clofazimine has been researched along with Sensitivity and Specificity in 9 studies
Clofazimine: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
clofazimine : 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Excerpt | Relevance | Reference |
---|---|---|
"Prostate cancer was the most common form and had the second highest death rate of male cancer in the United States in 2015." | 1.51 | Photoacoustic imaging of clofazimine hydrochloride nanoparticle accumulation in cancerous vs normal prostates. ( Murashov, MD; Rosania, GR; Tan, JWY; Wang, X, 2019) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 5 (55.56) | 18.2507 |
2000's | 1 (11.11) | 29.6817 |
2010's | 3 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Li, W | 1 |
Doherty, J | 1 |
Fu, Y | 1 |
Flarakos, J | 1 |
Tan, JWY | 1 |
Murashov, MD | 1 |
Rosania, GR | 1 |
Wang, X | 1 |
Srikanth, CH | 1 |
Joshi, P | 1 |
Bikkasani, AK | 1 |
Porwal, K | 1 |
Gayen, JR | 1 |
Queiroz, RH | 1 |
Pereira, RC | 1 |
Gotardo, MA | 1 |
Cordeiro, DS | 1 |
Melchior, E | 1 |
Gomez-Flores, R | 1 |
Gupta, S | 1 |
Tamez-Guerra, R | 1 |
Mehta, RT | 1 |
O'Connor, R | 1 |
O'Sullivan, JF | 1 |
O'Kennedy, R | 1 |
Singh, HB | 1 |
Katoch, K | 1 |
Natrajan, M | 1 |
Sharma, RK | 1 |
Gupta, UD | 1 |
Sharma, VD | 1 |
Singh, D | 1 |
Chauhan, DS | 1 |
Srivastava, K | 1 |
Katoch, VM | 1 |
Krishnan, TR | 1 |
Abraham, I | 1 |
Williams, DL | 1 |
Gillis, TP | 1 |
Fiallo, P | 1 |
Job, CK | 1 |
Gelber, RH | 1 |
Hill, C | 1 |
Izumi, S | 1 |
9 other studies available for clofazimine and Sensitivity and Specificity
Article | Year |
---|---|
Quantitative analysis of clofazimine (Lamprene®), an antileprosy agent, in human dried blood spots using liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Clofazimine; Dried Blood Spot Testing; Drug Stability; Humans; Linear Models | 2018 |
Photoacoustic imaging of clofazimine hydrochloride nanoparticle accumulation in cancerous vs normal prostates.
Topics: Adenocarcinoma; Animals; Chlorides; Clofazimine; Contrast Media; Disease Models, Animal; Male; Mice; | 2019 |
Bone distribution study of anti leprotic drug clofazimine in rat bone marrow cells by a sensitive reverse phase liquid chromatography method.
Topics: Animals; Bone Marrow Cells; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Clo | 2014 |
Determination of clofazimine in leprosy patients by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Clofazimine; Drug Monitoring; Female; Humans; Leprostatic Agen | 2003 |
Determination of MICs for Mycobacterium avium-M. intracellulare complex in liquid medium by a colorimetric method.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biological Transport, Active; Clofazimine; Colorimetry | 1995 |
Determination of serum and tissue levels of phenazines including clofazimine.
Topics: Adipose Tissue; Animals; Chromatography, High Pressure Liquid; Clofazimine; Leprostatic Agents; Orga | 1996 |
Effect of treatment on PCR positivity in multibacillary leprosy patients treated with conventional and newer drugs ofloxacin and minocycline.
Topics: Adenosine Triphosphate; Biopsy; Clofazimine; Dapsone; DNA, Bacterial; Drug Evaluation; Drug Therapy, | 1999 |
A rapid and sensitive high performance liquid chromatographic analysis of clofazimine in plasma.
Topics: Animals; Chromatography, High Pressure Liquid; Clofazimine; Humans; Male; Rabbits; Reproducibility o | 1992 |
Detection of Mycobacterium leprae and the potential for monitoring antileprosy drug therapy directly from skin biopsies by PCR.
Topics: Anti-Bacterial Agents; Biopsy; Clofazimine; Dapsone; DNA Probes; DNA, Bacterial; Drug Therapy, Combi | 1992 |