flutamide has been researched along with Sensitivity and Specificity in 17 studies
Flutamide: An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effect of flutamide on vaginal histology, and to ascertain whether flutamide regulates body weight gain in the ovariectomized rat model." | 7.73 | Influence of ovariectomy and flutamide treatment on vaginal tissue and body weight. ( Gumusalan, Y; Ozbag, D; Ozdemir, N; Saruhan, BG, 2005) |
| "We hypothesized that administration of androgen receptors antagonist flutamide following trauma-hemorrhage (T-H) in metestrus females will maintain immune function and reduce remote organ damage under those conditions." | 7.73 | Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females. ( Chaudry, IH; Choudhry, MA; Hildebrand, F; Hubbard, WJ; Pape, HC; Thobe, BM, 2006) |
| "To determine the effect of flutamide on vaginal histology, and to ascertain whether flutamide regulates body weight gain in the ovariectomized rat model." | 3.73 | Influence of ovariectomy and flutamide treatment on vaginal tissue and body weight. ( Gumusalan, Y; Ozbag, D; Ozdemir, N; Saruhan, BG, 2005) |
| "We hypothesized that administration of androgen receptors antagonist flutamide following trauma-hemorrhage (T-H) in metestrus females will maintain immune function and reduce remote organ damage under those conditions." | 3.73 | Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females. ( Chaudry, IH; Choudhry, MA; Hildebrand, F; Hubbard, WJ; Pape, HC; Thobe, BM, 2006) |
| "For good prognosis metastatic prostate cancer patients under anti-androgen treatment, PSA response at 6 months with cut-off levels of < or = 1 ng/ml and < or = 10 ng/ml is prognostic for survival." | 2.71 | Prostate specific antigen: a prognostic marker of survival in good prognosis metastatic prostate cancer? (EORTC 30892). ( Collette, L; de Reijke, TM; Schröder, FH, 2003) |
| "Flutamide is a potent antiandrogen used for the treatment of prostatic cancer." | 1.31 | Determination of 2-hydroxyflutamide in human plasma by high-performance liquid chromatography and its application to pharmacokinetic studies. ( Daftsios, AC; Niopas, I, 2001) |
| "The accuracy of T staging for prostate cancer after NAH in MRI was 71%." | 1.31 | [Local staging with magnetic resonance imaging after neoadjuvant hormonal therapy for prostate cancer]. ( Ichijo, K; Mugiya, S; Nagae, H; Nagata, M; Sato, T; Un-no, T, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 10 (58.82) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Iwamura, A | 1 |
| Fukami, T | 1 |
| Hosomi, H | 1 |
| Nakajima, M | 1 |
| Yokoi, T | 1 |
| Schick, B | 1 |
| Dlugaiczyk, J | 1 |
| Wendler, O | 1 |
| Dasinger, JH | 1 |
| Intapad, S | 1 |
| Rudsenske, BR | 1 |
| Davis, GK | 1 |
| Newsome, AD | 1 |
| Alexander, BT | 1 |
| Yokomizo, Y | 1 |
| Kawahara, T | 1 |
| Miyoshi, Y | 1 |
| Otani, M | 1 |
| Yamanaka, S | 1 |
| Teranishi, J | 1 |
| Noguchi, K | 1 |
| Yao, M | 1 |
| Uemura, H | 1 |
| Zheng, H | 1 |
| Wu, D | 1 |
| Qian, ZY | 1 |
| Xiang, Y | 1 |
| Collette, L | 1 |
| de Reijke, TM | 1 |
| Schröder, FH | 1 |
| Saruhan, BG | 1 |
| Ozbag, D | 1 |
| Gumusalan, Y | 1 |
| Ozdemir, N | 1 |
| Hildebrand, F | 1 |
| Hubbard, WJ | 1 |
| Choudhry, MA | 1 |
| Thobe, BM | 1 |
| Pape, HC | 1 |
| Chaudry, IH | 1 |
| Tzanavaras, PD | 1 |
| Themelis, DG | 1 |
| Harnaen, EJ | 1 |
| Na, AF | 1 |
| Shenker, NS | 1 |
| Sourial, M | 1 |
| Farmer, PJ | 1 |
| Southwell, BR | 1 |
| Hutson, JM | 1 |
| Cooper, EH | 1 |
| Whelan, P | 1 |
| Purves, D | 1 |
| Gaido, KW | 1 |
| Leonard, LS | 1 |
| Lovell, S | 1 |
| Gould, JC | 1 |
| Babaï, D | 1 |
| Portier, CJ | 1 |
| McDonnell, DP | 1 |
| Yamada, T | 1 |
| Kunimatsu, T | 1 |
| Sako, H | 1 |
| Yabushita, S | 1 |
| Sukata, T | 1 |
| Okuno, Y | 1 |
| Matsuo, M | 1 |
| Nagahori, H | 1 |
| Komai, K | 1 |
| Tomigahara, Y | 1 |
| Saito, K | 1 |
| Isobe, N | 1 |
| Kaneko, H | 1 |
| Niopas, I | 1 |
| Daftsios, AC | 1 |
| Nagae, H | 1 |
| Sato, T | 1 |
| Nagata, M | 1 |
| Un-no, T | 1 |
| Mugiya, S | 1 |
| Ichijo, K | 1 |
1 trial available for flutamide and Sensitivity and Specificity
| Article | Year |
|---|---|
Prostate specific antigen: a prognostic marker of survival in good prognosis metastatic prostate cancer? (EORTC 30892).
