Page last updated: 2024-12-08
annetocin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
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Protein Interactions
Research Growth
Description
annetocin: an oxytocin-vasopressin related peptide from Eisenia foetida; potentiates spontaneous contractions of the gut , pulsatory contractions & bladder-shaking movement of the nephridia [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 197651 |
| SCHEMBL ID | 15511535 |
| MeSH ID | M0226512 |
Synonyms (7)
| Synonym |
|---|
| annetocin |
| (2s)-1-[(4r,7s,10s,13s,16s,19r)-19-amino-7-(2-amino-2-oxoethyl)-16-benzyl-10-[3-(diaminomethylideneamino)propyl]-6,9,12,15,18-pentaoxo-13-propan-2-yl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-n-[(2r,3r)-1-[(2-amino-2-oxoethyl)amino]-3-hydrox |
| 154445-03-1 |
| cyclo(cys-phe-val-arg-asn-cys)-pro-thr-gly-nh2 |
| oxytocin, 2-l-phenylalanine-3-l-valine-4-l-arginine-8-l-threonine- |
| SCHEMBL15511535 |
| DTXSID30165631 |
Research Excerpts
Overview
Annetocin is an earthworm oxytocin-related peptide that we previously isolated from the whole body of a lumbricid earthworm Eisenia foetida.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Annetocin is a structurally and functionally oxytocin-related peptide isolated from the earthworm Eisenia foetida. " | ( Evidence for conservation of the vasopressin/oxytocin superfamily in Annelida. Matsushima, O; Minakata, H; Satake, H; Takuwa, K, 1999) | 1.75 |
| "Annetocin is an earthworm oxytocin-related peptide that we previously isolated from the whole body of a lumbricid earthworm Eisenia foetida. " | ( Possible functions of oxytocin/vasopressin-superfamily peptides in annelids with special reference to reproduction and osmoregulation. Ando, M; Fujino, Y; Furukawa, Y; Matsushima, O; Minakata, H; Morishita, F; Nagahama, T; Nomoto, K; Oumi, T; Satake, H; Takahama, H; Ukena, K, 1999) | 1.75 |
Dosage Studied
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response relationship of the effects of annetocin and its related peptides on the annelid and mammalian systems shows that amino acid residue at the third position of these peptides is important for exertion of excitatory action on the smooth muscle systems." | ( Effects of annetocin, an oxytocin-related peptide isolated from the earthworm Eisenia foetida, and some putative neurotransmitters on gut motility of the earthworm. Fujita, T; Ikeda, T; Matsushima, O; Minakata, H; Nomoto, K; Oumi, T; Ukena, K, 1995) | 0.94 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (11)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 11 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||