| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Congenital Zika Syndrome
[description not available] | 0 | 2.25 | 1 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 9.6 | 41 | 0 |
Zika Virus Infection
A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME. | 0 | 2.25 | 1 | 0 |
Pleural Effusion
Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. | 0 | 2.6 | 1 | 0 |
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 2.74 | 3 | 0 |
Allergic Contact Dermatitis
[description not available] | 0 | 2.02 | 1 | 0 |
Dermatitis
Any inflammation of the skin. | 0 | 2.02 | 1 | 0 |
Dermatitis, Allergic Contact
A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure. | 0 | 2.02 | 1 | 0 |
Eczema, Atopic
[description not available] | 0 | 2.02 | 1 | 0 |
Itching
[description not available] | 0 | 2.02 | 1 | 0 |
Dermatitis, Atopic
A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema. | 0 | 2.02 | 1 | 0 |
Pruritus
An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief. | 0 | 2.02 | 1 | 0 |
Contact Dermatitis
[description not available] | 0 | 2.38 | 2 | 0 |
Agricultural Worker Disease
[description not available] | 0 | 1.96 | 1 | 0 |
Dermatitis, Contact
A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms. | 0 | 2.38 | 2 | 0 |
Adult Onset Nemaline Myopathy
[description not available] | 0 | 10.55 | 93 | 0 |
Myopathies, Nemaline
A group of inherited congenital myopathic conditions characterized clinically by weakness, hypotonia, and prominent hypoplasia of proximal muscles including the face. Muscle biopsy reveals large numbers of rod-shaped structures beneath the muscle fiber plasma membrane. This disorder is genetically heterogeneous and may occasionally present in adults. (Adams et al., Principles of Neurology, 6th ed, p1453) | 0 | 10.55 | 93 | 0 |
Atrophy, Muscle
[description not available] | 0 | 3.93 | 4 | 0 |
Muscular Atrophy
Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation. | 0 | 3.93 | 4 | 0 |
Muscular Weakness
[description not available] | 0 | 5.29 | 18 | 0 |
Muscle Weakness
A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251) | 0 | 5.29 | 18 | 0 |
Muscle Contraction
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. | 0 | 9.02 | 33 | 0 |
Genetic Predisposition
[description not available] | 0 | 4.69 | 10 | 0 |
Muscle Disorders
[description not available] | 0 | 5.7 | 10 | 0 |
Muscular Diseases
Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE. | 0 | 5.7 | 10 | 0 |
Cancer of the Thyroid
[description not available] | 0 | 2.25 | 1 | 0 |
Thyroid Neoplasms
Tumors or cancer of the THYROID GLAND. | 0 | 2.25 | 1 | 0 |
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 2.74 | 3 | 0 |
Amyoplasia Congenita
[description not available] | 0 | 2.61 | 2 | 0 |
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 3.16 | 5 | 0 |
Disease Exacerbation
[description not available] | 0 | 2.79 | 3 | 0 |
Drooling
[description not available] | 0 | 2.31 | 1 | 0 |
Sialorrhea
Increased salivary flow. | 0 | 2.31 | 1 | 0 |
Aging
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. | 0 | 2.71 | 3 | 0 |
Sarcopenia
Progressive decline in muscle mass due to aging which results in decreased functional capacity of muscles. | 0 | 2.31 | 1 | 0 |
Distal Muscular Dystrophies
[description not available] | 0 | 4.08 | 5 | 0 |
Batten Turner Congenital Myopathy
[description not available] | 0 | 2.63 | 2 | 0 |
Distal Myopathies
A heterogeneous group of genetic disorders characterized by progressive MUSCULAR ATROPHY and MUSCLE WEAKNESS beginning in the hands, the legs, or the feet. Most are adult-onset autosomal dominant forms. Others are autosomal recessive. | 0 | 4.08 | 5 | 0 |
