methoxsalen has been researched along with Sensitivity and Specificity in 18 studies
Methoxsalen: A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA ADDUCTS in the presence of ultraviolet A irradiation.
methoxsalen : A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Ma, B | 1 |
| Zhang, Q | 1 |
| Yang, X | 1 |
| Sun, J | 1 |
| Tang, B | 1 |
| Cui, G | 1 |
| Yao, D | 1 |
| Liu, L | 1 |
| Gu, G | 1 |
| Zhu, J | 1 |
| Wei, P | 1 |
| Ouyang, P | 1 |
| Yadav, M | 1 |
| Contractor, P | 1 |
| Upadhyay, V | 1 |
| Gupta, A | 1 |
| Guttikar, S | 1 |
| Singhal, P | 1 |
| Goswami, S | 1 |
| Shrivastav, PS | 1 |
| Yang, W | 1 |
| Feng, C | 1 |
| Kong, D | 1 |
| Shi, X | 1 |
| Cui, Y | 1 |
| Liu, M | 1 |
| Wang, Q | 1 |
| Wang, Y | 1 |
| Zhang, L | 1 |
| Reus, AA | 1 |
| van Meeuwen, RN | 1 |
| de Vogel, N | 1 |
| Maas, WJ | 1 |
| Krul, CA | 1 |
| Ma, Y | 1 |
| Li, W | 1 |
| Hu, F | 1 |
| Shi, Y | 1 |
| Bi, Y | 1 |
| Feng, S | 1 |
| Leveque, N | 1 |
| Muret, P | 2 |
| Mary, S | 1 |
| Bérard, M | 1 |
| Makki, S | 3 |
| Pierre Kantelip, J | 1 |
| Humbert, P | 2 |
| Hamilton, KL | 1 |
| Butt, AG | 1 |
| Cheng, S | 1 |
| Carter, DJ | 1 |
| Klaschik, S | 1 |
| Lehmann, LE | 1 |
| Raadts, A | 1 |
| Hoeft, A | 1 |
| Stuber, F | 1 |
| Cardoso, CA | 2 |
| Pires, AE | 1 |
| Honda, NK | 2 |
| Jakobs, AE | 1 |
| Piette, J | 1 |
| Levy, E | 1 |
| Baroche, C | 1 |
| Barret, JM | 1 |
| Alapetite, C | 1 |
| Salles, B | 1 |
| Averbeck, D | 1 |
| Moustacchi, E | 1 |
| Keum, WK | 1 |
| Park, CE | 1 |
| Lee, JH | 2 |
| Khil, LY | 1 |
| Kang, I | 1 |
| Kim, SS | 1 |
| Jung, JC | 1 |
| Oh, SM | 1 |
| Woo, HJ | 1 |
| Kim, YC | 1 |
| Yoon, Y | 1 |
| Choi, JW | 1 |
| Ha, J | 1 |
| Saïd, A | 1 |
| Toubin, G | 1 |
| Millet, J | 1 |
| Mignot, B | 1 |
| Guillaume, Y | 1 |
| Murret, E | 1 |
| Cavalli, E | 1 |
| Truong, TT | 1 |
| Thomassin, M | 1 |
| Guinchard, C | 1 |
| Corless, CE | 1 |
| Guiver, M | 1 |
| Borrow, R | 1 |
| Edwards-Jones, V | 1 |
| Kaczmarski, EB | 1 |
| Fox, AJ | 1 |
| Yeo, UC | 1 |
| Shin, JH | 1 |
| Yang, JM | 1 |
| Park, KB | 1 |
| Kim, MM | 1 |
| Bok, HS | 1 |
| Lee, ES | 1 |
| Barison, A | 1 |
| Sharma, S | 1 |
| Das, D | 1 |
| Anand, R | 1 |
| Das, T | 1 |
| Kannabiran, C | 1 |
18 other studies available for methoxsalen and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous determination of osthole, bergapten and isopimpinellin in rat plasma and tissues by liquid chromatography-tandem mass spectrometry.
Topics: 5-Methoxypsoralen; Animals; Chromatography, Liquid; Coumarins; Female; Furocoumarins; Linear Models; | 2014 |
Automated liquid-liquid extraction based on 96-well plate format in conjunction with ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) for the quantitation of methoxsalen in human plasma.
