Page last updated: 2024-11-12

p 829

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

P 829: amino acid sequence in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9898619
CHEMBL ID1908335
CHEBI ID135908
SCHEMBL ID456503
MeSH IDM0263746

Synonyms (33)

Synonym
161982-62-3
depreotide (usan/inn)
D03687
CHEBI:135908
p-829
unii-ndp0h8e844
ndp0h8e844 ,
p 829
lysyl-cysteinyl-lysyl-(beta-dap) cyclo(homocysteinyl-(n-methyl)phenylalanyl-tyrosyl-tryptophyl-lysyl-valyl)thiomethyl ketone
cyclo(l-homocysteinyl-n-methyl-l-phenylalanyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl) (1-1')-sulfide with 3-((mercaptoacetyl)amino)-l-alanyl-l-lysyl-l-cysteinyl-l-lysinamide
cyclo(l-homocysteinyl-n-methyl-l-phenylalanyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl), (1-1')-sulfide with 3-(2-mercaptoacetamido)-l-alanyl-l-lysyl-l-cysteinyl-l-lysinamide
p829 cpd
depreotide [usan:inn]
lys-cys-lys-(beta-dap)-ch2co-s-cyclo(hcys-(n-me)phe-tyr-trp-lys-val)
p829
depreotide
cyclo(l-homocysteinyl-n-methyl-l-phenylalanyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl), (1-1')-thioether with 3-((mercaptoacetyl)amino)-l-alanyl-l-lysyl-l-cysteinyl-l-lysinamide
CHEMBL1908335
depreotide [usan]
cyclo(l-homocysteinyl-n-methyl-l-phenylalanyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl), (1->1')-sulfide with 3-(2-mercaptoacetamido)-l-alanyl-l-lysyl-l-cysteinyl-l-lysinamide
depreotide [inn]
cyclo(l-homocysteinyl-n-methyl-l-phenylalanyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl), (1->1')-sulphide with 3-(2-mercaptoacetamido)-l-alanyl-l-lysyl-l-cysteinyl-l-lysinamide
cyclo(l-homocysteinyl-n-methyl-l-phenylalanyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl) (1->1')-sulphide with 3-((mercaptoacetyl)amino)-l-alanyl-l-lysyl-l-cysteinyl-l-lysinamide
depreotide [who-dd]
depreotide [mi]
cyclo(l-homocysteinyl-n-methyl-l-phenylalanyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl) (1->1')-sulfide with 3-((mercaptoacetyl)amino)-l-alanyl-l-lysyl-l-cysteinyl-l-lysinamide
SCHEMBL456503
DB11628
(2s)-6-amino-2-[[(2r)-2-[[(2s)-6-amino-2-[[(2s)-2-amino-3-[[2-[2-[(2s,5s,8s,11r,14s,17s)-14-(4-aminobutyl)-5-benzyl-8-[(4-hydroxyphenyl)methyl]-11-(1h-indol-3-ylmethyl)-4-methyl-3,6,9,12,15,18-hexaoxo-17-propan-2-yl-1,4,7,10,13,16-hexazacyclooctadec-2-yl]
Q27284812
DTXSID301026951
CS-0069943
HY-114133
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
oligopeptideA peptide containing a relatively small number of amino acids.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID297465Ratio of drug level in tumor to muscle of rat AR42J tumor bearing mouse2007Journal of medicinal chemistry, Sep-06, Volume: 50, Issue:18
Isolation, characterization, and biological evaluation of syn and anti diastereomers of [(99m)Tc]technetium depreotide: a somatostatin receptor binding tumor imaging agent.
AID297463Biodistribution in tumor of rat AR42J tumor bearing mouse2007Journal of medicinal chemistry, Sep-06, Volume: 50, Issue:18
Isolation, characterization, and biological evaluation of syn and anti diastereomers of [(99m)Tc]technetium depreotide: a somatostatin receptor binding tumor imaging agent.
AID297466Biodistribution in tumor of rat AR42J tumor bearing mouse in presence of octreotide2007Journal of medicinal chemistry, Sep-06, Volume: 50, Issue:18
Isolation, characterization, and biological evaluation of syn and anti diastereomers of [(99m)Tc]technetium depreotide: a somatostatin receptor binding tumor imaging agent.
AID297462Displacement of [125I]somatostatin from SSTR in rat AR42J cells2007Journal of medicinal chemistry, Sep-06, Volume: 50, Issue:18
Isolation, characterization, and biological evaluation of syn and anti diastereomers of [(99m)Tc]technetium depreotide: a somatostatin receptor binding tumor imaging agent.
AID297464Ratio of drug level in tumor to blood of rat AR42J tumor bearing mouse2007Journal of medicinal chemistry, Sep-06, Volume: 50, Issue:18
Isolation, characterization, and biological evaluation of syn and anti diastereomers of [(99m)Tc]technetium depreotide: a somatostatin receptor binding tumor imaging agent.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's4 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 27.74

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index27.74 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.27 (4.65)
Search Engine Demand Index26.69 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (27.74)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials3 (37.50%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (62.50%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]