Page last updated: 2024-09-22

propanoldiaminetetracetic acid

Cross-References

ID SourceID
PubMed CID20442
CHEMBL ID3246005
SCHEMBL ID21228
SCHEMBL ID10825921
MeSH IDM0139553

Synonyms (47)

Synonym
glycine, n,n'-(1-methyl-1,2-ethanediyl)bis(n-(carboxymethyl)-
brn 2223855
propane-1,2-dinitrilotetraacetic acid
propylenediamine tetra-acetic acid
ccris 1250
pdta
medta
1,2-propylenediaminetetraacetic acid
1,2-diaminopropanetetraacetic acid
acetic acid, (propylenedinitrilo)tetra-
einecs 224-559-7
propanoldiaminetetracetic acid
1,2-propylenediamine tetraacetic acid
nsc-132341
nsc132341
1,2-diaminopropane-n,n,n',n'-tetraacetic acid, >=98%
D1329
2-[2-[bis(carboxymethyl)amino]propyl-(carboxymethyl)amino]acetic acid
FT-0657928
4408-81-5
propylenediamine-n,n,n',n'-tetraacetic acid
1,2-diaminopropane-n,n,n',n'-tetraacetic acid
methyl-edta
3-04-00-01190 (beilstein handbook reference)
1,2-diaminopropane-n,n,n,n-tetraaceticacid
A826486
FT-0606336
AKOS015893920
CHEMBL3246005
SCHEMBL21228
mfcd00004286
W-106211
1,2-diaminopropane tetraacetic acid
SCHEMBL10825921
1,2-diaminopropane-n,n,n',n'-tetraaceticacid
glycine, n,n'-(1-methyl-1,2-ethanediyl)bis[n-(carboxymethyl)-
2-({1-[bis(carboxymethyl)amino]propan-2-yl}(carboxymethyl)amino)acetic acid
AS-65818
propylenediamine tetraacetic acid
1,2-diaminopropane-n,n,n,n-tetraacetic acid
2,2',2'',2'''-(propane-1,2-diylbis(azanetriyl))tetraacetic acid
AMY16019
D89837
CS-0323146
DTXSID101253702
1,2-diaminopropane-n,n,n inverted exclamation mark ,n inverted exclamation mark -tetraacetic acid
SY050057

Bioassays (11)