Abnormalities, Multiple
Congenital abnormalities that affect more than one organ or body structure. | 0 | 2.55 | 2 | 0 |
Anesthesia Related Hyperthermia
[description not available] | 0 | 2.15 | 1 | 0 |
Complications, Pregnancy
[description not available] | 0 | 2.15 | 1 | 0 |
Abnormalities, Skin
[description not available] | 0 | 2.15 | 1 | 0 |
Skin Abnormalities
Congenital structural abnormalities of the skin. | 0 | 2.15 | 1 | 0 |
Cystic Kidney Diseases
[description not available] | 0 | 2.15 | 1 | 0 |
Eye Abnormalities
Congenital absence of or defects in structures of the eye; may also be hereditary. | 0 | 2.15 | 1 | 0 |
Concomitant Strabismus
[description not available] | 0 | 2.15 | 1 | 0 |
Strabismus
Misalignment of the visual axes of the eyes. In comitant strabismus the degree of ocular misalignment does not vary with the direction of gaze. In noncomitant strabismus the degree of misalignment varies depending on direction of gaze or which eye is fixating on the target. (Miller, Walsh & Hoyt's Clinical Neuro-Ophthalmology, 4th ed, p641) | 0 | 2.15 | 1 | 0 |
Kidney Diseases, Cystic
A heterogeneous group of hereditary and acquired disorders in which the KIDNEY contains one or more CYSTS unilaterally or bilaterally (KIDNEY, CYSTIC). | 0 | 2.15 | 1 | 0 |
Atrophy
Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes. | 0 | 2.15 | 1 | 0 |
Central Core Disease
[description not available] | 0 | 2.17 | 1 | 0 |
Autosomal Dominant Myotubular Myopathy
[description not available] | 0 | 5.08 | 6 | 0 |
Muscular Dystrophy
[description not available] | 0 | 8.51 | 35 | 0 |
Muscular Dystrophies
A heterogeneous group of inherited MYOPATHIES, characterized by wasting and weakness of the SKELETAL MUSCLE. They are categorized by the sites of MUSCLE WEAKNESS; AGE OF ONSET; and INHERITANCE PATTERNS. | 0 | 8.51 | 35 | 0 |
Blood Pressure, High
[description not available] | 0 | 2.52 | 2 | 0 |
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. | 0 | 2.52 | 2 | 0 |
Cleft Palate, Isolated
[description not available] | 0 | 2.17 | 1 | 0 |
Cleft Palate
Congenital fissure of the soft and/or hard palate, due to faulty fusion. | 0 | 2.17 | 1 | 0 |
Decreased Muscle Tone
[description not available] | 0 | 2.17 | 1 | 0 |
Weight Gain
Increase in BODY WEIGHT over existing weight. | 0 | 2.21 | 1 | 0 |
Hypertrophy
General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA). | 0 | 2.73 | 3 | 0 |
Canine Diseases
[description not available] | 0 | 2.83 | 3 | 0 |
Glaucoma, Angle Closure
[description not available] | 0 | 2.55 | 2 | 0 |
Glaucoma, Angle-Closure
A form of glaucoma in which the intraocular pressure increases because the angle of the anterior chamber is blocked and the aqueous humor cannot drain from the anterior chamber. | 0 | 2.55 | 2 | 0 |
Cardiomyopathies, Primary
[description not available] | 0 | 2.5 | 2 | 0 |
Amyotonia Congenita
[description not available] | 0 | 2.21 | 1 | 0 |
Cardiomyopathies
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS). | 0 | 2.5 | 2 | 0 |
Neuromuscular Diseases
A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA. | 0 | 2.21 | 1 | 0 |
Autolysis
The spontaneous disintegration of tissues or cells by the action of their own autogenous enzymes. | 0 | 2.52 | 2 | 0 |
Cirrhosis, Liver
[description not available] | 0 | 2.08 | 1 | 0 |
Liver Cirrhosis
Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. | 0 | 2.08 | 1 | 0 |
Becker Muscular Dystrophy
[description not available] | 0 | 2.1 | 1 | 0 |
Muscular Dystrophy, Duchenne
An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415) | 0 | 2.1 | 1 | 0 |
Adipocere
