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amiodarone and Sensitivity and Specificity

amiodarone has been researched along with Sensitivity and Specificity in 49 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
" The objective of the study was to assess the diagnostic accuracy of pCLE for amiodarone-related pneumonia (AMR-IP)."9.17In vivo probe-based confocal laser endomicroscopy in amiodarone-related pneumonia. ( Bergot, E; Bourg-Heckly, G; Dominique, S; Genevois, A; Jounieaux, V; Roussel, F; Salaün, M; Thiberville, L; Vergnon, JM; Vever-Bizet, C; Zalcman, G, 2013)
"To determine the incidence and predictability of amiodarone-induced thyrotoxicosis (AIT) and hypothyroidism (AIH) in patients with cardiomyopathy."9.13Incidence and predictability of amiodarone-induced thyrotoxicosis and hypothyroidism. ( Hofmann, A; Holzmannhofer, J; Nawara, C; Ofluoglu, S; Pirich, C; Strohmer, B, 2008)
" A measure of the optimum regression residual (r(opt)) has been calculated, discriminating between post-myocardial infarction patients at high and low risk of arrhythmic death while on treatment with amiodarone."9.11Characterization of QT interval adaptation to RR interval changes and its use as a risk-stratifier of arrhythmic mortality in amiodarone-treated survivors of acute myocardial infarction. ( Caminal, P; de Luna, AB; Laguna, P; Malik, M; Pueyo, E; Smetana, P, 2004)
"Distinguishing between amiodarone-induced thyrotoxicosis (AIT) caused by excessive hormone synthesis (AIT-1) or by a destructive process (AIT-2) has important therapeutic implications, but is still difficult and debated."7.88Amiodarone-Induced Thyrotoxicosis: Differential Diagnosis Using 99mTc-SestaMIBI and Target-to-Background Ratio (TBR). ( Barollo, S; Bertazza, L; Bodanza, V; Cavedon, E; Cecchin, D; Censi, S; Gusella, S; Manso, J; Mian, C; Watutantrige-Fernando, S, 2018)
"To determine how expert European thyroidologists assess and treat amiodarone-induced thyrotoxicosis (AIT)."7.72Diagnosis and management of amiodarone-induced thyrotoxicosis in Europe: results of an international survey among members of the European Thyroid Association. ( Bartalena, L; Bogazzi, F; Lai, A; Martino, E; Piantanida, E; Tanda, ML; Wiersinga, WM, 2004)
"To determine the efficacy necessary to make prophylactic ICD or amiodarone therapy cost-effective in patients with myocardial infarction."7.71Potential cost-effectiveness of prophylactic use of the implantable cardioverter defibrillator or amiodarone after myocardial infarction. ( Every, NR; Heidenreich, PA; Hlatky, MA; McDonald, KM; Owens, DK; Parsons, LS; Sanders, GD, 2001)
"Thirty consecutive patients with chronic rheumatic atrial fibrillation (AF) > or = 3 months after successful mitral valve surgery and left atrial diameter < or = 60 mm were treated with oral amiodarone."7.68Effectiveness of amiodarone and electrical cardioversion for chronic rheumatic atrial fibrillation after mitral valve surgery. ( Essop, MR; Röthlisberger, C; Sareli, P; Skoularigis, J; Skudicky, D; Wisenbaugh, T, 1993)
"Amiodarone therapy, especially chronic, can result in difficult ventricular fibrillation (VF) inductions during implantable cardioverter defibrillator (ICD) testing."5.17Effectiveness of VF induction with DC fibber versus conventional induction methods in patients on chronic amiodarone therapy. ( Gupta, MS; Kim, MH; Rubenstein, JC, 2013)
" The objective of the study was to assess the diagnostic accuracy of pCLE for amiodarone-related pneumonia (AMR-IP)."5.17In vivo probe-based confocal laser endomicroscopy in amiodarone-related pneumonia. ( Bergot, E; Bourg-Heckly, G; Dominique, S; Genevois, A; Jounieaux, V; Roussel, F; Salaün, M; Thiberville, L; Vergnon, JM; Vever-Bizet, C; Zalcman, G, 2013)
"To determine the incidence and predictability of amiodarone-induced thyrotoxicosis (AIT) and hypothyroidism (AIH) in patients with cardiomyopathy."5.13Incidence and predictability of amiodarone-induced thyrotoxicosis and hypothyroidism. ( Hofmann, A; Holzmannhofer, J; Nawara, C; Ofluoglu, S; Pirich, C; Strohmer, B, 2008)