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Bone Neoplasms; Cyprote | 2003 |
16 other studies available for flutamide and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay.
Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Cyclooxyge | 2011 |
Expression of sex hormone receptors in juvenile angiofibromas and antiproliferative effects of receptor modulators.
Topics: Adolescent; Angiofibroma; Antineoplastic Agents, Hormonal; Cell Proliferation; Flutamide; Gene Expre | 2014 |
Chronic Blockade of the Androgen Receptor Abolishes Age-Dependent Increases in Blood Pressure in Female Growth-Restricted Rats.
Topics: Animals; Animals, Newborn; Birth Weight; Blood Pressure Determination; Disease Models, Animal; Femal | 2016 |
Efficacy of Immediate Switching from Bicalutamide to Flutamide as Second-Line Combined Androgen Blockade.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Antineoplastic Agents; Biomarkers, Tumor; D | 2016 |
Determination of 2-hydroxyflutamide in human plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS): application to a bioequivalence study on Chinese volunteers.
Topics: Acetonitriles; China; Chromatography, Liquid; Drug Stability; Flutamide; Humans; Male; Reproducibili | 2010 |
Influence of ovariectomy and flutamide treatment on vaginal tissue and body weight.
Topics: Androgen Antagonists; Animals; Body Weight; Disease Models, Animal; Female; Flutamide; Immunohistoch | 2005 |
Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females.
Topics: Animals; Chemokine CCL2; Cytokines; Enzyme Activation; Estradiol; Female; Flow Cytometry; Flutamide; | 2006 |
Automated determination of flutamide by a validated flow-injection method: application to dissolution studies of pharmaceutical tablets.
Topics: Androgen Antagonists; Autoanalysis; Chromatography, High Pressure Liquid; Drug Stability; Flow Injec | 2007 |
The anatomy of the cremaster muscle during inguinoscrotal testicular descent in the rat.
Topics: Abdominal Muscles; Animals; Animals, Newborn; Cryptorchidism; Disease Models, Animal; Female; Flutam | 2007 |
Bone alkaline phosphatase and prostate-specific antigen in the monitoring of prostate cancer.
Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Biomarkers, Tumor; Bone and Bones; Bone Neoplasms; Cy | 1994 |
Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay.
Topics: DDT; Dose-Response Relationship, Drug; Endocrine Glands; Environmental Pollutants; Flutamide; Hormon | 1997 |
Comparative evaluation of a 5-day Hershberger assay utilizing mature male rats and a pubertal male assay for detection of flutamide's antiandrogenic activity.
Topics: Androgen Antagonists; Animals; Disease Models, Animal; Evaluation Studies as Topic; Flutamide; Lutei | 2000 |
Initial induction and subsequent reduction of alpha(2u)-globulin in urine and serum of mature male rats after repeated intraperitoneal injections of (anti)estrogen.
Topics: Alpha-Globulins; Animals; Benzhydryl Compounds; DDT; Dieldrin; Diethylstilbestrol; Dihydrotestostero | 2001 |
Determination of 2-hydroxyflutamide in human plasma by high-performance liquid chromatography and its application to pharmacokinetic studies.
Topics: Adult; Androgen Antagonists; Chromatography, High Pressure Liquid; Female; Flutamide; Humans; Male; | 2001 |
[Local staging with magnetic resonance imaging after neoadjuvant hormonal therapy for prostate cancer].
Topics: Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Chlormadinone Acetate; Flutamide; Human | 2001 |