[description not available] | 0 | 4.14 | 16 | 0 |
Aura
[description not available] | 0 | 2.1 | 1 | 0 |
Deficiency, Mental
[description not available] | 0 | 2.1 | 1 | 0 |
Epilepsy
A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) | 0 | 2.1 | 1 | 0 |
Intellectual Disability
Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28) | 0 | 2.1 | 1 | 0 |
Cardiomyopathy, Congestive
[description not available] | 0 | 3.03 | 1 | 0 |
Cardiomyopathy, Dilated
A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein. | 0 | 3.03 | 1 | 0 |
Cirrhosis
[description not available] | 0 | 2.11 | 1 | 0 |
Fibrosis
Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury. | 0 | 2.11 | 1 | 0 |
Ambulation Disorders, Neurologic
[description not available] | 0 | 2.11 | 1 | 0 |
Disease
A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown. | 0 | 3.04 | 1 | 0 |
Cardiac Diseases
[description not available] | 0 | 3.04 | 1 | 0 |
Heart Diseases
Pathological conditions involving the HEART including its structural and functional abnormalities. | 0 | 3.04 | 1 | 0 |
Exertional Heat Illness
[description not available] | 0 | 2.13 | 1 | 0 |
Pyrexia
[description not available] | 0 | 2.13 | 1 | 0 |
Fever
An abnormal elevation of body temperature, usually as a result of a pathologic process. | 0 | 2.13 | 1 | 0 |
Acute Hypercapnic Respiratory Failure
[description not available] | 0 | 2.55 | 2 | 0 |
Respiratory Insufficiency
Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) | 0 | 2.55 | 2 | 0 |
Autosomal Chromosome Disorders
[description not available] | 0 | 2.04 | 1 | 0 |
Alloxan Diabetes
[description not available] | 0 | 2.05 | 1 | 0 |
Leucocythaemia
[description not available] | 0 | 2.05 | 1 | 0 |
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) | 0 | 2.05 | 1 | 0 |
Deafness, Transitory
[description not available] | 0 | 2.07 | 1 | 0 |
Cherry Red Spot Myoclonus Syndrome
[description not available] | 0 | 2.07 | 1 | 0 |
Hearing Loss
A general term for the complete or partial loss of the ability to hear from one or both ears. | 0 | 2.07 | 1 | 0 |
Muscle Relaxation
That phase of a muscle twitch during which a muscle returns to a resting position. | 0 | 2.04 | 1 | 0 |
Birth Weight
The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms. | 0 | 2.04 | 1 | 0 |
Muscular Dystrophy, Animal
MUSCULAR DYSTROPHY that occurs in VERTEBRATE animals. | 0 | 2.89 | 4 | 0 |
Idiopathic Inflammatory Myopathies
[description not available] | 0 | 1.98 | 1 | 0 |
Myositis
Inflammation of a muscle or muscle tissue. | 0 | 1.98 | 1 | 0 |
Infections, Retroviridae
[description not available] | 0 | 1.98 | 1 | 0 |
Retroviridae Infections
Virus diseases caused by the RETROVIRIDAE. | 0 | 1.98 | 1 | 0 |
Ovine Diseases
[description not available] | 0 | 2.39 | 2 | 0 |
Rigor Mortis
Muscular rigidity which develops in the cadaver usually from 4 to 10 hours after death and lasts 3 or 4 days. | 0 | 1.99 | 1 | 0 |
Cancer of Muscle
[description not available] | 0 | 1.99 | 1 | 0 |
Rhabdomyosarcoma
A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9) | 0 | 1.99 | 1 | 0 |
Chromosomal Fragility
[description not available] | 0 | 1.99 | 1 | 0 |
Gammapathy, Monoclonal
[description not available] | 0 | 2.92 | 1 | 0 |
HIV Coinfection
[description not available] | 0 | 2.92 | 1 | 0 |
Paraproteinemias
A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a structurally homogeneous immunoglobulin (M-component) and/or an abnormal immunoglobulin. | 0 | 2.92 | 1 | 0 |
HIV Infections
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS). | 0 | 2.92 | 1 | 0 |
Chromosome Deletion
Actual loss of portion of a chromosome. | 0 | 2.66 | 3 | 0 |