"Analysing the Holter recordings collected at baseline during the European Myocardial Infarction Amiodarone Trial (EMIAT), we evaluate the possibility of using alpha, the slope of the power spectrum of heart rate variability signals (HRV) in the vicinity of f = 0, for postinfarction risk stratification."5.12HRV scaling exponent identifies postinfarction patients who might benefit from prophylactic treatment with amiodarone. ( Cerutti, S; Hnatkova, K; Malik, M; Sassi, R; Signorini, MG, 2006)
" A measure of the optimum regression residual (r(opt)) has been calculated, discriminating between post-myocardial infarction patients at high and low risk of arrhythmic death while on treatment with amiodarone."5.11Characterization of QT interval adaptation to RR interval changes and its use as a risk-stratifier of arrhythmic mortality in amiodarone-treated survivors of acute myocardial infarction. ( Caminal, P; de Luna, AB; Laguna, P; Malik, M; Pueyo, E; Smetana, P, 2004)
"The duration, severity, and cause of hypotension after intravenous amiodarone has not been well characterized in anesthetized cardiac surgical patients."5.10Acute circulatory actions of intravenous amiodarone loading in cardiac surgical patients. ( Augoustides, JG; Cheung, AT; Gardner, TJ; Harrington, A; Levy, WJ; Savino, JS; Weiss, SJ, 2003)
"Despite the antiarrhythmic efficacy of amiodarone, a definitive correlation between amiodarone treatment and increased non-arrhythmic mortality in patients with heart failure and depressed ventricular function has been reported."4.80Perspectives: does amiodarone increase non-sudden deaths? If so, why? ( Auricchio, A; Klein, HU; Nisam, S, 2000)
"Distinguishing between amiodarone-induced thyrotoxicosis (AIT) caused by excessive hormone synthesis (AIT-1) or by a destructive process (AIT-2) has important therapeutic implications, but is still difficult and debated."3.88Amiodarone-Induced Thyrotoxicosis: Differential Diagnosis Using 99mTc-SestaMIBI and Target-to-Background Ratio (TBR). ( Barollo, S; Bertazza, L; Bodanza, V; Cavedon, E; Cecchin, D; Censi, S; Gusella, S; Manso, J; Mian, C; Watutantrige-Fernando, S, 2018)
" We evaluated the clinical performance of nine FT4 assays in five centres, using a panel of 310 sera: 156 from euthyroid controls; 27 from hyperthyroid patients; 34 from untreated hypothyroidism; 22 from patients with renal failure; 30 from women in the last trimester of pregnancy; 23 from patients on thyroid substitutive therapy; and 18 from patients treated with amiodarone."3.72Clinical evaluation of nine free thyroxine assays: persistent problems in particular populations. ( Beaudonnet, A; d'Herbomez, M; Forzy, G; Gasser, F; Massart, C; Sapin, R, 2003)
"To determine how expert European thyroidologists assess and treat amiodarone-induced thyrotoxicosis (AIT)."3.72Diagnosis and management of amiodarone-induced thyrotoxicosis in Europe: results of an international survey among members of the European Thyroid Association. ( Bartalena, L; Bogazzi, F; Lai, A; Martino, E; Piantanida, E; Tanda, ML; Wiersinga, WM, 2004)
"To determine the efficacy necessary to make prophylactic ICD or amiodarone therapy cost-effective in patients with myocardial infarction."3.71Potential cost-effectiveness of prophylactic use of the implantable cardioverter defibrillator or amiodarone after myocardial infarction. ( Every, NR; Heidenreich, PA; Hlatky, MA; McDonald, KM; Owens, DK; Parsons, LS; Sanders, GD, 2001)
"We performed a methodological comparison of free triiodothyronine (FT3) estimates in patients with liver cirrhosis and renal failure."3.69Determination of free triiodothyronine by six different methods in patients with non-thyroidal illness and in patients treated with amiodarone. ( Chambron, J; Christofides, N; Gasser, F; Gervais, A; Kaltenbach, G; Petitjean, P; Roul, G; Sapin, R; Schlienger, JL, 1995)
"Three labeled-antibody immunoassays of free triiodothyronine (FT3) were studied in hyperthyroid patients, patients with nonthyroidal illness, and patients being treated with amiodarone; we also studied sera presenting known interferences (n for all groups = 465)."3.69Clinical comparison of three labeled-antibody immunoassays of free triiodothyronine. ( Cosson, E; d'Herbomez, M; Dilouya, A; Dumont, A; Helal, BO; Le Guillouzic, D; Lebtahi, R; Piketty, ML, 1996)
