Page last updated: 2024-12-06

trifluoroacetaldehyde

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Trifluoroacetaldehyde, also known as trifluoroethanal, is a highly reactive and unstable compound. It has been investigated as a potential synthetic intermediate due to the electron-withdrawing effect of the trifluoromethyl group. However, its instability makes its synthesis challenging and its handling hazardous. Studies on trifluoroacetaldehyde primarily focus on its theoretical properties and potential applications in organic synthesis. Its high reactivity and instability make it a challenging compound to work with, limiting its practical applications. Nonetheless, its unique properties continue to inspire research aimed at developing new synthetic methods and understanding its reaction mechanisms.'

Cross-References

ID SourceID
PubMed CID65564
MeSH IDM0155751

Synonyms (23)

Synonym
fluoral
nsc9446
acetaldehyde, trifluoro-
trifluoroacetaldehyde
nsc-9446
75-90-1
2,2,2-trifluoroethanone
2,2,2-trifluoroacetaldehyde
AKOS000121037
nsc 9446
acetaldehyde, 2,2,2-trifluoro-
einecs 200-914-1
BP-10050
FT-0647548
T3279
trifluoro-acetaldehyde
trifluoroethanone
DTXSID3058791
ethanal, trifluoro
trifluoroacetaldehyde monohydrate
trifluoracetaldehyde
A901558
EN300-21706

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" The enzymes involved in the toxic metabolic pathway have been investigated in this study."( Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol.
Dunbar, D; Fraser, JM; Kaminsky, LS; Seaman, M, 1992
)
0.28
" Administered TFE and TFAld were not toxic per se, since their toxicity and metabolism were inhibited by pyrazole."( 2,2,2-Trifluoroethanol intestinal and bone marrow toxicity: the role of its metabolism to 2,2,2-trifluoroacetaldehyde and trifluoroacetic acid.
Fraser, JM; Kaminsky, LS, 1988
)
0.49
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (16.67)18.7374
1990's2 (16.67)18.2507
2000's1 (8.33)29.6817
2010's5 (41.67)24.3611
2020's2 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 32.23

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index32.23 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index5.23 (4.65)
Search Engine Demand Index35.70 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (32.23)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]