Topics: Automation; Chromatography, Liquid; Humans; Methoxsalen; Photosensitizing Agents; Reference Standard | 2008 |
Simultaneous and sensitive determination of xanthotoxin, psoralen, isoimpinellin and bergapten in rat plasma by liquid chromatography-electrospray ionization mass spectrometry.
Topics: 5-Methoxypsoralen; Animals; Apiaceae; Chromatography, High Pressure Liquid; Ficusin; Furocoumarins; | 2010 |
Development and characterisation of an in vitro photomicronucleus test using ex vivo human skin tissue.
Topics: Adult; Cell Proliferation; Cell Survival; Drug Industry; Female; Gene Expression Regulation; Humans; | 2011 |
[Phamacokinetic study of bergapten in rats plasma by LC-MS/MS].
Topics: 5-Methoxypsoralen; Animals; Chromatography, Liquid; Male; Methoxsalen; Rats; Rats, Sprague-Dawley; R | 2012 |
Validation of a microdialysis-gas chromatographic-mass spectrometric method to assess 8-methoxypsoralen in psoriatic patient dermis.
Topics: Adult; Aged; Calibration; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Methoxsalen; M | 2002 |
Methoxsalen stimulates electrogenic Cl- secretion in the mouse jejunum.
Topics: Animals; Barium; Bumetanide; Chlorine; Colforsin; Dose-Response Relationship, Drug; Glyburide; In Vi | 2002 |
Comparison of different decontamination methods for reagents to detect low concentrations of bacterial 16S DNA by real-time-PCR.
Topics: Artifacts; Decontamination; Deoxyribonucleases; DNA Restriction Enzymes; DNA, Bacterial; Equipment C | 2002 |
A method for quantitative determination of furanocoumarins in capsules and tablets of phytochemical preparations.
Topics: 5-Methoxypsoralen; Benzopyrans; Capsules; Chromatography, High Pressure Liquid; Ficusin; Furocoumari | 2006 |
1-Thiomethoxsalen and 1-thiopsoralen: synthesis, photobiological properties, and site specific reaction of thiopsoralens with DNA.
Topics: Base Sequence; Binding Sites; Calcium; Cross-Linking Reagents; DNA Adducts; DNA Damage; DNA, Viral; | 1995 |
Activated ras oncogene and specifically acquired resistance to cisplatin in human mammary epithelial cells: induction of DNA cross-links and their repair.
Topics: Breast; Cell Division; Cell Line; Cell Line, Transformed; Cell Survival; Cell Transformation, Neopla | 1994 |
Primers determine the sensitivity of PCR-mediated hepatitis B virus DNA detection and pretreatment of PCR mixture with 8-methoxypsoralen eliminates false-positive results.
Topics: Base Sequence; DNA Primers; DNA, Viral; Evaluation Studies as Topic; False Positive Reactions; Hepat | 1997 |
Spectrofluorimetric determination of 5-methoxypsoralen pharmacokinetic in patients' serum.
Topics: 5-Methoxypsoralen; Administration, Oral; Calibration; Humans; Methanol; Methoxsalen; Photosensitizin | 1997 |
High-performance thin-layer chromatographic determination of 5-methoxypsoralen in serum from patients.
Topics: 5-Methoxypsoralen; Chromatography, Thin Layer; Humans; Methoxsalen; Psoriasis; PUVA Therapy; Reprodu | 1997 |
Contamination and sensitivity issues with a real-time universal 16S rRNA PCR.
Topics: Base Sequence; Conserved Sequence; DNA, Bacterial; Equipment Contamination; Escherichia coli; Methox | 2000 |
Psoralen-ultraviolet A-induced erythema: sensitivity correlates with the concentrations of psoralen in suction blister fluid.
Topics: Adolescent; Adult; Blister; Erythema; Female; Humans; Male; Methoxsalen; Middle Aged; Predictive Val | 2000 |
Simple and rapid determination of psoralens in topic solutions using liquid chromatography.
Topics: 5-Methoxypsoralen; Chromatography, High Pressure Liquid; Ficusin; Methoxsalen; Molecular Structure; | 2002 |
Reliability of nested polymerase chain reaction in the diagnosis of bacterial endophthalmitis.
Topics: Bacteria; Deoxyribonucleases, Type II Site-Specific; DNA, Bacterial; Endophthalmitis; Eye Infections | 2002 |