"Thirty consecutive patients with chronic rheumatic atrial fibrillation (AF) > or = 3 months after successful mitral valve surgery and left atrial diameter < or = 60 mm were treated with oral amiodarone."3.68Effectiveness of amiodarone and electrical cardioversion for chronic rheumatic atrial fibrillation after mitral valve surgery. ( Essop, MR; Röthlisberger, C; Sareli, P; Skoularigis, J; Skudicky, D; Wisenbaugh, T, 1993)
"To compare thyroid imaging using Tc-99m sestamibi with the standard Tc-99m pertechnetate scintigraphy in patients on chronic use of amiodarone."2.75Tc-99m sestamibi thyroid imaging in patients on chronic amiodarone treatment: a comparison with Tc-99m pertechnetate imaging. ( Amorim, BJ; Camargo, EE; de Almeida, EA; de Oliveira Santos, A; Etchebehere, EC; Guariento, MH; Lima, MC; Oki, GC; Ramos, CD; Tambascia, MA; Zantut-Wittmann, DE, 2010)
"Dronedarone was extracted using one-step liquid-liquid extraction."1.40Pharmacokinetics of dronedarone in rat using a newly developed high-performance liquid chromatographic assay method. ( Brocks, DR; Gabr, RQ; Jardan, YA, 2014)
" This novel HPLC method allows the fast and reliable determination of amiodarone and desethylamiodarone from several rat matrices (plasma, liver, kidneys, lungs and heart) and was successfully applied in a preliminary pharmacokinetic study."1.39A rapid HPLC method for the simultaneous determination of amiodarone and its major metabolite in rat plasma and tissues: a useful tool for pharmacokinetic studies. ( Alves, G; Falcão, A; Ferreira, A; Queiroz, J; Rodrigues, M, 2013)
"Phospholipidosis (PLD) is a topic of concern in drug development because it may be associated with toxicological consequences."1.37Comparison of a genomic and a multiplex cell imaging approach for the detection of phospholipidosis. ( Atienzar, FA; Cossu-Leguille, C; Depelchin, O; Dhalluin, S; Gerets, HH; Hanon, E; Tilmant, K; Vasseur, P, 2011)
"A dosing algorithm including genetic (VKORC1 and CYP2C9 genotypes) and nongenetic factors (age, weight, therapeutic indication, and cotreatment with amiodarone or simvastatin) explained 51% of the variance in stable weekly warfarin doses in 390 patients attending an anticoagulant clinic in a Brazilian public hospital."1.35Pharmacogenetics of warfarin: development of a dosing algorithm for brazilian patients. ( Dias-Neto, E; Ojopi, EB; Perini, JA; Rangel, F; Santana, IS; Silva-Assunção, E; Struchiner, CJ; Suarez-Kurtz, G, 2008)
"A rapid method for the quantification of amiodarone and desethylamiodarone in animal plasma using high-performance liquid chromatography combined with UV detection (HPLC-UV) is presented."1.33Determination of amiodarone and desethylamiodarone in horse plasma and urine by high-performance liquid chromatography combined with UV detection and electrospray ionization mass spectrometry. ( Baert, K; Croubels, S; De Backer, P; De Clercq, D; Deprez, P; Maes, A; van Loon, G, 2006)
"Amiodarone is a potent antiarrhythmic agent that is limited in clinical use by its adverse effects, including potentially life threatening amiodarone-induced pulmonary toxicity (AIPT)."1.32Value of technetium-99m diethyltriamine pentaaceticacid radioaerosol inhalation lung scintigraphy for the stage of amiodarone-induced pulmonary toxicity. ( Altaner, S; Altun, A; Berkada, S; Durmus-Altun, G; Ozbay, G; Sami Salihoglu, Y, 2004)
"Two simple, sensitive and economical spectrophotometric methods have been developed for the determination of amiodarone hydrochloride in pure form and commercial dosage form."1.32Validated spectrophotometric methods for the determination of amiodarone hydrochloride in commercial dosage forms using p-chloranilic acid and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone. ( Azmi, SN; Khan, NA; Rahman, N, 2004)
"Amiodarone (AMI) is a potent antiarrhythmic drug."1.31Metabolism of amiodarone. II. High-performance liquid chromatographic assay for mono-N-desethylamiodarone hydroxylation in liver microsomes. ( Bigler, L; Follath, F; Ha, HR; Kozlik, P; Stieger, B, 2001)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (16.33)18.2507
