Page last updated: 2024-08-07 16:01:35
Neuromedin-K receptor
A neuromedin-K receptor that is encoded in the genome of rat. [OMA:P16177, PRO:DNx]
Synonyms
NKR;
NK-3 receptor;
NK-3R;
Neurokinin B receptor;
Tachykinin receptor 3
Research
Bioassay Publications (8)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (8)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| senktide | Rattus norvegicus (Norway rat) | IC50 | 0.0110 | 1 | 1 |
| 3,5-bis(trifluoromethyl)benzyl n-acetyltryptophan | Rattus norvegicus (Norway rat) | IC50 | 5.0000 | 1 | 1 |
| sr 142806 | Rattus norvegicus (Norway rat) | Ki | 0.0544 | 2 | 3 |
| sb 223412 | Rattus norvegicus (Norway rat) | Ki | 0.1942 | 2 | 3 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| substance p | Rattus norvegicus (Norway rat) | EC50 | 7.5000 | 1 | 1 |
| cp 96345 | Rattus norvegicus (Norway rat) | Kd | 2.5119 | 1 | 1 |
| senktide | Rattus norvegicus (Norway rat) | EC50 | 0.0068 | 2 | 2 |
| neurokinin a | Rattus norvegicus (Norway rat) | EC50 | 0.5630 | 1 | 1 |
| neurokinin b | Rattus norvegicus (Norway rat) | EC50 | 0.0063 | 1 | 1 |