1 | 1 |