2000's28 (57.14)29.6817
2010's13 (26.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Passarelli, MK1
Pirkl, A1
Moellers, R1
Grinfeld, D1
Kollmer, F1
Havelund, R1
Newman, CF1
Marshall, PS1
Arlinghaus, H1
Alexander, MR1
West, A1
Horning, S1
Niehuis, E1
Makarov, A1
Dollery, CT1
Gilmore, IS1
Censi, S1
Bodanza, V1
Manso, J1
Gusella, S1
Watutantrige-Fernando, S1
Cavedon, E1
Barollo, S1
Bertazza, L1
Cecchin, D1
Mian, C1
Kahma, H1
Filppula, AM1
Launiainen, T1
Viinamäki, J1
Neuvonen, M1
Evangelista, EA1
Totah, RA1
Backman, JT1
Zao, CL1
Yang, YC1
Tomanek, L1
Cooke, A1
Berger, R1
Chien, LC1
Madigan, R1
Rubenstein, JC1
Gupta, MS1
Kim, MH1
Jardan, YA1
Gabr, RQ1
Brocks, DR2
Parekh, JM1
Sanyal, M1
Yadav, M1
Shrivastav, PS1
Carnicer-Lombarte, A1
Lancashire, HT1
Vanhoestenberghe, A1
Pérez-Ruiz, T2
Martínez-Lozano, C2
García-Martínez, MD1
Perini, JA1
Struchiner, CJ1
Silva-Assunção, E1
Santana, IS1
Rangel, F1
Ojopi, EB1
Dias-Neto, E1
Suarez-Kurtz, G1
Hofmann, A1
Nawara, C1
Ofluoglu, S1
Holzmannhofer, J1
Strohmer, B1
Pirich, C1
Oki, GC1
Zantut-Wittmann, DE1
de Oliveira Santos, A1
Guariento, MH1
Tambascia, MA1
de Almeida, EA1
Amorim, BJ1
Lima, MC1
Etchebehere, EC1
Camargo, EE1
Ramos, CD1
Tilmant, K1
Gerets, HH1
Dhalluin, S1
Hanon, E1
Depelchin, O1
Cossu-Leguille, C1
Vasseur, P1
Atienzar, FA1
Matsubara, K1
Sanoh, S1
Ohta, S1
Kitamura, S1
Sugihara, K1
Fujimoto, N1
Rodrigues, M1
Alves, G1
Ferreira, A1
Queiroz, J1
Falcão, A1
Salaün, M1
Roussel, F1
Bourg-Heckly, G1
Vever-Bizet, C1
Dominique, S1
Genevois, A1
Jounieaux, V1
Zalcman, G1
Bergot, E1
Vergnon, JM1
Thiberville, L1
Pollak, PT1
You, YD1
Cheung, AT1
Weiss, SJ1
Savino, JS1
Levy, WJ1
Augoustides, JG1
Harrington, A1
Gardner, TJ1
d'Herbomez, M2
Forzy, G1
Gasser, F2
Massart, C1
Beaudonnet, A1
Sapin, R2
Durmus-Altun, G2
Altun, A2
Sami Salihoglu, Y1
Altaner, S1
Berkada, S1
Ozbay, G1
Rahman, N1
Khan, NA1
Azmi, SN1
Pueyo, E1
Smetana, P1
Caminal, P1
de Luna, AB1
Malik, M2
Laguna, P1
Bartalena, L1
Wiersinga, WM1
Tanda, ML1
Bogazzi, F1
Piantanida, E1
Lai, A1
Martino, E1
Aktas, RG1
Salihoglu, YS1
Yigitbasi, NO1
Sassi, R1
Cerutti, S1
Hnatkova, K1
Signorini, MG1
Martín, J1
Ruiz, E1
Maes, A1
Baert, K1
Croubels, S1
De Clercq, D1
van Loon, G1
Deprez, P1
De Backer, P1
Shayeganpour, A1
Somayaji, V1
White, CM1
Schlienger, JL1
Kaltenbach, G1
Christofides, N1
Roul, G1
Gervais, A1
Petitjean, P1
Chambron, J1
Seidl, K1
Hauer, B1
Schwick, N1
Buechele, T1
Schilling, I1
Senges, J1
Skoularigis, J1
Röthlisberger, C1
Skudicky, D1
Essop, MR1
Wisenbaugh, T1
Sareli, P1
Piketty, ML1
Le Guillouzic, D1
Lebtahi, R1
Cosson, E1
Dumont, A1
Dilouya, A1
Helal, BO1
Hannak, D1
Scharbert, F1
Kattermann, R1
Valencia, M1
Zapata, V1
Bider, A1
Pérez-González, M1
Lamanna, V1
Endoh, Y1
Hanai, R1
Uto, K1
Tanaka, T1
Ohta, Y1
Kasanuki, H1
Ohnishi, S1
Auricchio, A1
Nisam, S1
Klein, HU1
Barbosa, EC1
Barbosa, PR1
Ginefra, P1
de Souza Bomfim, A1
Boghossian, SH1
da Rocha, PJ1
Filho, FM1
Kohno, N1
Yokoyama, A1
Kondo, K1
Ha, HR1
Kozlik, P1
Stieger, B1
Bigler, L1
Follath, F1
Michelucci, A1
Lazzeri, C1
Padeletti, L1
Bagliani, G1
Colella, A1
Sabini, A1
Zipoli, R1
Costoli, A1
Pieragnoli, P1
Gensini, GF1
Franchi, F1
Reithmann, C1
Dorwarth, U1
Gerth, A1
Remp, T1
Steinbeck, G1
Hoffmann, E1
Vernhet, H1
Bousquet, C1
Durand, G1
Giron, J1
Senac, JP1
Sanders, GD1
Hlatky, MA1
Every, NR1
McDonald, KM1
Heidenreich, PA1
Parsons, LS1
Owens, DK1
Kollroser, M1
Schober, C1
Hanioka, N1
Saito, Y1
Soyama, A1
Ando, M1
Ozawa, S1
Sawada, J1
Saavedra, I1
Ortiz, M1
Gaete, L1
Asenjo, R1
Biagini, L1
Ohar, JA1
Jackson, F1
Dettenmeier, PA1
Bedrossian, CW1
Tricomi, SM1
Evans, RG1
Larsen, GC1
Manolis, AS1
Sonnenberg, FA1
Beshansky, JR1
Estes, NA1
Pauker, SG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Endoscopic Follow-up of Low Grade Precancerous Bronchial Lesions in High Risk Patients (SELEPREBB1)[NCT00213603]365 participants (Actual)Observational2002-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for amiodarone and Sensitivity and Specificity