Assay IDTitleYearJournalArticle
AID1134121Inhibition of scheduled DNA synthesis in chinese hamster V79-4 cells assessed as DNA synthesis at 10'-5 M measured at 10 hrs by [3H]thymidine uptake /autoradiography (Rvb = 81.7 %)1977Journal of medicinal chemistry, May, Volume: 20, Issue:5
Study of trans-cyclopropylbis (diketopiperazine) and chelating agents related to ICRF 159. Cytotoxicity, mutagenicity, and effects on scheduled and unscheduled DNA synthesis.
AID1134126Induction of scheduled DNA synthesis in chinese hamster V79-4 cells assessed as DNA synthesis at 10'-4 to 10'-5 M measured at 0 to 5 hrs by [3H]thymidine uptake /autoradiography in presence of 2 x 10'-3 M hydroxyurea1977Journal of medicinal chemistry, May, Volume: 20, Issue:5
Study of trans-cyclopropylbis (diketopiperazine) and chelating agents related to ICRF 159. Cytotoxicity, mutagenicity, and effects on scheduled and unscheduled DNA synthesis.
AID1134120Inhibition of scheduled DNA synthesis in chinese hamster V79-4 cells assessed as DNA synthesis at 10'-4 M measured at 10 hrs by [3H]thymidine uptake /autoradiography (Rvb = 81.7 %)1977Journal of medicinal chemistry, May, Volume: 20, Issue:5
Study of trans-cyclopropylbis (diketopiperazine) and chelating agents related to ICRF 159. Cytotoxicity, mutagenicity, and effects on scheduled and unscheduled DNA synthesis.
AID1134103Cytotoxicity against chinese hamster V79-4 cells assessed as survival using 5 x 10'5 cells per plate at 10'-4 M after 24 hrs1977Journal of medicinal chemistry, May, Volume: 20, Issue:5
Study of trans-cyclopropylbis (diketopiperazine) and chelating agents related to ICRF 159. Cytotoxicity, mutagenicity, and effects on scheduled and unscheduled DNA synthesis.
AID1134127Induction of scheduled DNA synthesis in chinese hamster V79-4 cells assessed as DNA synthesis at 10'-3 M measured at 8 hrs by [3H]thymidine uptake /autoradiography in presence of 2 x 10'-3 M hydroxyurea1977Journal of medicinal chemistry, May, Volume: 20, Issue:5
Study of trans-cyclopropylbis (diketopiperazine) and chelating agents related to ICRF 159. Cytotoxicity, mutagenicity, and effects on scheduled and unscheduled DNA synthesis.
AID1134119Inhibition of scheduled DNA synthesis in chinese hamster V79-4 cells assessed as DNA synthesis at 10'-3 M measured at 10 hrs by [3H]thymidine uptake /autoradiography (Rvb = 81.7 %)1977Journal of medicinal chemistry, May, Volume: 20, Issue:5
Study of trans-cyclopropylbis (diketopiperazine) and chelating agents related to ICRF 159. Cytotoxicity, mutagenicity, and effects on scheduled and unscheduled DNA synthesis.
AID1134104Cytotoxicity against chinese hamster V79-4 cells assessed as survival using 1 x 10'5 cells per plate at 10'-4 M after 24 hrs1977Journal of medicinal chemistry, May, Volume: 20, Issue:5
Study of trans-cyclopropylbis (diketopiperazine) and chelating agents related to ICRF 159. Cytotoxicity, mutagenicity, and effects on scheduled and unscheduled DNA synthesis.
AID1134101Cytotoxicity against chinese hamster V79-4 cells assessed as survival using 5 x 10'5 cells per plate at 10'-3 M after 24 hrs1977Journal of medicinal chemistry, May, Volume: 20, Issue:5
Study of trans-cyclopropylbis (diketopiperazine) and chelating agents related to ICRF 159. Cytotoxicity, mutagenicity, and effects on scheduled and unscheduled DNA synthesis.
AID1134106Cytotoxicity against chinese hamster V79-4 cells assessed as survival using 1 x 10'5 cells per plate at 10'-5 M after 24 hrs1977Journal of medicinal chemistry, May, Volume: 20, Issue:5
Study of trans-cyclopropylbis (diketopiperazine) and chelating agents related to ICRF 159. Cytotoxicity, mutagenicity, and effects on scheduled and unscheduled DNA synthesis.
AID1134105Cytotoxicity against chinese hamster V79-4 cells assessed as survival using 5 x 10'5 cells per plate at 10'-5 M after 24 hrs1977Journal of medicinal chemistry, May, Volume: 20, Issue:5
Study of trans-cyclopropylbis (diketopiperazine) and chelating agents related to ICRF 159. Cytotoxicity, mutagenicity, and effects on scheduled and unscheduled DNA synthesis.
AID1134128Induction of scheduled DNA synthesis in chinese hamster V79-4 cells assessed as DNA synthesis at 10'-3 to 10'-5 M measured at 8 hrs by [3H]thymidine uptake /autoradiography in presence of 2 x 10'-3 M hydroxyurea1977Journal of medicinal chemistry, May, Volume: 20, Issue:5
Study of trans-cyclopropylbis (diketopiperazine) and chelating agents related to ICRF 159. Cytotoxicity, mutagenicity, and effects on scheduled and unscheduled DNA synthesis.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (23.08)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's1 (7.69)24.3611
2020's7 (53.85)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other15 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research Highlights

Safety/Toxicity (1)

ArticleYear
Study of trans-cyclopropylbis (diketopiperazine) and chelating agents related to ICRF 159. Cytotoxicity, mutagenicity, and effects on scheduled and unscheduled DNA synthesis.
Journal of medicinal chemistry, Volume: 20, Issue: 5
1977
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (1)

ArticleYear
Magnetic field dependence of proton relaxation rates in tissue with added Mn2+: rabbit liver and kidney.
Magnetic resonance in medicine, Volume: 2, Issue: 2
1985
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]