Page last updated: 2024-12-06
irganox 1010
Description
Research Excerpts
Clinical Trials
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Occurs in Manufacturing
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Description
Irganox 1010, also known as pentaerythritol tetrakis(3,5-di-tert-butyl-4-hydroxyhydrocinnamate), is a hindered phenolic antioxidant widely used in polymers and other materials to prevent degradation caused by oxidation. It is synthesized through a multi-step process involving the reaction of pentaerythritol with 3,5-di-tert-butyl-4-hydroxyhydrocinnamic acid. Irganox 1010 effectively scavenges free radicals, thereby inhibiting chain reactions that lead to polymer degradation. Its high effectiveness and compatibility with various polymers have made it a crucial component in numerous applications, including plastics, rubber, and fuels. Research on Irganox 1010 focuses on understanding its mechanism of action, optimizing its performance, and exploring potential environmental and health effects. The compound's impact on the environment and potential toxicity are areas of ongoing study.'
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pentaerythritol tetrakis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate): has antioxidant activity [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 64819 |
| CHEMBL ID | 3187856 |
| SCHEMBL ID | 30209 |
| MeSH ID | M0132908 |
Synonyms (100)
| Synonym |
|---|
| AC-15274 |
| AKOS005444166 |
| irganox 1010 |
| hydrocinnamic acid, 3,5-di-tert-butyl-4-hydroxy-, tetraester with pentaerythritol |
| naugard 10 |
| ra 1010 |
| irganox 1010ff |
| irganox 1010fp |
| phenosane 23 |
| einecs 229-722-6 |
| fenozan 22 |
| tetrakis(3-(4-hydroxy-3,5-di-tert-butylphenyl)propionyloxymethyl)methane |
| ralox 630 |
| sumilizer bp 101 |
| pentaerythritol, tetrakis(3,5-di-tert-butyl-4-hydroxyhydrocinnamate) |
| dovernox 10 |
| neopentanetetrayl 3,5-di-tert-butyl-4-hydroxyhydrocinnamate |
| phenosan-23 |
| tetrakis(methylene(3,5-di-tert-butyl-4-hydroxyhydrocinnamate)methane |
| irganox 1040 |
| benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 2,2-bis((3-(3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)-1-oxopropoxy)methyl)-1,3-propanediyl ester |
| anox 20 |
| hydrocinnamic acid, 3,5-di-tert-butyl-4-hydroxy-, neopentanetetrayl ester |
| anox 20am |
| tetrakis(((beta-(3,5-di-tert-butyl-4-hydroxyphenyl)propionyl)oxy)methyl)methane |
| mark ao 60 |
| tetrakis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyloxymethyl)methane |
| ao 60 |
| adk stab ao 60 |
| brn 2035465 |
| ir 1010 |
| tetraalkofen bpe |
| bp 101 |
| fenozan 23 |
| pentaerythritol tetrakis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate) |
| STK367172 |
| pentaerythritol tetrakis(3,5-di-tert-butyl-4-hydroxyhydrocinnamate), 98% |
| AO3 , |
| benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 2,2-bis[[3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-1-oxopropoxy]methyl]-1,3-propanediyl ester |
| 3-{[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl]oxy}-2,2-bis({[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl]oxy}methyl)propyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate |
| 6683-19-8 |
| [3-[3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoyloxy]-2,2-bis[3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoyloxymethyl]propyl] 3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoate |
| FT-0659922 |
| tetrakis[methylene-3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate]methane |
| P0932 |
| pentaerythritol tetrakis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate] |
| dtxsid1027633 , |
| tox21_301970 |
| NCGC00255211-01 |
| cas-6683-19-8 |
| dtxcid007633 |
| ec 229-722-6 |
| pentaerithritol tetrakis(3,5-di-tert-butyl-4-hydroxyhydrocinnamate) |
| 255pif62ms , |
| benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 1,1'-(2,2-bis((3-(3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)-1-oxopropoxy)methyl)-1,3-propanediyl) ester |
| unii-255pif62ms |
| 2,2-bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) |
| pentaerythrityl tetrakis(3,5-di-tert-butyl-4-hydroxyhydrocinnamate) |
| pentaerythritol 4-hydroxy-3,5-di-tert-butylphenylpropionate |
| pentaerythritol 3-(4-hydroxy-3,5-di-tert-butylphenyl)propionate (1:4) |
| pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate |
| plastic additive 2 |
| pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate [inci] |
| pentaerythrityl tetrakis(3,5-di-tert- butyl-4-hydroxyhydrocinnamate) |
| pentaerythrityl tetrakis (3,5-di-tert-butyl-4-hydroxyhydrocinnamate) |
| antioxidant 1010 , |
| irganox-1010 |
| pentaerythritol tetrakis ester with 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid |
| plastic additive 2 [usp-rs] |
| tinogard ttdd |
| tinogard tt |
| pentaerthrityl tetra-di-t-butyl hydroxyhydrocinnamate |
| pentaerythritol tetrakis(3,5-di-tert-butyl-4-hydroxyhydrocinnamate) |
| pentaerithritol tetrakis[3,5-di-tert-butyl-4-hydroxyhydrocinnamate] |
| SCHEMBL30209 |
| W-104737 |
| 3-([3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoyl]oxy)-2,2-bis(([3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoyl]oxy)methyl)propyl 3-(3,5-ditert-butyl-4-hydroxyphenyl)propanoate # |
| benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, 1,1'-[2,2-bis[[3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-1-oxopropoxy]methyl]-1,3-propanediyl] ester |
| tetrakis [methylene (3,5-di-t-butyl-4-hydroxyhydrocinnamate)] methane |
| pentaerythritol tetrakis[3-(3',5'-di-tert-butyl-4'-hydroxyphenyl)propionate] |
| pentaerythrityl tetrakis-3-(3',5'-di-t-butyl-4'-hydroxyphenyl)propionate |
| lowinox pp35 |
| tetrakis[methylene(3,5-di-tert-butyl-4-hydroxyhydrocinnamate)methane] |
| CHEMBL3187856 |
| mfcd00059345 |
| plastic additive 2, united states pharmacopeia (usp) reference standard |
| plastic additive 09, european pharmacopoeia (ep) reference standard |
| 2,2-bis((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyloxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) |
| 2,2-bis[[[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl]oxy]methyl]propane-1,3-diyl bis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate] |
| SY052363 |
| irganox1010 |
| AS-13857 |
| AMY37985 |
| Q27253913 |
| CS-W011369 |
| 2,2-bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diylbis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) |
| tetrakis-(methylene-(3,5-di-(tert)-butyl-4-hydrocinnamate)) methane |
| plastic additive 2 (usp-rs) |
| PD132638 |
| tetrakis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionyloxymethyl]methane |
Research Excerpts
Overview
Irganox 1010 is a common commercial antioxidant (polymer additive) used in the manufacturing of polyolefin materials for container closure systems.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Irganox 1010 is a common commercial antioxidant (polymer additive) used in the manufacturing of polyolefin materials for container closure systems." | ( Identification of leachable impurities in an ophthalmic drug product originating from a polymer additive Irganox 1010 using mass spectroscopy. Blinder, A; Gollapalli, R; Patel, M; Singh, G, 2018) | 1.42 |
Dosage Studied
| Excerpt | Relevance | Reference |
|---|---|---|
| " A cell culture irritation test was dosed with a positive control, negative control and PTTC." | ( Localized delivery of a lipophilic proteasome inhibitor into human skin for treatment of psoriasis. Arbiser, J; Banga, AK; Coulon, R; Gujjar, M, 2016) | 0.43 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Occurs in Manufacturing (3 Product(s))
Product Categories
| Product Category | Products |
|---|---|
| Beauty & Personal Care | 3 |