ArticleYear
[Ventricular arrhythmias after myocardial infarction: risk classification and treatment concepts].
    Deutsche medizinische Wochenschrift (1946), 1995, May-05, Volume: 120, Issue:18

    Topics: Adrenergic beta-Antagonists; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia A

1995
Perspectives: does amiodarone increase non-sudden deaths? If so, why?
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2000, Volume: 4, Issue:4

    Topics: Amiodarone; Anti-Arrhythmia Agents; Death, Sudden; Death, Sudden, Cardiac; Female; Heart Failure; Hu

2000

Trials

9 trials available for amiodarone and Sensitivity and Specificity

ArticleYear
Effectiveness of VF induction with DC fibber versus conventional induction methods in patients on chronic amiodarone therapy.
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2013, Volume: 38, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chronic Disease; Defibrillators,

2013
Incidence and predictability of amiodarone-induced thyrotoxicosis and hypothyroidism.
    Wiener klinische Wochenschrift, 2008, Volume: 120, Issue:15-16

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Austria; Female; Humans; Hypothyroidism; Incidence; Male;

2008
Tc-99m sestamibi thyroid imaging in patients on chronic amiodarone treatment: a comparison with Tc-99m pertechnetate imaging.
    Clinical nuclear medicine, 2010, Volume: 35, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chronic Disease; Female; Humans;

2010
In vivo probe-based confocal laser endomicroscopy in amiodarone-related pneumonia.
    The European respiratory journal, 2013, Volume: 42, Issue:6

