Proteins > Stimulator of interferon genes protein
Page last updated: 2024-08-07 10:23:03
Stimulator of interferon genes protein
A transmembrane protein 173 that is encoded in the genome of mouse. [OMA:Q3TBT3, PRO:DNx]
Synonyms
mSTING;
Endoplasmic reticulum interferon stimulator;
ERIS;
Mediator of IRF3 activation;
MMITA;
Transmembrane protein 173
Research
Bioassay Publications (6)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 4 (66.67) | 2.80 |
Compounds (6)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| vadimezan | Mus musculus (house mouse) | IC50 | 1.2000 | 1 | 1 |
Drugs with Activation Measurements
Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration.European journal of medicinal chemistry, , Aug-05, Volume: 238, 2022
Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective.Journal of medicinal chemistry, , 04-23, Volume: 63, Issue:8, 2020
Interrupting cyclic dinucleotide-cGAS-STING axis with small molecules.MedChemComm, , Dec-01, Volume: 10, Issue:12, 2019
Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration.European journal of medicinal chemistry, , Aug-05, Volume: 238, 2022
Discovery of Non-Nucleotide Small-Molecule STING Agonists Journal of medicinal chemistry, , 02-24, Volume: 65, Issue:4, 2022
Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective.Journal of medicinal chemistry, , 04-23, Volume: 63, Issue:8, 2020
Interrupting cyclic dinucleotide-cGAS-STING axis with small molecules.MedChemComm, , Dec-01, Volume: 10, Issue:12, 2019
[no title available]Journal of medicinal chemistry, , 11-23, Volume: 59, Issue:22, 2016
Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer.Journal of medicinal chemistry, , 04-14, Volume: 65, Issue:7, 2022
[no title available]Journal of medicinal chemistry, , 11-23, Volume: 59, Issue:22, 2016