Compounds > tetrahydrojateorrhizine
Page last updated: 2024-11-08

tetrahydrojateorrhizine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

corypalmine: from Corydalis chaerophylla (Fumariaceae); structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID185605
SCHEMBL ID231003
MeSH IDM0062567

Synonyms (42)

Synonym
corypalmine
6018-40-2
discretinine
AKOS000277451
tetrahydrojateorrhizine
27313-86-6
2,9,10-trimethoxy-6,8,13,13a-tetrahydro-5h-isoquinolino[2,1-b]isoquinolin-3-ol
dl-tetrahydrojatrorrhizine
dl-corypalmine
unii-60zpv7979l
6h-dibenzo(a,g)quinolizin-3-ol, 5,8,13,13a-tetrahydro-2,9,10-trimethoxy-
tetrahydrojatrorrhizine
60zpv7979l ,
corypalmine, (+/-)-
FT-0688342
FT-0624069
SCHEMBL231003
(+/-)-discretinine
5,8,13,13a-tetrahydro-2,9,10-trimethoxy-6h-dibenzo(a,g)quinolizin-3-ol
(+/-)-corypalmine
corypalmine dl-form [mi]
2,9,10-trimethoxyberbin-3-ol
(+/-)-tetrahydrojatrorrhizine
2,9,10-trimethoxy-5,8,13,13a-tetrahydro-6h-isoquino[3,2-a]isoquinolin-3-ol #
isoquino[2,1-b]isoquinoline, 4b,5,10,10a,11,12-hexahydro-2-hydroxy-3,8,9-tris(methoxy)-
BMCZTYDZHNTKPR-UHFFFAOYSA-N
13063-54-2
(r)-(+)-corypalmine
3,4,11-trimethoxy-7,8,12b,13-tetrahydro-5h-6-azatetraphen-10-ol
AS-72901
AKOS030633010
( inverted exclamation marka)-corypalmine
HY-N0654
corypalmin; corypalmine; corypalmine, (-)-; l-tetrahydrojatrorrhizine
CS-0009677
Q27263256
C74412
DTXSID30903555
noname_4241
(invertedexclamationmarka)-corypalmine
6h-dibenzo[a,g]quinolizin-3-ol, 5,8,13,13a-tetrahydro-2,9,10-trimethoxy-
B0005-129029
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.56

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.56 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.56)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
berberine
[no description available]		2.4920alkaloid antibiotic;
berberine alkaloid;
botanical anti-fungal agent;
organic heteropentacyclic compound		antilipemic drug;
antineoplastic agent;
antioxidant;
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor;
EC 1.21.3.3 (reticuline oxidase) inhibitor;
EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
EC 3.1.1.4 (phospholipase A2) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
hypoglycemic agent;
metabolite;
potassium channel blocker
bicuculline
Bicuculline: An isoquinoline alkaloid obtained from Dicentra cucullaria and other plants. It is a competitive antagonist for GABA-A receptors.. bicuculline : A benzylisoquinoline alkaloid that is 6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinoline which is substituted at the 5-pro-S position by a (6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl group. A light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.		2.0510benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines		agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin
n-methyllaurotetanine
N-methyllaurotetanine: structure in first source		2.1110
glaucine
glaucine: RN given refers to (+-)-isomer		2.0210aporphine alkaloid;
organic heterotetracyclic compound;
polyether;
tertiary amino compound		antibacterial agent;
antineoplastic agent;
antitussive;
muscle relaxant;
NF-kappaB inhibitor;
plant metabolite;
platelet aggregation inhibitor;
rat metabolite
berberrubine
berberrubine: RN refers to chloride salt; a protoberberine alkaloid antitumor agent which exhibits topoisomerase II poison activity as well as catalytic inhibition activity; structure in first source		2.0510
corydaline
[no description available]		2.0210isoquinoline alkaloid;
isoquinolines
corydalmine
corydalmine: antagonizes dopamine receptors; structure given in first source; RN given refers to (S)-isomer		2.1510
tetrahydropalmatine
[no description available]		2.4620
ConditionIndicatedRelationship StrengthStudiesTrials
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		02.1510