    Topics: Aged; Aged, 80 and over; Amiodarone; Bronchoalveolar Lavage; Bronchoscopy; Female; Fluorescent Dyes;

2013
Acute circulatory actions of intravenous amiodarone loading in cardiac surgical patients.
    The Annals of thoracic surgery, 2003, Volume: 76, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Blood Pressure Determination; Cardiac Output; Coronary A

2003
Characterization of QT interval adaptation to RR interval changes and its use as a risk-stratifier of arrhythmic mortality in amiodarone-treated survivors of acute myocardial infarction.
    IEEE transactions on bio-medical engineering, 2004, Volume: 51, Issue:9

    Topics: Adaptation, Physiological; Algorithms; Amiodarone; Anti-Arrhythmia Agents; Causality; Comorbidity; D

2004
HRV scaling exponent identifies postinfarction patients who might benefit from prophylactic treatment with amiodarone.
    IEEE transactions on bio-medical engineering, 2006, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Aged; Algorithms; Amiodarone; Diagnosis, Computer-Assisted; Electrocardiography;

2006
Diagnostic accuracy of KL-6 as a marker of amiodarone-induced pulmonary toxicity.
    Pacing and clinical electrophysiology : PACE, 2000, Volume: 23, Issue:11 Pt 2

    Topics: Adult; Aged; Amiodarone; Antigens; Antigens, Neoplasm; Atrial Fibrillation; Biomarkers; C-Reactive P

2000
Early reinitiation of atrial fibrillation following external electrical cardioversion in amiodarone-treated patients.
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2001, Volume: 5, Issue:3

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Combined

2001

Other Studies

38 other studies available for amiodarone and Sensitivity and Specificity

ArticleYear
The 3D OrbiSIMS-label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power.
    Nature methods, 2017, Volume: 14, Issue:12

    Topics: Amiodarone; Animals; Cells, Cultured; Dopamine; Equipment Design; Female; gamma-Aminobutyric Acid; G

2017
Amiodarone-Induced Thyrotoxicosis: Differential Diagnosis Using 99mTc-SestaMIBI and Target-to-Background Ratio (TBR).
    Clinical nuclear medicine, 2018, Volume: 43, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Female; Humans; Male; Middle Aged

2018
Critical Differences between Enzyme Sources in Sensitivity to Detect Time-Dependent Inactivation of CYP2C8.
    Drug metabolism and disposition: the biological fate of chemicals, 2019, Volume: 47, Issue:4

    Topics: Amiodarone; Clopidogrel; Cytochrome P-450 CYP2C8; Gemfibrozil; Glucuronides; Humans; Kinetics; Micro

2019
PCR monitoring of parasitemia during drug treatment for canine Chagas disease.
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2019, Volume: 31, Issue:5

    Topics: Amiodarone; Animals; Chagas Disease; DNA, Kinetoplast; DNA, Protozoan; DNA, Satellite; Dog Diseases;

2019
Pharmacokinetics of dronedarone in rat using a newly developed high-performance liquid chromatographic assay method.
    Biomedical chromatography : BMC, 2014, Volume: 28, Issue:8

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Dronedarone; Liqu

2014
Systematic evaluation of plasma phospholipids for reliable and precise determination of dronedarone and desbutyldronedarone by LC-MS/MS.
    Bioanalysis, 2014, Volume: 6, Issue:19

    Topics: Amiodarone; Chromatography, Liquid; Dronedarone; Mass Spectrometry; Phospholipids; Sensitivity and S

2014
In vitro biocompatibility and electrical stability of thick-film platinum/gold alloy electrodes printed on alumina.
    Journal of neural engineering, 2017, Volume: 14, Issue:3

    Topics: Alloys; Aluminum Oxide; Amiodarone; Animals; Biocompatible Materials; Cell Survival; Electric Impeda

2017
Simultaneous determination of amiodarone and its metabolite desethylamiodarone by high-performance liquid chromatography with chemiluminescent detection.
    Analytica chimica acta, 2008, Aug-08, Volume: 623, Issue:1

    Topics: 2,2'-Dipyridyl; Amiodarone; Chromatography, High Pressure Liquid; Coordination Complexes; Humans; Lu

2008
Pharmacogenetics of warfarin: development of a dosing algorithm for brazilian patients.
    Clinical pharmacology and therapeutics, 2008, Volume: 84, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Ambulatory Care; Amiodarone; Analysis of Var

