Proteins > 4-aminobutyrate aminotransferase, mitochondrial
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4-aminobutyrate aminotransferase, mitochondrial
A 4-aminobutyrate aminotransferase, mitochondrial that is encoded in the genome of pig. [OMA:P80147, PRO:DNx]
Synonyms
EC 2.6.1.19;
(S)-3-amino-2-methylpropionate transaminase;
2.6.1.22;
GABA aminotransferase;
GABA-AT;
Gamma-amino-N-butyrate transaminase;
GABA transaminase;
GABA-T;
L-AIBAT
Research
Bioassay Publications (9)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
Compounds (5)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
Drugs with Other Measurements
Synthesis and evaluation of novel heteroaromatic substrates of GABA aminotransferase.Bioorganic & medicinal chemistry, , Oct-01, Volume: 20, Issue:19, 2012
Inhibition and substrate activity of conformationally rigid vigabatrin analogues with gamma-aminobutyric acid aminotransferase.Journal of medicinal chemistry, , Nov-04, Volume: 42, Issue:22, 1999
2,6-Difluorophenol as a bioisostere of a carboxylic acid: bioisosteric analogues of gamma-aminobutyric acid.Journal of medicinal chemistry, , Jan-28, Volume: 42, Issue:2, 1999
4-Amino-2-(substituted methyl)-2-butenoic acids: substrates and potent inhibitors of gamma-aminobutyric acid aminotransferase.Journal of medicinal chemistry, , Volume: 29, Issue:5, 1986
Mechanism-Based Design of 3-Amino-4-Halocyclopentenecarboxylic Acids as Inactivators of GABA Aminotransferase.ACS medicinal chemistry letters, , Oct-08, Volume: 11, Issue:10, 2020
Design, synthesis, and biological activity of a difluoro-substituted, conformationally rigid vigabatrin analogue as a potent gamma-aminobutyric acid aminotransferase inhibitor.Journal of medicinal chemistry, , Dec-04, Volume: 46, Issue:25, 2003
A new class of conformationally rigid analogues of 4-amino-5-halopentanoic acids, potent inactivators of gamma-aminobutyric acid aminotransferase.Journal of medicinal chemistry, , Feb-24, Volume: 43, Issue:4, 2000
Inactivation of gamma-aminobutyric acid aminotransferase by (S,E)-4-amino-5-fluoropent-2-enoic acid and effect on the enzyme of (E)-3-(1-aminocyclopropyl)-2-propenoic acid.Journal of medicinal chemistry, , Volume: 29, Issue:10, 1986