Page last updated: 2024-12-08

n-acetyl-1,6-diaminohexane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID162081
CHEMBL ID177305
SCHEMBL ID285321
MeSH IDM0145096

Synonyms (20)

Synonym
49631-88-1
CHEMBL177305 ,
n-(6-aminohexyl)acetamide
AKOS006273181
n-acetyl-1,6-diaminohexane
n-acetyl-1,6-hexanediamine
acetamide, n-(6-aminohexyl)-
bdbm50405935
SCHEMBL285321
6-acetamidohexylamine
n-acetylhexylendiamine
WRJPJZTWQTUPQK-UHFFFAOYSA-N
acetamide,n-(6-aminohexyl)-
hexamethylendiamine monoacetamide
FT-0716694
DTXSID60964311
n-(6-aminohexyl)ethanimidic acid
mfcd00871149
D93510
AS-77339
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (1)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Peroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)Ki31.00000.10000.27670.5500AID144352
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (5)

Processvia Protein(s)Taxonomy
putrescine biosynthetic processPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
putrescine catabolic processPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
spermidine catabolic processPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
spermine catabolic processPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
positive regulation of spermidine biosynthetic processPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (6)

Processvia Protein(s)Taxonomy
polyamine oxidase activityPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activityPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
spermine:oxygen oxidoreductase (spermidine-forming) activityPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activityPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activityPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activityPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (2)

Processvia Protein(s)Taxonomy
peroxisomal matrixPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
cytosolPeroxisomal N(1)-acetyl-spermine/spermidine oxidaseHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID144352Ability to inhibit the deacetylation of [acetyl-3H]-N8-Acetylspermidine deacetylase in rat liver.1989Journal of medicinal chemistry, May, Volume: 32, Issue:5
Design and synthesis of inhibitors of N8-acetylspermidine deacetylase.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (33.33)18.7374
1990's4 (44.44)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.02

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.02 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.02)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]