2008
Comparison of a genomic and a multiplex cell imaging approach for the detection of phospholipidosis.
    Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:7

    Topics: Amiodarone; Animal Testing Alternatives; Animals; Anti-Arrhythmia Agents; Fluorescent Dyes; Foam Cel

2011
An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide.
    Toxicology letters, 2012, Jan-05, Volume: 208, Issue:1

    Topics: Amiodarone; Animals; B-Cell Lymphoma 3 Protein; Biological Assay; Bithionol; Cell Line; Endocrine Di

2012
A rapid HPLC method for the simultaneous determination of amiodarone and its major metabolite in rat plasma and tissues: a useful tool for pharmacokinetic studies.
    Journal of chromatographic science, 2013, Volume: 51, Issue:4

    Topics: Amiodarone; Animals; Chromatography, High Pressure Liquid; Drug Stability; Linear Models; Liquid-Liq

2013
Monitoring of hepatic function during amiodarone therapy.
    The American journal of cardiology, 2003, Mar-01, Volume: 91, Issue:5

    Topics: Administration, Oral; Aged; Amiodarone; Analysis of Variance; Chemical and Drug Induced Liver Injury

2003
Clinical evaluation of nine free thyroxine assays: persistent problems in particular populations.
    Clinical chemistry and laboratory medicine, 2003, Volume: 41, Issue:7

    Topics: Amiodarone; Anti-Arrhythmia Agents; Blood Chemical Analysis; Female; Humans; Hyperthyroidism; Kidney

2003
Value of technetium-99m diethyltriamine pentaaceticacid radioaerosol inhalation lung scintigraphy for the stage of amiodarone-induced pulmonary toxicity.
    International journal of cardiology, 2004, Volume: 95, Issue:2-3

    Topics: Aerosols; Amiodarone; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Diagnosis, Differential

2004
Validated spectrophotometric methods for the determination of amiodarone hydrochloride in commercial dosage forms using p-chloranilic acid and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2004, Volume: 20, Issue:8

    Topics: Amiodarone; Anti-Arrhythmia Agents; Benzoquinones; Calibration; Dosage Forms; Molecular Structure; S

2004
Diagnosis and management of amiodarone-induced thyrotoxicosis in Europe: results of an international survey among members of the European Thyroid Association.
    Clinical endocrinology, 2004, Volume: 61, Issue:4

    Topics: Amiodarone; Europe; Humans; Iodine Radioisotopes; Radionuclide Imaging; Sensitivity and Specificity;

2004
Use of iodine-123 metaiodobenzylguanidine scintigraphy for the detection of amiodarone induced pulmonary toxicity in a rabbit model: a comparative study with technetium-99m diethyltriaminepenta acetic acid radioaerosol scintigraphy.
    Annals of nuclear medicine, 2005, Volume: 19, Issue:3

    Topics: 3-Iodobenzylguanidine; Aerosols; Amiodarone; Animals; Anti-Arrhythmia Agents; Injections, Intravenou

2005
Flow injection chemiluminescent determination of amiodarone in pharmaceutical preparations using photogenerated tris(2,2'-bipyridyl)ruthenium(III).
    Journal of pharmaceutical and biomedical analysis, 2006, Sep-11, Volume: 42, Issue:1

    Topics: Amiodarone; Flow Injection Analysis; Hydrogen-Ion Concentration; Luminescent Measurements; Organomet

2006
Determination of amiodarone and desethylamiodarone in horse plasma and urine by high-performance liquid chromatography combined with UV detection and electrospray ionization mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, May-19, Volume: 836, Issue:1-2

    Topics: Amiodarone; Animals; Chromatography, High Pressure Liquid; Horses; Reference Standards; Sensitivity

2006
A liquid chromatography-mass spectrometry assay method for simultaneous determination of amiodarone and desethylamiodarone in rat specimens.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:3

    Topics: Amiodarone; Animals; Calibration; Chromatography, High Pressure Liquid; Injections, Intravenous; Lin

2007
Is dronedarone effective for the prevention of recurrent atrial fibrillation?
    Nature clinical practice. Cardiovascular medicine, 2008, Volume: 5, Issue:3

    Topics: Amiodarone; Atrial Fibrillation; Confidence Intervals; Dose-Response Relationship, Drug; Double-Blin

2008
Determination of free triiodothyronine by six different methods in patients with non-thyroidal illness and in patients treated with amiodarone.
    Annals of clinical biochemistry, 1995, Volume: 32 ( Pt 3)

    Topics: Adult; Aged; Amiodarone; Humans; Immunoassay; Liver Cirrhosis; Middle Aged; Renal Insufficiency; Sen

1995
Effectiveness of amiodarone and electrical cardioversion for chronic rheumatic atrial fibrillation after mitral valve surgery.
    The American journal of cardiology, 1993, Aug-15, Volume: 72, Issue:5

    Topics: Adult; Amiodarone; Atrial Fibrillation; Chronic Disease; Combined Modality Therapy; Electric Counter

1993
Clinical comparison of three labeled-antibody immunoassays of free triiodothyronine.
    Clinical chemistry, 1996, Volume: 42, Issue:6 Pt 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Autoanalysis; Autoantibodies; Humans; Hypert

1996
Stepwise binary gradient high-performance liquid chromatographic system for routine drug monitoring.
    Journal of chromatography. A, 1996, Mar-29, Volume: 728, Issue:1-2

    Topics: Amiodarone; Chemical Precipitation; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; I

1996
[Measurement of serum amiodarone by protein precipitation followed by high performance liquid chromatography with ultraviolet detection].
    Acta cientifica venezolana, 2000, Volume: 51, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Chemical Precipitation; Chromatography, High Pressure Liquid; Co

2000
The frequency analysis of signal-averaged ECG of P wave as predictor of efficacy of class III antiarrhythmic drugs to maintain sinus rhythm in recurrent idiopathic atrial fibrillation.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2001, Volume: 6, Issue:1

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Female; Humans;

2001
KL-6 as a serum marker for amiodarone-induced pulmonary toxicity.
    Internal medicine (Tokyo, Japan), 2000, Volume: 39, Issue:12

    Topics: Amiodarone; Anti-Arrhythmia Agents; Antigens; Antigens, Neoplasm; Biomarkers; Diagnosis, Differentia

2000
Metabolism of amiodarone. II. High-performance liquid chromatographic assay for mono-N-desethylamiodarone hydroxylation in liver microsomes.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Jun-15, Volume: 757, Issue:2

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Biotransformation; Chromatography, High Pressure Liquid

2001
Altered values of heart rate variability in patients with relapse of atrial fibrillation during the first week after electrical cardioversion: preliminary data.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2001, Volume: 2, Issue:6

    Topics: Aged; Amiodarone; Atrial Fibrillation; Circadian Rhythm; Electric Countershock; Electrocardiography,

2001
Reversible amiodarone-induced lung disease: HRCT findings.
    European radiology, 2001, Volume: 11, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Male; Middle Aged; Pulmonary Fibrosis; Rad

2001
Potential cost-effectiveness of prophylactic use of the implantable cardioverter defibrillator or amiodarone after myocardial infarction.
    Annals of internal medicine, 2001, Nov-20, Volume: 135, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cost-Benef

2001
Determination of amiodarone and desethylamiodarone in human plasma by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry with an ion trap detector.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002, Jan-25, Volume: 766, Issue:2

    Topics: Amiodarone; Chromatography, High Pressure Liquid; Humans; Reference Standards; Reproducibility of Re

2002
High-performance liquid chromatographic assay for amiodarone N-deethylation activity in human liver microsomes using solid-phase extraction.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002, Jul-05, Volume: 774, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Humans; Microsomes, Liver;

2002
[Determination of plasma concentration of amiodarone and desethylamiodarone with high pressure liquid chromatography. Preliminary experience].
    Revista medica de Chile, 1992, Volume: 120, Issue:6

    Topics: Adult; Aged; Amiodarone; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Se

1992
Bronchoalveolar lavage cell count and differential are not reliable indicators of amiodarone-induced pneumonitis.
    Chest, 1992, Volume: 102, Issue:4

    Topics: Aged; Amiodarone; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cell Count; Humans; Middle Aged; Predi

1992
Cost-effectiveness of the implantable cardioverter-defibrillator: effect of improved battery life and comparison with amiodarone therapy.
    Journal of the American College of Cardiology, 1992, Volume: 19, Issue:6

    Topics: Amiodarone; Cost-Benefit Analysis; Costs and Cost Analysis; Death, Sudden, Cardiac; Decision Support

1992